Abstract: Moisturizing liquid personal cleansing emulsion compositions which comprise a moisturizing phase and an aqueous cleansing phase are disclosed. The moisturizing phase comprises from about 1% to about 35% by weight of the composition of lipophilic skin moisturizing agents comprised of droplets having a particle size distribution such that at least about 10% by weight of the droplets have a diameter of at least about 500 microns. The aqueous cleansing phase comprises from about 0.1% to about 10% by weight of the composition of a stabilizer, from about 5% to about 30% by weight of the composition of a lathering surfactant, and water.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Uses of topical compositions comprising a 2-hydroxycarboxylic acid or related compound to alleviate or improve signs of skin, nail and hair changes associated with intrinsic or extrinsic aging are disclosed. 2-Hydroxycarboxylic acids and their related compounds include, for example, 2-hydroxyethanoic acid, 2-hydroxypropanoic acid, 2-methyl 2-hydroxypropanoic acid, 2-phenyl 2-hydroxyethanoic acid, 2-phenyl 2-methyl 2-hydroxyethanoic acid, 2-phenyl 3-hydroxypropanoic acid, 2,2-diphenyl 2-hydroxyethanoic acid, 2-hydroxybutane-1,4-dioic acid, 2,3-hihydroxybutane-1,4-dioic acid, 2-carboxy 2-hydroxypentane-1,5-dioic acid, 2-ketopropanoic acid, methyl 2-ketopropanoate, ethyl 2-ketopropanoate, and gluconolactone.

Abstract: Mild aqueous detergent, e.g., shampoo, compositions are disclosed based on a mixture comprising anionic surfactant and amphoteric surfactant, such as betaines, present in the composition at a level of from about 0.75 to 1.25 parts by weight per part by weight of anionic surfactant. The compositions also contain one or a mixture of therapeutic agents such as climbazole or a mixture of climbazole and one or more co-therapeutics such as salicylic acid. The combination of mild surfactant system and therapeutic agent serve to prevent or treat mild skin disorders such as scalp itch and scalp irritation when applied to the scalp as a shampoo. Shampoo compositions also preferably contain one or more conditioning agents and suitable suspending agents.The invention also provides a method for treating dry skin comprising applying certain of the therapeutic agents to dry skin to promote the natural secretion of sebum.

Abstract: The invention relates to new cosmetic compositions comprising, in an aqueous medium, at least one lipid ceramide compound and at least one peptide having at least one fatty chain. The invention also relates to an aqueous dispersion comprising a peptide having at least one fatty chain and at least one lipid ceramide compound.

Abstract: Methods for visibly reducing a skin wrinkle and for reversing the effect of aging on human facial skin involving comprising topically applying to the wrinkle and/or affected facial skin ethyl pyruvate.

Abstract: The present invention relates to leave on, oil-in-water, skin care compositions, comprising: (A) from about 0.05% to about 20% of an acidic active ingredient, preferably having a solubility parameter from about 6 to about 12; (B) from about 0.1% to about 25% of alkoxylated alcohols, alkoxylated polyols, and mixtures thereof; (C) from about 1% to about 20% of an acid stable, hydrophobic, structuring agent selected from the group consisting of saturated C.sub.16 to C.sub.30 fatty alcohols, saturated C.sub.16 to C.sub.30 fatty alcohols containing from about 1 to about 5 moles of ethylene oxide, saturated C.sub.16 to C.sub.30 diols, saturated C.sub.16 to C.sub.30 monoglycerol ethers, saturated C.sub.16 to C.sub.30 hydroxy fatty acids, and mixtures thereof, having a melting point of at least about 45.degree. C.; (D) from about 0.

Abstract: A cosmetic composition is provided which includes a C.sub.2 -C.sub.4 alpha-hydroxycarboxylic acid and a C.sub.16 -C.sub.20 alpha-hydroxycarboxylic acid delivered in a pharmaceutically acceptable carrier. Most preferred as the longer chain acids is a mixture fractionated from lanolin. The cosmetic composition can be employed in a method for treating dermatological disorders, chronoaging and environmental abuse. Preferably the composition is intended to inhibit or reduce the formation of wrinkles and sagging of skin while improving glow and firmness.

Abstract: Novel tocopherol derivatives useful for regulating skin aging and other skin disorders, as well as compositions containing the derivatives and methods for their use are described. The tocopherol derivative is tocopherol-cysteamine. Such types of skin atrophy to be treated the thinning of the epidermis and/or general degradation of the dermis often characterized by hyperplasia and structural disorganization. Such skin maladies include but are not limited to dry skin, severe dry skin, terosis, dandruff, keratoses, psoriasis, eczema, pruritus, age spots, lentigines, melasmas, wrinkles, blemished skin, hyperpigmented skin, hyperkeratotic skin, inflammatory dermatoses and age-related skin changes.

Abstract: This invention relates to a polymer-based cleanser for superficial and deep cleansing of skin.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Iminium ion scavengers are used in the invention to inhibit formation of N-nitrosamines, especially in cosmetics and pharmaceuticals formulations. The iminium ion scavengers may be used in combination with nitrite ion scavengers such as ascorbate.

Abstract: Therapeutic treatment as well as prophylactic measures are provided by topical application of compositions containing an aryl 2-acetoxyethanoic acid to eradicate or prevent the development of axillary foul odor, foot malodor and other body odors, e.g. scalp, and skin, nail and follicular infections caused by microorganisms. The compositions are antimicrobial against several organisms that infect the skin and are specifically effective against P. acnes. The compositions are therapeutically effective against folliculitis and perifolliculitis and are useful for other skin lesions, nail and mucosal infections such as impetigo, seborrheic dermatitis, erythrasma and trichomycosis axillaris, associated with or caused by microorganisms. The therapeutic effect of the composition may be synergized or amplified by incorporating a cosmetic or dermatologic agent into the formulation for topical treatment of cosmetic and dermatologic indications.

Abstract: Topical formulations comprising an anti-irritant amount of aqueous-soluble strontium (Sr.sup.2+) cation, and method for using the same to inhibit skin irritation are disclosed.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The invention discloses a gelled water/oil/water triple emulsion comprising: (A) a fatty phase comprising at least one wax having a melting point of at least 60.degree. C. and forming the primary W/O emulsion with an aqueous phase; (B) a dilution oil; (C) a gelled continuous external aqueous phase comprising at least a gelling agent having a fatty chain of the monoethylene carboxylic acid or acid anhydride copolymer type with 3 to 6 carbon atoms or a fatty chain acrylic ester. In the triple emulsion, the amount of fatty phase from the W/O emulsion is from 1 to 30% and the amount of wax having a melting point of at least 60.degree. C. is from 0.2 to 10%, based on the total weight of the triple emulsion. Said triple emulsion can be used as a carrier in cosmetic or dermatologically active compositions suitable for use on the skin or hair.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention concerns a product for topical application, capable of releasing a cosmetic and/or dermatological active ingredient in and/or on the skin, containing a lipase enzyme and at least one ester precursor of the active ingredient. The ester contains an ester functional group having a saturated or unsaturated, linear or branched chain having from 2 to 25 carbon atoms. According to a preferred embodiment, the precursor and lipase are packaged so as not to be in contact with one another until the time of application to the skin.

Abstract: A cosmetic composition comprising a hydroxy material selected from a layered double hydroxides and hydroxy salts which is suitable for treating the skin and delivering thereto the benefit agents.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Disclosed herein is an external skin-care composition comprising hydroxycarboxylic acids or derivatives thereof represented by the general formulae (1), (2), and (3), or the salts thereof: ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are each independently a hydroxyl group, an amino group or an alkoxyl group which may be substituted by 1-3 hydroxyl groups, l is a number of 7-11, m is a number of 6-10, and n is a number of 5-9. This composition exhibits an excellent moisturizing effect, moisturizes the skin, has a great effect in preventing skin roughness and shows excellent effects in enhancing the clear skin tone of the skin and reducing skin dullness, and is hence particularly useful for cosmetic skin-care compositions.

Abstract: Vitamin B12 is used to stimulate heme oxygenase production. In turn, levels of the molecules 12(R)-HETE and 12(R)-DIHETE, which are arachidonic acid derivatives, are reduced. Various topical formulations containing vitamin B12, but no other vitamins, are described.

Abstract: This disclosure relates to a method for topical use of a derivative of L-ascorbic acid which is stable, easily incorporated into cosmetically acceptable vehicles and enzymatically bioreversible in the skin to free ascorbic acid and a safe alkanol component. An exemplary embodiment uses the alkyl-2-O-L-ascorbyl-phosphate which is shown in Formula I.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: A cosmetic or dermatological composition containing a mixture of at least one type-III ceramide in the form of a single stereoisomer and of at least one type-V ceramide. This mixture is in particular a mixture having a melting point which is much lower than that of the type-III ceramide. This composition is intended in particular for moisturizing dry skins.

Abstract: Natural skin care composition containing selected hydroxylated vitamin D compounds or their glycosides, which are derived from plant sources (phytovitamins D). The plant extracts must contain a critical minimum concentration of the phytovitamin D (measured in equivalents of 1,25-(OH).sub.2 D in order to induce cell differentiation. In the alternative, phytovitamin D, especially phytovitamin D glycoside, is employed in conjunction with a plant-derived glycosidase.

Abstract: The present invention relates to a composition for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Topically applicable UVA photoprotective cosmetic/dermatological compositions comprise an effective photoprotecting amount of at least one UVA screening agent substituted by at least one optionally neutralized sulfo functional group, and an effective UVA photoprotecting-enhancing amount of at least one otherwise non-UVA photoprotecting iron chelating agent, thereby imparting a synergistic protection factor (PF) effect thereto, in a cosmetically/dermatologically acceptable topical vehicle, carrier or diluent therefor.

Abstract: The invention relates to ceramides of formula: ##STR1## where R.sub.1 denotes a C.sub.11 to C.sub.21 alkyl or alkenyl radical; R.sub.2 denotes a C.sub.11 -C.sub.19 hydrocarbon radical, which is linear and carries one or more ethylenic unsaturations, and in particular one or two, or a mixture of C.sub.11 -C.sub.19 hydrocarbon radicals, which are linear, saturated or carry one or more ethylenic unsaturations, and in particular one or two, in which the proportion of saturated radicals cannot exceed 35%, these compounds being in the form of a racemic mixture of the erythro and threo diastereoisomers in the erythro:threo proportions of 85:15 to 60:40.The invention also relates to the process for preparing the compounds as well as their applications in the cosmetic and dermopharmaceutical fields.

Abstract: A method is provided for inhibiting oil and grease generation from human skin by applying to the skin a C.sub.11 -C.sub.30 alkyl or alkenyl ester of salicylic acid as an active component in combination with a pharmaceutically acceptable carrier. Most preferred is tridecyl salicylate.

Abstract: A waterproof water-in-oil emulsion, wherein the aqueous phase consists predominately of deionized water and the oil phase includes sunscreen active ingredients, silicone emulsifiers, oil soluble solubilizers and skin conditioning agents. The emulsion provides sun protection higher than SPF 30 and is characterized in that the mean particle size of the oil phase ingredients is 2.0 Microns (.mu.). The particles of the emulsion are uniformly distributed and substantially of the same size to reduce gaps between particles thus reducing the amount of skin left exposed to ultra violet radiation. A method of manufacturing the emulsion is also disclosed.

Abstract: The present invention is directed to a lubricating and/or germicidal composition, and a method of using the composition as an antiseptic for the hands or as a disinfectant for other inanimate objects, and/or for alleviating or preventing drying of skin. The composition is an alcoholic solution containing cetyl alcohol, glycolic acid, benzalkonium chloride, and a major amount of isopropyl alcohol. In a preferred use, the composition is applied to the surface of the hands as an antiseptic film or "invisible glove" beneath a surgical or other plastic glove to inhibit microbial growth and alleviate drying of the skin.

Abstract: The present invention is directed to a method of forming an oil-in-water emulsion containing water-insoluble components, a water-soluble humectant, a weakly acidic component such as an alpha-hydroxy acid and a quaternary ammonium cationic emulsifier. The emulsion is used as a stable skin care cream.

Abstract: A oil-in-water emulsion for treating the skin comprising from about 2 to about 10 weight percent of a cationic emulsifier such as dimethyl distearyl ammonium halide, a substantially nonionizable humectant such as glycerine and a weakly acidic material having a disassociation constant of about 1 to 6. The amount of weakly acidic material is such that the pH of the finished emulsion is about 2.5 to 4.5. Also disclosed is a method of preparing the emulsion.

Abstract: The present invention relates to a method for regulating wrinkles and/or atrophy in mammalian skin comprising treating the skin with a safe and effective amount of salicylic acid and/or additional active component.

Abstract: Topical formulations comprising an anti-irritant amount of aqueous-soluble lithium (Li.sup.+) or potassium (K.sup.+) cation, and methods for using the same to inhibit skin irritation, are disclosed.

Abstract: A cyclohexanol derivative represented by the following general formula (1) and preferably the following general formula (1a): ##STR1## wherein R represents a linear or branched alkyl group having 1 to 5 carbon atoms. The above cyclohexanol derivative imparts satisfactory refrigeration to not only the mouth mucosa but also the skin. Moreover, it is practically odorless. A cool feeling and various cool feeling compositions which are practically odorless can be obtained from the cyclohexanol derivative.

Abstract: A lotion such as a sunscreen includes a pH indicator which colorizes the lotion until the lotion is applied to the human skin, whereinafter the colored lotion turns clear. A physiologically compatible pH indicator such as phenolphthalein is used which has a red appearance from pH 7.5+ and which has a clear appearance from about pH 7.0 to 7.5, the general pH range of the skin. The invention is suitable for use in any lotion, gel, mousse or medication that is best applied in an even and uniform manner to the skin. Accordingly, one preferred use of the invention is in UV-protecting sunscreens so that a user can ensure even distribution of the sunscreen on the body. In certain aspects of the invention, a cap houses the pH indicator and attaches to a container of the lotion, e.g., a sunscreen. The pH indicator mixes with the lotion as it is applied to the skin.

Abstract: An amide derivative represented by the following formula (1): ##STR1## wherein R.sup.1 represents a C.sub.1-40 hydrocarbon; R.sup.2 represents a C.sub.1-6 alkylene; R.sup.3 represents H, OH or alkoxyl; R.sup.4 represents a C.sub.1-39 hydrocarbon; R.sup.5 represents ##STR2## with the proviso that when R.sup.5 represents ##STR3## R.sup.3 does not represent OH; and a composition of the amide derivative for topical application to human skin. The composition improves the barrier function of the stratum corneum, providing improvement and prevention of dermatitis, skin roughness, or similar disorders.

Abstract: A homogeneous composition for use in cosmetics and dermatology comprises from 0.1 to 99%, preferably 0.5 to 90% by weight with respect to the total composition weight of at least one organofluorinated hydrocarbon compound or a perfluorinated carbon compound having at least one alcohol, thiol, primary of secondary amine functional group, and from 0.1 to 99%, preferably 0.5 to 70% by weight with respect to the total composition weight of at least one hydrocarbon glycol comprising two hydroxyl radicals.

Abstract: Process for the aesthetic treatment of persons who exhibit a dual character between two parts of their skin comprising a greasy area and a dry area, which comprises the application to the skin of a such person a cosmetic composition comprising an effective quantity of an emollient substance which also exhibits a lipase-inhibiting activity. The substance is selected from the group consisting of Limnanthes alba oil, Jessenia bataua oil, the unsaponifiable fraction of soya bean oil and shea butter. The effective quantity is, by weight percent of the entire composition:______________________________________ Limnanthes alba oil 0.5 to 15% Jessenia bataua oil 0.5 to 15% the unsaponifiable fraction of soya bean oil shea butter to 10%.

Abstract: A method and composition is provided for treating skin conditions including those arising from dermatologic disorders, chronoaging and environmental abuse. Non-ring esterified C.sub.11 -C.sub.30 alkyl or alkenyl esters of salicylic acid are used as the active component in combination with a pharmaceutically acceptable carrier. Most preferred is tridecyl salicylate.