Abstract: The invention consists of a method for manufacturing an aqueous formulation containing at least one oil, and comprising the steps of mixing at least one associative polymer, one oil, and water, encapsulating the oil by increasing the pH to a value greater than 8, potentially precipitating the mixture by reducing the pH to a value less than 6, and potentially isolating the resulting particles by removing the water. The aqueous formulations, as with the aqueous dispersions, and the resulting solid particles constitute other objects of the invention.

Abstract: The present invention relates to a composition comprising a hydrogel polymer having less than 100% haze, and distributed therein an oxygen enhancing effective amount of oxygen permeable particles having an oxygen permeability of at least about 100 barrer, average particle size less than about 5000 nm.

Abstract: Generally silicone materials adapted to releasably adhere to human skin don't attach readily to substrates such as fibrous substrates (e.g., woven and nonwoven webs), films, plastic, etc. Disclosed are inventive blends of low-tack materials, such as a low-tack silicone material, and a high-tack silicone material, such as a high-tack, hot-melt, silicone adhesive, that both releasably adhere to skin and join to various substrates, including fibrous substrates. Furthermore, these same blends may be disposed between, and attached to, a silicone adhesive layer and a substrate. In other words, the disclosed silicone blends may be used to join a silicone adhesive layer to a substrate.

Abstract: This invention relates to a coupling liquid for ultrasound devices, preferably high intensity focused ultrasound (HIFU). The coupling liquid comprises a liquid aqueous solution of at least one hydrophilic polymer having an average molecular mass of between 30,000 and 70,000 and at least one alcohol with a carbon chain of 1 to 7 carbon atoms. Also disclosed is a container (10) for an ultrasound coupling liquid having a thin wall.

Abstract: A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C5-C42)alkyl-polyether radical per molecule, wherein the bicycloheptyl- or bicycloheptenyl-polyether radical may optionally be substituted on one or more of the ring carbon atoms by one or two (C1-C6)alkyl groups per ring carbon atom is useful in making polymers, particularly pH responsive polymers.

Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.

Abstract: Improved composition of a fixing cream, in particular for tooth prostheses, containing at least one oil and/or fat, preferably of a plant type, at least one water-soluble polymer selected from the group of cellulose derivatives, at least one alkyl vinyl ether/maleic acid anhydride copolymer, the fatty acid content of the plant oil or fat contained consisting of at least 20% by weight of unsaturated fatty acids.

Abstract: Provided herein is a film-forming composition for use in the preparation of a soft capsule, which comprises (a) acid-decomposed waxy corn starch; (b) a gelling agent; and (c) a plasticizer. A soft capsule comprising a shell produced using the film-forming composition disclosed herein has excellent characteristic properties with respect to physical strength, disintegration ability, odor, taste, color and lack of adhesion and also exhibits excellent stability with time.

Abstract: An implantable orthopedic medical device is disclosed. The medical devices is formed from a biodegradable polymer stereocomplex comprising a biodegradable polymer including a first enantiomer and a second enantiomer, wherein the implantable medical device initially degrades at a first degradation rate and subsequently degrades at a second degradation rate that is faster than the first degradation rate.

Abstract: A polymer composite composition wherein at least one of the constituents is a silicone ionomer and the other constituent is polymer.

Abstract: A method and a device for effecting the cordless retraction of the gingival sulcus tissue that includes a dam shaped to be fitted onto a tooth. In one embodiment, the well of the dam is pre-filled with a predetermined amount of a flowable retraction material having a heavy viscosity or putty consistency. In another embodiment a hydrophilic material is added. The preloaded tooth dam is fitted to a prepared tooth so that when pressure is applied onto the tooth dam, the retraction material is displaced under pressure and forced into the sulcus, causing the gingival tissue to retract away from the tooth to enlarge the gingival sulcus. In another embodiment the cap is filled with a dilatant material. In another embodiment, the cap is filled with an impregnated compressible porous material. In yet another embodiment, the cap is pre-dosed with an astringent or hemostatic agent.

Abstract: Method of producing a thermoplastic polyurethane having a light stabilization useful for ophthalmic applications, comprising combining precursors of a polyurethane and at least one antioxidant, and incorporating therein, either before, during or after polymerization, at least one light stabilizer, said method being characterized in that the antioxidant is benzenepropanoic acid, 3(1,1-dimethylethyl)-4-hydroxy-5-methyl-1,1?-[1,2-ethanediylbis(oxy-2,1-ethanediyl)]ester and the light stabilizer is bis(1,2,2,6,6-pentamethyl-4-piperidinyl)-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methyl]butylmalonate together with at least one additional component chosen from among phenol, 2-(5-chloro-2H-benzotriazole-2-yl)-6-(1,1-dimethylethyl)-4-methyl and 2,2?-methylenebis(6-(2H-benzotriazol-2-yl)-4-1,1,3,3-tetramethylbutyl)phenol).

Abstract: The present disclosure provides a brush polymer, including: a linear polymer main chain; and brush structural side chains, including: a hydrophobic molecular branch, and a hydrophilic molecular branch and/or an anti-biofilm/or an anti-microbial molecular branch, wherein the linear polymer main chain is conjugated to the side chains by covalent bonds formed between a hydroxyl group and a reactive functional group, wherein the reactive functional group includes: isocyanate, carboxyl, or epoxy. The present disclosure also provides a medical application of the brush polymer.

Abstract: This invention relates to the fields of polymer chemistry, materials science and ophthalmology. More particularly it relates to optical components and method(s) of preparing same from hydrophobic acrylic (HA) monomer(s) that exhibit reduced or eliminated glistenings when implanted in a patient's eye. The method of this invention uses a mixture of one or more low temperature initiators (LTI) combined with one or more high temperature initiators (HTI), to polymerize one or more HA monomers to produce an optical HA polymer which, when used to manufacture an optical component and implanted as with an intraocular lens (IOL), exhibit reduced glistenings to the patient.

Abstract: The invention relates to a composition for injectable cement, comprising a mineral sold phase, a separate liquid phase and, optionally, microparticles of a biocompatible and biodegradable polymer. The mineral solid phase comprises a mixture of powders with the molar composition: (CP)6 (CaO)y (SrCO3)z, [CP being CaHPO42H2O, CaHPO4, Ca1-xSrxHPO4, an equimolar mixture of bis(Ca(H2PO4)2, H2O and CaO, or a mixture of two or three of said compounds] and y+z=4?1. The liquid phase comprises pure apyrogeneic water or a saline aqueous solution with pH 4 to 9. The ratio L/P [volume of liquid phase/mass of solid mineral phase] is at least 0.4 ml/g. The above is of application as bone replacement.

Abstract: The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a phospholipid into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the phospholipids.

Abstract: The present invention provides a composition for crown material including resin and a fine spherized composite glass powder. The fine composite glass powder of the present invention for such a configuration has superior qualities with regard to both sintering and optical characteristics, and can be used as a filler for crown material.

Abstract: Presently described are methods of intra-oral scanning and an aqueous dental compositions suitable for use for scanning comprising an aqueous solution of a polymer, wherein the solution increases in viscosity from ambient temperature to body temperature; and diffuse reflective particles having an average particle size of at least about 1 micron.

Abstract: A polymer compound according to the invention comprises an acrylic acid copolymer composed of acrylic acid derivatives and/or methacrylic acid derivatives, containing: a) at least one acrylic acid derivative and/or methacrylic acid derivative substituted with a sulfonic acid group; b) at least one hydrophilically substituted acrylic acid derivative and/or methacrylic acid derivative; c) at least one lipophilically substituted acrylic acid derivative and/or methacrylic acid derivative; and d) at least one acrylic acid derivative and/or methacrylic acid derivative which acts as a crosslinking agent.

Abstract: An easily removable dental curable composition which prevents the fall or leakage of a temporary prosthetic appliance or a root canal filling material which is easily removed by bonding and adhering it to tooth, shows such high flowability that its operation is easy, has a long working time and excellent X-ray contrast properties and sealability and can be easily removed as required, and a filling kit. The dental curable composition comprises (A) a polymerizable monomer mixture containing a polymerizable monomer having an acid group in the molecule and (B) a polymerization initiator, wherein the component (A) contains (A?) a long-chain polymerizable monomer having a structure with a chain length of 17 or more atoms and/or the composition further comprises (D1) a soft resin material.

Abstract: [Problems] The invention provides a plastic lens for eyeglasses by using diethylene glycol bisallyl carbonate as a lens material and which is made to have a main absorption peak in a wavelength range of 565 nm to 605 nm by mixing a coloring agent in which a visible light-absorption spectroscopic spectrum contains an azaporphyrin compound and to be durable for use as eyeglasses and polarized eyeglasses owing to the good antiglare and visibility properties of the coloring agent. [Solving means] The eyeglass lens made of an allyl diglycol carbonate resin which has a main absorption peak of visible light spectroscopic transmittance in a wavelength range of 565 nm to 605 nm as shown in FIG. 1 is obtained by using diethylene glycol bisallyl carbonate as a lens material, mixing an organic coloring agent containing a tetraazaporphyrin compound, mixing a peroxyester type peroxide or a peroxyketal type peroxide with a 10 hour-half life temperature of 90 to 110° C.

Abstract: One aspect of the present invention relates to methods of sealing a wound or tissue plane or filling a void space, or securing meshes, films or other devices within the body. In certain embodiments, the wound is an ophthalmic, pleural or dural wound, or a hernia repair mesh. Remarkably, disclosed herein is the discovery that the use of certain crosslinkers in combination with polyalkyleneimines at specific concentrations can result in hydrogels with tunable degradation properties.

Abstract: The present invention relates to a thermochromic material for dental impression, capable of reversibly changing color depending on the temperature at which said material is found, a method for its preparation and the use thereof. Said material includes a bicomponent silicone composition in combination with at least a thermochromic pigment.

Abstract: A medical device has a structure made of a first biodegradable and/or bioabsorbable material and a second biodegradable and/or bioabsorbable material. The first biodegradable and/or bioabsorbable material has a degradation rate that is faster than a degradation rate of the second biodegradable and/or bioabsorbable material. And, the structure experiences a period of accelerated degradation upon exposure of the first biodegradable and/or bioabsorbable material.

Abstract: Compositions, kits and methods of preparing a biocompatible film for cosmetic or medical uses are disclosed. The compositions or kits contain polyvinyl acetal (PVA), siloxane and a solvent. The siloxane can have a hydrophilic group. Once the solvent content is reduced, for instance, by evaporation, the mixture of PVA and siloxane is solidified, forming a film. The compositions and kits, optionally, further include one or more of an antimicrobial agent, a pigment, an anti-inflammatory agent, an anesthetic agent or a hemostatic agent. Such a film can be used, for example, in the form of an antimicrobial sealant, a liquid bandage, body paints, scar camouflage, water-proof sun block, makeup sealer, or antimicrobial wipe or spray.

Abstract: An ophthalmic device is disclosed that is a polymerization product of a monomeric mixture comprising (a) a major amount of a non-silicone-containing hydrophilic monomer; (b) a hydrophobic monomer; and (c) a crosslinking agent, wherein the ophthalmic device has an equilibrium water content of at least about 70 weight percent and further wherein the ophthalmic device has an evaporative dehydration barrier layer on the surface thereof. A method for the mitigation of evaporative corneal dehydration employing the high water content ophthalmic device is also disclosed.

Abstract: New ampholyte biomaterial compounds containing ampholyte moieties are synthesized and integrated into polymeric assemblies to provide hydrophilic polymers exhibiting improved biocompatibility, haemocompatibility, hydrophilicity non-thrombogenicity, anti-bacterial ability, and mechanical strength, as well as suitability as a drug delivery platform.

Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.

Abstract: Polymeric compositions for enhanced wound or burn treatment characteristics and other medical, industrial, recreational and domestic applications can be formulated as biocompatible, elastomeric, polymers. Such compositions can be used as advanced wound or burn care dressings or for other medical and non-medical purposes. The compositions generally comprise a polymeric component including a polyurethane oligomer or polymer with one or more hydroxyl-containing acrylate or methacrylate terminal groups thereon, and an effective amount of a mercaptan (thiol) to regulate elastic and adhesive properties of the cured composition. During medical uses, the composition may be applied in a thin layer on the affected area and a generous portion of the adjacent healthy skin. The composition is then cured such as by exposure to an external energy source, for example a visible light or an ultraviolet light or infrared light or sunlight or a combination thereof, to form an elastomeric dressing.

Abstract: The present invention relates generally to production of thermoplastic materials which swell in water to produce hydrogels. These materials will hereafter be referred to as “thermoplastic hydrogels”. They are useful as contact lenses or for use in vision correction prosthetics or as cosmetic devices. In particular, the invention relates to thermoplastic hydrogels which show improved flow characteristics.

Abstract: Novel biodegradable polyesteramides derived from optionally functionalized diacids and optionally functionalized diamines or from compounds having both optionally functionalized acid and optionally functionalized amine moieties, their preparation, and absorbable surgical articles fabricated therefrom, such as monofilament and multifilament sutures, films, sheets, plates, clips, staples, pins, screws, stents, stent coatings, packaging materials, and other implantable surgical devices, and the like, are described herein.

Abstract: The present invention relates to aqueous polyurethane dispersions for sealing teats of animal mammary glands.

Abstract: The present disclosure relates to a nail coating system comprising a basecoat, a color layer, and a topcoat. The system of the present disclosure may be applied to natural and/or pre-existing artificial nail coatings. The present disclosure relates generally to compositions for natural and artificial nail coatings, and particularly, but not by way of limitation, to polymerizable compositions and color layers polymerized therefrom. The disclosure further relates to methods of making a polymerized color layer.

Abstract: The invention provides a method for preparing a hydrogel from a hydrophilic polymer having one or more functional groups which are capable of co-reacting in a condensation reaction which method comprises the steps of: (i) preparing a solution of the polymer; (ii) heating the solution to a temperature sufficient for the condensation reaction to take place for a period of time sufficient for the hydrogel to cross-link wherein where the hydrophilic polymer comprises a first and a second hydrophilic polymer, step (i) comprises a step of mixing the hydrophilic polymers to prepare a homogeneous intimate mixture of the polymers; and wherein the heating step (ii) is carried out at a pressure greater than atmospheric pressure. The method of the invention is advantageous because it is relatively low cost, it is a safer procedure with less health & safety concerns, it is carried out in a liquid state and is not limited by film thickness.

Abstract: A transparent polymeric nanocomposite hydrogel is provided, wherein the polymeric nanocomposite hydrogel is made from a water insoluble polymer, i.e. poly(2-hydroxyethyl methacrylate) (PHEMA) or/and crosslinked PHEMA and a water insoluble nanofiber, i.e., bacterial cellulose (BC). Disclosed is a synthetic route for polymeric nanocomposites hydrogels. The preferred polymeric nanocompositions are produced through free radical polymerization of HEMA monomer in the presence of bacterial cellulose with an assistance of ultrasound to enhance the mixing of bacterial cellulose, initiator, and the monomers. The polymeric nanocomposite hydrogel is then formed by immersion of the dry polymeric nanocomposite in water. Disclosed is a high transmittance polymer nanocomposite hydrogel with a preferred BC loading less than 0.1%, water content of about 40% in weight, good mechanical integrity and strength.

Abstract: Antimicrobial parylene coatings and methods for their vapor-phase deposition.

Abstract: Since a medium having light propagation properties and sound propagation properties similar to those of human tissues is provided, reflection of light and an acoustic wave at a surface of a test portion is prevented, and accuracy control of a photoacoustic wave diagnostic apparatus is realized. A photoacoustic matching material is provided which includes a polyol, an inorganic oxide, and a pigment, the latter two being dispersable in the polyol, and in this photoacoustic matching material, a dispersed amount of the inorganic oxide to the polyol is in a range of 0.10 to 0.25 percent by weight, and a dispersed amount of the pigment to the polyol is in a range of 0.0001 to 0.0005 percent by weight.

Abstract: The present invention includes a novel shapeable material or resin, specifically for dental use. It is an improvement over conventional dental resins because it is strong, safe, does not encourage the propagation of bacteria and contains no bisphenol A (BPA). Also, it is the preferred resiliency for use in the oral cavity.

Abstract: The present invention pertains to polyisobutylene urethane, urea and urethane/urea copolymers, to methods of making such copolymers and to medical devices that contain such polymers. According to certain aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment, an additional polymeric segment that is not a polyisobutylene segment, and a segment comprising a residue of a diisocyanate. According to other aspects of the invention, polyisobutylene urethane, urea and urethane/urea copolymers are provided, which comprise a polyisobutylene segment and end groups that comprise alkyl-, alkenyl- or alkynyl-chain-containing end groups.

Abstract: Generally, hydrogels are prepared by forming a liquid reaction mixture that contains a) monomer(s) and/or polymer(s) at least portion(s) of which are sensitive to environmental changes (e.g., changes in pH or temperature), b) a crosslinker and c) a polymerization initiator. If desired, a porosigen may be incorporated into the liquid reaction mixture to create pores. After the hydrogel is formed, the porosigen is removed to create pores in the hydrogel. These hydrogels may be prepared in many forms including pellets, filaments, and particles. Biomedical uses of these hydrogels include applications wherein the hydrogel is implanted in the body of a patient and an environmental condition at the implantation site causes the hydrogel to expand in situ.

Abstract: A method is provided for shaping breast tissue via a liquid adhesive that may be applied to an article of clothing and/or a portion of a breast of a user. The liquid adhesive can be applied to a breast or clothing of a user. The breast may then be positioned within the clothing to maintain the desired appearance. A liquid adhesive is further provided that includes a mixture of a polymer and a solvent, where the mixture has a pH ranging from about 6 to about 8 and where the solvent comprises denatured alcohol and water and where the polymer is selected from the group consisting of: a methacrylate copolymer; a polyquaternium cationic polymer, a poly(acrylic acid) polymer; an acrylate copolymer; and combinations of two or more of the foregoing.

Abstract: A composition comprising thermoset shape memory polymer and a composition for molecular scale healing is disclosed; the composition has the ability to resolve structural defects by a close-then-heal mechanism. In use the shape memory polymer serves to bring opposing surfaces in a structural defect into proximity, whereafter heating the molecular scale healing composition to a level at or above its melting point allows for molecular scale healing. The composition has the ability to close macroscopic defects, and to do so repeatedly even if another wound occurs in a previously healed area.

Abstract: The disclosed is a biodegradable copolymer, an amphiphilic diblock copolymer, composed of a hydrophilic segment and a hydrophobic segment. The hydrophilic segment is an endcapped PEG or derivatives thereof. The hydrophilic segment is a random polymer polymerized of lactone or cyclic C3-C6 molecule and lactic acid/glycolic acid. There is no coupling agent between the hydrophilic and hydrophobic segments, and the biodegradable copolymer is formed by one-pot ring-opening polymerization. The biodegradable copolymer can be dissolved in water to form a thermosensitive material having a phase transfer temperature of 25 to 50° C., thereby being applied to biological activity factor delivery, tissue engineering, cell culture and biological glue.

Abstract: A system for flavoring silicone products, such as baby bottle nipples and baby pacifiers, and a system for forming the flavored silicone products. Flavors, in the form of esters, are bond to Silicon (IV) Oxide, the resulting flavored intermediate is mixed into silicone, and the mixture is formed into a flavored product.

Abstract: A subject-matter of the invention is an impression material with at least one compound with at least two alkenyl groups as component (a), at least one compound with at least one chelating group as component (b), at least one organohydropolysiloxane as component (c), at least one hydrosilylation catalyst as component (d) and at least one compound with a chelatable metal atom as component (e), the chelating group of the component (b) exhibiting no reactive groups which can react with the component (c) and/or the component (d). The invention achieves a long storage stability.

Abstract: A durable skin marking composition that remains legible and visible on the skin after being treated with an aqueous, alcohol-based solution. The skin marking composition of the present invention includes a cyanoacrylate base and a colorant. The cyanoacrylate base can be n-butyl cyanoacrylate, 2-ethyl-cyanoacrylate, 2-octyl-cyanoacrylate, or a combination of the foregoing. The colorant can be a dye, pigment, contrast agent, colored particle, fluorescent particle, radio-opaque particle, or a combination of the foregoing. The composition can further comprise one or more of viscosity modifiers/thickening agents, stabilizers, plasticizers, formaldehyde scavengers, polymerization accelerators, perfumes, adhesion promoters, and anti-bacterial, anti-fungal, anti-viral, or anti-microbial agents.

Abstract: Method for dyeing a substrate prepared by curing a polymerizable composition having one monomer containing one episulfide group, the method including: providing a dye solution including a dye and a carrier in a solvent, the carrier being chosen from the compounds represented by the following formulae (1) and (2): wherein R1, R2, R3 and R4 are each selected from the group consisting of alkyl having from 1 to 10 carbon atom, H, —CH2SH, —CH2SCH2CH2SH, wherein m denotes an integer from 1 to 3; and at least partially immersing the substrate in the dye solution for a time sufficient to allow the effective tinting of the substrate.

Abstract: The present disclosure provides copolymers including a first monomer including at least one phospholipid possessing at least one hydroxyl group and a second monomer including a cyclic monomer. Compositions, medical devices, and coatings including such copolymers are also provided.

Abstract: The invention features a dental composition containing a polycyclic aromatic compound, such as 2-ethyl 9,10-dimethoxy anthracene (EDMOA), in an amount that provides the composition with fluorescence mimicking that of natural teeth.

Abstract: The invention provide a new class of silicone-containing prepolymers containing dangling polysiloxane-containing polymer chains. This class of silicone-containing prepolymer is capable of being actinically crosslinked to form a silicone hydrogel material with a relatively high oxygen permeability, a reduced elastic modulus, and a relatively high ion permeability. The present invention is also related to silicone hydrogel contact lenses made from this class of silicone-containing prepolymers and to methods for making the silicone hydrogel contact lenses.