Contact Lens Making Composition Patents (Class 523/106)
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Patent number: 8927618Abstract: The present invention provides a dye composition for an ophthalmic lens, which is a dye composition used for dyeing an ophthalmic lens with an ink-jet coating equipment, characterized by the composition including: (A) a dye having at least one group having a carbon-carbon double bond selected from an ?,?-unsaturated carbonyl group, a styryl group, a vinylbenzyl group and an allyl group per molecule; (B) a radical polymerization initiator; and (C) a solvent capable of dissolving at least a part of the component (A) and the component (B), and/or (D) a monomer having at least one radical polymerizable group per molecule.Type: GrantFiled: November 18, 2010Date of Patent: January 6, 2015Assignee: Menicon Co., Ltd.Inventors: Yuji Goto, Ichiro Ando, Ryo Matsushita
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Patent number: 8921449Abstract: In one aspect, the invention relates to hydrolysis-resistant silicone compounds. In particular, disclosed are sterically hindered hydrolysis-resistant silicone compounds and improved purity hydrolysis-resistant silicone compounds. Also disclosed are processes for making hydrolysis-resistant silicone compounds; the products of the disclosed processes; compositions and polymers comprising the disclosed compounds and products of the disclosed processes; and ophthalmic lenses, for example contact lenses, intraocular lenses, artificial cornea, and spectacle lenses, comprising the disclosed compositions, disclosed polymers, disclosed compounds, and products of the disclosed processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.Type: GrantFiled: January 21, 2013Date of Patent: December 30, 2014Assignees: Johnson & Johnson Vision Care Inc., Toray Industries, Inc.Inventors: Kazuhiko Fujisawa, Masataka Nakamura, Mitsuru Yokota, Douglas G. Vanderlaan
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Patent number: 8916622Abstract: A heat-curable composition comprises—from 25 to 65% by weight of a mixture of epoxy-functional monomers, said mixture consisting of at least one polyfunctional epoxy monomer selected from monomers comprising from 4 to 8 glycidyl groups and/or cycloaliphatic epoxy groups, and at least one bi- or tri-functional epoxy monomer selected from monomers comprising two or three glycidyl groups and/or cycloaliphatic epoxy groups, —from 25 to 70% by weight of at least one organic solvent selected from glycol monoethers, —from 2.5 to 5% by weight, relative to the total weight of epoxyfunctional monomers (a) and (b), of at least one blocked strong acid catalyst, said heat-curable composition not containing any non-epoxyfunctional monomers, in particular not containing any acrylic, methacrylic or silane monomers.Type: GrantFiled: December 17, 2009Date of Patent: December 23, 2014Assignee: Essilor Internatonal (Compagnie Générale d'Optique)Inventor: Robert Valeri
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Patent number: 8901190Abstract: A method for modifying the refractive index of an optical, hydrogel polymeric material. The method comprises irradiating predetermined regions of an optical, polymeric material with a laser to form refractive structures. To facilitate the formation of the refractive structures the optical, hydrogel polymeric material comprises a photosensitizer. The presence of the photosensitizer permits one to set a scan rate to a value that is at least fifty times greater than a scan rate without the photosensitizer in the material, yet provides similar refractive structures in terms of the observed change in refractive index. Alternatively, the photosensitizer in the polymeric material permits one to set an average laser power to a value that is at least two times less than an average laser power without the photosensitizer in the material, yet provide similar refractive structures.Type: GrantFiled: September 27, 2012Date of Patent: December 2, 2014Assignees: University of Rochester, Rochester Institute of TechnologyInventors: Thomas Smith, Wayne H. Knox, Li Ding, Dharmendra Jani, Jeffrey G. Linhardt
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Publication number: 20140333893Abstract: Provided are a low hydrous soft ophthalmic lens that can remarkably reduce or avoid a phenomenon in which a lens sticks to a cornea when worn and can reduce a decrease in the performance of a coating layer when rubbing the low hydrous soft ophthalmic lens for cleaning and a method for manufacturing the same. The low hydrous soft ophthalmic lens has a layer formed of a hydrophilic polymer on at least part of the surface of a base material containing a polysiloxane compound, and at least part of the inside of the layer is cross-linked.Type: ApplicationFiled: August 15, 2012Publication date: November 13, 2014Applicant: Toray Industries, Inc.Inventors: Rumiko Kitagawa, Masataka Nakamura, Satoru Ogasahara
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Publication number: 20140336303Abstract: Described herein are devices, compositions, and methods for improving color discernment.Type: ApplicationFiled: July 22, 2014Publication date: November 13, 2014Inventors: Brett T. Harding, Sheng Li, Amane Mochizuki
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Patent number: 8883874Abstract: The present invention relates to compositions comprising a polymeric substrate comprising at least one volume excluding polymer. In one embodiment, the present invention provides polymeric articles that are capable of acting as osmotic drivers. The articles are capable of maintaining a desired water balance by moving water in or out of a substrate to maintain cation concentration equilibrium between the substrate and its environment.Type: GrantFiled: June 27, 2013Date of Patent: November 11, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Brian J. Tighe, Muriel Nasso, Beverley Benning, Frank F. Molock, Jr.
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Patent number: 8877829Abstract: The present invention relates to polymeric compositions useful in the manufacture of biocompatible medical devices. More particularly, the present invention relates to certain cationic monomers capable of polymerization to form polymeric compositions having desirable physical characteristics useful in the manufacture of ophthalmic devices. Such properties include the ability to extract the polymerized medical devices with water. This avoids the use of organic solvents as is typical in the art. The polymeric compositions comprise polymerized cationic hydrophilic siloxanyl monomers prepared by the process disclosed herein.Type: GrantFiled: September 24, 2010Date of Patent: November 4, 2014Assignee: Bausch & Lomb IncorporatedInventors: Derek A. Schorzman, Joseph C. Salamone, Daniel M. Ammon, Jr.
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Patent number: 8871016Abstract: The present invention provides cellulose hydrogels having one or more of the following properties: high water content, high transparency, high permeability, high biocompatibility, high tensile strength and an optimal thickness. The present invention further provides a process for preparing a cellulose hydrogel comprising: (i) contacting cellulose with a solvent to activate the cellulose; (ii) optionally removing the solvent from the activated cellulose; (iii) substantially dissolving the activated cellulose to form a solution; (iv) allowing the solution to gel; and optionally (v) drying the gel and rehydrating the gel. The cellulose hydrogel can have many uses, including uses as contact lenses.Type: GrantFiled: August 3, 2011Date of Patent: October 28, 2014Assignee: The Johns Hopkins UniversityInventors: Morgana M. Trexler, Jenna L. Graham, Jennifer L. Breidenich, Jeffrey P. Maranchi, Julia B. Patrone, Marcia W. Patchan, Jennifer H. Elisseeff, Xiomara Calderon-Colon
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Patent number: 8865929Abstract: A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound.Type: GrantFiled: July 17, 2012Date of Patent: October 21, 2014Assignee: CooperVision International Holding Company, LPInventors: Yuan Xu, Charlie Chen, Charles A. Francis, Shane Mao, Hong Xue, Xining Zhang
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Publication number: 20140309328Abstract: The present invention relates to polyurethane polymer compositions prepared by reacting a mixture comprising: a) at least one poly(ethylene glycol), b) at least one polyoxyalkylene diol (typically PPG or a copolymer of ethylene oxide and propylene oxide), c) at least one di- or poly-isocyanate, d) at least one polyol or macropolyol having a functionality greater than 2, or a mixture of such polyols or macropolyols having a functionality greater than 2, e) optionally an additional compound comprising at least one hydroxyl group and at least one primary or secondary amine group. The present invention also relates to an article comprising such a polymer, in particular a medical device such as a contact lens. A process for preparing a polyurethane hydrogel is also provided.Type: ApplicationFiled: April 19, 2012Publication date: October 16, 2014Applicant: Ocutec LimitedInventors: Rashid Abdul, Neil Bonnette Graham, Roderick Bowers, Wade Tipton, John Fraser
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Patent number: 8835526Abstract: The present invention provides optic portions, intraocular lenses, and polymers for use in manufacturing optic portions and intraocular lenses. The optic portions include a polymer that comprises (a) one or more alkoxyalkyl methacrylate monomers and/or one or more alkoxyalkyl acrylate monomers that are incorporated in the polymer; (b) one or more hydroxyalkyl methacrylate monomers and/or one or more hydroxyalkyl acrylate monomers that are incorporated in the polymer; and (c) optionally, one or more crosslinking agents that are incorporated in the polymer.Type: GrantFiled: November 19, 2012Date of Patent: September 16, 2014Assignee: Benz Research and Development CorporationInventors: Patrick H. Benz, Jose A. Ors
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Patent number: 8820925Abstract: Contact lenses, such as hydrogel contact lenses, are described. The present contact lenses include a lens body that is the reaction product of a polymerizable composition. The polymerizable composition includes one or more monomers and a crosslinker that crosslinks the one or more monomers during polymerization. The polymerization of the one or more monomers occurs in the presence of a hydrophilic polymer that is present in the polymerizable composition, which comprises a polymer of 2-methacryloyloxyethyl phosphorylcholine. The present lenses are capable of releasing the hydrophilic polymer from the contact lens for prolonged periods of time and also have a reduced surface friction compared to similar lenses without the hydrophilic polymer. The present invention also relates to packaging systems for use with such lenses and methods of producing such lenses.Type: GrantFiled: July 28, 2011Date of Patent: September 2, 2014Assignee: CooperVision International Holding Company, LPInventor: Yuwen Liu
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Patent number: 8807745Abstract: A substantially fully copolymerized UV blocking hydrogel lens demonstrating sufficient blocking of UV light to meet at least FDA Class II specifications for UV blocking formed from a reaction mixture comprising at least NVP and one other comonomer and a free-radical polymerizable, substituted or unsubstituted, Bis O-hydroxy benzophenone is provided herein.Type: GrantFiled: May 25, 2012Date of Patent: August 19, 2014Assignee: Bausch & Lomb IncorporatedInventors: Ivan Nunez, Jennifer Hunt
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Patent number: 8808866Abstract: An elastomeric article, such as a glove or a condom, is coated with a compound containing silicone, collagen and allantoin.Type: GrantFiled: February 5, 2013Date of Patent: August 19, 2014Assignees: Precision Components, Inc., Xela CorporationInventors: Anil Segat, Andreas Brown
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Patent number: 8759414Abstract: Described is the use of polymers with a high refractive index for ophthalmic products and a process for the production thereof.Type: GrantFiled: December 1, 2006Date of Patent: June 24, 2014Assignee: Coronis GmbHInventors: Wolfgang Müller-Lierheim, Joachim Storsberg, André Laschewsky, Eckhard Görnitz, Elsbeth Winter
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Patent number: 8741981Abstract: The invention provides silicone hydrogel contact lenses that exhibit reduced back surface debris and reduced incidence of superior epithelial arcurate lesions.Type: GrantFiled: February 7, 2013Date of Patent: June 3, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Robert B. Steffen, David C. Turner, Douglas G. Vanderlaan
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Patent number: 8729149Abstract: Embodiments of silicone hydrogels, ophthalmic lenses made therefrom, and methods of making the same are described. Fully hydrated silicone hydrogels have relatively high water content and oxygen permeability, along with relatively low modulus of elasticity. Embodiments of the silicone hydrogels in substantially dehydrated condition are adapted to lathe cutting at or above room temperature. Variations of the silicone hydrogels include silicon-containing monomers in an amount of 7.5% or greater by weight, a hydrophilic substituted N-vinyl acetamide monomer, and a hydrophilic non-acetamide monomer in an amount resulting in a hydrophilic substituted N-vinyl acetamide monomer to hydrophilic non-acetamide monomer weight to weight ratio of greater than 2.1 to 1.Type: GrantFiled: April 22, 2013Date of Patent: May 20, 2014Inventors: Timothy Higgs, Tristan Tapper, Richard Young
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Patent number: 8703875Abstract: The invention relates to novel crosslinkable copolymers which are obtainable by (a) copolymerizing at least two different hydrophilic monomers selected from the group consisting of N,N-dimethyl acrylamide (DMA), 2-hydroxyethyl acrylate (HEA), glycidyl methacrylate (GMA), N-vinylpyrrolidone (NVP), acrylic acid (AA) and a C1-C4-alkoxy polyethylene glycol(meth)acrylate having a weight average molecular weight of from 200 to 1500, and at least one crosslinker comprising two or more ethylenically unsaturated double bonds in the presence of a chain transfer agent having a functional group; and (b) reacting one or more functional groups of the resulting copolymer with an organic compound having an ethylenically unsaturated group.Type: GrantFiled: February 27, 2013Date of Patent: April 22, 2014Assignee: Novartis AGInventors: Frank Chang, Norberto Arturo Medina
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Patent number: 8697770Abstract: A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.Type: GrantFiled: April 8, 2011Date of Patent: April 15, 2014Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Donnie J. Duis, Yongcheng Li, Leilani K. Sonoda, Holly L. Grammer
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Publication number: 20140096484Abstract: The present invention relates to improved contact lens products which not only have initial insertion comfort but also are comfortable to wear for more than about 6 hours. The invention is achieved by packaging and storing a hydrogel lens with two or more leachable polymeric lubricants incorporated therein in a relatively viscous packaging solution including a relatively low molecular weight polyethylene glycol (PEG) and a viscosity-enhancing hydrophilic polymer. The present invention also provides methods for making contact lens products of the invention.Type: ApplicationFiled: December 11, 2013Publication date: April 10, 2014Applicant: Novartis AGInventors: John Dallas Pruitt, Lynn Cook Winterton
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Patent number: 8686099Abstract: There is provided a mono-(meth)acrylate functionalized hydrophilic silicone monomers containing a polyether with branched linking group, useful in making water absorbing silicone-hydrogel films for contact lens applications. This invention also provides homo-polymers and copolymers made from the mono-(meth)acrylate functionalized hydrophilic silicone monomers described herein. Also provided is a process for producing the monomers and polymers described herein and contact lenses produced from the same.Type: GrantFiled: October 5, 2009Date of Patent: April 1, 2014Assignee: Momentive Performance Materials Inc.Inventors: Kendall Louis Guyer, Kenrick Martin Lewis, Sentihilkumar Umapathy, Anubhav Saxena, Yi-Feng Wang
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Patent number: 8680172Abstract: Some embodiments provide a copolymer comprising: an acrylate recurring unit and an optionally substituted vinylaryl recurring unit, wherein a portion of at least one of the recurring units comprises a vinyldialkylsiloxy pendant group. The copolymers may be useful as soft acrylic haptics for intraocular lenses. Some embodiments further relate to intraocular lenses having a hydrophobic soft acrylic optic and a silicone haptic, such as a dual optic accommodative lens a having hydrophobic soft acrylic anterior and posterior optic bodies and a silicone haptic. Related copolymeric composite materials as well as additional embodiments of intraocular lenses, are also described herein.Type: GrantFiled: April 23, 2013Date of Patent: March 25, 2014Assignee: Visiogen, Inc.Inventor: Xiugao Liao
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Publication number: 20140058008Abstract: A method of making an ocular lens device (and resulting lens device) from a polyolefin copolymer material having a crosslinking component, wherein the material is processed to remove unwanted reaction byproducts that can contribute to reduced transparency of the polyolefin copolymer material in the ocular environment of the eye.Type: ApplicationFiled: October 2, 2013Publication date: February 27, 2014Applicant: Innolene LLCInventors: Leonard Pinchuk, Yonghua Zhou, Yasushi Pedro Kato, Yongmoon Kwon
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Patent number: 8658747Abstract: Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group, the first siloxane monomer having a number average molecular weight of from 400 daltons to 700 daltons; and a second siloxane monomer having a number average molecular weight greater than 7,000 daltons; wherein a total amount of siloxane monomers present in the polymerizable composition is from 30 unit parts to 50 unit parts; the lenses also include units derived from at least one hydrophilic amide monomer having one N-vinyl group that is present in the polymerizable composition in an amount from 30 to 60 unit parts.Type: GrantFiled: May 31, 2013Date of Patent: February 25, 2014Assignee: CooperVision International Holding Company, LPInventors: Yuwen Liu, Charlie Chen, Charles A. Francis, Junhao Ge, Yuan Xu, Li Yao, Arthur Back, Ying Zheng
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Patent number: 8658748Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. The average energy loss of the silicone hydrogel contact lenses is from about 30% to about 45% when the lenses are fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.Type: GrantFiled: May 31, 2013Date of Patent: February 25, 2014Assignee: CooperVision International Holding Company, LPInventors: Ronghua Liu, Xinfeng Shi, Yuwen Liu, Charlie Chen, Ye Hong, Charles A. Francis, Li Yao, Arthur Back, Ying Zheng
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Patent number: 8642677Abstract: Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.Type: GrantFiled: February 24, 2012Date of Patent: February 4, 2014Assignee: CooperVision International Holding Company, LPInventors: Guigui Wang, Yun Zhang, Yuwen Liu, Ye Hong, Charlie Chen, Peter Zhu
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Patent number: 8618187Abstract: There is described a composition for forming an contact lens, in particular for forming a silicone hydrogel contact lens, comprising at least one first vinylic monomer or macromer having one first ethylenically unsaturated group and at least one second vinylic monomer or macromer having one second ethylenically unsaturated group, wherein the first and second ethylenically unsaturated groups are different from each other and wherein the composition further comprises a crosslinker with at least two ethylenically unsaturated (polymerizable) groups with a selected kinetic copolymerization parameter r1 of less than 1.0 relative to one of the first and second ethylenically unsaturated (polymerizable) groups as defined above.Type: GrantFiled: March 29, 2012Date of Patent: December 31, 2013Assignee: Novartis AGInventors: Bernhard Seiferling, Thomas Schmidt, Jürgen Vogt
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Patent number: 8614261Abstract: Ophthalmically compatible contact lenses include lens bodies configured for placement on a cornea of an animal or human eye. The lens bodies are made of a hydrophilic silicon-containing polymeric material. The lens bodies have oxygen permeabilities, water content, surface wettabilities, flexibilities, and/or designs to be worn by a lens wearer even during sleep. The present lenses can be worn on a daily basis, including overnight, or can be worn for several days, such as about thirty days, without requiring removal or cleaning.Type: GrantFiled: March 26, 2012Date of Patent: December 24, 2013Assignee: CooperVision International Holding Company LPInventors: Junichi Iwata, Tsuneo Hoki, Seiichirou Ikawa, Arthur Back
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Patent number: 8609745Abstract: The invention provide a new lens curing method for making hydrogel contact lenses. The new lens curing method is based on actinically-induced step-growth polymerization. The invention also provides hydrogel contact lenses prepared from the method of the invention and fluid compositions for making hydrogel contact lenses based on the new lens curing method. In addition, the invention provide prepolymers capable of undergoing actinically-induced step-growth polymerization to form hydrogel contact lenses.Type: GrantFiled: December 12, 2012Date of Patent: December 17, 2013Assignee: Novartis AGInventors: Arturo Norberto Medina, Dawn Alison Smith, Robert Scott
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Publication number: 20130317132Abstract: The present invention relates to biomedical devices, and particularly contact lenses comprising a polymer having entangled therein at least one polymer comprising repeating units from N-(2-hydroxyalkyl)(meth)acrylamide.Type: ApplicationFiled: May 22, 2013Publication date: November 28, 2013Inventors: Charles W. Scales, Kevin P. McCabe, Brent Matthew Healy
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Patent number: 8585938Abstract: UV absorbing compounds that are effective in blocking UV and short-wavelength blue light are disclosed. The UV absorbing compounds are particularly suitable for use in intraocular lens materials.Type: GrantFiled: March 29, 2013Date of Patent: November 19, 2013Assignee: Novartis AGInventors: David L. Jinkerson, Walter R. Laredo
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Publication number: 20130274370Abstract: The present invention relates to a polyurethane polymer composition prepared by reacting a mixture comprising: a} at least one polyethylene glycol, and either b) at least one poly-isocyanate, having a functionality greater than 2 or c) at least one di-isocyanate and at least one polyol or at least one macropolyol having a functionality greater than 2, wherein the polyol or macropolyol is present at an amount of 0.1 to 9 wt % of the mixture. The invention also relates to a process for preparing a polyurethane xero-gel in the form of a moulded article, said process comprising the steps of: i.) preparing said mixture; ii. ) dispensing the reaction mixture formed in step i) into a mould; iii. ) allowing the reaction mixture to react and cure; iv. ) removing the moulded article from the mould; and v. ) hydrating the moulded article.Type: ApplicationFiled: October 24, 2011Publication date: October 17, 2013Inventors: Rashid Abdul, Neil Bonnette Graham
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Patent number: 8557892Abstract: Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing macromer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices.Type: GrantFiled: June 1, 2012Date of Patent: October 15, 2013Assignee: Novartis AGInventor: Walter R. Laredo
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Patent number: 8552085Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.Type: GrantFiled: July 2, 2012Date of Patent: October 8, 2013Assignee: CooperVision International Holding Company, LPInventors: Ye Hong, Charlie Chen, Nick Manesis
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Patent number: 8513324Abstract: The present invention relates to a composition comprising a hydrogel polymer having less than 100% haze, and distributed therein an oxygen enhancing effective amount of oxygen permeable particles having an oxygen permeability of at least about 100 barrer, average particle size less than about 5000 nm.Type: GrantFiled: January 9, 2013Date of Patent: August 20, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Charles W. Scales, Gregory A. Hill, John B. Enns, Eric R. George
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Patent number: 8513325Abstract: Silicone hydrogel contact lenses are produced without using volatile organic solvents to extract materials from the polymerized contact lens bodies, and instead are washed with aqueous liquids. The silicone hydrogel contact lenses so produced have ophthalmically wettable lens surfaces. The hydrated silicone hydrogel contact lenses have diameters that are at least 24% larger than the diameters of the silicone hydrogel contact lenses prior to hydration or washing.Type: GrantFiled: February 24, 2012Date of Patent: August 20, 2013Assignee: CooperVision International Holding Company, LPInventors: Yuwen Liu, Charlie Chen, Ye Hong, Charles A. Francis, Li Yao, Arthur Back
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Patent number: 8507577Abstract: The present invention is a process for forming ophthalmic devices such as contact lenses, comprising the steps of curing a reactive mixture comprising at least one silicone-containing component, at least one hydrophilic component and at least one protonated diluent or protonatable diluent having a Hansen solubility parameter, ?p between about 2 and about 7 to form an ophthalmic device having an advancing contact angle of less than about 80°; contacting the ophthalmic device with an aqueous solution which is capable of changing the Hansen solubility parameter, ?p of the protonated or protonatable co-diluent to enhance water solubility and removing said diluent(s) with said aqueous solution.Type: GrantFiled: October 18, 2007Date of Patent: August 13, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Diana Zanini, Karen Altheim
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Patent number: 8501832Abstract: The present invention relates to compositions comprising a polymeric substrate comprising at least one volume excluding polymer. In one embodiment, the present invention provides polymeric articles that are capable of acting as osmotic drivers. The articles are capable of maintaining a desired water balance by moving water in or out of a substrate to maintain cation concentration equilibrium between the substrate and its environment.Type: GrantFiled: April 28, 2011Date of Patent: August 6, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Brian J. Tighe, Muriel Nasso, Beverley Benning, Frank F. Molock, Jr.
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Patent number: 8487058Abstract: Ophthalmically acceptably wettable silicone hydrogel contact lenses are described. The lenses are derived from a polymerizable composition including a first siloxane monomer. The lenses have ophthalmically acceptably wettable lens surfaces when fully hydrated. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.Type: GrantFiled: February 24, 2012Date of Patent: July 16, 2013Assignee: CooperVision International Holding Company, LPInventors: Yuwen Liu, Charlie Chen, Charles A. Francis, Junhao Ge, Yuan Xu, Li Yao, Arthur Back, Ying Zheng
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Patent number: 8481662Abstract: Silicone hydrogel contact lenses having ophthalmically acceptable levels of energy loss are described. The lenses are derived from a polymerizable composition including a first siloxane monomer represented by formula (1): wherein m of formula (1) represents one integer from 3 to 10, n of formula (1) represents one integer from 1 to 10, R1 of formula (1) is an alkyl group having from 1 to 4 carbon atoms, and each R2 of formula (1) is independently either a hydrogen atom or a methyl group; the lenses also include units derived from a second siloxane monomer which is a dual-end methacrylate end-capped polydimethylsiloxane having a number average molecular weight of at least 7,000 daltons. Batches of silicone hydrogel contact lenses and methods of making silicone hydrogel contact lenses are also described.Type: GrantFiled: February 24, 2012Date of Patent: July 9, 2013Assignee: CooperVision International Holding Company, LPInventors: Ronghua Liu, Xinfeng Shi, Yuwen Liu, Charlie Chen, Ye Hong, Charles A. Francis, Li Yao, Arthur Back, Ying Zheng
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Patent number: 8476336Abstract: The invention relates to an ophthalmologic composition including a dye of the general formula I in which R1=substituted or unsubstituted hydrocarbon radical, R2=substituted or unsubstituted hydrocarbon radical with at least one polymerizable double bond, R3?H or substituted or unsubstituted hydrocarbon radical, R4?H, electron-withdrawing substituent or substituted or unsubstituted hydrocarbon radical and X?O, S, NH or NR5, wherein R5 is a substituted and/or unsubstituted hydrocarbon radical. Moreover, the invention relates to another ophthalmologic composition and an ophthalmologic lens.Type: GrantFiled: December 17, 2009Date of Patent: July 2, 2013Assignee: Acri.Tec GmbHInventor: Juergen Nachbaur
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Patent number: 8475691Abstract: Novel UV absorbing monomers are disclosed. The UV absorbers are particularly suitable for use in intraocular lens materials.Type: GrantFiled: August 14, 2012Date of Patent: July 2, 2013Assignee: Novartis AGInventor: Walter R. Laredo
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Patent number: 8476390Abstract: Polymer and monomer compositions based on a chromophore and improved light absorption. Lens materials can be fabricated. A composition comprising: a compound comprising a polymerizable vinyl group covalently linked to a benzene ring-based chromophore comprising: a substituent comprising a carbonyl group at the 1-position; a substituent comprising a hydroxy, ether, ester or a combination thereof at the 2-position; and a substituent comprising a (p-Nitrophenylazo) group at the 4 position of the benzene ring, including salts.Type: GrantFiled: April 25, 2008Date of Patent: July 2, 2013Inventors: Patrick H. Benz, Jose A. Ors
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Patent number: 8470906Abstract: The present invention relates to ionic silicone hydrogel polymers displaying improved thermal stability. More specifically, the present invention relates to a polymer formed from reactive components comprising at least one silicone component and at least one ionic component comprising at least one anionic group. The polymers of the present invention display good thermal stability and desirable protein uptake.Type: GrantFiled: September 25, 2009Date of Patent: June 25, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Osman Rathore, Zohra Fadli, Mark Lada, James D. Ford, Azaam Alli, Yongcheng Li
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Patent number: 8466209Abstract: Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing macromer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices.Type: GrantFiled: May 31, 2012Date of Patent: June 18, 2013Assignee: Novartis AGInventors: Ali E. Akinay, Walter R. Laredo
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Patent number: 8461226Abstract: A method of making a contact lens involves depositing on a portion of a molding surface of a contact lens mold a colorant composition comprising a pigment, a copolymer of 2-hydroxyethylmethacrylate and N-vinylpyrrolidinone, and a crosslinking monomer.Type: GrantFiled: July 13, 2010Date of Patent: June 11, 2013Assignee: Bausch & Lomb IncorporatedInventors: Richard Fanqing Meng, Shane Mao, Lawrence Chapoy
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Patent number: 8450387Abstract: This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.Type: GrantFiled: March 30, 2007Date of Patent: May 28, 2013Assignee: Johnson & Johnson Vision Care, Inc.Inventors: Kevin P. McCabe, Frank F. Molock, Gregory A. Hill, Azaam Alli, Robert B. Steffen, Douglas G. Vanderlaan, James D. Ford
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Patent number: 8449610Abstract: High refractive index copolymers with reduced glistenings are disclosed. The copolymers, which are particularly suitable for use as ophthalmic device materials, comprise a high molecular weight, reactive, linear polyethylene glycol component.Type: GrantFiled: June 20, 2011Date of Patent: May 28, 2013Assignee: Novartis AGInventors: Walter R. Laredo, Charles Freeman, Thomas A. Callaghan
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Publication number: 20130131214Abstract: The present invention relates to a composition comprising a hydrogel polymer having less than 100% haze, and distributed therein an oxygen enhancing effective amount of oxygen permeable particles having an oxygen permeability of at least about 100 barrer, average particle size less than about 5000 nm.Type: ApplicationFiled: January 9, 2013Publication date: May 23, 2013Applicant: JOHNSON & JOHNSON VISION CARE, INC.Inventor: JOHNSON & JOHNSON VISION CARE, INC.