Heavy Metal Or Aluminum Containing Patents (Class 548/402)
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Patent number: 7994312Abstract: A method of making a metalloporphyrin is carried out by reacting (i) a linear tetrapyrrole, said linear tetrapyrrole having a 19-acyl group and a 1-protecting group, with (ii) a metal salt under basic conditions to produce the metalloporphyrin. Products produced by such methods and intermediates useful for carrying out such methods are also described.Type: GrantFiled: February 11, 2008Date of Patent: August 9, 2011Assignee: North Carolina State UniversityInventors: Jonathan S. Lindsey, Dilek Dogutan Kiper
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Patent number: 7989580Abstract: Metal complexes of formula I and IA and polymers derived from the complexes are useful in optoelectronic devices wherein M is Ir, Co or Rh; is a cyclometallated ligand; R1 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, or substituted arylalkyl; R2 is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl; and at least one of R1 and R2 is other than hydrogen; R1a is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, or substituted arylalkyl; R2a is hydrogen, alkyl, substituted alkyl, aryl, substituted aryl, arylalkyl, substituted arylalkyl; and at least one of R1a and R2a is substituted alkyl, substituted aryl, substituted arylalkyl, and at least one substitutent of the substituted alkyl, substituted aryl, or substituted arylalkyl is a polymerizable group.Type: GrantFiled: October 29, 2008Date of Patent: August 2, 2011Assignee: General Electric CompanyInventors: Kyle Erik Litz, Kelly Scott Chichak, Donald Wayne Whisenhunt, Jr.
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Patent number: 7982064Abstract: The present disclosure relates to a method for preparing an ortho-substituted aminoferrocene comprising reacting an aminoferrocene with a Lewis acid and a lithiating reagent in the presence of an electrophile to form the ortho-substituted aminoferrocene.Type: GrantFiled: November 24, 2009Date of Patent: July 19, 2011Assignee: Brock UniversityInventor: Costa Metallinos
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Publication number: 20110172437Abstract: Advantageous methods for synthesis of fluorinated phthalocyanines are provided. Typical implementation involves a reaction mixture that includes perfluoro compound that is reacted for a reaction period sufficient to yield a fluorinated phthalocyanine of formula F64PcM, wherein “Pc” is any phthalocyanine macrocycle and “M” is hydrogen. Novel fluorinated phthalocyanine molecules/compounds are also provided herein, including specifically compounds that include fluorinated phthalocyanines wherein “M” is Cu or V?O. The fluorinated phthalocyanines have wide ranging applications, e.g., corrosion-related applications, coating-related applications, catalysis, and the production of optical and electronic materials.Type: ApplicationFiled: April 1, 2009Publication date: July 14, 2011Applicant: NEW JERSEY INSTITUTE OF TECHNOLOGYInventors: Sergiu M. Gorun, Robert Gerdes, Olga Gerdes, Lukasz Lapok
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Publication number: 20110171678Abstract: Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.Type: ApplicationFiled: October 18, 2010Publication date: July 14, 2011Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Wai-Yee Leung, Ching-Ying Cheung, Stephen Yue
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Publication number: 20110166349Abstract: Methods are provided for the catalytic hydroamination of compounds having an alkyne or allene functional group, in which the compound is contacted with ammonia or an amine in the presence of a catalytic amount of a gold complex under conditions sufficient for hydroamination to occur.Type: ApplicationFiled: May 8, 2009Publication date: July 7, 2011Applicant: The Regents of the University of CaliforniaInventors: Guy Bertrand, Vincent Lavallo, Guido D. Frey, Bruno Donnadieu, Michele Soleil-Havoup
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Publication number: 20110155996Abstract: Bistable carbazole compounds of formula (I) are described, wherein M is Fe, Co, Ru or Os, preferably Fe, useful as basic functional units for computing systems based on the QCA (Quantum Cellular Automata) paradigm; a process for their preparation is also described.Type: ApplicationFiled: March 9, 2011Publication date: June 30, 2011Applicant: STMicroelectronics S.R.L.Inventors: Pier Giorgio Cozzi, Luca Zoli, Alessandro Paolo Bramanti
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Patent number: 7964719Abstract: An inkjet ink for use in netpage, Hyperlabel and other applications. The ink includes an IR-absorbing dye of formula (I): wherein M is Ga(A1); A1 is an axial ligand selected from —OH, halogen, —OR3, —OC(O)R4, a hydrophilic ligand and/or a ligand suitable for reducing cofacial interactions; R1 and R2 may be the same or different and are selected from hydrogen or C1-12 alkoxy; R3 is selected from C1-12 alkyl, C5-12 aryl, C5-12 arylalkyl or Si(Rx)(Ry)(Rz); R4 is selected from C1-12 alkyl, C5-12 aryl or C5-12 arylalkyl; Rx, Ry and Rz may be the same or different and are selected from C1-12 alkyl, C5-12 aryl, C5-12 arylalkyl, C1-12 alkoxy, C5-12 aryloxy or C5-12 arylalkoxy; W is a hydrophilic group, each W group being independently selected from a substituent including a sulfonic acid group (including salts thereof), or a substituent comprising a sulfonamide group; n1 is 0, 1, 2 or 3; n2 is 0, 1, 2 or 3; n3 is 0, 1, 2 or 3; n4 is 0, 1, 2 or 3; and at least one of n1, n2, n3 or n4 is greater than 0.Type: GrantFiled: October 20, 2006Date of Patent: June 21, 2011Assignee: Silverbrook Research Pty LtdInventors: Simone Charlotte Vonwiller, Scott Matthew Starling, Damon Donald Ridley, Lachlan Everett Hall, Simon Fielder, Sutharsiny Indusegaram, Kia Silverbrook, Paul Lapstun
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Patent number: 7964746Abstract: Copper precursors useful for depositing copper or copper-containing films on substrates, e.g., microelectronic device substrates or other surfaces. The precursors includes copper compounds of various classes, including copper borohydrides, copper compounds with cyclopentadienyl-type ligands, copper compounds with cyclopentadienyl-type and isocyanide ligands, and stabilized copper hydrides. The precursors can be utilized in solid or liquid forms that are volatilized to form precursor vapor for contacting with the substrate, to form deposited copper by techniques such as chemical vapor deposition (CVD), atomic layer deposition (ALD) or rapid vapor deposition (digital CVD).Type: GrantFiled: March 30, 2008Date of Patent: June 21, 2011Assignee: Advanced Technology Materials, Inc.Inventors: Tianniu Chen, Chongying Xu, Thomas H. Baum, Bryan C. Hendrix, Jeffrey F. Roeder, Juan E. Dominguez, Adrien R. Lavoie, Harsono S. Simka
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Publication number: 20110144351Abstract: The present invention relates to 2,2?-di-substituted dipyrrins. The invention also relates to methods for the preparation of 2,2?-disubstituted dipyrrins, and to the use of 2,2?-disubstituted dipyrrins in, for example, sensing, imaging and laser applications.Type: ApplicationFiled: October 12, 2010Publication date: June 16, 2011Inventors: Mikhail Filatov, Andrei Cheprakov, Sergei A. Vinogradov, Artem Y. Lebedev
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Patent number: 7960565Abstract: This invention relates to organometallic compounds represented by the formula LML? wherein M is a metal or metalloid, L is a substituted or unsubstituted cyclopentadienyl group or cyclopentadienyl-like group, a substituted or unsubstituted pentadienyl group or pentadienyl-like group, or a substituted or unsubstituted pyrrolyl group or pyrrolyl-like group, and L? is a substituted or unsubstituted pyrrolyl group or pyrrolyl-like group, a process for producing the organometallic compounds, and a method for producing a film or coating from the organometallic compounds. The organometallic compounds are useful in semiconductor applications as chemical vapor or atomic layer deposition precursors for film depositions.Type: GrantFiled: September 23, 2009Date of Patent: June 14, 2011Assignee: Praxair Technology, Inc.Inventor: Scott Houston Meiere
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Publication number: 20110137025Abstract: The disclosure provides metal organic frameworks useful for sensing, gas sorption, microelectronics and switches.Type: ApplicationFiled: June 5, 2009Publication date: June 9, 2011Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Omar M Yaghi, Qiaowei Li, Ognjen S Miljanic, Wenya Zhang, James Frasere Stoddart
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Publication number: 20110135838Abstract: The present invention is related to a family of liquid group 4 precursors represented by the formula: (pyr*)M(OR1)(OR2)(OR3) wherein pyr* is an alkyl substituted pyrrolyl, wherein M is group 4 metals include Ti, Zr, and Hf; wherein R1-3 can be same or different and selected from group consisting of linear or branched C1-6 alkyls; preferably C1-3 alkyls; R4 is selected from the group consisting of C1-6 alkyls, preferably branched C3-5 alkyls substituted at 2, 5 positions to prevent the pyrrolyl coordinated to the metal center in ?1 fashion; n=2, 3, 4. Most preferably the invention is directed to (2,5-di-tert-butylpyrrolyl)(tris(ethoxy)titanium, (2,5-di-tert-amylpyrrolyl)(tris(ethoxy)titanium, and (2,5-di-tert-amylpyrrolyl)(tris(iso-propoxy)titanium. The invention is also directed to (cyclopentadienyl)(2,5-di-methylpyrrolyl)(bis(ethoxy))titanium. Deposition methods using these compounds are also contemplated.Type: ApplicationFiled: November 19, 2010Publication date: June 9, 2011Applicant: AIR PRODUCTS AND CHEMICALS, INC.Inventors: Xinjian Lei, John Anthony Thomas Norman, Daniel P. Spence
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Patent number: 7955716Abstract: It is an object of the present invention to provide a phosphorescence-emitting material that emits light in a wide visible light range from blue to red and has excellent color purity and reliability, etc. The present invention relates to a metal coordination compound represented by any one of Formulae (1) to (6), B: >NR, >O, >S, >C?O, >SO2, >CR2 (in the formulae, M is Ir, Rh, Ru, Os, Pd, or Pt, and n is 2 or 3; when M is Ir, Rh, Ru, or Os and n is 2, another bidentate ligand further bonds to M; ring A is a cyclic compound containing a nitrogen atom bonded to M.Type: GrantFiled: June 9, 2004Date of Patent: June 7, 2011Assignee: Hitachi Chemical Co., Ltd.Inventors: Satoyuki Nomura, Yoshii Morishita, Yoshihiro Tsuda
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Publication number: 20110118438Abstract: Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.Type: ApplicationFiled: January 24, 2011Publication date: May 19, 2011Inventor: Giuseppe CAPUTO
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Publication number: 20110118475Abstract: The current application relates to a metal catalyst of formula (I): M[ADC][X]n, wherein M is a metal, ADC is a chiral acyclic diaminocarbene ligand, and X is a neutral or anionic ligand. The ADC ligand is prepared from the corresponding chiral formamidium salt precursor. The metal catalyst is used for asymmetric organic synthesis reactions such as hydrosilations, hydrogenations, conjugate additions, and cross-couplings.Type: ApplicationFiled: July 7, 2009Publication date: May 19, 2011Inventors: Avinash N. Thadani, Rukundo Ntaganda, Mira M. Beshai
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Publication number: 20110112296Abstract: Organic light emitting devices are described wherein the emissive layer comprises a host material containing an emissive molecule, which molecule is adapted to luminesce when a voltage is applied across the heterostructure, and the emissive molecule is selected from the group of phosphorescent organometallic complexes, including cyclometallated platinum, iridium and osmium complexes. The organic light emitting devices optionally contain an exciton blocking layer. Furthermore, improved electroluminescent efficiency in organic light emitting devices is obtained with an emitter layer comprising organometallic complexes of transition metals of formula L2MX, wherein L and X are distinct bidentate ligands. Compounds of this formula can be synthesized more facilely than in previous approaches and synthetic options allow insertion of fluorescent molecules into a phosphorescent complex, ligands to fine tune the color of emission, and ligands to trap carriers.Type: ApplicationFiled: January 19, 2011Publication date: May 12, 2011Inventors: Mark E. THOMPSON, Peter Djurovic H, Sergey Lamansky, Drew Murphy, Raymond Kwong, Feras Abdel-Razzaq, Stephen R. Forrest, Marc A. Baldo, Paul E. Burrows
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Publication number: 20110111162Abstract: A novel indolium compound of general formula (I) and an optical recording material containing the indolium compound. In formula (I), ring A is a benzene ring, etc.; ring B is a 5- or 6-membered heterocyclic ring; R1 is a group of general formula (II), etc.; R2 is an organic group having 1 to 30 carbon atoms, etc.; Y1 is an alkyl group having 1 to 10 carbon atoms, etc.; Z1 and Z2 are each, e.g., an alkyl group having 1 to 8 carbon atoms optionally substituted with a halogen atom and optionally interrupted by —O—, etc.; a is an integer of 0 to 6; b is an integer of 0 to 5; Anq? is a q-valent anion; q is 1 or 2; and p is a number necessary to neutralize an electric charge.Type: ApplicationFiled: September 26, 2008Publication date: May 12, 2011Applicant: ADEKA CORPORATIONInventors: Toru Yano, Yohei Aoyama
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Publication number: 20110112304Abstract: This invention relates to a carbene complex of metal salt represented by the formula: [T?M(R)c]n wherein, R is a monoanionic group; c is 1 or 2; M is a Li or Mg; T is a cyclic carbene ligand; and n is selected from the group of integers comprising 1 to 24 wherein the complex has 50% or less decomposition when stored in 0.01 molar benzene at 23° C. for a period of 1 hour. This invention also relates to transition-metal-carbene complexes prepared from such carbene complexes of metal salts, where the transition-metal-carbene complex is represented by the formula: [M*(T)(L0)q(L1?)s(L2?)t]g, where M* is a transition metal from Group 6, 7, 8, 9, 10, 11 or 12, T is a cyclic carbene ligand, L° is a neutral ligand, L1? is a monoanionic ligand, L2? is a dianionic ligand, q is 0, 1, 2, 3 or 4, s is 0, 1, 2, 3, or 4, t is 0, 1, 2, 3, or 4, g is the overall charge of the molecule. The transition-metal-carbene complexes may be used for synthesis reactions, including metathesis of olefins.Type: ApplicationFiled: November 3, 2010Publication date: May 12, 2011Inventors: John R. Hagadorn, Matthew W. Holtcamp, Matthew S. Bedoya, Renuka N. Ganesh
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Publication number: 20110104103Abstract: The present invention relates to a cell-targeting complex comprising a targeting moiety and a deliverable compound, wherein said targeting moiety and said deliverable compound are joined by means of a (transition) metal ion complex having at least a first reactive moiety for forming a coordination bond with a reactive site of said targeting moiety and having at least a second reactive moiety for forming a coordination bond with a reactive site of said deliverable compound, and wherein said deliverable compound is a therapeutic compound.Type: ApplicationFiled: July 20, 2006Publication date: May 5, 2011Applicant: KREATECH BIOTECHNOLOGY B.V.Inventors: Robert Jochem Heetebrij, Robbert Jan Kok, Eduard Gerhard Talman, Klaas Poelstra, Grietje Molema
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Publication number: 20110098263Abstract: A method for treatment of cancer by inhibiting the activity of histone deacetylase, comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of a gold(III) complex having the structural formula of or a pharmaceutically acceptable salt thereof, wherein: —R is selected from the group consisting of —OH, —CH2OH, C2H4OH, —C3H6OH or —C4H8OH; and X is independently a pharmaceutically acceptable counter-ion.Type: ApplicationFiled: October 27, 2010Publication date: April 28, 2011Inventors: Chi Ming Che, Yu Wang, Raymond Wai Yin Sun, Kim Hei-Man Chow
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Publication number: 20110098262Abstract: Transition metal complexes of amphiphilic corroles, optical isomers and pharmaceutically acceptable salts thereof are useful for neuroprotection and neurorescue, particularly for treatment of diabetes and neurodegenerative diseases. The amphiphilic corrole is preferably a 5,10,15-tris-aryl- or 5,10,15-tris-CF3-corrole, and said transition metal complex more preferably has the formula I defined in the specification. Also provided are propargyl-containing corroles carrying one or more radicals substituted by a propargylamino group or one or more nitrogen-containing heteroaryl radicals substituted by propargyl at the ring N atom.Type: ApplicationFiled: February 1, 2009Publication date: April 28, 2011Inventors: Moussa B.H. Yondim, Silvia Mandel, Tamar Amit, Orit Bar-Am, Lana Kupershmidt, Zeev Gross, Atif Mahammed, Irena Saltsman, Zoya Okun
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Patent number: 7932397Abstract: The present invention provides methods for the synthesis of catalysts and precursors thereof. Methods of the invention may comprise combining a catalyst precursor and at least one ligand to generate a catalytically active species, often under mild conditions and in high yields. In some cases, a wide variety of catalysts may be synthesized from a single catalyst precursor. Methods of the invention may also include the preparation of catalysts which, under reaction conditions known in the art, may have been difficult or impossible to prepare and/or isolate due to, for example, steric crowding at the metal center. The present invention also provides catalyst compositions, and precursors thereof, which may be useful in various chemical reactions including olefin metathesis. In some cases, methods of the invention may reduce the number of synthetic and purification steps required to produce catalysts and/or other reaction products, as well as reducing time, cost, and waste production.Type: GrantFiled: November 22, 2006Date of Patent: April 26, 2011Assignee: Massachusetts Institute of TechnologyInventors: Adam S. Hock, Richard R. Schrock
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Publication number: 20110089818Abstract: Monomeric metal complexes having desirable luminescence properties are provided. In one embodiment, a monomeric metal compound is represented by the formula (ArN)M(L)x, where ArN is an arylamido ligand, and M may be any metal capable of exhibiting luminescent properties, for example, a d10 metal. L may be a tertiary phosphine.Type: ApplicationFiled: October 16, 2009Publication date: April 21, 2011Inventors: Jonas C. Peters, Kenneth J. Lotito
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Publication number: 20110046392Abstract: The invention provides an oxo-titanylphthalocyanine crystal which is stable, is superior in dispersibility in a photoreceptive layer and efficiently contributes to improvements in sensitivity and charge retention rate of an electrophotographic photoreceptor when it is used as a charge generating agent, a method for producing the oxo-titanylphthalocyanine crystal, and an electrophotographic photoreceptor.Type: ApplicationFiled: October 1, 2010Publication date: February 24, 2011Inventors: Daisuke Kuboshima, Jun Azuma, Yoshio Inagaki, Junichiro Otsubo, Keiji Maruo
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Publication number: 20110038803Abstract: A fluorescent probe which specifically and efficiently traps nitrogen monoxide, zinc ion etc. to emit fluorescence is provided. A compound represented by the following general formula (I): [wherein R1 and R2 represent hydrogen atom, or a group represented by the following formula (A): (wherein X1 to X4 represent hydrogen atom, an alkyl group, or a protective group for amino group, and m and n represent 0 or 1); R3 and R4 represent hydrogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; R5 to R12 represent hydrogen atom, sulfo group, phospho group, a halogen atom, or a C1-6 alkyl group; R13 and R14 represent a C1-18 alkyl group; Z1 represents oxygen atom, sulfur atom, or —N(R15)— (wherein R15 represents hydrogen atom, or a C1-6 alkyl group); Y1 and Y2 represent —C(?O)—, —C(?S)—, or —C(R16)(R17) (wherein R16 and R17 represent a C1-6 alkyl group); and M? represents a counter ion in a number required for neutralizing the charge].Type: ApplicationFiled: October 25, 2010Publication date: February 17, 2011Inventors: Tetsuo NAGANO, Eita SASAKI, Hirotatsu KOJIMA, Tomoya HIRANO, Kazuya KIKUCHI
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Publication number: 20110028716Abstract: The present invention relates to a dye for a dye-sensitised solar cell. The dye according to the present invention has a high degree of light absorbency and can improve the photoelectric current conversion efficiency when employed in a light-absorbing layer for a solar cell.Type: ApplicationFiled: February 5, 2009Publication date: February 3, 2011Applicant: SOLARSYS CO., LTD.Inventors: Kwang-Yol Kay, Kang-Jin Kim, Jong-Hyung Kim, Young-Jin Kwon
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Publication number: 20110015401Abstract: One aspect of the invention relates to a metal-catalyzed conversion of aryl halides and sulfonates to the corresponding aryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of heteroaryl halides and sulfonates to the corresponding heteroaryl fluorides. Another aspect of the invention relates to a metal-catalyzed conversion of vinyl halides and sulfonates to the corresponding vinyl fluorides. In certain embodiments, simple fluoride sources, such as AgF and CsF, are used. In certain embodiments, the transformations tolerate a wide range of functional groups, allowing for introduction of fluorine atoms into highly functionalized organic molecules.Type: ApplicationFiled: July 13, 2010Publication date: January 20, 2011Applicant: Massachusetts Institute of TechnologyInventors: Stephen L. Buchwald, Donald Allen Watson, Mingjuan Su, Georgiy Teverovskiy
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Publication number: 20110006670Abstract: Disclosed is an organic electroluminescence element comprising an anode, a cathode and a plurality of organic compound layers between the anode and the cathode, provided that one of the organic compound layers is a light emitting layer containing a phosphorescence emitting compound, wherein at least one of the organic compound layers contains a compound represented by Formula (1), wherein, X represents O or S; Y1 to Y3 each represents a hydrogen atom, a substituent or a group represented by Formula (A) disclosed in the specification, provided that at least two of Y1 to Y3 are groups represented by Formula (A), not all of Y1 to Y3 are the same group, and at least one of the groups represented by Formula (A) has Ar of a carbazolyl group, or an azacarbazolyl group containing 2 to 5 nitrogen atoms.Type: ApplicationFiled: April 1, 2010Publication date: January 13, 2011Applicant: KONICA MINOLTA HOLDINGS, INC.Inventors: Rie KATAKURA, Shuichi SUGITA, Eisaku KATOH, Motoaki SUGINO, Rie FUJISAWA
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Publication number: 20100330077Abstract: Compounds of general formula (I) wherein R1 is halo or cyano; R2 is C1-C4 alkyl; and R3 is phenyl substituted with one or more substituents chosen from C1-C6 alkyl, halo or —SO2(C1-C6 alkyl); or a pharmaceutically acceptable salt, hydrate, solvate, complex or prodrug thereof; are useful in the treatment of diseases and conditions mediated by the action of PGD2 at the CRTH2 receptor.Type: ApplicationFiled: March 10, 2006Publication date: December 30, 2010Applicant: OXAGEN LIMITEDInventors: Richard Edward Armer, Edward Andrew Boyd, Philip Andrew Hay
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Publication number: 20100304074Abstract: A novel indolium compound of general formula (I) and an optical recording material containing the indolium compound. In general formula (I), ring A is a benzene ring, etc.; R1 is a group of general formula (II), etc.; R2 is a C1-C30 organic group, etc.; Y1 is a C1-C10 alkyl group, etc.; Z1 is, e.g., a C1-C8 alkyl group optionally substituted with a halogen group and optionally interrupted by —O—, etc.; Z2 is, e.g., a C1-C8 alkyl group optionally substituted with a halogen group and optionally interrupted by —O—, etc.; a is an integer of 0 to 6; b is an integer of 0 to 5; Anq- is a q-valent anion; q is 1 or 2; and p is a number necessary to neutralize an electric charge.Type: ApplicationFiled: September 26, 2008Publication date: December 2, 2010Applicant: ADEKA CORPORATIONInventors: Toru Yano, Yohei Aoyama
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Publication number: 20100305335Abstract: Metallocorrole complexes of third row transition metals may be used as therapeutic agents, catalysts, components of oxygen detectors, and components of light emitting diodes. In particular, metallocorrole complexes of third row transition metals may be used as improved photosenitizers in photodynamic therapy; as improved catalysts in aziridination, epoxidation, and water splitting reactions; as improved in vivo imaging agents; and as improved components in the emissive layer of OLEDs. Due to their strongly sigma-donating nature, corroles are able to stabilize third row transition metals in high oxidation states. Third row transition metals are significantly more electropositive than their first and second row counterparts and may therefore act as improved catalysts.Type: ApplicationFiled: May 24, 2010Publication date: December 2, 2010Inventors: Joshua H. Palmer, Zeev Gross, Harry B. Gray
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Publication number: 20100286407Abstract: A naphthalocyanine compound of formula (I): wherein R111, R121, R131 and R141 represent a group of formula (II); R112, R122, R132 and R142 represent a substituent; M1 represents two hydrogen atoms, two monovalent metal atoms, etc.; n112, n122, n132 and n142 are 0 to 4; R211 represents H, an aliphatic group, etc.; R212 and R213 represent an aliphatic group, an aromatic group, etc.; L211 represents a divalent group consisting of a carbon chain having at least 2 carbon atoms.Type: ApplicationFiled: December 22, 2006Publication date: November 11, 2010Inventors: Keizou Kimura, Katsuyoshi Yamagawa
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Patent number: 7825249Abstract: The invention relates to novel metal complexes. Said compounds can be used as functional material in a series of different applications which in the broadest sense can be attributed to the electronics industry. The inventive compounds are described by the formula (1) and by compounds (1) to (52).Type: GrantFiled: May 14, 2005Date of Patent: November 2, 2010Assignee: Merck Patent GmbHInventors: Philipp Stössel, Esther Breuning
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Patent number: 7825259Abstract: The reaction of N-alkylimidazol with alkyl sulfonates, at room temperature, favors the production of 1,3-dialkylimidazolium alkane-sulfonates as crystalline solids at high yields. The alkane-sulfonate anions may be easily substituted by a series of other anions [BF4, PF6, PF3(CF2CF3)3, CF3SO3 and (CF3SO2)2N] through simple anion, salt, or acid reactions in water at room temperature. The extraction with dichloromethane, filtration, and evaporation of the solvent, allows the production of the desired ionic liquids at a yield of 80-95%. The purity of these ionic liquids (in some cases >99.4%) is performed using the intensity of 13C satellite signals from the magnetic resonance spectrums of the N-methyl imidazolium group as an internal standard.Type: GrantFiled: April 25, 2007Date of Patent: November 2, 2010Assignee: Petroleo Brasileiro S.A. - PetrobrasInventors: Cláudia Cristiana Cassol, Bauer Costa Ferrera, Gunter Ebeling, Jairton Dupont
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Publication number: 20100270915Abstract: The present invention discloses a phosphor material for organic optoelectronic devices. The phosphor is a complex comprising a metal (Ir or Pt) and an aryl-modified beta-diketone ligand. The complexes of this invention are useful to function as an emitter in the emissive layer of an organic light emitting diode, even as the complex is the main component of this layer.Type: ApplicationFiled: April 23, 2010Publication date: October 28, 2010Applicant: National Tsing Hua UniversityInventors: Chien-Hong Cheng, Fang-ly Wu, Chin-Hsien Chen
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Patent number: 7816531Abstract: The invention relates to novel metal complexes. Said compounds can be used as functional materials in a series of different types of applications that can be attributed in the broadest sense to the electronics industry The inventive compounds are defined by formula (1).Type: GrantFiled: July 14, 2005Date of Patent: October 19, 2010Assignee: Merck Patent GmbHInventors: Philipp Stössel, Esther Breuning
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Patent number: 7799926Abstract: The present invention relates to novel polar fluorescent and quenchers dyes, and minor groove binder with enhanced polarity. The present invention further relates to methods of preparing oligonucleotide probes labeled with polar arsonate dyes under the condition of automated synthesis and method of using such probes.Type: GrantFiled: March 9, 2006Date of Patent: September 21, 2010Assignee: CepheidInventor: Alexander A Gall
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Patent number: 7799526Abstract: A phosphoprotein detection reagent that selectively binds phosphoamino acids. Methods of generating and employing the reagent are also provided, as are methods of detecting modulation of protein phosphorylation are disclosed. Methods of detecting a change in state of a cell are also disclosed. Additionally, a kit for the detection of phosphoproteins is also disclosed.Type: GrantFiled: November 21, 2003Date of Patent: September 21, 2010Assignee: The University of North Carolina at Chapel HillInventor: Alan Howe
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Publication number: 20100204474Abstract: A cyanine compound represented by the general formula (I), (VI) or (VII): wherein ring-A1 is an optionally substituted benzene or naphthalene ring; B is a group represented by the general formula (II) or (III); R1 is a hydrogen atom, a halogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, or an aryl group having 6 to 30 carbon atoms; R2 is a substituent represented by the general formula (IV); and Y1 is a hydrogen atom, an organic group having 1 to 30 carbon atoms, or a substituent represented by the general formula (IV): wherein ring-A2 is the same as the ring-A1 in the general formula (I); Y4 and Y5 each are independently the same as Y1 in the general formula (I); X2 is the same as X1 in the general formula (I); R10 is the same as R1 in the general formula (I); R11 is the same as R2 in the general formula (I); R23 and R24 are the same as R21 and R22 in the formulas (II) and (III); n is an integer of 0 to 6; the polymethine chain may have a substType: ApplicationFiled: April 21, 2010Publication date: August 12, 2010Applicant: ADEKA CORPORATIONInventors: Yohei AOYAMA, Koichi SHIGENO
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Publication number: 20100190180Abstract: The subject invention concerns methods and materials for cancer screening using platinum complexes to detect a STAT protein biomarker. Platinum (IV) complexes interacting with STATs directly correlate with the STAT expression. In one embodiment, fluorescently-labeled and/or antibody-linked platinum (IV) complexes can be used to assess the STAT expression and define malignant potential. Other methods such as imaging (MRI, e.g.) can also be used to assess platinum-STAT interactions. The STAT protein can be, for example, STAT3.Type: ApplicationFiled: July 6, 2006Publication date: July 29, 2010Inventor: Heidi Kay
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Publication number: 20100173427Abstract: Methods, compositions and kits are disclosed directed at levetiracetam derivatives, immunogens, signal generating moieties, antibodies that bind levetiracetam and immunoassays for detection of levetiracetam.Type: ApplicationFiled: October 22, 2009Publication date: July 8, 2010Inventors: Johnny Jose Valdez, Byung Sook Moon, Ki Chung, Alejandro A. Orozco
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Patent number: 7741514Abstract: A catalyst of the invention includes an imide compound having a N-substituted cyclic imide skeleton represented by following Formula (I): wherein R is a hydroxyl-protecting group. Preferred R is a hydrolyzable protecting group. R may be a group obtained from an acid by eliminating an OH group therefrom. Such acids include, for example, carboxylic acids, sulfonic acids, carbonic acid, carbamic acid, sulfuric acid, nitric acid, phosphoric acids and boric acids. The catalyst may include the imide compound and a metallic compound in combination. In the presence of the catalyst, (A) a compound capable of forming a radical is allowed to react with (B) a radical scavenging compound and thereby yields an addition or substitution reaction product of the compound (A) and the compound (B) or a derivative thereof. This catalyst can produce an organic compound with a high selectivity in a high yield as a result of, for example, an addition or substitution reaction under mild conditions.Type: GrantFiled: August 15, 2006Date of Patent: June 22, 2010Assignee: Daicel Chemical Industries, Ltd.Inventors: Yasutaka Ishii, Tatsuya Nakano, Takahiro Iwahama, Naruhisa Hirai
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Publication number: 20100152153Abstract: Compositions comprising nitrosyl-cobinamide are provided. Also provided are methods for treating hypertension, which comprise administering therapeutically effective amounts of nitrosyl-cobinamide. Also provided are methods for producing nitrosyl-cobinamide.Type: ApplicationFiled: April 10, 2008Publication date: June 17, 2010Applicant: The Regents of The Univeristy of CaliforniaInventors: Gerry R. Boss, Vijay Sharma, Kate E. Broderick
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Publication number: 20100140593Abstract: A thin-film transistor has a semiconducting layer which comprises a halogen-coordinated metal phthalocyanine complex of Formula (I) or Formula (II): wherein M is a trivalent metal atom; each m represents the number of R substituents on the phenyl or naphthyl ring, and is independently an integer from 0 to 6; each R is independently selected from the group consisting of halogen, alkyl, substituted alkyl, alkoxy, substituted alkoxy, phenoxy, phenylthio, aryl, substituted aryl, heteroaryl, —CN, and —NO2; and X is a halogen atom.Type: ApplicationFiled: December 10, 2008Publication date: June 10, 2010Applicant: XEROX CORPORATIONInventors: Yiliang Wu, Ah-Mee Hor, Yuning Li, Ping Liu, Paul F. Smith
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Publication number: 20100137588Abstract: The present disclosure relates to a method for preparing an ortho-substituted aminoferrocene comprising reacting an aminoferrocene with a Lewis acid and a lithiating reagent in the presence of an electrophile to form the ortho-substituted aminoferrocene.Type: ApplicationFiled: November 24, 2009Publication date: June 3, 2010Applicant: BROCK UNIVERSITYInventor: Costa Metallinos
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Patent number: 7728149Abstract: A process produces a corresponding dicarboxylic acid by subjecting a cycloalkane to an oxidative cleavage reaction with oxygen in the presence of a catalyst in a liquid phase using a continuous reactor, in which a residence time ? (hr) satisfies the following condition: 0.1???50/c, wherein c is the proportion (% by weight) of the cycloalkane to the total weight of a charged liquid. The catalyst includes, for example, cobalt compounds, manganese compounds, and mixtures of these compounds, as well as imide compounds having at least one cyclic imide skeleton.Type: GrantFiled: January 14, 2003Date of Patent: June 1, 2010Assignee: Daicel Chemical Industries, Ltd.Inventors: Kiyokazu Murata, Hiroyuki Miura
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Publication number: 20100111981Abstract: A synthetic monodisperse hemozoin crystals preparation, compositions and methods of preparation thereof, are described. Also described are uses thereof, including use as an adjuvant, use in an immunogenic or vaccine composition, use for enhancing or inducing immunogenicity, and corresponding prevention or treatment of disease or infection.Type: ApplicationFiled: June 22, 2007Publication date: May 6, 2010Applicant: The Royal Institution for the Advancement of Learning/McGill UniversityInventors: David Scott Bohle, Martin Olivier
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Publication number: 20100113786Abstract: Disclosed is a method for highly efficiently obtaining an optically active alcohol from a carbonyl compound highly enantioselectively. Also disclosed is a ligand used in such a method. Specifically, an optically active alcohol is obtained by reacting a carbonyl compound and an organozinc compound by using a ligand (L) shown below.Type: ApplicationFiled: February 19, 2008Publication date: May 6, 2010Applicants: National University Corporation Nagoya University, SEKISUI MEDICAL CO., LTD.Inventors: Kazuaki Ishihara, Manabu Hatano, Takashi Miyamoto
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Patent number: 7709659Abstract: Tetraphosphorous ligands are combined with transition metal salts to form catalysts for use in hydroformylation, isomerization-hydroformylation, hydrocarboxylation, hydrocyan-ation, isomerization-formylation, hydroaminomethylation and similar related reactions.Type: GrantFiled: April 17, 2009Date of Patent: May 4, 2010Assignee: The Penn State Research FoundationInventors: Xumu Zhang, Yongjun Yan