Purification Or Recovery Patents (Class 564/437)
  • Patent number: 9162970
    Abstract: Methods and systems for purifying a crude aniline. The method can include contacting a crude aniline that can include aniline, water, and cyclohexanone with a cation exchange resin to produce a cyclohexanone-lean product that contains less cyclohexanone than the crude aniline. The cation exchange resin can be a solid, a semi-solid, or a combination thereof.
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: October 20, 2015
    Assignee: KELLOGG BROWN & ROOT LLC
    Inventors: Theodor Wilks, Eric Wing-Tak Wong, Matthew R. Ulrich
  • Publication number: 20150094493
    Abstract: The present invention relates to a method for treating a substance mixture comprising an aromatic amine, wherein the aromatic amine is aniline or 2,4-diaminotoluene, preferably aniline. The substance mixture comprises an aromatic amine and compounds having a higher boiling point than the aromatic amine. The method for treating the substance mixture requires I) separating the first substance mixture by means of distillation in a first distillation unit (110, 1130), to at least partially remove some of the aromatic amine in the process, and to obtain a first bottom product which is removed from the first distillation unit (110, 1130). After removal from the first distillation unit (110, 1130), the bottom product is diluted with a condensed top product from a distillation unit that is different from the first distillation unit and/or with a composition that comprises methanol.
    Type: Application
    Filed: April 29, 2013
    Publication date: April 2, 2015
    Inventors: Michael Merkel, Thomas Knauf, Cliff Andre Peters, Thorsten Schmidt
  • Patent number: 8981156
    Abstract: This invention relates to methods, which provide access to [F-18]fluoropegylated (aryl/heteroaryl vinyl)-phenyl methyl amine derivatives.
    Type: Grant
    Filed: May 30, 2011
    Date of Patent: March 17, 2015
    Assignee: Piramal Imaging SA
    Inventors: Mathias Berndt, Matthias Friebe, Christina Hultsch, Fabrice Samson, Marianne Patt, Andreas Schildan, Christoph Smuda
  • Patent number: 8697913
    Abstract: According to the present invention, a chemical installation is provided. The chemical installation comprises A first unit for providing a first aqueous waste stream comprising nitrobenzene; At least a second unit for providing a second aqueous waste stream comprising aniline. The chemical installation comprises an aniline cleaning apparatus for removing nitrobenzene from aniline, and further comprising a stripping column for stripping aniline from an aqueous stream. The first and second aqueous waste stream are provided to the stripping column, stripping aniline and nitrobenzene from the first and the aqueous waste stream, and the stripped aniline and nitrobenzene is provided to the aniline cleaning apparatus.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: April 15, 2014
    Assignee: Huntsman International LLC
    Inventors: Arend-Jan Zeeuw, Mark Geoffrey Bent
  • Patent number: 8686188
    Abstract: A method for refining an organic composition containing 4-aminodiphenylamine, aniline, azobenzene, and phenazine, having the steps of feeding the organic composition to a first rectification column, producing a first effluent composition containing aniline, azobenzene, phenazine, and a small amount of 4-aminodiphenylamine at the top of the first rectification column and a second effluent composition containing crude 4-aminodiphenylamine at the bottom of the first rectification column, feeding the second effluent composition to a second rectification column, and producing a 4-aminodiphenylamine composition at the top of the second rectification column and a residual composition at the bottom of the second rectification column.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: April 1, 2014
    Assignee: Jiangsu Sinorgchem Technology Co., Ltd.
    Inventors: Xiaogen Feng, Nongyue Wang, Xiaohui Mao, Ruibiao Yu, Qianwen Cheng, Renping Jiao
  • Patent number: 8658828
    Abstract: The recovery of toluene diamine from tar waste residues discharged from the synthesis process of toluene diisocyanate comprising steps of: a) grinding the tar waste residues into particles; b) dispersing the particles of tar waste residues into a phase transfer catalyst, alkali and water to obtain a slurry, said phase transfer catalyst being selected from the group consisting of higher alcohols, polyols, polyether compounds and combinations thereof having a boiling point ranging from 120 to 280° C.; c) under the protection of a protective gas, subjecting the slurry to a hydrolysis reaction at a temperature of 120-180° C. under a meter-measured pressure of 0-0.95 MPa to produce toluene diamine; and d) recovering toluene diamine from the hydrolysis reaction solution. The present invention achieves highly efficient recovery of toluene diamine (the recovery rate of TDA is up to 60%) under mild conditions such as 120-180° C. and 0-0.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: February 25, 2014
    Assignee: Cangzhou Fengyuan Environmental Protection Science and Technology Co., Ltd.
    Inventor: Deshui Su
  • Publication number: 20130324763
    Abstract: A process for the synthesis of chiral propargylic alcohols.
    Type: Application
    Filed: October 14, 2011
    Publication date: December 5, 2013
    Applicant: LONZA LTD
    Inventors: Meinrad Brenner, Erick M. Carreira, Nicka Chinkov, Miriam Lorenzi, Aleksander Warm, Lothar Zimmermann
  • Patent number: 8546615
    Abstract: The present invention relates to solid racemic dapoxetine, solid dapoxetine S(+)enantiomer, processes for their preparation and their use in the pharmaceutically active compound dapoxetine acid addition salt, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: October 1, 2013
    Assignee: Symed Labs Limited
    Inventors: Dodda Mohan Rao, Pingili Krishnareddy, Aadepu Jithender
  • Publication number: 20130172620
    Abstract: This invention relates to methods, which provide access to [F-18]fluoropegylated (aryl/heteroaryl vinyl)-phenyl methyl amine derivatives.
    Type: Application
    Filed: May 30, 2011
    Publication date: July 4, 2013
    Applicant: PIRAMAL IMAGING SA
    Inventors: Mathias Berndt, Matthias Friebe, Christina Hultsch, Fabrice Samson, Marianne Patt, Andreas Schildan, Christoph Smuda
  • Publication number: 20120289631
    Abstract: Disclosed is aromatic diamine with high purity obtained by efficiently removing impurities and preventing oxidation, and a method for manufacturing the same; and aramid fiber with improved discoloration resistance realized by preventing deterioration in quality even for a long-period exposure to the external environments of sunlight, atmosphere, and moisture, and a method for manufacturing the same.
    Type: Application
    Filed: December 29, 2010
    Publication date: November 15, 2012
    Inventors: Hyojin Lee, In Sik Han
  • Publication number: 20120083626
    Abstract: The invention relates to a process for obtaining at least one aromatic amine from a liquid mixture comprising water and the at least one aromatic amine by extracting with at least one nitroaromatic in an extraction column (1) to form an essentially water-comprising raffinate stream and an extract stream comprising the at least one nitroaromatic and the aromatic amine. The extraction column (1) is divided by a dividing wall (3) into two regions (5, 7), and, in the case of an amount of liquid for separation which is less than a minimum cross sectional loading of the entire extraction column (1), the liquid mixture to be separated is fed only to one of the regions (5, 7) of the extraction column (1) divided by the dividing wall (3). The invention further relates to a process for preparing an aromatic amine and to an apparatus for separating a liquid mixture comprising water and at least one aromatic amine by extracting with at least one nitroaromatic, comprising an extraction column (1).
    Type: Application
    Filed: May 6, 2010
    Publication date: April 5, 2012
    Applicant: BASF SE
    Inventors: Tilmann Steinmetz, Michael Nilles, Lucia Koenigsmann, Andreas Heussler, Nikolaus Zafred
  • Patent number: 8110073
    Abstract: Aromatic amines are produced by catalytic hydrogenation of aromatic nitro compounds. The reaction mixture generated by this hydrogenation is then worked up by distillation in a manner which makes it possible to substantially free the amine of water with increased energy efficiency. Water free of amine and low boilers and the low boiling materials are also obtained.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: February 7, 2012
    Assignee: Bayer MaterialScience AG
    Inventors: Bernd Pennemann, Bill Brady, Rainer Buse
  • Publication number: 20110305618
    Abstract: The invention pertains to a method for eluting a radionuclide-label or a radionuclide-labeled compound using a solid phase extraction resin, to a device for performing such a method, and to a computer program for controlling such a device.
    Type: Application
    Filed: December 12, 2009
    Publication date: December 15, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith Graham, Axel Rother, Dominic Franck
  • Patent number: 8071813
    Abstract: A method in one embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having a fluoride anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of about 90° C. or less during the contacting. A method in another embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having an acetate or formate anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of less than about 90° C. during the contacting.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: December 6, 2011
    Assignee: Lawrence Livermore National Security, LLC
    Inventors: Philip Pagoria, Amitesh Maiti, Alexander Gash, Thomas Yong Han, Christine Orme, Laurence Fried
  • Patent number: 7989662
    Abstract: A process for preparing 4-aminodiphenylamine having the steps of reacting nitrobenzene and aniline in the presence of a complex base catalyst, hydrogenating the reaction mixture with hydrogen, a powdery composite catalyst, and a hydrogenation solvent; separating, recovering, and reusing the complex base catalyst and the powdery composite catalyst from the reaction mixture; separating, recovering, and reusing aniline, and optionally water, from the reaction mixture; refining the reaction mixture to obtain 4-aminodiphenylamine. The complex base catalyst comprises tetraalkyl ammonium hydroxide, and tetraalkyl ammonium salt.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: August 2, 2011
    Assignee: Jiangsu Sinorgchem Technology Co., Ltd.
    Inventors: Xiaogen Feng, Nongyue Wang, Xiaohui Mao, Ruibiao Yu, Qianwen Cheng
  • Patent number: 7928265
    Abstract: Method of preparation of antioxidant composition on the basis of diphenylamine by catalytic alkylation of diphenylamine by an threefold excess of diisobutylene with regard to diphenylamine in the presence of an alkylation catalyst t in an amount of 5 to 30% by weight, as referred to diphenylamine, at a temperature of 140 to 160° C. Water contained in the catalyst, is removed and subsequently diphenylamine is left to complete the reaction with diisobutylene and after the reaction is finished, the reaction mixture is separated from the catalyst, unreacted diisobutylene is removed from it and the reaction product is obtained.
    Type: Grant
    Filed: May 5, 2006
    Date of Patent: April 19, 2011
    Assignee: Duslo A.S.
    Inventors: Viera Andruskova, Jan Uhlar, Peter Lehocky, Jaroslav Horak
  • Publication number: 20110077393
    Abstract: Disclosed herein are novel methods of using polymeric adsorbent resin for chemical synthesis and the purification of product therefrom. Also disclosed herein is a novel method of using silica gel for the combination of chemical reaction and chromatography into a single step. The methods disclosed herein increase the efficiency of chemical synthesis processes. Accordingly, the utility of the methods disclosed herein includes the ability to automate chemical synthesis and purification of the resulting products.
    Type: Application
    Filed: August 9, 2010
    Publication date: March 31, 2011
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION
    Inventors: Gerald B. Hammond, Bo Xu
  • Patent number: 7888394
    Abstract: Pharmacological inhibition of fatty acid amide hydrolase (FAAH) activity leads to increased levels of fatty acid amides. The alkylcarbamic acid aryl ester of Formula (I), KDS-4103, is a FAAH inhibitor. Described herein is a process for the preparation of the compound of Formula (I), characterization of polymorphs of the FAAH inhibitor, and their uses therof.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: February 15, 2011
    Assignee: N.V. Organon
    Inventors: David Putman, Olivier Dasse
  • Publication number: 20100324159
    Abstract: Embodiments of the present invention are directed to porous resins for solid phase extractions. The resins feature at least one hydrophobic component, at least one hydrophilic component and at least one ion exchange functional group. The resins exhibit superior wetting and ion exchange performance.
    Type: Application
    Filed: August 12, 2010
    Publication date: December 23, 2010
    Applicant: Waters Technologies Corporation
    Inventors: Peter Jeng Jong LEE, John E. O'Gara
  • Publication number: 20100210719
    Abstract: Processes for preparing desvenlafaxine and stable amorphous O-desmethylvenlafaxine succinate solid dispersions with one or more pharmaceutically acceptable carriers.
    Type: Application
    Filed: July 10, 2008
    Publication date: August 19, 2010
    Applicants: DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.
    Inventors: Surya Narayana Devarakonda, Sesha Reddy Yarraguntla, Venu Nalivela, Ram Thaimattam, Subbareddy Peddireddy, Balaji Raghupati, Mohammed Azeezulla Baig, Srinivas Reddy Gade, Srinivas Reddy Mallepalli, Vijaywardhan Chitta, Satyanarayana Bollikonda, Saravanan Mohanarangam, Rajasekhar Kadaboina
  • Patent number: 7772438
    Abstract: The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25-30° C., pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25-30° C. and then stirred for 14 hours at 25-30° C. Filtered the solid and dried at 65° C. for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: August 10, 2010
    Assignee: Hetero Drugs Limited
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Rapolu Raji Reddy, Dasari Muralidhara Reddy, Kesireddy Subash Chander Reddy
  • Patent number: 7772437
    Abstract: The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25-30° C., pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25-30° C. and then stirred for 14 hours at 25-30° C. Filtered the solid and dried at 65° C. for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I.
    Type: Grant
    Filed: February 17, 2009
    Date of Patent: August 10, 2010
    Assignee: Hetero Drugs Limited
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Rapolu Raji Reddy, Dasari Muralidhara Reddy, Kesireddy Subash Chander Reddy
  • Patent number: 7692042
    Abstract: Crude aniline is produced by hydrogenating nitrobenzene in the presence of a catalyst. This crude aniline is then purified by means of a single-step or multi-step distillation process in which aqueous alkali metal hydroxide solution is added to the crude aniline prior to distillation and/or during distillation of the crude aniline.
    Type: Grant
    Filed: February 15, 2007
    Date of Patent: April 6, 2010
    Assignee: Bayer MaterialScience AG
    Inventors: Markus Dugal, Franz-Ulrich Von Gehlen, Stefan Wershofen, Andre Lago, Peter Lehner, Benie Marotz
  • Publication number: 20090306431
    Abstract: An object of the present invention is to provide processes for producing an antiaging agent, a vulcanization accelerator and a modified natural rubber, which are environmentally friendly and capable of making provision against a decrease of petroleum resources in the future. An antiaging agent, a vulcanization accelerator or a modified natural rubber is produced by a method comprising: converting glucose into benzoic acid or a benzoic acid derivative by a microorganism or extracting benzoic acid or a benzoic acid derivative from a plant; and converting the obtained benzoic acid or benzoic acid derivative into aniline or an aniline derivative.
    Type: Application
    Filed: May 21, 2009
    Publication date: December 10, 2009
    Inventor: Keitaro FUJIKURA
  • Patent number: 7598420
    Abstract: The subject invention provides a pharmaceutical composition comprising N-propargyl-1(R)-aminoindan mesylate; a pharmaceutically acceptable carrier; and greater than 0.7 ppm but less than 30 ppm in total of a compound having the structure: and any salts of the compound.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: October 6, 2009
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Jeffrey Sterling, David Lerner, Harel Rosen, Leonid Bronov, Dalia Medini-Green, Berta Iosefzon, Tirtsah Berger-Peskin, Ramy Lidor-Hadas, Eliezer Bahar
  • Publication number: 20090247643
    Abstract: Herbal compositions derived from Kenyan plants are provided for the treatment of HIV and other infectious diseases. The herbal compositions can include the extracts of up to 14 plants, including the root of Dovyalis abyssinica and Clutia robusta. Also provided are methods for extracting alkaloids and other compounds from the plants. Also provided are methods of treating a subject having an infectious disease, particularly HIV.
    Type: Application
    Filed: May 8, 2009
    Publication date: October 1, 2009
    Inventors: Paul Kiprono Chepkwony, Maria Medina, Mitchell Medina
  • Patent number: 7592488
    Abstract: The present invention relates to a method of preparing optically active amines and chiral amines prepared thereby. The method includes reacting an amine compound, a metal catalyst, a biocatalyst including a lipase, and an acyl donor compound in an organic solvent to obtain a chiral amide compound, and then hydrolyzing the chiral amide compound to obtain a chiral amine.
    Type: Grant
    Filed: August 18, 2007
    Date of Patent: September 22, 2009
    Assignee: Postech Academy-Industry Foundation
    Inventors: Mahn-Joo Kim, Jaiwook Park, Won-Hee Kim, Kiwon Han, Yoon Kyung Choi
  • Patent number: 7575660
    Abstract: The invention relates to an energy efficient process for the distillative working-up of aqueous amine solutions that occur in the catalytic hydrogenation of nitroaromatic compounds. In this process, the amine is freed from water and also the water is obtained free from amine and low-boiling compounds and the concentrated low-boiling compounds are obtained.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: August 18, 2009
    Assignee: Bayer MaterialScience AG
    Inventors: Friedhelm Steffens, Rainer Buse, Bill Brady
  • Patent number: 7518019
    Abstract: The present invention discloses novel and improved processes for preparation of sertraline hydrochloride crystalline form II. Thus, for example, sertraline free base is dissolved in isoamyl alcohol at 25-30° C., pH of the mass is adjusted to 2.0 with conc. hydrochloric acid (36%) at 25-30° C. and then stirred for 14 hours at 25-30° C. Filtered the solid and dried at 65° C. for 4 hours to give sertraline hydrochloride crystalline form II. The present invention also provides a novel process for preparation of sertraline hydrochloride crystalline form I.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: April 14, 2009
    Assignee: Hetero Drugs Limited
    Inventors: Bandi Parthasaradhi Reddy, Kura Rathnakar Reddy, Rapolu Raju Reddy, Dasari Muralidhara Reddy, Kesireddy Subash Chander Reddy
  • Patent number: 7507351
    Abstract: Objects of the present invention are to provide a purification process that enables Pd to be removed effectively, and to provide an electroluminescent material and an electroluminescent device obtained by employing the process. The present invention relates to a process for purifying an electroluminescent material, the process involving treating, with a phosphorus-containing material, an electroluminescent material that contains Pd as an impurity so as to remove the Pd.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: March 24, 2009
    Assignees: Hitachi Chemical Co., Ltd., Maxdem Incorporated
    Inventors: Yoshihiro Tsuda, Yoshii Morishita, Satoyuki Nomura, Seiji Tai, Yousuke Hoshi, Shigeaki Funyuu, Farshad J. Motamedi, Li-Sheng Wang
  • Patent number: 7488850
    Abstract: Compounds containing phenolic hydroxy groups are removed from a gas stream which contains at least one aromatic amine generated during the gas-phase hydrogenation reaction of the corresponding nitroaromatic compounds with hydrogen, by adsorption on a basic solid.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: February 10, 2009
    Assignee: Bayer MaterialScience LLC
    Inventors: Knut Sommer, Markus Dugal, Ido Schwarz, Stefan Wershofen, Peter Lehner, Stephan Schubert, Alexandra Groβe Böwing
  • Publication number: 20090012297
    Abstract: A method in one embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having a fluoride anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of about 90° C. or less during the contacting. A method in another embodiment includes contacting a strongly hydrogen bonded organic material with an ionic liquid having an acetate or formate anion for solubilizing the strongly hydrogen bonded organic material; and maintaining the ionic liquid at a temperature of less than about 90° C. during the contacting.
    Type: Application
    Filed: April 23, 2008
    Publication date: January 8, 2009
    Inventors: Philip F. Pagoria, Amitesh Maiti, Alexander Gash, Thomas Yong Han, Christine Orme, Laurence Fried
  • Patent number: 7390927
    Abstract: A process for preparing a 3-aminophenylacetylene compound of formula (5), including: a) reacting a 3-haloaniline compound of formula (1) with an acetylene compound of formula (2) in the presence of a palladium compound, a copper compound, and an amine compound of formula (3) to form an aniline compound of formula (4); b) precipitating the aniline compound of formula (4) in the form of a crystal, and isolating it by solid/liquid separation; and c) reacting the aniline compound of formula (4) with a base to obtain 3-aminophenylacetylene.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: June 24, 2008
    Assignee: FUJILFILM Corporation
    Inventors: Daisuke Urazoe, Hideto Mori
  • Patent number: 7173153
    Abstract: This invention relates to a method for the preparation of sertraline hydrochloride, (1S-cis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphtalenamine hydrochloride, in its crystalline form II.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: February 6, 2007
    Assignee: Recordati Industria Chimica E. Farmaceutica S.p.A.
    Inventors: Fausto Bonifacio, Cristina Crescenzi, Maria Donnarumma, Dimitri Ippoliti
  • Patent number: 7147757
    Abstract: The invention relates to a method for separating by distillation a portion or the entirety of an azeptine derivative (III), which is selected from the group consisting of aminohexylidene imine, tetrahydroazepine, hexylhexahydroazepine and of aminohexylhexahydroazepine, out of a mixture (II) containing an azepine derivative (III) and an amine (I). The inventive method is characterized in that the distillation is carried out with a maximum bottom temperature of 150° C.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: December 12, 2006
    Assignee: Basf Aktiengesellschaft
    Inventors: Hermann Luyken, Frank Ohlbach
  • Patent number: 7122700
    Abstract: A method for bisformylation an arylamine compound by reacting an arylamine compound with an alkyleneamine in a reaction mixture while refluxing an acid in the reaction mixture.
    Type: Grant
    Filed: July 30, 2004
    Date of Patent: October 17, 2006
    Assignee: Xerox Corporation
    Inventors: Timothy P. Bender, Nan-Xing Hu, H. Bruce Goodbrand
  • Patent number: 7067700
    Abstract: Sertraline hydrochloride, (1Scis)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphtalenaminehydrochloride, polymorph II is prepared by extracting or dissolving the sertraline base into ethyl acetate, adding isopropanol as a solvent, adding hydrogen chloride dissolved in ethyl acetate or in gaseous form, and finally isolating and drying sertraline hydrochloride polymorphic form II.
    Type: Grant
    Filed: May 30, 2002
    Date of Patent: June 27, 2006
    Assignee: Fermion Oy
    Inventor: Ilpo Laitinen
  • Patent number: 7057072
    Abstract: A method to convert surplus nitroarene explosives (picric acid, ammonium picrate,) into TATB is described. The process comprises three major steps: conversion of picric acid/ammonium picrate into picramide; conversion of picramide to TATB through vicarious nucleophilic substitution (VNS) of hydrogen chemistry; and purification of TATB.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: June 6, 2006
    Assignee: The Regents of the University of California
    Inventors: Alexander R. Mitchell, Michael D. Coburn, Gregory S. Lee, Robert D. Schmidt, Philip F. Pagoria, Peter C. Hsu
  • Patent number: 7049471
    Abstract: A process comprises contacting a product mixture with a base, optionally in the presence of a polyhydric alcohol, to produce a base-treated mixture and distilling the base-treated mixture in which the product mixture comprises an aromatic amine and a phenolic compound.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: May 23, 2006
    Assignee: E. I. du Pont de Nemours and Company
    Inventors: Carl Andrew Renner, Richard Frank Dubnansky, Freddison A. Parsons, Richard T. Stimek, Zhihong Wu
  • Patent number: 7030276
    Abstract: A process for preparing 2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol with high stereoselectivity and high yield by reacting 2-[(dimethylamino)methyl]-cyclohexanone in a Grignard reaction with a Grignard compound of 3-bromoanisole in a suitable solvent and in the presence of an inorganic lithium salt and an ?,?-dialkoxyalkane.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: April 18, 2006
    Assignee: Gruenenthal GmbH
    Inventors: Michael Finkam, Bernhard Akteries
  • Patent number: 7019174
    Abstract: The invention relates to a process for preparing colourless dibenzylamine by adding ammonium chlorides or amines to the industrially obtained dibenzylamine and subsequent distillation.
    Type: Grant
    Filed: June 24, 2003
    Date of Patent: March 28, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventor: Lutz Heuer
  • Patent number: 6869543
    Abstract: Clear, amine-initiated polyether polyols are made by epoxidizing an amine in the presence of an alkali metal hydroxide catalyst. By reducing the amount of catalyst used during the polyol synthesis and by adding the catalyst after between 5 and 30% of the total amount of at least one alkylene oxide has been added, after lactic acid neutralization, gives a short chain polyol that has foam processing characteristics similar to the conventional sulfuric acid neutralized polyol. The polyols produced in this manner are particularly useful for the production of polyurethane and polyisocyanurate foams.
    Type: Grant
    Filed: February 21, 2003
    Date of Patent: March 22, 2005
    Assignee: Bayer Polymers LLC
    Inventors: Nathan L. Anderson, Karl W. Haider, Keith J. Headley, Kerry A. Ingold, Herman P. Doerge
  • Patent number: 6784320
    Abstract: In a decarbonation process for removing carbon dioxide from a carbon dioxide-containing gas with the use of an amine compound-containing absorbing solution, an amine compound accompanying a decarbonated exhaust gas is efficiently recovered in the following manner: A water washing section is constituted in two stages, a first-stage water washing section 64 and a second-stage water washing section 65. In these water washing sections, recovery of the amine compound accompanying the decarbonated exhaust gas is performed sequentially. Regeneration tower refluxed water is supplied as washing water to the second-stage water washing section 65. Washing water is withdrawn from the second-stage water washing section 65 and supplied to the first-stage water washing section 64. Demisters 83, 84 and 85 are provided at outlets of a carbon dioxide absorption section 73, the first-stage water washing section 64 and the second-stage water washing section 65.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: August 31, 2004
    Assignees: The Kansai Electric Power Co., Inc., Mitsubishi Heavy Industries, Ltd.
    Inventors: Tomio Mimura, Takashi Nojo, Kazuo Ishida, Hiroshi Nakashoji, Hiroshi Tanaka, Takuya Hirata
  • Patent number: 6639102
    Abstract: Polyisocyanates of the diphenyl methane series having reduced color values are obtained by a) reacting aniline and formaldehyde in the presence of an acid catalyst to form a polyamine, b) neutralizing the reaction mixture containing polyamine with a base, c) separating the neutralized mixture into the aqueous and the organic phases, d) adding a base to the organic phase and then e) phosgenating the resulting polyamine to produce the corresponding polyisocyanate.
    Type: Grant
    Filed: March 10, 2003
    Date of Patent: October 28, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Torsten Hagen, Friedhelm Kämper, Daniel Koch, Rudolf Uchdorf, Stefan Wershofen
  • Patent number: 6547933
    Abstract: A process for the purification of a mixture of aromatic polyamines obtained by hydrogenation of the corresponding aromatic polynitro compounds, said mixture including the various isomers of the said amines as well as reaction by-products, including the steps of carrying out a distillation of the mixture in a distillation column, wherein a first stream, corresponding to a fraction or to all of the stream recovered at the bottom of the distillation column, is separated and is used in a chemical reaction and a second stream is separated corresponding (i) to a stream drawn off from the side in the gas phase, in the lower third of the said column, this stream representing at most 20% or more than 80% of the total volume (first and second stream); or (ii) to a fraction of the first stream, this fraction representing 2 to 50% of the volume of the first stream; in order to treat it subsequently.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: April 15, 2003
    Inventors: Philippe Marion, Stephane Montarsolo
  • Patent number: 6515036
    Abstract: A method of recovering a decomposition product from a polyurethane, the method comprising the steps of thermally decomposing a polyurethane into a liquid containing a polyol and a urea compound which is soluble in the polyol, and solids containing a urea compound which is insoluble in the liquid in the presence of a polyamine compound at a temperature of 120 to 250° C.; removing the solids; hydrolyzing the residue with water retained at a high temperature of 200 to 320° C. and a high pressure; and recovering the resulting polyamine and/or polyol.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: February 4, 2003
    Assignee: Mitsui Takeda Chemicals Inc.
    Inventors: Koichi Murayama, Katsuhisa Kodama, Takashi Kumaki
  • Patent number: 6469212
    Abstract: A mixture comprised of about 60-85% of 2,4-toluenediamine (2,4-TDA) and about 15-40% of 2,6-toluenediamine (2,6-TDA) is melted, the temperature of the mixture is lowered to a 2,4-TDA nucleation temperature, and the temperature of the mixture is gradually reduced from the nucleation temperature to about 65 to about 70° C. The resultant mixture is in the form of a solids phase enriched in 2,4-TDA, and a novel and useful liquid phase enriched in 2,6-TDA. These phases are separated. Preferably the solids are further purified by “sweating” them and removing the sweated liquid impurities. The sweated liquid can be recycled together with another charge of a mixture comprised of 2,4-TDA and 2,6-TDA. 2,4-TDA can be produced with a purity of 96-99%.
    Type: Grant
    Filed: March 20, 2000
    Date of Patent: October 22, 2002
    Assignee: Albemarle Corporation
    Inventors: John C. Prindle, Jr., Michael W. Easson, James Dee Palmer, Jason G. Jones, Max K. Mortensen, James E. Boone
  • Publication number: 20020146590
    Abstract: This invention relates to organic electroluminescent elemental devices (organic EL devices) of excellent durability and to organic EL materials useful for such organic EL devices. The organic EL material of this invention comprises a tertiary aryl amine containing 2-4 nitrogen atoms forming triarylamines and, as impurity, compound (A) containing one less nitrogen atoms forming triarylamines than said tertiary aryl amine or compound (B) containing one more nitrogen atoms forming diarylamino groups than said tertiary aryl amine with the content of compound (A) controlled at 1 wt % or less and that of compound (B) at 2 wt % or less.
    Type: Application
    Filed: February 1, 2002
    Publication date: October 10, 2002
    Inventors: Shinji Matsuo, Kazuo Ishii, Hiroshi Miyazaki, Toshinao Yuki, Hitoshi Nakada, Ryuji Murayama, Yasuhiko Sawada, Tsuyoshi Naijo, Yoshinori Fukuda
  • Patent number: 6448446
    Abstract: An improved synthesis of N,N,-disubstituted-p-phenylene-diamine (DSPDA) preferably di-n-butyl-p-phenylenediamine is disclosed. The improvement rests on the discovery that DSPDA and its salts are extremely sensitive to oxygen so that once the product DSPDA or its salt is formed, oxygen must be excluded from all manipulations.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: September 10, 2002
    Assignee: AntiCancer, Inc.
    Inventors: Li Tang, Yuying Tan
  • Patent number: 6429336
    Abstract: Residues from the distillation of a toluene diamine phosgenation mixture are hydrolyzed by mixing them with water and subjecting the mixture to a temperature of 200-350 ° C. The hydrolysis is performed in the presence of a sufficient amount of a base to maintain the pressure in the reactor to no more than a predetermined operating level. The product mixture is then extracted to recover TDA, which can be recycled. This provides an efficient process whereby nearly quantitative conversion of the residues to TDA can be achieved.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: August 6, 2002
    Assignee: The Dow Chemical Company
    Inventors: Shenghong A. Dai, Duane S. Treybig, Kathryn Hock, Van A. Kent