Derived From Grain, E.g., Prolamines, Etc. Patents (Class 530/372)
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Publication number: 20120052086Abstract: A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid ? antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid ? peptide into a wild type seed storage protein.Type: ApplicationFiled: November 7, 2011Publication date: March 1, 2012Applicant: Hokko Chemical Industry Co., Ltd.Inventors: Teruhiko Terakawa, Hisakazu Hasegawa, Yasushi Shimada, Atsushi Takahashi, Takeshi Kawarabayashi, Mikio Shoji
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Publication number: 20110319596Abstract: A hybrid vegetable protein is described, comprising a guest protein having the structure of prolamine and glutelin, and a host protein having the structure of globulin and albumin, obtained from vegetable grains, such as corn and soybean, respectively. Likewise, a method for obtaining said hybrid vegetable protein is described, which comprises the steps of extracting the guest and host proteins, carrying out an acidification thereof, and further applying a magnetic field to provoke their attachment, and finally adding an alkali to the attached proteins to obtain a hybrid vegetable protein at its isoelectric point. The protein thus produced has a value higher than 0.97 according to the PDCAAS rating.Type: ApplicationFiled: March 12, 2009Publication date: December 29, 2011Applicant: INDUSTRIAS NUTRIGRAINS, S.A. DE C.VInventor: Jose De La Torre-Montemayor
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Publication number: 20110305817Abstract: The present invention relates to a method for separating protein from food by using an iso-electric point precipitation, comprising: obtaining a protein extract by adjusting pH of a raw material food in a media; precipitating the protein by adjusting pH of the protein extract to an iso-electric point of the desired protein; and recovering the protein precipitated after separating a protein filtrate through centrifuging the precipitated protein; in which the method may further include a heat-precipitation of the protein by heating the protein extract or the protein filtrate to 60˜145° C. The protein obtained in high yield according to the above method can be used as a food additive or a food nutritional enhancer.Type: ApplicationFiled: June 1, 2011Publication date: December 15, 2011Applicant: CJ Cheiljedang CorporationInventors: Seong Jun Cho, Sang Hyun Seo, Sung Wook Han, Je Hoon Ryu, Seung Won Park
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Publication number: 20110302674Abstract: The invention provides methods, polynucleotides and polypeptides useful for producing or selecting plants with increased tolerance to at least one environmental stress selected from drought, cold, freezing, heat and salinity. The invention also provides constructs, cells, plant cells and plants comprising the polynucleotides of the invention. The invention also provides plants produced by the methods of the invention. The invention also provides groups of plants selected by the methods of the invention.Type: ApplicationFiled: December 1, 2009Publication date: December 8, 2011Applicant: Vialactia Biosciences (NZ) LimitedInventors: Sathish Puthigae, Jonathan Robert Phillips, Claudia Jeannette Smith-Espinoza, Catheríne Jane Bryant, Kieran Michael Elborough
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Publication number: 20110289619Abstract: The present invention provides rice brown planthopper resistance gene Bph14. It has a nucleotide sequence as shown in SEQ ID NO:1 and its cDNA sequence is shown in SEQ ID NO:2. The Bph14 gene in the present invention belongs to the CC-NBS-LRR gene family, its coded protein is related to plant disease resistance. Bph14 gene has the function of resisting brown planthopper. By introducing Bph14 gene into ordinary rice variety through genetic transformation and cross breeding, the brown planthopper resistance of rice can be increased, so that the harm caused by brown planthopper can be alleviated and the aim of increasing and stabilizing production can be achieved.Type: ApplicationFiled: December 30, 2009Publication date: November 24, 2011Applicant: WUHAN UNIVERSITYInventors: Guangcun He, Bo Du, Weilin Zhang, Lili Zhu, Rongzhi Chen
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Publication number: 20110262478Abstract: An immunogen-specific is adjuvant for a vaccine or inoculum is disclosed. The adjuvant is comprised of particulate recombinant protein body-like assemblies (RPBLAs) that contain a recombinant fusion protein that contains two portions peptide-linked together. A first portion is a protein body-inducing sequence (PBIS) and a second portion is a T-cell stimulating immunogenic polypeptide whose sequence is that of a pathogenic polypeptide sequence present in or induced by a vaccine or inoculum. The adjuvant, when used as an inoculum in a host animal without a prior priming vaccination or inoculation, does not induce production of antibodies or T cell activation to the pathogenic sequence.Type: ApplicationFiled: October 9, 2009Publication date: October 27, 2011Applicant: Era Biotech, S.A.Inventors: Edward Peter Rybicki, Ann Elizabeth Meyers, François Devesa, Pablo Marzábal Luna, Inga Isabel Hitzeroth, Peter Öhlschläger
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Publication number: 20110265222Abstract: Provided are isolated polynucleotides comprising a nucleic acid sequence at least 80% identical to SEQ ID NO:619, 617, 606, 615, 629, 1-36, 40, 41, 43-45, 49, 52-56, 58, 113-343, 351, 354-358, 605, 607-614, 616, 618, 620-628, 630-638, 642, 645, 650, 651, 670, or 671. Also provided are nucleic acid constructs comprising same, isolated polypeptides encoded thereby, transgenic cells and transgenic plants comprising same and methods of using same for increasing abiotic stress tolerance, yield, biomass, growth rate, vigor, oil content, fiber yield, fiber quality, and/or nitrogen use efficiency of a plant.Type: ApplicationFiled: December 28, 2009Publication date: October 27, 2011Applicant: Evogene Ltd.Inventors: Sharon Ayal, Ayal Emmanuel, Zur Granevitze, Alex Diber, Basia Judith Vinocur, Hagai Karchi, Yoav Herschkovitz
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Patent number: 8007592Abstract: The present invention relates to plant cells and plants, which are genetically modified, whereby the genetic modification leads to an increase in the activity of a starch-phosphorylating OK1 protein in comparison to the corresponding wild type plant cells or wild type plants that have not been genetically modified. In addition, the present invention concerns means and methods for the manufacture of such plant cells and plants. These types of plant cells and plants synthesise a modified starch. Therefore, the present invention also concerns the starches synthesised from the plant cells and plants according to the invention, methods for manufacturing these starches, and the manufacture of starch derivatives of these modified starches, as well as flours containing starches according to the invention. Furthermore, the present invention also relates to nucleic acids, coding starch-phosphorylating OK1 proteins, vectors, host cells, plant cells, and plants containing such nucleic acid molecules.Type: GrantFiled: May 5, 2010Date of Patent: August 30, 2011Assignee: Bayer Cropscience AGInventors: Claus Frohberg, Oliver Koetting, Gerhard Ritte, Martin Steup
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Publication number: 20110185452Abstract: The invention provides an isolated polynucleotide encoding a polypeptide with the sequence of SEQ ID NO: 1 or a variant thereof, wherein the variant is a polypeptide capable of modulating in a plant at least one of: i) biomass, ii) seed yield, and III) tolerance to at least one environmental stress selected from drought, cold, freezing, heat and salinity. The invention also provides, construct, vectors, host cells, plant cells and plants genetically modified to comprise the polynucleotide. The invention also provides methods for producing and selecting plants that are altered for at least one of: i) biomass, ii) seed yield, and iii) tolerance to at least one environmental stress selected from drought, cold, freezing, heat and salinity, making use of the polynucleotides of the invention.Type: ApplicationFiled: May 28, 2009Publication date: July 28, 2011Inventors: Sathish Puthigae, Catherine Jane Bryant, Shivendra Bajaj, Kerry Robert Templeton
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Patent number: 7982009Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: October 13, 2010Date of Patent: July 19, 2011Assignee: Pioneer Hi-Bred International, Inc.Inventors: Kanwarpal S Dhugga, Haiyin Wang, Dwight Tomes, Timothy G Helentjaris
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Publication number: 20110173715Abstract: This invention relates generally to nucleic acid sequences encoding proteins that are associated with abiotic stress responses and abiotic stress tolerance in plants. In particular, this invention relates to nucleic acid sequences encoding proteins that confer drought, heat, cold, and/or salt tolerance to plants.Type: ApplicationFiled: September 23, 2005Publication date: July 14, 2011Applicant: BASF PLANT SCIENCE GMBHInventors: Piotr Puzio, Agnes Chardonnens, Harry Wild, Gunnar Plesch, Bryan McKersie
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Publication number: 20110173723Abstract: The present invention provides methods for identifying nucleic acid and polypeptide sequences which may be associated with a commercially relevant trait in plants, specifically, so-identified nucleic acids and polypeptide sequences for yield genes EG82013 and EG81345. Sequences thus identified are useful in enhancing commercially desired traits in domesticated plants or wild ancestor plants, identifying related nucleic acid sequences, genotyping a plant, and marker assisted breeding. Sequences thus identified may also be used to generate heterologous DNA, transgenic plants, and transfected host cells.Type: ApplicationFiled: July 29, 2009Publication date: July 14, 2011Applicant: EVOLUTIONARY GENOMICS, INC.Inventor: Walter Messier
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Publication number: 20110138496Abstract: The present invention provides a polypeptide which binds to a cis-element in the vicinity of a gene related to an iron-acquisition mechanism. The polypeptide can increase expression of the gene related to the iron-acquiring mechanism. This makes it possible to obtin a plant improved in tolerance to iron deficiency.Type: ApplicationFiled: April 24, 2008Publication date: June 9, 2011Inventors: Naoko Nishizawa, Satoshi Mori, Takanori Kobayashi, Yuko Ogo
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Publication number: 20110131684Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing yield-related traits by modulating expression in a plant of a nucleic acid encoding an MSR (Methionine_Sulfoxide_Reductase). The present invention also concerns plants having modulated expression of a nucleic acid encoding a MSR, which plants have enhanced yield-related relative to corresponding wild type plants or other control plants. The invention also provides constructs useful in the methods of the invention. Furthermore, the present invention relates generally to the field of molecular biology and concerns a method for enhancing yield-related traits by modulating expression in a plant of a nucleic acid encoding an Enolase. The present invention also concerns plants having modulated expression of a nucleic acid encoding an Enolase, which plants have enhanced yield-related traits relative to corresponding wild type plants or other control plants.Type: ApplicationFiled: July 14, 2009Publication date: June 2, 2011Inventors: Ana Isabel Sanz Molinero, Yves Hatzfeld, Christophe Reuzeau
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Publication number: 20110030090Abstract: The invention provides isolated peptide-methionine sulfoxide reductase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering peptide-methionine sulfoxide reductase levels in plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.Type: ApplicationFiled: April 1, 2010Publication date: February 3, 2011Applicant: E. I. du Pont de Nemours and CompanyInventors: Saverio Carl Falco, Omolayo O. Famodu, Blake C. Meyers, Guo-Hua Miao, Joan T. Odell, J. Antoni Rafalski, Catherine J. Thorpe, Hajime Sakai, Zude Weng
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Publication number: 20110016579Abstract: The invention provides a method for creating a transgenic plant comprising a gene containing a DNA to encode a transporter protein which selectively absorbs mugineic acid-iron complex. The transgenic plant is useful as a plant capable of growing in alkaline soil containing no bivalent iron but containing, for example, trivalent iron.Type: ApplicationFiled: November 24, 2005Publication date: January 20, 2011Applicants: SUNTORY LIMITED, SUNTORY HOLDINGS LIMITEDInventors: Yoshiko Murata, Takashi Iwashita
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Publication number: 20100319086Abstract: The present invention provides LEC1 variants. The LEC1 variants comprise a LEC1 A domain, a LEC1 B domain and a LEC1 C domain, where the LEC1 B domain has at least one mutation and/or is chimeric with respect to the LEC1 A or C domain. The invention also includes methods of preparing such LEC 1 variants, and methods of using such LEC1 variants to modulate the level or activity of LEC1 variants in a plant cell. Modulation of LEC1 activity or levels can be used for different purposes such as increasing embryo oil concentration, oil content of a seed or altering oil phenotype in a plant.Type: ApplicationFiled: December 30, 2009Publication date: December 16, 2010Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: BO SHEN, MITCHELL C. TARCZYNSKI, CHANGJIANG LI, KIMBERLY F. GLASSMAN, ARAGULA GURURAJ RAO, WUAS SHAANALEYZ
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Patent number: 7851597Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: June 17, 2009Date of Patent: December 14, 2010Assignee: Pioneer Hi-Bred International, Inc.Inventors: Kanwarpal S Dhugga, Haiyin Wang, Dwight Tomes, Timothy G Helentjaris
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Patent number: 7838632Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: May 19, 2010Date of Patent: November 23, 2010Assignee: Pioneer Hi-Bred International, IncInventors: Kanwarpal S Dhugga, Haiyin Wang, Dwight Tomes, Timothy G Helentjaris
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Publication number: 20100287664Abstract: The present invention relates to Pi5-1 and Pi5-2 proteins which enhance resistance to Mag-naporthe oryzae, genes which encode the proteins, a recombinant vector comprising the genes, a plant transformed with the recombinant vector and seeds thereof, a method of increasing re-sistance to a plant pathogen by expressing the genes in a plant, antibodies against the proteins, and a composition comprising the genes which are useful for enhancing resistance to a plant pathogen.Type: ApplicationFiled: July 15, 2009Publication date: November 11, 2010Applicants: University-Industry Cooperation Group of Kyung Hee University, The Regents of The University of CaliforniaInventors: Jong Seong Jeon, Pamela Ronald, Sang Kyu Lee, Min Young Song, Young Su Seo, Hye Kyung Kim, Se Ho Ko, Jung Pil Suh, Gi Hwan Yi, Gyn Heung An, Tae Ryoung Hahn, Jae Hwan Roh, Peijian Cao
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Publication number: 20100267613Abstract: A partial hydrolysate of cereal protein wherein the hydrolysate has a degree of hydrolysis between 9 and 18%, products containing such a partial hydrolysate and a method for the primary prevention of allergic reactions to cereal protein in a young mammal using such a partial hydrolysate are disclosed.Type: ApplicationFiled: December 12, 2008Publication date: October 21, 2010Applicant: NESTEC S.A.Inventors: Rodolphe Fritsche, Geraldine Ortega, Raphael Schaller, Antoine Wermeille
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Publication number: 20100105872Abstract: A composition is disclosed comprising a partially hydrolysed cereal protein. The partially hydrolysed cereal protein is characterised in that 20% to 80% by weight has a molecular weight of 25 kDa or greater 8% by weight or less has a molecular weight of 1.4 kDa or lower and in that it has a nitrogen solubility index of 90% or greater at pH 1 to 10. The preferred cereal protein derives from wheat. Also disclosed is a process for producing the composition comprising providing a slurry having a degree of hydrolysis of 3 to 8, determining the pH, adjusting the pH of the slurry and separating the aqueous-soluble portion of the slurry. Compositions according to the invention find use as milk protein replacements and as components in nutritional supplements, sports drinks, or food products including beverages.Type: ApplicationFiled: March 7, 2008Publication date: April 29, 2010Applicant: CARGILL, INCORPORATEDInventors: Jos Willy Ghislain Corneel De Sadelleer, Daniele Marie-Antoinette Karleskind, Catharina Hillagonda McCrae, Elisa Margriet Maria Meheus
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Publication number: 20090312525Abstract: The invention relates to an isolated aquaporin having a bound ligand, wherein said ligand close the conformation of said aquaporin and inhibit and/or reduce water transport of said aquaporin, and/or a high resolution structure of an isolated aquaporin in a closed conformation characterised by the coordinates deposited at the Protein Data Bank ID:1Z98, a crystal of said isolated aquaporin as well as the coordinates defining said crystal and the use of said aquaporin, and the use of the high-resolution structure as defined by the coordinates deposited at PDB ID:1Z98, and a method to produce said aquaporin.Type: ApplicationFiled: September 8, 2006Publication date: December 17, 2009Inventors: Per Kjellbom, Kristina Hedfalk, Susanna Törnroth, Maria Karlsson, Urban Johansson, Richard Neutze
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Patent number: 7579443Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: November 25, 2008Date of Patent: August 25, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: Kanwarpal S Dhugga, Haiyin Wang, Dwight Tomes, Timothy G Helentjaris
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Publication number: 20090178157Abstract: Disclosed are proteins, and nucleic acids encoding such proteins, involved in or associated with cell proliferation, senesence, differentiation, development, and stress response in plants. Also disclosed are uses for such proteins.Type: ApplicationFiled: October 15, 2008Publication date: July 9, 2009Inventor: Bret Cooper
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Patent number: 7524933Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: September 24, 2007Date of Patent: April 28, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: Kanwarpal S Dhugga, Haiyin Wang, Dwight Tomes, Timothy G Helentjaris
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Publication number: 20090069542Abstract: The present invention is directed to a method for processing a plant-based protein source, the method comprising an acidic extracting solution comprising a reducing agent is useful for extracting and isolating proteins from plant-based protein sources.Type: ApplicationFiled: September 27, 2007Publication date: March 12, 2009Applicant: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKAInventors: Yiqi Yang, Weijie XU, Narenda Reddy
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Patent number: 7498413Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include novel amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from maize. Nucleic acid molecules comprising nucleotide sequences that encode the antipathogenic polypeptides of the embodiments are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant a DNA construct comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the embodiments. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the embodiments in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.Type: GrantFiled: January 4, 2007Date of Patent: March 3, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: Mathias L. Muller, Carl R. Simmons, Nasser Yalpani
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Publication number: 20090031445Abstract: Expression systems that effect production of a GTPase activating protein in plants are used to modify plants to enhance their ability to resist traumaType: ApplicationFiled: June 18, 2008Publication date: January 29, 2009Inventors: Hon-Ming Lam, Samuel Sai Ming Sun
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Publication number: 20080250532Abstract: The present invention relates generally to an expression regulatory element operable in plants which includes oil palm, and in particular to an expression regulatory element operable selectively in the endosperm tissue of the plants. Said expression regulatory element comprises a sequence of nucleotides which specifically modulates the expression of a second nucleic acid molecule operably coupled to said expression regulatory element.Type: ApplicationFiled: March 13, 2008Publication date: October 9, 2008Applicant: MALAYSIAN PALM OIL BOARDInventors: Siti Nor Akmar Abdullah, Suan Choo Cheah, Nurniwalis Abd. Wahab
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Publication number: 20080229439Abstract: Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties.Type: ApplicationFiled: October 31, 2007Publication date: September 18, 2008Inventors: Thomas J. La Rosa, Linda Lutfiyya, Yihua Zhou, David K. Kovalic, Andrey A. Boukharov, Ping Li, Wei Wu, Timothy W. Conner, Jingdong Liu
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Patent number: 7385037Abstract: Method for the preparation of gliadin- and glutenin-rich fractions from gluten in an aqueous medium and in the presence of an acid, wherein the gluten are dispersed continuously or not in water up to a dry substance varying between 5 and 30%, by which the pH of the dispersion is monitored between 4.4 and 4.8 and the gluten-water mixture is submitted to shearing actions, through which the dispersion, continuously or not, can be fractionated in gliadin- and glutenin-rich fractions, by which a single gliadin-rich fraction with a gliadin/glutenin ratio of at least 2.5 is obtained, and a single glutenin-rich fraction with a gliadin/glutenin ratio of less than 0.8 is obtained.Type: GrantFiled: July 30, 2002Date of Patent: June 10, 2008Assignee: Tate & Lyle EuropeInventor: Stefaan Roels
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Patent number: 7307149Abstract: The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase levels in plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants comprising said nucleic acids.Type: GrantFiled: October 12, 2004Date of Patent: December 11, 2007Assignee: Pioneer Hi-Bred International, Inc.Inventors: Kanwarpal S. Dhugga, Haiyin Wang, Dwight Tomes, Timothy G. Helentjaris
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Patent number: 7144569Abstract: A method of diagnosing coeliac disease, or susceptibility to coeliac disease, in an individual comprising: (a) contacting a sample from the host with an agent selected from (i) the epitope comprising sequence which is: SEQ ID NO: 1 or 2, or an equivalent sequence from a naturally occurring homologue of the gliadin represented by SEQ ID NO: 3, (ii) an epitope comprising sequence comprising: SEQ ID NO: 1, or an equivalent sequence from a naturally occurring homologue of the gliadin represented by SEQ ID NO: 3, which epitope is an isolated oligopeptide derived from a gliadin protein, (ii) an analogue of (i) or (ii) which is capable of being recognised by a T cell receptor that recognises (i) or (ii), which in the case of a peptide analogue is not more than 50 amino acids in length, or (iv) a product comprising two or more agents as defined in (i), (ii) or (iii), and (b) determining in vitro whether T cells in the sample recognises the agent; recognition by the T cells indicating that the individual has, or is suType: GrantFiled: October 2, 2000Date of Patent: December 5, 2006Assignee: ISIS Innovation LimitedInventors: Robert Paul Anderson, Adrian Vivian Sinton Hill, Derek Parry Jewell
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Patent number: 7091312Abstract: The invention relates to novel nucleic acid and protein sequences from the mung bean Vigna radiata. The nucleic acid sequence, isolated from a bruchid resistant mung bean line, encodes a thionin-like protein with insecticidal properties.Type: GrantFiled: April 8, 2003Date of Patent: August 15, 2006Assignee: Academia SinicaInventors: Ching-San Chen, Kuan-Chung Chen, Cheng-Chun Kuan, Ching-Yu Lin
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Patent number: 6936703Abstract: The present invention concerns a method for the separation and/or isolation of inhibitors of cellulolytic, xylanolytic and/or beta-glucanolytic enzymes, inhibitors obtainable by said method, and process for obtaining micro-organism, plant or plant material wherein the activity of the inhibitor according to the invention is increased or reduced and to the use of the inhibitor, using the cited micro-organism, plant or plant material and/or the use of endoxylanases selected or modified using these inhibitors in a variety of process and applications.Type: GrantFiled: June 21, 2001Date of Patent: August 30, 2005Assignee: K.U. Leuven Research and DevelopmentInventors: Jan Delcour, Winok Debyser, Kurt Gebruers, Hans Goesaert, Katleen Fierens, Johan Robben, Steven Van Campenhout
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Patent number: 6762285Abstract: Bs2 resistance proteins that confer resistance to the plant pathogen Xanthomonas campestris are disclosed. These proteins may be expressed in transgenic plants that are otherwise susceptible to infection by this bacterium in order to enhance resistance.Type: GrantFiled: May 24, 2001Date of Patent: July 13, 2004Assignee: The Regents of the University of CaliforniaInventors: Brian J. Staskawicz, Douglas Dehlbeck, Thomas H. Tai
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Patent number: 6733578Abstract: Plasticized prolamine compositions and methods of preparing same are provided. The compositions can be used for making chewing gum bases, especially as biodegradable chewing gum bases. The inventive plasticizers are selected from a group of N-acyl derivatives of amino acids. The compositions are also useful for making other edible products as well as eco-friendly packaging films, coatings, adhesives, and encapsulation vehicles for medicament delivery and the like.Type: GrantFiled: June 20, 2002Date of Patent: May 11, 2004Assignee: Wm. Wrigley Jr. CompanyInventors: Jingping Liu, Willy Weisheng Lee
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Patent number: 6660495Abstract: The present invention relates to a process for the controlled enzymatic cleavage of purified and depigmented active allergenic proteins from indoor and outdoor source materials, which process produces fragments of allergens that retain the natural T-lymphocyte stimulating epitopes, but are depleted of IgE-binding B-cell epitopes and complement-activating agents. The invention also relates to the new pharmaceutical products. These allergen fragments do not exhibit the disadvantages of conventional allergenic extracts for immunotherapy and can be safely used to induce a state of specific T-cell anergy and immunological tolerance in allergic human beings.Type: GrantFiled: December 4, 2001Date of Patent: December 9, 2003Assignee: C.B.F. Leti, S.A.Inventors: Lubertus Berrens, Maria Leticia Gonzales Romano, Maria Teresa Gallego Camara
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Patent number: 6632925Abstract: The present invention includes biodegradable plant protein composites.Type: GrantFiled: May 3, 2000Date of Patent: October 14, 2003Assignee: Iowa State University Research Foundation, Inc.Inventors: Jinwen Zhang, Perminus Mungara, Jay-Lin Jane
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Patent number: 6599725Abstract: The present invention is drawn to methods and compositions for suppressing cell death in plants. Specifically, novel proteins and genes are provided for use in plant transformation. The proteins and genes are useful for activating disease resistance, enhancing plant cell transformation efficiency, engineering herbicide resistance, genetically targeting cell ablations, and other methods involving the regulation of cell death in plants.Type: GrantFiled: February 2, 2001Date of Patent: July 29, 2003Assignees: Pioneer Hi-Bred International, Inc., Curators of the University of MissouriInventors: Steven P. Briggs, Gurmukh S. Johal, John Gray
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Patent number: 6600021Abstract: Methods of reducing cystine containing animal and plant proteins, and improving dough and baked goods' characteristics is provided which includes the steps of mixing dough ingredients with a thiol redox protein to form a dough and baking the dough to form a baked good. The method of the present invention preferably uses reduced thioredoxin with wheat flour which imparts a stronger dough and higher loaf volumes. Methods for reducing snake, bee and scorpion toxin proteins with a thiol redox (SH) agent and thereby inactivating the protein or detoxifying the protein in an individual are also provided. Protease inhibitors, including the, Kunitz and Bowman-Birk trypsin inhibitors of soybean, were also reduced by the NADP/thioredoxin system (NADPH, thioredoxin, and NADP-thioredoxin reductase) from either E. coli or wheat germ. When reduced by thioredoxin, the Kunitz and Bowman-Birk soybean trypsin inhibitors lose their ability to inhibit trypsin.Type: GrantFiled: November 23, 1999Date of Patent: July 29, 2003Assignee: The Regents of the University of CaliforniaInventors: Bob B. Buchanan, Karoly Kobrehel, Boihon C. Yee, Joshua H. Wong, Rosa Lozano, Jin-an Jiao, Sungho Shin
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Patent number: 6583271Abstract: Methods of reducing cystine containing animal and plant proteins, and improving dough and baked goods' characteristics is provided which includes the steps of mixing dough ingredients with a thiol redox protein to form a dough and baking the dough to form a baked good. The method of the present invention preferably uses reduced thioredoxin with wheat flour which imparts a stronger dough and higher loaf volumes. Methods for reducing snake, bee and scorpion toxin proteins with a thiol redox (SH) agent and thereby inactivating the protein or detoxifying the protein in an individual are also provided. Protease inhibitors, including the Kunitz and Bowman-Birk trypsin inhibitors of soybean, were also reduced by the NADP/thioredoxin system (NADPH, thioredoxin, and NADP-thioredoxin reductase) from either E. coli or wheat germ. When reduced by thioredoxin, the Kunitz and Bowman-Birk soybean trypsin inhibitors lose their ability to inhibit trypsin.Type: GrantFiled: November 23, 1999Date of Patent: June 24, 2003Assignee: The Regents of the University of CaliforniaInventors: Bob B. Buchanan, Karoly Kobrehel, Boihon C. Yee
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Publication number: 20030060607Abstract: The present invention provides a method for processing defatted oil seeds, comprising the steps of: (a) solubilizing at least a portion of the protein contained in the oil seeds to produce suspended residual solids and a first solution comprising protein, phenolic-protein complexes, and free phenolic compounds; (b) separating at least a portion of the free phenolic compounds from the first solution and recovering a free phenolic reduced solution; and (c) treating the free phenolic reduced solution to precipitate at least a portion of the protein as a precipitated protein isolate and recovering a treated solution containing a soluble protein isolate. Novel protein products are also disclosed. Food and drink products containing the novel protein products are also disclosed.Type: ApplicationFiled: May 28, 2002Publication date: March 27, 2003Inventors: Levente Laszlo Diosady, Lei Xu, Bih-King Chen
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Publication number: 20030013852Abstract: An objective of the invention is to provide a neutral particulate soybean protein having an extremely reduced odor called “soybean odor” which is present in a soybean protein and derived from soybeans and also having an excellent flavor without deteriorating the flavor associated naturally with a processed food product when used in such food. The present invention is a method for producing a neutral soybean protein which comprises heating a soybean protein slurry or solution under acidic conditions followed by neutralization (to pH 6.0 to 8.0) preferably followed by heating again.Type: ApplicationFiled: April 26, 2002Publication date: January 16, 2003Inventors: Tetsuo Sakata, Masahiko Samoto, Yasuo Otani
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Publication number: 20030004114Abstract: The present invention provides a method of inhibiting fungal growth on a growing plant of agricultural or horticultural origin. In a preferred embodiment, an effective amount of a fungal growth inhibiting composition comprising a peptide and a polysaccharide is administered to the plant.Type: ApplicationFiled: May 17, 2002Publication date: January 2, 2003Inventor: Anthony Jabar
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Patent number: 6495342Abstract: The invention relates to a nitrogenous composition resulting from the enzymatic hydrolysis of an aqueous solution of maize gluten, having a ratio of the concentrations of inorganic phosphorus to total phosphorus (Pi/Pt) greater than or equal to 0.05, preferably from 0.05 to 0.5 and a ratio of the concentrations of amine nitrogen to total nitrogen (Na/Nt) greater than or equal to 0.025. The invention also relates to the use of a nitrogenous composition according to the invention in culture media for microorganisms which produce, in particular, organic acid.Type: GrantFiled: February 1, 2001Date of Patent: December 17, 2002Assignee: Roquette FreresInventors: Catherine Fouache, Laurent Seigueilha, Eric Dubois
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Publication number: 20020162142Abstract: The invention relates to the genetic manipulation of organisms, particularly to the expression of P-glycoprotein genes in transformed organisms, preferably plants. Nucleotide sequences for the P-glycoprotein genes, particularly the Br2 gene of maize, and methods for their use are provided. The sequences find use in modifying the growth of organisms, particularly plants.Type: ApplicationFiled: March 19, 2002Publication date: October 31, 2002Applicant: Pioneer Hi-Bred International, Inc.Inventors: Gurmukh S. Johal, Dilbag S. Multani, Steven P. Briggs
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Patent number: 6350590Abstract: The present invention relates to a process for the controlled enzymatic cleavage of purified and depigmented active allergenic proteins from indoor and outdoor source materials, which process produces fragments of allergens that retain the the natural T-lymphocyte stimulating epitopes, but are depleted of IgE-binding B-cell epitopes and complement-activating agents. The invention also relates to the new pharmaceutical products. These allergen fragments do not exhibit the disadvantages of conventional allergenic extracts for immunotherapy and can be safely used to induce a state of specific T-cell anergy and immunological tolerance in allergic human beings.Type: GrantFiled: June 23, 2000Date of Patent: February 26, 2002Assignee: C.B.F. Leti, S.A.Inventors: Lubertus Berrens, Maria Leticia Gonzales Romano, Maria Teresa Gallego Camara
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Patent number: 6326470Abstract: Plant cell expansion is regulated by wall relaxation and yielding, which is thought to be catalyzed by elusive “wall loosening” enzymes. By employing a reconstitution approach, we initially found that a crude protein extract from the cell walls of growing cucumber seedlings possessed the ability to induce the extension of isolated cell walls. This activity was restricted to the growing region of the stem and could induce the extension of isolated cell walls from various dicots and monocots, but was less effective on grass coleoptile walls. Sequential HPLC fractionation of the active wall extract revealed two proteins with molecular masses of 29 and 30 kD, as measured by SDS-PAGE, associated with such activity. Each protein, by itself, could induce wall extension without detectable hydrolytic breakdown of the wall. We proposed the name “expansins” for this class of proteins.Type: GrantFiled: October 28, 1999Date of Patent: December 4, 2001Assignee: The Penn State Research FoundationInventor: Daniel J. Cosgrove