Nutrition Enhancement Or Support Patents (Class 514/5.5)
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Patent number: 8105584Abstract: A method of utilizing the chymotrypsin level of an individual as a measure of the success of secretin, other neuropeptides, and peptides or digestive enzyme administration to such individuals, and in particular, as a prognosticative of potential secretin, other neuropeptides, peptides, and digestive enzyme administration for persons having ADD, ADHD, Autism and other PDD related disorders. In one aspect, a method for determining the efficacy of secretin, other neuropeptides, peptides, or digestive enzymes for the treatment of an individual diagnosed with a pervasive developmental disorder (PDD) comprises obtaining a sample of feces from an individual, determining a quantitative level of chymotrypsin present in the sample, and correlating the quantitative level of chymotrypsin determined to be present in the sample with the PDD to determine the efficacy of treating the individual with secretin, other neuropeptides, peptides, or digestive enzyme administration.Type: GrantFiled: September 8, 2008Date of Patent: January 31, 2012Assignee: Curemark LLCInventor: Joan M. Fallon
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Patent number: 8097262Abstract: An enteral nutrient gel that is excellent at maintaining its solid matter (gel) form in the stomach, does not readily disintegrate or dissolve with a change in pH, is stable in its physical properties even during long-term storage, and can be passed through a feeding tube. The enteral nutrient gel contains agar, alginic acid and/or a salt thereof, soybean protein or a hydrolysate thereof, calcium, magnesium, dextrin, and, optionally, an oligosaccharide, a disaccharide and/or a monosaccharide. A solid composition containing 8 to 30 wt % protein, 2 to 25 wt % fats, and 40 to 70 wt % dextrin is used in preparing the enteral nutrient gel.Type: GrantFiled: August 31, 2007Date of Patent: January 17, 2012Assignee: En Otsuka Pharmaceutical Co., Ltd.Inventors: Minoru Kuribayashi, Yasunori Kogami
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Publication number: 20120004163Abstract: A nutritional composition for infants comprises a protein source, a lipid source and a carbohydrate source wherein the lipid source includes at least 16 wt % linoleic acid and at least 2 wt % ?-linolenic acid expressed as a percentage of total fatty acid content in each case and in amounts such that the ratio of linoleic acid:?-linolenic acid is in the range from 1 to 10.Type: ApplicationFiled: December 16, 2009Publication date: January 5, 2012Applicant: NESTEC S.A.Inventors: Catherine Mace, Olivier Kevork Aprikian, Etienne Pouteau
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Publication number: 20110319318Abstract: The present invention relates to the field of complexes. Embodiments of the present invention relate to food-grade covalent complexes containing at least one milk protein and at least one ITC-compound and to the uses of such complexes, e.g., to reduce the perceived pungency of ITC-compounds, to produce antimicrobial effects and/or to form and stabilize emulsions and/or foams.Type: ApplicationFiled: March 3, 2010Publication date: December 29, 2011Applicant: NESTEC S.A.Inventors: Koraljka Rade-Kukic, Christophe Joseph Etienne Schmitt
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Patent number: 8080520Abstract: A composition comprising heme iron and/or heme iron polypeptide in combination with ionic iron(s) and/or chelated iron(s). Administration of effective dosages of the present composition provides a method for treating and/or preventing iron deficiency anemia, and the physiological, biochemical, morphological, and behavioral manifestations symptomatic of same.Type: GrantFiled: July 20, 2009Date of Patent: December 20, 2011Inventors: Bala Venkataraman, Michael Guthrie
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Publication number: 20110305740Abstract: The present invention concerns a granulated powder comprising at least one vegetable protein and at least one starch hydrolyzate, characterized in that it has a laser volume average diameter D4,3 of between 10 ?m and 500 ?m, preferably between 50 ?m and 350 ?m, and even more preferably between 70 ?m and 250 ?m, and a dry matter content, determined after stoving at 130° C. for 2 hours, of greater than 80%, preferably greater than 85%, and even more preferably greater than 90%. The present invention also concerns process for manufacturing this granulated powder its use in various industrial field, and more particularly in the food-processing field, where it is used as a functional agent such as an emulsifying, overrun, stabilizing, thickening and/or gelling agent, in particular for totally or partially replacing certain animal proteins in the preparation of food products.Type: ApplicationFiled: February 25, 2010Publication date: December 15, 2011Applicant: ROQUETTE FRERESInventors: Bernard Boursier, Damien Passe
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Publication number: 20110288012Abstract: The present invention can provide a nutrition composition useful for patients with renal diseases, which has an effective prophylactic or improving effect for various symptoms of malnutrition, inflammation, arteriosclerosis, abnormal lipid metabolism and oxidative stress, associated with renal diseases, or for diabetic nephropathy. The nutrition composition of the present invention m contains one or more kinds of free amino acids selected from the group consisting of valine, leucine, isoleucine and histidine, and a lipid comprising ?-3 fatty acid and ?-6 fatty acid at a weight ratio (?-6 fatty acid to ?-3 fatty acid) of 0.5-5.5. In addition, the composition further contains a soybean protein or a hydrolysate thereof together with the aforementioned lipid or instead of the aforementioned lipid.Type: ApplicationFiled: June 3, 2011Publication date: November 24, 2011Applicant: AJINOMOTO CO., INC.Inventors: Shinji SOMEKAWA, Tomoyuki MINE, Naoki HAYASHI
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Publication number: 20110288011Abstract: The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood-brain barrier or into particular cell types, X is a linker, and B is a peptide therapeutic. The compounds of the invention can be used to treat any disease for which the peptide therapeutic is useful.Type: ApplicationFiled: December 7, 2009Publication date: November 24, 2011Inventors: Jean-Paul Castaigne, Michel Demeule, Catherine Gagnon, Betty Lawrence
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Publication number: 20110280954Abstract: The present invention provides compositions and methods for improving stool quality of a puppy by adjusting the balance of metabolizable cations to metabolizable anions consumed by the puppy.Type: ApplicationFiled: August 2, 2011Publication date: November 17, 2011Applicant: Hill's Pet Nutrition, Inc.Inventors: Ryan Michael Yamka, Kim Gene Friesen
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Publication number: 20110280953Abstract: The present invention provides compositions and methods for improving stool quality of a puppy by adjusting the balance of metabolizable cations to metabolizable anions consumed by the puppy.Type: ApplicationFiled: August 2, 2011Publication date: November 17, 2011Applicant: Hill's Pet Nutrition, Inc.Inventors: Ryan Michael Yamka, Kim Gene Friesen
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Publication number: 20110269678Abstract: A method of improving nutrition and/or treating low grade inflammation in an elderly human subject comprises administering to said subject a cysteine source so as to provide metabolically available cysteine in the diet of said subject in a proportion relative to all available amino acids which is greater that the proportion of cysteine relative to all amino acids which corresponds to the requirements of a healthy young human subject.Type: ApplicationFiled: July 12, 2011Publication date: November 3, 2011Applicants: INSTITUT NATIONAL RECHERCHE AGRONOMIQUE, NESTEC S.A.Inventors: Denis Breuille, Sabine Mercier, Isabelle Papet, Philippe Patureau Mirand, Christiane Obled
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Publication number: 20110257088Abstract: The present invention provides an enteral nutritional composition with which the labor of administering water between meals can be saved. The enthral nutritional composition comprises proteins, carbohydrates and lipids, with the calories per ml of the composition being less than 1 kcal and the moisture content being 30 percent by mass or more.Type: ApplicationFiled: October 27, 2009Publication date: October 20, 2011Applicant: NUTRI CO., LTD.Inventors: Susumu Kawaguchi, Yoshifumi Inoue
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Publication number: 20110238000Abstract: A hydrogel system comprising polymer-conjugated albumin molecules is provided for controlled release delivery of therapeutic agents. The polymer is a functionalized synthetic polymer, preferably PEG-diacrylate. The polymer-conjugated albumin is preferably mono-PEGylated albumin. The hydrogel system may comprise a matrix to which the polymer-conjugated albumin molecules are linked via a functional group of the polymer. The matrix may be formed from the same polymer of the polymer-albumin conjugate.Type: ApplicationFiled: December 7, 2009Publication date: September 29, 2011Applicant: TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.Inventors: Dror Seliktar, Liat Oss-Ronen
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Publication number: 20110236502Abstract: The vitamin strip is made with gel, film, or dissolvable material safe for human consumption. It can encompass all the vitamins, minerals, medicines, or meal replacement elements safe for human intake. The vitamin strip (V1) can be made as a whole or as a strip of edible dissolvable material with any vitamin(s), mineral(s), medicine(s), or meal replacement element(s) safe for human consumption on the strip of edible dissolvable material.Type: ApplicationFiled: March 29, 2010Publication date: September 29, 2011Inventor: Joseph Marcel Guillory
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Publication number: 20110230400Abstract: A nutritional composition for promoting would healing comprises a protein source, a lipid source and a carbohydrate source wherein no more than 1.8% of the total calories of the composition derive from arginine and wherein the protein source includes praline in an amount of at least 3% of the total calories of the composition. The composition may be administered orally and is particularly suitable for the amelioration of pressure ulcers although it may also be used with advantage in the nutritional management of acute wounds including pre and post surgery.Type: ApplicationFiled: May 26, 2011Publication date: September 22, 2011Inventors: Hans Smola, Gilberto Nepomuceno
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Patent number: 8012509Abstract: The present invention pertains to nutritional and pharmaceutical compositions for treating and preventing cyclooxygenase-2 mediated diseases and to a process for increasing the cyclooxygenase-2 inhibiting activity of a product. In addition thereto, the present invention relates to the use of one ore more milk protein fractions and/or one ore more milk protein preparations for inhibiting the activity of cyclooxygenase-2 (COX-2), in particular for the preparation of a medicament or a functional food for treating and preventing cyclooxygenase-2 mediated diseases.Type: GrantFiled: September 13, 2004Date of Patent: September 6, 2011Assignee: Nestec S.A.Inventors: Lionel Bovetto, Joerg Hau, Catherine Mace
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Patent number: 8012930Abstract: A therapeutic method for treating an individual diagnosed with PDD pervasive developmental disorder comprises determining the efficacy of digestive enzyme administration for the treatment of the individual based on a measure of the individual's chymotrypsin level, and administering digestive enzymes to the individual based on the determination of the measure of the individual's chymotrypsin level. A method for reducing the amount of methylphenidate (Ritalin) being taken by an individual with attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) by administering a therapeutic amount of digestive enzymes is also provided.Type: GrantFiled: March 11, 2008Date of Patent: September 6, 2011Assignee: Curemark, LLCInventor: Joan M. Fallon
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Publication number: 20110212888Abstract: This invention provides a method of improving mood and learning capacity in a mammal by giving the mammal a meal of low protein food, followed by a second meal of high glycemic index carbohydrate. A composition to be given to a mammal to improve mood and learning capacity and to reduce aggressive behavior contains at least one tyrosine uptake competitive amino acid in a ratio of 0.5% to 2% to protein. The tyrosine competitive amino acid preferred is leucine, isoleucine or valine.Type: ApplicationFiled: February 14, 2011Publication date: September 1, 2011Inventors: Valerie F. Strong, Peter Neville
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Patent number: 7989418Abstract: The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acid (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.Type: GrantFiled: October 26, 2006Date of Patent: August 2, 2011Assignee: Nestec S.A.Inventor: Norman Alan Greenberg
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Publication number: 20110183900Abstract: Compositions and methods relating to high caloric enteral formulations are disclosed herein. The invention provides a dietary composition comprising hydrolyzed soy protein and having a low viscosity and acceptable shelf life. Methods of using the dietary compositions of the invention are also disclosed.Type: ApplicationFiled: October 12, 2009Publication date: July 28, 2011Applicant: SOLAE, LLCInventors: Yadilka Maldonado, William C. Smith, Minhthy Nguyen
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Publication number: 20110136734Abstract: The present disclosure relates to preterm infant formulas comprising lutein, lycopene, and beta-carotene, and the use of the preterm infant formulas to modulate inflammation, such as skin inflammation, in preterm infants. Also disclosed are methods of modulating the level of C-reactive protein in a preterm infant using preterm infant formulas comprising mixtures of carotenoids.Type: ApplicationFiled: November 19, 2010Publication date: June 9, 2011Inventor: Bridget Barrett-Reis
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Publication number: 20110136725Abstract: There is provided a novel series of analogues of glucose-dependent insulinotropic polypeptide compounds, pharmaceutical compositions containing said compounds, and the use of said compounds as GIP-receptor agonists or antagonists for treatment of GIP-receptor mediated conditions, such as non-insulin dependent diabetes mellitus and obesity.Type: ApplicationFiled: August 7, 2009Publication date: June 9, 2011Inventor: Zheng Xin Dong
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Publication number: 20110117180Abstract: Disclosed are microcapsules with shells that are not animal by-products and methods for preparing and using such microcapsules.Type: ApplicationFiled: January 9, 2008Publication date: May 19, 2011Applicant: Ocean Nutrition Canada LimitedInventors: Cuie Yan, Wei Zhang, Yulai Jin, Lesek Alexa Demont, Colin James Barrow
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Publication number: 20110118177Abstract: The present invention relates to a process for the enzymatic production of a dipeptide composition from a cyanophycin (CGP) or CGP-like polymer preparation by degrading the polymer preparation with an CGPase, a CGPase particularly adapted for said process, and the use of cyanophycin (CGP) or CGP-like polymers or fragments thereof, notably a dipeptide composition obtained by the process as defined above, as pharmaceutical composition, medicament, or as food or feed substitute.Type: ApplicationFiled: June 15, 2009Publication date: May 19, 2011Inventors: Ahmed Sallam, Alexander Steinbüchel
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Publication number: 20110112014Abstract: Glycerol-containing solutions are useful for improving both the metabolic and hydration state of fasting individuals. The same solutions can be utilized in persons facing situations where urination is impossible or inconvenient.Type: ApplicationFiled: January 16, 2009Publication date: May 12, 2011Inventor: Stephan Lück
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Publication number: 20110077194Abstract: A method and medical composition for the treatment and/or prevention of a functional Vitamin B12 deficiency in an individual that is brought about as a consequence of oxidative stress on biochemical pathways. The functional Vitamin B12 deficiency may eventually present as dementia, other neuropsychiatric abnormality and/or vascular disease. The method involves the administration of a medical composition that supplies a cobalt-sulphur bond in the upper ?-ligand of an intracellular cobalamin molecule thereby facilitating intracellular processing of cobalamin. The cobalt-sulphur bond may he provided directly by administration of a thiolatocohalamin, such as glutathianyl-cobalamin or indirectly by the co-administration of Vitamin B12 (or a derivative thereof) with a sulphur-containing molecule, such as glutathione or a precursor thereof.Type: ApplicationFiled: February 16, 2010Publication date: March 31, 2011Inventor: Andrew McCaddon
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Publication number: 20110046048Abstract: The present invention relates in general to a shelf-stable liquid enteral composition for providing nutrition, either as a supplement, or as a complete nutrition, with a high protein content of a non-hydrolysed globular protein, in particular a whey protein.Type: ApplicationFiled: March 12, 2009Publication date: February 24, 2011Inventors: Marcel Minor, Koenraad Gerard Christoffel Weel, Natalie Elizabeth Hotrum
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Publication number: 20110028392Abstract: The invention provides an orally-administrable nutritional product comprising a dipeptide including a branched chain amino acids (BCAA). In one embodiment, the nutritional product comprises a dipeptide selected from at least one of the following: alanyl-leucine, alanyl-isoleucine, alanyl-valine, glycyl-leucine, glycyl-isoleucine, and glycyl-valine.Type: ApplicationFiled: October 8, 2010Publication date: February 3, 2011Applicant: NESTEC S.A.Inventor: Norman Alan GREENBERG
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Publication number: 20110021421Abstract: The present invention concerns liquid enteral nutritional compositions that comprise intact protein with a low specific volume allowing the preparation of nutrition with high protein and energy contents which are particularly advantageous for persons that are in, or recovering from, a disease state, persons that are malnourished or sportsmen and women and active elderly.Type: ApplicationFiled: December 5, 2008Publication date: January 27, 2011Inventors: Wynette Hermina Agnes Kiers, Marcel Minor, Thomas Hubertus Martinus Snoeren, Edward Lucian Sliwinski
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Patent number: 7855181Abstract: The subject invention provides dipeptides useful in promoting healthy muscle tissues as well as effective immune responses. The dipeptides of the subject invention are particularly advantageous because they are stable, bioavailable, and can be formulated in an aqueous solution.Type: GrantFiled: November 10, 2003Date of Patent: December 21, 2010Assignee: University of Florida Research Foundation, Inc.Inventor: Josef Neu
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Publication number: 20100317573Abstract: The present invention relates to a liquid nutritional composition for paediatric patients comprising beta-galacto-oligosaccharides, fructan, non-digestible alpha-glucan and hemicellulose.Type: ApplicationFiled: December 10, 2008Publication date: December 16, 2010Inventors: Anna Christina Goedhart, Martine Sandra Alles, Katrien Maria Jozefa Van Laere
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Publication number: 20100284980Abstract: A nutritional formula which includes a lipid or fat; a protein source; about 5 to about 100 mg/100 kcal of a source of long chain polyunsaturated fatty acids which comprises docosahexanoic acid; about 0.1 to about 1 mg/100 kcal of a prebiotic composition, wherein the prebiotic composition comprises at least 20% of an oligosaccharide which comprises galacto-oligosaccharide; and about 0.015 to about 0.1 (pg/?g) ppm of TGF-?.Type: ApplicationFiled: May 11, 2009Publication date: November 11, 2010Inventors: Francisco J. Rosales, Eric van Tol, Gyan P. Rai, Dirk Hondmann, Kirstin Morris, Dattatreya Banavara, Zeina E. Jouni, Robert J. McMahon, Deborah A. Schade, Donald Carey Walker
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Publication number: 20100273701Abstract: The present invention is directed to the use of the peptide compound Ala-lle-Phe-lle-Phe-lle-Arg-Trp-Leu-Leu-Lys-Leu-Gly-His-His-Gly-Arg-Ala-Pro-Pro-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Ala-lle-Phe-lle-Phe-lle-Arg-Trp-Leu-Leu-Lys-Leu-Gly-His-His-Gly-Arg-Ala-Pro-Pro-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.Type: ApplicationFiled: September 9, 2008Publication date: October 28, 2010Inventors: Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher
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Publication number: 20100273700Abstract: The present invention is directed to the use of the peptide compound Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.Type: ApplicationFiled: September 9, 2008Publication date: October 28, 2010Inventors: Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher
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Publication number: 20100261642Abstract: The present invention concerns high energy formulations for treatment and/or prevention of faltering growth in infants, in particular for promoting catch-up growth in a sick infant.Type: ApplicationFiled: September 17, 2008Publication date: October 14, 2010Inventors: Maarten Anne Hoijer, Johannes Wilhelmus Christina Sijben
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Publication number: 20100256043Abstract: The present invention is directed to the use of the peptide compound Glu-Ala-Leu-Glu-Leu-Ala-Arg-Gly-Ala-Ile-Phe-Gln-Ala-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Glu-Ala-Leu-Glu-Leu-Ala-Arg-Gly-Ala-Ile-Phe-Gln-Ala-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.Type: ApplicationFiled: September 9, 2008Publication date: October 7, 2010Inventors: Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher
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Publication number: 20100249019Abstract: The present invention is directed to the use of the combination of the peptide compounds Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-OH and VaI-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2 as a therapeutic combination for prophylaxis and/or treatment of cancer, a heart and vascular disease, an infectious disease, a fibrotic disease, an inflammatory disease, a neurodegenerative disease, or an autoimmune disease.Type: ApplicationFiled: September 9, 2008Publication date: September 30, 2010Inventors: Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher
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Publication number: 20100249017Abstract: The present invention is directed to the use of the peptide compound Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilisate or liquide buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys-OH optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.Type: ApplicationFiled: September 9, 2008Publication date: September 30, 2010Inventors: Dorian Bevec, Fabio Cavalli, Vera Cavalli, Gerald Bacher
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Patent number: RE42645Abstract: Nutritional or therapeutic compositions containing glutamic acid, cystine, glycine and a selenium precursor and methods for their utilization to increase glutathione synthesis and thereby enhance the immune system are described.Type: GrantFiled: March 9, 2006Date of Patent: August 23, 2011Inventor: Albert Crum