Abstract: A method for making a medical electrical lead electrode assembly includes the steps of: forming an insulative carrier from an insulative material; coupling at least one conductive component to the carrier by inserting a pre-formed tab of the conductive component through the carrier, from a first side thereof to a second side thereof, so that the conductive component is secured to the carrier with the tab extending along a surface of the second side of the carrier and an inward facing surface of an electrode portion of the conductive component being disposed against a surface of the first side of the carrier; coupling an elongate flexible conductor to the tab of the component; and forming an insulative layer over the second side of the carrier, the tab and the conductor electrically coupled to the tab.

Abstract: The present invention relates to a real-time electrocardiogram monitoring system and method, a patch-type electrocardiograph and a telecommunication apparatus.

Abstract: A lead anchor includes a body defining at least one first portion of a lead lumen, the body having a first opening and a second opening. An obstructing member is disposed within the body. The obstructing member defines a second portion of the lead lumen. A spring is disposed in the body and configured and arranged to operate on the obstructing member so that the second portion of the lead lumen is coterminous with the at least one first portion of the lead lumen and forms a continuous lead path when the spring is compressed and the second portion of the lead lumen is offset from the at least one first portion of the lead lumen when the spring is not compressed.

Abstract: An adherent device comprises an adhesive patch with at least two electrodes and an accelerometer. The accelerometer can be used to determine an orientation of the at least two measurement electrodes on a patient. By determining the orientation of the electrodes of the patch on the patient, physiologic measurements with the at least two electrodes can be adjusted and/or corrected in response to the orientation of the patch on the patient. The adherent patch and/or electrodes can be replaced with a second adherent patch and/or electrodes, and the orientation of the second adherent patch and/or electrodes can be determined with the accelerometer or a second accelerometer. The determined orientation of the second patch and/or electrodes on the patient can be used to correct measurements made with the second adherent patch and/or electrodes.

Abstract: According to one aspect of the invention, there is provided an electrocardiographic monitoring system including: a housing configured to be attached to a creature body part, the housing including: a plurality of electrodes confined within the boundary of the housing, the plurality of electrodes arranged a distance apart from each other and accessible from a same exterior surface of the housing; a signal processor configured to receive signals from any one or more of the plurality of electrodes and transmit signals to any one or more of the plurality of electrodes; and a transmitter configured to transmit signals from the signal processor.

Abstract: Nanofiber adhesives and their uses with device, such as medical devices, are described. In one embodiment, a nanofiber adhesive layer may be disposed on a surface of a medical device, such as a backing layer of a sensor, for adhesion to a substrate. The nanofiber adhesive layer may allow durable adhesion to the substrate. Other described features may include materials and methods to determine the attachment of the medical device to a patient by determining the adhesive state of the adhesive layer.

Abstract: A miniature microdrive system may be affixed to the skull and used to advance recording electrode bundles or injection cannula through the brain of freely moving test subjects, e.g., rodents. The microdrive may be constructed using a hybrid fabrication technique utilizing a printed circuit board and a small number of mechanical parts. The printed circuit board provides the base for both the electrical components and the mechanical components. The movement of a screw advances a shuttle that in turn moves an electrode bundle through the brain. Independently moving screws advance independent electrode bundles. The electrode wires are connected through the printed circuit board to a connector on the back of the board. Stainless steel cannulae are soldered to a grounding trace on the printed circuit board to guide the electrode bundle and provide a ground connection. With this system, multiple brain structures may be targeted simultaneously.

Abstract: Embodiments relate to methods and systems for monitoring bioelectric potentials. In some instances, an electrode is applied to a patient's skin. The electrode may be at least partly inserted into the patient's skin, such as by inserting at least part of one or more teeth underneath the skin.

Abstract: An electrical capacitance tomography sensor comprised of a sensor having a plurality of electrodes, where each electrode is further comprised of a plurality of capacitance segments. Each of the capacitance segments of each electrode can be individually addressed to focus the electric field intensity or sensitivity to desired regions of the electrodes and the sensor.

Abstract: An assembly for reducing motion artifacts that includes an opening on the face of the assembly, an elastic material at least partially covering the opening for suspending objects above the opening, and a sensor attached to the elastic material wherein the sensor is suspended over the opening so that the sensor may be moved in the direction of the opening so that it at least partially recesses into the opening when the sensor is positioned against a subject. The tension on the elastic material generates a force on the sensor directed towards the subject as the elastic material is stretched. Methods and systems of reducing motion artifacts including methods and systems using the assembly are also claimed.

Abstract: A biosensor is described which can obtain physiological data from an individual. The biosensor may collect electrodermal activity, skin temperature, and other information. The biosensor may be attached to the body through the use of a garment which may be fastened in multiple locations on the human body. The biosensor includes compensation for electrodermal activity measurements based on the amount of pressure applied to the electrodes that are in contact with the skin. As pressure is increased the electrodermal activity values typically increase. By compensating for the influence that pressure changes have on electrodermal activity, more accurate analysis of physiology and therefore mental state analysis may be performed.

Abstract: A sensor for measuring a physiological signal and a method for manufacturing such a sensor. Such a sensor includes a flexible substrate and at least one electrode, which has a signalling surface, which faces in the same direction as the first surface of the flexible substrate. In addition, the sensor includes a signal transmission conductor, which is connected electrically to the electrode. The signal transmission conductor is attached in a watertight manner to the second surface of the substrate. The sensor is reliable, economical to manufacture, and comfortable to the user.

Abstract: A portable medical device has a medical measuring apparatus and an elastic mounting portion. The medical measuring apparatus has a body. The body has a mounting mechanism. The elastic mounting portion is arched, adapted to be mounted around a subject's wrist or arm and has two edges and an attaching mechanism. The two edges are opposite to each other and define a gap for placement of the subject's wrist or arm. The attaching mechanism detachably engages the mounting mechanism of the body of the medical measuring apparatus. Thus the portable medical device is convenient for daily use and for carrying on a subject by simply mounting around the subject's wrist or arm by the elastic mounting portion.

Abstract: A system for a disposable capacitive bioimpedance sensor is used to collect bioimpedance data from an electric current traveling into or through an organism's tissue, where the bioimpedance data can be used to make medical analysis. The system mainly comprises at least one disposable sensor, at least one communication channel, a sensing circuit, and an instrument portion. The disposable sensor and the sensing circuit are used to retrieve the bioimpedance data from the organism's tissue, which is then sent to the instrument portion through the communication channel in order to be analyzed and processed. The disposable sensor includes a plurality of electrodes, an electrode support layer, and a capacitive signal receptor. The electrodes deliver the electrical current to the organism's tissue, and the capacitive signal receptor allows the electrical current to be properly sent or received through the organism's tissue. The electrode support layer holds the electrodes in place.

Abstract: The present invention relates to a device for securing medical leads in a cranial burr hole, in particular, for securing a brain stimulation lead within such a burr hole. The device includes a circular socket element adapted to be secured within a burr hole of the skull of a patient, the circular socket element having a through lead passage arranged to have the lead pass therethrough, the lead passage including passage walls including at least one resilient partition wall extending from an inner wall of the circular socket element, and the circular socket element having at least one inner compartment delimited by the partition wall.

Abstract: Provided herein are skin-mounted biomedical devices and methods of making and using biomedical devices for sensing and actuation applications. For example, flexible and/or stretchable biomedical devices are provided, including electronic devices useful for establishing conformal contact with the skin of a subject. Devices disclosed herein can comprise a plurality of sensing and/or actuating devices provided as part of a skin-mounted flexible or stretchable electronic circuit.

Abstract: An apparatus including a chest strip including a plurality of precordial leads positioned to correspond with desired lead placement for an electrocardiogram; and a plurality of limb leads coupled to the chest strip. A system including a chest strip including a plurality of precordial leads positioned to correspond with desired lead placement for an electrocardiogram; a plurality of limb leads coupled to the chest strip; and a transmitter coupled to plurality of precordial leads and the plurality of limb leads to transmit signals generated by the plurality of precordial leads and the plurality of limb leads. A method including coupling a chest strip including a precordial leads to a newborn; and generating an electrocardiogram from the precordial leads.

Abstract: Disclosed herein are apparatus and techniques for applying a device to a subject. Such apparatus and techniques may provide feedback to an operator and/or regulate the force used to apply the device, yielding an improved result. Particularly useful embodiments include apparatus and techniques for applying a medical device, such as a skin surface electrode or microneedle array, to a patient's tissue.

Abstract: An ECG electrode lead system suitable for use during imaging procedures such as, without limitation, CT scans or MRI and methods of use. The a radiolucent ECG lead set cable includes at least one radiolucent conductor, at least one radiolucent electrode connector operatively coupled to a distal end of the ECG lead set cable, an ECG intermediate lead set connector disposed at a proximal end of the ECG lead set cable, and an ECG lead extension assembly.

Abstract: Apparatus and techniques are provided for interfacing a device with a surface. The apparatus and techniques provide gel encapsulation and isolation mechanisms to extend the shelf-life of the preparation devices, allow for the use of more effective materials, and improve the quality of the contact between a device and an application surface. Particular embodiments of these apparatus and techniques suitable for use in medical contexts are also provided.

Abstract: The system for displaying muscle force data includes a wearable patch and a remote visual display. The wearable patch carries electrodes suitable for sensing electromyographic signals on the skin of the patient. The patch carries circuitry which converts the detected electromyographic signal to a digital output which can be transmitted to the remote visual display. The circuitry relies on filtering to produce a usable digital signal at very low power consumption. The transmitted signal can be used to drive a variety of visual displays, including a conventional hand-held personal communicators and entertainment devices which had been programmed to suitably process the visual display.

Abstract: A medical electrical lead electrode assembly includes an insulative carrier and at least one conductive component. The at least one conductive component includes an electrode portion disposed on a first side of the carrier and at least one tab extending away from the electrode portion, through the carrier to a second side of the carrier. The electrode portion of the at least one component includes an outward facing contact surface and an inward facing surface, the inward facing surface being disposed opposite the contact surface and against a surface of the first side of the carrier. The electrode assembly further includes a joint coupling a flexible elongate conductor to the tab of the at least one component on the second side of the carrier, and an insulative layer extending over the joint and the tab and the conductor, the insulative layer being bonded to the second side of the carrier.

Abstract: Disclosed herein is a mountable unit for biological signal measurement, including: three electrodes; and a support body configured to support the three electrodes at positions corresponding to a positional relationship among a predetermined position on a forehead on one side of a face bounded by a midline, a temple position on the one side of the face, and a predetermined position on a zygomatic body on the one side of the face.

Abstract: A biosensor is described which can obtain physiological data from an individual. The biosensor may collect electrodermal activity, skin temperature, and other information. The biosensor may be attached to the body through the use of a garment which may be fastened in multiple locations on the human body. The biosensor includes compensation for electrodermal activity measurements based on the amount of pressure applied to the electrodes that are in contact with the skin. As pressure is increased the electrodermal activity values typically increase. By compensating for the influence that pressure changes have on electrodermal activity, more accurate analysis of physiology and therefore mental state analysis may be performed.

Abstract: A lead anchor includes a plurality of parallel tubular members and at least one suture element configured and arranged for receiving a suture to suture the lead anchor to patient tissue. Each tubular member defines a lead lumen having a first opening and a second opening through which a lead can pass.

Abstract: Provided is a bio-signal detection electrode including: an electrode section made of a gel including an electrolytic solution; and a support section configured to support the electrode section with respect to an accessory, the electrode section adhering to the support section.

Abstract: Embodiments relate to methods and systems for monitoring bioelectric potentials. In some instances, an electrode is applied to a patient's skin. The electrode may be at least partly inserted into the patient's skin, such as by inserting at least part of one or more teeth underneath the skin.

Abstract: An implant device comprising an electrode for electrical stimulation of the pancreas, the device being adapted to be inserted into the pancreas, and to change at least one of its properties after being inserted into the pancreas, so that it will cause less irritation to the pancreas than before changing said property.

Abstract: A self-adhering sensor for non-invasively attaching to a portion of a skin is provided. The sensor comprises a biocompatible substrate, and an array of solid nanoelectrodes coupled to the biocompatible substrate and configured to self-adhere to the skin. Also provided is a sensor for attaching to a portion of a skin, where the sensor comprises an array of solid electrodes configured to self-adhere to the skin, where each of the solid structures comprises a stem and one or more projections extending out from the stem, where both the stem and the projections are solid. The stem comprises a mechanical stopper to control the extent of penetration of the solid electrodes into the skin. The sensor further comprises an electrolyte coating disposed on one or more of the solid structures.

Abstract: A sensor array apparatus for monitoring medical signals includes a flexible substrate adapted for positioning relative to the torso of a patient. The flexible substrate includes a central segment defining a central axis and is adapted to generally conform to an area extending along the sternum of a patient. The flexible substrate further includes an upper segment extending traversal across the central segment and adapted to generally conform to the chest area of a patient and a lower segment extending traversal across the central segment and adapted to generally conform to the abdominal area of the patient. The apparatus further includes a medical electrode disposed on at least one of the segments and a connector in electrical communication with the medical electrode and adapted to connect to an electronic monitoring system.

Abstract: A dry sensor EEG/EMG and motion sensing system for seizure detection and monitoring is disclosed. In some embodiments, a system for seizure detection/monitoring is provided that can measure a user's EEG/EMG and motor activity, automatically detect an epileptic seizure and perform actions, such as triggering an alarm and/or turning off the provoking stimulation. In some embodiments, a system for seizure detection/monitoring is provided that can be used to continuously monitor and store a user's EEG/EMG and motor activity for doctor evaluation. In some embodiments, a system for seizure detection/monitoring is provided that can be mounted directly on a user's head using active dry EEG sensors. In some embodiments, a system for seizure detection/monitoring is provided that can be mounted into/onto a pair of glasses (e.g., 3D glasses), and the user's eyes can be automatically covered by the glasses if a seizure is detected.

Abstract: A lead anchor includes a body defining at least one first portion of a lead lumen, the body having a first opening and a second opening. An obstructing member is disposed within the body. The obstructing member defines a second portion of the lead lumen. A spring is disposed in the body and configured and arranged to operate on the obstructing member so that the second portion of the lead lumen is coterminous with the at least one first portion of the lead lumen and forms a continuous lead path when the spring is compressed and the second portion of the lead lumen is offset from the at least one first portion of the lead lumen when the spring is not compressed.

Abstract: Textile-based electrodes include a fabric portion having stretch-recovery non-conductive yarns and an electrically conductive region having stretch-recovery electrically conductive yarn filaments. The electrodes can further include float yarns and can be configured in a textured or ribbed construction. When incorporated into a garment, the electrodes can be used to monitor biophysical characteristics, such as the garment wearer's heart rate. In addition, two garments with textile based electrodes are disclosed. First, a wrist band for use with a cardiac patient remote monitoring system includes two fabric layers with integral textile-based electrodes. The skin contacting surface of the band includes a conductive region formed as a continuous ring or stripe. A connector links the conductive region to a lead to a device.

Abstract: A sensor measuring skin impedance includes a reference electrode, a current carrying electrode, and a measuring electrode for measuring impedance for current flowing between the reference electrode and the current carrying electrode. The measuring electrode is recessed with respect to the reference electrode and the current carrying electrode, allowing the measuring electrode to make contact with a user's skin after the reference electrode and current carrying electrode make contact, resulting in greater measurement accuracy.

Abstract: An electrically non-conductive back plate for supporting the back of a patient in a supine position comprises on its front face facing the back of the patient a pair or more of ECG electrodes capable of maintaining electrically conductive skin contact with the patient's back. The pair of ECG electrodes is disposed at a sharp angle with the mean heart vector, in particular so as to form an angle ? of about 45°±25° with the projection S of the patient's spine on the back plate. Also disclosed is an ECG electrode for mounting in a recess of the back plate and an apparatus for treating cardiac arrest by compression of the sternum comprising the back plate.

Abstract: A transdermal medicament patch includes a biocompatible substrate having a therapeutic face on one side configured for disposition against the skin of a patient, a biocompatible adhesive on the therapeutic face, a planar medicament matrix covering a portion of the therapeutic face, and a release liner covering the portion of therapeutic that is not obscured by the medicament matrix. An aperture formed through the release sheet affords direct access by medicament to the entire surface of the medicament matrix opposite from the therapeutic face of the substrate. An active electrode positioned between the medicament matrix and the therapeutic face of the substrate includes an electrically conductive backing layer positioned against the therapeutic face of the substrate and a pH-control layer covering less than all of the side of the backing layer opposite from the therapeutic face of the substrate.

Abstract: Embodiments relate to methods and systems for monitoring bioelectric potentials. In some instances, an electrode is applied to a patient's skin. The electrode may be at least partly inserted into the patient's skin, such as by inserting at least part of one or more teeth underneath the skin.

Abstract: A non-intrusive wearable respiratory failure alarm apparatus and method capable of detecting a user's respiratory failure state by estimating a change in a user's respiratory rate, while minimizing restrictions on a user's behavior are provided. The non-intrusive wearable respiratory failure alarm apparatus includes: a chest girth measurement unit including one or more resistive electro-threads attached to or worn on a user's chest, and generating a resistance value corresponding to the user's chest girth through the resistive electro-threads; a signal processing unit calculating a user's respiratory rate and whether or not the user is in respiratory failure by referring to the resistance value; and an output unit providing information regarding the user's respiratory rate and/or information regarding whether or not the user is in respiratory failure to the user or a monitoring device.

Abstract: Embodiments relate to methods and systems for monitoring bioelectric potentials. In some instances, an electrode is applied to a patient's skin. The electrode may be at least partly inserted into the patient's skin, such as by inserting at least part of one or more teeth underneath the skin.

Abstract: An ECG lead set including an ECG electrode assembly and a lead set hub. ECG electrode includes at least one electrode configured to receive biopotential signals from a patient, a plug connector for connecting said ECG electrode assembly, a web, connected between the at least one electrode and the plug connector and configured to form an electrical connection therebetween. The lead set hub includes at least one receptacle configured to receive the plug connector of the ECG electrode assembly.

Abstract: A textile structure for detecting body surface electrical signals of human is provided. The textile structure includes a non-conductive textile, a conductive textile, and a plurality of test terminals. The non-conductive textile covers the human body. The conductive textile has a first region, a second region, and a third region. The first region is interdigitated into but not electrically coupled to the third region. The first to third test terminals are respectively coupled to the first to third regions of the conductive textile. The first and second test terminals are used for detecting ECG signals. The first and third test terminals are used for detecting respiratory signals.

Abstract: The present invention concerns a device and a method for placing and securing sensors/electrodes on the head of an individual. The device/method optimizes signal information and avoids some of the problems connected to the devices and methods in the prior art. The device comprises a rigid, fluid-proof outer layer, an elastic, fluid-proof inner layer with placement points for sensors or electrodes, and a middle layer comprising a fluid between inner and outer layers. The invention also comprises a device for regulating the pressure of the fluid. Inner and outer layers are joined together to form a cavity for receipt of the middle layer.

Abstract: Embodiments relate to methods and systems for monitoring bioelectric potentials. In some instances, an electrode is applied to a patient's skin. The electrode may be at least partly inserted into the patient's skin, such as by inserting at least part of one or more teeth underneath the skin.

Abstract: Electrode plate comprising a stiff or flexible electrically non-conductive plate element having a front face and a rear face and a pattern of needle-like (NL) electrodes for electrical stimulation of cutaneous thin A?/C fibers and conductive plate (CP) electrodes for electrical stimulation cutaneous large A? fibers disposed on the front face.

Abstract: An embodiment of the invention includes a biocompatible stiffness enhanced pliable electrically conductive filament configured for contact with living tissue and electrical communication with such tissue. The pliability of the filament allows the distal end of the filament to remain at the original site of penetration into the tissue despite the movement of the tissue relative to its surrounding environment. To temporarily stiffen the filament, a soluble stiffness enhancing coating is disposed over the filament. The coating may be in the form of a liquid which dries to a solid state after being applied to the filament and renders the filament sufficiently rigid such that under appropriate force, the filament is capable of penetrating into dense tissue. Once in place the stiffness enhancing coating dissolves due to contact with body fluids, the filament, in the absence of such coating, returns to its initial pliability.

Abstract: The invention relates to an electrode arrangement and a measuring device for measuring the action flow and/or the action potential of an electrically active tissue. The aim of the invention is to provide a simple and economically producible electrode for measuring action flows and/or action potentials in electrically active tissues (preferably the stapedius muscle tissue), ensuring that the electrode is fixed securely, but reversibly, in the muscle tissue and that the muscle tissue is disturbed as little as possible. The electrode arrangement according to the invention comprises a first electrode (2) and a fixing element (3), the first electrode (2) being connected to a first, long electrical line (4) and consisting of a long base body (6) comprising a first end (7) and a second end (8). The first electrical line (4) is connected to the base body (6) in the region of the second end (8) thereof, and means are provided for reversibly fixing the fixing element (3) to the first electrode (2).

Abstract: A living body data detector equipped with a fitting belt which does not deviate in position, does not fall down and does not press the chest even when taking exercise while fitting it on is provided. A living body data detector comprises a fitting belt having a pair of shoulder belt portions that is, a left shoulder belt portion and a right shoulder belt portion, a pair of electrode portions attached to the fitting belt, and a living body signal detector portion connected to the pair of electrode portions through connection cables, and attached to the fitting belt. The left shoulder belt portion and the right shoulder belt portion are forming an intersected coupling portion on the back side of the user. A living body signal detector portion is attached to the intersected coupling portion. The left shoulder belt portion is provided with an expansion portion and a separable coupling means, and the right shoulder belt portion is provided with an expansion portion and a separable coupling means.

Abstract: The present invention relates to sensory for measuring signals on the surface of the skin and for producing sensory. In the sensory in accordance with the invention, the electrode surfaces required for measuring of a signal and/or conductors required for transmitting of a signal have been fastened to the textile material of an outfit or accessory used on the body. In the method in accordance with the invention, the electrode surfaces required for the sensory and/or conductors are added to the textile material of an outfit or accessory used on the body.

Abstract: The present invention relates to an electrode harness and more particularly to an electrode harness with various features, which enhance the use and performance of the electrode harness. The present invention further relates to a method of taking biopotential measurements. The electrode harness and methods of the present invention allow for use with most applications where biopotential measurements are taken. The electrode harness can be used in ECG (or EKG), EEG, EMG, and other such biopotential measurement applications. Because of the versatility of various embodiments of the present invention, preferably the electrode harness can be adjusted for different applications or for application to various sized and shaped subjects. The electrode harness is further preferably part of a system, which includes either wireless or tethered bridges between the electrode harness and a monitor, and preferably includes various forms of processors for analyzing the biopotential signal.

Abstract: A stretchable electrode for use in physiologic measurements on a human body, such as peripheral impedance plethysmography, is disclosed. One embodiment of the stretchable electrode comprises an uninsulated stainless steel wire braid formed into a tubular conductor surrounding an elastic core and attached to an elastic substrate or base. Other embodiments of the stretchable electrode include a garter spring, a flat braided or woven conductor and an undulating wire. The electrode is placed about a limb of a human body and elastically stretched so that the conductor is in substantially continuous circumferential electrical contact with the skin of the limb. A method of attaching the stretchable electrode to the limb of a human body is also disclosed.