Abstract: A composition comprising: an organic chemical having a chemical group having a dipole moment of at least about 1.5 Debyes and a chemical linker selected from the group consisting of carboxylic acids having 4 to 6 carbon atoms, an ethoxylated polyhydric alcohol, a polyvinyl pyrrolidone and a polyethylene glycol having a molecular weight of about 600 to about 10,000, wherein the molar ratio of organic chemical to chemical linker is about 4:1 to 1:4.

Abstract: A composition comprising: an organic chemical having a chemical group having a dipole moment of at least about 1.5 Debyes and a chemical linker selected from the group consisting of carboxylic acids having 4 to 6 carbon atoms, an ethoxylated polyhydric alcohol, a polyvinyl pyrrolidone and a polyethylene glycol having a molecular weight of about 600 to about 10,000, wherein the molar ratio of organic chemical to chemical linker is about 4:1 to 1:4.

Abstract: An aqueous composition comprising a. a skin cleansing effective amount of a surfactant or mixture thereof; b. a silicone in quantities of from about 0.1 to about 8 wt. % of the composition; c. a hydrocarbonaceous material in quantities of from about 0.1 to about 8 wt. % of the composition; d. a cationic polymer in quantities of from about 0.02 to about 1 wt. % of the composition; e.

Abstract: Thickening agents based on fatty acid monoisopropanolamide which are etherified with ethylene oxide and/or propylene oxide, their use in surface-active formulations and formulations comprising an active amount of these thickening agents.

Abstract: A skin wash composition intended for topical application to water-wetted skin comprising an .alpha.-hydroxy acid active ingredient formulated in a mild and non-irritant detergent base consisting of a mixture of a non-ionic alkylpolyglucoside surfactant and an amphoteric surfactant.

Abstract: A dry zeolite containing composition is used in a method for removing grease and/or oil stains from the human body is disclosed. In accordance with the method, zeolites having an average particle size of about 0.5 mm or less provide superior performance to remove grease and oil stains from the skin. Stain removing activities of the zeolite compositions may be enhanced by the addition of an imide.

Abstract: The invention relates to liquid cleansing compositions in lamellar phase. Use of specific anionic surfactant has been found to enhance both initial viscosity and freeze thaw (low temperature) viscosity/stability.

Abstract: The invention relates to conditioning and detergent compositions comprising, in a cosmetically acceptable medium, (A) a washing base and (B) at least one silicone comprising at least one glycerol group. The compositions can be applied for the cleansing and care of the hair or skin.

Abstract: A liquid personal cleansing composition comprising: (a) from about 1% to about 15% by weight of short chain alkyl sulphate surfactant having an average from 8 to 10 carbon atoms on the alkyl chain and mixtures thereof; (b) from about 1% to about 15% by weight of C.sub.12 to C.sub.22 alkyl ethoxy sulphate surfactant having an average degree of ethoxylation of from about 1 to about 6; (c) from about 0.1% to about 10% of water-soluble auxiliary surfactant selected from anionic surfactant other than C.sub.8 to C.sub.10 alkyl sulphate, nonionic, zwitterionic and amphoteric and mixtures thereof; and optionally (d) from about 0.01% to about 5% of cationic conditioning polymer; and (e) water; wherein the ratio of short chain alkyl sulphate to alkyl ethoxy sulphate is in the range of from about 1:3 to about 3:1, more preferably from about 2:1 to about 1:2.

Abstract: The invention discloses handwash or personal wash shampoo compositions comprising surfactant(s), cationic wheat protein and an antibacterial agent. The cationic wheat protein provides enhanced skin feel relative to other proteins.

Abstract: An aqueous cleansing and oily soil removing composition comprising a surface active agent and an agent for removing oily soil from skin, in which the surface active agent and agent for removing oily soil are separate but combinedly dispensable from a single packaging means as discrete domains, preferably in a predetermined ratio. Separating the agent for removing oily soil from the surface active agent results in improved removal of oily soil from skin, and a clean, fresh feel which is appreciated by the consumer.

Abstract: The present invention relates to a rinse-off antimicrobial cleansing composition comprising from about 0.1% to about 5.0%, by weight of the cleansing composition, of an antimicrobial active; from about 6% to about 16%, by weight of the cleansing composition, of an anionic surfactant, wherein at least about 67% of the anionic surfactant is selected from the group consisting of Class A surfactants, Class C surfactants, and mixtures thereof, wherein the ratio of Class A surfactant to Class C is from about 100:0 to about 1.5:1; from about 2% to about 4%, by weight of the cleansing composition, of a proton donating agent having a Biological Activity Index, Z, of greater than about 0.75, wherein the proton donating agent is such that the composition is essentially free of C.sub.4 -C.sub.20 alkyl fatty acid, and wherein from about 0.

Abstract: Quaternary ammonium compositions are described which are made in diluents based on vegetable oil such as soya bean oil. Such diluents remain as diluents in the final product and generally have a vapor pressure of 1 mm of Hg or less at 25.degree. C., and are liquid at ambient temperature. The liquid quaternary ammonium compound/diluent compositions have low toxicity and low volatile organic compound emission rates and high flash points, and can be tailored to particular applications. Such applications include use in fabric softeners, as cosmetics ingredients, deinking additives, surfactants, and reaction materials in the manufacture of organoclays.

Abstract: A stable, pumpable, flowable and pourable surfactant concentrate, and a method of preparation thereof, said concentrate consisting essentially of (a) at least one anionic or amphoteric surfactant, (b) at least one alkylpolyglycoside surfactant, (c) a viscosity-adjusting agent selected from the group consisting of inorganic and organic electrolytes and (d) water. The concentrate is economically shippable and easily handleable by the formulator for dilution with water, without gelation difficulties, for a variety of end-use applications with adjuvants usually associated with the desired end-use.

Abstract: A liquid personal cleansing composition comprising: (a) from about 1% to about 15% by weight of short chain alkyl sulphate surfactant having an average of from 8 to 10 carbon atoms in the alkyl chain and mixtures thereof; (b) from about 1% to about 60% by weight of water-soluble auxiliary surfactant selected from anionic surfactant other than C.sub.8 to C.sub.10 alkyl sulphate, nonionic, zwitterionic and amphoteric surfactants and mixtures thereof; (c) from about 0.01% to about 5% by weight of cationic polymeric skin conditioning agent; and (d) water. The products demonstrate excellent in-use efficacy benefits including mildness, a moisturised skin feel, excellent rinsibility and good product stability and lather attributes.

Abstract: The present invention relates to a novel structuring system comprising both xanthan gum and cross-linked polyacrylic acid polymer which combination unexpectedly has been found to provide enhanced stability for large size benefit agent droplets in an amphoteric/anionic surfactant system relative to use of either structurant alone.

Abstract: Disclosed for cleaning hard surfaces is a detergent gel containing:(a) a detergent composition without thickeners having(i) a first surfactant, wherein the first surfactant is a non-ionic glycolipid, and(ii) a second surfactant, wherein the second surfactant is a charged surfactant, wherein the ratio of the first surfactant and the second surfactant is 1:10-10:1;(b) water, wherein the detergent composition is mixed with a sufficient amount of water to induce a phase change from a liquid phase to a gel phase; and(c) one or more enzymes.

Abstract: The invention relates to the use, in cosmetic compositions for cleansing and/or removing make-up in particular from the skin, mucous membranes, eyes, and/or the hair, of at least one succinic anhydride derivative corresponding to one of the formulae I and II:GOOC--(HR)C--C(HR')--COO--(C.sub.m H.sub.2m O).sub.n --H (I)GOOC--(HR)C--C(HR')--COO--(C.sub.m H.sub.2m O).sub.n --C.sub.p H.sub.2p --O--CO--(HR')C--C(HR)--COOG (II).

Abstract: A personal cleansing composition comprising: (a) from about 1% to about 30% by weight of a dispersed oil phase comprising at least one nonocclusive liquid polyol fatty acid polyester containing at least four fatty acid ester groups wherein the polyol moiety is selected from sugars and sugar alcohols containing from about 4 to about 8 hydroxyl groups, and wherein each carboxylic acid moiety has from about 8 to about 22 carbon atoms and wherein the liquid polyol fatty acid polyester has a complete melting point of less than about 30.degree. C.; and (b) from about 5% to about 30% by weight of water-soluble surfactant selected from anionic, nonionic, zwitterionic and amphoteric surfactants and mixtures thereof. The products provide excellent in-use and efficacy benefits including excellent skin feel during and after use, good lather volume and stability characteristics, skin conditioning, mildness, stability, cleansing, good water-feel and appearance.

Abstract: A surfactant mixture containing(a) monoglyceride sulfates or monoglyceride ether sulfates, and(b) amino acid derivatives selected from(b1) acyl glutamates,(b2) vegetable protein hydrolyzates, and(b3) vegetable protein fatty acid condensates.

Abstract: A grease cutting soap based cleaning composition, for hand cleaning for example, has the following composition by weight:______________________________________ Ingredients Per Cent by Weight ______________________________________ Sodium salt fatty acid soap 20-25 Hydrogen peroxide solution (3%) 8-12 Glycerin 5-10 Cocoa butter 4-7 Citronella oil .05-1 Water to balance 100% ______________________________________The composition exhibits superior grease cutting and cleaning properties, with or without the use of additional water. The composition is mild and non-irritating to the skin.

Abstract: Aqueous, viscoelastic surfactant solutions for the cleaning of hair and skin which contain:(A) from 4 to 25% by weight of an anionic surfactant;(B) from 0 to 10% by weight of a betainic surfactant;(C) from 0 to 20% by weight of a nonionic surfactant;(D) from 0 to 6% by weight of an electrolyte;(E) from 0 to 5% by weight of a water-soluble polymer; and(F) from 0 to 5% by weight of a further constituent; in which the sum of the amounts of (A), (B), and (C) is at least 10% by weight and the sum of the amounts of (C), (D), and (E) is between 2 and 20% by weight, in each case based on the total weight of the aqueous solution, and having a shear modulus, G.sub.0, between 50 and 500 Pa at temperatures between 20 and 40.degree. C. and a pH of from 4 to 8, and in which the conditions for the identity of the storage modulus, G', and the loss modulus, G", are in the angular frequency range between 0.1 and 60 rad.multidot.s.sup.-1, exhibit optimum flow behavior for the intended applications.

Abstract: The invention relates to a process for the preparation of highly concentrated free-flowing and pumpable aqueous solutions of betaines by quaternization of a compound which contains tertiary amine nitrogen with a .omega.-halo carboxylic acid characterized in that 0.5-5% by weight of the final product, of a viscosity-reducing compound such as an alkali or alkaline earth metal citric acid salt is added to the reaction mixture before or during the quaternization reaction.

Abstract: A composition comprising: an organic chemical having a chemical group having a dipole moment of at least about 1.5 Debyes and a chemical linker selected from the group consisting of carbovlic acids having 4 to 6 carbon atoms, an ethoxylated polyhydric alcohol, a polyvinyl pyrrolidone and a polyethylene glycol having a molecular weight of about 600 to about 10,000, wherein the molar ratio of organic chemical to chemical linker is about 4:1 to 1:4.

Abstract: A personal cleansing product comprising:(a) from about 5% to about 50% by weight of a mixed surfactant system which comprises:(i) from about 1% to about 20% by weight of composition of anionic surfactant, and(ii) from about 1% to about 20% by weight of composition of amphoteric surfactant,(b) from about 3% to about 40% by weight of an insoluble nonionic oil or wax, and(c) water,wherein the anionic surfactant and amphoteric surfactant together comprise from about 5% to about 30% by weight of the composition, the weight ratio of anionic surfactant:amphoteric surfactant is in the range from about 1:5 to about 20:1, the weight ratio of total surfactant: nonionic oil or wax is in the range from about 10:1 to about 1:3, and wherein the composition is in the form of an oil-in-water emulsion having a viscosity in the range from 10,000 to 40,000 cps and a yield point of at least 50 dyne/cm.sup.2. The cleansing products demonstrate excellent lathering, mildness, stability, rinsibility and conditioning benefits.

Abstract: A personal cleansing composition comprising: (a) from about 1% to about 30% by weight of a dispersed oil phase comprising a first oil component having an oil/surfactant solution interfacial tension (IFT) of greater than about 1.0 dynes/cm and a second oil component having an oil/surfactant solution interfacial tension (IFT) in the range of from about 0.1 to about 1.0 dynes/cm; and (b) from about 5% to about 30% by weight of water-soluble surfactant selected from anionic, nonionic, zwitterionic and amphoteric surfactants and mixtures thereof; and (c) water; and wherein the ratio of first to second dispersed oil component is in the range from about 20:1 to about 1:20. The cleansing products demonstrate excellent in-use efficacy benefits including excellent skin feel during and after use, good lather volume, stability and appearance characteristics, good skin conditioning, mildness, stability, cleansing, good water feel and appearance.

Abstract: An aqueous liquid cleansing and moisturizing composition comprising a base formulation and an additive formulation in which the base formulation and additive formulation are separate but combinedly dispensable from a single packaging means in a predetermined ratio as discrete domains. By adding some surfactant to additive formulation stripe, enhanced lather is obtained. Further, some surfactant is assured, even if there is uneven pumping. Finally, greater consumer control of surfactant of moisturizer levels is afforded.

Abstract: Novel ultra-mild cold pearlizing concentrates provide pearlescent personal hair and skin compositions such as shampoos and beauty soaps with added luster and sheen.

Abstract: A cleanser composition comprising a phosphate type surfactant and an amide ether carboxylic acid as the essential components. This cleanser composition is lowly irritant to the skin etc., and excellent in lathering property, gives creamy foam in quality, and can give an excellent feeling to the skin cleansed even when it is used in hard water.

Abstract: A transparent/translucent dishwashing composition in bar/paste form containing: (a) an alkyl polyglycoside of the formula IR.sub.1 (R.sub.2 O).sub.b (Z).sub.a (I)wherein R.sub.1 is a monovalent organic radical having from about 6 to about 30 carbon atoms; R.sub.2 is divalent alkylene radical having from 2 to 4 carbon atoms; Z is a saccharide residue having 5 or 6 carbon atoms; b is a number having a value from 0 to about 12; a is a number having a value from 1 to about 6; (b) a short-chain alcohol; (c) a fatty acid; (d) an amide; and (e) a polyol.

Abstract: A liquid personal cleansing composition comprising: (a) from about 5% to about 60% by weight of water-soluble surfactant selected from anionic, nonionic and amphoteric surfactants and mixtures thereof; and (b) from about 0.01% to about 10% by weight of a hydrophobically modified nonionic cellulose ether selected from C.sub.14 -C.sub.18 alkyl and alkenyl modified, hydroxyethyl cellulose ethers having a degree of nonionic substitution in the range of from about 2.2 to about 2.8 and a degree of hydrophobic substitution in the range of from about 0.4% to about 0.6% by weight; and (c) water, and wherein the composition displays a shear stress of about 150 Pa at a shear rate in the range from about 400 s.sup.-1 to about 600 s.sup.-1 at 25.degree. C. The products demonstrate excellent in-use efficacy benefits including mildness, a moisturised skin feel, good rinsibility and good product stability.

Abstract: Foaming composition for cleaning the skin, which has the appearance of a transparent gel, including:(i) a fatty phase,(ii) at least one C.sub.5 -C.sub.7 carbohydrate fatty ester,(iii) at least one polyol,(iv) at least one foaming surfactant.

Abstract: Novel personal product and detergent compositions comprising new and known glycacarbamate, glycaurea compounds or mixtures thereof are disclosed. The personal product compositions exhibit mild cleansing, opacifying/pearlescent and suspending action. The liquid detergent compositions exhibit enhanced viscosity and improved detergency. The powdered detergent compositions exhibit improved flow characteristics and improved detergency. Also, disclosed are novel glycacarbamate and glycaurea compounds which have enhanced water solubility and do not become turbid or produce sedimentation in aqueous compositions as well as an improved method of manufacture.

Abstract: Mild aqueous detergent, e.g., shampoo, compositions are disclosed based on a mixture comprising anionic surfactant and amphoteric surfactant, such as betaines, present in the composition at a level of from about 0.75 to 1.25 parts by weight per part by weight of anionic surfactant. The compositions also contain one or a mixture of therapeutic agents such as climbazole or a mixture of climbazole and one or more co-therapeutics such as salicylic acid. The combination of mild surfactant system and therapeutic agent serve to prevent or treat mild skin disorders such as scalp itch and scalp irritation when applied to the scalp as a shampoo. Shampoo compositions also preferably contain one or more conditioning agents and suitable suspending agents.The invention also provides a method for treating dry skin comprising applying certain of the therapeutic agents to dry skin to promote the natural secretion of sebum.

Abstract: The present invention relates to aqueous-based personal wash compositions comprising hydrophobic, low viscosity (less than 1000 cp) emollient agents which have been specifically pre-thickened with defined polymer composition. Use of the specific thickeners allow incorporation of the low viscosity oil (viscosity less than 1000 cp) in the personal wash compositions to deliver enhanced skin benefits and desired user properties without compromising foaming.

Abstract: A personal cleansing product comprising: (a) from about 5% to about 50% by weight of a mixed surfactant system which comprises: (i) from about 1% to about 20% by weight of composition of anionic surfactant, and (ii) from about 1% to about 20% by weight of composition of amphoteric surfacant, (b) from about 3% to about 40% by weight of an insoluble nonionic oil or wax, and (c) water, wherein the anionic surfactant and amphoteric surfactant together comprises from about 5% to about 30% by weight of the composition, the weight ratio of anionic surfactant:amphoteric surfactant is in the range from about 1:5 to about 20:1, the weight ratio of total surfactant:nonionic oil or wax is in the range from about 10:1 to about 1:3, and wherein the composition is in the form of an oil-in-water emulsion having a viscosity in the range from 10,000 to 40,000 cps and a yield point of at least 50 dyne/cm.sup.2. The cleaning products demonstrate excellent lathering, mildness, stability, rinsibility and conditioning benefits.

Abstract: The present invention provides a cleanser composition which is free from any thickener, contains surfactant(s) at such a concentration as not to irritate the skin or mucosa, can impart an appropriate consistency to the cleanser, exhibits excellent foaming, can be easily taken out from a container in use and gives a good feel in use.The cleanser composition comprises the following components (A), (B) and (C):(A) an alkali metal salt of a secondary amide-type N-acylamino acid represented by formula (1):R.sup.1 CONH(CH.sub.2).sub.n COOH (1)wherein R.sup.1 CO represents a linear acyl group having 10 to 16 carbon atoms; and n is a number of 1 or 2;(B) an alkali metal salt of a higher fatty acid; and(C) an amphoteric surfactant; and the mixing ratio by weight of (A+B)/C ranges from 2.5/1 to 1/2.

Abstract: The invention relates to a process for making hydrogel dispersions/particles capable of trapping water insoluble beneficial agent, yet capable of disintegrating smoothly to impart desirable in use characteristics.

Abstract: An aqueous gel cleanser composition which contains:(A) from 1 to 50% by weight of a nonionic surfactant represented by the formula (1):RCOO--(CH.sub.2 CH.sub.2 O).sub.n --H (1)wherein RCO represents a saturated or unsaturated acyl group having 4 to 30 carbon atoms; and n represents a number of from 1 to 50 on the weight average;(B) from 20 to 70% by weight of a polyhydric alcohol or a glycol ether; and(C) from 0.1 to 5% by weight of a water soluble polymer.This aqueous gel cleanser composition has a high detergency on makeup stains and sebum stains, little irritates the skin, exhibits a good massaging effect and is usable even at high temperatures and humidity owing to its high stability.

Abstract: A mild, non-irriatating hair conditioning shampoo is disclosed comprising an aqueous dispersion of a water-insoluble lipid phase, an anionic hair cleansing surfactant, an amphoteric surfactant present at a level of at least about 0.75 parts by weight per part by weight of said anionic surfactant, at least one hair conditioning, film forming, polycationic polymer soluble in the aqueous dispersion and 0-6% by weight, based on the weight of the shampoo, of a water-insoluble, non-volatile hair conditioning silicone, the water-insoluble lipid phase comprising at least one lipid soluble, emulsifiable, monocationic, quaternary ammonium compound or amine solubilized in a water-insoluble long chain lipid compound, the weight ratio of monocationic compound to the lipid compound in the lipid phase being in the range of from about 5:1 to about 1:10 and the molar ratio of anionic surfactant to water-insoluble cationic compound is greater than 2:1.

Abstract: The invention relates to hydrogel dispersions/particles capable of trapping water insoluble beneficial agent, yet capable of disintegrating smoothly to impart desirable in use characteristics.

Abstract: A personal care composition in the form of an aqueous liquid comprises:i) a lipid composition comprising three components A, B and C,where A is a molecule having at least two hydrocarbon chains and a polar head group for which ##EQU1## B is a molecule having one long chain and a polar head group; and C comprises a compound capable of assisting the formation of lipid bilayers and stabilizing any lipid bilayers formed in the lipid composition; and the molar ratio of A:B:C is 1.0:1.5 to 6.0:1.1 to 8.0;ii) a surface active agent selected from anionic, nonionic, cationic, zwitterionic, amphoteric surface active agents, soap and mixtures thereof; andiii) a deposition aid.The composition may in the form of for example a shower gel or facial cleanser which is temporarily applied to the skin before being removed such as wiping or rinsing it from the skin.

Abstract: A foaming emulsion liquid composition comprisinga. an aqueous phase comprising (1) at least one high foaming anionic surfactant and (2) at least one a mild to the skin foaming surfactant selected from the group consisting of an anionic surfactant, amphoteric surfactant nonionic surfactant, or mixture thereof wherein(a) the weight ratio of a (1) to a (2) when an a (2) anionic surfactant is present is from about 10:1 to 2:1,(b) the amphoteric is present from 0 to 10 wt % of the composition, provided that if a nonionic a (2) surfactant is not present, the amphoteric surfactant is at least 1 wt % of the composition,(c) the foaming nonionic surfactant is present from 0 to 5 wt % of the composition provided that if an amphoteric a (2) surfactant is not present the foaming nonionic surfactant is at least 1 wt % of the composition, and(d) the total a surfactant is from about 12 to 30 wt % of the composition,b. an oil phase essentially insoluble in the aqueous phase present in about 3 to 15 wt % of the composition,b.

Abstract: A concentrate that is particularly useful as a pearling agent or for preparing emulsions is provided. The concentrate includes from 60 to 90% by weight of a mixture of at least one alkylglycoside of the formula RO(G).sub.x and of at least one alkylglycoside of the formula R'O(G').sub.x '. R represents a saturated or unsaturated linear or branched aliphatic radical containing from 8 to 15 carbon atoms. R' represents a saturated or unsaturated linear or branched aliphatic radical containing from 16 to 22 carbon atoms. G and G', which are identical or different, represent a saccharide residue. The subscripts x and x', which are identical or different, represent a number between 1 and 10. The concentrate also includes from 10 to 40% by weight of at least one fatty alcohol of the formula R.sub.1 OH, R.sub.1 being a saturated or unsaturated linear or branched aliphatic radical containing from 8 to 22 carbon atoms.

Abstract: An aqueous liquid cleansing and moisturising composition comprising a surface active agent selected from anionic, nonionic, zwitterionic and cationic surface active agents and mixtures thereof; an benefit agent having a weight average particle size in the range 50 to 500 microns; and a thickening agent. The thickening agent is added to the benefit agent in amount from 1 to 50% wt, based on the benefit agent.

Abstract: Novel cold pearlizing concentrates provide pearlescent personal hair and skin compositions such as shampoos and beauty soaps with added luster and sheen.

Abstract: A skin disinfecting formulation for use as a skin washing agent, comprising an alcohol, a block copolymer, a foaming surfactant, an emulsifier, a cleaning agent, a polyalkylene glycol, an emollient and water. The skin disinfecting formulation will not irritate the skin and will provide antimicrobial effectiveness to the skin.

Abstract: A method for preparing an aqueous fluid personal care composition having an anionic surfactant and a cationic surfactant and/or polymer therein which comprises:a. contacting at least about 0.2 mole % of the anionic surfactant with a charge neutralizing amount of a cationic surfactant and/or polymer in a reactor and forming an essentially chargeless complex in the reactor which is essentially free of other components of the said composition, andb. thereafter mixing the preformed complex with the remainder of the composition components.

Abstract: An aqueous liquid cleansing and moisturising composition comprising a surface active agent and a benefit agent in which the surface active agent and benefit agent are separate but combinedly dispensable from a single packaging means in a predetermined ratio as discrete domains. Separating the benefit agent from the surface active agent results in improved deposition of the benefit agent.

Abstract: A colored, soap-gelled composition, comprising an alcohol, a soap in an amount effective to gel the composition, an alkali metal bicarbonate, and an inorganic pigment. Whereas alkali metal bicarbonate deodorant compositions colored with FD & C or D & C colorants do not exhibit stable color for extended periods of time, the compositions of the present invention, using inorganic pigments, exhibit stable color for extended periods, even under accelerated, e.g., high temperature, conditions.