Holder For Color Indicator (e.g., Fertility Tester) Patents (Class 600/367)
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Patent number: 11272844Abstract: [Problem] To predict a remaining time during which a fluorescence image is observable. [Solution] An information processing device according to the present disclosure includes a remaining time estimation unit that estimates, on the basis of a luminance limit value for observation of a fluorescence image and a change in luminance of a fluorescence image, a remaining time until the luminance of the fluorescence image reaches the luminance limit value. This configuration enables the time at which the luminance of a fluorescence image reaches the luminance limit value to be estimated according to a change in luminance of the fluorescence image, and it is possible to predict a remaining time during which a fluorescence image is observable.Type: GrantFiled: October 18, 2018Date of Patent: March 15, 2022Assignee: SONY CORPORATIONInventors: Takami Mizukura, Minori Takahashi, Kenji Takahashi, Kentaro Fukazawa
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Patent number: 9551701Abstract: A method for detecting an analyte in a bodily fluid includes placing the detector in contact with at least one metabolite resulting from the metabolism or degradation of the analyte. The contact between the detector and the metabolite produces an optically detectable signal. The detection method includes the detection of the metabolite only in gas form, said metabolite in gas form coming from the evaporation of at least a part of said metabolite. The detection is also carried out without contact between the bodily fluid and the detector. A dressing for implementing the detection method is also described.Type: GrantFiled: December 29, 2010Date of Patent: January 24, 2017Assignee: COMMISSARIAT À L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Gilles Marchand, Pierre Marcoux
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Patent number: 9304088Abstract: A method of measuring a pH of a solution includes: emitting light beams of two wavelengths from one side of a measuring region of a solution into which an indicator is mixed, while pulsating the solution in the measuring region; receiving at least one of transmitted light beams and reflected light beams of the emitted light beams on the other side of the measuring region, while pulsating the solution in the measuring region; obtaining absorbances of the two wavelengths based on the received at least one of the transmitted light beams and the reflected light beams; obtaining an absorbance ratio from the obtained absorbances; and calculating a pH value of the solution based on the obtained absorbance ratio and an absorbance ratio/pH value correspondence database which is previously stored.Type: GrantFiled: February 19, 2012Date of Patent: April 5, 2016Assignees: NIHON KOHDEN CORPORATION, TOKYO WOMEN'S MEDICAL UNIVERSITYInventors: Mitsuhiro Oura, Teruo Okano, Tatsuya Shimizu, Hirotsugu Kubo, Sunao Takeda, Shinji Yamamori
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Publication number: 20140350372Abstract: The present invention provides a device for an energizable Ophthalmic Lens with an event coloration mechanism. The event coloration mechanism may color or change color based on some predefined event. For example, a predefined constituent or predefined condition of the tear fluid may be indicative of the predefined event, and the event coloration mechanisms may interact with the tear fluid, accordingly. The event coloration mechanism may provide the energizable functionality of the Ophthalmic Lens in some embodiments. In others, the event coloration mechanism may be passive but may interact and interface with the electrical components of the Ophthalmic Lens, such as, for example, those included within the Media Insert. Event coloration mechanisms may be combined with additional functionalities that may be included in an energizable Ophthalmic Lens.Type: ApplicationFiled: May 21, 2013Publication date: November 27, 2014Applicant: Johnson & Johnson Vision Care, Inc.Inventors: Randall B. Pugh, Karson S. Putt, Camille Higham, Sharika Snook
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Publication number: 20140350373Abstract: The present invention provides for an Ophthalmic Lens device with passive event coloration mechanisms, which may not require a power source. An Ophthalmic Lens may comprise multiple event coloration mechanisms, wherein the event coloration mechanisms may or may not comprise similar embodiments. The event coloration mechanism may color or change color based on some predefined event. A predefined constituent or predefined condition of the tear fluid may be indicative of the predefined event, and the event coloration mechanisms may interact with the tear fluid, accordingly. In some embodiments, the passive event coloration mechanisms may be combined with Rigid Inserts or Media Inserts, wherein the inserts may provide additional functionalities.Type: ApplicationFiled: May 21, 2013Publication date: November 27, 2014Applicant: Johnson & Johnson Vision Care, Inc.Inventors: Randall B. Pugh, Karson S. Putt, Camille Higham, Sharika Snook
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Publication number: 20140336488Abstract: Disclosed are probes, systems, and devices that can be used to assay the presence of a biomarker in the sinus of a patient. The probes, systems, and devices can be used to contact the sinus fluid inside the sinus of a patient with an immunoassay for the presence of a biomarker that is characteristic of sinusitis. The probes can therefore be used to determine the underlying cause of sinusitis in a patient. Also provided are methods of treating sinusitis by administering to a patient a therapeutic regimen selected in view of a biomarker detected in the sinus of the patient. As the biomarker is associated with one or more causative agents of sinusitis, a therapy effective to treat the underlying causative agent can be selected.Type: ApplicationFiled: September 14, 2012Publication date: November 13, 2014Applicant: The Ohio State UniversityInventor: Subinoy Das
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Publication number: 20140275868Abstract: Some embodiments provide a system for synchronizing and configuring monitoring devices. In some embodiments, a patient monitoring device settings module is configured to automatically provide configuration settings to a plurality of patient monitoring devices. A monitoring device data module is configured to receive measurement data from at least one of the patient monitoring devices. An electronic medical records system interface is configured to provide patient data at least partially derived from the received measurement data to an electronic medical records system. A patient records interface is configured to provide patient data to at least one of the patient monitoring devices.Type: ApplicationFiled: November 22, 2013Publication date: September 18, 2014Applicant: OptiScan Biomedical CorporationInventors: Peter Rule, Gil Rivas
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Publication number: 20140275908Abstract: The present invention is directed to medical articles which exhibit a color change upon exposure to an analyte of interest and to methods of detecting analytes in bodily fluid using the same.Type: ApplicationFiled: February 26, 2014Publication date: September 18, 2014Applicant: Boston Scientific Scimed, Inc.Inventors: Nathan Zamarripa, Jeff Gray
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Publication number: 20140206956Abstract: In vivo devices, systems and methods for in vivo immunoassay include inserting into a patient's body lumen an in vivo diagnostic device comprising a housing. The housing of the device comprises a chamber, and a chromatography strip for immunoassay of a body lumen substance. The housing may further comprise a casing for the chromatography strip. The casing may comprise a first opening to allow entrance of in vivo liquids into the casing and a second opening into the chamber. The housing may further comprise a sensor to sense a property of the chromatography strip. Following insertion of the device into the patient's body, a sample is collected and the immunoassay is performed in vivo in areas of pathological lesions for a predetermined period of time. An in vivo image may be acquired or other data such as colorimetric or intensity data may be obtained from the chromatography strip.Type: ApplicationFiled: August 1, 2012Publication date: July 24, 2014Inventors: Elisha Rabinovitz, Zvika Gilad, Osnat Sella-Tavor, Amit Pascal
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Publication number: 20140187892Abstract: The disclosure provides an allergy detection system for use during catheterization. The allergy detection system is incorporated into specialized syringes, connectors for use with standard syringes, or can be an independent test module designed for the sole purpose of allergy detection. The detection system features a test strip, such as an immunochromatographic test strip, and a structure to couple the system to a connector, syringe, or a housing, to form an independent test module. The detection system, by way of test strips, is used to detect potential allergic reactions.Type: ApplicationFiled: November 29, 2012Publication date: July 3, 2014Inventors: Nisha Gupta, David T. Rowe, Rodney W. Denlinger
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Publication number: 20140148671Abstract: Disclosed herein are compositions and methods for detecting an anastomosis leakage at the tubular tissue of a subject. The method can include applying a composition to an exterior of an anastomosis site in the tubular tissue of said subject and monitoring a urine color of the subject after the composition is applied. The composition may include a bioabsorbable binding medium and a biocompatible chromophore at least partially encapsulated in the bioabsorbable binding medium. Also disclosed are implantable films including: a first layer having a first bioabsorbable polymer and a biocompatible chromophore; and a second layer having a second bioabsorbable polymer. The biocompatible chromophore can be embedded within the bioabsorbable polymer. The second layer can be substantially free of the bioabsorbable polymer.Type: ApplicationFiled: July 5, 2012Publication date: May 29, 2014Applicant: EMPIRE TECHNOLOGY DEVELOPMENT LLCInventors: George Charles Peppou, Michael Keoni Manion, Deniz Ozdil
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Publication number: 20140066726Abstract: A biological sample collection device includes a top cover plate, a bottom portion attached to the top cover plate, the bottom portion comprising a remotely-analyzable biological sample collection portion to collect a biological sample from a body of a subject. The biological sample is to be analyzed at a remote processing facility at a later time. A fastening portion is provided on the bottom portion to affix the remotely-analyzable biological sample collection device to the body of the subject. A real time clock is coupled to the top cover plate and a memory is coupled to the top cover plate and electrically coupled to the real time clock. The remotely-analyzable biological sample collection device may further include a processing unit, at least two electrodes coupled to the processing unit, and a transbody conductive communication module.Type: ApplicationFiled: March 8, 2012Publication date: March 6, 2014Applicant: PROTEUS DIGITAL HEALTH, INC.Inventor: Benedict Costello
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Publication number: 20130303862Abstract: A system and method allows diagnosis of a patient for physiological abnormality such as a neurological deficiency. An involuntary reflex cough event is induced within the patient that activates the nucleus ambiguus and medial motor cell column of the patient and stimulates involuntary cough activated paraspinal muscles in the pelvis of the patient. An electromyogram (EMG) is obtained from the involuntary cough activated paraspinal muscles while inducing involuntary reflex cough and determining its duration. The intra-abdominal pressure (IAP) is determined and the IAP is correlated with the EMG duration of the involuntary cough event within a processing device to diagnose a physiological abnormality such as a neurological deficiency within the patient.Type: ApplicationFiled: July 16, 2013Publication date: November 14, 2013Inventors: W. Robert ADDINGTON, Stuart P. MILLER, Robert E. Stephens, Michael M. PHELIPA, Mary W. BRIGANTI
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Publication number: 20130261419Abstract: A urine shield comprises an elongate base and side walls connected to the base. At least one of the sides and base is absorbent. The shield further comprises at least one attachment tab for releasably attaching the shield to a user's skin The shield has an hourglass shaped cross-section. A method and device for the collection of a urine sample from an individual is also provided.Type: ApplicationFiled: November 25, 2011Publication date: October 3, 2013Inventor: Angela Davidson
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Publication number: 20130131480Abstract: Body fluid testing device for analyzing a body fluid comprises a test media tape adapted to collect the body fluid. The test media tape comprises a tape and test media portions. A free tape portion without test medium is located between successive test media portions. The testing device further comprises a supply portion. The supply portion comprises a housing in which uncontaminated test media tape is contained. The housing further has an opening for withdrawing test media tape from the housing. The testing device further has a sealing means for closing the opening against the surrounding. A free tape portion of the test media tape is located between a wall of the housing and the sealing means when the sealing means closes the opening. Further aspects concern a test media cassette with sealing means and a method for providing test media while holding them sealed against humidity during onboard storage.Type: ApplicationFiled: January 17, 2013Publication date: May 23, 2013Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventor: ROCHE DIAGNOSTICS OPERATIONS, INC.
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Publication number: 20130131479Abstract: A composite diagnostic system comprising a support member having a membrane penetration element; a bodily fluid collection point positioned for collection of a bodily fluid released by application of the membrane penetration element to a user's body; a test material positioned in the support member such that in use the bodily fluid is brought into contact with the test material.Type: ApplicationFiled: March 18, 2011Publication date: May 23, 2013Inventors: John Michael Kelly, Eric Siu, Alison Ruth Norcott, Christopher David Dunn, Ian Frederick Johnson, Ernesto Monis Hueso, Richard Sokolov
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Publication number: 20130060114Abstract: A test element comprises a puncture element and a test pane. The puncture element has a tip for generating a wound and a capillary structure. The capillary structure extends from the tip to the test panel and has a fluid connection to the tip configured to allow body fluid to penetrate into the capillary structure. The test panel contains at least a part of the reagent system and is positioned in the test element adjacent to a part of the capillary structure of the puncture element in such a manner that body fluid penetrating into the capillary structure contacts a liquid entry side of the test panel. The test panel comprises a transparent support layer and a test layer applied to the support layer by coating, the side of the test panel facing away from the support layer forming its liquid entry side, which faces toward the capillary structure.Type: ApplicationFiled: January 17, 2012Publication date: March 7, 2013Inventors: Hans-Peter Haar, Joachim Hoenes
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Publication number: 20120316415Abstract: An apparatus comprises a detection indicator, a housing, and an exoskeleton in which the housing nests. The detection indicator is configured to furnish a visual indication upon contact with a fluid responsive to a characteristic of the fluid. The housing comprises an interior chamber configured to receive the fluid and to provide contact between the fluid and the detection indicator. The housing is configured to removably engage a conduit coupled to a source of a fluid sample, which may be a lumen inserted into a patient to receive fluid therefrom. In methods for use with the apparatus, a sample is collected, a characteristic is measured by the apparatus, and the apparatus is disconnected so as to avoid leakage of the sample and exposure of personnel.Type: ApplicationFiled: August 20, 2012Publication date: December 13, 2012Inventor: Paul J Gilbert
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Publication number: 20110077495Abstract: An apparatus comprises a detection indicator and a housing. The detection indicator is configured to change from a first visual indication to a second visual indication upon contact with a fluid based on a characteristic of the fluid. The housing comprises an interior chamber configured to receive the fluid and to provide contact between the fluid and the detection indicator. The housing is configured to removably engage a lumen inserted into a patient to receive the fluid from the patient through the lumen.Type: ApplicationFiled: October 29, 2010Publication date: March 31, 2011Inventor: Paul J. Gilbert
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Patent number: 7758505Abstract: A method and apparatus are presented for non-invasive determination of blood clotting related and blood circulation related parameters of a mammal. At least one stimulus ST is non-invasively induced in a blood containing medium in the mammal for a preset period of time tST. This at least one stimulus is selected to cause at least one of the following to occur: (a) inducing at least two of three Virchow's triad elements including abnormalities of blood flow; abnormalities of blood constituents and abnormalities of the blood vessel wall, and (b) inducing a change in red blood cell (RBC) aggregation or local blood viscosity. Measurements are non-invasively performed at a measurement location in the mammal by applying an external field thereto for a preset time period tm, a response of the measurement location to the applied field is detected, and measured data indicative thereof generated.Type: GrantFiled: November 27, 2006Date of Patent: July 20, 2010Assignee: ELFI-Tech Ltd.Inventors: Ilya Fine, Leonid Shvartsman
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Publication number: 20030109777Abstract: A body fluid testing device includes a body member and a tissue penetrator carried by the body member. A test strip holder is carried by the body member, and a test strip is carried by the test strip holder. The test strip is capable of receiving a body fluid thereon and processing the body fluid into a form suitable for yielding test results relating to the content of the body fluid.Type: ApplicationFiled: December 6, 2002Publication date: June 12, 2003Inventors: Hans G. Kloepfer, Reinhard Hafellner, Charles W. Roach, Charles Thomeczek
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Patent number: 6503198Abstract: The present invention relates to noninvasive transdermal systems and methods for analyte extraction from a biological fluid within or beneath the skin, such as interstitial fluid, and detection of the analyte. More particularly, the present invention relates to noninvasive transdermal patches comprised of a wet chemistry component and a dry chemistry component. The wet chemistry component is a liquid transfer medium in the form of a gel layer for the extraction and liquid bridge transfer of the analyte of interest from the biological fluid within or beneath the skin to the dry chemistry component. The dry chemistry component is a super sensitive or conditioned membrane carrying a reagent system for interacting with the analyte of interest to generate an indicator molecule, e.g., color change, to confirm detection of the analyte, and methods of use thereof.Type: GrantFiled: September 11, 1997Date of Patent: January 7, 2003Inventors: Jack L. Aronowtiz, Joel R. Mitchen
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Patent number: 6432052Abstract: A health examination card and its explainer wherein the health examination card can be used to test the biochemical items of blood (BLD), bilirubin (BIL), urobilinogen (URO), protein (PRO), nitrite (NIT), glucose (GLU), free calcium (Ca), etc and the card explainer can be used to analyze the test results of the above items so as to inspect the health status and provide the early indication of the diseases for finding diseases early. Besides, said examination card and its explainer is easy to use.Type: GrantFiled: March 29, 2000Date of Patent: August 13, 2002Inventors: Chongde Yao, Weimin Peng, Zhong Li
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Publication number: 20010053876Abstract: An article for the identification of the premature rupture of a membrane during pregnancy is disclosed. In its preferred embodiment, the article comprises a pad having an upper outer layer, a lower outer layer, and an intermediate pH-responsive component. A double-sided adhesive strip is attached to the lower outer layer. The upper outer layer is composed of a liquid permeable material. Intermediate of the upper out layer and the inner outer layer is a pH-sensitive component. This intermediate layer is a pH-sensitive material and may be one of a variety of such materials, although a preferred material is nitrazine paper. In the presence of an alkaline fluid, such as amniotic fluid, the pH-sensitive material responds by turning to a purple-blue color. The change in color acts as a visual indicator to the wearer of the possible presence of amniotic fluid outside of the amniotic sac.Type: ApplicationFiled: February 26, 2001Publication date: December 20, 2001Inventors: Brian A. Torok, Ramada S. Smith
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Publication number: 20010025140Abstract: An article for the identification of the premature rupture of a membrane during pregnancy is disclosed. In its preferred embodiment, the article comprises a pad having an upper outer layer, a lower outer layer, and an intermediate pH-responsive component. A double-sided adhesive strip is attached to the lower outer layer. The upper outer layer is composed of a liquid permeable material. Intermediate of the upper out layer and the inner outer layer is a pH-sensitive component. This intermediate layer is a pH-sensitive material and may be one of a variety of such materials, although a preferred material is nitrazine paper. In the presence of an alkaline fluid, such as amniotic fluid, the pH-sensitive material responds by turning to a purple-blue color. The change in color acts as a visual indicator to the wearer of the possible presence of amniotic fluid outside of the amniotic sac.Type: ApplicationFiled: January 12, 2001Publication date: September 27, 2001Inventors: Brian A. Torok, Ramada S. Smith, Valerie Montgomery-Rice
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Patent number: 6149590Abstract: An article for the identification of the premature rupture of a membrane during pregnancy is disclosed. In its preferred embodiment, the article comprises a pad having an upper outer layer, a lower outer layer, and an intermediate pH-responsive component. A double-sided adhesive strip is attached to the lower outer layer. The upper outer layer is composed of a liquid permeable material. Intermediate of the upper out layer and the inner outer layer is a pH-sensitive component. This intermediate layer is a pH-sensitive material and may be one of a variety of such materials, although a preferred material is nitrazine paper. In the presence of an alkaline fluid, such as amniotic fluid, the pH-sensitive material responds by turning to a purple-blue color. The change in color acts as a visual indicator to the wearer of the possible presence of amniotic fluid outside of the amniotic sac.Type: GrantFiled: July 13, 1999Date of Patent: November 21, 2000Inventors: Ramada S. Smith, Brian A. Torok
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Patent number: 6126597Abstract: An article for the identification of the premature rupture of a membrane during pregnancy is disclosed. The article comprises a pad having an upper outer layer, a lower outer layer, and an intermediate pH-responsive component. A double-sided adhesive strip is attached to the lower outer layer. The upper outer layer is composed of a liquid permeable material. Intermediate of the upper out layer and the inner outer layer is a pH-sensitive component. This intermediate layer is a pH-sensitive material and may be one of a variety of such materials, although a preferred material is nitrazine paper. In the presence of an alkaline fluid, such as amniotic fluid, the pH-sensitive material responds by turning to a purple-blue color. The change in color acts as a visual indicator to the wearer of the possible presence of amniotic fluid outside of the amniotic sac.Type: GrantFiled: July 22, 1998Date of Patent: October 3, 2000Inventors: Ramada S. Smith, Brian A. Torok
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Patent number: 6042543Abstract: A device and method for determining the concentration of an analyte, particularly a chloride ion, in a liquid sample are particularly useful to screen for cystic fibrosis in an individual. In a preferred embodiment, the device takes the form of a patch comprising an absorbent material sandwiched between two liquid-impermeable layers. Chloride ions in the liquid sample complex with a chloride-detecting agent dispersed throughout the absorbent material to form a visible precipitate, preferably silver chloride. A pH indicator is also dispersed throughout the absorbent material, allowing the position of the water front to be monitored thereby permitting calculation of chloride concentration from a partially filled patch.Type: GrantFiled: October 14, 1997Date of Patent: March 28, 2000Assignee: Regents of the University of MinnesotaInventors: Warren J. Warwick, Leland G. Hansen
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Patent number: 5823953Abstract: A method and device for distinguishing between yeast infection and other secretion-causing conditions makes use of the observation that secretions caused by yeast infection generally have a pH of less than about 4.5, whereas most other conditions cause less acid secretions. The device is for use by the woman having the secretions and does not involve introducing anything into the body nor does it require special skills or training. A material that indicates pH by a color change is mounted on a catamenial pad, pantyliner or the like worn on the body so as to be wetted by the secretions draining from the vagina. Observation of the color of the wetted material enables the user, by simple comparison to a color chart, to determine whether she has a yeast infection that is treatable by medicine available without medical prescription or whether she should instead see a physician because yeast treatment would be ineffectual and would delay proper treatment.Type: GrantFiled: June 20, 1996Date of Patent: October 20, 1998Inventors: Amy C. Roskin, Joanne M. Richards
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Patent number: 5823954Abstract: A disposable device for analysis or detection of a component, or of a biological or biochemical state of a body fluid present in an elongate intracorporeal cavity. The disposable device includes an elongate sampling element that is adapted to be fitted and held by simple constriction of the intracorporeal cavity. The elongate sampling element is inherently and sufficiently stiff or rigid along its length for it to be pushed via one end and introduced via the other end into the intracorporeal cavity. The device also includes the body fluid sampler distributed or arranged outside the elongate element and a cap having a side wall that is complementary to the elongate element and separable from the elongate element. The device also has a reaction agent distributed or arranged on the side wall of the cap that reacts in a manner perceptible or visible to the user with at least one component of the sample body fluid or in the presence of a biological or biochemical state of the fluid.Type: GrantFiled: March 11, 1997Date of Patent: October 20, 1998Inventor: Bernard Chaffringeon
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Patent number: 5817011Abstract: A dermal patch to be worn on the skin for increasing the concentration of an analyte expressed through the skin in perspiration to a conveniently measurable level. Included are patches and methods of using such patches to determine the quantity of an analyte in a given volume of perspiration, to determine a subject's sensitivity to an allergen, to allow an analyte to be detected with conventional detection systems, and to dissolve the structural components of a patch to facilitate analyte detection.Type: GrantFiled: February 3, 1997Date of Patent: October 6, 1998Assignee: Sudormed, Inc.Inventor: Donald W. Schoendorfer