Including Structure Located Within Vertically-oriented Bowl And Extending Outwardly From Central Region (e.g., Axis) Thereof Patents (Class 494/67)
  • Patent number: 10940489
    Abstract: A centrifugal separator includes a frame and a drive member configured to rotate a rotating part in relation to the frame around an axis of rotation. The rotating part includes a centrifuge rotor closing a separation chamber. The separation chamber includes a stack of separation discs arranged coaxially around the axis of rotation at a distance from each other such as to form passages between each two adjacent separation discs. The stack of separation discs includes a first type of separation discs having an outer diameter of A or below, and at least one separation disc of a second type having outer diameter B or above, wherein diameter B is larger than diameter A. At least one of the separation discs of the second type is arranged at a position in the disc stack that is within the upper 15% of the total number of separation discs and at least one of the first type of separation disc is arranged axially above the uppermost separation disc of the second type.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: March 9, 2021
    Assignee: ALFA LAVAL CORPORATE AB
    Inventors: Peter Hagqvist, Olle Törnblom, Torbjörn Larsen, Björn Wernerson, Galya Simeonova, Mustafa Rasol
  • Patent number: 10512919
    Abstract: A centrifugal separator for cleaning a gas containing liquid impurities includes a stationary casing, enclosing a separation space and a surrounding side wall, a first end wall and a second end wall. An inlet extends through the stationary casing and permits supply of the gas to be cleaned. A rotating member includes a stack of separation disks rotatable around an axis of rotation by means of a drive member. A gas outlet permits discharge of cleaned gas and comprises an outlet opening through the stationary casing and an upstream portion extending from the outlet opening. A drainage outlet permits discharge of liquid impurities separated from the gas. The drainage outlet is provided in the gas outlet downstream the upstream portion. The gas outlet conveys the liquid impurities to the drainage outlet.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: December 24, 2019
    Assignee: ALFA LAVAL CORPORATE AB
    Inventor: Thomas Eliasson
  • Patent number: 9849467
    Abstract: The invention relates to a disc package for a centrifugal separator and a centrifugal separator provided with a disc package comprising a first set of separation discs and a second set of separation discs. Each separation disc of the first and second sets are provided with a separation surface with is inclined with respect to the radial direction. The separation discs of the first and second sets are arranged coaxially around an axis of rotation at a distance from each other such that to form passages between each two adjacent separation discs. The separation discs of the first set have outer diameters A or below, and the separation discs of the second set have outer diameters B or above, wherein diameter B is larger than diameter A. At least two separation discs of the first set is arranged between every two separation disc of the second set.
    Type: Grant
    Filed: May 13, 2013
    Date of Patent: December 26, 2017
    Assignee: ALFA LAVAL CORPORATE AB
    Inventor: Peter Hagqvist
  • Patent number: 8956271
    Abstract: A method for removing particulates from a fluid, the method including the steps of: producing a laminar flow of the fluid through a single-flow passageway defined by an interior surface of an outer rotor of a centrifuge; and imparting centrifugal force on the fluid in a direction orthogonal to a direction of the flow of the fluid to capture the particulates from the fluid. The method may further comprise rotation of the centrifuge at a speed of 5,000 to 15,000 revolutions per minute. The method may also or alternatively comprise locating the interior surface between 3 and 5 inches from an axis of rotation of the centrifuge.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: February 17, 2015
    Assignee: Fram Group IP LLC
    Inventors: Vipul P. Patel, Allen K. MacKnight, Steven R. Eccles, Leonard Walitt
  • Patent number: 8936766
    Abstract: A lipoaspirate collection device to aid in the collection and processing of human tissue and fluid obtained during liposuction for use in point-of-care cell therapy. The collection device includes a collection body and a collection cap. The collection cap may have a fluid port, a lipoaspirate port, a vacuum port, and a relief valve. Within the central cavity of the collection device, a cone shaped may be positioned such that the apex of the cone is positioned underneath the lipoaspirate inlet through which the lipoaspirate fluid and tissue are introduced.
    Type: Grant
    Filed: October 4, 2011
    Date of Patent: January 20, 2015
    Assignee: SpineSmith Partners, L.P.
    Inventors: Ted Sand, Kevin Dunworth, Greg Forman
  • Patent number: 8808155
    Abstract: A centrifuge concentrator bowl has feed deposited onto a base of the bowl and includes a plurality of recesses at axially spaced positions along a peripheral wall of the bowl. The peripheral wall is formed of a rigid metal skeleton frame of rings and upstanding support members on which is molded a urethane liner material to form an integral structure with the rings located at ribs between the recesses. A fluidization water injection system includes an outer container on the bowl, which also acts as a clamping assembly and a plurality of liquid entry openings through the peripheral wall at the base of the recesses allowing flexing of the peripheral wall in response to changes in pressure in the fluidizing liquid. The bowl is formed of separate sections defined by a bottom concave base section and the cast skeleton wall all clamped together to allow replacement of the separate parts.
    Type: Grant
    Filed: July 13, 2010
    Date of Patent: August 19, 2014
    Assignee: FLSmidth Inc.
    Inventors: Edwin John William Zonneveld, John Douglas Corsan, Michael McLeavy, Michael John Fullam
  • Patent number: 8753253
    Abstract: The present invention relates to a separator for separating air and possibly present solids from a mixture of dental waste water, comprising an air-water separator, wherein a mixture supply tube opens into a centrifuge drum, an air discharge duct extends from the centrifuge drum to the mixture supply tube and the centrifuge drum includes an upper drain edge over which a water outlet is guided onto the outside of the centrifuge drum. In accordance with the invention, the separator is characterized in that the mixture supply tube opens onto a central turbine wheel arranged above the centrifuge drum bottom and an impeller of a waste water delivery pump, which communicates with the water outlet, is arranged on an outside of the centrifuge drum in the vicinity of the centrifuge drum bottom.
    Type: Grant
    Filed: July 28, 2008
    Date of Patent: June 17, 2014
    Inventors: Bruno Pregenzer, Alfred Konzett
  • Patent number: 8747290
    Abstract: The invention relates to a centrifuge for separating a sample into at least two components, comprising a chamber for receiving a sample to be centrifuged. According to the invention, the centrifuge further comprises a means for controlling the progress of the sample separation is located at the chamber.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: June 10, 2014
    Assignee: Miltenyi Biotec GmbH
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Niklas Elmar Neuschäfer, Martin Biehl, Eiad Kabaha, Jürgen Schulz
  • Patent number: 8727132
    Abstract: The invention relates to a system, comprising: a) a sample processing unit, comprising an input port and an output port coupled to a rotating container having at least one sample chamber, the sample processing unit configured provide a first processing step to a sample or to rotate the container so as to apply a centrifugal force to a sample deposited in the chamber and separate at least a first component and a second component of the deposited sample; and b) a sample separation unit coupled to the output port of the sample processing unit, the cell separation unit comprising separation column holder (42), a pump (64) and a plurality of valves (1-11) configured to at least partially control fluid flow through a fluid circuitry and a separation column (40) positioned in the holder, the separation column configured to separate labeled and unlabeled components of sample flowed through the column.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: May 20, 2014
    Assignee: Miltenyi Biotec GmbH
    Inventors: Stefan Miltenyi, Winfried Schimmelpfennig, Holger Lantow, Elmar Niklas Neuschäfer, Martin Biehl, Eiad Kabaha, Jürgen Schulz
  • Patent number: 8636634
    Abstract: Disclosed are a reaction and separation processor and a process for producing biodiesel. The processor is comprised of a stationary casing and a rotor located internal to the casing, with a gap formed between the rotor and casing. A fluid inlet port is located at the upper end of the casing for delivering fluid, which is used to produce the biodiesel, into the reaction zone of the processor, in which the reaction zone is defined as a gap between an upper portion of the rotor and casing. Surface irregularities for inducing fluid turbulence in the reaction zone are located on an inner surface of the casing, an outer surface of the rotor, or both. A rotor inlet port is located at a lower end of the rotor for directing fluid from the reaction zone into the separation zone, which is located within the rotor.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: January 28, 2014
    Assignee: RASP Technologies, LLC
    Inventors: Mark Allen, Robert Miller
  • Patent number: 8535210
    Abstract: A centrifugal blood separation system comprising a rotor, a light source, an optical sensor, a control system, a separation vessel, and an optical cell on the separation vessel. The optical cell has a first extraction port extending radially outwardly into the optical cell, a red blood cell extraction port downstream from the first extraction port and extending into the optical cell beyond the first extraction port; and a dam between said first extraction port and said red blood cell extraction port, having an upper edge and a lower edge, wherein the first extraction port and the red cell extraction port are radially between the upper edge and the lower edge of the dam. Also, a first extraction port having a bore having a first diameter, a lumen having a second diameter smaller than the first diameter, and a frustro-conical passageway coupling the bore to the lumen.
    Type: Grant
    Filed: December 3, 2010
    Date of Patent: September 17, 2013
    Assignee: Terumo BCT, Inc.
    Inventors: Jeremy P. Kolenbrander, Brian M. Holmes, Thomas J. Felt, James R. Ladtkow
  • Patent number: 8511480
    Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: August 20, 2013
    Assignee: ThermoGenesis Corp.
    Inventors: John R. Chapman, Vijay Kumar, Brian K. Cinquini, Phillip D. Kingsley
  • Patent number: 8511479
    Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.
    Type: Grant
    Filed: January 24, 2012
    Date of Patent: August 20, 2013
    Assignee: ThermoGenesis Corp.
    Inventors: John R. Chapman, Vijay Kumar, Brian K. Cinquini, Phillip D. Kingsley
  • Publication number: 20130157833
    Abstract: A cleaning apparatus for polluted scrubber fluid from an exhaust gas scrubber fluid loop includes means for bleeding off part of the polluted scrubber fluid from the scrubber fluid loop, a disc stack centrifugal separator for separating a pollutant phase and a cleaned scrubber fluid from said part. The separator includes a rotor enclosing a separation space with a stack of separating discs, a separator inlet extends into the separating space, a first separator outlet for cleaned scrubber fluid extending from said separating space, and a second separator outlet for the pollutant phase extending from the separating space. The cleaning apparatus includes means for conducting the part to the separator inlet, and means for discharging the cleaned scrubber fluid from the first separator outlet, and means for collecting the pollutant phase from the second separator outlet.
    Type: Application
    Filed: June 15, 2011
    Publication date: June 20, 2013
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Staffan Königsson, Lena Sundquist
  • Patent number: 8226537
    Abstract: A disposable blood separation set of a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber a baffle within a separation area. The baffle may have a plurality of vanes with openings therein. A protruding inlet may have a frustro-conical inner surface that slants radially outwardly from an inlet to a mouth of the protruding inlet. A circumferential well may surround the protruding inlet.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: July 24, 2012
    Assignee: Terumo BCT, Inc.
    Inventors: John Pittinger, Robert Langley, Mary Langley, legal representative, Logan Fender
  • Patent number: 8177072
    Abstract: A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: May 15, 2012
    Assignee: ThermoGenesis Corp.
    Inventors: John R. Chapman, Vijay Kumar, Brian K. Cinquini, Phillip D. Kingsley
  • Patent number: 8147394
    Abstract: Centrifugation method and chamber for washing and continuous separation of blood constituents. This chamber comprises at least one first intake channel for the blood, at least one second intake channel for a sterile washing solution, at least one first outlet channel for at least one constituent of this blood, and at least one second outlet channel for a fluid composed of said washing solution and of the other blood constituents. The second intake channel has its downstream end continued on its periphery by a circular deflector. The latter extends into the bottom of the chamber and is terminated along its inner cylindrical side wall by a ridge, which defines a passage of annular cross section for the flow of said sterile washing solution.
    Type: Grant
    Filed: February 26, 2007
    Date of Patent: April 3, 2012
    Inventors: Jean-Denis Rochat, Laurent Mosimann
  • Patent number: 8105495
    Abstract: A process for separating platelet rich plasma from a blood sample using a platelet rich plasma separator system is disclosed. The system includes an inner wall having a top edge and a central axis that is surrounded by a depth filter having a capacity to receive all of the erythrocytes in the blood sample, where an inner surface of the inner wall has an angle of about 0.2° from the central axis of the inner wall. The process includes spinning the inner cylinder at its central axis at a speed that separates the erythrocytes from plasma and platelets and causes the erythrocytes to collect against an inner surface of the depth filter. The cylinder is continually spun for a sufficient time to allow substantially all of the erythrocytes to flow up the inner surface and over the top edge into the depth filter, leaving platelet enriched plasma (PRP) in the inner cylinder, such that upon discontinuing the spinning, permits the platelet enriched plasma to flow to the bottom of the inner cylinder.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: January 31, 2012
    Assignees: Hanuman, LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Patent number: 8096422
    Abstract: Disclosed is a separator-concentrator, such as for separating and concentrating platelet-rich-plasma (PRP) from whole blood that is suitable for office use or emergency use for trauma victims. The PRP separator comprises a motorized centrifugal separation assembly and a concentrator assembly. The centrifugal separation assembly comprises a centrifugal drum separator and a motor having a drive axis connected to the centrifugal drum separator. The concentrator assembly comprises a water-removal module for preparing PRP concentrate.
    Type: Grant
    Filed: November 1, 2010
    Date of Patent: January 17, 2012
    Assignees: Hanuman LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Patent number: 8062534
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: November 22, 2011
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Matthew Swift, Nathan Gordon, Barry F. Hecker
  • Patent number: 8021290
    Abstract: A centrifuge is employed to continuously remove particulates from a fluid. In one embodiment, the centrifuge removes small particles of soot from lubricating oil of diesel engines. The fluid is introduced into the centrifuge through a distribution rotor so that vortexes are not propagated in the fluid. Laminar flow of the fluid down the sides of the outer rotor may contribute to the soot-removal effectiveness of the centrifuge.
    Type: Grant
    Filed: November 26, 2007
    Date of Patent: September 20, 2011
    Assignee: Honeywell International Inc.
    Inventors: Vipul P. Patel, Allen K. MacKnight, Steven R. Eccles, Leonard Walitt
  • Patent number: 7998052
    Abstract: A rotor having variable volumes adapted for collecting and centrifuging biological fluids including an impermeable flexible body having a cylindrical shape with stretchable vertical walls and semi pliant base and a rigid circular member seamlessly joined to the top of the flexible body.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: August 16, 2011
    Inventor: Jacques Chammas
  • Publication number: 20110195832
    Abstract: A separating disk for a disk package of a centrifuge rotor has a tapering shape and extends around an axis (x) of rotation, and along a rotary symmetric surface. The separating disk is configured in such a way that it creates an interspace between the separating disk and an adjacent separating disk in the disk package, and comprises first protrusions extending outwardly from the rotary symmetric surface and second protrusions extending inwardly from the rotary symmetric surface. Each first and second protrusion defines a contact zone adapted to abut the adjacent separating disk. The contact zone of the first protrusions is displaced in relation to the contact zone of the second protrusions. The first and second protrusions are provided after each other in the peripheral direction of the separating disk.
    Type: Application
    Filed: September 30, 2009
    Publication date: August 11, 2011
    Applicant: ALFA LAVAL CORPORATE AB
    Inventors: Lars Johan Rudman, Sven Olov Olsson, Kjell Klintenstedt
  • Patent number: 7976796
    Abstract: A centrifuge tube assembly includes an elongate tubular receptacle having a capped upper end. The capped upper end includes a single inlet/outlet port formed therethrough for communication with an interior of the tubular receptacle. A flexible aspiration pipe is communicably engaged with the inlet/outlet port for extending longitudinally through the cylindrical receptacle. A sealing diaphragm is attached to a distal end of the pipe. The diaphragm is longitudinally movable within the tubular receptacle and sealably interengages an interior wall of the receptacle. Biological products are introduced into and aspirated from the receptacle below the diaphragm by the fluid conducting pipe.
    Type: Grant
    Filed: June 29, 2009
    Date of Patent: July 12, 2011
    Assignee: Emcyte Corp.
    Inventors: Emery Smith, Patrick Pennie, David K. Buzenius
  • Patent number: 7963901
    Abstract: A disposable blood separation set of a centrifugal blood processing system comprising a blood processing chamber adapted to be mounted on a rotor of a centrifuge; a frustro-conical cell separation chamber in fluid communication with the processing chamber, the cell separation chamber having a protruding inlet therein. The protruding inlet may have a frustro-conical inner surface that slants radially outwardly from an inlet to a mouth of the protruding inlet. A circumferential well may surround the protruding inlet. The cell separation chamber may have a baffle within a separation area. The baffle may have a plurality of vanes with openings therein.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: June 21, 2011
    Assignee: CaridianBCT, Inc.
    Inventors: Robert W. Langley, John Pittinger, Logan Fender
  • Patent number: 7959546
    Abstract: A centrifuge is employed to continuously remove particulates from a fluid. In one embodiment, the centrifuge removes small particles of soot from lubricating oil of large diesel engines. The fluid in introduced into the centrifuge through an inducer so that vortexes are not propagated in the fluid. Flow constrainers and flow straighteners maintain laminar flow of the fluid as it passes axially through the centrifuge. An exducer decelerates the fluid prior to its exit from the centrifuge. The exducer thus contributes to maintaining laminar flow conditions. Laminar flow may contribute to the soot-removal effectiveness of the centrifuge.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: June 14, 2011
    Assignee: Honeywell International Inc.
    Inventors: Vipul P. Patel, Allen K. MacKnight
  • Patent number: 7954646
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: June 7, 2011
    Assignee: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Jennifer E. Woodell-May, Joel C. Higgins, Brandon Miller
  • Patent number: 7918350
    Abstract: A separation apparatus and method are employed using a separation channel for rotation about an axis. Such channel includes radially spaced apart inner and outer side wall portions and an end wall portion. An inlet conveys fluid into the channel. A barrier is located in the channel intermediate of the inner and outer side wall portions. A first flow path communicates between upstream and downstream sides of the barrier. A collection region may be located downstream of the barrier for communication with the first flow path. An outer side wall section of the channel may be positioned radially outward of an upstream section thereof. The barrier may join the outer side wall portion along a substantial portion of an axial length of the channel. First and second exit flow paths may allow communication with the channel either upstream or downstream of the barrier or both.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: April 5, 2011
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Richard I. Brown, Alp Akonur, Julie Moriarty
  • Patent number: 7914477
    Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core and other components wherein three separate fluid pathways are provided to allow continuous separation of biological fluids; this apparatus is particularly useful for the administration of extracorporeal photopheresis in that it enhances the collection of the desired blood components, the return of the treated blood, and the speed with which the therapy is administered.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: March 29, 2011
    Assignee: Therakos, Inc.
    Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
  • Patent number: 7914689
    Abstract: An apparatus is disclosed that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: March 29, 2011
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Michael D. Leach, Jennifer E. Woodell-May, Brandon Miller
  • Patent number: 7901343
    Abstract: The present invention provides a self-cleaning drying centrifuge for removing fluid from a concentrated particulate-filled fluid and peeling mostly dried particulate (solid) material from the centrifuge. In some embodiments, a high-efficiency centrifuge performs an initial separation and concentration of small particles from a contaminated fluid, and outputs a clarified fluid for reuse, and periodically purges concentrated particulates with high fluid content. The purged concentrate is then fed into the present invention's drying centrifuge, which substantially reduces the remaining fluid content. In some embodiments, the drying centrifuge is periodically stopped and one or more internal blades (peelers) are rotated around the inner wall of the drying centrifuge bowl to peel the accumulated solids, which drop into a collection container.
    Type: Grant
    Filed: July 30, 2007
    Date of Patent: March 8, 2011
    Assignee: Advanced Products Laboratories, Inc.
    Inventors: Denis J. Dudrey, James N. Gehrking, Adelbert Gorham, Ronald L. Jorgenson, Rodger I. Spears, Lloyd E. Weisert
  • Patent number: 7866485
    Abstract: A Platelet Rich Plasma separator assembly is disclosed. The assembly can include a cylindrical outer wall closed at the top by an upper plate and closed at the bottom. A bottom plate having an upper surface sloped down to a central opening. The top edge of the inner wall terminates at a distance from the upper plate to define an annular erythrocyte passageway therebetween. The inner wall has an outer surface and an inner surface that slopes radially inward from its top edge to its bottom at an angle of from 0.2 to 5 degrees with a central axis of the inner wall. A cylindrical depth filter is positioned between the inner surface of the outer wall and the outer surface of the inner wall in communication with the inner wall through the erythrocyte passageway.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: January 11, 2011
    Assignees: Hanuman, LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Patent number: 7862494
    Abstract: The present invention relates to a centrifuge apparatus. The centrifuge apparatus is operable at certain predetermined parameters depending upon a product to be separated and is useable with a plurality of rotor assemblies. For example, a first rotor assembly of said plurality of rotor assemblies includes a first core having a first core configuration which is contained within a rotor housing of the first rotor assembly to define a first volume capacity such that the product passing through the first rotor assembly having the first volume capacity during rotation of the first rotor assembly in the centrifuge apparatus achieves a first particle separation of the product.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: January 4, 2011
    Assignee: Alfa Wassermann
    Inventors: Sandra Patricia Merino, Steven J. Dalessio, Robin Roy Louis Rudy Otten
  • Patent number: 7845499
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at various fractions in the apparatus. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient. Also selected fractions from the sample can be applied to a patient, either alone or as part of a mixture.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: December 7, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Matthew Swift, Nathan Gordon, Barry F. Hecker
  • Patent number: 7837609
    Abstract: The present invention relates to a centrifuge apparatus. The centrifuge apparatus is operable at certain predetermined parameters depending upon a product to be separated and is useable with a plurality of rotor assemblies. For example, a first rotor assembly of said plurality of rotor assemblies includes a first core having a first core configuration which is contained within a rotor housing of the first rotor assembly to define a first volume capacity such that the product passing through the first rotor assembly having the first volume capacity during rotation of the first rotor assembly in the centrifuge apparatus achieves a first particle separation of the product.
    Type: Grant
    Filed: November 25, 2002
    Date of Patent: November 23, 2010
    Assignee: Alfa Wassermann, Inc.
    Inventors: Sandra Patricia Meriño, Steven J. Dalessio, Robin Roy Louis Rudy Otten
  • Patent number: 7832566
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample and mesenchymal stem cells from bone reaming material. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: November 16, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Michael D. Leach, Joel C. Higgins, Matthew Swift, Nathan Gordon
  • Patent number: 7824559
    Abstract: A PRP separator-concentrator comprising a housing, a separation assembly, and a concentration assembly. The concentration assembly has a concentration sump. An axially concentric rigid stationary outlet tube is secured to the housing and extends through the separation assembly to the sump. The separation assembly is attached to and positioned above the concentration assembly to form a combined separator-concentrator assemblage that is rotatable about the outlet tube. The separation assembly includes a separation chamber lined with a depth filter having pores and passageways that are sized to receive and entrap erythrocytes during centrifuging. The concentration chamber has a floor for supporting desiccated beads and a wall with at least one opening closed with a screen. The concentrator can have a distribution of upright screen supports, the upright screen supports having an inner surface and an outer surface, the cylindrical screen being supported on the outer surface of the upright screen supports.
    Type: Grant
    Filed: January 30, 2006
    Date of Patent: November 2, 2010
    Assignees: Hanumann, LLC, Biomet Biologics, LLC
    Inventors: Randel Dorian, Michael D. Leach
  • Patent number: 7790468
    Abstract: A test object receptacle, capable of measuring a test object in a wide range of concentrations with good accuracy and within a short time, contains a plurality of fine protruding portions inside grooves. The test object receptacle can fix antigens, antibodies and test objects faster than without the protruding portions. Furthermore, the protruding portions are so formed that the surface area thereof increases gradually to the downstream with respect to the movement direction of the test object in the grooves, the detection intensity (intensity of color development) of the test object is not saturated downstream of the grooves even when the test object has a high concentration. For this reason, the test object can be detected within a short time and the measurements can be conducted within a wide concentration range.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: September 7, 2010
    Assignee: Brother Kogyo Kabushiki Kaisha
    Inventors: Chisato Yoshimura, Hideo Nakano, Takanori Ishishika
  • Patent number: 7780860
    Abstract: An apparatus is disclosed that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: August 24, 2010
    Assignee: Biomet Biologics, LLC
    Inventors: Joel C. Higgins, Michael D. Leach, Jennifer E. Woodell-May, Brandon Miller
  • Publication number: 20100167900
    Abstract: A Microtiter plate centrifuge is disclosed. The centrifuge includes a motor assembly a shaft, extending vertically from the motor assembly, a rotor assembly, attached to the shaft, the rotor assembly including at least two slots, symmetrically positioned, with respect to the shaft and a channel corresponding to each of said slots. The channels extending from the rotor assembly are suitable for holding Microtiter plates in a vertical position. Also included is a bottom plate engaging a brake pad, which when engaged creates sufficient friction to halt rotation of the rotor assembly.
    Type: Application
    Filed: December 30, 2008
    Publication date: July 1, 2010
    Applicant: Labnet International, Inc.
    Inventors: Michael D. Rosenblum, H. Gerald Young
  • Publication number: 20090272680
    Abstract: A rotor for a centrifuge (1), wherein the rotor is rotatably driven about a rotation axis and includes two parts, i.e., a central bearing part and a waste collecting part which is provided with a waste collecting area. The waste collecting part is separable from the bearing part for waste disposal or cleaning. The bearing part and waste collecting part are provided with torque transmitting surfaces which interact with each other in a form-fitting and/or adherence manner and are connectable by axially positioning the waste collecting part on the bearing part and disconnectable by axially removing the waste collecting part from the bearing part.
    Type: Application
    Filed: April 28, 2006
    Publication date: November 5, 2009
    Inventors: Karl Grosse Wiesmann, Uwe Meinig
  • Patent number: 7527587
    Abstract: A centrifugal separator includes devices for light matter extraction and for heavy matter extraction. Each embodiment provides for a plurality, e.g., two or more stacked or layered chambers, and connected to a central compartment of the chambers is a rotating drive shaft. In the light matter extraction, a central conduit feeds fluid input into the lower chamber. An upper portion of the lower chamber communicates with the lower portion of a mid chamber via a port formed in a plate dividing the chambers. The upper portion of the mid chamber communicates with the lower portion of an upper chamber via a port formed in a plate dividing the chambers. The chambers can be fixably connected to one another. In the heavy matter extraction an initial feed conduit feeds fluid into the upper chamber.
    Type: Grant
    Filed: April 17, 2007
    Date of Patent: May 5, 2009
    Inventor: Henry J. Laughlin
  • Patent number: 7503889
    Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core wherein three separate fluid pathways are provided to allow continuous separation of biological fluids.
    Type: Grant
    Filed: April 19, 2006
    Date of Patent: March 17, 2009
    Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
  • Patent number: 7445125
    Abstract: A floating element for separating components of a physiological fluid comprises two parts that are relatively movable. The two parts define a prescribed volume between them when at their maximum separation, and one of the parts may be moved toward the other to express the fluid contained in the volume between the parts. The parts are made of materials having densities so that they assume a desired position in the fluid to allow selected components to be easily obtained are expressed.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: November 4, 2008
    Assignee: Harvest Technologies Corporation
    Inventors: James R. Ellsworth, Paul McGovern, Mark L. Kibbe
  • Patent number: 7374678
    Abstract: An apparatus that allows for separating and collecting a fraction of a sample. The apparatus, when used with a centrifuge, allows for the creation of at least three fractions in the apparatus. It also provides for a new method of extracting the buffy coat phase from a whole blood sample. A buoy system that may include a first buoy portion and a second buoy member operably interconnected may be used to form at least three fractions from a sample during a substantially single centrifugation process. Therefore, the separation of various fractions may be substantially quick and efficient.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: May 20, 2008
    Assignee: Biomet Biologics, Inc.
    Inventors: Michael Leach, Jennifer E. Woodell-May, Joel C. Higgins, Brandon Miller
  • Patent number: 7306556
    Abstract: An entrainment device for a centrifugal rotor, which is rotatable about a central rotational axis, having a number of entrainment members arranged in said space for entrainment of entering liquid in the rotation of the centrifugal rotor. The entrainment device comprises a first component, which surrounds the rotational axis and has at least one first projection, which has a radial extension, and a second component, which surrounds the rotational axis and has at least a second projection, which also has a radial extension. The second component is axially insertable in said central space to a position, in which said second projection is present adjacent to said first projection . When the entrainment devices are in place in the central space, a locking member is applicable in releasable engagement with said projection so that the second component is prevented from moving axially relative the first component.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: December 11, 2007
    Assignee: Alfa Laval Corporate AB
    Inventors: Jouko Juhani Pitkämäki, Sven-Ake Nilsson
  • Patent number: 7297272
    Abstract: A separation apparatus and method are employed using a separation channel for rotation about an axis. Such channel includes radially spaced apart inner and outer side wall portions and an end wall portion. An inlet conveys fluid into the channel. A barrier is located in the channel intermediate of the inner and outer side wall portions. A first flow path communicates between upstream and downstream sides of the barrier. A collection region may be located downstream of the barrier for communication with the first flow path. An outer side wall section of the channel may be positioned radially outward of an upstream section thereof. The barrier may join the outer side wall portion along a substantial portion of an axial length of the channel. First and second exit flow paths may allow communication with the channel either upstream or downstream of the barrier or both.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: November 20, 2007
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, Richard I. Brown, Alp Akonur
  • Patent number: 7211037
    Abstract: The present invention provides an apparatus for separating components of a fluid having an outer housing containing a core wherein three separate fluid pathways are provided to allow continuous separation of biological fluids.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: May 1, 2007
    Assignee: Therakos, Inc.
    Inventors: Dennis Briggs, Steve Gara, Tom Watters, Mike Hutchinson
  • Patent number: 7134991
    Abstract: An annular centrifugal extractor with an immersed agitation rotor. The liquid-liquid centrifugal extractor including an emulsion chamber and a settling chamber, aligned because of the addition of a section of axis to the rotor, which allows flow and operation to be regularized, especially by allowing the dimensions of the chambers to be selected more freely.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: November 14, 2006
    Assignee: Commissariat a l'Energie Atomique
    Inventors: Patrick Rivalier, Jean Duhamet, Florent Gandi
  • Patent number: 6986732
    Abstract: A centrifuge bowl has a bottom accelerator for accelerating the materials from a feed duct extending into the bowl. The accelerator is a molded body having a top plate with a central hole arranged to receive the materials from the bottom feed mouth of the duct and a plurality of vanes underneath the top plate, each vane extending generally outwardly from an inner nose underneath an outer edge of the hole to an outer end at an outer edge of the top plate. The vanes each have a bottom surface lying in an imaginary bottom surface of the molded body which is conical and contains fasteners arranged to be fastened to the conical bottom wall of the bowl. A deflector plate lies underneath the hole with a bottom surface spaced from the imaginary bottom surface and intersecting the height of the vanes.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: January 17, 2006
    Assignee: Knelson Patent Inc.
    Inventors: Edwin John William Zonneveld, Ishwinder Singh Grewal, Robert Neil Margarit, Baha Elsayed Abulnaga