Containing Or Obtained From A Flower Or Blossom (aka Flos) Patents (Class 424/778)
  • Patent number: 11234924
    Abstract: The present invention discloses an organic skin moisturizer, which extends and improves the skin cells. The composition is dermatologically acceptable and is capable of moisturizing skin for at least twelve hours after topical application to skin even after multiple washings of the skin.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: February 1, 2022
    Inventor: Tova Palomino
  • Patent number: 10918650
    Abstract: The invention pertains to a method of treating melanoma by administering to a subject in need thereof, a composition comprising a therapeutically effective amount of an inhibitor of PKC-? and/or PKC-?. Non-limiting examples of an inhibitor of PKC-? and/or PKC-? include ICA-1 and ACPD. The invention also provides PKC-? and/or PKC-? as biomarkers for identifying a melanoma in a subject as likely to be responsive or non-responsive to a therapy using an inhibitor of PKC-? and/or PKC-?. Accordingly, a method of identifying a subject having a melanoma as being responsive or non-responsive to a melanoma therapy with an inhibitor of PKC-? and/or PKC-? based on the levels and/or activity of PKC-? and/or PKC-? mRNA or protein in the melanoma cells from the subject are also provided.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: February 16, 2021
    Assignees: UNIVERSITY OF SOUTH FLORIDA, UNIVERSITY OF FLORIDA RESEARCH FOUNDATION. INC.
    Inventors: Mildred Enid Acevedo-Duncan, Wishrawana Ratnayake, David A. Ostrov
  • Patent number: 10780041
    Abstract: A method of whitening skin or evening out skin tone is disclosed. The method can include topically applying to skin in need of treatment a composition comprising an effective amount of an aqueous extract of white navy bean powder, wherein topical application of the composition whitens skin or evens out skin tone.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: September 22, 2020
    Assignee: Mary Kay Inc.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Patent number: 10765966
    Abstract: The disclosure includes a method of using a biomass extraction and centrifugation system to extract and centrifuge biomass. In some embodiments, the method comprises loading a first portion of biomass into a vessel and loading a first portion of solvent into the vessel, and holding the first portion of biomass and the first portion of solvent in the vessel for a predetermined amount of time, whereby the first portion of biomass and the first portion of solvent define a first slurry of a first cycle. Accordingly, in some embodiments, the method comprises extracting at least a portion of a biomass extraction from the first slurry, and separating, via a centrifuge, the first slurry into a first extract discharge and a first waste discharge.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: September 8, 2020
    Assignee: Heinkel Filtering Systems. Inc.
    Inventors: Alan Ferraro, Bob Edwards
  • Patent number: 10682381
    Abstract: Disclosed is a topical skin composition, and methods for its use, that includes Arctium lappa root extract, Epilobium angustifolium extract, and Cystoseira amentacea/Caespitosa Brachycarpa extract.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: June 16, 2020
    Assignee: Mary Kay Inc.
    Inventors: Michelle Hines, Tiffany Carle
  • Patent number: 10149817
    Abstract: The present invention relates to a topical skin treatment composition comprising Dendranthema indicum extract and, more particularly, to a topical skin treatment composition containing Dendranthema indicum extract which is excellent for the anti-oxidation, anti-aging, whitening, and moisturizing of skin, and also does not cause skin irritation.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: December 11, 2018
    Assignee: Amorepacific Corporation
    Inventors: Kyeong Hwan Hwang, Jun Seong Park, Hyang Tae Choi, Myeong Hun Yeom, Jun Cheol Cho
  • Patent number: 9861573
    Abstract: Disclosed is a composition and methods of its use for whitening skin or evening out skin tone, wherein the composition includes dried navy (haricot)-bean (Phaseolus vulgaris) powder or an aqueous extract thereof.
    Type: Grant
    Filed: August 17, 2015
    Date of Patent: January 9, 2018
    Assignee: Mary Kay Inc.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Patent number: 9782362
    Abstract: The present invention primarily relates to specific uses of a composition containing a roasted extract and xanthohumol for health-promoting purposes.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: October 10, 2017
    Assignee: TA-XAN AG
    Inventors: Werner Back, Achim Zuercher, Sascha Wunderlich
  • Patent number: 9567553
    Abstract: A cleaning composition suspension for use as a liquid anti-microbial cleaner which is non-toxic to the extent that it is safe to ingest includes a base diluted vinegar solution which includes sodium bicarbonate dissolved therein and dried and powdered plant matter suspended therein. The dried and powdered plant matter includes prepared leaves from Guiera Senegalensis, Combretum micranthum, and Combretum glutinosum along with prepared flowers from Hibiscus Sabdariffa. The dried and powdered plant matter may additionally include an anti-caking agent and are prepared in such a manner that they may be stored in and dispensed from a conventional spray bottle similar to conventional cleaning agents.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: February 14, 2017
    Inventor: Omar Mbengue
  • Patent number: 9561198
    Abstract: Disclosed is a topical skin composition, and methods for its use, that includes Arctium lappa root extract, Epilobium angustifolium extract, and Cystoseira amentacea/Caespitosa Brachycarpa extract.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: February 7, 2017
    Assignee: Mary Kay Inc.
    Inventors: Michelle D. Hines, Tiffany Florence
  • Patent number: 9556097
    Abstract: The invention provides a process for the preparation of xanthohumol, wherein a xanthohumol-containing extract is mixed with water, a transition metal salt solution is added to the obtained mixture, and then the obtained xanthohumol precipitate is collected and dried to obtain xanthohumol of the purity higher than 90%.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: January 31, 2017
    Assignee: AXEN BIO GROUP SP. Z O.O.
    Inventor: Mariusz Gagos
  • Patent number: 9555055
    Abstract: Disclosed is a use of albiflorin or a metabolite thereof in preparation of antianxiety and sleep disorder improving drugs or health-care food. Tests prove that albiflorin has significant antianxiety effects and sleep disorder improving effects achieved by prolonging SWS and low the toxic side effects, thus being a safety monomer compound capable of effectively treating anxiety and sleep disorder.
    Type: Grant
    Filed: November 9, 2011
    Date of Patent: January 31, 2017
    Inventor: Zuoguang Zhang
  • Patent number: 9138401
    Abstract: Disclosed is a composition and methods of its use for whitening skin or evening out skin tone, wherein the composition includes dried navy (haricot)-bean (Phaseolus vulgaris) powder or an aqueous extract thereof.
    Type: Grant
    Filed: December 19, 2012
    Date of Patent: September 22, 2015
    Assignee: Mary Kay Inc.
    Inventors: Tiffany Florence, David Gan, Michelle Hines
  • Patent number: 9078838
    Abstract: The present invention relates to cosmetic or dermatological compositions comprising a combination of a cannabis essential oil substantially free of cannabinoids and a helichrysum essential oil, and to their uses thereof, particularly for the care of sensitive or sensitized skin.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: July 14, 2015
    Assignee: LVMH Recherche
    Inventors: Patrice Andre, Isabelle Renimel, Francine Joly
  • Publication number: 20150110758
    Abstract: A treatment protocol for use in the treatment of neurocutaneous syndrome is described and comprises at least one xanthone component, which may comprise at least one mangosteen component, and at least one detoxification component. Additional embodiments comprise at least one herbal component, at least one vitamin component, or a combination thereof. A method of treating a patient having neurocutaneous syndrome is described herein and comprises: providing at least one xanthone component, which may comprise at least one mangosteen component, providing at least one xanthone component, which may comprise at least one mangosteen component, to the patient, and administering the at least one detoxification component to the patient. Additional methods steps may include providing and administering at least one herbal component, providing and administering at least one vitamin component or a combination thereof.
    Type: Application
    Filed: January 5, 2015
    Publication date: April 23, 2015
    Inventor: Omar M. Amin
  • Patent number: 8986758
    Abstract: Disclosed are: a method for extracting a traditional herbal medicine component comprising a process in which a traditional oriental medicine component is steamed together with polished rice; and a composition for an external application to skin comprising an extract which has been extracted by means of the method. The component extracted by means of the extraction method reduces the cytotoxicity of the traditional oriental medicine, is recognized as being effective in alleviating skin irritation, and exhibits an outstanding skin-whitening effect.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: March 24, 2015
    Assignee: Amorepacific Corporation
    Inventors: Dong Hyun Kim, Ji Seong Kim, Hui Kyeung Chang, Duck Hee Kim, Han Kon Kim
  • Patent number: 8980227
    Abstract: The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: March 17, 2015
    Assignee: Kate Somerville Skincare, LLC
    Inventors: Kate Somerville, Fred Khoury
  • Patent number: 8980228
    Abstract: The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three different molecular weights, and about 0.001-5% hyaluronic acid (HA) of molecular weight about 100 kDa or less, packaged in an aerosol spray container.
    Type: Grant
    Filed: March 4, 2013
    Date of Patent: March 17, 2015
    Assignee: Kate Somerville Skincare, LLC
    Inventors: Kate Somerville, Fred Khoury
  • Publication number: 20150050375
    Abstract: Disclosed are a total flavone extract of Abelmoschus Manihot and preparation method thereof. The weight ratio of gossypetin-3?-glucoside, quercetin-3?-glucoside and isoquercetin in the extract is (11-16):(2.5-6):(4-6.5).
    Type: Application
    Filed: September 4, 2012
    Publication date: February 19, 2015
    Inventor: Renmao Tang
  • Publication number: 20150044315
    Abstract: The present invention relates to a plant extract from a low-tetrahydrocannabinol (THC) variety of Cannabis sativa subsp. sativa for the treatment of disease.
    Type: Application
    Filed: October 27, 2014
    Publication date: February 12, 2015
    Inventors: Regina Klaeger, Rudolph Klaeger
  • Publication number: 20150044316
    Abstract: The present invention relates to a method for preparing a purified extract of Lonicera Japonica THUNBERG and the composition comprising the same for preventing and treating sepsis and septic shock. The purified extract of purified extract of Lonicera Japonica THUNBERG potent antisepsis activity in severe sepsis CLP model test, the effect on MODS, and the inhibitory effect on various pro-inflammatory cytokines such as TNF-alpha, IL-1beta, IFN-gamma, HMGB-1 etc, as well as it showed unexpectedly synergistic effect on the treatment of sepsis and septic shock in case of combining with the commercially available anti-septic agent such as broad-spectrum anti-biotic to the person skilled in the art, therefore, it can be useful in treating and preventing the sepsis and septic shock as a medicament and health functional food.
    Type: Application
    Filed: November 1, 2012
    Publication date: February 12, 2015
    Inventors: Sung-Tae Yoon, Jeong Hoon Kim, Bang Ho Lim, Young Mok Kim, Sung Hum Yeon, Hyun Soo Kim, Sun-Mee Lee
  • Patent number: 8916180
    Abstract: A cosmetic treatment system is provided having ingredients that may prevent signs of aging, improve the aesthetic appearance of skin, and promote recovery from environmental stresses. The composition includes natural ingredients, including at least one ingredient or extract from rosemary; at least one ingredient or extract from Centella, Echinacea, Alpinia or mixtures thereof; a DNA repair enzyme; and at least one pharmaceutically or cosmetically acceptable vehicle. The treatment system may further include a patch for applying the cosmetic ingredients and/or a packaging system for holding the components of the cosmetic treatment system.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: December 23, 2014
    Assignee: Access Business Group International LLC
    Inventors: John V. Scimeca, Amy C. Zimmerman, Mark F. Mettler, Akiko Kudo, Yoko Kawasaki
  • Patent number: 8906430
    Abstract: Disclosed is the use of hypericum (Hypericum perforatum L.) tip extracts containing hypericin, of hypericin, to prepare medicinal products and/or food supplements for the treatment of neuropathic pain.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: December 9, 2014
    Assignee: Aboca S.p.A. Societa' Agricola
    Inventors: Valentino Mercati, Franco Francesco Vincieri, Anna Rita Bilia, Carla Ghelardini, Nicoletta Galeotti
  • Publication number: 20140302148
    Abstract: The present invention provides stable, fast-acting liposomal and micelle formulations of cannabinoids that are suitable for pharmaceutical and nutraceutical applications.
    Type: Application
    Filed: June 23, 2014
    Publication date: October 9, 2014
    Inventor: Robert WINNICKI
  • Patent number: 8852658
    Abstract: An anticancer composition containing a flowery portion of elm tree or its extract and a leaf portion of varnish tree or its extract is safe and shows high activity.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: October 7, 2014
    Inventor: Yoshihiro Sekino
  • Publication number: 20140298511
    Abstract: The invention provides compositions and methods for the breeding, production, processing and use of medical cannabis.
    Type: Application
    Filed: March 17, 2014
    Publication date: October 2, 2014
    Applicant: BIOTECH INSTITUTE, LLC
    Inventors: Mark Anthony Lewis, Michael Dane Backes
  • Publication number: 20140242199
    Abstract: Compositions useful for controlling pests are disclosed. In some embodiments, the composition includes a pesticidal natural oil and a polar aromatic solvent. Methods of making and using the compositions are disclosed.
    Type: Application
    Filed: October 4, 2012
    Publication date: August 28, 2014
    Inventors: Karan Manhas, Annett Rozek
  • Patent number: 8808757
    Abstract: An herbal ointment. The herbal ointment may include about 45 weight percent of herb-infused oil, water or alcohol, or any desired combination thereof, about 30 weight percent purified water, about 10 weight percent emulsifier wax, about 5 weight percent menthol, about 3 weight percent dimethyl isosorbide, about 2 weight percent glycerin, about 2 weight percent hydrogenated methyl abietate, about 0.5 weight percent lonicera caprifolium and lonicera japanica extract, about 0.5 weight percent tocopherol, about 0.35 weight percent vanillyl butyl ether, about 0.35 weight percent xanthan gum, about 0.3 weight percent citric acid 50% aqueous solution, and about 0.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: August 19, 2014
    Assignee: Jaxsen's LLC
    Inventors: Michael J. Urschel, Tara L. Urschel, Kraig D. Moore
  • Patent number: 8802161
    Abstract: The invention describes a nutraceutical composition and method for preventing/treating cancer or augmenting chemotherapy in advanced stage malignancies; comprised of [1] tumoricidal herbs; beth root, galbanum, gromwell root, wild yam, balm of gilead bud, frankincense, [2] an antiproliferative herb; speranskia [3] a natural lactic acid dehydrogenase (LDH) inhibitor, 2?,3,4?5,7-pentahydroxyflavone or cinnamon, [4] alkalizing agents: calcium, magnesium, potassium or bicarbonate salts, barley grass, chlorella and spirulina [5] at least one quinone and [6] at least one agent capable of maximizing oxidative mitochondrial function preferably riboflavin, 6,7-Dimethyl-8-(1-D-ribityl)lumazine, ribitol, 5,6-dimethylbenzimidazole, tetrahydrobiopterin and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 30, 2010
    Date of Patent: August 12, 2014
    Assignee: Florida Agricultural and Mechanical University
    Inventors: Elizabeth Anne Mazzio, Karam F Soliman
  • Patent number: 8778420
    Abstract: This invention relates to compositions and applications for a topical skin care composition that includes from about 52 wt % to about 90 wt % Camellia sinensis (green tea) extract; from about 0.5 wt % to about 15 wt % Calendula officinalis extract; from about 0.5 wt % to about 10 wt % Trifolium pratense (red clover blossom) extract; from about 0.1 wt % to about 5 wt % Lavandula angustifolia essential oil in coco-caprylate/caprate; from about 0.5 wt % to about 5 wt % glycerin; an emulsifier component in an amount from about 2 wt % to about 10 wt %; and a preservative component in an amount from about 0.5 wt % to about 3 wt %, wherein the amounts are by total weight of the composition.
    Type: Grant
    Filed: February 26, 2013
    Date of Patent: July 15, 2014
    Inventor: Gary Boyt
  • Patent number: 8778422
    Abstract: In order to provide a composition for the treatment of degenerative joint diseases with an improved efficacy, it is proposed that the composition comprises collagen hydrolysate and rosehip powder and/or extract, wherein the weight ratio of collagen hydrolysate to rosehip powder and/or extract, in each case in relation to dry mass, lies in the range of approximately 2:1 to approximately 100:1.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: July 15, 2014
    Assignee: Gelita AG
    Inventor: Steffen Oesser
  • Patent number: 8765194
    Abstract: This invention replaces the practice of utilizing synthesized salicin compounds for use as anti-inflammatory components in topical pain relief compositions through the use of naturally occurring salicin in the form of Salix alba (white willow bark) botanicals. This invention is a compound of naturally occurring botanicals identified in the Natural Pharmacopeia as individually exhibiting anti-inflammatory and/or analgesic properties.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: July 1, 2014
    Inventors: Michelle Mills, Michael Hutsell
  • Patent number: 8758837
    Abstract: A method for removing pests from harvested vegetables has steps of extracting a first portion of harvested vegetables to obtain a vegetable cleanser, and cleaning a second portion of harvested vegetables with the vegetable cleanser, such that pests residing on the second portion of harvested vegetables are removed from the second portion of harvested vegetables, wherein the first portion of harvested vegetables and the second portion of harvested vegetables independently contain vegetables selected from the group consisting of vegetables belonging to the families of Cruciferae, Compositae, Chenopodiaceae and Amaranthaceae. The aforementioned method is effective at removing pests from harvested vegetables and satisfies urgent needs to reduce use of chemical pesticides.
    Type: Grant
    Filed: July 2, 2009
    Date of Patent: June 24, 2014
    Assignee: Food Industry Research & Development Institute
    Inventors: Tin-Yin Liu, Yi-Kai Wang, Mei-Ling Lu
  • Publication number: 20140147394
    Abstract: The present invention provides a non-parenteral and non-ocular herbal synergistic detoxifier composition effective for blood purification, blood detoxification and in the treatment and management of disorders related to accumulation of toxins in the body having synergistic effect of its components in specific ratio, better bio availability wherein the amount of dose administered is remarkably low. The formulation of synergistic herbal composition has better patient compliance in the terms of palatability, ease of administration and is formulated in the form of syrup, lozenges/candies/jujubs/mouth freshener, sub-lingual tablets or chewable tablets. The present invention also provides a method of preparation of this formulation.
    Type: Application
    Filed: October 25, 2011
    Publication date: May 29, 2014
    Inventor: Manu Chaudhary
  • Patent number: 8734869
    Abstract: Pest control compositions, blends, and formulations are disclosed. The blends contain, in a synergistic combinations, at least two ingredients such as Lilac Flower Oil, D-Limonene, Thyme Oil, Lime Oil, Black Seed Oil, Wintergreen Oil, Linalool, Tetrahydrolinalool, Vanillin, Isopropyl myristate, Piperonal (aldehyde), Geraniol, Geraniol 60, Triethyl Citrate, and Methyl Salicylate.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: May 27, 2014
    Assignee: TyraTech, Inc.
    Inventor: Essam Enan
  • Publication number: 20140120043
    Abstract: Disclosed is a stable cosmetic composition having a syrupy texture while not being sticky, and translucent (or even transparent) appearance. Further disclosed is a method of preparation of such composition, as well as a method of its use.
    Type: Application
    Filed: June 15, 2012
    Publication date: May 1, 2014
    Applicant: Chanel Parfums Beaute
    Inventors: Sophie Foucault, Veronique Kowandy, Veronique Trouillet
  • Patent number: 8697149
    Abstract: The invention provides extracts and preparations based on the species Tulbaghia violacea (Harv.) (wild garlic), which elicits a significant antimicrobial, preferably antifungal activity in vitro and in vivo, even under field and glasshouse conditions. Moreover, these extracts deriving from the soil parts as well as of the aerial parts of the plant elicit a significant bio-stimulatory activity, expressed, above all, by an increased growth metabolism supporting seed growth. Furthermore, combined extracts or preparations from Tulbaghia violacea and species of the genus Agapanthus show a higher antifungal and bio-stimulatory efficacy as compared to the extracts or preparations of the single species, indicating that synergism is participated in the involved biological processes.
    Type: Grant
    Filed: June 24, 2006
    Date of Patent: April 15, 2014
    Assignees: Agrarforum AG, Agrarforum SA (Pty) Ltd.
    Inventor: Johannes Christiaan Pretorius
  • Patent number: 8697099
    Abstract: A cosmetic treatment system is provided having ingredients that may prevent signs of aging, improve the aesthetic appearance of skin, and promote recovery from environmental stresses. The composition includes natural ingredients, including at least one ingredient or extract from rosemary; at least one ingredient or extract from Centella, Echinacea, Alpinia or mixtures thereof; a DNA repair enzyme; and at least one pharmaceutically or cosmetically acceptable vehicle. The treatment system may further include a patch for applying the cosmetic ingredients and/or a packaging system for holding the components of the cosmetic treatment system.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: April 15, 2014
    Assignee: Access Business Group International LLC
    Inventors: John V. Scimeca, Amy C. Zimmerman, Mark F. Mettler, Akiko Kudo, Yoko Kawasaki
  • Patent number: 8673278
    Abstract: A bruise amelioration composition that can be applied for one hour to an affected site, such as a bruise, contusion or blister, in the form of a gel, liquid or adhesive bandage. The composition includes at least 40% by weight of glycerin and at least 2% by weight of primrose oil. Preferably, the composition includes a fragrance, such as peach oil and marjoram and 1% to 10% by weight of vitamins A, C, D, E and K.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: March 18, 2014
    Assignee: Dr. Holmquist Healthcare, L.L.C.
    Inventors: Bruce A. Cranner, Anne-Marie T. Karp
  • Publication number: 20140072664
    Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
    Type: Application
    Filed: May 17, 2012
    Publication date: March 13, 2014
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jae Wha Kim, Kyung Seop Ahn, Ho Bum Kang, Sei Ryang Oh, Jae Jong Go, Joo Heon Kim, Jang Mi Sun, Jae Sung Song, Hyun Woo Oh, Da Jung Ji
  • Patent number: 8658226
    Abstract: The present invention provides an agent having anti-Helicobacter pylori activity that is effective for the treatment, prevention or improvement of diseases associated with Helicobacter pylori and contains as an active ingredient thereof an extract of a plant belonging to the Labiatae family. The agent having anti-Helicobacter pylori activity of the present invention has superior heat stability and allows the obtaining of elimination effects in a short period of time.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: February 25, 2014
    Assignees: Japan Royal Jelly Co., Ltd., University of the Ryukyus
    Inventors: Yoshiya Sato, Hiromu Toma, Hironori Iwasaki, Kikuji Yamaguchi
  • Patent number: 8652545
    Abstract: The object of the present invention is to provide an all-natural dietary supplement formulation that may be beneficial to the management of behavioral and neurological symptoms associated with autism spectrum disorders; symptoms that may not be effectively improved by conventional drug treatment and behavioral therapy alone.
    Type: Grant
    Filed: February 12, 2009
    Date of Patent: February 18, 2014
    Assignee: Reverta Health Solutions LLC
    Inventor: Bart Nieuwenhuijsen
  • Patent number: 8637092
    Abstract: The present invention relates to methods for preparing a pharmaceutical composition for treating diabetes mellitus and the pharmaceutical composition prepared by the methods. The pharmaceutical composition of the present invention comprises extracts of the following crude drugs: 5-40 weight parts of Radix Trichosanthis (Tianhuafen), 10-30 weight parts of Radix Bupleuri (Chaihu), 3-15 weight parts of Fructus Aurantii Immaturus (Zhishi), 1-6 weight parts of Radix et Rhizoma Rhei (Dahuang), 1-12 weight parts of Rhizoma Pinelliae (Banxia), 3-15 weight parts of Radix Scutellariae (Huangqin), 1-12 weight parts of Rhizoma Coptidis (Huanglian), 3-15 weight parts of Radix Paeoniae Alba (Baishao) and 5-20 weight parts of Fructus Mume (Wumei), and optionally comprises pharmaceutically acceptable excipient. Also, the pharmaceutical composition of the present invention can further comprise Fructus Crataegi (Shanzha). Additionally, the present invention discloses four methods for preparing the pharmaceutical composition.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: January 28, 2014
    Assignee: Tasly Pharmaceutical Group Co., Ltd.
    Inventors: Xiaolin Tong, Yonghong Zhu, Shuiping Zhou, Xiuhui E, Shuangming Wang, Zhongting Xia
  • Patent number: 8637099
    Abstract: The present invention relates to the use of fruit extract from Vitex agnus castus and/or one or more isolated and/or synthetically prepared bicylic diterpenes from Vitex agnus castus for the preparation of a medicament for the treatment of movement disorders. In particular, the invention is directed to the preparation of medicaments for treating Parkinson disease (PD), Periodic Limb Movement disorder (PLMD) and Restless Leg Syndrome (RLS), Huntington disease (HD) and Essential Tremor (ET), preferably familiar ET. Furthermore, the invention concerns a pharmaceutical composition comprising a fruit extract from Vitex agnus castus and/or one or more isolated and/or synthetically prepared bicylic diterpenes from Vitex agnus castus and at least one pharmaceutically compatible dopamine D2 and/or D3 receptor agonist.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: January 28, 2014
    Assignee: Max Zeller Sohne AG
    Inventor: Axel Brattström
  • Patent number: 8628783
    Abstract: A method for reducing the occurrence of wrinkles in skin caused by aging by promoting the growth of fibroblasts, which have a declined cellular proliferative potential due to aging or adverse affects from ultraviolet light or active oxygen. The method includes the steps of providing an agent that contains a yeast extract and a safflower extract as effective constituents, and applying the agent to skin to promote the growth of fibroblasts.
    Type: Grant
    Filed: August 24, 2012
    Date of Patent: January 14, 2014
    Assignee: Shiseido Company, Ltd.
    Inventors: Masato Iino, Satoshi Amano
  • Patent number: 8597701
    Abstract: Disclosed herein is a method for treating an androgen-stimulated disease in a subject in need thereof by administering to the subject a composition containing an effective amount of an inhibitor of I?B kinase subunit ? activity. The composition can also be administered to a subject at high risk for prostate cancer as a method for reducing the subject's risk thereof. A further method relates to identifying a modulator of transcriptional activity regulated by I?B kinase subunit ?. Still another method relates to determining the I?B kinase subunit ?-regulated transcriptional activity regulated by in a non-human mammalian test subject.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: December 3, 2013
    Assignee: Academia Sinica
    Inventor: Pei-Wen Hsiao
  • Publication number: 20130309338
    Abstract: An object of the present invention is to provide a water-solubilizing preparation that is obtained by convenient steps without use of a special apparatus such as a high-pressure homogenizer, does not impair the original properties of a water-based material even after being added to the material, has high dispersibility and transparency and excellent heat resistance and acid resistance, and can maintain stability. The water-solubilizing preparation of the present invention is a biologically active substance-containing water-solubilizing preparation comprising 1 to 50% by weight of an oily ingredient (A) containing a biologically active substance and oil, 10 to 98% by weight of a polyglycerin fatty acid ester (B) having an HLB value of 12.5 or larger, and 1 to 40% by weight of a surfactant (C) having an HLB value of 7 to 11.8.
    Type: Application
    Filed: January 31, 2012
    Publication date: November 21, 2013
    Inventors: Takao Yamaguchi, Toshinori Ikehara
  • Publication number: 20130302279
    Abstract: The present invention relates to a novel use of naturally occurring plants, mushroom, extracts thereof that exhibit properties as HCV NS5B polymerase inhibitors.
    Type: Application
    Filed: April 22, 2013
    Publication date: November 14, 2013
    Applicants: University of Medicine & Dentistry of New Jersey, Rutgers, The State University of New Jersey
    Inventors: James E. Simon, Qingli Wu, Neerja Kaushik-Basu
  • Publication number: 20130302419
    Abstract: The present invention relates to the use of a plant extract obtained from at least one plant of the Anacardiaceae family, for the preparation of a pharmaceutical composition used as a new herbal medicine for the prophylaxis and/or treatment of disorders associated with the digestive tract, and the relief of symptoms associated with these disorders. Additionally, through the scope of the present invention, the substances isolated from said extract also consist of the active ingredients of pharmaceutical compositions. A third objective of the invention is the use of said pharmaceutical compositions in the preparation of the class of herbal medicines for the prophylaxis and/or treatment of disorders associated with the digestive tract, in different stages, with posology and daily dosing.
    Type: Application
    Filed: August 3, 2011
    Publication date: November 14, 2013
    Applicant: HEBRON FARMACEUTICA PESQUISA, DESENVOLVIMENTO E INOVACAO TECNOLOGICA LTDA
    Inventors: Avaniel Marinho Da Silva, Tulio Flávio Accioly Lima E Moura, Severino Barbosa Dos Santos
  • Publication number: 20130287873
    Abstract: The disclosure provides a pharmaceutical composition for promoting wound healing, including an effective amount of a Sambucus plant or an Isatis plant as an active ingredient for promoting wound healing; and a pharmaceutically acceptable carrier or medium, wherein the Sambucus plant is Sambucus formosana Nakai, and the Isatis plant is Isatis indigotica Fort.
    Type: Application
    Filed: April 26, 2013
    Publication date: October 31, 2013
    Applicant: Industrial Technology Research Institute
    Inventors: Pei-Yi TSAI, Hsiang-Wen TSENG, Yen-Chun CHEN, Hui-Chun HSU, Yi-Hung WEN, Chun-Chung WANG, Shu-Jiau CHIOU