Zinc Patents (Class 514/494)
-
Publication number: 20140234394Abstract: An enhanced article which has a beneficial contact surface intended to allow bioabsorption of beneficial materials through the user's contact with the enhanced article in use. A functional or ornamental article which has at least one contact surface intended to come in contact with a human user includes a beneficial contact surface for covering the article's contact surface and providing a beneficial surface contact compound adapted to come in contact with a human user touching the article. The beneficial contact surface is connected to the article so that the contact surface of the article is covered by the beneficial contact surface. The presence of the beneficial surface contact compound in the beneficial contact surface means results in the exposure of the user's skin to the beneficial surface contact compound to allow absorption by the user.Type: ApplicationFiled: February 19, 2013Publication date: August 21, 2014Inventors: William A. McDonough, Aly Khalifa
-
Publication number: 20140228744Abstract: Appliances for oral use including compositions containing polymetal complexes useful in treating disorders of the oral mucosa, lips, and perioral region are described.Type: ApplicationFiled: April 16, 2014Publication date: August 14, 2014Applicant: JR CHEM, LLCInventor: Jose E. Ramirez
-
Patent number: 8802120Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.Type: GrantFiled: September 14, 2012Date of Patent: August 12, 2014Assignee: Sciessent LLCInventor: Joseph J. Crudden
-
Publication number: 20140205644Abstract: The present invention concerns antimicrobial expandable polystyrene (EPS) beads, comprising as main antimicrobial agent metal ions selected from silver and copper and combinations thereof, which antimicrobial agent(s) may be either mixed into the polymer matrix or coated onto the beads. The invention also concerns a method for producing the coated form of these antimicrobial beads.Type: ApplicationFiled: August 29, 2012Publication date: July 24, 2014Applicant: StyroChem Finland OyInventors: Jyri Nieminen, Ville Nurminen, Markus Mäki
-
Publication number: 20140205639Abstract: The present invention relates to pharmaceutical compositions suitable for the topical treatment of fungal infections of the skin and nails, such as tinea pedia and tinea cruris, among others. The active ingredients of the present compositions are low molecular weight organic acids and their salts, many of which are previously known as antifungal agents to some degree but which, when used in combination, produce a synergistic enhancement in antifungal potency such that the combined effect is greater than that when used by the agents alone. The antifungal activity of the active ingredients is further enhanced through the use of non-volatile hygroscopic solvents rather than the aqueous or volatile organic solvents used in the art.Type: ApplicationFiled: January 22, 2013Publication date: July 24, 2014Applicant: bioCEPTA CorporationInventor: Peter Mladenovich
-
Publication number: 20140199356Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.Type: ApplicationFiled: March 15, 2013Publication date: July 17, 2014Inventors: MARC CHASON, Daniel Roman Gamota, Rick Latella
-
Publication number: 20140199359Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.Type: ApplicationFiled: March 15, 2013Publication date: July 17, 2014Applicant: DMR INTERNATIONAL, INC.Inventors: MARC CHASON, DANIEL ROMAN GAMOTA, RICK LATELLA
-
Publication number: 20140199358Abstract: Described are antimicrobial polymer products made from mixtures of antimicrobial organometallic additives dispersed throughout a polymer host matrix.Type: ApplicationFiled: March 15, 2013Publication date: July 17, 2014Applicant: DMR INTERNATIONAL, INC.Inventors: MARC CHASON, Daniel Roman Gamota, Rick Latella
-
Patent number: 8778406Abstract: A composition and method which prevents or mitigates irritation on the skin of a subject by protecting against or relieving chafing, itching and moisture, and which provides a cooling sensation where applied.Type: GrantFiled: August 9, 2011Date of Patent: July 15, 2014Assignee: Joyce Labs, LLCInventors: Timothy C. Joyce, James Hammer
-
Patent number: 8778410Abstract: The present invention provides an oral or enteral composition incorporating not only BCAA but other nutrients to be conducive to comprehensive recovery from fatigue, and improvement in total physical condition. The oral or enteral composition is formulated as a composite of a branched-chain amino acid, coenzyme Q10, L-carnitine, a citric acid, and zinc.Type: GrantFiled: February 19, 2009Date of Patent: July 15, 2014Assignees: Earnest Medicine Co., Ltd., Otsuka Pharmaceutical Factory, Inc.Inventors: Takashi Higashiguchi, Takako Hatakeyama
-
Publication number: 20140193495Abstract: The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.Type: ApplicationFiled: March 13, 2014Publication date: July 10, 2014Applicant: FORWARD PHARMA A/SInventors: Henrik NILSSON, Florian SCHOENHARTING, Bernd W. MUELLER, Joseph R. ROBINSON
-
Patent number: 8759385Abstract: Hair treatment composition comprising an azole fungicide and zinc gluconate and wherein the composition does not comprise Trichogen®.Type: GrantFiled: April 13, 2010Date of Patent: June 24, 2014Assignee: Conopco Inc.Inventors: Jason Shaun Burry, Richard Livesey Evans, Graham Andrew Turner
-
Publication number: 20140171501Abstract: The invention relates to the field of medicine, and specifically to preparations for treating skin lesions, in particular viral, benign, precancerous and cancerous, non-metastasizing, dysplastic and inflammatory lesions of the visible mucous membranes, and also viral and fungal skin and nail lesions, and for correcting wrinkles and senile pigment blemishes, said preparations comprising solutions of complex compounds of salts of zinc and alpha-chlorocarboxylic acids of general formula [Zn(RCH2?xClxCOOH) (H2O)4?n]+2 .2[RCH2?x ClxCOO]?, where R=alkyl, H or Cl, x=1-2 and n=0-4, in a corresponding alpha-chlorocarboxylic acid, wherein the content of zinc in the solution is 0.25-10.0% and the content of acid is 10-90%. The preparation may additionally contain an additive perfume, for example an ethyl ester of the corresponding alpha-chlorocarboxylic acid. The treatment method consists in that 2-5 doses of the preparation, which has been precooled to 10-15° C.Type: ApplicationFiled: November 14, 2011Publication date: June 19, 2014Applicant: OBSCHESTVO S OGRANITCHENNOI OTVETSTVENNOSTJU "OXYGON"Inventors: Shalva Iosifovitch Mardi, Lev Aleksandrovich Ustynyuk
-
Patent number: 8747817Abstract: A new skin care system includes day and night skin cream compositions comprising nutrients and antioxidants for use by children between six months and eighteen years of age. The day skin cream composition provides protection from UV radiation and the night skin cream composition contains no sun protection ingredients and elevated levels of nutrients and antioxidants. A child-friendly bottle for each composition can be used by young children without difficulty. A fragrance included in each composition is popular with children, and the bottle for the day composition has graphics indicating day-time use and the bottle for the night composition has graphics indicating night-time use. The day composition is applied topically each day to the face after tooth-brushing, and the night composition is applied topically to the face each night after tooth-brushing.Type: GrantFiled: December 2, 2011Date of Patent: June 10, 2014Inventor: William Scott Prendergast
-
Publication number: 20140155365Abstract: The present invention provides compositions and methods for cytoprotection. In particular, it provides zinc chelate compositions comprising at least one zinc ion and at least one aminothiol ligand.Type: ApplicationFiled: February 6, 2014Publication date: June 5, 2014Applicant: Board of Trustees of the University of ArkansasInventor: Anne S. Martin
-
Publication number: 20140154189Abstract: The present invention, therefore, is directed to an antimicrobial compositions that decreases the bioavailability of iron by introducing a higher-affinity iron-selective chelating agent capable of competing with microbial siderophores. In one aspect, the present invention relates to an antimicrobial composition including a potentiating antimicrobial composition including one or more antimicrobial agents and a chelator having a weight ratio of the antimicrobial agent to the chelator from about 1:1000 to about 1000:1.Type: ApplicationFiled: October 14, 2013Publication date: June 5, 2014Applicant: Arch Chemicals, Inc.Inventors: George Polson, Jody Jourden, Qi Zheng, Regina M. Prioli, Diana Ciccognani, Sungmee Choi
-
Patent number: 8734837Abstract: The development and growth of oviparous species such as birds is enhanced by in ovo administration of an enteric modulator such as HMB. The enteric modulator is administered into the amnion, where it is then orally ingested by the subject. The enteric modulator enhances the enteric development of the subject prior to hatch, and enhances the growth of the animal before and after hatch.Type: GrantFiled: June 30, 2003Date of Patent: May 27, 2014Assignees: North Carolina State University, Yissum Research Development Company of the Hebrew University of JerusalemInventors: Zehava Uni, Peter R. Ferket
-
Publication number: 20140142177Abstract: A non-toxic, topical antifungal composition and use of the composition for treating infections comprising a combination of at least three or more low molecular weight, hydrophilic organic acid salts and/or derivatives exhibiting a synergistic enhancement, dissolved in a carrier, wherein the low molecular weight organic acid salts are selected from the group consisting of saturated and unsaturated, acyclic, branched and unbranched aliphatic carboxylic acids wherein the longest carbon chain has eight carbons, and aromatic carboxylic acids containing less than ten carbon atoms; the carrier comprises one or more non-aqueous, non-volatile polyhydric solvents; and wherein the combination of low molecular weight, hydrophilic organic acid salts or derivatives comprises between about 0.5% to about 50 by weight of the composition, and no single acid salt or derivative comprises more than about 75% by weight of the total acid content.Type: ApplicationFiled: November 12, 2010Publication date: May 22, 2014Inventors: Peter Mladenovich, William D. Lougheed
-
Publication number: 20140134119Abstract: Described herein are novel methods for the treatment of rosacea which include the step of applying of a composition containing a polymetal complex to an area of the skin afflicted with rosacea and novel regimens using such compounds.Type: ApplicationFiled: September 13, 2013Publication date: May 15, 2014Inventors: Joseph R. Faryniarz, Jose E. Ramirez, Hovig Ounanian
-
Publication number: 20140113004Abstract: Methods of inhibiting Barrett's esophagus and/or adenocarcinoma in a subject are provided. In a particular embodiment, the method comprises administering at least one composition comprising at least one zinc compound and at least one pharmaceutically acceptable carrier to the esophagus of the subject. The zinc may be a pharmaceutically acceptable salt of zinc, such as zinc gluconate. The zinc may be administered, for example, orally, topically, or by an implantable medical device. In a particular embodiment, the methods further comprise administering at least one analgesic, anesthetic, or other therapeutic agent or therapy for the treatment of Barrett's esophagus. The method may further comprise monitoring the progression of Barrett's esophagus in the subject.Type: ApplicationFiled: May 7, 2012Publication date: April 24, 2014Applicants: Monk Street Partners LLC, Lankenau Institute for Medical ResearchInventors: James M. Mullin, Jonathan Raines
-
Patent number: 8691726Abstract: A synergistic antimicrobial composition containing a glyphosate compound and zinc pyrithione is provided. Also provided is a method of inhibiting the growth of or controlling the growth of microorganisms in a building material by adding such a synergistic antimicrobial composition. Also provided is a coating composition containing such a synergistic antimicrobial composition, and a dry film made from such a coating composition.Type: GrantFiled: December 9, 2011Date of Patent: April 8, 2014Assignee: Dow Global Technologies LLCInventors: Emerentiana Sianawati, Sudhakar Balijepalli
-
Patent number: 8680148Abstract: Methods for treating a bacterial infection by using a metallo-desferrioxamine complex.Type: GrantFiled: August 13, 2007Date of Patent: March 25, 2014Assignees: University of Washington, Hadasit Medical Research Services and Development Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.Inventors: E. Peter Greenberg, Ehud Banin, Eyal Banin, Eduard Berenshtein, Mordechai Chevion
-
Patent number: 8664382Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.Type: GrantFiled: April 17, 2003Date of Patent: March 4, 2014Assignee: Molteni Therapeutics S.r.l.Inventors: Gabrio Roncucci, Donata Dei, Giacomo Chiti, Lia Fantetti, Francesco Giuliani, Giulio Jori, Gian Maria Rossolini
-
Publication number: 20140051754Abstract: The present invention relates to Zn N-acetyl taurinate of formula (I): [CH3—CO—NH—CH2—CH2—SO3]?2Zn2+ for the use thereof for treating prostate cancerType: ApplicationFiled: April 5, 2012Publication date: February 20, 2014Applicant: TRI-INOVInventor: Jean Pierre Durlach
-
Patent number: 8647675Abstract: Disclosed herein is an implantable medical device including an antimicrobial layer. The antimicrobial layer may include a first distinct size of silver nanoparticles, a second distinct size of silver nanoparticles, and a third distinct size of silver nanoparticles. The antimicrobial layer extends over a surface of the implantable medical device, and, in some instances, the surface of the implantable medical device may serve as a substrate on which the antimicrobial layer is deposited.Type: GrantFiled: March 8, 2012Date of Patent: February 11, 2014Assignee: Pacesetter, Inc.Inventors: Yelena Nabutovsky, Gene A. Bornzin, Annapurna Karicherla, Nirav Dalal, Prashant Dinesh, Richard Samade, John W. Poore
-
Patent number: 8647647Abstract: A topical formulation for application to exposed body tissue, the formulation comprising a silver(II) oxide and zinc oxide, intimately dispersed within a carrier medium.Type: GrantFiled: July 21, 2010Date of Patent: February 11, 2014Assignee: Aidance Skincare and Topical Solutions, LLCInventor: Perry Antelman
-
Patent number: 8647679Abstract: Disclosed herein are core-shell type zinc oxide microparticles, a dispersion containing such microparticles, and a production process and uses of the microparticles and the dispersion. As disclosed herein, the core-shell type zinc oxide microparticles have an average particle diameter of from 50 to 1,000 nm. The core is a secondary particle of spherical shape to the surface of which a polymer is attached as a shell. Methods for making the microparticles include the steps of: mixing together a zinc salt and a polymer in an organic solvent so as to obtain a mixture; and heating/refluxing the mixture at a predetermined temperature so as to cause core-shell type zinc oxide microparticles to precipitate, wherein the zinc salt is zinc acetate; and uses such as cosmetics, resins and fibers which contain the core-shell type zinc oxide microparticles and have an ultraviolet light blocking action.Type: GrantFiled: February 6, 2009Date of Patent: February 11, 2014Assignee: National Institute of Advanced Industrial Science and TechnologyInventors: Noriya Izu, Ichiro Matsubara, Toshio Itoh, Woosuck Shin, Maiko Nishibori
-
Patent number: 8642533Abstract: The present invention relates to methods of maintaining, and methods of restoring, a desired calcium homeostasis in a non-human terrestrial animal by administering an effective amount of one or more Calcium-Sensing Receptor modulators (CaSRs) to the animal. The invention further provides methods of reducing foot lesions in chickens. The invention also relates to food compositions useful in the methods of the invention.Type: GrantFiled: May 22, 2009Date of Patent: February 4, 2014Assignee: MariCal, Inc.Inventors: H. William Harris, Jr., Marlies Betka, Chris Frederick Holm, Steven Harold Jury
-
Patent number: 8637058Abstract: Composition for controlling phytopathogens comprising compound of the formula: wherein: R1 represents H, or a CO—R? acyl group; R2, the same or different when n is equal to 2, is a halogen, optionally selected from fluorine, chlorine, bromine or iodine; a C1-C9 alkyl group; a C1-C9 haloalkyl group; a C1-C9 alkoxyl group; a C1-C9 haloalkoxyl group; a C1-C9 thioalkyl group; a C1-C9 halothioalkyl group; a C3-C9 cycloalkyl group; a C2-C10 carboalkoxyl group; a cyano group; a hydroxyl group; R? represents a hydrogen; a C1-C9 alkyl group; a C1-C9 haloalkyl group; a C1-C9 alkoxyl group; a C1-C9 haloalkoxyl group; a C2-C10 carboalkoxyl group; a phenyl group; n is a number ranging from 0 to 2; X represents an oxygen atom, a nitrogen or sulfur atom in combination with a fungicide; method for controlling phytopathogens with compound of formula (1) with or without another fungicide.Type: GrantFiled: November 18, 2002Date of Patent: January 28, 2014Assignee: Isagro S.p.A.Inventors: Lucio Filippini, Marilena Gusmeroli, Alexia Elmini, Carlo Garavaglia, Luigi Mirenna
-
Publication number: 20130345061Abstract: A water-in-oil (w/o) or oil-in-water (o/w) emulsion composed of an oily phase including one or more oils of crude or refined vegetable origin, and at least one non-ionic and/or anionic emulsifying surfactant, and of an aqueous phase, the aqueous phase including at least one phyllosilicate, as a phytopharmaceutical adjuvant intended to be mixed with at least one phytopharmaceutical active agent or as a phytopharmaceutical product with mechanical action. A phytopharmaceutical composition including an active agent and also a phytopharmaceutical adjuvant as defined above, and a method of treating plants with the composition.Type: ApplicationFiled: February 9, 2012Publication date: December 26, 2013Applicant: MAXEL INDUSTRIESInventors: Roman Gerusz, Antoine Vanlaer
-
Patent number: 8592461Abstract: The present invention provides a plant disease control agent containing at least one of tetrazoyloxime dirivatives and salts thereof, and at least one selected from the group consisting of fosetyl, propamocarb, basic copper chloride, chlorothalonil, manzeb, cymoxanil, folpet, iminoctadine, cyazofamid, metalaxyl, fludioxonil, tebuconazole, prothioconazole, thiamethoxam, azoxystrobin and salts thereof.Type: GrantFiled: March 24, 2009Date of Patent: November 26, 2013Assignee: Nippon Soda Co., Ltd.Inventors: Ichirou Urihara, Atsunori Isshiki, Hiroyasu Hosokawa, Tomoyuki Saiga
-
Patent number: 8586629Abstract: This invention is based on the observed oxidative stress and increased risk on cardiovascular diseases in subjects with increased lipid peroxidation, in particular with women using oral contraceptives and in hormone replacement therapies. The invention provides compositions and combinations, particularly useful in preventing and or reducing the increased lipid peroxidation in subjects in need thereof. These compositions are based on the synergistic combination of zinc and/or a hydroxyl radical scavenger in reducing lipid peroxidation.Type: GrantFiled: August 6, 2010Date of Patent: November 19, 2013Assignee: Probiox SAInventor: Donat Eugene H. De Groote
-
Patent number: 8563538Abstract: Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of the heart muscle (for example, cardiomyopathy or myocarditis) such as idiopathic cardiomyopathy, metabolic cardiomyopathy which includes diabetic cardiomyopathy, alcoholic cardiomyopathy, drug-induced cardiomyopathy, ischemic cardiomyopathy, and hypertensive cardiomyopathy, (ii) atheromatous disorders of the major blood vessels (macrovascular disease) such as the aorta, the coronary arteries, the carotid arteries, the cerebrovascular arteries, the renal arteries, the iliac arteries, the femoral arteries, and the popliteal arteries, (iii) toxic, drug-induced, and metabolic (including hypertensive and/or diabetic disorders of small blood vessels (microvascular disease) such as the retinal arterioles, the glomerular arterioles, the vasa nervorum, cardiac arterioles, and associated capillary beds of the eye, the kidneyType: GrantFiled: February 28, 2011Date of Patent: October 22, 2013Assignee: Philera New Zealand LimitedInventors: Garth J. S. Cooper, John R. Baker
-
Patent number: 8557850Abstract: The present invention provides a plant disease control agent containing at least one of tetrazoyloxime dirivatives and salts thereof, and at least one selected from the group consisting of fosetyl, propamocarb, basic copper chloride, chlorothalonil, manzeb, cymoxanil, folpet, iminoctadine, cyazofamid, metalaxyl, fludioxonil, tebuconazole, prothioconazole, thiamethoxam, azoxystrobin and salts thereof.Type: GrantFiled: March 24, 2009Date of Patent: October 15, 2013Assignee: Nippon Soda Co., Ltd.Inventors: Ichirou Urihara, Atsunori Isshiki, Hiroyasu Hosokawa, Tomoyuki Saiga
-
Patent number: 8557293Abstract: A sunscreen composition for application for plants comprises Titanium Dioxide (TiO2), Zinc Oxide (ZnO), Silicon Dioxide (SiO2), a surfactant, wetting agent, dispersant (SWD) and water. The composition forms a suspension concentrate when combined that when diluted in water provides a solution that provides uniform coverage using convention spraying equipment. A method of protecting plants including turfgrass from ultraviolet radiation, heat stress and/or sunburn comprises combining TiO2, ZnO, SiO2, SWD and water to form a suspension concentrate. The suspension concentrate is then diluted in water and applied to an area in which sun protection is desired.Type: GrantFiled: August 26, 2010Date of Patent: October 15, 2013Inventor: Scott May
-
Publication number: 20130267483Abstract: This invention relates to complexes of certain divalent and polyvalent d-orbital metals of first transition series of the Periodic Table of Elements, from Group IV to Group VI, and including molybdenum, having a hydroxy acid [HA] and an amino acid [AA] moiety concurrently bound to a single said metal and having a spirocyclic, bidentate chelate structure of formula (I). Upon topical application said metal complexes undergo enhanced skin penetration without causing skin irritation.Type: ApplicationFiled: February 6, 2013Publication date: October 10, 2013Applicant: BIODERM RESEARCHInventor: SHYAM K GUPTA
-
Publication number: 20130210910Abstract: The present invention relates to pharmaceutical compositions suitable for the topical treatment of fungal infections of the skin and nails, such as tinea pedia and tinea cruris, among others. The active ingredients of the present compositions are low molecular weight organic acids and their salts, many of which are previously known as antifungal agents to some degree but which, when used in combination, produce a synergistic enhancement in antifungal potency such that the combined effect is greater than that when used by the agents alone. The antifungal activity of the active ingredients is further enhanced through the use of non-volatile hygroscopic solvents rather than the aqueous or volatile organic solvents used in the art.Type: ApplicationFiled: March 15, 2013Publication date: August 15, 2013Inventor: bioCEPTA Corporation
-
Patent number: 8507556Abstract: A core-shell nanoparticle having a core that includes a fluorophore and a first oxide of a first metal and a shell that includes a second oxide of a second metal such that the first oxide and the second oxide are different. Also disclosed are methods relating to the core-shell nanoparticle.Type: GrantFiled: April 4, 2011Date of Patent: August 13, 2013Assignee: Boise State UniversityInventors: Hua Wang, Denise Wingett, Kevin Feris, Mfadhusudan R. Kongara, Alex Punnoose
-
Patent number: 8491938Abstract: This invention relates to compositions comprising zinc and sulforaphane which can be used in the treatment or prevention of cancer. The invention also relates to methods of treating or preventing cancer, including prostate cancer, which comprises the administration of zinc and sulforaphane to a patient in need thereof.Type: GrantFiled: January 20, 2010Date of Patent: July 23, 2013Assignee: University of Maryland, BaltimoreInventor: Pei Feng
-
Patent number: 8491877Abstract: The present invention relates to a composition comprising an effective amount of zinc-containing layered material, an effective amount of a surfactant including a surfactant with an anionic functional group, wherein the zinc-containing layered material has a relative zinc lability of greater than about 15%. The present invention further relates to a composition according to Claim 1 wherein the composition further comprises an effective amount of a pyrithione or a polyvalent metal salt of a pyrithione.Type: GrantFiled: March 17, 2004Date of Patent: July 23, 2013Assignee: The Procter & Gamble CompanyInventors: James Robert Schwartz, Eric Scott Johnson, Bonnie Theresa King, Carl Hinz Margraf, III, Gregory V. Tormos, David Thomas Warnke
-
Publication number: 20130123355Abstract: Compositions comprising various fatty acids and their variants such as DHA, DHA-lysoPC, and EPA combined with neuro-therapeutic metal ions such as magnesium (Mg), zinc (Zn) or lithium (Li), capable of traversing the blood-brain barrier (“BBB), and blood nerve barrier (“BNB”) and methods of use of such compositions to provide therapeutic concentrations of Mg, Zn, or Li in cerebrospinal fluid over a desired period of time to a subject presenting symptoms of Mg, Zn, or Li deficiency or disease symptoms which are alleviated by supplementation of such ions are provided These symptoms may include, but are not limited to, mild cognitive impairment, bipolar disorder, stroke, and pain.Type: ApplicationFiled: November 12, 2012Publication date: May 16, 2013Inventor: Maninder Chopra
-
Patent number: 8410020Abstract: A composition comprising at least a pyridylethylbenzamide derivative of general formula (I) (a) and a compound capable of inhibiting the methionine biosynthesis (b) in a (a)/(b) weight ratio of from 0.01 to 20. A composition further comprising an additional fungicidal compound. A method for preventively or curatively combating the phytopathogenic fungi of crops by using this composition.Type: GrantFiled: February 10, 2005Date of Patent: April 2, 2013Assignee: Bayer Cropscience AGInventors: Jean-Marie Gouot, Marie-Claire Grosjean-Cournoyer
-
Publication number: 20130078318Abstract: Combined therapies and oral dosage forms based on genistein for the support of osteoporotic health.Type: ApplicationFiled: November 26, 2012Publication date: March 28, 2013Applicant: Primus Pharmaceuticals Inc.Inventors: Bruce P. Burnett, James D. Weir, Francesco Squadrito
-
Publication number: 20130045285Abstract: A method of enhancing skin hydration, the method including applying a rinse-off personal care composition comprising at least one of a zinc-containing material and a pyrithione material to non-diseased skin of an individual.Type: ApplicationFiled: August 15, 2012Publication date: February 21, 2013Inventors: Qing Stella, Jason Edward Cook
-
Publication number: 20130045284Abstract: Methods of enhancing skin hydration include applying a leave-on moisturizing composition comprising a zinc-containing material and/or a pyrithione material.Type: ApplicationFiled: August 15, 2012Publication date: February 21, 2013Inventor: Qing STELLA
-
Patent number: 8377482Abstract: The invention discloses a trace element solution, which comprises at least one metal selected from the group comprising selenium, copper, zinc, manganese and chromium; and at least one component selected from the group comprising a vitamin, a vaccine, a growth stimulant, a dewormer, iron dextran, an antibiotic and a synchronization preparation. The synchronization preparation is a combination of injectable hormonal preparations, inplantable hormonal preparations, intravaginal hormonal preparation and other slow release hormonal preparation. The antibiotics include oral, injectable and implantable theurapeutic remedies. The vaccine includes antigens and a combination of antigens and adjuvents. The growth stimulants include zeranol, estradiol, testosterone, progesterone and trenbolone acetate. The dewormer includes macrocydic lactones, leramizoles, benzimidazoles and salicylanilides. The macrocydic lactones include doramectin, ivermectin, abamectin and moxidectin.Type: GrantFiled: September 7, 2005Date of Patent: February 19, 2013Assignee: Warburton Technology LimitedInventors: Robert N. Laurie, William A. Smith
-
Patent number: 8377912Abstract: The present invention relates to a preparation suitable for the prevention and/or treatment of vascular disorders, comprising the following fractions: fraction a) consisting of long chain polyunsaturated fatty acids; fraction b) consisting of phospholipids, which fraction contains at least two different phospholipids selected from the group consisting of phosphatidylserine, phosphatidylinositol, phosphatidylcholine and phosphatidylethanolamine. fraction c) consisting of compounds which are a factor in methionine metabolism, which fraction contains at least one member selected from the group consisting of folic acid, vitamin B12, vitamin B6, magnesium and zinc.Type: GrantFiled: August 9, 2010Date of Patent: February 19, 2013Assignee: N. V. NutriciaInventors: Amanda Johanne Kiliaan, Robert Johan Joseph Hageman
-
Publication number: 20130039869Abstract: Regimen for the treatment of rosacea include the application of an anti-redness composition to at least a portion of the cleansed area of skin afflicted with rosacea. The regimen may include the application of one or more of a polymetal complex, a composition containing metronidazole, and/or a protective composition. Kits containing components useful in performing such regimens are also described.Type: ApplicationFiled: February 8, 2012Publication date: February 14, 2013Applicant: JR CHEM, LLCInventors: Jose E. Ramirez, Hovig Ounanian
-
Publication number: 20130039981Abstract: The present invention comprises a quick dissolving, long acting zinc therapeutic cold formulation containing high levels of an active compound encapsulated within bioadhesive/muco-adhesive polymers as a controlled release oral drug delivery system. The composition allows for increased residence time for enhanced prophylactic and therapeutic efficacy within the mouth and oral cavity. This allows for a reduction in the number of doses necessary to achieve therapeutic relief which will result in increased patience compliance.Type: ApplicationFiled: October 25, 2012Publication date: February 14, 2013Inventor: Subraman Rao Cherurkuri
-
Publication number: 20130035386Abstract: Certain bis[thio-hydrazide amide]-related compounds are found to be surprisingly effective at treating with leukemia, e.g., acute myeloid leukemia (AML). Methods of treating a subject with AML including administering bis[thio-hydrazide amide]-related compounds described herein, are disclosed.Type: ApplicationFiled: December 6, 2010Publication date: February 7, 2013Applicant: SYNTA PHARMACEUTICALS CORP.Inventors: Masazumi Nagai, Jianhua Shen