Hemoglobin Patents (Class 600/328)
  • Patent number: 11134890
    Abstract: Aspects relate to a portable device that may be used to identify a critical intensity and an anaerobic work capacity of an individual. The device may utilize muscle oxygen sensor data, speed data, or power data. The device may utilize data from multiple exercise sessions, or may utilize data from a single exercise session. The device may additionally estimate a critical intensity from a previous race time input from a user.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: October 5, 2021
    Assignee: NIKE, Inc.
    Inventors: Brett S. Kirby, Bradley W. Wilkins, David Clark, Eric Bradley, Elizabeth Besemer
  • Patent number: 11107571
    Abstract: Provided is an medical information processing apparatus including processing circuitry that, based on surgical situation information concerning surgical characteristics at a time of observing an interior of a living body, selects at least one of a plurality of biological images each having a different wavelength range or at least one of secondary images generated from the plurality of biological images each having a different wavelength range, as a recommended image.
    Type: Grant
    Filed: April 16, 2020
    Date of Patent: August 31, 2021
    Assignee: SONY CORPORATION
    Inventors: Koji Kashima, Takeshi Uemori, Masahito Yamane, Tsuneo Hayashi
  • Patent number: 11058359
    Abstract: Disclosed is a method of removing motion artifacts from functional near-infrared spectroscopy (fNIRS) signals. The method includes: disposing N optodes at a plurality of locations on a scalp, and forming a plurality of channels between the N optodes; calculating a correlation coefficient difference index of a neighbor channel around each receiver optode, and detecting a receiver optode in which a motion artifact has occurred based on the correlation coefficient difference index; and removing motion artifacts based on the detected receiver optode and an arrangement structure of the N optodes.
    Type: Grant
    Filed: July 6, 2018
    Date of Patent: July 13, 2021
    Assignee: DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Gihyoun Lee, Sang Hyeon Jin, Jinung An
  • Patent number: 11012603
    Abstract: An apparatus for capturing media for capturing media using a plurality of cameras associated with an electronic device based on an ambient light condition is provided. The apparatus includes a processor, and a memory unit coupled to the processor, the memory unit including a processing module configured to obtain at least one preview frame from a first camera in response to enabling an image capture application of the electronic device, determine ambient light parameters of the obtained at least one preview frame, and switch a camera operation of the electronic device from the first camera to a second camera to capture the media, if the determined ambient light parameters are below a pre-defined threshold.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: May 18, 2021
    Inventors: Digadari Suman, Abhijit Dey, Apurbaa Bhattacharjee, Gaurav Khandelwal, Kiran Nataraju
  • Patent number: 10840664
    Abstract: A laser cutting device includes a laser oscillator, a cutting nozzle configured to irradiate a work with laser light so as to cut the work, and a controller configured to control the laser oscillator and a drive unit configured to move the cutting nozzle. The controller includes a laser output control unit, a diagnosis performance determination unit configured to determine, when the laser oscillator satisfies a predetermined operation condition, based on a cutting program, whether or not the laser oscillator is diagnosed, and a diagnosis function performance unit configured to issue a laser output command for diagnosis of the laser oscillator to the laser oscillator. When the diagnosis performance determination unit determines that the laser oscillator is diagnosed, the diagnosis performance determination unit outputs the laser output command for diagnosis to the laser oscillator.
    Type: Grant
    Filed: February 2, 2018
    Date of Patent: November 17, 2020
    Assignee: FANUC CORPORATION
    Inventor: Hiroaki Tokito
  • Patent number: 10791990
    Abstract: A detection system can include a device, a circuit, and at least one indicator. The device can include polymer needle having a distal end and a proximal end. A needle lumen can be extended along a longitudinal axis of the polymer needle. The distal end can include an insertion tip. An elongate sleeve can include a first end and a second end. The polymer needle can be located within an inner bore of the elongate sleeve. The insertion tip of the polymer needle can be disposed at a distance from the elongate sleeve. A first electrode can be coupled to the device and a second electrode can be electrically isolated from the first electrode. The circuit can be configured to provide a signal based on an electrical characteristic between the first electrode and the second electrode. At least one indicator can be communicatively coupled to the circuit and configured to provide an output based on the signal.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: October 6, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Amit Goyal, Michael A. Greminger, Brian J. Krohn, Anastasia N. Zink
  • Patent number: 10705603
    Abstract: A system for detecting invisible human emotion in a retail environment is provided. The system comprises a camera and an image processing unit. The camera is configured in a retail environment to capture an image sequence of a person before and during when a price of a product or service becomes visible. The image processing unit is trained to determine a set of bitplanes of a plurality of images in the captured image sequence that represent the hemoglobin concentration (HC) changes of the person, and to detect the person's invisible emotional states based on HC changes. The image processing unit is trained using a training set comprising a set of subjects for which emotional state is known.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: July 7, 2020
    Assignee: NuraLogix Corporation
    Inventors: Kang Lee, Pu Zheng
  • Patent number: 10650924
    Abstract: Provided is an medical information processing apparatus including processing circuitry that, based on surgical situation information concerning surgical characteristics at a time of observing an interior of a living body, selects at least one of a plurality of biological images each having a different wavelength range or at least one of secondary images generated from the plurality of biological images each having a different wavelength range, as a recommended image.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: May 12, 2020
    Assignee: SONY CORPORATION
    Inventors: Koji Kashima, Takeshi Uemori, Masahito Yamane, Tsuneo Hayashi
  • Patent number: 10575718
    Abstract: An endoscope system captures images of biological tissue when illuminated with first to third light, and generates first to third color image data. The amount of hemoglobin in the biological tissue and the oxygen saturation of the hemoglobin are calculated using components of the first to third color image data, an oxygen saturation distribution image that shows the distribution of the oxygen saturation is generated, and control is performed such that the generated oxygen saturation distribution image is displayed superimposed on a captured image of the biological tissue on a display. The oxygen saturation is calculated based on the amount of hemoglobin and a second ratio obtained using components of the color image data. The transparency is adjusted for pixels in which the value of the second ratio is outside an allowable range for the second ratio determined according to the amount of hemoglobin.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: March 3, 2020
    Assignee: HOYA CORPORATION
    Inventor: Masaaki Fukuda
  • Patent number: 10368798
    Abstract: Systems and methods for monitoring sleep are disclosed. According to an aspect, a method includes emitting light into tissue. The method also includes detecting light backscattered from the tissue. Further, the method includes determining a sleep pattern based on the backscattered light.
    Type: Grant
    Filed: June 29, 2014
    Date of Patent: August 6, 2019
    Assignee: North Carolina State University
    Inventors: Alper Bozkurt, James P. Dieffenderfer
  • Patent number: 10321816
    Abstract: There are provided a light source device, which is more compact and inexpensive than a known light source device, and an endoscope system having a compact and inexpensive light source device. In a light source device, a light source unit includes a first light source that emits blue light, a second light source that emits broadband green light including not only a green component but also a red component, and an optical filter that adjusts the amount of broadband green light for each wavelength. The optical filter has a characteristic in which the reflectance of the green component is smaller than the reflectance of the red component in the case of reflecting the broadband green light or a characteristic in which the transmittance of the green component is smaller than the transmittance of the red component in the case of transmitting the broadband green light.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: June 18, 2019
    Assignee: FUJIFILM Corporation
    Inventors: Yoshinori Morimoto, Satoshi Ozawa
  • Patent number: 10292654
    Abstract: A device for determining a physiological property of a body includes an insulating support having a compliant contact surface with a conductive element to contact the body. A mounting fixture disposed over a mounting surface of the support removably holds a rigid sensor spaced apart from the body and coupled to the conductive element to determine the physiological property via that element. A method for enabling a physiological parameter to be measured without direct contact between an active device and the body includes arranging a conductive element over an inner surface of an insulating circumferential band. A sensor with the active device is attached to the exterior of the band and thus coupled to the element. A system includes the sensor having a mounting connector, and sensor carriers with respective supports, mounting fixtures, and conductive elements. The sensor mounted on a carrier determines the property via the respective conductive element.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: May 21, 2019
    Assignee: Johnson & Johnson Consumer Inc.
    Inventors: Curtis Lee, Ryan Walsh, Alan Trojanowski
  • Patent number: 10070797
    Abstract: A measuring apparatus (100, 200, 300, 400) is an optical measuring apparatus provided with a probe portion (20, 20a, 20b, 20c) and a main body portion (10, 10b, 10c), which are electrically connected to each other. The probe portion has: a light source (21, 26); a reference voltage generating device (24) configured to apply predetermined reference voltage to the main body portion; and a storing device (25) configured to store therein in advance current adjustment information, which is information for adjusting a drive current to be supplied to the light source. The main body portion has: a drive current supplying device (12, 12a, 12b) configured to supply the drive current to the light source, due to the applied reference voltage; and a controlling device (11) configured to control the drive current supplying device on the basis of the stored current adjustment information.
    Type: Grant
    Filed: December 5, 2012
    Date of Patent: September 11, 2018
    Assignee: PIONEER CORPORATION
    Inventor: Kiyoshi Tateishi
  • Patent number: 9693694
    Abstract: Non-invasive apparatus and method for determining and monitoring glucose concentrations in human subjects. Glucose level is estimated through the effect of glucose on biological cells with glucose dependencies, e.g., red blood cells. The invention is based on the interaction of such cells with oscillating electric field gradients. The response of biological cells depends on factors including shape, size, and electrical charge distribution. The field gradient causes the cells to undergo characteristic motion which is detected by light beam scattering. The autocorrelation of the scattered light is computed, and the Fourier transform (FT) is performed to produce a characteristic velocity spectrum in which the peaks are characteristic of the cell “bio-electrical” states. The glucose level is estimated through measurements of changes of FT with changes in glucose levels after calibration with standard glucose methods.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: July 4, 2017
    Inventor: Folim G. Halaka
  • Patent number: 9566025
    Abstract: The present invention is an image based oxygen saturation measuring device and method thereof. The method comprises steps of providing a plurality of red lights and a plurality of infrared lights arranged uniformly in an interlocked fashion and turned on alternatively; controlling the plurality of red lights and infrared lights to irradiate onto a selected skin area of a testee to have a red light turn-on period and an infrared light turn-on period; receiving a reflected version of the plurality of red lights and infrared lights from the selected skin area, respectively; and analyzing one reflected red light and one infrared light to acquire an oxygen saturation index for each of the coordination points. By means of the present invention, the measurement of oxygen saturation may be much exempted from effects brought from exterior interference and poor blood circulation, and may achieve a large measurement area in a single time.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: February 14, 2017
    Assignee: NATIONAL APPLIED RESEARCH LABORATORIES
    Inventors: Hsin-Yi Tsai, Kuo-Cheng Huang, Yi-Ju Chen, Han-Chao Chang
  • Patent number: 9468380
    Abstract: A system and method for identifying metabolic activity within the heart muscle (myocardium). Metabolic activity is determined through spectrographic analysis of the myocardium. More particularly, oxygen saturation of the myocardium is measured through the spectrographic analysis, and metabolic activity is measured by a decrease in oxygen saturation of the myocardium over time.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: October 18, 2016
    Assignee: Children's Hospital Medical Center
    Inventors: Russel Hirsch, John Miras Racadio
  • Patent number: 9398877
    Abstract: Disclosed is a method and a device for optical imaging of a turbid medium. This method comprises a reference measurement of reference intensities of light emanating from the turbid medium at a reference blood oxygen saturation (SaO2) in the turbid medium and a reference imaging step for reconstructing a reference image of the turbid medium from the measured reference intensities. Furthermore the method comprises a contrast measurement of the contrast intensity of the light emanating from the turbid medium at a contrast blood oxygen saturation (SaO2) level in the turbid medium and a contrast imaging step for reconstructing a contrast image of the turbid medium from the measured contrast intensities. A comparison is made between the contrast image to the reference image of the turbid medium.
    Type: Grant
    Filed: November 17, 2006
    Date of Patent: July 26, 2016
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Martinus Bernardus Van Der Mark, Michael Cornelis Van Beek, Levinus Pieter Bakker
  • Patent number: 9277964
    Abstract: Wave energy is directed into a body. A condition within the body is observed by reflection from effects within the body. An internal target is located. Wave energy is focused on the target within the body and is increased in intensity to treat the target. A hand held instrument passivates or moves scalp from a skull, and converges, diverges or collimates near infrared laser beams through a skull and into interior tissue. Reflected energy reveals vessels edema or bleeding. Vessel targets are identified. Infrared laser beams are directed, triggered and intensified to coagulate or constrict the vessel. The hand held instrument is a wand connected to a laser source, processor, display and power source. The power supply, processor, infrared laser, display and laser director are mounted on a hand held unit for field use by technicians and medics to prevent time delay and further injury.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: March 8, 2016
    Assignee: OCEANIT LABORATORIES, INC.
    Inventor: Thomas Alan Hasling
  • Patent number: 9131881
    Abstract: Embodiments of the present disclosure provide a hypersaturation index for measuring a patient's absorption of oxygen in the blood stream after a patient has reached 100% oxygen saturation. This hypersaturation index provides an indication of the partial pressure of oxygen of a patient. In an embodiment of the present invention, a hypersaturation index is calculated based on the absorption ratio of two different wavelengths of energy at a measuring site. In an embodiment of the invention, a maximum hypersaturation index threshold is determined such that an alarm is triggered when the hypersaturation index reaches or exceeds the threshold. In another embodiment, an alarm is triggered when the hypersaturation index reaches or falls below its starting point when it was first calculated.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: September 15, 2015
    Assignee: Masimo Corporation
    Inventors: Mohamed K. Diab, Prashanth Iyengar, Anand Sampath, Ammar Al-Ali
  • Publication number: 20150148625
    Abstract: An improved sensor (102) for respiratory and metabolic monitoring in mobile devices, wearables, security, illumination, photography, and other devices and systems uses an optional phosphor-coated broadband white LED (103) to produce broadband light (114), which is then transmitted along with any ambient light to a target (125) such as the ear, face, or wrist of a living subject. Some of the scattered light returning from the target to detector (141) is passed through narrowband spectral filter set (155) to produce multiple detector regions, each sensitive to a different waveband wavelength range, and the detected light is spectrally analyzed to determine a measure of respiration of the subject, such as respiratory rate, volume, effort, depth, or respiratory variability.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventor: David Alan Benaron
  • Publication number: 20150148624
    Abstract: An improved sensor (102) for physiology monitoring in mobile devices, wearables, security, illumination, photography, and other devices and systems uses broadband light (114) transmitted to a target (125) such as the ear, face, or wrist of a living subject. Some of the scattered light returning from the target to detector (141) is passed through narrowband spectral filter set (155) to produce multiple detector regions, each sensitive to a different wavelength range.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventor: David Alan Benaron
  • Publication number: 20150148635
    Abstract: An improved sensor (102) for rate monitoring in mobile devices, wearables, security, illumination, photography, and other devices and systems uses an optional phosphor-coated broadband white LED (103) to produce broadband light (114), which is then transmitted along with any ambient light to target (125) such as the ear, face, or wrist of a living subject. Some of the scattered light returning from the target to detector (141) is passed through spectral filter set (155) to produce multiple detector regions, each sensitive to a different waveband wavelength range, and the detected light is analyzed to determine an interval between repetitive events such as heartbeat or respirations, in part based on a noninvasive measure of components of the bloodstream.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventor: David Alan Benaron
  • Publication number: 20150148636
    Abstract: An improved sensor (102) for respiratory and metabolic monitoring in mobile devices, wearables, security, illumination, photography, and other devices and systems uses a broadband ambient light (114), which is then transmitted to a target (125) such as the ear, face, or wrist of a living subject. Some of the scattered light returning from the target to detector (141) is passed through spectral filter set (155) to produce multiple detector regions, each region sensitive to a different narrowband wavelength range, and the detected light is spectrally analyzed to determine a measure of a physiology of the subject such as pulse, respiration, hydration, calories. Additional broadband light can be added when ambient light alone may be sufficient illumination for analysis.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventor: David Alan Benaron
  • Publication number: 20150118689
    Abstract: A system comprised of a device for measuring hemoglobin content and/or determining a hematocrit value and/or measuring a hematocrit value, and a device for measuring or detecting an analyte, and a method for measuring or determining the presence of at least one analyte are described.
    Type: Application
    Filed: October 23, 2014
    Publication date: April 30, 2015
    Inventors: Richard L. Egan, Larry Thomas Mimms, Ferda Yantiri-Wernimont
  • Publication number: 20150119665
    Abstract: Optical data is obtained from a pair of breasts, employing a simultaneous bilateral referencing protocol, and is subsequently analyzed employing a self-referencing data analysis method. Optical measurements can be performed on both breasts simultaneously under various protocols, including resting-state measures and evoked responses. Sensing hardware and data collection protocols are economical and can be implemented without patient discomfort. The natural variance inherently associated with optical measures of the breast is reduced by: imposition of substantially symmetric boundary conditions; collection of simultaneous bilateral dynamic measures; referencing measurement data of one breast to measurement data from another.
    Type: Application
    Filed: April 25, 2013
    Publication date: April 30, 2015
    Applicant: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
    Inventors: Randall L. Barbour, Rabah M. Al Abdi
  • Publication number: 20150105638
    Abstract: A system and method for measuring one or more light-absorption related blood analyte concentration parameters of a mammalian subject, is disclosed. In some embodiments, the system comprises: a) a photoplethysmography (PPG) device configured to effect a PPG measurement by illuminating skin of the subject with at least two distinct wavelengths of light and determining relative absorbance at each of the wavelengths; b) a dynamic light scattering measurement (DLS) device configured to effect a DLS measurement of the subject to rheologically measure a pulse parameter of the subject; and c) electronic circuitry configured to: i) temporally correlating the results of the PPG and DLS measurements; and ii) accordance with the temporal correlation between the PPG and DLS measurements, assessing value(s) of the one or more light-absorption related blood analyte concentration parameter(s).
    Type: Application
    Filed: October 1, 2014
    Publication date: April 16, 2015
    Inventors: Leon Eisen, Alexander Kaminsky, IIya Fine
  • Publication number: 20150087939
    Abstract: There is provided a system and method for canceling shunted light. The method includes transmitting electromagnetic radiation at tissue of interest and generating a signal representative of detected electromagnetic radiation. A portion of the generated signal representing shunted light is canceled from the generated signal and the remaining portion of the generated signal is used to compute physiological parameters.
    Type: Application
    Filed: December 9, 2014
    Publication date: March 26, 2015
    Inventor: Ethan Petersen
  • Publication number: 20150073241
    Abstract: The present disclosure provides systems and methods for calibrating medical devices and processing physiological measurements using a medical device management system. As an example, the medical device can be a handheld glucometer configured for invasive testing and non-invasive testing of physiological parameters of a patient.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 12, 2015
    Inventor: Marcelo M. Lamego
  • Publication number: 20150051464
    Abstract: A concentration measurement apparatus includes a probe, having a light incidence section making measurement light incident on the head and a light detection section detecting the measurement light that has propagated through the interior of the head, a CPU determining a temporal relative change amount of oxygenated hemoglobin concentration and performing a filtering process of removing frequency components less than a predetermined frequency from frequency components contained in the relative change amount, and a display section displaying first time series data indicating the filtering-processed relative change amount. The CPU judges whether or not chest compression is being performed. If chest compression is not performed for a predetermined time, the display section switches from displaying the first time series data to displaying second time series data indicating the relative change amount that contains frequency components less than the predetermined frequency.
    Type: Application
    Filed: December 25, 2012
    Publication date: February 19, 2015
    Applicant: HAMAMATSU PHOTONICS K.K.
    Inventors: Takeo Ozaki, Susumu Suzuki
  • Publication number: 20150038812
    Abstract: Described herein are fNIR-based brain computer interfaces. Training of individuals to intentionally control neural activity in specific cortical areas, thereby up-regulating and down-regulating oxygenation levels in specific locations in the brain is also provided herein. Further, continuous and/or binary control over computing environments using fNIR brain computer interfaces. Further still, a scale for brain interface index for oxygenation of a portion of the brain is provided herein.
    Type: Application
    Filed: March 23, 2012
    Publication date: February 5, 2015
    Applicant: Drexel University
    Inventors: Hasan Ayaz, Patricia A. Shewokis, Scott C. Bunce, Banu Onaral
  • Publication number: 20150038813
    Abstract: A photoacoustic diagnosis device that diagnoses a state of a skin of a human body, includes a pulsed light source, an electric signal converter, a blood distribution obtaining section, and a diagnosis section. The pulsed light source generates a pulsed light. The electric signal converter receives a photoacoustic wave generated at the skin by the pulsed light and converts the photoacoustic wave into an electric signal. The blood distribution obtaining section obtains distribution of blood in the skin based on the electric signal. The diagnosis section diagnoses a state of the skin based on a result obtained by the blood distribution obtaining section.
    Type: Application
    Filed: May 2, 2013
    Publication date: February 5, 2015
    Inventors: Yasushi Kawaguchi, Taiichiro Ida
  • Publication number: 20150025344
    Abstract: An apparatus and method for non-invasively determining a blood oxygen parameter value of a subject's tissue is provided. An embodiment of the method includes the steps of: a) providing a spectrophotometric sensor that includes a processing portion and a transducer, b) detecting at least a portion of transmitted light after passage through the subject's tissue and producing initial signal data from the detected light; and c) using the processing portion to: (i) determine a value representative of an attenuation of at least one wavelength of light detected; (ii) determine whether the representative attenuation value is outside a predefined range of attenuation values; and (iii) determine the blood oxygen parameter value using a first interrogation or an alternate interrogation setting.
    Type: Application
    Filed: July 18, 2014
    Publication date: January 22, 2015
    Inventor: Paul Benni
  • Publication number: 20150025343
    Abstract: An optical system for the detection of skin disease, such as melanoma, acquires images of a lesion on a subject's skin at different wavelengths and utilizes a sweeping arm rotating about the lesion in a clock-like sweep to produce diagnostically relevant metrics and classifiers from the image data so as to enhance detection of the skin disease.
    Type: Application
    Filed: October 10, 2013
    Publication date: January 22, 2015
    Applicant: The Rockefeller University
    Inventors: Daniel Gareau, Justin Martin
  • Publication number: 20150018654
    Abstract: What is disclosed is a system and method for monitoring a subject of interest for fractional blood oxygen saturation using an apparatus that can be comfortably worn by the subject around an area of exposed skin where a photoplethysmographic (PPG) signal can be registered. In one embodiment, the apparatus is a reflective or transmissive wrist-worn device with emitter/detector pairs fixed to an inner side of a band with at least three illuminators, each emitting source light at a different wavelength band. Each photodetector comprises sensors that are sensitive to a wavelength band of a respective illuminator. Each photodetector measures an intensity of sensed light emitted by a respective illuminator. The signal obtained by the sensors comprises a continuous PPG signal. The continuous PPG signal analyzed for fractional blood oxygen saturation levels and communicated to a remote device. Various embodiments are disclosed.
    Type: Application
    Filed: July 9, 2013
    Publication date: January 15, 2015
    Inventors: Lalit Keshav MESTHA, Barry P. MANDEL, Peter Johan NYSTROM
  • Publication number: 20150005599
    Abstract: An object information acquiring apparatus is used which includes: a laser medium; a temperature controlling unit for controlling a temperature of the laser medium; an excitation unit for exciting the laser medium; a control unit for controlling the temperature controlling unit and the excitation unit; a probe for receiving acoustic waves that are generated when an object is irradiated with a laser beam from the laser medium; and a processing unit for acquiring characteristic information relating to the object from the acoustic waves, wherein the control unit does not operate the excitation unit until the temperature of the laser medium falls within a predetermined range.
    Type: Application
    Filed: June 17, 2014
    Publication date: January 1, 2015
    Inventor: Koichi Suzuki
  • Publication number: 20140378796
    Abstract: The present invention provides a monitoring system, which comprises a novel needle, and an optical signal generating device, wherein at least one optical signal output of the optical signal generating device is coupled to the optical core of the needle, and it further comprises an ultrasound (US) transducer,and a processor adapted to direct the US transducer to transmit an US signal into a region of a subject in which the needle is moving and receive an US signal reflected in the region in response to the transmitted US signal in a US measurement sub-cycle of a measurement cycle, and to direct the optical signal providing device to transmit an optical signal having a unique wavelength from the dome of the needle into an area of the region and direct the US transducer to receive a photo-acoustic (PA) signal induced in the area in response to the optical signal in each of at least one PA measurement sub-cycle of the measurement cycle, and reconstruct an US image from the US signal received in the US measurement
    Type: Application
    Filed: December 27, 2012
    Publication date: December 25, 2014
    Inventors: Yinan Chen, Jingping Xu, Junbo Li, Yunrong Zhang
  • Patent number: 8917442
    Abstract: The present disclosure provides various systems and methods for focusing electromagnetic radiation (EMR) within a diffusion medium, such as a turbid medium. A diffusion medium is irradiated with EMR. The EMR may be modulated by an acoustical wave focused on a focus volume within the diffusion medium. The EMR may be modulated by a beat frequency or other function of multiple focused acoustical waves. The EMR may be modulated at a harmonic of a fundamental frequency of one or more acoustical waves. A filter may filter the emerging EMR to remove all but specifically modulated EMR scattered from the focus volume. The modulated EMR may be focused and/or used for various purposes, including imaging. In some embodiments, the modulated EMR may be reflected and/or amplified by a phase conjugating mirror. Furthermore, in some embodiments, acoustical phase conjugation may be used to focus an acoustical wave on a focus volume.
    Type: Grant
    Filed: September 20, 2012
    Date of Patent: December 23, 2014
    Assignee: Elwha LLC
    Inventors: Michael H. Baym, Roderick A. Hyde, Jordin T. Kare, Lowell L. Wood, Jr.
  • Publication number: 20140371557
    Abstract: A biological signal measuring system includes: a light emitter emitting light beams having different N kinds of wavelengths, where N is an integer of four or more; a light receiver outputting N kinds of signals respectively in accordance with received light intensities of the N kinds of light beams that have been passed through or reflected from a living tissue; a first calculating section acquiring N kinds of light attenuations based on the N kinds of signals; a second calculating section acquiring (N?1) kinds of blood-derived light attenuations based on two light attenuations related to (N?1) kinds of combinations selected from the N kinds of light attenuations; a third calculating section identifying concentrations of (N?1) kinds of in-blood substances based on the (N?1) kinds of blood-derived light attenuations; and an outputting section outputting the identified concentrations.
    Type: Application
    Filed: May 23, 2014
    Publication date: December 18, 2014
    Applicant: NIHON KOHDEN CORPORATION
    Inventors: Naoki Kobayashi, Hideaki Hirabara
  • Publication number: 20140350366
    Abstract: According to one embodiment, a photoelectric conversion device including a substrate having opaque interconnection layers, an insulating film formed on the substrate, and having a plurality of openings, light-emitting elements formed of the openings, each light-emitting element having an upper electrode layer, and light-receiving elements formed of the openings, each light-receiving element having an upper electrode layer, wherein a semiconductor material is different in the light-emitting element and the light-receiving element, the upper electrode layer both of the light-emitting element and the light-receiving element are formed as common electrodes, and each interconnection layer is formed on a region outside a region specified by the opening.
    Type: Application
    Filed: August 13, 2014
    Publication date: November 27, 2014
    Applicant: KABUSHIKI KAISHA TOSHIBA
    Inventor: Masahiko AKIYAMA
  • Publication number: 20140343384
    Abstract: Disclosed are fiber optic devices and related methods that allow for measurement of blood flow and oxygenation in real time. These devices have particular application to the spinal cord. Such devices have applicability in, for example, the care of military members sustaining combatant and noncombatant spinal injuries, as well as to civilians. The devices also have utility in the acute and subacute management of spine trauma, enhancing the efficacy of interventions aimed at the prevention of secondary ischemic injury, and ultimately improving neurologic outcome.
    Type: Application
    Filed: December 14, 2012
    Publication date: November 20, 2014
    Inventors: Thomas F. Floyd, Arjun G. Yodh, Rickson C. Mesquita
  • Publication number: 20140303464
    Abstract: Disclosed are methods and devices for measuring a state of anesthesia in a noninvasive manner. Optical techniques may be used to measure changes in a functional near-infrared (fNIR) signal, where the fNIR signal is received in response to directing wavelengths of light in a near-infrared range on a patient. The optical density change may be used to obtain a change in deoxyhemoglobin (deoxy-Hb) concentration and/or a change in an oxyhemoglobin concentration (oxy-Hb). The changes in the deoxy-Hb and/or the oxy-Hb may then be compared to determine a state of anesthesia. The effect of artifacts (e.g., strong surgery room lighting, patient-table tilting, patient intubation/extubation) on the fNIR signal may be removed using a noise removal algorithm. In selecting the noise removal algorithm, a switching technique may be used to select the component analysis algorithm, such as a principal component analysis (PCA), an independent component analysis (ICA), or the like.
    Type: Application
    Filed: June 17, 2014
    Publication date: October 9, 2014
    Inventors: Kurtulus IZZETOGLU, Kambiz POURREZAEI, Banu ONARAL, Jay Charles HORROW, Meltem Alkan IZZETOGLU, Scott C. Bunce
  • Patent number: 8852094
    Abstract: A physiological parameter system has one or more parameter inputs responsive to one or more physiological sensors. The physiological parameter system may also have quality indicators relating to confidence in the parameter inputs. A processor is adapted to combine the parameter inputs, quality indicators and predetermined limits for the parameters inputs and quality indicators so as to generate alarm outputs or control outputs or both.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: October 7, 2014
    Assignee: Masimo Corporation
    Inventors: Ammar Al-Ali, John Graybeal, Massi E. Kiani, Michael Petterson, Chris Kilpatrick
  • Publication number: 20140275891
    Abstract: Optical sensors, systems, and methods are described, which may be used to provide or analyze information about a subject. The optical sensor may be placed in proximity to the subject and may include optical sources and optical detectors. The optical sources may irradiate the subject with optical signals and the optical detectors can detect signals from the subject. Analysis of the detected signals can yield information about the subject.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Cephalogics, LLC
    Inventors: Thomas Muehlemann, Catherine Pace, Karim Haroud, Stefan Troller, Azadeh Khanicheh, Jeffery J. Caputo, Russell L. Herrig, Joseph Culver
  • Publication number: 20140275871
    Abstract: Embodiments of the disclosure include a noninvasive physiological patient sensor and a patient monitor capable of wireless communication with one another. An optical communication path can be used to provide the communication path between the noninvasive physiological patient sensor and the patient monitor. The path can be maintained by one or more light sources and detectors traditionally associated with noninvasive optical sensors or by one or more additional dedicated light sources and detectors.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: CERCACOR LABORATORIES, INC.
    Inventors: Marcelo M. Lamego, Massi Joe E. Kiani
  • Publication number: 20140249390
    Abstract: A process and apparatus for determining the arterial and venous oxygenation of blood in vivo with improved precision. The optical properties of tissue are measured by determination of differential and total attenuations of light at a set of wavelengths. By choosing distinct wavelengths and using the measured attenuations, the influence of variables such as light scattering, absorption and other optical tissue properties is canceled out or minimized.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 4, 2014
    Inventor: Peter Bernreuter
  • Publication number: 20140206957
    Abstract: A method and an optical system for evaluating the spatial distribution of the concentrations of components in tissue are disclosed. The novel detecting probe included in the optical system comprises plural optical fiber sets, each optical fiber set respectively comprises at least one source optical fiber and at least one detector optical fiber, the source optical fiber connects with the multi-wavelength light source, the source optical fiber delivers light from the multi-wavelength light source onto a tested tissue; and the angle between one optical fiber set and another optical fiber set is greater than 0° and less than and not equal to 180°. Through the optical system of the present invention, the spatial distribution of the concentrations of components such as water, hemoglobin, melanin, lipid, and collagen in the tested tissue can be derived by an equation (I) defined in the present specification.
    Type: Application
    Filed: July 17, 2013
    Publication date: July 24, 2014
    Inventors: Sheng-Hao TSENG, Chao-Kai HSU, Shih-Yu TZENG, Nan-Yu CHENG
  • Publication number: 20140155716
    Abstract: A tissue oximetry device utilizes at least three or at least four different wavelengths of light for collection of reflectance data where the different wavelengths are longer than 730 nanometers. The three or four wavelengths are utilized to generate a range of reflectance data suited for accurate determination of oxygenated hemoglobin and deoxygenated hemoglobin concentrations. The relatively long wavelengths decrease optical interference from certain dyes, particularly methylene blue and PVPI, which may be present on tissue being analyzed for viability and further enhance the generation of accurate reflectance data. The wavelengths are 760 nanometers, 810 nanometers, and 850 nanometers, or 760 nanometers, 810 nanometers, 850 nanometers, and 900 nanometers.
    Type: Application
    Filed: May 3, 2013
    Publication date: June 5, 2014
    Applicant: VIOPTIX, INC.
    Inventor: ViOptix, Inc.
  • Publication number: 20140128697
    Abstract: A sleep apnea diagnostic system includes a housing that is configured to be attached to near the nose of a patient's face to sense physiological information of a patient. The housing includes sensors to sense the physiological information. The physiological information may be, for example, air flow through the nose or the mouth or both. The physiological information further may be, for example, blood volume. The sleep apnea diagnostic system includes at least one processor in the housing or external to the housing or both to analyze the physiological information to determine whether the patient has experienced irregular or abnormal respiratory activity and to detect respiratory effort. The analysis may be real time or delayed.
    Type: Application
    Filed: March 14, 2013
    Publication date: May 8, 2014
    Applicant: SOMNARUS INC.
    Inventor: Somnarus Inc.
  • Publication number: 20140094668
    Abstract: According to the present invention, a method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided. The method comprises the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) detecting light after passage through the subject's tissue using the sensor, and producing initial signal data from the light sensed; c) calibrating the sensor to that particular subject using the initial signal data, thereby accounting for the specific physical characteristics of the particular subject's tissue being sensed; and d) using the calibrated sensor to determine the blood oxygen parameter value within the subject's tissue.
    Type: Application
    Filed: March 11, 2013
    Publication date: April 3, 2014
    Applicant: CAS MEDICAL SYSTEMS, INC.
    Inventor: Paul B. Benni
  • Publication number: 20140078578
    Abstract: The present disclosure provides various systems and methods for focusing electromagnetic radiation (EMR) within a diffusion medium, such as a turbid medium. A diffusion medium is irradiated with EMR. The EMR may be modulated by an acoustical wave focused on a focus volume within the diffusion medium. The EMR may be modulated by a beat frequency or other function of multiple focused acoustical waves. The EMR may be modulated at a harmonic of a fundamental frequency of one or more acoustical waves. A filter may filter the emerging EMR to remove all but specifically modulated EMR scattered from the focus volume. The modulated EMR may be focused and/or used for various purposes, including imaging. In some embodiments, the modulated EMR may be reflected and/or amplified by a phase conjugating mirror. Furthermore, in some embodiments, acoustical phase conjugation may be used to focus an acoustical wave on a focus volume.
    Type: Application
    Filed: September 20, 2012
    Publication date: March 20, 2014
    Applicant: ELWHA LLC
    Inventors: Michael H. Baym, Roderick A. Hyde, Jordin T. Kare, Lowell L. Wood, Jr.