Polynitro Patents (Class 514/742)
  • Patent number: 5059603
    Abstract: A composition for treating impotence contains a vasodilator, a vasoconstrictor, and a penetration enhancing ingredient in a pharmaceutically acceptable carrier for topical application. The composition is applied topically to treat impotence.
    Type: Grant
    Filed: June 12, 1989
    Date of Patent: October 22, 1991
    Assignee: Centuries Laboratories, Inc.
    Inventor: David Rubin
  • Patent number: 5026546
    Abstract: A stabilized aqueous adjuvant suspension of dimethyl dioctadecyl ammonium bromide stabilized with at least 0.1 part by weight of a polymer of acrylic acid crosslinked with polyallyl sucrose per part by weight of dimethyl dioctadecyl ammonium bromide, plusa method of stabilizing vaccines adjuvanted with such dimethyl dioctadecyl ammonium bromide.
    Type: Grant
    Filed: December 17, 1987
    Date of Patent: June 25, 1991
    Assignee: Duphar International Research B.V.
    Inventors: Lucas A. T. Hilgers, Marinus W. Weststrate
  • Patent number: 4952401
    Abstract: A composition and a method of using the same wherein said composition comprises a rodenticide and an additive selected from the group consisting of1. polyoxyalkylated alkyl phenols;2. sorbitan fatty acids and polyoxyalkylated derivatives thereof;3. polyoxyalkylated fatty amines;4. polyoxyalkylated branched or linear alcohols, diols or polyols;5. polyoxyalkylated branched or linear mercaptans;6. polyoxyalkylated esters; and7. polyoxyalkylated amines.The composition may optionally include an organic solvent and/or a dye. The rodenticide may be selected from a wide host of compounds, including brodifacoum, bromadiolone, diphacinone, chlorodiphacinone, monofluoroacetatic acid, bromethalin, calciferol, flocoumafen, and salts of such compounds.
    Type: Grant
    Filed: June 12, 1990
    Date of Patent: August 28, 1990
    Assignee: ICI Americas Inc.
    Inventor: David G. Hobbs
  • Patent number: 4654209
    Abstract: A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on the total weight of the preparation. The composition may also contain other medicaments, the bioavailability of which is enhanced by the nitroglycerine. The action of the preparation against for example angina may be brought about by having an appropriate amount of nitroglycerine or as additional medicament another medicament active against angina. The preparation may contain an hydroxyalkylcellulose which may provide, in combination with a waxy component in the cream, for example a higher aliphatic alcohol, a prolonged release effect. The preparation has advantages particularly as regards bioavailability over prior uniphasic ointments.
    Type: Grant
    Filed: August 14, 1985
    Date of Patent: March 31, 1987
    Assignee: Euroceltique, S.A.
    Inventors: Stewart T. Leslie, Alan Rhodes, Cyril Boroda, Alfred Halpern