Additional Chalcogen Attached Directly Or Indirectly To The Diazine Ring By Nonionic Bonding Patents (Class 544/314)
  • Patent number: 4868187
    Abstract: Nucleoside analogues having a ring-open structure, of general formula: ##STR1## where R and R' may be hydrogen, silyl groups, substituted alkyl groups, benzyl groups and the like, and X is an optionally substituted base such as guanine or adenine, have been shown to exhibit anti-viral and other biological acivities at non-toxic levels.
    Type: Grant
    Filed: March 9, 1987
    Date of Patent: September 19, 1989
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Kelvin K. Ogilvie
  • Patent number: 4863927
    Abstract: 1-[2-(Hydroxymethyl)cycloalkylmethyl]-5-substituted uracils which are herpes simplex viral thymidine kinase inhibitors, their acyl derivatives, and their pharmaceutically-acceptable salts; pharmaceutical formulations containing these compounds; the treatment of DNA viral, particularly herpes viral, infections with these compounds; methods of preparing these compounds; and novel intermediates useful in their preparation.
    Type: Grant
    Filed: May 11, 1987
    Date of Patent: September 5, 1989
    Assignee: Merck & Co., Inc.
    Inventors: Richard L. Tolman, Wallace T. Ashton
  • Patent number: 4859229
    Abstract: The invention is concerned with 3-aryluracils of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are as described herein, as well as salts thereof and their manufacture, weed control compositions which contain such compounds as the active substance and the use of the active substances or compositions for weed control. The invention is also concerned with herbicidally-active starting materials and weed control compositions containing these.
    Type: Grant
    Filed: July 21, 1987
    Date of Patent: August 22, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean Wenger, Paul Winternitz
  • Patent number: 4833252
    Abstract: Substituted N-phenylsulfonyl-N'-pyrimidinylureas and N-phenylsulfonyl-N'-triazinylureas of the general formula ##STR1## and the salts thereof with amines, alkali metal bases or alkaline earth metal bases, or with quaternary ammonium bases, have good pre- and postemergence selective herbicidal and growth regulating properties.In the above formula the symbols have the following meanings:R.sup.1 is hydrogen, halogen, nitro, cyano, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.1 -C.sub.4 alkylsulfinyl, --CO--R.sup.8, --NR.sup.9 R.sup.10, --CO--NR.sup.11 R.sup.12 or --SO.sub.2 --NR.sup.13 R.sup.14,R.sup.2 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfinyl or C.sub.1 -C.sub.4 alkylsulfonyl,R.sup.3 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl or cyano,R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl,R.sup.5 is hydrogen, C.sub.
    Type: Grant
    Filed: September 28, 1988
    Date of Patent: May 23, 1989
    Assignee: Ciba-Geigy Corporation
    Inventors: Werner Topfl, Georg Pissiotas
  • Patent number: 4831106
    Abstract: A low-formaldehyde binder consists essentially of(A) from 5 to 80% by weight of a water-soluble condensation product of carbonyl number 0-200 which has been prepared by alkaline condensation from 0.1 to 0.4 mole of an aliphatic or cycloaliphatic condensable ketone and 1 mole of formaldehyde, and(B) from 20 to 95% by weight of 4,5-dihydroxyimidazolidin-2-one and/or an unetherified, partially etherified or completely etherified condensation product thereof with an aliphatic monoaldehyde or dialdehyde.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: May 16, 1989
    Assignee: BASF Aktiengesellschaft
    Inventors: Fritz E. Kempter, Franz Matejcek, Werner Neubach, Gerd Busse
  • Patent number: 4798893
    Abstract: A method for the synthesis of the 2-propanone (I) is described starting from alkoxide (II) through the lactone (IV). ##STR1## Excellent control of the location of the substitution on the phenyl ring is achieved and the reaction proceeds in high yield.
    Type: Grant
    Filed: September 21, 1987
    Date of Patent: January 17, 1989
    Assignee: McNeilab, Inc.
    Inventors: David A. Cherry, Cynthia A. Maryanoff, John E. Mills, Roy A. Olofson, James D. Rodgers
  • Patent number: 4777180
    Abstract: Novel esters in all stereoisomeric forms and mixtures of said isomers of the formula ##STR1## wherein one of X and Y is ##STR2## and the other is selected from the group consisting of --CH.sub.2 --, --CH.sub.2 --CH.sub.2 -- and --CH.sub.2 --CH.sub.2 --CH.sub.2 --, n is an integer from 2 to 3 and R.sub.1 is selected from the group consisting of alkyl of 1 to 3 carbon atoms and alkenyl and alkynyl of 2 to 3 carbon atoms having pesticidal activity.
    Type: Grant
    Filed: October 7, 1987
    Date of Patent: October 11, 1988
    Assignee: Roussel Uclaf
    Inventors: Jean Tessier, Pierre Girault
  • Patent number: 4760163
    Abstract: The disclosure is concerned with novel 3-aryluracils of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X have the significances given in the description, as well as salts thereof and their manufacture, weed control compositions which contain such compounds as active ingredients and the use of the active ingredients or compositions for the control of weeds. The disclosure also concerns certain herbicidally active starting materials and weed control compositions containing these as active ingredients.
    Type: Grant
    Filed: January 25, 1988
    Date of Patent: July 26, 1988
    Assignee: Hoffmann-LaRoche Inc.
    Inventors: Jean Wenger, Paul Winternitz
  • Patent number: 4747866
    Abstract: A pirimidinyloxyalkanamide derivative of Formula 1: ##STR1## wherein R.sub.1 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkylthio group, a lower alkenylthio group, a lower alkynylthio group, a halogenated lower alkenylthio group, a cycloalkylthio group, an aroxyalkylthio group, a lower alkoxyl group, an amino group, a methanesulfonyl group, a trifluoromethyl group, an anilino group which may be substituted with a halogen atom or a benzylthio group which may be substituted with a halogen atom; R.sub.2 represents a hydrogen atom, a halogen atom, a lower alkyl group, a trifluoromethyl group, an amino group, a lower alkoxy group or a lower alkylthio group; R.sub.3 represents an ethyl group or an n-propyl group; and R.sub.
    Type: Grant
    Filed: August 15, 1986
    Date of Patent: May 31, 1988
    Assignee: Ube Industries, Ltd.
    Inventors: Tetsuo Takematsu, Yasutomo Takeuchi, Mitsuaki Takenaka, Seiji Takamura, Hiroshi Hase
  • Patent number: 4748245
    Abstract: A process for the preparation of phenylthiopyrimidines which comprises: (a) reacting a thiopyrimidine; with sulfuryl chloride in the presence of a suitable solvent to form the sulfenyl chloride of said thiopyrimidine; (b) reacting said sulfenyl chloride of said thiopyrimidine with a phenol or substituted phenol, optionally in the presence of a Friedal-Crafts catalyst, to form a thiopyrimidinyl phenol; and (c) reacting said thiopyrimidinylphenol formed in step (b) with a base and an alkylating agent to form the end product.
    Type: Grant
    Filed: March 20, 1986
    Date of Patent: May 31, 1988
    Assignee: Stauffer Chemical Company
    Inventor: Donald R. James
  • Patent number: 4746352
    Abstract: The disclosure is concerned with novel 3-aryluracils of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and X have the significances given in the description, as well as salts thereof and their manufacture, weed control compositions which contain such compounds as active ingredients and the use of the active ingredients or compositions for the control of weeds. The disclosure also concerns certain herbicidally active starting materials and weed control compositions containing these as active ingredients.
    Type: Grant
    Filed: March 10, 1986
    Date of Patent: May 24, 1988
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jean Wenger, Paul Winternitz
  • Patent number: 4719214
    Abstract: There are disclosed compounds having the formula: ##STR1## wherein R is a group having the formula --C.tbd.CSi(CH.sub.3).sub.3, --C.tbd.CH, --CH.dbd.CH.sub.2, --CH.sub.2 CH.sub.2 Si(CH.sub.3).sub.3 or --CH.sub.2 X; X is bromo, chloro or iodo; and R' is hydrogen or an acyl group, with the proviso that when R is --CH.sub.2 X, R' is an acyl group. Certain of these compounds are active in inhibiting the replication of DNA viruses. Other of these compounds are useful as intermediates in the production of compounds which are active in inhibiting the replication of DNA viruses.
    Type: Grant
    Filed: July 25, 1985
    Date of Patent: January 12, 1988
    Assignee: Southern Research Institute
    Inventors: Y. Fulmer Shealy, C. Allen O'Dell
  • Patent number: 4708732
    Abstract: Herbicidal compounds having the formula ##STR1## wherein R.sup.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, phenyl or substituted phenyl;R.sup.2 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.1 and R.sup.2 together are C.sub.2 -C.sub.5 alkylene;R.sup.3 is hydrogen, C.sub.1 -C.sub.4 alkyl, phenyl or substituted phenyl, with the proviso that R.sup.1 and R.sup.3 are not both phenyl or substituted phenyl;R.sup.4 is hydrogen or C.sub.1 -C.sub.4 alkyl; orR.sup.3 and R.sup.4 together are oxo;R.sup.5 is hydrogen or C.sub.1 -C.sub.4 alkyl;R.sup.6 is hydrogen or C.sub.1 -C.sub.4 alkyl; andR.sup.7 and R.sup.8 independently are (1) hydrogen; (2) halogen; (3) C.sub.1 -C.sub.4 alkyl; (4) C.sub.1 -C.sub.4 alkoxy; (5) trifluoromethoxy; (6) cyano; (7) nitro; (8) C.sub.1 -C.sub.4 haloalkyl; (9) R.sup.b SO.sub.n -- wherein n is the integer 0, 1 or 2; and R.sup.b is (a) C.sub.1 -C.sub.4 alkyl; (b) C.sub.1 -C.sub.4 alkyl substituted with halogen or cyano; (c) phenyl; or (d) benzyl; (10) --NR.sup.c R.sup.d wherein R.sup.c and R.sup.
    Type: Grant
    Filed: October 24, 1986
    Date of Patent: November 24, 1987
    Assignee: Stauffer Chemical Company
    Inventor: Charles G. Carter
  • Patent number: 4666627
    Abstract: Novel 4-heterocyclylvinyl-4'-styryl-biphenyls of the formula ##STR1## are described, i which A is an isoxazolyl, oxadiazolyl, pyrimidinyl or triazinyl radical which is unsubstituted or substituted by a non-chromophoric substituent, R.sub.1 is hydrogen or a non-chromophoric substituent and R.sub.2 is hydrogen, halogen, or alkyl; processes for the preparation of these compounds are also described.The novel 4-heterocyclylvinyl-4'-styryl-biphenyls can be used as fluorescent brighteners for high-molecular organic materials, in particular materials of polyamide and polyester, especially for polyester textiles.
    Type: Grant
    Filed: July 27, 1984
    Date of Patent: May 19, 1987
    Assignee: Ciba-Geigy Corporation
    Inventor: Hans R. Meyer
  • Patent number: 4625029
    Abstract: Cyclic urea/glyoxal/polyol condensates are excellent formaldehyde-free crosslinking resins for cellulosic textile fabrics and insolubilizers for binders in paper coating compositions.
    Type: Grant
    Filed: March 13, 1985
    Date of Patent: November 25, 1986
    Assignee: Sun Chemical Corporation
    Inventors: William C. Floyd, Bernard F. North
  • Patent number: 4625028
    Abstract: This invention relates to selected hydrogenated 5,6-dihydro-6-aryluracils.
    Type: Grant
    Filed: July 11, 1983
    Date of Patent: November 25, 1986
    Assignee: The Upjohn Company
    Inventor: Herman W. Smith
  • Patent number: 4623730
    Abstract: 4-Amino-3-imidazolin-2-one and (2-methoxy-2-iminoethyl)urea are valuable intermediates for the production of pharmacologically active compounds.
    Type: Grant
    Filed: February 21, 1984
    Date of Patent: November 18, 1986
    Assignee: Diamalt Aktiengesellschaft
    Inventors: Siegfried Maeke, Adolf Bauer, Hubert Vogt, Helmut Wolf
  • Patent number: 4613604
    Abstract: A compound of the Formula (I): ##STR1## where X is a benzyl group or a benzyloxybenzyl group and pharmaceutical preparations containing the same.
    Type: Grant
    Filed: July 31, 1985
    Date of Patent: September 23, 1986
    Assignee: Brown University Research Foundation
    Inventors: Shih H. Chu, Paul Calabresi, Ming Y. W. Chu, Mahmoud H. el Kouni, Fardos N. M. Naguib, Sungman Cha
  • Patent number: 4590189
    Abstract: The compound of the formula ##STR1## wherein X is a cyclic group which may optionally be substituted; Y is a carboxyl group which may optionally be esterified or amidated; Z is --CH.dbd.CH--CH.dbd.CH--, --S--(CH.sub.2).sub.l --S--(l is an integer of 1 to 3), --N.dbd.CH--CH.dbd.N-- or --(CH.sub.2).sub.m --(m is an integer of 3 to 5); ring A may optionally be substituted with halogen, nitro, amino, alkanoylamino, alkoxycarbonyl, carboxyl or carbamoyl; and n is an integer of 1 to 3, and salts thereof. The compounds display a strong antianxiety effect to mammalian animals and are useful for the prevention or treatment of a disease such as psychosomatic disease and anxiety neurosis.
    Type: Grant
    Filed: March 24, 1983
    Date of Patent: May 20, 1986
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Kentaro Hiraga, Yoshiaki Saji
  • Patent number: 4476306
    Abstract: 2,4-Dihydroxypyrimidine (uracil) is prepared from alkali formyl acetic acid ester by reaction with thiourea, heating with chloroacetic acid, and heating with acids.
    Type: Grant
    Filed: July 23, 1982
    Date of Patent: October 9, 1984
    Assignee: Dynamit Nobel AG
    Inventor: Hermann Peeters
  • Patent number: 4455424
    Abstract: The present invention relates to naphthoquinone derivatives of formula I, ##STR1## in which R.sub.1 signifies a halogen atom, a nitro group or an unsubstituted or substituted alkoxy or amino group,R.sub.2 signifies the atoms necessary to form an unsaturated ring system, which ring system has 1 or 2 nuclei and is unsubstituted or substituted,R.sub.3 signifies an unsubstituted or substituted s-triazinyl or pyrimidyl radical, andn is 0, 1 or 2,which compounds are free from sulphonic acid groups are useful as pigments or disperse dyes.
    Type: Grant
    Filed: February 24, 1977
    Date of Patent: June 19, 1984
    Assignee: Sandoz Ltd.
    Inventor: Bansi L. Kaul
  • Patent number: 4443435
    Abstract: Novel, transient prodrug forms of biologically active agents containing mercapto groups have (i) the structural formula (I): ##STR1## wherein X is O, S, or NR.sup.5 ;R.sup.1 S is the residue of any biologically active agent R.sup.1 SH;R.sup.
    Type: Grant
    Filed: November 12, 1981
    Date of Patent: April 17, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Nicholas S. Bodor, Kenneth B. Sloan, Stefano A. Pogany
  • Patent number: 4427437
    Abstract: A process of inhibiting the growth of, severely damaging, or killing plants which process comprises applying to the plant or to the growth medium thereof an effective amount of a composition comprising as active ingredient a compound of formula I: ##STR1## wherein A, B and D are independently chosen from the group consisting of hydrogen, halogen, hydroxy, nitro, cyano, thiocyano, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkoxy, optionally substituted alkenyloxy, optionally substituted alkynyloxy, optionally substituted alkylthio, optionally substituted cycloalkyl, optionally substituted amino, optionally substituted phenyl, carboxy, alkoxycarbonyl, optionally substituted carbamoyl, sulfo, alkylsulfonyl and optionally substituted sulfamoyl; R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.
    Type: Grant
    Filed: September 5, 1978
    Date of Patent: January 24, 1984
    Assignee: ICI Australia Limited
    Inventors: Alexander Serban, Keith G. Watson, Richard B. Warner
  • Patent number: 4415573
    Abstract: Novel uracil derivatives of the formula ##STR1## (wherein R.sub.1, R.sub.2 R.sub.3 and X are defined in the description) and their pharmaceutically acceptable salts, process for preparing the same and pharmaceutical composition containing the same are disclosed. The uracil derivatives have good antitumor activity and, therefore, are useful as antitumor preparation.
    Type: Grant
    Filed: August 10, 1981
    Date of Patent: November 15, 1983
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Kiyoshige Ochi, Katsuhito Miyamoto, Hiroki Mitsui, Yumiko Tsuruma, Isao Matsunaga, Takashi Matsuno, Shigeru Takanashi, Minoru Shindo
  • Patent number: 4400508
    Abstract: Novel orotic acid derivatives useful as agricultural chemicals or intermediates thereof are disclosed. The orotic acid derivatives are represented by the formula ##STR1## where Me is an alkali metal, R.sup.1 is an alkyl group of from 1 to 4 carbon atoms, an allyl group, a cyclohexyl group, a benzyl group, or a group ##STR2## (where R.sup.2 is an alkyl group of from 1 to 4 carbon atoms, an alkoxyl group of from 1 to 4 carbon atoms or a halogen atom and n is 0, 1, 2 or 3), m is an integer of 1 or 2, and X is a chlorine, bromine or iodine atom or a group --COR.sup.0 (where R.sup.0 is an alkyl group of from 1 to 4 carbon atoms or a phenyl group) when m is 1, and a group --COO.sup.- when m is 2.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: August 23, 1983
    Assignee: UBE Industries, Ltd.
    Inventors: Kiyoshi Fukui, Noboru Kakeya, Hiroshi Jibiki, Fumio Matsuo
  • Patent number: 4396623
    Abstract: There is provided a method for the treatment of viral infections by treating a host animal with a pharmaceutically effective amount of a carbocyclic analog of a nucleoside represented by Formula I: ##STR1## wherein X is chlorine, bromine, iodine, a lower alkyl group or an amino group of the formula --NHR.sup.2 wherein R.sup.2 is a lower alkyl group; and R and R' can be the same or different members selected from the group consisting of hydrogen, an alkanoyl group or an aroyl group.
    Type: Grant
    Filed: August 26, 1981
    Date of Patent: August 2, 1983
    Assignee: Southern Research Institute
    Inventors: Y. Fulmer Shealy, C. Allen O'Dell, William M. Shannon
  • Patent number: 4358591
    Abstract: Novel 1-phenyl-3-polyhaloalkyl or polyhalovinyl uracils, and synthesis thereof, which are useful biological agents.
    Type: Grant
    Filed: July 21, 1980
    Date of Patent: November 9, 1982
    Assignee: Zoecon Corporation
    Inventor: Gustave K. Kohn
  • Patent number: 4329460
    Abstract: New derivatives of the formula: ##STR1## (wherein X is O or NH; R.sub.1 is --OH which may optionally be etherified or esterified, etherified mercapto or --NH.sub.2 which may optionally be substituted; R.sub.2 and R.sub.3, respectively, mean H, lower alkyl or ##STR2## and Y is an esterified or amidated carboxyl group, or CN). These derivatives are produced, by fluorination of corresponding 1,2,3,4-tetrahydro-2,4-dioxopyrimidine compounds and can be converted into 5-fluorouracil derivatives under hydrolytic conditions. The new derivatives are able to prolong the lives of animals having carcinomas or have antiviral activity.
    Type: Grant
    Filed: June 13, 1979
    Date of Patent: May 11, 1982
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Osamu Miyashita, Koichi Matsumura, Hiroshi Shimadzu, Naoto Hashimoto
  • Patent number: 4296158
    Abstract: Information-carrying discs are comprised of a substrate having an information bearing layer derived from 15 to 100% by weight of at least one polyacryloyl-containing heterocyclic monomer.
    Type: Grant
    Filed: February 1, 1980
    Date of Patent: October 20, 1981
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Terry W. Lewis
  • Patent number: 4292286
    Abstract: A cyclic urea reaction product forms as a by-product of a hindered amine acid gas scrubbing process and results in an ultimate buildup of the material in the circulating amine scrubbing solution. The buildup of this material has a deleterious effect on acid gas removal rates and accordingly, results in inefficient acid gas removal. In the process of the present invention, the cyclic urea degradation product is removed from the circulating solution by employing a selective precipitation of the cyclic urea followed by filtration. The selective precipitation is carried out by cooling the circulating solution to a particular temperature level such that the cyclic urea comes out of solution while the other components remain in solution.
    Type: Grant
    Filed: December 11, 1979
    Date of Patent: September 29, 1981
    Assignee: Exxon Research & Engineering Co.
    Inventors: Geoffrey R. Say, James R. Hays, Sr., Jagannathan N. Iyengar
  • Patent number: 4283548
    Abstract: Object of the invention are new diisatoic acid and triisatoic acid derivatives of the general formula I ##STR1## wherein n represents 2 or 3, X stands for oxygen or sulfur and R for a group of the general formula IIY--Z--B].sub.m, (II)in which m stands for 1 or 2, Y for B when m is 1 and Y further represents a di- or trivalent alkyl group with 1 to 5 carbon atoms when m is 2, B represents alkylene with 1 to 4 carbon atoms and Z stands for phenylene-1,4-dioxy or diphenylene-4,4'-dioxy optionally singly or multiply substituted by Cl, NO.sub.2 or alkyl or for a 5- to 7-membered heterocyclic ring which is optionally substituted by one or more of said substituents and has one or more atoms selected from the group consisting of N, S and O as members of the ring, with a benzene nucleus optionally being annulated to said ring, and a process for the production of these compounds which is characterized in that a compound of the general formula IIIR--XH).sub.
    Type: Grant
    Filed: April 10, 1979
    Date of Patent: August 11, 1981
    Assignee: Lim-Holding S.A
    Inventors: Walter Sibral, Oskar Schmidt
  • Patent number: 4266056
    Abstract: Phenyl uracils, synthesis and intermediates therefor, and compositions for the control of pests, especially fungi and bacteria.
    Type: Grant
    Filed: March 23, 1979
    Date of Patent: May 5, 1981
    Assignees: Zoecon Corporation, Imperial Chemical Industries Limited
    Inventors: Clive A. Henrick, Jeffrey N. Labovitz, Roland T. V. Fox, William G. Rathmell, Margaret C. Shephard
  • Patent number: 4262121
    Abstract: Novel hexahydropyrimid-4-yl ethers and a process for the preparation of hexahydropyrimid-4-yl ethers by reacting hexahydropyrimidines with alcohols at above 110.degree. C.The hexahydropyrimid-4-yl ethers obtainable by the process of the invention are valuable starting materials for the preparation of dyes, pesticides and assistants for use in textile chemistry, surface-coating resin chemistry and the timber industry.
    Type: Grant
    Filed: October 24, 1979
    Date of Patent: April 14, 1981
    Assignee: BASF Aktiengesellschaft
    Inventor: Harro Petersen
  • Patent number: 4262072
    Abstract: Abrasion resistant coatings are comprised of a crosslinked polymeric coating comprising at least 15% by weight of said polymer derived from a polyacrylate material having a heterocyclic nucleus therein.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: April 14, 1981
    Assignee: Minnesota Mining and Manufacturing Company
    Inventors: Larry A. Wendling, John B. Covington
  • Patent number: 4256656
    Abstract: The invention relates to an organic compound having an enantiotropic or monotropic mesomorphous phase.
    Type: Grant
    Filed: October 29, 1979
    Date of Patent: March 17, 1981
    Assignee: Thomson-CSF
    Inventors: Alain Beguin, Jean-Claude Dubois, Annie Zann
  • Patent number: 4249011
    Abstract: Ethylenically unsaturated crosslinking agents and polymerizable monomers are disclosed. These agents contain a heterocyclic nucleus and are capable of forming oxygen insensitive, radiation curable systems.
    Type: Grant
    Filed: June 25, 1979
    Date of Patent: February 3, 1981
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Larry A. Wendling
  • Patent number: 4239888
    Abstract: Compounds of the formula ##STR1## wherein R is ##STR2## and their utility as coccidiostats.
    Type: Grant
    Filed: November 4, 1974
    Date of Patent: December 16, 1980
    Assignee: Pfizer Inc.
    Inventor: Max W. Miller
  • Patent number: 4180548
    Abstract: A cyclic urea reaction product forms as a by-product of a hindered amine acid gas scrubbing process and results in an ultimate buildup of the material in the circulating amine scrubbing solution. The buildup of this material has a deleterious effect on acid gas removal rates and accordingly, results in inefficient acid gas removal. In the process of the present invention, the cyclic urea degradation product is removed from the circulating solution by employing a selective precipitation of the cyclic urea followed by filtration. The selective precipitation is carried out by cooling the circulating solution to a particular temperature level such that the cyclic urea comes out of solution while the other components remain in solution.
    Type: Grant
    Filed: December 22, 1978
    Date of Patent: December 25, 1979
    Assignee: Exxon Research & Engineering Co.
    Inventors: Geoffrey R. Say, James R. Hays, Sr., Jagannathan N. Iyengar
  • Patent number: 4171429
    Abstract: There is provided a novel process for pyrimidine to pyrimidine transformations by the displacement of the 1,2,3-portion of a pyrimidine by a 1,3-ambident nucleophile. The novel process requires that the 1 and 3 nitrogens of the pyrimidine moiety be substituted. The novel process makes available, inter alia, novel uracils, simple methods of radioisotopically labeling pyrimidine nuclei, a simple and inexpensive method of preparing the important antiviral and antileukemic material pseudoisocytidine and its new active analog 2'-deoxypseudoisocytidine.
    Type: Grant
    Filed: March 29, 1977
    Date of Patent: October 16, 1979
    Assignee: Research Corporation
    Inventors: Kyoichi A. Watanabe, Kosaku Hirota, Chung K. Chu, Uri Reichman, Jack J. Fox
  • Patent number: 4161594
    Abstract: New dialcohols of mononuclear, five-membered or six-membered, unsubstituted or substituted N-heterocyclic compounds which contain two NH-groups in the molecule, by reaction of mononuclear, five-membered or six-membered, unsubstituted or substituted N-heterocyclic compounds, for example hydantoin, barbituric acid, uracil, dihydrouracil, parabanic acid and the corresponding derivatives, with ethylene oxide or propylene oxide to give dialcohols. These diols are useful as intermediates for the preparation of polymers, such as polyesters or polyurethanes, or of epoxy resins.
    Type: Grant
    Filed: January 17, 1975
    Date of Patent: July 17, 1979
    Assignee: Ciba-Geigy AG
    Inventors: Hans Batzer, Jurgen Habermeier, Daniel Porret
  • Patent number: 4161603
    Abstract: Dicarboxylic acids or dicarboxylic acid esters, containing a N,N-heterocyclic radical, of the formula ##STR1## in which the two R.sub.1 independently of one another each denote hydrogen, an alkyl with 1 to 4 C atoms or a phenyl, the two R.sub.2 independently of one another each denote hydrogen or an alkyl with 1 to 10 C atoms, the two n represent identical or different numbers from 2 to 12 and X denotes a divalent monocyclic N,N-heterocyclic radical of benzimidazolone, parabanic acid, 2,2-dimethylimidazolidine-4,5-dione, 6-ethyluracil or barbituric acid are prepared by reacting 1 mol of the corresponding N,N-heterocyclic compounds with 2 mols of a compound of the formula ##STR2## wherein Y.sub.1 denotes a chlorine or bromine atom. The dicarboxylic acid compounds have a high stability to heat and therefore are very suited for the manufacture of polycondensates by the melt condensation process.
    Type: Grant
    Filed: May 6, 1977
    Date of Patent: July 17, 1979
    Assignee: Ciba-Geigy Corporation
    Inventor: Jurgen Habermeier
  • Patent number: 4159378
    Abstract: A novel and very elegant method is proposed for the preparation of N.sub.1 -(2-tetrahydrofuryl)-5-substituted or -unsubstituted uracil, especially, N.sub.1 -(2-tetrahydrofuryl)-5-fluorouracil, by the reaction of the corresponding 5-substituted uracil compound with 2,3-dihydrofuran. The reaction is performed in the presence of a chlorosilane compound, e.g. dimethyldichlorosilane, and a catalytic amount of an organic amine compound and can proceed very rapidly without disadvantageous side reactions to give the objective compound with high purity in a high yield.
    Type: Grant
    Filed: March 8, 1978
    Date of Patent: June 26, 1979
    Assignee: Toshin Chemical Co., Ltd.
    Inventors: Kenichi Ishibashi, Susumu Ishiguro, Reiko Komaki
  • Patent number: 4150228
    Abstract: The present invention is concerned with novel compounds useful as photographic silver halide complexing agents and with their photographic use. The subject compounds are represented by the formulas ##STR1## wherein one of R.sup.1 and R.sup.2 is --CH.sub.2).sub.x SR.sup.3 and the other of said R.sup.1 and R.sup.2 is --CH.sub.2).sub.y SR.sup.3 wherein R.sup.3 is alkyl, x is a whole number 0 or 1 and y is a whole number from 0 to 5.
    Type: Grant
    Filed: June 30, 1977
    Date of Patent: April 17, 1979
    Assignee: Polaroid Corporation
    Inventor: Richard B. Greenwald
  • Patent number: 4146531
    Abstract: Compounds of the formula I ##STR1## wherein A is alkylidene or optionally alkylated vinylene, B is a group of the formula II ##STR2## wherein R.sub.1 and R.sub.2 are alkyl, R.sub.3, R.sub.4 and R.sub.5 are hydrogen or alkyl and n is 0, 1 or 2 and m is 1 or 2, and X is identical to B if m equals 1 or X is methylene if m equals 2, as stabilizers for organic material.
    Type: Grant
    Filed: January 9, 1978
    Date of Patent: March 27, 1979
    Assignee: Ciba-Geigy Corporation
    Inventors: Siegfried Rosenberger, Andreas Schmidt
  • Patent number: 4145546
    Abstract: The compounds are substituted isocytosines which are histamine H.sub.2 -antagonists. Two specific compounds of the present invention are 2-?2-(5-methyl-4-imidazolylmethylthio)-ethylamino!-5-(3-methoxybenzyl)-4-p yrimidone and 2-?2-(5-methyl-4-imidazolylmethylthio)ethylamino!-5-benzyloxy-4-pyrimidone .
    Type: Grant
    Filed: September 21, 1977
    Date of Patent: March 20, 1979
    Assignee: Smith Kline & French Laboratories Limited
    Inventors: Thomas H. Brown, Graham J. Durant, John C. Emmett, Charon R. Ganellin
  • Patent number: 4130560
    Abstract: New dicarboxylic acid derivatives containing a N,N-heterocyclic radical are obtained by reacting 1 mol of a cyclic ureide, such as 1,1-methylene-bis-hydantoin, benzimidazolone, parabanic acid, 6-methyluracil or 2,2-diethylbarbituric acid, with 2 mols of 4-halogenomethylbenzoic acid derivatives. The new dicarboxylic acid derivatives are valuable monomers for the manufacture of stable plastics. Thus, the dicarboxylic acid dialkyl esters, for example, can be converted by means of diols into polyesters with valuable mechanical properties.
    Type: Grant
    Filed: November 20, 1975
    Date of Patent: December 19, 1978
    Assignee: Ciba-Geigy Corporation
    Inventor: Jurgen Habermeier
  • Patent number: 4125516
    Abstract: Alkylthioalkanoyloxyalkyl and alkylthioalkyl derivatives of N-heterocyclic moieties are stabilizers for organic materials subject to oxidative, thermal and/or light induced deterioration. They are prepared by classical transesterification, oxirane ring opening and addition of mercaptan to olefin reactions. Typical embodiments are tris[2-(3-n-dodecythiopropionyloxy)ethyl isocyanurate] and 3-(3-n-dodecylthio-2-hydroxypropyl)-5,5-dimethylhydantoin. These compounds are used in conjunction with phenolic antioxidants to stabilize organic materials, particularly polyolefins and hydrocarbon compositions, against the deleterious effects of heat and oxygen and against discoloration.
    Type: Grant
    Filed: January 17, 1977
    Date of Patent: November 14, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: Martin Dexter, David H. Steinberg
  • Patent number: 4125720
    Abstract: Process for the preparation of a 4-chloro-5-alkoxycarbonyl-2-methoxy-pyrimidine of the formula: ##STR1## IN WHICH R.sub.
    Type: Grant
    Filed: April 12, 1977
    Date of Patent: November 14, 1978
    Assignee: Laboratoire Roger Bellon
    Inventors: Marcel E. Pesson, Suzanne W. Geiger
  • Patent number: 4124760
    Abstract: Diepoxides which may be photopolymerized in the presence or absence of a photosensitizer contain a group having conjugated unsaturation attached to a nitrogen heterocycle, such as a hydantoin or barbituric acid residue, forming part of an advanced diepoxide. The resultant photopolymer may be crosslinked by heating in the presence of a curing agent for epoxide resins.The diepoxides are of use in the production of printing plates and printed circuits, especially multilayer printed circuits.
    Type: Grant
    Filed: July 13, 1977
    Date of Patent: November 7, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: George E. Green, Bernard P. Stark, John S. Waterhouse
  • Patent number: RE31533
    Abstract: Information-carrying discs are comprised of a substrate having an information bearing layer derived from 15 to 100% by weight of at least one polyacryloyl-containing heterocyclic monomer.
    Type: Grant
    Filed: December 3, 1982
    Date of Patent: March 6, 1984
    Assignee: Minnesota Mining and Manufacturing Company
    Inventor: Terry W. Lewis