Heptacyclo Ring System Having The Six-membered Hetero Ring As One Of The Cyclos Patents (Class 546/33)
  • Patent number: 10294381
    Abstract: The present disclosure is drawn to a pigment-based inkjet ink and methods. The inkjet ink includes water; from 2 wt % to 9 wt % pigment solids; from 0.05 wt % to 2 wt % of an acetylenic diol non-ionic surfactant; from 0.05 wt % to 2 wt % of a second surfactant. The second surfactant can be a polysorbate having at least 50% lipophilic oleic acid groups and having an HLB value of less than 15, or a C12-C18 polyoxyethylene glycol ether having an ethylene oxide number less than 20, or a perfluoropolyether including a polyethylene glycol primary alcohol or diol. The inkjet ink also includes from 5 wt % to 50 wt % of an organic solvent system comprising triethylene glycol and a cyclic amide.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: May 21, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Sterling Chaffins, Kevin P. DeKam, Jayprakash C. Bhatt, Larrie Deardurff, Cory J. Ruud, Matthew Thornberry
  • Patent number: 9809601
    Abstract: The material for forming an underlayer film for lithography of the present invention contains a compound having a structure represented by the following general formula (1). (in formula (1), each X independently represents an oxygen atom or a sulfur atom, R1 represents a single bond or a 2n-valent hydrocarbon group having 1 to 30 carbon atoms, the hydrocarbon group may have a cyclic hydrocarbon group, a double bond, a hetero atom or an aromatic group having 6 to 30 carbon atoms, R2 represents a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, an alkenyl group having 2 to 10 carbon atoms, or a hydroxyl group, m is an integer of 0 to 3, n is an integer of 1 to 4, p is 0 or 1, and q is an integer of 1 to 100.).
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: November 7, 2017
    Assignee: Mitsubishi Gas Chemical Company, Inc.
    Inventors: Masatoshi Echigo, Takashi Makinoshima, Naoya Uchiyama
  • Publication number: 20140088130
    Abstract: The present invention relates to a novel hexahydrodibenzo[a,g]quinoline compound represented by general formula (I) and its derivatives, enantiomer, diastereoisomer, raceme and mixtures thereof, as well as pharmaceutically acceptable salts thereof. The present invention further relates to a method for preparing the compound, and the compound has good prevention and treatment effect on neurological diseases, especially diseases associated with dopamine receptor and 5-hydroxytryptamine receptor. The bioactivity experiment demonstrates that, the compound is expected to be developed into a novel and potent chemical entity for treating diseases associated with dopamine receptor and 5-hydroxytryptamine receptor, especially schizophrenia, Parkinson's disease, drug addiction, migraine and so on.
    Type: Application
    Filed: November 27, 2013
    Publication date: March 27, 2014
    Applicant: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES
    Inventors: Hong LIU, Xin XIE, Xuechu ZHEN, Haifeng SUN, Jing LI, Liyuan ZHU, Zeng LI, Ying CHEN, Hualiang JIANG, Kaixian CHEN
  • Patent number: 8658665
    Abstract: This invention pertains generally to processes, uses, methods and materials utilizing particular xanthylium compounds, including compounds of formula (I) and (II), as further defined herein. These compounds are useful as drugs, for example, in the treatment of tauopathies, such as Alzheimer's disease.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: February 25, 2014
    Assignee: WisTa Laboratories Ltd.
    Inventors: Scott Clunas, John Mervyn David Storey, Janet Elizabeth Rickard, David Horsley, Charles Robert Harrington, Claude Michel Wischik
  • Patent number: 8501948
    Abstract: A rylene-based polychromophore of the general formula I in which the variables are each defined as follows: rylene is a radical of the formula which has been functionalized by at least one imide group, ester group or amide group and which may additionally be substituted by aryloxy, arylthio, hetaryloxy and/or hetarylthio; X is a rylenedicarboximide radical which absorbs at a different wavelength from the rylene radical, is bonded to the X radical in the peri-position via Y via a moiety —Y?-A-Y—, is bonded to the rylene radical and may likewise be substituted by aryloxy, arylthio, hetaryloxy and/or hetarylthio; A is a bridging member having at least one aromatic or heteroaromatic radical, the Y or Y and Y? groups being bonded to the aromatic or heteroaromatic radical; Y is a moiety Y? is a moiety where the moieties (i) and (ii) may be part of the ester groups of the rylene radical and the moieties (iii) are part of the imide groups of the rylene radical and the moieties (iv) ar
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: August 6, 2013
    Assignee: BASF Aktiengesellschaft
    Inventor: Martin Konemann
  • Publication number: 20130026422
    Abstract: The present invention relates to a compound according to formula (I), to the use thereof in an electronic device and to an electronic device which comprises one or more compounds according to formula (I).
    Type: Application
    Filed: March 16, 2011
    Publication date: January 31, 2013
    Applicant: Merck Patent GmbH
    Inventors: Amir Hossain Parham, Christof Pflumm
  • Publication number: 20120012824
    Abstract: Disclosed is a metal complex compound represented by the following Chemical Formula 1, and an organic light emitting diode device including the same. In Chemical Formula 1, M, R1 to R8, A1 to A6, and y are the same as defined in the detailed description.
    Type: Application
    Filed: June 24, 2011
    Publication date: January 19, 2012
    Applicant: Samsung Mobile Display Co., Ltd.
    Inventors: Hamada Yuji, Kwan-Hee Lee
  • Patent number: 8017776
    Abstract: Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in high yield, do not require the use of activated intermediates and/or toxic compounds and are readily amenable to scale-up.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: September 13, 2011
    Assignee: XenoPort, Inc.
    Inventors: Laxminarayan Bhat, Mark A. Gallop
  • Patent number: 7816519
    Abstract: The present invention describes novel dyes, including coumarins, rhodamines, and rhodols that incorporate additional fused aromatic rings. The dyes of the invention absorb at a longer wavelength than structurally similar dyes that do not possess the fused aromatic rings. Many of the dyes of the invention are useful fluorescent dyes. The invention includes chemically reactive dyes, dye-conjugates, and the use of such dyes in staining samples and detecting ligands or other analytes.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: October 19, 2010
    Assignee: Life Technologies Corporation
    Inventors: Zhenjun Diwu, Jixiang Liu, Kyle Gee
  • Patent number: 7662987
    Abstract: Disclosed herein are methods for synthesizing 1-(acyloxy)-alkyl prodrug derivatives of drugs through oxidation of 1-acyl-alkyl derivatives of drugs under anhydrous reaction conditions. The methods typically proceed stereospecifically, in high yield, do not require the use of activated intermediates and/or toxic compounds and are readily amenable to scale-up.
    Type: Grant
    Filed: July 15, 2004
    Date of Patent: February 16, 2010
    Assignee: XenoPort, Inc.
    Inventors: Laxminarayan Bhat, Mark A. Gallop
  • Patent number: 7473782
    Abstract: This invention relates to novel fluorinated dyes or colorants having high solubility and low viscosity in halogenated, especially fluorinated, solvents. The dyes or colorants of the present invention improve the performance of electrophoretic displays.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: January 6, 2009
    Assignee: Sipix Imaging, Inc.
    Inventors: Jin Yang, Ying-Syi Li, Haiyan Gu, Yajuan Chen
  • Patent number: 7408062
    Abstract: Disclosed are analogues of trimethine cyanine dyes, which are useful for importing fluorescent properties to target materials by covalent and non-covalent association.
    Type: Grant
    Filed: January 27, 2003
    Date of Patent: August 5, 2008
    Assignee: Carnegie Mellon University
    Inventors: Alan S. Waggoner, Ratnakar B. Mujumdar
  • Patent number: 7390901
    Abstract: This invention relates to novel fluorinated dyes or colorants having high solubility and low viscosity in halogenated, especially fluorinated, solvents. The dyes or colorants of the present invention have shown to improve the performance of electrophoretic displays.
    Type: Grant
    Filed: July 29, 2004
    Date of Patent: June 24, 2008
    Assignee: SiPix Imaging, Inc.
    Inventors: Jin Yang, Kai-Chia Feng, Ying-Syi Li, HongMei Zang, Hong Wang, Chien-Hung Chou, Rong-Chang Liang
  • Publication number: 20080122428
    Abstract: The present invention relates to a method of determining voltage changes, e.g. in cell membranes, by means of a voltage-sensitive dye.
    Type: Application
    Filed: June 25, 2004
    Publication date: May 29, 2008
    Applicant: Max-Planck-Gesellschaft zur Forderungder Wissenschaften e. V.
    Inventors: Bernd Kuhn, Winfried Denk, Gerd Hubener, Peter Fromherz
  • Publication number: 20040266753
    Abstract: A compound selected from those of formula (I): 1
    Type: Application
    Filed: June 18, 2004
    Publication date: December 30, 2004
    Inventors: Michel Koch, Francois Tillequin, Sylvie Michel, John Hickman, Alain Pierre, Stephane Leonce, Bruno Pfeiffer, Pierre Renard
  • Patent number: 6403311
    Abstract: The invention relates to methods and products for analyzing polymers. The polymers are analyzed by reconstructing sequence information from population data sets. The data sets include information about polymer dependent impulses arising from the polymers. The invention is also a method for linearly analyzing polymers by assessing the intensity of a signal arising from the polymer. The signal is generated as units and/or units specific markers pass a fixed station. The quantitative intensity of the signal is proportional to the number of units and/or unit specific markers giving rise to the signal.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: June 11, 2002
    Assignee: US Genomics
    Inventor: Eugene Y. Chan
  • Patent number: 6326153
    Abstract: Dibenzorhodamine compounds having the structure are disclosed, including nitrogen and aryl-substituted forms thereof. In addition, two intermediates useful for synthesizing such compounds are disclosed, a first intermediate having the structure including nitrogen- and aryl-substituted forms thereof, and a second intermediate having the structure including nitrogen- and aryl-substituted forms thereof, wherein substituents at positions C-14 to C18 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alkyl, carboxylic acid, sulfonic acid, —CH2OH, alkoxy, phenoxy, linking group, and substituted forms thereof. The invention further includes energy transfer dyes comprising the dibenzorhodamine compounds, nucleosides labeled with the dibenzorhodamine compounds, and nucleic acid analysis methods employing the dibenzorhodamine compounds.
    Type: Grant
    Filed: February 14, 2001
    Date of Patent: December 4, 2001
    Assignee: The Perkin-Elmer Corporation
    Inventors: Scott C. Benson, Joe Y. L. Lam, Steven Michael Menchen
  • Patent number: 6221606
    Abstract: Dibenzorhodamine compounds having the structure are disclosed, including nitogen- and aryl-substituted forms thereof. In addition, two intermediates useful for synthesizing such compounds are disclosed, a first intermediate having the structure including nitrogen- and aryl-substituted forns thereof, and a second intermediate having the structure including nitrogen- and aryl-substituted forms thereof, wherein substituents at positions C-14 to C18 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alky, carboxylic acid, sulfonic acid, —CH2OH, alkoxy, phenoxy, linking group, and substituted forms thereof. The invention further includes energy transfer dyes comprising the dibenzorhodamine compounds, nucleosides labeled with the dibenzorhodamine compounds, and nucleic acid analysis methods employing the dibenzorhodamine compounds.
    Type: Grant
    Filed: April 20, 2000
    Date of Patent: April 24, 2001
    Assignee: The Perkin-Elmer Corporation
    Inventors: Scott C. Benson, Joe Y. L. Lam, Steven Michael Menchen
  • Patent number: 6051719
    Abstract: Dibenzorhodamine compounds having the structure ##STR1## are disclosed, including nitogen- and aryl-substituted forms thereof. In addition, intermediates useful for synthesizing such compounds are disclosed, such intermediates having the structure ##STR2## In Formula I, R.sub.1 is H or ##STR3## wherein Y is H, lower alkyl, lower alkene, lower alkyne, aromatic, phenyl, polycyclic aromatic, heterocycle, water-solubilizing group, or linking group, including substituted forms thereof. When R.sub.1 is H, the C-12-bonded nitrogen and the C-12 and C-13 carbons form a first ring structure having from 4 to 7 members, and/or the C-12-bonded nitrogen and the C-11 and C-12 carbons form a second ring structure having from 5 to 7 members. The compounds of Formula I further include aryl- and nitrogen-substituted forms thereof.
    Type: Grant
    Filed: November 17, 1998
    Date of Patent: April 18, 2000
    Assignee: The Perkin-Elmer Corporation
    Inventors: Scott Conrad Benson, Joe Y. L. Lam, Krishna Gajanan Upadhya, Peggy Ann Radel, Weiguo Zhen, Steven Michael Menchen
  • Patent number: 5936087
    Abstract: Dibenzorhodamine compounds having the structure ##STR1## are disclosed, including nitogen- and aryl-substituted forms thereof. In addition, two intermediates useful for synthesizing such compounds are disclosed, a first intermediate having the structure ##STR2## including nitrogen- and aryl-substituted forms thereof, and a second intermediate having the structure ##STR3## including nitrogen- and aryl-substituted forms thereof, wherein substituents at positions C-14 to C18 taken separately are selected from the group consisting of hydrogen, chlorine, fluorine, lower alkyl, carboxylic acid, sulfonic acid, --CH.sub.2 OH, alkoxy, phenoxy, linking group, and substituted forms thereof. The invention further includes energy transfer dyes comprising the dibenzorhodamine compounds, nucleosides labeled with the dibenzorhodamine compounds, and nucleic acid analysis methods employing the dibenzorhodamine compounds.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: August 10, 1999
    Assignee: The Perkin-Elmer Corporation
    Inventors: Scott C. Benson, Joe Y. L. Lam, Steven Michael Menchen
  • Patent number: 5861411
    Abstract: A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and Alzheimer's disease, since it has an action of directly activating malfunctioned cholinergic neuron.
    Type: Grant
    Filed: April 10, 1996
    Date of Patent: January 19, 1999
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Kunihiro Ninomiya, deceased, Ken-ichi Saito, Mamoru Sugano, Akihiro Tobe, Yasuhiro Morinaka, Tomoko Bessho, Haruko Harada
  • Patent number: 5536728
    Abstract: A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and Alzheimer's disease, since it has an action of directly activating malfunctioned cholinergic neuron.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: July 16, 1996
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Kunihiro Ninomiya, deceased, Ken-ichi Saito, Mamoru Sugano, Akihiro Tobe, Yasuhiro Morinaka, Tomoko Bessho, Haruko Harada
  • Patent number: 5397785
    Abstract: A novel 4-acylaminopyridine derivative represented by the following formula (I) is disclosed. ##STR1## The 4-acylaminopyridine derivative of the present invention is useful as a medicine for treating disturbances of memory such as senile dementia and Alzheimer's disease, since it has an action of directly activating malfunctioned cholinergic neuron.
    Type: Grant
    Filed: September 2, 1993
    Date of Patent: March 14, 1995
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Kunihiro Ninomiya, deceased, Ken-ichi Sato, Mamoru Sugano, Akihiro Tobe, Yasuhiro Morinaka, Tomoko Bessho, Haruko Harada
  • Patent number: 5316906
    Abstract: Novel fluorescent precipitating substrates made from a class of fluorophores, generally including quinazolinones (quinazolones), benzimidazoles, benzothiazoles, benzoxazoles, quinolines, indolines, and phenanthridines, having the general formula: ##STR1## where carbon atoms of --C.sup.1 .dbd.C.sup.2 -- are further joined so as to complete a first 5- or 6-membered aromatic ring which may contain at least one of the hetero atoms N, O or S,where carbon atoms of --C.sup.4 --N.dbd.C.sup.3 -- are further joined so as to complete a second 5- or 6-membered aromatic ring that contains at least the nitrogen between C.sup.3 and C.sup.4 and may contain at least one additional hetero atom N, O or S,where the first and second aromatic rings may be joined by a 5- or 6-membered bridging ring that contains at least the C.sup.2 from the first aromatic ring and the C.sup.
    Type: Grant
    Filed: August 23, 1991
    Date of Patent: May 31, 1994
    Assignee: Molecular Probes, Inc.
    Inventors: Richard P. Haugland, Yu-zhong Zhang, Stephen T. Yue, Ewald Terpetschnig, Nels A. Olson, John J. Naleway, Karen D. Larison, Zhijian Huang
  • Patent number: 4739064
    Abstract: Selective hydrogenation of the unsaturated nitrogen-containing ring in heterocyclic aromatic compounds is promoted by the use of at least one hydrogenation catalyst selected from the group consisting of nickel, cobalt, palladium, platinum, ruthenium and rhodium in the presence of reaction modifiers exemplified by carbon monoxide, carbon disulfide and hydrogen sulfide.
    Type: Grant
    Filed: December 4, 1985
    Date of Patent: April 19, 1988
    Assignee: Phillips Petroleum Company
    Inventor: James E. Shaw
  • Patent number: 4739063
    Abstract: Selective hydrogenation of the unsaturated nitrogen-containing ring in heterocyclic aromatic compounds is promoted by the use of hydrogenation catalysts selected from the group consisting of iridium, iridium dioxide, rhenium, molybdenum oxide, tungsten oxide, chromium trioxide, ferric oxide, iron pentacarbonyl, cobalt oxide-molybdenum oxide and copper chromite.
    Type: Grant
    Filed: December 4, 1985
    Date of Patent: April 19, 1988
    Assignee: Phillips Petroleum Company
    Inventor: James E. Shaw
  • Patent number: 4451398
    Abstract: Dyes of the formula ##STR1## where R.sup.1 is hydrogen, C.sub.1 -C.sub.6 -alkyl or C.sub.2 -C.sub.6 -alkenyl, R.sup.2 and R.sup.3 independently of one another are hydrogen, C.sub.1 -C.sub.5 -alkyl or C.sub.2 -C.sub.5 -alkenyl, R.sup.4 is C.sub.1 -C.sub.12 -alkyl or hydroxy-C.sub.2 -C.sub.4 -alkyl, X.sup..crclbar. is one equivalent of an anion, mis from 0 to 5 and n is from 0 to 5, with 1.ltoreq.(m+n).ltoreq.5, and F is an (m+n)-valent radical of a monoazo dye, a disazo dye, a polyazo dye, a quinophthalone, a bis-dioxazine, a compound of the 5,6-arylo-2-pyrone series, a naphtholactam dye, a triphenylmethane dye, a xanthene dye, a phthalocyanine, an indigoid, an anthraquinone dye containing one or more phenyl or naphthyl groups, a more highly fused carbonyl-containing dye, a quinacridone, a perylene-3,4,9,10-tetracarboxylic acid diimide, an anthrapyrimidine, a pyrazoloanthrone, a diaminonaphthoquinone, a naphthazarine or a naphthalene-1,4,5,8-tetracarboxylic acid diimide.
    Type: Grant
    Filed: February 11, 1981
    Date of Patent: May 29, 1984
    Assignee: BASF Aktiengesellschaft
    Inventors: Manfred Patsch, Manfred Ruske