Benzene Ring Is Bonded Directly To Ring Nitrogen Of The Diazole Ring (e.g., 1-phenyl-3-methyl-5-pyrazolone; Antipyrine, Etc.) Patents (Class 548/371.1)
Abstract: This invention relates to a novel process of preparing selected 5-substituted pyrazoles useful as p38 kinase and COX-2 inhibitors.
Type:
Grant
Filed:
August 7, 2000
Date of Patent:
June 5, 2001
Assignee:
G. D. Searle & Co.
Inventors:
Matthew J. Graneto, Michael L. Vazquez, Susan J. Hartmann, Suzanne Metz, John J. Talley, David L. Brown, Richard M. Weier, Michael A. Stealey, Xiangdong Xu
Abstract: Novel herbicidal compounds, compositions containing them, and methods for their preparation and use in controlling weeds are disclosed. The novel herbicidal compounds are 3-(pyrazolylphenyl)propanoic acids and derivatives having the formula:
wherein X is H or halogen; Y is halogen, trihaloalkyl or cyano; Z and R are halogen; R1 is carboxyl or agriculturally acceptable salt thereof, cyano, alkoxycarbonyl, alkylthiocarbonyl, alkoxyalkoxycarbonyl, aminocarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, or alkylsulfonylaminocarbonyl; and R2 is hydrogen or lower alkyl.
Type:
Grant
Filed:
September 1, 1998
Date of Patent:
February 6, 2001
Assignee:
FMC Corporation
Inventors:
George Theodoridis, Scott D. Crawford, Lester L. Maravetz