Bacteria Or Actinomycetales; Media Therefor Patents (Class 435/252.1)
  • Publication number: 20140329840
    Abstract: 7-(substituted) derivatives of 7H-pyrrolo[3,2-f]-quinazoline-1,3-diamines, derivative thereof, and methods of using them are provided. The pharmaceutical formulations prepared from the compounds can be used to treat a variety of conditions, which include, but are not limited to bacterial and fungal infections. The compounds can also be used as a sterilizing or disinfecting agent.
    Type: Application
    Filed: May 5, 2014
    Publication date: November 6, 2014
    Applicant: Georgia Tech Research Corporation
    Inventors: Bharath Srinivasan, Jeffrey Skolnick, Hongyi Zhou
  • Publication number: 20140329295
    Abstract: A process including: (a) mixing a microbial biomass, comprising oil-containing microbes, and at least one grinding agent capable of absorbing oil, to provide a disrupted biomass mix; (b) blending at least one binding agent with said disrupted biomass mix to provide a fixable mix capable of forming a solid pellet; and, (c) forming the solid pellet from the fixable mix. The process optionally includes extracting the solid pellet with a solvent to provide an extracted microbial oil.
    Type: Application
    Filed: July 18, 2014
    Publication date: November 6, 2014
    Inventors: MARIOS AVGOUSTI, TIMOTHY ALLAN BELL, OLIVER WALTER GUTSCHE, KEITH W. HUTCHENSON, ROBERT D. ORLANDI
  • Publication number: 20140329296
    Abstract: The present disclosure pertains to novel isolated cellulolytic extreme thermophilic bacterial cells belonging to the genus Caldicellulosiruptor, mutants thereof, isolated strains, microbial cultures and microbial compositions. The novel bacteria are in particular suitable for the production of fermentation products such as ethanol and lactic acid from lignocellulosic biomass.
    Type: Application
    Filed: September 21, 2012
    Publication date: November 6, 2014
    Applicant: DIREVO INDUSTRIAL BIOTECHNOLOGY GMBH
    Inventors: Simon Curvers, Vitaly Svetlichnyi
  • Publication number: 20140329297
    Abstract: Polymeric thin-film tube connectors, bioreactors, systems and methods are described, the connectors allowing connection of a polymeric thin-film tube of a bioreactor chamber with a complementary part, typically, rigid port of flange of the bioreactor or bioreactor system. Further, bioreactors having a thin-film reactor chamber and one or more connectors are described. The thin-film reactor chamber can have a thin-film wall for enclosing culture medium and microorganisms. The connector can include a flexible boot. An opening of the thin-film wall couples to the flexible boot. The thin-film wall can extend through a reactor end of the flexible boot and can rest against an interior surface of the flexible boot. The connectors are particularly advantageous for connecting standard utilities in a bioreactor system to thin-film bioreactor chambers or capsules having a thin-film tubular opening.
    Type: Application
    Filed: November 29, 2012
    Publication date: November 6, 2014
    Inventor: John E. Longan
  • Patent number: 8877178
    Abstract: According to the present invention there are provided methods of use in companion animals of probiotic bacteria of the genus Bifidobacteria.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: November 4, 2014
    Assignees: The Iams Company, Alimentary Health Ltd.
    Inventors: Thomas William-Maxwell Boileau, Michael Anthony Ceddia, Gary Mitchell Davenport, Barry Pius Kiely, Liam Diarmuid O'Mahony, Gregory Dean Sunvold, Mark Alan Tetrick, Robert Jason Vickers
  • Publication number: 20140322172
    Abstract: This invention provides the use of a microorganism capable of improving both lipid metabolism and sugar metabolism. Specifically, the invention relates to: a lipid metabolism and/or sugar metabolism improver comprising, as an active ingredient, a bacterial cell selected from bacteria belonging to the genus Lactobacillus and the genus Bifidobacterium, a treated product of the bacterial cell, or a mixture thereof, having dual-agonistic activities to peroxisome proliferator activated receptor (PPAR)? and peroxisome proliferator activated receptor (PPAR)?; to a food or a beverage comprising the improver; and to a pharmaceutical composition comprising the improver.
    Type: Application
    Filed: December 6, 2012
    Publication date: October 30, 2014
    Applicant: CALPIS CO., LTD.
    Inventors: Futoshi Nakamura, Nobuhisa Ashida, Yu Ishida, Shigeru Fujiwara
  • Publication number: 20140322798
    Abstract: This method of restricting methane production in methanogenic bacteria, by the use of the enzyme and coenzyme inhibitors, works during anaerobic reductive dechlorination. Various compounds such as, but not limited to, red yeast rice, vitamin B10 derivatives, and ethanesulfonates are utilized to disrupt these different enzyme and coenzyme systems responsible for the production of methane. This method affects the competition of the methanogen and halo bacteria for the organic hydrogen donors that are injected in the soil and groundwater system during the remediation process.
    Type: Application
    Filed: May 2, 2014
    Publication date: October 30, 2014
    Applicant: Innovative Environmental Technologies, Inc.
    Inventors: Michael Scalzi, Antonis Karachalios
  • Patent number: 8871266
    Abstract: Probiotic microorganisms are micro encapsulated by dispersing the probiotic microorganism in an aqueous suspension of a film forming protein and a carbohydrate; in an oil in water emulsion of a film forming protein and a carbohydrate and a fat; or in an oil which is subsequently dispersed in a film forming protein and a carbohydrate. The emulsion or suspension may be dried to form a powder. The probiotic may be dispersed in oil and then emulsified with the aqueous suspension and then dried to produce an encapsulated oil be dried to produce a powder. Oil suspended probiotics may be preferred where the probiotic is water sensitive. The preferred protein is casein or whey protein and the carbohydrate may be a resistant starch or a saccharide with a reducing sugar group. Where the probiotic is oxygen sensitive the protein carbohydrate is heated to create Maillard reaction products in the encapsulating film.
    Type: Grant
    Filed: March 30, 2004
    Date of Patent: October 28, 2014
    Assignee: Commonwealth Scientific & Industrial Research Organisation
    Inventors: Ross Crittenden, Luz Sanguansri, Mary Ann Augustin
  • Patent number: 8865156
    Abstract: The invention provides compositions comprising one or more isolated LDH-deficient mutans streptococcus strains and one or more isolated S. oralis strains and/or one or more isolated S. uberis strains. Compositions of the invention are useful to maintain oral health, by for example treating and/or preventing one or more symptoms of dental caries, periodontitis and/or other oral cavity diseases or wounds.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: October 21, 2014
    Assignee: Oragenics, Inc.
    Inventor: Jeffrey D. Hillman
  • Publication number: 20140308733
    Abstract: The present application relates to a method for inducing germination of a spore forming bacterium, specifically, a method for inducing germination of a spore forming bacterium, comprising: using one or more compounds having a phenolic backbone to induce germination of a spore forming bacterium selected from the group consisting of the genus Bacillus, the genus Geobacillus, and the genus Aeribacillus; to a germination inducer for a spore forming bacterium; and to a kit for use in germination of a spore forming bacterium.
    Type: Application
    Filed: September 6, 2012
    Publication date: October 16, 2014
    Inventors: Toki Nishiyama, Nobuhisa Ashida, Gentaro Yasuda, Yukie Tadano
  • Publication number: 20140308367
    Abstract: Provided herein are methods and compositions for treatment of a microbial infection or a microbial biofilm in a subject or on a surface by administering to the subject or surface determined to have or suspected of having a microbial infection/film an antimicrobial agent in combination with a silver-containing compound (e.g., a silver salt). In some embodiments, a silver-containing compound can increase activity of the antimicrobial agent. In other embodiments, addition of a silver-containing compound to an antimicrobial agent can expand the antimicrobial spectrum of the antimicrobial agent such that the antimicrobial agent originally indicated for treatment of one microbial strain (e.g., Gram-positive microbes) becomes effective for treating additional microbial strains (e.g., Gram-negative microbes). Other aspects relating to methods and compositions for delivering an agent to a microbe by increasing the membrane permeability of the microbe are also provided herein.
    Type: Application
    Filed: October 26, 2012
    Publication date: October 16, 2014
    Inventors: James J. Collins, J. Ruben Morones-Ramirez, Jonathan Alexander Winkler, Catherine S. Spina
  • Patent number: 8859281
    Abstract: The present invention is directed generally to eukaryotic cells comprising single-celled organisms that are introduced into the eukaryotic cell through human intervention and which transfer to daughter cells of the eukaryotic cell through at least five cell divisions, and methods of introducing such single-celled organisms into eukaryotic cells. The invention also provides methods of using such eukaryotic cells. The invention further provides single-celled organisms that introduce a phenotype to eukaryotic cells that is maintained in daughter cells. The invention additionally provides eukaryotic cells containing magnetotactic bacteria.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: October 14, 2014
    Assignee: Bell Biosystems, Inc.
    Inventors: Caleb B. Bell, III, Alexey Bazarov
  • Patent number: 8859258
    Abstract: A composite oil displacement agent contains the following main components: 20 to 40% of microorganism, 6 to 30% of surfactant, 5 to 10% of macromolecular modifier, 1 to 5% of viscosity reducer, 1 to 5% of additive and the balance of water. The preparation method thereof comprises the steps of: in proportion by weight, adding the microorganism, the surfactant, the macromolecular modifier, the viscosity reducer, the additive, and the water to a reactor provided with a stirring device, and stirring the components for 1.5 to 2 h at room temperature to obtain the finished product.
    Type: Grant
    Filed: June 2, 2011
    Date of Patent: October 14, 2014
    Inventor: Yinhai Yang
  • Publication number: 20140302564
    Abstract: A method for sterilizing microbial cells is provided. According to the method, microbial cells or a culture containing microbial cells are treated with a polyethylene glycol-based nonionic surfactant so that almost all of the microbial cells are sterilized while the enzyme activity expressed in the microbial cells is maintained at a high level. A method for sterilizing microbial cells and a material containing the sterilized microbial cells, in which the microbial cells are sterilized using a polyethylene glycol-based nonionic surfactant, can be used for foods so that the microbial cells are sterilized to be used in food production. Further, a material containing sterilized microbial cells can be used in processes for preparing tagatose, in which Corynebacterium genus microbial cells that produce Galactose and/or Arabinose isomerase are sterilized using a polyethylene glycol-based nonionic surfactant.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Inventors: Jin Ha Kim, Yong Mi Lee, Seong Bo Kim, Taek Beom Kim, Yang Hee Kim, Seung Won Park
  • Publication number: 20140301994
    Abstract: The invention relates to an anhydrous mixture of biologically active probiotic bacteria for topical administration and methods of making thereof. The mixture of the invention is used for hydrating the skin, reducing and preventing fine lines and wrinkles, treating acne and decreasing skin inflammation.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 9, 2014
    Inventors: Andrew M. Klapper, Spencer J. Malkin
  • Publication number: 20140301995
    Abstract: The invention is based on a correlation observed between serotonin level and intestinal flora. The invention relates to a relative proportion of bifidobacteria in the intestine and in particular to a product increasing the ratio of bifidobacteria to Clostridia, to be used for raising the serotonin level. The invention also relates to a method for estimating a health risk associated with serotonin depletion by determining a relative proportion between bifidobacteria or Clostridia in the intestine or their ratio to one another. The invention further relates to a method for selecting a form of therapy for raising the serotonin level by determining a relative proportion between bifidobacteria or Clostridia in the intestine or their ratio to one another.
    Type: Application
    Filed: October 12, 2012
    Publication date: October 9, 2014
    Inventors: Annika Mayra-Makinen, Eveliina Munukka
  • Publication number: 20140302093
    Abstract: The present invention pertains to microorganisms of the species Bacteroides xylanisolvens expressing a core-1 antigen on their surface. These microorganisms are in particular useful for the prophylaxis and treatment of core-1 positive diseases and are particularly characterized by a stable, homogenous high core-1 expression. Also provided are pharmaceutical compositions which comprise respective core-1 positive microorganisms or fractions thereof.
    Type: Application
    Filed: August 22, 2012
    Publication date: October 9, 2014
    Applicant: GLYCOTOPE GMBH
    Inventors: Steffen Goletz, Philippe Ulsemer, Kawe Toutounian
  • Patent number: 8852886
    Abstract: The invention provides for genetically modified Bacillus host cells having decreased cytoplasmic reductase activity, such as decreased TrxA activity, and a nucleic acid encoding a heterologous Staphylococcal oxidase. The invention also provides for methods of producing di-sulfide bond containing proteins using the host cells of the invention and methods of improving protein folding using the host cell of the invention.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: October 7, 2014
    Assignee: Danisco US Inc.
    Inventors: Jean-Yves Francois Dubois, Roelof Hendrik Matthijs Kouwen, Jan Maarten Van Dijl
  • Patent number: 8852917
    Abstract: The present invention relates to a new bacteriocin, to microbial strains which can produce it and to uses of the bacteriocin and the strains. The bacteriocin is effective against Clostridium difficile and Listeria monocytogenes amongst other organisms.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: October 7, 2014
    Assignees: University College Cork, TEAGASC, The Agriculture and Food Development Authority
    Inventors: Colin Hill, Mary Rea, Paul Ross
  • Publication number: 20140294801
    Abstract: The present invention provides an improved and specific mRNA interferase and related methods of protein-based mRNA interference.
    Type: Application
    Filed: August 3, 2012
    Publication date: October 2, 2014
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Masayori Inouye, Yoshihiro Yamaguchi
  • Publication number: 20140294907
    Abstract: Disclosed herein are methods for preventing biofilm formation on a surface. The present disclosure also relates to anti-biofilm forming agents, to methods of producing and using them, and to anti-fouling coatings produced therefrom.
    Type: Application
    Filed: June 16, 2014
    Publication date: October 2, 2014
    Inventor: Cynthia K. Bruno
  • Publication number: 20140294774
    Abstract: Described is the use of Eubacterium hallii et rel. and/or Alcaligenes faecalis et rel., as well as pharmaceutical, food, or feed compositions comprising these bacteria as a medicament, in particular, for preventing and/or treating insulin resistance and/or insulin resistance-related complications such as metabolic syndrome, dyslipidemia and type 2 diabetes mellitus, as well as insulin resistance in endocrine diseases (e.g., obese subjects with type 1 diabetes mellitus, Cushing's disease and lipodystrophy syndromes. Also described is a method for preventing and/or treating insulin resistance and/or insulin resistance-related complications such as dyslipidemia and type 2 diabetes mellitus as well as insulin resistance in endocrine diseases (e.g., obese subjects with type 1 diabetes mellitus, Cushing's disease and lipodystrophy syndromes) in a subject in need thereof, the method comprising the step of increasing the level of Eubacterium hallii et rel. and/or Alcaligenes faecalis et rel. in the small intestine.
    Type: Application
    Filed: August 30, 2012
    Publication date: October 2, 2014
    Applicants: WAGENINGEN UNIVERSITEIT, ACADEMISCH MEDISCH CENTRUM
    Inventors: Max Nieuwdorp, Willem Meindert De Vos
  • Patent number: 8846334
    Abstract: The disclosure provides culture devices and methods useful for detecting acid-producing bacteria in a sample. The devices include a nutrient medium and a pH indicator to detect and differentiate acid-producing microorganisms, such as lactic acid bacteria. Methods of use include detecting or enumerating acid-producing microorganisms. The methods further provide for the detection of gas-producing acid-producing bacteria.
    Type: Grant
    Filed: June 15, 2010
    Date of Patent: September 30, 2014
    Assignee: 3M Innovative Properties Company
    Inventors: Robert F. Young, Patrick A. Mach, Michael E. Hughes, Christine A. Binsfeld, Jason W. Bjork, Mara S. Reif-Wenner, Henry J. Lubrant
  • Patent number: 8846082
    Abstract: An encapsulation system is provided comprising nitrogen-purge, instant bonding encapsulation method. Specifically, the encapsulation system comprises a composition, a two-piece capsule comprising a capsule cap and a capsule body; a gas to purge oxygen from the composition within the capsule; and a sealing solution to seal the capsule cap to the capsule body. Associated methods for encapsulating compositions using the encapsulation system are also provided.
    Type: Grant
    Filed: March 21, 2006
    Date of Patent: September 30, 2014
    Assignee: Vita-Herb Nutriceuticals, Inc.
    Inventor: Bing Baksh
  • Patent number: 8846372
    Abstract: The use of free, extractable lipids found in bacteria for identification of bacterial species and subspecies is described. Bacteria have been found to differ sufficiently in their extracted lipid compositions to effect identification using thin layer chromatographic techniques. Burkholderia pseudomallei, Burkholderia thailandensis, and Burkholderia mallei have been distinguished in this manner. Lipopeptides specific to Mycobacterium avium subspecies paratuberculosis, but not to the closely related bacterium Mycobacterium avium subspecies avium have also been used as a basis for bacterial subspecies identification using mass spectrometry and seroreactivity.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: September 30, 2014
    Assignee: Colorado State University Research Foundation
    Inventors: Torsten Manfred Eckstein, Julia Mitsue Inamine Eckstein
  • Publication number: 20140286920
    Abstract: The invention is based on a correlation observed between visceral fat and gut flora. The invention relates to a product increasing the relative proportion of bifidobacteria in the intestines and to be used for preventing formation of visceral fat or for reducing the amount thereof in the body. In particular, the product increases the ratio of bifidobacteria to Clostridia. The invention also relates to determining visceral fat in the body by determining the relative proportion of bifidobacteria or Clostridia or their ratio to each other in the intestines. The invention further relates to a method for estimating, in the same manner, the health risk associated with obesity.
    Type: Application
    Filed: October 12, 2012
    Publication date: September 25, 2014
    Applicant: Gut Guide Oy
    Inventors: Annika Mayra-Makinen, Eveliina Munukka
  • Publication number: 20140287482
    Abstract: The present application discloses a novel biological material transfer apparatus and methods of using the same. The apparatus is made up of double walled barrel shaped tip chamber to house either the single tip or multiple tips of fixed size and a unique ball head to transfer the biological material from one location to another location in an aseptic method. The tip has a fixed shape and size and a ball head which makes the process of picking and transferring of biological material easy, safe and convenient to use with large scale samples. The apparatus is further equipped with an ultra violet light which sterilize the tips just before their use making the entire process of transferring of biological material highly aseptic.
    Type: Application
    Filed: March 23, 2013
    Publication date: September 25, 2014
    Applicant: King Abdulaziz City for Science and Technology (KACST)
    Inventor: MOHAMMAD AHMED KHIYAMI
  • Publication number: 20140287473
    Abstract: The present invention relates methods and compositions for producing an organic substance from fermenting microorganism using simultaneous saccharification and fermentation. One aspect of the invention provides producing alcohol by simultaneous saccharification and fermentation by combining a cellulosic substrate, and whole fermentation broth, and an ethanologenic microorganism under conditions conducive both to hydrolysis of cellulose to glucose and to conversion of glucose to alcohol.
    Type: Application
    Filed: March 22, 2013
    Publication date: September 25, 2014
    Applicant: DANISCO US INC.
    Inventors: Mian Li, Colin Mitchinson, Landon M. Steele
  • Publication number: 20140287483
    Abstract: New semiconductor nanoparticles and manufacturing technologies, including novel methods, systems, and compositions, are provided herein. Robust, reproducible production of large amounts of semiconductor nanoparticles, such as quantum dots, from bacterial cultures during continuous growth is provided, without a need for extensive post growth processing or modification. The result is a novel semiconductor of nanoparticle dimensions and quality that is suitable for commercial applications in lighting, display, imaging, diagnostics, photovoltaics and hydrogen generation, for example. In one embodiment, bacterial-based synthesis methods for producing nanocrystal semiconductor quantum dots are provided by aqueous, environmentally friendly media and methods.
    Type: Application
    Filed: August 16, 2012
    Publication date: September 25, 2014
    Applicant: LEHIGH UNIVERSITY
    Inventors: Bryan Berger, Steven McIntosh
  • Patent number: 8840880
    Abstract: According to the invention there is provided a strain of lactic acid bacteria of the species Bifidobacteria globosum obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacteria globosum of the present invention are also provided.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: September 23, 2014
    Assignees: The Iams Company, Alimentary Health, Ltd.
    Inventors: Thomas William-Maxwell Boileau, Michael Anthony Ceddia, John Kevin Collins, Gary Mitchell Davenport, Barry Pius Kiely, Liam Diarmuid O'Mahony, Gregory Dean Sunvold, Mark Alan Tetrick, Robert Jason Vickers
  • Patent number: 8841112
    Abstract: The present invention relates to methods for culturing spirochetes, in particular Borrelia burgdorferi. The present invention also provides methods of identifying spirochetes present in a biological sample. The present invention further provides methods of diagnosing diseases cause by a spirochete infection, such as Lyme disease, syphilis, and multiple sclerosis. The present invention further provides methods for identifying spirochete susceptibilities to antimicrobials and antimicrobial compositions and cocktails. The present invention also provides methods for treating subjects suspected of having a spirochete infection.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: September 23, 2014
    Assignee: Advanced Laboratory Services, Inc.
    Inventors: Eva T. Sapi, Timothy Robert Schwartz, Namrata Pabbati
  • Publication number: 20140273117
    Abstract: The present invention comprises a process to produce organic products from a single-carbon substrate; microbial compositions used in the process; and a process to isolate microorganisms for the process.
    Type: Application
    Filed: March 16, 2014
    Publication date: September 18, 2014
    Inventor: Richard Allen Kohn
  • Publication number: 20140273108
    Abstract: A method of producing hydrolysate from cellulosic material by adding hydrothermally treated stillage or a fraction thereof to cellulosic material, treating the mixture of hydrothermally treated stillage and cellulosic material with at least one hydrolyzing enzyme, and hydrolyzing and converting complex carbohydrates in the cellulosic material. The hydrolysate produced by the method. Ethanol, organic acids, and organism metabolites produced by the method. Biomass produced by the method. A method of increasing sugar production rate and yield of sugars from cellulosic material by adding hydrothermally treated stillage or a fraction thereof to cellulosic material, treating the mixture of hydrothermally treated stillage and cellulosic material with at least one hydrolyzing enzyme, and hydrolyzing complex carbohydrates in the cellulosic material and forming sugars.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: Valicor, Inc
    Inventor: James Robert Bleyer
  • Publication number: 20140260462
    Abstract: Methods of increasing the amount of iron (Fe) and potassium (K) available in soil to plants residing in the soil. A composition comprising at least one microorganism capable of oxidizing Fe(II) bound in at least one phyllosilicate and releasing Fe and K from the at least one phyllosilicate to increase availability of Fe and K to plants in soil treated with the composition relative to plants in untreated soil. Compositions and microorganisms capable of oxidizing Fe(II) and K are disclosed.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION
    Inventors: Evgenya Shelobolina, Eric Roden, Jason Benzine, Mai Yia Xiong
  • Patent number: 8835140
    Abstract: A process for the use of peracid compositions to eliminate and/or control the growth of undesirable bacteria, including contaminating bacteria, in the fermentation production of alcohol is disclosed. Beneficially, the peracid compositions and methods of use of the same do not interfere or inhibit the growth or replication of yeast and have low or no adverse environmental impact.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: September 16, 2014
    Assignee: Ecolab USA Inc.
    Inventors: Peter J. Fernholz, Jay Kummet
  • Patent number: 8835152
    Abstract: Compositions of peptides and surface-active agents are described, as are methods of making and using such compositions. The compositions are capable of affecting metabolic rates in biological systems, and to accelerate nutrient uptake without a concomitant increase in biofilm production.
    Type: Grant
    Filed: December 4, 2012
    Date of Patent: September 16, 2014
    Assignee: Advanced Biocatalytics Corporation
    Inventor: Carl W. Podella
  • Publication number: 20140256021
    Abstract: A biofilter media has one or more of a set of desired physical characteristics. The set of physical characteristics includes a sphericity of 0.75 to 1, a particle size of 1 to 16 or 4 to 8 mm, a uniformity coefficient of 2 or less and a surface area of 800 to 2000 m2/m3of media. The media is coated, supports microorganisms and is used to treat a waste gas stream.
    Type: Application
    Filed: May 21, 2014
    Publication date: September 11, 2014
    Applicant: BIOREM TECHNOLOGIES INC
    Inventors: Hidayat HUSAIN, Brian P. HERNER
  • Publication number: 20140255352
    Abstract: Compositions and methods for treating and/or preventing bacterial infections in animals such as bovines are provided. The compositions and methods utilize the predatory bacterium Bdellovibrio bacteriovorus to treat and/or prevent infections such as infectious bovine keratoconjunctivitis (IBK) and bovine respiratory disease (BRD). Use of the bacterium obviates the need for chemotherapeutic measures.
    Type: Application
    Filed: October 1, 2012
    Publication date: September 11, 2014
    Inventors: Melanie J. Boileau, Kenneth D. Clinkenbeard, Rinosh Joshua Mani, John J. Iandolo, Huda Mussa
  • Publication number: 20140256923
    Abstract: A compound represented by the following Structural Formula (A) or a salt thereof. The compound or the salt thereof is suitably produced from a microorganism belonging to the genus Saccharothrix and can be suitably used as a prostaglandin production inhibitor.
    Type: Application
    Filed: April 29, 2014
    Publication date: September 11, 2014
    Applicant: Microbial Chemistry Research Foundation
    Inventors: Koichi NAKAE, Fukiko KOJIMA
  • Patent number: 8828238
    Abstract: A novel thermophilic bacterium is provided, which has a 16S rDNA sequence as set forth in SEQ ID NO. 1. The thermophilic bacterium excretes extracellular proteins having excellent metal-ion binding ability, being useful in the treatment of boiler equipment, pipelines, geothermal wells or industrial wastewater or hard water.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: September 9, 2014
    Assignee: Industrial Technology Research Instiute
    Inventors: Yin-Lung Han, Tai-Rong Guo, Jo-Shu Chang, I-Ju Chou
  • Patent number: 8828681
    Abstract: The present invention is directed generally to eukaryotic cells comprising single-celled organisms that are introduced into the eukaryotic cell through human intervention and which transfer to daughter cells of the eukaryotic cell through at least five cell divisions, and methods of introducing such single-celled organisms into eukaryotic cells. The invention also provides methods of using such eukaryotic cells. The invention further provides single-celled organisms that introduce a phenotype to eukaryotic cells that is maintained in daughter cells. The invention additionally provides eukaryotic cells containing magnetotactic bacteria.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 9, 2014
    Assignee: Bell Biosystems, Inc.
    Inventors: Caleb B. Bell, III, Alexey Bazarov
  • Publication number: 20140248396
    Abstract: The invention relates to a probiotic microorganism at least partially coated with a poly glutamic acid, for example poly-?-glutamic acid (?-PGA). The invention also relates to an ingestible product comprising the probiotic microorganism at least partially coated with a poly glutamic acid and a method of making a probiotic microorganism at least partially coated with a poly glutamic acid. The invention also relates to a method of making poly-?-glutamic acid (?-PGA).
    Type: Application
    Filed: August 31, 2012
    Publication date: September 4, 2014
    Applicant: University of Wolverhampton
    Inventors: Iza Radecka, David Hill, Terence Bartlett, Aditya Bhat, Gopal Kedia
  • Patent number: 8822193
    Abstract: A species of Burkholderia sp with no known pathogenicity to vertebrates but with pesticidal activity (e.g., plants, insects, fungi, weeds and nematodes) is provided. Also provided are natural products derived from a culture of said species and methods of controlling pests using said natural products.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 2, 2014
    Assignee: Marrone Bio Innovations, Inc.
    Inventors: Ratnakar Asolkar, Marja Koivunen, Pamela Marrone, Ana Lucia Cordova-Krevlos, Huazhang Huang
  • Publication number: 20140242635
    Abstract: The present invention relates to a fermentation process comprising a fermentation step of growing a strain of Corynebacterium diphtheriae in medium in a fermenter under conditions of agitation sufficient to maintain a homogenous culture and limited aeration such that pO2 within the culture falls to less than 4% for the majority of the fermentation step.
    Type: Application
    Filed: March 14, 2014
    Publication date: August 28, 2014
    Applicant: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: Philippe Marc Helene DEHOTTAY, Sandrine DESSOY, Olivier Marc Serge Ghislain LALOUX, Marc Roger Fernand ORVAL
  • Patent number: 8815548
    Abstract: The invention features methods for producing isoprene from cultured cells using a feedback-resistant mevalonate kinase polypeptide, such as an archaeal mevalonate kinase polypeptide. The resulting isoprene compositions may have increased yields and/or purity of isoprene.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: August 26, 2014
    Assignees: Danisco US Inc., The Goodyear Tire & Rubber Company
    Inventors: Zachary Q. Beck, Anthony R. Calabria, Michael C. Miller, Alex T. Nielsen, Dmitrii V. Vaviline
  • Patent number: 8815545
    Abstract: Disclosed is a novel microorganism which has a malate dehydrogenase activity higher than that of a wild-type. Also, a recombinant vector which has the structure shown in the cleavage map of FIG. 1, a Corynebacteria strain transformed therewith, and a method of producing 5?-xanthosine monophosphate by culturing the transformed strain are disclosed.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: August 26, 2014
    Assignee: CJ CheilJedang Corporation
    Inventors: Jinman Cho, Hye Won Kim, Jinman Lee, Ji-Hye Lee, Yoon Seok Oh, Jang Hee Park
  • Publication number: 20140235500
    Abstract: A system for the high-throughput screening of mechanical properties of cells and/or particles is provided. In certain embodiments the system comprises a first structure comprising a plurality of sample receiving wells; a second structure comprising a plurality of exit ports; a porous structure disposed between said plurality of sample receiving wells and said plurality of exit ports and in communication with said plurality of sample receiving wells and in communication with said plurality of exit ports, and said first structure, said second structure and said porous structure are sealed or configured such that when sufficient pressure is applied to sample receiving wells in said first structure said cells or particles migrate through the porous structure into said exit ports, and wherein the mean or the median pore size of said porous structure is smaller than the mean or median cross-section of a cell or particle that is to be screened.
    Type: Application
    Filed: October 15, 2012
    Publication date: August 21, 2014
    Applicant: The Regents of the University of California
    Inventors: Amy Rowat, Dongping Qi
  • Patent number: 8809048
    Abstract: The object is to provide a technique for modifying a bacterium belonging to the genus Kocuria through genetic engineering for industrially effectively utilizing the bacterium belonging to the genus Kocuria. The above object can be achieved by providing a cyclic plasmid, which has a replication region comprising the base sequence of a DNA-binding protein-like protein gene, the base sequence of a replicase-like protein gene, and the base sequence represented by SEQ ID NO:45, and is autonomously replicable in bacteria. As an example of the aforesaid plasmid, a plasmid containing a base sequence represented by SEQ ID NO:3 or 4 which originates in Kocuria sp. MBE131 strain (FERM P-21885) can be cited.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: August 19, 2014
    Assignee: Independent Administrative Institution, Japan Agency for Marine-Earth Science and Technology
    Inventors: Yukari Ohta, Yuji Hatada, Kozue Mori, Nobuyuki Nakamura
  • Patent number: 8809035
    Abstract: According to the invention there is provided a strain of lactic acid bacteria of the species Bifidobacterium globosum obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacterium globosum of the present invention are also provided.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: August 19, 2014
    Assignees: The Iams Company, Alimentary Health, Ltd.
    Inventors: Thomas William-Maxwell Boileau, Michael Anthony Ceddia, John Kevin Collins, Gary Mitchell Davenport, Barry Pius Kiely, Liam Diarmuid O'Mahony, Gregory Dean Sunvold, Mark Alan Tetrick, Robert Jason Vickers
  • Publication number: 20140227768
    Abstract: The present application discloses a novel microbiological apparatus and methods of using the same. The apparatus is a rolling pen comprising of a socket and a ball with its unique rolling head to transfer a biological material from a first location to a second location in an aseptic manner. Further, the rolling pen apparatus can be used with a pen holder device or with a holder hand device to transfer the biological material a first location to a second location and further to develop a microbiological colony. The invention also discloses the use of rolling pen apparatus attached to a holder hand device in propagating a single biological colony such as bacterial colony or cells.
    Type: Application
    Filed: December 2, 2013
    Publication date: August 14, 2014
    Applicant: King Abdulaziz City for Science and Technology (KACST)
    Inventor: MOHAMMAD AHMED KHIYAMI