Higher Fatty Acid Or Derivative Containing Patents (Class 514/943)
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Patent number: 5244925Abstract: The invention relates to emulsions intended for parenteral administration and contaning a hydrophobic phase emulsified in a an aqueous phase. In accordance with the invention, a substantial part of the hydrophobic phase contains one or more alkyl esters of pharmacologically acceptable fatty acids, and particularly their ethyl esters. The emulsions can be used for parenteral nutrient supply and as vehicles for pharmacologically active substances or agents and may also be used for both purposes in combination.Type: GrantFiled: October 8, 1991Date of Patent: September 14, 1993Assignee: Kabi Pharmacia AktiebolagInventors: Karl A. J. Wretlind, Bengt M. Ajaxon
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Patent number: 5234689Abstract: A multi-purpose, clear, anhydrous, liquid perfume composition comprising effective amounts of each of (a) one or more skin protective agents, (b) one or more skin moisturizers or emollients, (c) one or more emulsifiers, and (d) one or more perfume oils is disclosed. This composition can be used directly on the skin as a perfume, e.g., in the form of a vehicle similar to a dry oil spray, can be added directly to bath water as a perfumed bath oil, or can be mixed with water, e.g., in a jar, bottle or in situ on wet skin, to produce an emulsion body lotion.Type: GrantFiled: January 21, 1992Date of Patent: August 10, 1993Assignee: La Parfumerie, Inc.Inventors: Jerome I. Lindauer, Marcia Edwards
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Patent number: 5229422Abstract: An extemporaneous kit of pharmaceutical substance-containing fat emulsion which consists of a fat emulsion and (a) a pharmaceutical substance composition containing pharmaceutical substance and at least one solvent selected from the group consisting of water, liquid polyalkylene glycols, liquid alkylethanolamines, and liquid polyhydric alcohols, or (b) a pharmaceutical substance composition containing pharmaceutical substance and saccharides and/or 30 amino acids as an excipient, and a process for preparation of a pharmaceutical substance-containing fat emulsion therefrom.Type: GrantFiled: June 13, 1991Date of Patent: July 20, 1993Assignee: Teijin LimitedInventors: Ken Takahashi, Yuji Makino, Yoshiki Suzuki, Tatsuyuki Naruchi
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Patent number: 5229105Abstract: A skin preparation offering protection against a variety of irritants (including allergens) is prepared from an oil-in-water emulsion of the cationic type, with a fatty acid mono-ester or di-ester of triethanolamine, or a fatty acid amide of hydroxyethyl-ethylenediamine, as the cation and active barrier ingredient. The resulting emulsion binds strongly to the skin through electrostatic bonding and forms an invisible yet effective barrier that isolates the skin from adversely charged irritants, small organic compounds, irritants of high molecular weight, and irritants of alkaline pH. The skin preparation may incorporate additional active agents, such as sunscreens, antibiotics and other therapeutics, for application of these agents to the skin.Type: GrantFiled: April 6, 1992Date of Patent: July 20, 1993Assignee: Donald BasiliereInventor: Hermann Wilmsmann
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Patent number: 5221286Abstract: This invention relates to a nonionic cold mix emulsion and preparation thereof. More particularly, the present invention relates to a cosmetic composition in the form of a cream preparation which comprises a discontinuous phase dispersed in a continuous phase. The continuous phase contains water, an emulsifier, and at least one oxidizing agent. The discontinuous phase contains salts of fatty acid esters of lactylic acid, saturated monoglycerides and propylene glycol monoesters. The emulsions are particularly suitable as components of oxidizing preparations for the bleaching of hair and for the dying of hair with oxidation hair dyes and hair bleaches.Type: GrantFiled: July 17, 1992Date of Patent: June 22, 1993Assignee: Eastman Kodak CompanyInventors: A. H. Singleton, S. N. Porter
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Patent number: 5219571Abstract: A dermatological formulation or topical preparation containing fine grain bentonite and a lipophilic agent is provided to treat granuloma annulare dermatosis of the skin.Type: GrantFiled: May 13, 1992Date of Patent: June 15, 1993Inventor: Ronald D. Wise
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Patent number: 5213799Abstract: This invention refers to cosmetic compositions, particularly a skin treating preparation, comprising a transparent oil phase and a transparent aqueous phase, preferably with humectant effect, which permits a homogeneous mixture when being shaken, and which separates again in two transparent phases thereafter. These properties are achieved by the addition of 0.1 to 1.0% by weight of a C.sub.12 -C.sub.18 fatty acid triglycerol ester.Type: GrantFiled: December 5, 1991Date of Patent: May 25, 1993Assignee: Goldwell AGInventors: Stefan M. Goring, Claudia Koss
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Patent number: 5213792Abstract: Storage-stable, pearlescent hair conditioning composition consisting of 0.2 to 10 percent by weight glycerin monolauric acid ester, 0.2 to 10 percent by weight of a straight-chain fatty alcohol with 10 to 18 carbon atoms or a mixture of the fatty alcohols, 0.050 to 5 percent by weight of a quaternary compound selected from the group consisting of compounds having the general formula (I): ##STR1## and compounds having the general formula (II): ##STR2## wherein R.sub.1 is selected from the group consisting of alkyl radicals having 12 to 22 carbon atoms, cocamidoethyl, cocamidopropyl and R'--Y--, and R' is selected from the group consisting of alkyl radicals having 12 to 22 carbon atoms, and Y is --O--CO--CH.sub.2 -- or --CO--O--CH.sub.2 --CH.sub.2 --; and wherein R.sub.2 is CH.sub.3, CH.sub.2 CH.sub.2 OH or CH.sub.2 CH.sub.3, and wherein R.sub.3 is CH.sub.3, CH.sub.2 CH.sub.2 OH, benzyl or acetamidyl, and wherein X is Cl, Br, CH.sub.3 SO.sub.4, 1/2SO.sub.4, dihydrogen phosphate, acetate or acetate; 70 to 99.Type: GrantFiled: May 12, 1992Date of Patent: May 25, 1993Assignee: Wella AktiengesellschaftInventors: Karin Grundmann, Gunther Lang, Paul Gross
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Patent number: 5208012Abstract: An anti-inflammatory cosmetic composition having a large effect of absorbing and shielding all of UV-A, UV-B and UV-C, small degeneration with the passage of time even upon absorption of light, small influence upon the skin, not lowered effect of absorbing light and high stability for heat is provided. This anti-inflammatory cosmetic composition comprises 0.1 to 20% by weight of a hydroxyaryl-s-triazine compound represented by the following structural formula in a cosmetically acceptable oil carrier: ##STR1## wherein R.sub.1 and R.sub.2 represent, same or different, hydrogen atoms, chlorine atoms, hydroxyl groups, alkoxy groups of 1 to 18 carbon atoms, aryloxy groups of 6 to 8 carbon atoms or mono- or dialkylamino groups containing 1 to 4 carbon atoms and R.sub.3 and R.sub.4 represent, same or different, hydrogen atoms, chlorine atoms, alkyl groups of 1 to 8 carbon atoms, methoxy groups or ethoxy groups.Type: GrantFiled: July 31, 1991Date of Patent: May 4, 1993Assignee: Daikyo Gomu Seiko Ltd.Inventors: Mirihiro Sudo, Tomoyasu Muraki, Eiji Kawachi, Yasushi Kawachi
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Patent number: 5178871Abstract: A preferred method of producing an aqueous, stable double emulsion is disclosed. The first step of the method is the production of an "inner" emulsion. The inner emulsion is produced by combining water, a liquid hydrocarbon solvent, and an emulsifier, in an agitated mixing vessel, along with an effective amount of finely-divided particulate material, to produce an oil-in-water emulsion having a viscosity of no more than about 200,000 centipoises, wherein the finely-divided particulate material is substantially homogeneously-dispersed throughout the thus-produced oil-in-water emulsion. The second step of the method is the production of an "outer" emulsion. The outer emulsion is produced by combining a liquid hydrocarbon solvent, water, and an emulsifier, in an agitated mixing vessel, to produce a water-in-oil emulsion. The third step of the method is the production of a "dual" emulsion.Type: GrantFiled: June 26, 1991Date of Patent: January 12, 1993Assignee: S. C. Johnson & Son, Inc.Inventor: Francis L. Thill
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Patent number: 5179079Abstract: The systemic absorption after intranasal administration of certain drugs, in particular pharmacologically active polypeptides is enhanced in the presence of a phospholipid, such as a phosphatidylcholine (a lecithin), preferably admixed with a vegetable oil.Type: GrantFiled: November 27, 1991Date of Patent: January 12, 1993Assignee: Novo Nordisk A/SInventors: Philip E. Hansen, Anders R. Sorensen
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Patent number: 5143934Abstract: Controlled delivery of biologically active agents such as pharmaceuticals to body sites is accomplished by combination with a monoglyceride and a vegetable oil. Upon contact with an aqueous liquid, the composition forms a reverse hexagonal liquid crystalline phase matrix which releases the active agent in controlled fashion. The method of delivery is particularly useful for the treatment of periodontal disease by insertion of the liquid crystalline phase precursor composition directly into the periodontal pocket, where water from the gingival fluid induces the spontaneous in situ formation of the reverse hexagonal liquid crystalline phase matrix.Type: GrantFiled: October 20, 1989Date of Patent: September 1, 1992Assignee: A/S Dumex (Dumex Ltd.)Inventors: Pia Lading, Yvonne Lundsholm, Tomas Norling
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Patent number: 5143940Abstract: Ambiphilic creams with improved spreading and penetration properties as well as improved tolerance contain a glycerol-monostearate-free water-in-oil emulsifier and glycerol and/or sorbitol. Ambiphilic creams with an isopropyl myristate content have particularly favorable properties.Type: GrantFiled: December 20, 1990Date of Patent: September 1, 1992Assignee: Stada Arzneimittel AGInventors: Eberhard Nurnberg, Uwe Leonhardt, Otto P. Hornstein, Gabriele Griessmeyer, Harald Perschbacher
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Patent number: 5130122Abstract: Oral cavity and dental products are prepared by microemulsifying an adsorptive oil in an aqueous medium to produce uniform submicron sized droplets. The products avoid the generally unaesthetic, oily, and unpleasant taste problems of previous similar products.Type: GrantFiled: September 12, 1990Date of Patent: July 14, 1992Assignee: MediControl CorporationInventors: Esmail Tabibi, Arthur A. Siciliano
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Patent number: 5120527Abstract: A paramagnetic oil emulsion for magnetic resonance imaging composed of about 5 to about 30 volume percent oil and about 70 to about 95 volume percent aqueous-based paramagnetic agent carrier, at least one of the aqueous-based paramagnetic agent carrier and the oil having dissolved therein a magnetic resonance image contrast effective and less than a toxic amount of at least one soluble paramagnetic agent. The paramagnetic oil emulsion provides high intensity magnetic resonance signals in the gastrointestinal tract for MRI evaluation of the abdomen and pelvis, particularly in the distal bowel regions.Type: GrantFiled: September 19, 1990Date of Patent: June 9, 1992Inventors: King Chuen Peter Li, Peter Gwan Pa Ang
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Patent number: 5116536Abstract: The invention relates to a process for the preparation of fine-particled, stable, pharmaceutical or cosmetic dispersions consisting of an aqueous phase and an organic phase which is insoluble or not completely soluble in water (oily phase), in which a pre-emulsion is first prepared from the two phases by known emulsifying methods and is then further processed to the end product. The invention furthermore relates to apparatus for carrying out the process.Type: GrantFiled: September 13, 1990Date of Patent: May 26, 1992Assignee: Bayer AktiengesellschaftInventors: Manfred Bucheler, Hans Gehringer, Bernd Klinksiek, Bernd Koglin
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Patent number: 5114703Abstract: Injectable contrast agents of great clinical importance for lymphography, characterized by non-water soluble particle sizes between about 5 or 10 nm and about 500 or 900 nm, which have selective distribution to lymph nodes upon percutaneous administration and can be imaged with millimeter resolution. Also disclosed are methods for performing percutaneous lymphography using these contrast agents.Type: GrantFiled: May 29, 1990Date of Patent: May 19, 1992Assignee: Alliance Pharmaceutical Corp.Inventors: Gerald L. Wolf, David M. Long
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Patent number: 5110606Abstract: Palatable liquid therapeutic microemulsion wherein a drug dissolved in propylene glycol is dispersed in fatty ester. Lecithin is the emulsifier.Type: GrantFiled: November 13, 1990Date of Patent: May 5, 1992Assignee: Affinity Biotech, Inc.Inventors: Robert P. Geyer, Vinod Tuliani
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Patent number: 5106625Abstract: An oily composition comprising a dextrin fatty acid ester, a glycerol fatty acid ester having a melting point of higher than 20.degree. C., and a liquid oil is disclosed. The oily compositions for external application are transparent or semi-transparent, and possess excellent extendibility, adhesive c apability, and retentivity on the skin. The compositions are useful for various oily cosmetics and oily medicines for external application.Type: GrantFiled: August 8, 1990Date of Patent: April 21, 1992Assignee: Kao CorporationInventors: Tomoyuki Yamamoto, Akira Shigeta, Yuichiro Mitsuno
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Patent number: 5104656Abstract: To prepare an analgesic, anti-inflammatory cream, ibuprofen-S is dissolved in the PEG-7-glycerylcocoate and propylene glycol by slightly warming the solution to about 40 degrees Centigrade. Fractionated coconut oil, di-isopropyladipate, stearic acid, cetyl alcohol, polyoxyl-40-stearate, sorbitan-monostearate and propylparaben are mixed and heated to 70 degrees Centigrade. Methylparaben Sod. is dissolved in demineralized water and heated to 70 degrees Centigrade. The above oil and water phase components are mixed together, cooled to about 50 degrees Centigrade and the ibuprofen-S solution is added to the emulsion. The emulsion is homogenized and cooled to room temperature to form the cream.Type: GrantFiled: June 16, 1989Date of Patent: April 14, 1992Inventors: Pyare L. Seth, Lorne A. Campbell
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Patent number: 5104567Abstract: An environmentally acceptable cleaning liquid for use in the graphic industry consisting of 90-99% of a vegetable oil, in particular soy oil, and 1-10% of a surfactant emulsifier. The liquid is suitable for removing ink from printing machines where it is capable of replacing the traditional cleaning liquids based on petroleum spirit and aromatic solvents. As the liquid does not contain any health hazardous components it is completely safe to work with, and due to its bio-decomposable character it is disposable without problems. Because of its excellent penetration properties the liquid is also suitable for cleaning off machine parts which otherwise are difficult to clean, e.g. rubber sheets.Type: GrantFiled: March 27, 1990Date of Patent: April 14, 1992Assignee: A/S Alaska GruppenInventor: Henrik St hr
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Patent number: 5089250Abstract: The cosmetic use is described, in particular for use as a UV filter, of benzotriazole diorganopolysiloxanes having either formula: ##STR1## where R is C.sub.1 -C.sub.10 alkyl, phenyl or 3,3,3-trifluoropropyl, B is R or A, r=0-200, s=0-50, or formulas: ##STR2## where u=1-20, t=0-20 and t+u.gtoreq.3.A and/or B represent a benzotriazole C.sub.3 -C.sub.12 alkylene which may be substituted.Type: GrantFiled: February 13, 1990Date of Patent: February 18, 1992Assignee: L'OrealInventors: Serge Forestier, Gerard Lang, Herve Richard, Jean C. Grognet
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Patent number: 5089268Abstract: A sterile lipid emulsion composition made from fish oil enriched egg phosphatides; a natural oil, an osmotic agent such as glycerin and purified water, optionally adjusted to a pH of between 8.5 and 10.5 with sodium hydroxide. This composition can be administered parenterally to a host mammal.Type: GrantFiled: January 15, 1991Date of Patent: February 18, 1992Inventor: David P. Katz
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Patent number: 5080889Abstract: The following diacylglycerin is useful for a cosmetic oil and a cosmetic composition such as pack, cream and emulsion. ##STR1## (where one each of R.sub.1, R.sub.2, and R.sub.3 denotes a residue of a straight-chain saturated fatty acid having 11-17 carbon atoms, a residue of a branched-chain saturated fatty acid having 10-18 carbon atoms, and a hydrogen atom).Type: GrantFiled: March 16, 1990Date of Patent: January 14, 1992Assignee: Kao CorporationInventors: Masahiro Katada, Kenji Masui, Hisao Oomura, Yukitaka Tanaka, Mitsuo Kondo, Takashi Komori
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Patent number: 5080885Abstract: A non-toxic, brominated perfluorocarbon emulsion for internal and intravenous use in animals (including humans) is disclosed, for use as an oxygen transport medium and as a contrast enhancement medium capable of facilitating the detection of tumors and other elements within the body. This emulsion is stable and maintains its very small particle size characteristics for extended periods of time, often exceeding eighteen months after sterilization, and further may include a stabilizing component selected from the group consisting of steroids, tocopherols, cholesterols, and combinations thereof. An anti-oxidizing component enhances delivery in oxygen transport.Type: GrantFiled: August 24, 1989Date of Patent: January 14, 1992Assignee: Alliance Pharmaceutical Corp.Inventor: David M. Long, Jr.
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Patent number: 5077036Abstract: Biocompatible fluorcarbon emulsions having fluorocarbon in concentrations of from 75% weight per volume to 125% weight per volume have small, biocompatible particle size stability through heat sterilization with one emulsifying agent, including phospholipids, in concentrations of from 3% to 7% weight per volume. The single emulsifying agent can be hydrogenated lecithins and synthesized lecithins. Fluorocarbon emulsions having fluorocarbon in concentrations of from 40% weight per volume to 125% weight per volume have stability of partial pressure of oxygen and of partial pressure of carbon dioxide through heat sterilization and storage for extended periods of time after having been oxygenated with dissolved oxygen.Type: GrantFiled: March 30, 1990Date of Patent: December 31, 1991Assignee: Alliance Pharmaceutical Corp.Inventor: David M. Long, Jr.
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Patent number: 5064636Abstract: A paramagnetic oil emulsion for enteric administration composed of about 5 to about 30 volume percent oil and about 70 to about 95 volume percent aqueous-based paramagnetic carrier, the aqueous-based paramagnetic carrier having a magnetic resonance contrast effective and less than a toxic amount of at least one water-soluble paramagnetic agent. The paramagetic oil emulsion provides high intensity magnetic resonance signals in the gastro-intestional tract for MRI evaluation of the abdomen and pelvis.Type: GrantFiled: October 19, 1989Date of Patent: November 12, 1991Inventors: King C. P. Li, Peter G. P. Ang
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Patent number: 5059626Abstract: A one phase, liquid composition for oral administration comprises a NSAID such as an anthranilic acid derivative plus a di- or triglyceride of a medium chain fatty acid edible oil which has the characteristics of a pharmaceutical solvent carrier as known to those skilled in the art. Other pharmaceutical additives may be optionally added. An additional stipulation is that ethanol or other monohydric alcohol solvents should not be present.Type: GrantFiled: January 30, 1991Date of Patent: October 22, 1991Assignee: Applied Analytical Industries, Inc.Inventors: Moo W. Park, Henry C. Caldwell
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Patent number: 5047396Abstract: The present invention relates to an intravenous pharmaceutical composition comprising cyclosporin as active ingredient. The composition is composed ofa) 1 part by mass of one or more cyclosporins,b) 8 to 13 parts by mass of a monoester of a saturated hydroxylated fatty acid formed with polyethylene glycol or the mixture of said monoesters,c) 4 to 10 parts by mass of one or more intravenously administerable mono- or polivalent alcohols.The invention further relates to a process for preparing such composition.Type: GrantFiled: July 21, 1989Date of Patent: September 10, 1991Assignee: Biogal GyogyszergyarInventors: Erno Orban, Tibor Balogh, Lajos Ila, Gabor Ambrus, Antonia Jekkel, Sandor Elek, Eva Tomori, Istvan Elekes, Eva T. Sarudy, Imre Moravcsik, Lajos Siklosi
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Patent number: 5019376Abstract: This invention relates to cationic oil-in water emulsion compositions which are especially useful as hair conditioning compositions which have a sparkling pearlescent appearance due to the presence of irregular platelet-like crystals suspended in the composition. The compositions comprise a cationic water-in-oil emulsion of from (a) about 0.1% to 5%, preferably from 0.1 to 0.8%, of a quaternary ammonium compound such as stearyl dimethyl benzyl ammonium chloride; (b) about 1-10%, preferably 1-2%, of a fatty acid having 12-16 carbon atoms such as myristic acid and a fatty monoalcohol having from 12 to 18 carbon atoms such as cetyl alcohol in a 70:30 to 95:5, preferably 75;25 to 85:15, weight ratio of acid to alcohol; (c) about 0.Type: GrantFiled: October 22, 1990Date of Patent: May 28, 1991Assignee: S. C. Johnson & Son, Inc.Inventor: Heidi J. Uick
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Patent number: 5017605Abstract: A cosmetic preparation consists essentially of a mixture of a stable oil/water emulsion of cosmetically acceptable ingredients and a stable water/oil emulsion of cosmetically acceptable ingredients. The new preparation is prepared by mixing the two original emulsions such that a superfinely dispersed product is obtained. The particle size of the inner phases of the emulsions is 2-50 .mu.m. The preparation provides needed ingredients such as fats or moisture to skin of varying types. An example of the cosmetic preparation is a cream containing jojoba oil.Type: GrantFiled: August 3, 1989Date of Patent: May 21, 1991Assignee: Schering Wien Ges. m.b.H.Inventor: Wolfgang Stindl
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Patent number: 5010067Abstract: An injectable pharmaceutical mixture comprises:(A) a water-oil emulsion vehicle comprising:(a) about 5 to 25% fatty acid triglycerides;(b) sufficient physiologically acceptable emulsifying agent, e.g. from about 0 to 1.2% egg phosphatides, purified; andthe balance water, with sufficient alkali metal hydroxide added to adjust to an alkaline pH: and(B) an active ingredient which is a PAF receptor inhibitor or anti-tumor agent, which is an ether or carbamoyl phospholipid salt.Type: GrantFiled: July 19, 1988Date of Patent: April 23, 1991Assignee: Sandoz Pharmaceuticals Corp.Inventors: Dean A. Handley, William J. Houlihan, David B. Weinstein
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Patent number: 5002974Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: March 26, 1991Assignee: Warner-Lambert Co.Inventor: Navin M. Geria
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Patent number: 5002760Abstract: A skin care composition to prevent premature photoaging of the skin of the user includes in addition to basic ingredients, in combination, retinol, a UV absorber and a moisturizer.Type: GrantFiled: October 2, 1989Date of Patent: March 26, 1991Inventor: Phillip K. Katzev
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Patent number: 4997819Abstract: The invention is a fatty emulsion stabilized by a polysaccharide derivative, wherein the fatty emulsion contains a polysaccharide derivative which is substituted by a fatty acid or cholesterol at a proportion of 0.5-5 per 100 of sugar units.Type: GrantFiled: November 21, 1989Date of Patent: March 5, 1991Assignee: Nippon Oil & Fats Co., Ltd.Inventors: Shigehiko Yamaguchi, Junzo Sunamoto
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Patent number: 4996239Abstract: A skin protective composition for exhibiting enhanced water repellency and conditioning effects containing aliphatic waxes and hydrophobic silicones in a nonallergenic, non-toxic, cosmetically acceptable carrier. The composition is useful to protect mammals from solar radiation and in the treatment of diaper rash.Type: GrantFiled: September 16, 1988Date of Patent: February 26, 1991Assignee: Neutrogena CorporationInventor: Peter Matravers
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Patent number: 4996004Abstract: The invention relates to a process for the preparation of fine-particled, stable, pharmaceutical or cosmetic dispersions consisting of an aqueous phase and an organic phase which is insoluble or not completely soluble in water (oily phase) in which a pre-emulsion is prepared from the two phases by known emulsifying methods and in then pumped through a jet disperser, the temperature, the proportion of the aqueous and organic phases, and the pressure at the jet disperser being adjusted so that phase inversion of the emulsion is effected in the jet disperser at the same time as homogenization and fine dispersion, and in the course of which all the pressure energy is consumed in the dispersing zone and the dispersion leaves as a non-directional stream.Type: GrantFiled: March 15, 1989Date of Patent: February 26, 1991Assignee: Bayer AktiengesellschaftInventors: Manfred Bucheler, Hans Gehringer, Bernd Klinksiek, Bernd Koglin
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Patent number: 4992478Abstract: A long lasting, esthetically pleasing medicated skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65%;(3) an effective amount of a topical medicament; wherein the medicament is a corticosteroid and the oil phase is added to the aqueous phase to form an emulsion and a topical medicament admixed into the emulsion has been developed.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992477Abstract: A long lasting, esthetically pleasing skin care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed. The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4992476Abstract: A long lasting, esthetically pleasing skin cleansing and care moisturizing composition comprising(1) an oil phase comprising oil from about 30% to about 80% and a non-ionic surface active agent having an HLB number of about 7 to about 12, wherein the non-ionic surface active agent is present in an amount of about 5% to about 9%;(2) an aqueous phase comprising an aqueous thickening agent from about 0.05% to about 5% and water from about 15% to about 65% wherein the oil phase is added to the aqueous phase to form an emulsion has been developed,(3) an effective amount of an abrasive to remove oily deposits, cosmetics and particulates from the skin surface.The method of preparation of the composition and a method of treating skin with the composition are also disclosed.Type: GrantFiled: April 4, 1988Date of Patent: February 12, 1991Assignee: Warner-Lambert CompanyInventor: Navin M. Geria
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Patent number: 4990501Abstract: A composition for application to human and animal tissue surfaces, said composition comprising an aqueous medium and a film-forming component at least partially soluble or dispersible in said aqueous medium, said film-forming component comprising an ester or mixture of esters, at least one being an ester of a polyol.Type: GrantFiled: March 26, 1987Date of Patent: February 5, 1991Assignee: Sempernova PLCInventors: Frazer K. E. Imrie, Ken James
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Patent number: 4985250Abstract: The invention provides a water/oil/water duplex emulsion in which the external continuous phase is gelled. This gelling is obtained by having an osmotic pressure component, e.g. an electrolyte, in the internal aqueous phase which draws water from the external phase through the oil phase. The structure is firm but contains a considerable volume of available aqueous phase. The structure is of value in e.g. foods and cosmetics.Type: GrantFiled: June 5, 1989Date of Patent: January 15, 1991Assignee: Unilever Patent Holdings B.V.Inventors: Rodney D. Bee, Ian D. Evans, Martin J. Izzard
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Patent number: 4980084Abstract: A water rinsable petroleum jelly formulation, which is a water-in-oil preferably translucent emulsion, is described which comprises an aqueous phase containing a humectant, as a preferable component, and a surface active detergent effective to confer rinsable characteristics on the emulsion, an oil phase comprising a petroleum jelly component, and a water-in-oil emulsifying agent.Type: GrantFiled: October 5, 1988Date of Patent: December 25, 1990Assignee: Chesebrough-Pond's USA Co., division of CONOPCO, INC.Inventors: Mohan Vishnupad, Jose E. Ramirez, Thomas M. Deppert
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Patent number: 4971788Abstract: Oral cavity and dental products are prepared by microemulsifying an adsorptive oil in an aqueous mediun to produce uniform submicron sized droplets. The products avoid the generally unaesthetic, oily, and unpleasant taste problems of previous similar products.Type: GrantFiled: January 27, 1989Date of Patent: November 20, 1990Assignee: MediControl CorporationInventors: Esmail Tabibi, Arthur A. Siciliano
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Patent number: 4946832Abstract: Cosmetic Base composition exhibiting therapeutic properties comprising an acyl fatty acid alpha-hydroxy carboxylic acid ester or alkali metal salt thereof, a sucrose fatty acid ester, and a solvent.Type: GrantFiled: July 21, 1988Date of Patent: August 7, 1990Assignee: R.I.T.A. CorporationInventors: Stephen T. Goode, Robert R. Linton, Fred Baiocchi
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Patent number: 4940577Abstract: A cosmetic composition comprising an ester containing emulsion, an emulsifier having the empirical formula ##STR1## and a minor amount of water. The composition is a clear, water-in-ester microemulsion having the feel of mineral oil. Sunscreen additives and other active cosmetic ingredients can be incorporated into the blend.Type: GrantFiled: April 25, 1988Date of Patent: July 10, 1990Assignee: Lipo Chemicals Inc.Inventors: Stephen M. Greenberg, Louis A. Frischling
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Patent number: 4931210Abstract: The present invention relates to a process for producing a W/O/W type multiple emulsion using a polyglycerol polyricinolate (i.e. a polyglycerol ester of a polycondensed fatty acid of castor oil).The use of the polyglycerol polyricinolate is effective in increasing the rate of formation of the W/O/W type multiple emulsion remarkably and giving a W/O/W type multiple emulsion which is stable over a long period of time. The W/O/W type multiple emulsion has also an excellent heat stability and is useful for the production of medicines and cosmetics.Type: GrantFiled: September 19, 1988Date of Patent: June 5, 1990Assignee: Menji Milk Products Company LimitedInventors: Yasuyuki Takahashi, Toshiro Yoshida, Takeshi Takahashi
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Patent number: 4929439Abstract: Cosmetic screening composition in the form of an oil-in-water emulsion comprising a UV-A screening compound and a UV-B screening compound and its use for the protection of the skin against ultraviolet radiation.The invention relates to a cosmetic composition in the form of an oil-in-water emulsion which screens out UV rays of wavelengths of between 280 and 400 nm, which comprises partially or completely neutralized benzene-[1,4-bis(3-methylidenecamphomethylsulphonic acid)], in combination with N-(2-ethylhexyl)-4-(3-methylidenecamphor)benzenesulphonamide.The sun protection composition of this kind possesses a high index of protection, enabling it to be used on skins that are very sensitive or continually exposed to solar radiation.Type: GrantFiled: February 4, 1988Date of Patent: May 29, 1990Assignee: L'OrealInventors: Jean Cotteret, Jean F. Grollier
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Patent number: 4920098Abstract: A method is provided for individuals under treatment for or at risk of atherosclerotic, vascular, cardiovascular, and/or thrombotic disease by administering a composition which comprises a protein source; a carbohydrate source; and at least one lipid selected from the group consisting of: gamma-linolenic acid; eicosapentaenoic acid; docosahexaenoic acid; sterodonic acid; and linolenic acid. Both an enteral and parenteral composition are provided.Type: GrantFiled: August 28, 1989Date of Patent: April 24, 1990Assignee: Baxter International Inc.Inventors: Richard Cotter, Robert C. Johnson, Michael Ward, David C. Madsen, Anthony J. Valicenti, Michael P. Menard, Hugh N. Tucker
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Patent number: 4883659Abstract: A water resistant, non-gummy hygroscopic, flexible and pliable thin film of 2-hydroxyethyl methacrylate homopolymer deposited on an epidermal surface, a stable emulsion from which the film can be made and a special process for the manufacture of the stable emulsion, utilizing an ammonium salt of a long chain fatty acid as an emulsifying agent therein. The topical application of stable emulsions utilizing an ammonium salt of a long chain fatty acid as an emulsifying agent therein, from which a water resistant, non-gummy, hygoscopic, flexible and pliable thin film of 2-hydroxyethyl methacrylate homopolymer is deposited on an epidermal surface. Special solvent combinations and emulsification techniques are described.Type: GrantFiled: August 24, 1988Date of Patent: November 28, 1989Assignee: Dento-Med Industries, Inc.Inventors: Jack J. Goodman, Harvey S. Tauman, Charles Fox, Thomas J. Hart