Carboxylic Patents (Class 536/110)
  • Patent number: 10837142
    Abstract: Coating compositions, including high degree of substitution (DS), viscosity optimized starches, are disclosed for use in non-barrier paper coatings. Paper coated with the same is disclosed as well as methods of making the coating compositions and coated papers.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: November 17, 2020
    Assignee: SAPPI NORTH AMERICA, INC.
    Inventors: Joseph M. Fernandez, Arbin Rajbanshi, Qi Wang
  • Patent number: 9458252
    Abstract: A lipophilic starch is provided along with methods of making the same. The starch is prepared by modifying the starch with an organic acid anhydride reagent, such as octenyl succinic anhydride, drying the modified starch to a moisture content of less than 15% by weight, and then heat treating the dried starch at a temperature of at least 100° C. for at least one minute.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: October 4, 2016
    Assignee: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Yong-Cheng Shi, Yanjie Bai
  • Patent number: 9273196
    Abstract: Modeling compounds and methods for making the same are described. The modeling compounds, in some embodiments, comprise about 20% to about 40% by weight starch-based binder, and about 0.15% to about 1.2% by weight microspheres dispersed throughout the compounds. In some embodiments, the modeling compound further comprises vinylpyrrolidone polymers.
    Type: Grant
    Filed: April 12, 2013
    Date of Patent: March 1, 2016
    Assignee: Hasbro, Inc.
    Inventors: Linwood E. Doane, Jr., Lev Tsimberg, Tania Hall
  • Patent number: 8895533
    Abstract: The invention relates to a compound, comprising a) a first starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, wherein the starch derivative has a mean relative molar mass Mw1 and a degree of molar substitution MS1, and b) a second starch derivative selected from the group consisting of hydroxyalkyl starch, carboxyl alkyl starch, ester starch and arbitrary mixtures thereof, having a mean relative molar mass Mw2 and a degree of molar substitution MS2, characterized in that Mw1 is greater than Mw2 (Mw1>Mw2) and MS2 is greater than MS1 (MS2>MS1).
    Type: Grant
    Filed: December 6, 2010
    Date of Patent: November 25, 2014
    Assignee: B. Braun Melsungen AG
    Inventors: Bernd Meier, Iris Theresia Jankowiak-Meier, Nele Meier, Clara Meier
  • Patent number: 8796445
    Abstract: Esterification of a carbohydrate using an acylating agent can effectively be performed using a process comprising: (a) combining the carbohydrate with the acylating agent, (b) adjusting the moisture content of the combination below 40 wt. %, and (c) subjecting the combination to superheated steam. The carbohydrate is especially starch and the acylating agent is in particular an acid, such as an organic acid, amino acid, or diacid.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: August 5, 2014
    Assignee: Nederlandse Organisatie voor Toegepast-Natuurwetenschappelijk Onderzoek TNO
    Inventors: Johannes Wilhelmus Timmermans, Jan Matthijs Jetten, Theodoor Maximiliaan Slaghek, Ingrid Karin Haaksman
  • Publication number: 20140005308
    Abstract: The present invention concerns a method for manufacturing a starch-based plasticized composition comprising starch and a plasticizer said plasticizer comprising 1,3-propanediol (PDO). The invention also concerns a plasticized material comprising the plasticized starch composition of the invention and a polymer.
    Type: Application
    Filed: March 18, 2011
    Publication date: January 2, 2014
    Applicant: METABOLIC EXPLORER
    Inventor: Sophie Macedo Galvaing
  • Publication number: 20130251996
    Abstract: A modified starch material is arranged for biocompatible hemostasis, biocompatible adhesion prevention, tissue healing promotion, absorbable surgical wound sealing and tissue bonding, when applied as a biocompatible modified starch to the tissue of animals. The modified starch material produces hemostasis, reduces bleeding of the wound, extravasation of blood and tissue exudation, preserves the wound surface or the wound in relative wetness or dryness, inhibits the growth of bacteria and inflammatory response, minimizes tissue inflammation, and relieves patient pain. Any excess modified starch not involved in hemostatic activity is readily dissolved and rinsed away through saline irrigation during operation. After treatment of surgical wounds, combat wounds, trauma and emergency wounds, the modified starch hemostatic material is rapidly absorbed by the body without the complications associated with gauze and bandage removal.
    Type: Application
    Filed: May 14, 2013
    Publication date: September 26, 2013
    Inventors: Xin JI, Cheng Xing, Xueshen Shi, Jianping Chen
  • Patent number: 8466277
    Abstract: The invention relates to a method for coupling low-molecular weight substances to a starch-derived modified polysaccharide. The binding interaction between the modified polysaccharide and the low-molecular weight substance is based on a covalent bond which is the result of a coupling reaction between the terminal aldehyde group or a functional group of the modified polysaccharide molecule resulting from the chemical reaction of this aldehyde group and a functional group of the low-molecular weight substance which reacts with this aldehyde group or with the resulting functional group of the polysaccharide molecule. The bond directly resulting from the coupling reaction can be optionally modified by a further reaction to the aforementioned covalent bond. The invention further relates to pharmaceutical compositions that comprise conjugates formed in this coupling process and to the use of said conjugates and compositions for the prophylaxis or therapy of the human or animal body.
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: June 18, 2013
    Assignee: Fresenius Kabi Deutschland GmbH
    Inventors: Michele Orlando, Jurgen Hemberger, Klaus Sommermeyer, Wolfram Eichner, Sven Frie, Katharina Lutterbeck, Cornelius Jungheinrich, Roland Scharpf
  • Patent number: 8410262
    Abstract: This invention covers a novel method for the preparation of hydroxy polymer esters of amino, alkylamino and quaternary ammonium acids and their use in several fields of industry, including the use as additives in the manufacture of paper or paperboard. The esterification of the hydroxy polymer, preferably starch, is performed under semianhydrous conditions by heating homogenized mixtures of the hydroxy polymer and reagents.
    Type: Grant
    Filed: December 7, 2006
    Date of Patent: April 2, 2013
    Assignee: Chemigate Oy
    Inventors: Aki Laine, Hendrik Luttikhedde
  • Patent number: 8399590
    Abstract: A superhydrophilic amphiphilic copolymer and process for making the superhydrophilic amphiphilic copolymer includes a low molecular weight polysaccharide modified with a hydrophobic reagent, such as substituted succinic anhydride. The superhydrophilic amphiphilic copolymer system generates stable foam for use in applications, such as healthcare formulations, with low irritation of the eyes and skin.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: March 19, 2013
    Assignee: Akzo Nobel Chemicals International B.V.
    Inventors: Joseph B. Gardner, Michael J. Fevola, Frank C. Sun, Russel M. Walters
  • Patent number: 8277554
    Abstract: The invention relates to a hot melt adhesive, comprising at least one polysaccharide ester gained by a reaction of a polysaccharide with an imidazolide in melted imidazole. The invention relates, further, to a process for producing the hot melt adhesive, in which imidazole is melted, and an acid chloride and/or an acid anhydride and/or a lactone is reacted in and with the melted imidazole to form an imidazolide, whereby at least one polysaccharide is added to the melted imidazole, whereby the polysaccharide is reacted with the imidazolide to form a polysaccharide ester.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: October 2, 2012
    Assignees: Innovent e.V., Friedrich-Schiller-Universitat
    Inventors: Bernd Grünler, Andreas Heft, Marion Homuth, Thomas Heinze, Tim Liebert
  • Publication number: 20120230928
    Abstract: The present invention relates to compositions containing fat-soluble active ingredients and/or colorants in a matrix based on improved modified polysaccharides, i.e. modified polysaccharides where parts were separated, and to a process for preparing these compositions as well as to these improved modified polysaccharides themselves and a process for the manufacture thereof. The present invention further relates to the use of the compositions of this invention for the to enrichment, fortification and/or for the coloration of food, beverages, animal feed, cosmetics and pharmaceutical compositions and to such food, beverages, animal feed, cosmetics and pharmaceutical compositions themselves.
    Type: Application
    Filed: April 23, 2012
    Publication date: September 13, 2012
    Applicant: DSM IP ASSETS B.V.
    Inventors: David SCHAFFNER, Christian SCHÄFER, Bernd SCHLEGEL
  • Publication number: 20120208897
    Abstract: The present invention relates to a continuous method for preparing acetylated derivatives of an amylaceous material. The invention also relates to a solid composition of at least one acetylated derivative of an amylaceous material obtained by means of said method. The invention finally relates to the use of such a composition to prepare thermoplastic, elastomeric, adhesive, pharmaceutical and/or ink compositions.
    Type: Application
    Filed: October 11, 2010
    Publication date: August 16, 2012
    Applicant: ROQUETTE FRERES
    Inventor: Claude Quettier
  • Publication number: 20120172587
    Abstract: The invention relates to a method for producing polysaccharide esters or polysaccharide mixed esters, in which a polysaccharide or a modified polysaccharide is converted with at least one esterification reagent and at least one halogenide component, an imidazole compound which is generated in situ being used as catalyst.
    Type: Application
    Filed: May 26, 2010
    Publication date: July 5, 2012
    Applicant: Frauhofer-Gesellschaft zur Forderung der Angewandten Forschung E.V.
    Inventors: Bert Volkert, André Lehmann
  • Patent number: 8119792
    Abstract: The invention relates to novel transglycosylation products and their preparation. The transglycosylation products according to the invention are prepared from starch derivatives, such as esters or ethers of starch. The products are obtained by reacting a starch derivative with an alcohol in the presence of an acid catalyst. The forming product is separated by precipitation or by removing any unreacted alcohol by evaporation. In the products according to the invention the good properties of starch derivatives, such as the excellent water resistance of esters, are combined with the versatility of transglycoside products. The products can be used as adhesives, in which case they are formulated, for example as hot-melt adhesives, and as comonomers, prepolymers or macroinitiators in the preparation of polymers.
    Type: Grant
    Filed: February 17, 2003
    Date of Patent: February 21, 2012
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Soili Peltonen, Hannu Mikkonen, Thomas Gädda
  • Publication number: 20120003477
    Abstract: Particles of a polysaccharide derivative, having at least one substituent with conjugated unsaturated bonds and exhibiting an index of refraction in excess of 1.50 and a method for the production thereof. In the method, the raw-material is suspended in an organic solvent to form a suspension, which is contacted with an organic reactant comprising a residue with conjugated unsaturated bonds; the raw-material and the organic reactant are reacted to form a derivative exhibiting ester or ether bond between the raw-material and the residue with conjugated unsaturated bonds; the polysaccharide derivative is dissolved in a solvent to form a solution; and the solution is contacted with a non-solvent to precipitate particles of the polysaccharide derivative invention provides lightweight, optically improved organic pigments and fillers based on renewable resources and which are recyclable by combustion or composting.
    Type: Application
    Filed: December 30, 2009
    Publication date: January 5, 2012
    Applicant: TEKNOLOGIAN TUTKIMUSKESKUS VTT
    Inventors: Hannu Mikkonen, Kaisa Putkisto, Soili Peltonen, Sari Hyvärinen, Kimmo Koivunen
  • Publication number: 20110287165
    Abstract: A lipophilic starch is provided along with methods of making the same. The starch is prepared by modifying the starch with an organic acid anhydride reagent, such as octenyl succinic anhydride, drying the modified starch to a moisture content of less than 15% by weight, and then heat treating the dried starch at a temperature of at least 100° C. for at least one minute.
    Type: Application
    Filed: February 3, 2010
    Publication date: November 24, 2011
    Applicant: KANSAS STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Yong-Chen Shi, Yanjie Bai
  • Publication number: 20110262586
    Abstract: A chewing gum base which is cud-forming and chewable at mouth temperature contains water-insoluble highly substituted starch short chain carboxylate. The highly substituted starch short chain carboxylate may be plasticized to function as an elastomer in the gum base.
    Type: Application
    Filed: December 18, 2009
    Publication date: October 27, 2011
    Applicant: WM. WRIGLEY JR. COMPANY
    Inventor: Jingping Liu
  • Publication number: 20110124746
    Abstract: The present invention relates to a starch emulsifier product prepared by sufficiently solubilizing a starch and subsequently sufficiently derivatizing the sufficiently solubilized starch product, in one embodiment by reacting the sufficiently solubilized starch with an alkenyl succinic anhydride. Such starch emulsifier products are useful as emulsifying and/or encapsulating agents, particularly in systems where high load and retention of the active ingredient, low surface oil exposure, and excellent oxidation resistance is desired.
    Type: Application
    Filed: November 25, 2009
    Publication date: May 26, 2011
    Applicant: National Starch & Chemical Company
    Inventors: Ralph Trksak, Afaf Makarious
  • Patent number: 7829600
    Abstract: The present invention relates to a starch emulsifier product prepared by sufficiently solubilizing a starch and subsequently sufficiently derivatizing the sufficiently solubilized starch product, in one embodiment by reacting the sufficiently solubilized starch with an alkenyl succinic anhydride. Such starch emulsifier products are useful as emulsifying and/or encapsulating agents, particularly in systems where high load and retention of the active ingredient, low surface oil exposure, and excellent oxidation resistance is desired.
    Type: Grant
    Filed: January 14, 2010
    Date of Patent: November 9, 2010
    Assignee: Brunob II B.V.
    Inventors: Ralph Trksak, Afaf Makarious
  • Publication number: 20090270606
    Abstract: This invention covers a novel method for the preparation of hydroxy polymer esters of amino, alkylamino and quaternary ammonium acids and their use in several fields of industry, including the use as additives in the manufacture of paper or paperboard. The esterification of the hydroxy polymer, preferably starch, is performed under semianhydrous conditions by heating homogenized mixtures of the hydroxy polymer and reagents.
    Type: Application
    Filed: December 7, 2006
    Publication date: October 29, 2009
    Inventors: Aki Laine, Hendrik Luttikhedde
  • Patent number: 7247722
    Abstract: Polysaccharide aldehydes are prepared using selective oxidation involving the use of nitroxyl radical mediated aqueous oxidation with a limited amount of oxidant and defined reaction conditions. These polysaccharide aldehyde derivatives having maximum effective aldehyde and minimal carboxylic acid levels making them especially useful as wet, temporary wet and dry strength additives for paper.
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: July 24, 2007
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: A. Levent Cimedoglu, John S. Thomaides
  • Patent number: 7135557
    Abstract: A method of making a carboxylated carbohydrate is disclosed, cellulose being a preferred carbohydrate material. Carboxylated cellulose fibers can be produced whose fiber strength and degree of polymerization is not significantly sacrificed. The method involves the use of a catalytic amount of a hindered cyclic oxammonium compounds as a primary oxidant and chlorine dioxide as a secondary oxidant in an aqueous environment. The oxammonium compounds may be formed in situ from their corresponding amine, hydroxylamine, or nitroxyl compounds. The oxidized cellulose may be stabilized against D.P. loss and color reversion by further treatment with an oxidant such as sodium chlorite or a chlorine dioxide/hydrogen peroxide mixture. Alternatively it may be treated with a reducing agent such as sodium borohydride. In the case of cellulose the method results in a high percentage of carboxyl groups located at the fiber surface.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: November 14, 2006
    Assignee: Weyerhaeuser Company
    Inventors: S. Ananda Weerawarna, Joseph Lincoln Komen, Richard A. Jewell
  • Patent number: 7109325
    Abstract: A method of making a carboxylated carbohydrate is disclosed, cellulose being a preferred carbohydrate material. Carboxylated cellulose fibers can be produced whose fiber strength and degree of polymerization is not significantly sacrificed. The method involves the use of a catalytic amount of a hindered cyclic oxammonium compounds as a primary oxidant and chlorine dioxide as a secondary oxidant in an aqueous environment. The oxammonium compounds may be formed in situ from their corresponding amine, hydroxylamine, or nitroxyl compounds. The oxidized cellulose may be stabilized against D.P. loss and color reversion by further treatment with an oxidant such as sodium chlorite or a chlorine dioxide/hydrogen peroxide mixture. Alternatively it may be treated with a reducing agent such as sodium borohydride. In the case of cellulose the method results in a high percentage of carboxyl groups located at the fiber surface.
    Type: Grant
    Filed: August 30, 2004
    Date of Patent: September 19, 2006
    Assignee: Weyerhaeuser Company
    Inventors: Joseph Lincoln Komen, S. Ananda Weerawarna, Richard A. Jewell
  • Patent number: 6919447
    Abstract: A method of making a carboxylated carbohydrate is disclosed, cellulose being a preferred carbohydrate material. Carboxylated cellulose fibers can be produced whose fiber strength and degree of polymerization is not significantly sacrificed. The method involves the use of a catalytic amount of a hindered cyclic oxammonium compounds as a primary oxidant and chlorine dioxide as a secondary oxidant in an aqueous environment. The oxammonium compounds may be formed in situ from their corresponding amine, hydroxylamine, or nitroxyl compounds. The oxidized cellulose may be stabilized against D.P. loss and color reversion by further treatment with an oxidant such as sodium chlorite or a chlorine dioxide/hydrogen peroxide mixture. Alternatively it may be treated with a reducing agent such as sodium borohydride. In the case of cellulose the method results in a high percentage of carboxyl groups located at the fiber surface.
    Type: Grant
    Filed: June 6, 2001
    Date of Patent: July 19, 2005
    Assignee: Weyerhaeuser Company
    Inventors: Joseph Lincoln Komen, S. Ananda Weerawarna, Richard A. Jewell
  • Patent number: 6884885
    Abstract: The process entails increasing the concentration of cyclodextrin to 15% (w/w) and above to form complexes through a precipitation process in order to increase the yield of complexes, increase the amount of guest complexed, and decrease the particle size of the complex.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: April 26, 2005
    Assignee: Cerestar Holding B.V.
    Inventor: Helena Qi
  • Patent number: 6852852
    Abstract: A method of producing a cellueose ether that is predominantly substituted in the C2 position of the anhydroglucose unit of the cellulose is described. The regioselectively substituted saccharide ester produced according to the method of the present invention is selected from the group consisting of oligo-saccharide ester and polysaccharide ester, having a partial average degree of substitution (AS) at the C2 position of its anhydroglucose unit of at least 90% relative to the total AS. Also described is a blood plasma expander comprising the regioselectively substituted ester.
    Type: Grant
    Filed: October 17, 2002
    Date of Patent: February 8, 2005
    Assignee: Wolff Walsrode AG
    Inventors: Erik-Andreas Klohr, Wolfgang Koch, Dieter Klemm, René Dicke
  • Publication number: 20040158059
    Abstract: The present invention relates to a new process in 3 steps starting from 2-C-methyl-D-ribopentono-1,4-lactone for the preparation of tetra-acyl ribofuranose derivatives of formula (I): 1
    Type: Application
    Filed: May 27, 2003
    Publication date: August 12, 2004
    Inventors: Giancarlo Tamerlani, Liana Salsini, Ilaria Lombardi, Debora Bartalucci, Giovanni Cipolletti
  • Publication number: 20040013710
    Abstract: Hydrolyzable tannin extracts from plants are provided which have activity to prevent bacterial adherence to surfaces. Methods for prevention and treatment of urinary tract and kidney infections in animals and humans are provided.
    Type: Application
    Filed: June 18, 2003
    Publication date: January 22, 2004
    Inventor: Amy B. Howell
  • Publication number: 20030220270
    Abstract: The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to a method of preparation thereof. A mono- and disaccharide derivatives according to the invention comprises at least one fatty acid ester and may further comprise one or more anionic groups and are useful for, inter alia, medical, pharmaceutical, cosmetic and food applications.
    Type: Application
    Filed: October 7, 2002
    Publication date: November 27, 2003
    Inventors: Lucas Alfonsus T. Hilgers, Anneke Georgine Blom
  • Patent number: 6627752
    Abstract: Starch lactide derivatives and the preparation of such derivatives wherein starch is reacted with lactide in an aqueous caustic media. Another embodiment involves the extrusion of the starch lactide derivatives to form starch based foam products having increased flexibility, strength and compatibility.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: September 30, 2003
    Assignee: National Starch and Chemical Investment Holding Company
    Inventors: Robert L. Billmers, David S. Roesser
  • Publication number: 20030173045
    Abstract: The present invention relates to a liquid starch dispersion for paper coating where the dispersion has 5 to 50 percent by weight of starch, and the starch contains from 20 to 100 percent by weight of at least one cationic starch. The liquid starch composition is characterized in that a 25 percent by weight starch solids dispersion has a 25° C. viscosity of from 500 to 2500 cps both initially, and also upon storage at room temperature for 90 days. The dispersion preferably contains a blend of cationic starch and ASA starch. The liquid starch dispersion is useful in paper and paperboard coating processes, as a rheology modifier, a structurant, and/or a binder, all at the same time. The liquid starch dispersion provides good coating holdout, gloss, and stiffness properties. The cationic nature of the starch coating improves printability with anionic inks, and makes the coatings useful for ink-jet and photographic papers.
    Type: Application
    Filed: March 18, 2002
    Publication date: September 18, 2003
    Inventors: Philip Confalone, Daniel B. Solarek, Aqnieszka Lapinska, Wayne Kibble
  • Patent number: 6605715
    Abstract: Process for the preparation of a starch ester, in particular a starch acetate, wherein a starch-based feedstock is reacted with an organic carboxylic acid anhydride in the presence of a catalyst. The reaction of the starch-based feedstock and the anhydride is performed at an excess pressure of about 0.1 to 50 bar in an essentially anhydrous medium containing 10% by weight of water at the most. As catalyst, sodium acetate, sodium hydroxide or sulphuric acid is used, and as the reaction medium, acetic acid or excess acetanhydride is used. By means of the invention, the duration of the esterification reaction can be significantly shortened, the separation of the product can be facilitated, and the recirculation of the waste solutions can be rendered more efficient.
    Type: Grant
    Filed: August 18, 1999
    Date of Patent: August 12, 2003
    Assignee: Valtion Teknillinen Tutkimuskeskus
    Inventors: Geert Lammers, Pertti Tiitola, Jani Vuorenpää
  • Patent number: 6596860
    Abstract: The invention relates to an adhesive composition comprising a derivative of a starch, which comprises at least 95 wt. % of amylopectin, based on dry substance of the starch, wherein the derivative is obtainable by cross-linking, etherification, esterification or a combination thereof, of the starch. The invention further relates to a process for preparing the adhesive composition and to the use thereof for adhering wallpaper or billposter to a substrate.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: July 22, 2003
    Assignee: Cooperatieve Verkoop-en Productievereniging van Aardappelmeel en Derivaten AVEBE B.A.
    Inventors: Ronald Peter W. Kesselmans, Ido Pieter Bleeker, Willem Kamminga
  • Publication number: 20030069402
    Abstract: The invention relates to a process for the production of peracylated 1-O-glycosides of general formula I or salts thereof 1
    Type: Application
    Filed: July 11, 2002
    Publication date: April 10, 2003
    Applicant: Schering AG
    Inventors: Johannes Platzek, Klaus-Dieter Graske, Ulrich Niedballa
  • Publication number: 20030054055
    Abstract: Method for obtaining tannin by extracting plant resources with mangrove, acacia, pine, eucalyptus, oak, hemlock and the like with lower alcohol or lower alcohol/water, or extracting outer bark of radiata pine (Pinus radiata) with water, lower alcohol or lower alcohol/water, and an adhesive containing said extracted substance for adhering woody materials such as veneer.
    Type: Application
    Filed: March 19, 2002
    Publication date: March 20, 2003
    Applicant: Kabushiki Kaisha Juken Sangyo
    Inventors: Yusho Nakamoto, Toshihiko Tsunoda, Keiko Ono, Naoko Kageyama, Yoshikazu Yazaki, Huijian Jiang, Frank Lawson, Peter Heinz Theodore Uhlherr
  • Publication number: 20030050252
    Abstract: An active ingredient from the group of an antihistamine, a decongestant, an antitussive or anticholinergic is dissolved in a suitable solvent and added to a dispersion of tannic acid in water to form the tannate salt complex of the active ingredient. The active ingredient tannate salt complex without isolation or purification is then added to a liquid or semi-solid medium composed of thickening, suspending, coloring, sweetening and flavoring agents, with stirring. Thereafter, preservatives, pH-adjusting and anti-caking agents in a suitable solvent are mixed with the liquid or semi-solid medium to generate a therapeutic dosage form.
    Type: Application
    Filed: April 9, 2002
    Publication date: March 13, 2003
    Inventors: Jeffrey S. Kiel, H. Greg Thomas, Narasimhan Mani
  • Publication number: 20020193315
    Abstract: Roselipin derivatives which are represented by the following formula: 1
    Type: Application
    Filed: March 14, 2002
    Publication date: December 19, 2002
    Inventors: Satoshi Omura, Hiroshi Tomoda
  • Patent number: 6489468
    Abstract: A regioselectively substituted member selected from the group consisting of oligo-saccharide ester and polysaccharide ester is disclosed. The ester has a partial average degree of substitution AS at the C2 position of its anhydroglucose unit of at least 90% relative to the total AS. Also disclosed is a method of producing the regioselectively substituted ester. The method entails reacting in the presence of a catalyst a dissolved or a highly swollen oligo-saccharide or polysaccharide with an esterification reagent.
    Type: Grant
    Filed: February 29, 2000
    Date of Patent: December 3, 2002
    Assignee: Wolff Walsrode AG
    Inventors: Erik-Andreas Klohr, Wolfgang Koch, Dieter Klemm, René Dicke
  • Publication number: 20020123624
    Abstract: A hydrophobically esterified starch, is disclosed, having the general formula: 1
    Type: Application
    Filed: February 23, 2001
    Publication date: September 5, 2002
    Inventors: Lei Qiao, Qu-Ming Gu, H. N. Cheng
  • Patent number: 6387853
    Abstract: Polymers are derivatized and then may be introduced into a wellbore, such as in a hydraulic fracturing treatment. A polymer may be a guar powder that is mixed with a organic solvent and derivatized using a derivatizing agent, such as sodium chloroacetate. The polymer is typically derivatized in bulk prior to introduction into the wellbore. The derivatized polymer may be hydrated and/or crosslinked prior to introduction into the wellbore.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: May 14, 2002
    Assignee: BJ Services Company
    Inventors: Jeffrey C. Dawson, Subramanian Kesavan, Hoang V. Le
  • Patent number: 6369215
    Abstract: The invention concerns a hydroxypropyl starch ester (HPS ester), compositions containing it, and a process for the preparation thereof. According to the invention, the molar substitution in the HPS ester is 2 at the most and the substitution degree in the ester group is at least 1. The HPS ester is prepared by hydroxypropylating a starch-containing base material in an aqueous alkanol medium. A starch component can be prepared of the HPS ester containing 90 to 60% by weight HPS ester and 10 to 40% by weight of a plasticizer. Compositions which are suited for, e.g., coating board or paper and for use as a component in labelling adhesives or paint, can be made from the starch component by combining it with auxiliaries known as such within the polymer and plastics technology.
    Type: Grant
    Filed: August 19, 1999
    Date of Patent: April 9, 2002
    Assignee: Valtion teknillinen tutkimuskeskus
    Inventors: Soili Peltonen, Pertti Tiitola, Jani Vuorenp{umlaut over (aa)}, Harri Happonen, Pertti Törmälä
  • Publication number: 20010037018
    Abstract: The invention covers a process to manufacture biodegradable starch esters which can be processed into extrudates, formed parts and sheeting. The starch is activated with a carboxylic acid/carboxylic anhydride mixture through partial swelling and the onsetting esterification reaction at simultaneous conversion of the water entrained in the starch and partially esterified with a carboxylic anhydride up to the desired degree of substitution with progressing swelling and disintegration.
    Type: Application
    Filed: February 22, 1999
    Publication date: November 1, 2001
    Inventors: ROLF KAKUSCHKE, INNO RAPTHEL, HARTMUT STOYE, GUNTER SCHMOZ
  • Patent number: 6222031
    Abstract: Disclosed is a process for preparing a water-soluble tricarboxypolysaccharide which includes the step of oxidizing an &agr;-bonding type polysaccharide with a ruthenium compound and an oxidizing agent. The water-soluble tricarboxypolysaccharide, having a high carboxyl group content, can easily and inexpensively be prepared in a high yield without any problem of a post-treatment after the reaction, and thus the present invention is desirable as an industrial preparation process of the water-soluble tricarboxpolysaccharide.
    Type: Grant
    Filed: January 27, 1998
    Date of Patent: April 24, 2001
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Hidechika Wakabayashi, Toru Takahashi, Masaru Sakamoto, Rieko Sano
  • Patent number: 6096524
    Abstract: High solids maltodextrin syrups, some of which are useful as the base for remoistenable adhesives, are prepared by a high solids alpha amylase enzyme conversion process. They are characterized by their high solids content (at least 55 wt. %) and light color. A granular chemically derivatized, optionally converted, starch having a degree of substitution of greater than about 0.01 and less than about 0.5 is used as the starting material. The maltodextrins have a reducing sugar content of about 5-19 dextrose equivalent and a distinct polymodal molecular weight distribution. When a granular highly esterified starch (D.S. of 0.5-1.8) is used as the starting material in the high solids process, the resulting enzyme-converted, esterified maltodextrins are characterized by their improved water dispersibility.
    Type: Grant
    Filed: May 14, 1998
    Date of Patent: August 1, 2000
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Yong-Cheng Shi, James L. Eden, James J. Kasica
  • Patent number: 6063914
    Abstract: The aging of swellable starch maleates is reduced by reacting with one or more singly and/or multiply functional nucleophiles as in a Michael condensation reaction. Mixtures of mercaptoethanol and 1,2-bis-(2-mercaptoethoxy)-ethane or mixtures of sodium bisulfite and pentaerythrite-tetrakis-(2-mercaptoacetate) are preferred. The decrease of the retention capacity [SRV] in the reaction products after 100 days is preferably <10%. The products find use as biodegradable, non-aging superabsorbers.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: May 16, 2000
    Assignee: Stockhausen GmbH & Co. KG
    Inventors: Heiko Wolf, Klaus Dorn, Thomas Eurich
  • Patent number: 6037466
    Abstract: A method for preparing hydrophobic starch derivatives wherein starch and an anhydride are reacted in a slurry with the anhydride reagent being added to the slurry in pre-emulsified form to provide a significantly faster and more efficient reaction.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: March 14, 2000
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Walter Maliczyszyn, Jeffrey G. Atkinson, Maria Tolchinsky
  • Patent number: 6011149
    Abstract: The present invention relates to photochemically cross-linked derivatives of general formulae (IA) and (IB), wherein R is a polysaccharide radical in which the OH groups have been esterified as OR' groups or converted into a carbamate (urethane), R.sub.1, and R.sub.2 are each independently lower alkyl or unsubstituted or substituted aryl, X is a direct bond or phenylene, m is 0 or 1, and n is 0 or an integer from 1 to 20, to processes from the preparation thereof and to the use thereof. The compounds of general formula (IA) and (IB) can be used as supports in the chromatographic separation of enantiomers.
    Type: Grant
    Filed: September 2, 1997
    Date of Patent: January 4, 2000
    Assignee: Novartis AG
    Inventor: Eric Francotte
  • Patent number: 6008345
    Abstract: There is described a polycarboxylic acid or a salt thereof obtained by oxidation of a polysaccharide containing an anhydrous glucose as a constituent unit, wherein the carboxyl group content thereof is high and the weight average molecular weight thereof is not less than 2000. This polycarboxylic acid is suitable for use as a builder for detergent because the amount of an alkali required to perform neutralization titration of the polycarboxylic acid is not less than 435 mg in terms of sodium hydroxide and because the chelate force thereof to a polyvalent cation is high.The polycarboxylic acid is produced by oxidizing a polysaccharide with an oxidizing agent in the presence of a transition metal catalyst.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: December 28, 1999
    Assignee: Lion Corporation
    Inventors: Yukihiro Dannoue, Kiyoshi Morohara, Kiyoshi Nakayama
  • Patent number: 6001473
    Abstract: Release coating compositions comprising:a) a starch ester release agent having an ester component of 2 to 8 carbon atoms and a degree of substitution (DS) of from 1.0 to 2.2;b) a hydrophobic plasticizer; andc) water.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: December 14, 1999
    Assignee: National Starch and Chemical Investment Holding Corporation
    Inventors: Jeffrey G. Atkinson, Robert L. Billmers, Susan W. Graham, Charles J. Gzemski