Abstract: A method for producing a polymer, by continuously supplying and bringing at least a ring-opening polymerizable monomer and a compressive fluid into contact with each other, to thereby allow the ring-opening polymerizable monomer to carry out ring-opening polymerization to continuously generate a polymer.

Abstract: The Michael reaction is employed, for example, to condense methyl acrylate with diethyl malonate to prepare the corresponding tetra-ester. Subsequent reaction with primary amines followed by thermal condensation results in spiroimides. A similar series of reaction steps can be performed starting with malonamides.

Abstract: Copolymers, such as block copolymers, having at least one block that is a random copolymer of ?-caprolactone and ?-carboxy-?-caprolactone are described. Also described are methods of using such copolymers, such as, for example, in medical devices.

Abstract: The present invention relates to a method for making a polymer wherein during ring opening polymerisation is incorporated into the polymer chain at least one cyclic (alkyl) carbonate monomer having the formula (1) wherein Y is optional and represents the residue of a sulfhydryl reacted group, X represents a functional group reactive with a sulfhydryl group, L=—[CH2]n with n=0-10, or L=—[CH2]p-S—S—[CH2]q with p and q are 0-5 or L=-[PEG]- with PEG is a group that comprises a —[CH2CH2O]m-group with m=1-200, and R2 is hydrogen, methyl or ethyl. Optionally a cyclic (alkyl) acryloyl carbonate, or other additional monomer A may be used as comonomer. The polymer may be formed into a polymer article, such as a polymer film, such as a coating and modified and/or cross linked, to a polymer or polymer article obtainable, and to a biodevice, their use, and to the cyclic (alkyl)carbonates.

Abstract: The invention relates to polymers comprising NOS agonists and one or more monomers selected from the group consisting of lactide, glycolide and epsiloncaprolactone, wherein the NOS agonist is incorporated as repeating monomer units into the body or backbone of the polymer are disclosed. The NOS agonist may comprise one or more carboxylic acid groups and one or more alkylhydroxy groups. In another embodiment, the NOS agonist may comprise a carboxylic acid group and an alkylhydroxy group that can be joined to form a lactone containing cyclic ring. In another embodiment, the NOS agonist comprises HMG CoA reductase inhibitor or statin.

Abstract: Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.

Abstract: A synthetic construct suitable for implantation into a biological organism that includes at least one polymer scaffold; wherein the at least one polymer scaffold includes at least one layer of polymer fibers that have been deposited by electrospinning; wherein the orientation of the fibers in the at least one polymer scaffold relative to one another is generally parallel, random, or both; and wherein the at least one polymer scaffold has been adapted to function as at least one of a substantially two-dimensional implantable structure and a substantially three-dimensional implantable tubular structure.

Abstract: The present invention relates to a composition that can be used to manufacture an impermeable, sealing, tight envelope, to a process for manufacturing an impermeable envelope, and to a tank. The composition of the invention comprises in % by weight relative to the total weight of the composition: from 70 to 90% of a monomer (I); from 0.1 to 1% of an activator (II), in which R is chosen from the group comprising CnH2n+2, n being an integer chosen from 1 to 10; —OH; —OCn H2n+2, n being an integer chosen from 1 to 10; and —NHR? where R? is either CnH2n+2, n being an integer chosen from 1 to 10, or an amine functional group; from 2 to 6% of a catalyst (III), in which X is chosen from the group comprising MgBr, MgI, Li and Na; and from 10 to 20% of an additive (IV), with: This composition can be used, for example, to manufacture elements that are impermeable to fluids, for example impermeable envelopes, for example that can be used in the manufacture of type IV tanks or hydraulic accumulators.

Abstract: The present invention relates to a composition that can be used to manufacture an impermeable, sealing, tight envelope, to a process for manufacturing an impermeable envelope, and to a tank. The composition of the invention comprises in % by weight relative to the total weight of the composition: from 70 to 90% of a monomer (I); from 0.1 to 1% of an activator (II), in which R is chosen from the group comprising CnH2n+2, n being an integer chosen from 1 to 10; —OH; —OCnH2n+2, n being an integer chosen from 1 to 10; and —NHR? where R? is either CnH2n+2, n being an integer chosen from 1 to 10, or an amine functional group; from 2 to 6% of a catalyst (III), in which X is chosen from the group comprising MgBr, MgI, Li and Na; and from 10 to 20% of an additive (IV), with: This composition can be used, for example, to manufacture elements that are impermeable to fluids, for example impermeable envelopes, for example that can be used in the manufacture of type IV tanks or hydraulic accumulators.

Abstract: A polyimide including a structure shown as Formula II is provided, wherein X is halogen, A1 is selected from one of Formula 1 to Formula 18, and n is from 2 to 500,

Abstract: Thermoformed PLA stereocomplex parts are made using a PLA stereocomplex composition having a highest crystallization melting temperature from 200 to 215° C. The stereocomplex composition preferably has less than 5 J/g of lower melting (160 to 190° C.) crystallites. The stereocomplex can be pre-annealed in various ways to reduce thermoforming cycle times. The stereocomplex forms parts with low haze and good thermal resistance, at reasonable cycle times.

Abstract: A method of making a pure block copolymer includes forming a crude block copolymer; heating a solution of the crude block copolymer and alcohol; and cooling the solution to promote precipitation of a purified block copolymer, wherein an amount of impurities remaining in the purified block copolymer is from about 0 to about 5 wt % based on a total weight of the purified block copolymer; a ratio of a polydispersity index of the crude block copolymer to a polydispersity index of the purified block copolymer is from about 1.02 to about 1.25; a ratio of a molecular weight of the crude block copolymer to a molecular weight of the purified block copolymer is from about 0.75 to about 1.0; and a ratio of a number average molecular weight of the crude block copolymer to a number average molecular weight of the purified block copolymer is from about 0.65 to about 1.

Abstract: The invention provides non-naturally occurring microbial organisms containing caprolactone pathways having at least one exogenous nucleic acid encoding a butadiene pathway enzyme expressed in a sufficient amount to produce caprolactone. The invention additionally provides methods of using such microbial organisms to produce caprolactone by culturing a non-naturally occurring microbial organism containing caprolactone pathways as described herein under conditions and for a sufficient period of time to produce caprolactone.

Abstract: An object of the present invention is to provide a production process of an ?-hydroxy acid having a sufficient quality as a polymer raw material, which process does not produce a large amount of waste as a byproduct and is economical. The present invention provides a production process of an ?-hydroxy acid having a step of adding a basic metal to an ?-hydroxy acid ammonium salt to yield an ?-hydroxy acid metal salt and a step of desalting the ?-hydroxy acid metal salt to yield the ?-hydroxy acid.

Abstract: A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii) an end-graft polymer chain comprising a polylactone. Also disclosed are a method for treating bleeding from bone or bony structures using the composition, a method for filling a void or correct a defect in a bone using the composition, and a method for producing the biocompatible, polymeric composition of the present application.

Abstract: A method for producing a polymer, including: (i) continuously supplying and bringing at least a first monomer, which is ring-opening polymerizable, and a compressive fluid into contact with each other, to thereby allow the first monomer to carry out ring-opening polymerization to continuously generate an intermediate; and (ii) bringing the intermediate and a second monomer, which is identical to or different from the first monomer in kind, into contact with each other, to thereby allow the intermediate and the second monomer to carry out polymerization.

Abstract: Disclosed is a process for preparing a polyester or copolymer containing ester functionalities. The process can comprise: providing an optionally substituted lactone having a ring size of from 6 to 40 carbon atoms; and subjecting said lactone to metal mediated ring-opening polymerization using as catalyst a compound according to general formula (I): wherein M can be Al, Cr, Mn and Co; X and X? are independently a heteroatom; Y and Y? can be, independently, selected from O, N, S, P, C, Si, and B; Z can be selected from hydrogen, borohydrides, aluminum hydrides, carbyls, silyls, hydroxide, alkoxides, aryloxides, carboxylates, carbonates, carbamates, amidos, thiolates, phosphides, and halides; L1 and L2 can be independently an organic ligand linking X and Y together and linking X? and Y? together, respectively; and L3 is an optional organic ligand linking Y and Y? together.

Abstract: A method for producing a polymer, including: (i) bringing a compressive fluid and raw materials containing a ring-opening polymerizable monomer into contact with each other at a mixing ratio represented by the following formula, to thereby allow the ring-opening polymerizable monomer to carry out ring-opening polymerization: 1>{Mass of the raw materials/(Mass of the raw materials+Mass of the compressive fluid)}?0.5.

Abstract: Poly(glycolide) polymers are disclosed. The polymers generally include a polymerized alkynyl-substituted glycolide having a polymer backbone with one or more alkynyl groups appended thereto. The alkynyl groups provide reactive sites for further functionalization of the polymer, for example by reaction with azide derivatives (e.g., azide-substituted organic compounds). Alkynyl and azide groups react via the “click” chemistry mechanism to form functional groups covalently bonded to the polymer via a triazole link. The polymers are biodegradable and can be used to deliver drugs or other therapeutic substances (e.g., large biomolecules such as single strand RNA) at targeted locations in a patient's body and/or at controlled release rates.

Abstract: This disclosure provides a business method and system for generating sugars and recycling a non-biomass component from a waste stream. In some embodiments, a waste stream comprising cellulose and a non-biomass component is saccharified to produce glucose, followed by recovery of the glucose and non-biomass component, which may be recycled to another site associated with production of a cellulose-containing product that contains the non-biomass component. In certain scenarios, the waste stream is generated at a first location, cellulose pretreatment (if desired) and hydrolysis are conducted at a second location, and the non-biomass component is recycled to the first location or a third location. The non-biomass component may include metals, metal oxides, salts, organic compounds, inorganic compounds, oligomers, or polymers, for example.

Abstract: The present invention pertains to copolymers having one or more polyisobutylene segments and one or more biodegradable polymer segments, to methods of making such copolymers, to medical articles that contain such copolymers, and to methods of making such medical articles. According to certain aspects of the invention, copolymers are provided, which comprise a plurality of polyisobutylene segments and a plurality of biodegradable polymer segments. According to certain aspects of the invention, copolymers are provided, which comprise urethane linkages, urea linkages, amide linkages, ester linkages, anhydride linkages, carbonate linkages, linkages commonly described as “click” chemistry linkages, and combinations of two or more types of such linkages.

Abstract: Solid-state shear pulverization of semi-crystalline polymers and copolymers thereof and related methods for enhanced crystallization kinetics and physical/mechanical properties.

Abstract: A method for producing a crystallized polyester comprises the crystallization step of applying a shear and/or a pressure to a polyester selected from an aliphatic polyester and a polyalkylene terephthalate at a temperature of (Tm?70° C.) to (Tm+20° C.), where Tm is a melting point of the polyester, thereby converting the polyester into a state having a crystallinity of 10% or more and fluidity.

Abstract: The invention relates to a polymer network with triple-shape-memory effect and an associated programming method. The invention also relates to a method for producing layer systems made of shape-memory materials comprising the polymer network. The polymer network includes A) a first crystalline switching segment made of a star polymer; and B) a second crystalline switching segment made of a linear polymer or a star polymer.

Abstract: The present invention relates to a process for producing high-molecular-weight copolyesters with use of a kneader.

Abstract: A poly(lactone) of formula (I) wherein b=0 or 1; the molar ratio of w:r:s:t=(0-30):(99.9-2):(0-98):(0-30), and w+s+t is at least 1; R1? R2, and R3 are each independently a hydrogen or C1-4 alkyl; R4, R5, R6, and R7 are each independently hydrogen, C1-4 alkyl, or F wherein F is a functional group that imparts a property to the poly(lactone) I, at least one and no more than two of R4? R5, R6, and R7 are F, and F is the same or different in each instance; Q? is a C1-30 hydrocarbyl group post-reacted with a crosslinking group and optionally crosslinked with one to five additional polymer backbones, wherein the additional polymer backbone comprises units of formula I; G? is a single bond to an additional polymer backbone or G? is a C1-30 hydrocarbyl group crosslinked with one to five additional polymer backbones.

Abstract: Methods of making a biodegradable polymeric stent made from poly(L-lactide) and a low concentration of L-lactide monomer is disclosed. The concentration of L-lactide is adjusted to provide a degradation behavior that is suitable for different treatment applications including coronary, peripheral, and nasal. Methods include making a poly(L-lactide) material for a stent with uniformly distributed L-lactide monomer through control of polymerization conditions during PLLA synthesis, control of post-processing conditions, or both.

Abstract: An anti-reflective coating is obtained from a composition of at least one silane compound, at least one metal compound and at least one organic compound having at least two functional groups which can form a coordination polymer.

Abstract: The present invention relates to a process for the preparation of a lactone or lactam homopolymer, comprising the stage consisting in reacting a lactone or lactam with a nonpolymeric initiator comprising at least one hydroxyl or thiol functional group in a nonchlorinated solvent in the presence of a sulfonic acid of formula R—SO3H. It also relates to the polymer composition thus obtained and to its uses, in particular as antistatic additive.

Abstract: Biomedical and tissue engineering devices, such as surgical sutures and microporous scaffolds, respectively, which undergo swelling and increase in dimensions when placed in aqueous environments such as living tissues, are produced by the melt-spinning or electrostatic spinning into strong monofilament and multifilament yarns or microfibrous fabrics, respectively. Such devices are formed from especially high molecular weight crystalline polyether-esters having a minimum inherent viscosity of 0.8 dL/g and heat of fusion of at least 5 J/g, wherein the polyether-esters are made by grafting to a polyester component a polyether glycol component having a minimum molecular weight of about 11 kDa with at least one cyclic monomer.

Abstract: A method for producing particles, including: bringing a compressive fluid into contact with a pressure plastic material, so as to plasticize the pressure plastic material; applying a shear force to the compressive fluid and the plasticized pressure plastic material, between which an interface exists, in the presence of a surfactant to granulate the pressure plastic material in the compressive fluid, so as to produce particles.

Abstract: A blood anticoagulant material is provided which has high expandability, reduced influence on living bodies, and can efficiently prevent blood coagulation. A multiblock copolymer having at least a structural unit represented by Formula (1), a structural unit represented by Formula (2), and a structural unit represented by Formula (3) is used: wherein, R1, R2, and R3 in Formulas (1) to (3) each independently represent a divalent organic group, and m and n each independently represent an integer of 2 to 5000.

Abstract: Described herein are polymers comprising a polyester and at least one polyhedral oligomeric silsesquioxane, wherein the polyester is capable of forming a stereocomplex with a polymer comprising a complimentary polyester and composites thereof.

Abstract: A method for producing polymer particles, including (A) polymerizing and granulating a ring-opening polymerizable monomer in a compressive fluid with a catalyst in the presence of a surfactant, or (B) polymerizing and granulating an addition polymerizable monomer in a compressive fluid in the presence of a silicone surfactant.

Abstract: Methods and systems for controlling the moisture content of biodegradable and bioresorbable polymer resin during extrusion above a lower limit that allows for plasticization of the polymer resin melt and below an upper limit to reduce or prevent molecular weight loss are disclosed. Methods are further disclosed involving plasticization of a polymer resin for feeding into an extruder with carbon dioxide and freon.

Abstract: The present invention relates to a method for making a polymer wherein during ring opening polymerisation is incorporated into the polymer chain at least one cyclic (alkyl) carbonate monomer having the formula (1) wherein Y is optional and represents the residue of a sulfhydryl reacted group, X represents a functional group reactive with a sulfhydryl group, L=—[CH2]n with n=0-10, or L=?[CH2]p-S—S—[CH2]q with p and q are 0-5 or L=-[PEG]- with PEG is a group that comprises a —[CH2CH2O]m-group with m=1-200, and R2 is hydrogen, methyl or ethyl. Optionally a cyclic (alkyl) acryloyl carbonate, or other additional monomer A may be used as comonomer. The polymer may be formed into a polymer article, such as a polymer film, such as a coating and modified and/or cross linked, to a polymer or polymer article obtainable, and to a biodevice, their use, and to the cyclic (alkyl)carbonates.

Abstract: A biaxially oriented laminate film including a core layer including a blend of crystalline polylactic acid polymer and a minority amount of polyolefin with a compatibilizing resin which is biaxially oriented such that a matte or opaque appearance is obtained. The laminate film may further have additional layers such as a heat sealable layer disposed on one side of the core layer including an amorphous polylactic acid resin and/or a polylactic acid resin-containing layer disposed on the side of the core layer opposite the heat sealable layer, a metal layer, or combinations thereof.

Abstract: Absorbable and non-absorbable cyanoacrylate tissue adhesive/sealant formulations include at least one multipurpose carboxylic, acid-bearing C-succinylated polymeric rheology modifier capable of increasing the viscosity of the liquid formulation, while controlling the anionic polymerization of the cyanoacrylate monomers and increasing the compliance of the cured solid adhesive.

Abstract: A biaxially oriented laminate film including a core layer including a blend of crystalline polylactic acid polymer and a minority amount of polyolefin with a compatibilizing resin which is biaxially oriented such that a matte or opaque appearance is obtained. The laminate film may further have additional layers such as a heat sealable layer disposed on one side of the core layer including an amorphous polylactic acid resin and/or a polylactic acid resin-containing layer disposed on the side of the core layer opposite the heat sealable layer, a metal layer, or combinations thereof.

Abstract: Process for bulk polymerization of lactide at a temperature between 160° C. and 195° C. in the presence of a zinc-based catalyst.

Abstract: Novel semi-crystalline, segmented copolymers of lactide and epsilon-caprolactone exhibiting long term absorption characteristics are disclosed. The novel polymer compositions are useful for long term absorbable meshes, surgical sutures, especially monofilament sutures, and other medical devices.

Abstract: Disclosed is a polymer obtainable by bulk polymerization of lactide or lactic acid or a lactic acid copolymer obtainable by copolymerization of lactide or lactic acid with glycolide, glycolic acid and/or hydroxyacids in open or closed (cyclic) form in the presence of at least two organic and/or organic/inorganic chain regulators or a functionalized nanoparticle (nanosilica, montmorillonite).

Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings including block-polymers comprising at least one poly(hydroxyacid) or poly(hydroxy-alkanoate) block, at least one block of a biologically compatible polymer and at least one type of linking moiety.

Abstract: Disclosed herein is a polymer useful in a method of forming a wellbore fluid additive. This polymer comprises a polyethylene backbone comprising pendant aminoalkylsulfonic acid amides which comprise a carbonyl directly attached to a backbone carbon, and an amide formed via the amine group from the aminoalkylsulfonic acid. Methods of preparing these polymers by addition of the aminoalkylsulfonic acid to a polymeric anhydride are disclosed. Methods related to oil extraction using the wellbore fluid with the additive are also disclosed.

Abstract: The present disclosure provides a bio-based polyester resin comprising a polyacidic furan, including the manufacture of such polyester resin, which resin may be used in manufacturing toner for imaging devices.

Abstract: A process for producing an aliphatic polyester, comprising: subjecting at least two serial stages of bulk-phase ring-opening polymerization and a solid-phase polymerization step, wherein a cyclic ester held in a dry air atmosphere is supplied to a first reactor to perform a first stage polymerization, thereby obtaining a partially polymerized molten product, and the resultant partially polymerized molten product is supplied to a second reactor held under a dry inert gas atmosphere to perform a second stage polymerization. As a result, the production efficiency can be improved, while maintaining excellent properties of the aliphatic polyester product.

Abstract: Continuous processing methods for making absorbable polymeric films with one or more of the following properties: high toughness, low modulus, high tensile strength, and thickness less than 10 mm, more preferably less than 1 mm, and more preferably less than 100 ?m, have been developed. In the preferred embodiment, the polymer is a polyhydroxyalkanoate, and in the most preferred embodiment, the polymer comprises 4-hydroxybutyrate. A particularly preferred embodiment is a film of poly-4-hydroxybutyrate or copolymer thereof, wherein the film has a tensile strength greater than 5.5 kgf/mm2, tensile modulus less than 181 kgf/mm2, and elongation at break from 10-500%, wherein the film is derived by a continuous process such as melt extrusion or solvent casting, followed by orientation to more than 25% of the film's original length in one or more directions. These can be used for a variety of purposes including fabrication of medical devices.

Abstract: To provide a method for producing a polymer, which contains: bringing a compressive fluid and a ring-opening polymerizable monomer into contact with each other, followed by adding a catalyst thereto, to thereby allow the ring-opening polymerizable monomer to carry out ring-opening polymerization.

Abstract: An object of the present invention is to provide: a thermoplastic elastomer composition, which is accompanied by less environmental burden, and which has flexibility, rubber elasticity, formability and recyclability; and a molded product obtained using the same. The present invention is directed to a thermoplastic elastomer composition comprising a thermoplastic resin (A) derived from a non-petroleum source, and at least one rubber (B) selected from a natural rubber, a diene polymer rubber, an olefin polymer rubber, an acrylic rubber and a silicone rubber, the thermoplastic elastomer composition being obtained by allowing the rubber (B) to be dynamically crosslinked with a crosslinking agent (C) in the presence of the thermoplastic resin (A). Preferred (A) is a polylactic acid, or a poly(3-hydroxybutyrate), and preferred (B) is a natural rubber.

Abstract: A method of improving the mechanical properties of polymers is described. The method involves heat treating the polymer at a temperature below the glass transition temperature in a wet or in a dry environment. Polymer articles capable of moisture uptake in humid environments, as well as polymer articles less susceptible to moisture uptake, have improved mechanical properties, particularly improved stress relaxation behavior and set properties, when treated in accord with the heat treatment method.