Carbohydrate Is Cellulose Or Derivative Thereof Patents (Class 435/179)
  • Patent number: 9926648
    Abstract: Processes for making fibrous structures and more particularly processes for making fibrous structures comprising filaments are provided.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: March 27, 2018
    Assignee: The Procter & Gamble Company
    Inventors: Steven Lee Barnholtz, Paul Dennis Trokhan, Michael Donald Suer, Douglas Jay Barkey, Jonathan Paul Brennan, Ronald Thomas Gorley
  • Patent number: 9714945
    Abstract: The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: July 25, 2017
    Assignee: MILTENYI BIOTEC GMBH
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Elmar Niklas Neuschäfer, Martin Biehl, Eiad Kabaha, Jürgen Schulz
  • Patent number: 9540608
    Abstract: The present invention is a bacteria and nutrient delivery composition containing bran. The subject composition is preferably made in the form of a tablet that is structurally stable without being excessively hard. The tablets preferably have a configuration that reduces the likelihood of premature shearing in tableting presses or jamming in feeder devices for biomass generators. Methods of manufacturing the bacterial delivery composition in a structurally stable form that maintains bacterial viability are also provided.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: January 10, 2017
    Assignee: NCH CORPORATION
    Inventors: Judith G. Pruitt, Robert Clarence Pearce, III, John Ray Roheim
  • Publication number: 20150010980
    Abstract: Disclosed is a composition for embedded three-dimensional microbial culture, the composition including nanofibrillar cellulose and at least one nutrient source. Also disclosed is a method for the manufacture of a composition for embedded three-dimensional microbial culture, the method including the steps of providing nanofibrillar cellulose, mixing the nanofibrillar cellulose with water and at least one nutrient source and optional additives to obtain a mixture, and optionally drying the mixture.
    Type: Application
    Filed: December 18, 2012
    Publication date: January 8, 2015
    Applicant: UPM-KYMMENE CORPORATION
    Inventors: Marko Lauraeus, Antti Laukkanen
  • Patent number: 8911980
    Abstract: The present invention provides a method for producing a ground product of a lipase powder composition comprising an immobilized lipase in which a lipase derived from Thermomyces sp. is immobilized to a silica carrier and a hydrophilic powder other than a silica carrier, the method comprising the steps of wetting the hydrophilic powder with oil; separating the hydrophilic powder wetted with oil from the oil to obtain an oil-containing hydrophilic powder; mixing the oil-containing hydrophilic powder and the immobilized lipase at a ratio of 0.45:1 to 0.85:1 based on mass of the hydrophilic powder and the immobilized lipase before oil wetting; and grinding the obtained mixture, the steps being conducted in the above order.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: December 16, 2014
    Assignee: The Nisshin Oillio Group, Ltd.
    Inventors: Junko Suzuki, Yoshie Yamauchi, Yuko Toyama, Satoshi Negishi
  • Patent number: 8871283
    Abstract: The present invention relates to a method of making a sorbent, comprising the steeps of crushing seed husks, acid hydrolysis with extraction of water-soluble ballast substances and formation of the target composition of lignin, cellulose and melanin, water rinsing and drying, wherein the acid hydrolysis is made with an 0.1-36% acid solution during 0.3-4.5 hours in the boiling mode under pressure in the range 0.1-0.7 MPa, rinsing is made with water and/or a 0.1-1.0% alkali solution and then softened water, and the product is subsequently dried. The sorbent comprises a porous multilevel matrix on the basis of lignin, cellulose and melanin. The invention further discloses the sorbent and its uses as for prophylaxis and treatment of toxicoses, free-radical pathologies, diarrhea syndromes which are caused by ecotoxicants, viral and bacterial infections, for prophylactic and treatment of animal diseases caused by mycotoxins, pesticides, bad-quality forages in all kinds of animals.
    Type: Grant
    Filed: July 10, 2007
    Date of Patent: October 28, 2014
    Assignee: Gosudarstvennoe Nauchnoe Uchrezhdenie “Institut Phyziki Im. B.I.: Stepanova” Nacionalnojj Acadzhemii Nauk Belarusi
    Inventors: Viktoria Alexeevna Lapina, Alexander Evgenievich Dontsov, Igor Viktorovich Nasonov
  • Publication number: 20140224721
    Abstract: A device for reducing the content of polluting and/or unwanted substances in water, including a support made of polymeric material for a catalyst of the reaction of degradation of inorganic salts into gaseous substances; the catalyst, intended to reduce the energy required for the activation of the reaction and to accelerate its course, is an enzyme preferably selected from the group of lyases, and even more preferably selected from the subgroup of carbonic anhydrases. The inorganic are being carbonates, and/or hydrogen carbonates of calcium and/or magnesium, the reaction being the reaction of decarboxylation and acting for the conversion of inorganic salts into carbon dioxide and water according to the following reaction: HCO3?+H+H2O+CO2.
    Type: Application
    Filed: September 5, 2012
    Publication date: August 14, 2014
    Applicant: Arhimede R&D S.R.L.
    Inventor: Lucio Panizza
  • Patent number: 8790725
    Abstract: This invention relates to compositions and methods for improving water quality by enhancing natural bacterial processes and altering environmental conditions in situ. This is achieved by the manufacture and use of granules or tablets composed of the inventive formulations.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: July 29, 2014
    Assignee: Aqua Dynamic Solutions, LLC
    Inventor: John W. Dituro
  • Patent number: 8715639
    Abstract: The present invention relates to the field of bacteriology. In particular, the invention relates to compositions of probiotic microbes and methods for making and using such compositions, e.g. in the treatment and prevention of catheter associated urinary tract infections.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: May 6, 2014
    Assignee: Conjugon, Inc.
    Inventors: Hideki Suzuki, Salvatore Braico
  • Patent number: 8691974
    Abstract: A novel BC fermentation technique for controlling 3D shape, thickness and architecture of the entangled cellulose nano-fibril network is presented. The resultant nano-cellulose based structures are useful as biomedical implants and devices, are useful for tissue engineering and regenerative medicine, and for health care products. More particularly, embodiments of the present invention relate to systems and methods for the production and control of 3-D architecture and morphology of nano-cellulose biomaterials produced by bacteria using any biofabrication process, including the novel 3-D Bioprinting processes disclosed. Representative processes according to the invention involve control of the rate of production of biomaterial by bacteria achieved by meticulous control of the addition of fermentation media using a microfluidic system. In exemplary embodiments, the bacteria gradually grew up along the printed alginate structure that had been placed into the culture, incorporating it.
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: April 8, 2014
    Assignee: Virginia Tech Intellectual Properties, Inc.
    Inventors: Paul Gatenholm, Henrik Backdahl, Theodore Jon Tzavaras, Rafael V. Davalos, Michael B. Sano
  • Patent number: 8673294
    Abstract: An immunoisolation patch system, and particularly a patch system comprising multiple immunoisolation microcapsules, each encapsulating biological material such as cells for transplantation, which can be used in the prophylactic and therapeutic treatment of disease in large animals and humans without the need for immunosuppression.
    Type: Grant
    Filed: April 23, 2009
    Date of Patent: March 18, 2014
    Assignee: Vanderbilt University
    Inventor: Taylor G. Wang
  • Publication number: 20140017761
    Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain including: a moiety R that is chemically coupled to the substrate, the moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker including at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.
    Type: Application
    Filed: September 18, 2013
    Publication date: January 16, 2014
    Applicant: TEMASEK POLYTECHNIC
    Inventors: Christian Gert BLUCHEL, Yanmei WANG
  • Publication number: 20140010790
    Abstract: The present invention relates material based on microbial cellulose that is useful in culturing and transferring cells as well as delivering drugs. The material comprises cellulose nanofibers and/or derivatives thereof, based on microbial cellulose, wherein the cellulose nanofibers are in a form of a hydrogel or membrane. The invention also provides methods for producing these materials and compositions and uses thereof.
    Type: Application
    Filed: October 26, 2011
    Publication date: January 9, 2014
    Applicant: UPM-KYMMENE CORPORATION
    Inventors: Marjo Yliperttula, Patrick Laurén, Madhushree Bhattacharya, Yanru Lou, Antti Loukkanen
  • Publication number: 20130344036
    Abstract: The present invention relates material that is useful in culturing and transferring cells as well as delivering cells. The material comprises plant derived cellulose nanofibers or derivatives thereof, wherein the cellulose nanofibers are in a form of a hydrogel or membrane. The invention also provides methods for producing these materials and compositions and uses thereof.
    Type: Application
    Filed: October 26, 2011
    Publication date: December 26, 2013
    Applicant: UPM-KYMMENE CORPORATION
    Inventors: Marjo Yliperttula, Patrick Laurén, Madhushree Bhattacharya, Yanru Lou, Antti Laukkanen
  • Publication number: 20130337529
    Abstract: A method for determining the effect of a plurality of culture conditions on a cell, comprising the steps of: a) providing a first set of groups of cell units each comprising one or more cells, and exposing said groups to desired culture conditions; (b) pooling two or more of said groups to form at least one second pool; (c) subdividing the second pool to create a further set of groups of cell units; (d) exposing said further groups to desired culture conditions; (e) optionally, repeating steps (b)-(d) iteratively as required; and (f) optionally assessing the effect on a given cell unit of the culture conditions to which it has been exposed.
    Type: Application
    Filed: April 5, 2013
    Publication date: December 19, 2013
    Inventor: Yen Choo
  • Publication number: 20130316431
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked organophosphate-degrading enzyme having a support material which includes a biomass material and/or a polymeric material. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized organophosphate hydrolase enzyme and enzyme materials.
    Type: Application
    Filed: November 13, 2012
    Publication date: November 28, 2013
    Inventors: Augustine A. DiNovo, Dominic P. DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Publication number: 20130309746
    Abstract: The present application discloses immobilized enzymes and immobilized enzyme materials comprising a crosslinked enzyme having a support material which includes a biomass material different than the biomass used to initially derive the enzyme. Optionally, the immobilized enzyme further includes a polymeric material and/or the biomass which was used to initially derive the enzyme. The resulting immobilized enzyme materials may be biodegradable. The present application also discloses methods of making and using the disclosed immobilized enzyme materials.
    Type: Application
    Filed: November 13, 2012
    Publication date: November 21, 2013
    Inventors: Augustine A. DiNovo, Dominic P. DiNovo, David A. Schofield, Matthew F. Smiechowski, Francis H. Verhoff
  • Patent number: 8584892
    Abstract: A packet of an enzyme and/or enzyme producing bacteria is contained within the core of a roll of toilet tissue or similar paper product wound on a core. The packet has a cover that dissolves or disintegrates on contact with water and disperses its contents into the aqueous waste stream. The packet may contain a mixture of bacterial cultures that produce enzymes to attack the greasy or fatty components of the waste stream. An additional article such as a sample of a liquid or creme personal care product may also be contained within the tissue paper core.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: November 19, 2013
    Inventor: Joseph R. Lira
  • Patent number: 8569062
    Abstract: The present invention relates to a cryogel which contains a polyol selected from polyvinyl alcohol or galactomannan and a co-polymer of Formula I: The cryogel is formed by mixing the monomers of the co-polymer of Formula I at a temperature of less about 5 degrees C. with the polyol and a free radical initiator in an aqueous solution and polymerizing the solution to form the cryogel. The cryogel is used for culturing cells and can be decomposed by contact with a monosaccharide.
    Type: Grant
    Filed: August 8, 2011
    Date of Patent: October 29, 2013
    Assignee: Indian Institute of Technology Kanpur
    Inventor: Ashok Kumar
  • Publication number: 20130224799
    Abstract: A method is disclosed for improved isothermal amplification of nucleic acids comprising the step of release of an essential component from a matrix under predetermined conditions. Furthermore, the invention relates to a kit comprising mesophilic enzyme and a matrix with embedded essential components for isothermal amplification. A composition comprising a matrix and a mesophilic enzyme and a method for embedding a mesophilic enzyme are disclosed as well.
    Type: Application
    Filed: August 9, 2011
    Publication date: August 29, 2013
    Applicant: QIAGEN GMBH
    Inventor: Christian Korfhage
  • Patent number: 8518683
    Abstract: Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials, to produce ethanol and/or butanol, e.g., by fermentation.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: August 27, 2013
    Assignee: Xyleco, Inc.
    Inventors: Marshall Medoff, Thomas Craig Masterman
  • Publication number: 20130211143
    Abstract: The present invention relates to a cell retaining matrix (CRB) for producing solvents and alcohols and an apparatus comprising said bio-column. The invention also relates to the method for producing solvents and alcohols by using said cell retaining matrix (CRB). Said cell retaining biomatrix (CRB cellulosic fibers, selected from the group consisting wood cellulosic fibers, pulp cellulosic fibers, vegetable cellulosic fibers, such as mechanical pulp, dissolving pulp, lignocellulosic fibers, and cellulosic fibers originated from vegetable peels, and at microbes, which have been immobilized into said cellulosic fibers, and which can save their biological activity in cell retaining biomatrix (CRB).
    Type: Application
    Filed: July 8, 2011
    Publication date: August 15, 2013
    Applicant: AALTO UNIVERSITY FOUNDATION
    Inventor: Tom Granstrom
  • Publication number: 20130210111
    Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain including: a moiety R that is chemically coupled to the substrate, the moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker including at least one nucleophilic group.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 15, 2013
    Applicant: TEMASEK POLYTECHNIC
    Inventors: Christian Gert BLUCHEL, Yanmei WANG
  • Patent number: 8501207
    Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material. More than one fungus and substrate can be used in combination.
    Type: Grant
    Filed: April 18, 2011
    Date of Patent: August 6, 2013
    Inventor: Paul Stamets
  • Publication number: 20130172705
    Abstract: The present invention is broadly concerned with the crafting and manufacturability of an implantable enzymatic-based sensor characterized by a small size, optimum geometry, linearity of response over the concentration range of interest, extended shelf-life, selectivity for the analyte in question, and the ability to exclude bioactive interferents. More particularly, it is preferably concerned with a general approach to optimize the performance of the biorecognition elements required to produce biosensors of the type designed to provide, and in conjunction with a suitable signal processing unit, a current which is proportional to the concentration of the analyte of interest. The biosensors described herein may be implanted in vivo, including intra-cerebral, sub-cutaneous, intra-muscular, inter-peritoneal oral, serum, and vascular implantation, the majority of which may act as a surrogate for systemic monitoring and used to monitor analytes of interest in real-time.
    Type: Application
    Filed: September 12, 2011
    Publication date: July 4, 2013
    Applicant: PINNACLE TECHNOLOGY, INC.
    Inventors: Peter A. Petillo, Daniel V. Aillon, Brian S. Barrett
  • Publication number: 20130130284
    Abstract: Disclosed is a composite of enzyme and fiber matrix with three-dimensional structure. The composite of enzyme and fiber matrix with three-dimensional structure includes a significantly large amount of an enzyme loaded in and immobilized in/onto a matrix when compared to conventional composites. In addition, the immobilized enzyme is prevented from leaching from the matrix when an external impact is applied to the composite of enzyme and fiber matrix with three-dimensional structure. Therefore, the stability of the composite of enzyme and fiber matrix with three-dimensional structure of the present invention is maintained even after a long period passes since a remarkably great amount of enzymes compared with a known composite can be supported and immobilized to a matrix, and the immobilized enzyme is not easily released by an external impact.
    Type: Application
    Filed: April 19, 2011
    Publication date: May 23, 2013
    Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Jungbae Kim, Hyeong-Seok Kim
  • Publication number: 20130048559
    Abstract: A substrate having compounds disposed thereon for immobilizing a functional molecule, each compound having a chain comprising: a moiety R that is chemically coupled to the substrate, said moiety R being selected from the group consisting of an ether, ester, carbonyl, carbonate ester, thioether, disulfide, sulfinyl, sulfonyl, and carbonothioyl; and an epoxide-containing moiety that is coupled to the moiety R by a linker comprising at least one nucleophilic group. Methods of preparing the substrate and use of the substrate are also disclosed.
    Type: Application
    Filed: February 18, 2011
    Publication date: February 28, 2013
    Applicant: TEMASEK POLYTECHNIC
    Inventors: Christian Bluchel, Yanmei Wang
  • Publication number: 20130018112
    Abstract: A cellulose aerogel comprises a plurality of cellulose nanoparticles. The cellulose nanoparticles preferably comprise at least 50% or 80% cellulose nanocrystals by weight of cellulose nanoparticles, and the cellulose nanoparticle aerogel preferably has a density of from 0.001 to 0.2 g/cm3 or from 0.2 to 1.59 g/cm3 The cellulose nanoparticle aerogel typically has an average pore diameter of less than 100 nmm and the cellulose nanoparticles may comprise anionic and/or cationic surface groups.
    Type: Application
    Filed: September 14, 2010
    Publication date: January 17, 2013
    Applicant: University of Nottingham
    Inventors: Wim Albert Wilfried Irene Thielemans, Rebecca Davies
  • Publication number: 20120255901
    Abstract: A device for the treatment of waste material in a waste water collection system includes an inner core and an outer portion partially surrounding the inner core such that at least one surface of the inner core is exposed. The inner core has a greater water solubility than the outer portion.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 11, 2012
    Applicant: UNITED LABORATORIES, INC.
    Inventors: Vincent J. Thorgersen, John H. Bacon, Eric D. Frazier
  • Publication number: 20120202261
    Abstract: This disclosure relates generally to methods, apparatuses, and cellular compositions and cellular products that use a unique trophoblast-containing 3D matrix as a compartmental chamber for growing embryoid bodies that can be induced to differentiate into organ-specific cell types.
    Type: Application
    Filed: February 3, 2011
    Publication date: August 9, 2012
    Inventor: Yansong Gu
  • Publication number: 20120190078
    Abstract: A novel BC fermentation technique for controlling 3D shape, thickness and architecture of the entangled cellulose nano-fibril network is presented. The resultant nano-cellulose based structures are useful as biomedical implants and devices, are useful for tissue engineering and regenerative medicine, and for health care products. More particularly, embodiments of the present invention relate to systems and methods for the production and control of 3-D architecture and morphology of nano-cellulose biomaterials produced by bacteria using any biofabrication process, including the novel 3-D Bioprinting processes disclosed. Representative processes according to the invention involve control of the rate of production of biomaterial by bacteria achieved by meticulous control of the addition of fermentation media using a microfluidic system. In exemplary embodiments, the bacteria gradually grew up along the printed alginate structure that had been placed into the culture, incorporating it.
    Type: Application
    Filed: September 28, 2010
    Publication date: July 26, 2012
    Inventors: Paul Gatenholm, Henrik Backdahl, Theodore Jon Tzavaras, Rafael V. Davalos, Michael B. Sano
  • Publication number: 20120122691
    Abstract: Disclosed are composites that comprise regenerated cellulose, a first active substance, a second active substance, and a linker. Methods for preparing the composites that involve the use of ionic liquids are also disclosed. Articles prepared from the disclosed composites and methods of using them are further disclosed.
    Type: Application
    Filed: June 5, 2007
    Publication date: May 17, 2012
    Inventors: Daniel T. Daly, Scott K. Spear, Megan B. Turner, Whitney Lauren Hough, Robin D. Rogers
  • Publication number: 20120107900
    Abstract: The present invention provides electrospun polymer fibers comprising bacteria-containing hydrogel particles. Bacteria-containing hydrogel particles are produced by crosslinking water-soluble polymers to form hydrogels and mixing them with a bacteria suspension. The crosslinking is suitable to be carried out either chemically before the addition of the bacteria suspension or physically before or after this addition. Subsequently, these hydrogel particles are electrospun together with an electrospinnable polymer solution to form fibers or fibre non-wovens. The bacteria which are located in these hydrogel particles or in the electrospun polymer fibers comprising these particles, respectively, are capable of surviving for a long period (several months) without the supply of water or cell-culture media and are simultaneously protected against the effect of solvents, for example alcohols, acetone, chlorinated hydrocarbons, ethers and toluene, which would otherwise kill said bacteria.
    Type: Application
    Filed: December 18, 2009
    Publication date: May 3, 2012
    Applicant: Philipps-Universitat Marburg
    Inventors: Andreas Greiner, Seema Agarwal, Marco Gensheimer
  • Patent number: 8124387
    Abstract: The invention relates to a process for the production of optically active Citronellal by enzymatic reduction of Citral with a reductase from Zymomonas mobilis.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: February 28, 2012
    Assignee: BASF SE
    Inventors: Rainer Stuermer, Thomas Friedrich, Andre Mueller, Bernhard Hauer, Bettina Rosche
  • Publication number: 20110281321
    Abstract: Methods and systems for effecting an environmental change by providing an effector composition that includes lignocellulosic particles with at least one absorbed microorganism species, wherein the lignocellulosic particles are preferably kenaf particles. The method steps include mixing at least one microorganism species with kenaf particles to form an effector composition and then dispersing the effector composition in the environment.
    Type: Application
    Filed: May 11, 2011
    Publication date: November 17, 2011
    Inventor: Paul SKILLICORN
  • Patent number: 8053216
    Abstract: A new method to produce formulations of bacterial cellulose that exhibit improved viscosity-modifying properties particularly with low energy applied to effectuate viscosity changes therewith is provided. Such a method includes the novel co-precipitation with a water soluble co-agent that permits precipitation in the presence of excess alcohol to form an insoluble fiber that can than be utilized as a thickener or suspension aid without the need to introduce high energy mixing. Such bacterial cellulose properties have been available in the past but only through highly labor and energy intensive processes. Such an inventive method as now proposed thus provides a bacterial cellulose-containing formulation that exhibits not only properties that are as effective as those for previous bacterial celluloses, but, in some ways, improvements to such previous types. Certain end-use compositions and applications including these novel bacterial cellulose-containing formulations are also encompassed within this invention.
    Type: Grant
    Filed: May 23, 2005
    Date of Patent: November 8, 2011
    Assignee: CP Kelco U.S., Inc.
    Inventors: Zhi-Fa Yang, Neil A. Morrison, Todd A. Talashek, David F. Brinkmann, Don DiMasi, You Lung Chen
  • Publication number: 20110171713
    Abstract: There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.
    Type: Application
    Filed: June 22, 2009
    Publication date: July 14, 2011
    Inventors: Christian Gert Bluchel, Yanmei Wang, Kim Cheng Tan
  • Patent number: 7951388
    Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material. More than one fungus and substrate can be used in combination.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: May 31, 2011
    Inventor: Paul Stamets
  • Patent number: 7951389
    Abstract: The present invention utilizes extracts of the pre-sporulation (preconidial) mycelial stage of entomopathogenic fungi as insect attractants and/or pathogens. The fungus can be cultivated on grain, wood, agricultural wastes or other cellulosic material. More than one fungus and substrate can be used in combination.
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: May 31, 2011
    Inventor: Paul Stamets
  • Publication number: 20110117596
    Abstract: A composite sorbent material is disclosed which comprises A) a housing of a dense, insoluble material having openings therein and B) a porous polymer gel housed within said housing, said housing being provided with openings therein for fluid communication between said porous monolithic polymer gel and the surroundings, and said porous monolithic polymer gel occupying the inner space of said housing and being kept on place within said housing by mechanical means. Processes for the preparation of composite sorbent materials by cryoprecipitation are also disclosed as well as the use of the composite sorbent material according to the invention e.g. for the removal of pollutants from gases or liquids, for the enrichment or separation of molecules and for cell culture.
    Type: Application
    Filed: March 20, 2007
    Publication date: May 19, 2011
    Inventors: Bo Mattiasson, Fatima Plieva
  • Publication number: 20110045557
    Abstract: The invention relates a novel hybrid carbonic anhydrase catalyst with the potential to contribute significantly to meeting targeted reductions in greenhouse gas emissions. In a preferred embodiment of the present invention at least a portion of a cellulose binding domain (CBD) of a protein is fused to another protein, carbonic anhydrase, (CA) to create a new multi-functional protein which can bind tightly to cellulose while maintaining its native catalytic ability to process CO2. The resulting CA-CBD hybrid polypeptide can be immobilized to a cellulose support and used to cost-effectively capture CO2 from gas streams and other CO2-rich environs.
    Type: Application
    Filed: July 27, 2007
    Publication date: February 24, 2011
    Inventors: Mohammed Ataai, Robert Dilmore, Yee Soong, Richard Koepsel, Zhu Liu
  • Publication number: 20100299782
    Abstract: The invention provides compositions and methods for manipulating the exchange of water and/or carbon dioxide (CO2) through plant stomata by controlling CO2 sensor genes. The invention provides compositions and methods for enhancing or optimizing biomass accumulation in a plant. The invention provides compositions and methods for for opening or closing a stomatal pore on a guard cell in the epidermis of a plant. The invention provides compositions and methods for increasing or decreasing oxygenation efficiency and/or carbon fixation in a guard cell in the epidermis of a plant by manipulating expression of a ribulose-1,5-bisphosphate carboxylase/oxygenase. The invention provides promoters for regulating expression of a nucleic acid in a plant guard cell.
    Type: Application
    Filed: April 25, 2008
    Publication date: November 25, 2010
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Julian Schroeder, Maria Israelsson-Nordstrom, Josef M. Kuhn, Yingzhen Yang, Honghong Hu, Aurelien Boisson-Dernier
  • Patent number: 7833778
    Abstract: The present invention describes a method for producing butanol by fermentation of carbohydrates using mixed populations of acidogenic-phase cells and solventogenic-phase cells of Clostridium in a solitary vessel. The present system as described does not require intermittent adjustment of pH or venting of headspace gases. The method provides a process for removal of the butanol product which does not irreversibly harm the cells and conditions are described where such cells may resume butanol synthesis in the same solitary vessel. The invention also describes compositions and biologically pure cultures which comprise the Clostridium cells as disclosed. Also, a biologically pure Clostridium beijerinkii strain NRRL No. B-50244 is disclosed.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: November 16, 2010
    Inventor: Eugene T. Butler, III
  • Publication number: 20100136647
    Abstract: The present invention relates to the field of adherent cell culture. More closely, the invention relates to a method for production of a cell attachment and culture surface, such as a microcarrier, comprising a guanidino-containing ligand, wherein the ligand is coupled via reaction involving a primary amine to the surface which is activated by activation groups such that the final molar ratio of grafted ligand and ungrafted activation groups is above 1.5. Preferably, the ligand density is above 0.5 mmol/g cell culture surface and the remaining activation groups after coupling is less than 0.6 mmol/g cell culture surface. The cell culture surface may be used for various purposes, primarily cell cultivation and virus production.
    Type: Application
    Filed: November 23, 2009
    Publication date: June 3, 2010
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: Mattias Algotsson, Hans Berg, Asa Bjurling, Christian Kaisermayer, Bjorn Noren, Nicholas Thevenin, James Van Alstine
  • Patent number: 7723086
    Abstract: An apparatus for encapsulating cells is disclosed. According to one embodiment, the apparatus includes an indirect-pumping dispenser for dispensing a cell suspension into an encapsulation solution through an outlet of the dispenser. The apparatus also includes a dipping mechanism that is attachable to the outlet of the dispenser. The dipping mechanism is adapted to dip the dispenser outlet in the encapsulation solution to allow the cell suspension dispensed thereat to come into contact with the encapsulation solution.
    Type: Grant
    Filed: June 16, 2004
    Date of Patent: May 25, 2010
    Assignee: Agency for Science, Technology + Research
    Inventors: Hanry Yu, Hai Ting Ho, Jing Zhang
  • Patent number: 7700355
    Abstract: A porous matrix, preparation thereof, and methods of using the same. The porous matrix of calcium alginate is prepared using a plurality of particles containing a multivalent cation, admixing the particles with ionic cross-linked polysaccharides and water to form a mixture, introducing a cross linker to solidify the mixture, dissolving the particles of the mixture in an acid to form a porous structure, and neutralizing and cross-linking the porous structure.
    Type: Grant
    Filed: January 7, 2005
    Date of Patent: April 20, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Chun-Jen Liao, Jui-Hsiang Chen, Chen-Chi Tsai, Yung-Chih Wu, Shu-Fang Chiang, Yi-Jung Hsiang
  • Publication number: 20100093053
    Abstract: We disclose a particle comprising a matrix coated thereon and having a positive charge, the particle being of a size to allow aggregation of primate or human stem cells attached thereto. The particle may comprise a substantially elongate, cylindrical or rod shaped particle having a longest dimension of between 50 ?m and 400 ?m, such as about 200 ?m. It may have a cross sectional dimension of between 20 ?m and 30 ?m. The particle may comprise a substantially compact or spherical shaped particle having a size of between about 20 ?m and about 120 ?m, for example about 65 ?m. We also disclose a method of propagating primate or human stem cells, the method comprising: providing first and second primate or human stem cells attached to first and second respective particles, allowing the first primate or human stem cell to contact the second primate or human stem cell to form an aggregate of cells and culturing the aggregate to propagate the primate or human stem cells for at least one passage.
    Type: Application
    Filed: July 3, 2009
    Publication date: April 15, 2010
    Applicant: Agency for Science, Technology and Research
    Inventors: Steve Oh, Marti Lecina, Andre Choo, Shaul Reuveny, Robert Zweigert, Allen Chen
  • Patent number: 7695973
    Abstract: The present invention provides methods for quantitation of glycated protein in a biological sample using a solid support matrix by making a first bound protein measurement total bound protein under conditions where both glycated and non-glycated protein bind to the support in making a second bound protein measurement under conditions where glycated protein is bound to the support and non-glycated protein is not substantially bound. Diagnostic devices and kits comprising the methods of the present invention are also provided.
    Type: Grant
    Filed: February 7, 2007
    Date of Patent: April 13, 2010
    Assignee: Scripps Laboratories, Inc.
    Inventors: Ralph P. McCroskey, Cameron E. Melton
  • Publication number: 20100015097
    Abstract: The present invention relates to a method of making a sorbent, comprising the steeps of crushing seed husks, acid hydrolysis with extraction of water-soluble ballast substances and formation of the target composition of lignin, cellulose and melanin, water rinsing and drying, wherein the acid hydrolysis is made with an 0.1-36% acid solution during 0.3-4.5 hours in the boiling mode under pressure in the range 0.1-0.7 MPa, rinsing is made with water and/or a 0.1-1.0% alkali solution and then softened water, and the product is subsequently dried. The sorbent comprises a porous multilevel matrix on the basis of lignin, cellulose and melanin. The invention further discloses the sorbent and its uses as for prophylaxis and treatment of toxicoses, free-radical pathologies, diarrhea syndromes which are caused by ecotoxicants, viral and bacterial infections, for prophylactic and treatment of animal diseases caused by mycotoxins, pesticides, bad-quality forages in all kinds of animals.
    Type: Application
    Filed: July 10, 2007
    Publication date: January 21, 2010
    Inventors: Viktoria Alexeevna Lapina, Alexander Evgenievich Dontsov, Igor Viktorovich Nasonov
  • Patent number: 7611701
    Abstract: A process for the preparation of an enzyme-containing granulate is disclosed where an aqueous enzyme-containing liquid is mixed with an edible carbohydrate-based solid carrier, such as starch, mechanically processed into granules, and subsequently dried. This enzyme granulate is suitable for the manufacture of animal feed compositions by mixing feed ingredients with the granulate, treating with steam and pelleting. The compositions optimally show improved enzyme stability during the pelleting process.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: November 3, 2009
    Assignee: BASF Aktiengesellschaft
    Inventors: Rudolph Carolus Maria Barendse, Gabriel Marinus Henricus Meesters, Hans-Peter Harz