Magnetic Field Sensor (e.g., Magnetometer, Squid) Patents (Class 600/409)
  • Patent number: 10349870
    Abstract: Methods of exerting magnetic forces to collect and manipulate magnetic particles disposed in a portion of subsurface vasculature using a wearable device are provided. The wearable device is configured to change the exerted magnetic force over time. For example, the exerted magnetic force could be sufficient to collect the magnetic particles during a first period of time and low enough to release the magnetic particles during a second period of time. The exerted magnetic force could be changed over time to vary some effect on the magnetic particles, for example to control a rate of release of collected magnetic particles. In some embodiments, the magnetic particles are configured to bind to an analyte of interest. The collection and manipulation of the magnetic particles can enable detection of one or more properties of the analyte, modification of the analyte, and/or extraction of the analyte bound to the magnetic particles.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: July 16, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Vasiliki Demas, Vikram Singh Bajaj
  • Patent number: 10314520
    Abstract: A system and method for collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user; segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal characterize a biomechanical property during a segment and includes generating a first integration data set through data integration and baseline error correction across the set of segments of the normalized kinematic data stream and determining at least a first biomechanical signal that is at least partially based on the first integration data set; and applying the set of biomechanical signals.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: June 11, 2019
    Assignee: SEISMIC HOLDINGS, INC.
    Inventors: Andreas Martin Hauenstein, Ray Franklin Cowan, Andrew Robert Chang
  • Patent number: 10271795
    Abstract: A catheter assembly including one or more conductive pathways is disclosed. The conductive pathways assist with initial placement of the catheter assembly into a patient's vasculature by enabling ECG signals emanating from the patient's heart to be detected. In addition, the conductive pathways are configured to be used to reconfirm via ECG signal detection proper placement of the catheter assembly at a time subsequent to initial catheter placement into the vasculature. In one embodiment, therefore, a catheter assembly is disclosed, comprising an elongate catheter tube defining at least one lumen, a first conductive pathway extending distally from a proximal point on the catheter assembly to a predetermined distal location on the catheter tube, and a second conductive pathway at least partially disposed on an outer surface of the catheter tube and extending distally from a proximal point of the catheter assembly to a predetermined distal location on the catheter tube.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: April 30, 2019
    Assignee: C. R. Bard, Inc.
    Inventor: Dennis L. Salzmann
  • Patent number: 10238349
    Abstract: An imaging apparatus for diagnosis comprises a display unit configured to display a longitudinal-sectional image in a first display area, and display a cross-sectional image corresponding to an arbitrary position in an axial direction in the longitudinal-sectional image in a second display area; a signal processing unit divides the second display area into at least two individual areas in case of accepting an instruction to the effect that a predetermined operation is executed with respect to the first display area; and the signal processing unit displays indicators in the first display area, wherein in a case in which the second display area is divided into at least two individual areas, cross-sectional images corresponding to the axial direction position are displayed by at least two indicators in respective individual areas.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: March 26, 2019
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Junya Furuichi, Naoya Iwata
  • Patent number: 10197518
    Abstract: Methods, devices and systems for three-dimensional location of the disposition of a sensor coil in a subject including are disclosed. The systems include an array of three or more triplet or quadruplet drive coil sets, at least one moveable sensor coil configured to be disposed in a subject and to provide one or more sensor coil response signals responsive to the respective electromagnetic wave fields, a receiving component configured to control drive signals to the array of drive coil sets and to measure sensor coil response signals from the moveable sensor coil, and a processor is configured to determine a sensor coil disposition in the subject relative to said triplet or quadruplet drive coil sets. The receiving component provides a modified drive signal to maximize or optimize the generated respective electromagnetic wave fields, or the one or more sensor coil response signals.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 5, 2019
    Assignee: TELEFLEX MEDICAL DEVICES S.À R.L.
    Inventors: Peter E. Nelson, Robert D. Zellers, Charles W. Henry
  • Patent number: 10159536
    Abstract: A method, a non-transitory computer readable medium, and an apparatus for operating the robotic control system comprising a master apparatus (64) in communication with an input device (58, 60) having a handle (102) and a slave system (54, 74) having a tool (66, 67) having an end effector (73) whose position and orientation is determined in response to a current position and current orientation of the handle. The method involves producing a desired end effector position and orientation in response to a current position and orientation of the handle. The method involves causing the input device to provide haptic feedback that impedes translational movement of the handle, while permitting rotational movement of the handle and preventing movement of the end effector, when a rotational alignment difference between the handle and the end effector meets a disablement criterion.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: December 25, 2018
    Assignee: Titan Medical Inc.
    Inventors: Joseph Kralicky, Peter Cameron, Rene Robert
  • Patent number: 10159531
    Abstract: Devices and systems for navigation and positioning a central venous catheter within a patient. In an exemplary embodiment of a system of the present disclosure, the system comprises a first pole and a second pole, the first pole and the second pole configured to generate an electric field within a mammalian body sufficient to obtain a plurality of field measurements therein, and an elongated body configured for at least partial insertion into a blood vessel of the mammalian body and advancement through a vasculature, said advancement dependent upon the plurality of field measurements indicative of one or more locations of a portion of the elongated body within the vasculature. In at least one embodiment, the elongated body is configured as a stylet. In another embodiment, techniques for identifying and locating obstructions in the vessel in which a device is disposed are disclosed.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: December 25, 2018
    Assignee: C. R. Bard, Inc.
    Inventors: Anthony K. Misener, Paul D. Morgan, William R. McLaughlin, Ghassan S. Kassab, William Combs, Mark Svendsen, H. Toby Markowitz
  • Patent number: 10119928
    Abstract: Methods, devices and systems for three-dimensional location of the disposition of a sensor coil in a subject including are disclosed. The systems include an array of three or more triplet or quadruplet drive coil sets, at least one moveable sensor coil configured to be disposed in a subject and to provide one or more sensor coil response signals responsive to the respective electromagnetic wave fields, a receiving component configured to control drive signals to the array of drive coil sets and to measure sensor coil response signals from the moveable sensor coil, and a processor is configured to determine a sensor coil disposition in the subject relative to said triplet or quadruplet drive coil sets. The receiving component provides a modified drive signal to maximize or optimize the generated respective electromagnetic wave fields, or the one or more sensor coil response signals.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: November 6, 2018
    Assignee: TELEFLEX MEDICAL DEVICES S.À R.L.
    Inventors: Peter E. Nelson, Robert D. Zellers, Charles W. Henry
  • Patent number: 10028674
    Abstract: Provided are ultra-low-field nuclear-magnetic-resonance myocardial electrical activity detection method and an ultra-low-field nuclear-magnetic-resonance device. The ultra-low-field nuclear-magnetic-resonance device includes magnetic shielding room; a high-sensitivity magnetic field sensor disposed adjacent to a measurement target disposed inside the magnetic shielding room; and a bias magnetic field generating coil for providing an external measurement bias magnetic field, corresponding to a proton magnetic resonance frequency (nuclear magnetic resonance frequency) corresponding to a frequency of periodic myocardial activity of a lesion desired to be measured, to the measurement target. The high-sensitivity magnetic field sensor measures a magnetic resonance signal generated from the measurement target.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: July 24, 2018
    Assignee: Korea Research Institute of Standards and Science
    Inventors: Kiwoong Kim, Yong-Ho Lee, Jin-Mok Kim, Hyukchan Kwon, Kwon Kyu Yu
  • Patent number: 9999380
    Abstract: A variety of wearable magnetic assemblies are provided that are configured to produce magnetic fields having high field magnitudes and/or high field gradients. Such magnetic assemblies include a plurality of magnetic segments arranged in a linear array. Individual magnetic segments of the magnetic array can each include multiple magnetic elements. An individual magnetic segment can include elements that have similar shape, size, composition, and relative location to elements of neighboring magnetic segments while having magnetic moments that are antiparallel to the magnetic moments of corresponding elements of the neighboring magnetic segments. These wearable magnetic assemblies are configured to exert forces on magnetic particles disposed in a portion of subsurface vasculature to attract, slow, speed, separate, or otherwise influence the magnetic particles in various applications. The magnetic particles can be configured to bind to an analyte of interest.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: June 19, 2018
    Assignee: Verily Life Sciences LLC
    Inventors: Vasiliki Demas, Vikram Singh Bajaj
  • Patent number: 9981564
    Abstract: A foreign object detector includes a plurality of first coils and a plurality of second coils. The plurality of first coils are arranged along an upper surface of a power transmission coil. The plurality of second coils are provided to correspond to the plurality of first coils, with the second coils each being arranged to face a corresponding one of the first coils. An outer shape of each of the plurality of first coils and each of the plurality of second coils is smaller than an outer shape of the power transmission coil when the power transmission coil is viewed two-dimensionally from above the power transmission coil.
    Type: Grant
    Filed: June 11, 2015
    Date of Patent: May 29, 2018
    Assignees: TOYOTA JIDOSHA KABUSHIKI KAISHA, KOJIMA INDUSTRIES CORPORATION, YAZAKI CORPORATION
    Inventors: Toru Nakamura, Hideaki Yamada, Makoto Kawaide, Satoru Horiuchi, Hiroaki Saito
  • Patent number: 9928597
    Abstract: There are provided an image processing apparatus, an image processing method and an image processing program which can easily and accurately specify and analyze an abnormal part of a subject. An image processing apparatus 100 used to specify the abnormal part of the subject includes a calculation unit 130 calculating position adjustment data between contour data of a specific subject extracted from an X-ray radiographic image and contour data of a photographic image obtained by photographing the specific subject, a sectional image generation unit 140 generating a sectional image of a three-dimensional X-ray CT image correlated with the X-ray radiographic image on a plane parallel with a light receiving face of a two-dimensional biolight image correlated with the photographic image, and a display processing unit 150 displaying the three-dimensional X-ray CT image and the two-dimensional biolight image in superposition on the sectional image, using the calculated position adjustment data.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: March 27, 2018
    Assignee: RIGAKU CORPORATION
    Inventors: Yukihiro Hara, Takafumi Koike, Minoru Maesawa
  • Patent number: 9913605
    Abstract: Systems and methods for autonomous intravenous needle insertion are disclosed herein. In an embodiment, a system for autonomous intravenous insertion include a robot arm, one or more sensors pivotally attached to the robot arm for gathering information about potential insertion sites in a subject arm, a medical device pivotally attached to the robot arm, and a controller in communication with the sensors and the robot arm, wherein the controller receives the information from the sensors about potential insertion sites, and the controller selects a target insertion site and directs the robot arm to insert the medical device into the target insertion site.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: March 13, 2018
    Assignee: Veebot Systems, Inc.
    Inventors: Richard J. Harris, Joseph B. Mygatt, Stuart I. Harris
  • Patent number: 9913589
    Abstract: Disclosed are devices, a systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various locations within the associated chamber of the heart.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: March 13, 2018
    Inventor: Christoph Scharf
  • Patent number: 9901280
    Abstract: A measuring method and apparatus in which a measurable object (23) is irradiated with acoustic waves to measure a change in property value of charged particles in the object from electromagnetic waves induced thereby. A part (2) of the measurable object irradiated with an acoustic focused beam (1) is in a charge distribution state in which positive charged particles (3) are greater in number in the part (2) where electromagnetic waves induced by positive charged particles (3) are not canceled by those induced by negative charged particles (4) and where net electromagnetic waves (6) are induced. Since a change in concentration of positive charged particles (3) and/or negative charged particles (4) changes the intensity of electromagnetic waves (6), it is possible to know such a change in concentration of the charged particles from a change in intensity of electromagnetic waves (6).
    Type: Grant
    Filed: August 14, 2006
    Date of Patent: February 27, 2018
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Kenji Ikushima, Susumu Komiyama
  • Patent number: 9877679
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: January 30, 2018
    Assignee: Great Lakes NeuroTechnologies Inc.
    Inventor: Joseph Giuffrida
  • Patent number: 9861283
    Abstract: The present invention relates to a movement disorder monitor, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides remote access to the clinician or physician.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: January 9, 2018
    Assignee: Great Lakes NeuroTechnologies Inc
    Inventor: Joseph Giuffrida
  • Patent number: 9804125
    Abstract: Invention, relates to the field of supersensitive biomagnetometry under presence of external electromagnetic interferences. In order to perform passive compensation of said interferences, design of device at the magnetometer input is proposed, comprising compensation elements and means for their moving including shifting, holding, and fixation units. In the basic embodiment, three short-closed wire contours are used which are orthogonally placed in space and independently moved up-down relative to the magnetometer or its input antenna. Contours are fixed in positions where minimum of external interference amplitude is achieved according to given field projection. Variants are proposed with cooling of meter and/or contours, location of contours inside the cryostat and their manufacturing from superconductors.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: October 31, 2017
    Inventors: Volodymyr Mykolaiovych Sosnytskyy, Yurii Dmytrovych Minov, Mykola Mykolaiovych Budnyk
  • Patent number: 9689932
    Abstract: The present invention relates to an apparatus and a method for influencing and/or detecting magnetic particles in a field of view (28), in particular for examination of human patients.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: June 27, 2017
    Assignee: Koninklijke Philips N.V.
    Inventors: Claas Bontus, Ingo Schmale, Bernhard Gleich
  • Patent number: 9684069
    Abstract: A ground-penetrating radar system or other low-frequency radar system that operates at a wavelength that is comparable to or larger than the dimensions of the transmitting and receiving antennas. In one embodiment, a radar transmitter includes two drive coils, misaligned with respect to each other, that produce respective field patterns, each modulated with a respective modulation. A radar receiver includes a composite sense coil that senses the effect a target has on the fields, and generates a corresponding signal that carries the two modulations. From the proportion of the two modulations in the received signal, which depends on the extent to which the target is in each of the two field patterns, the receiver estimates the angle (e.g., the azimuth angle) to the target. An additional measurement of the angle may be made by comparing the phases of the carrier in the two received modulations.
    Type: Grant
    Filed: January 8, 2015
    Date of Patent: June 20, 2017
    Assignee: RAYTHEON COMPANY
    Inventor: Benjamin Dolgin
  • Patent number: 9675273
    Abstract: The present invention involves a computer-based system and method for detecting and identifying implantable medical devices (“IMDs”) and/or retained foreign objects (“RFSOs”) from diagnostic medical images. In some embodiments, the system provides further identification—information on the particular IMD or RSFO that has been recognized. For example, the system may be configures to provide information feedback regarding the IMD, such as detailed manual information, safety alerts, recall, access to its structural integrity, and/or suggested courses of action in a specific clinical setting/troubleshooting. Embodiments are contemplated in which the system is configured to report possible 3D locations of RSFOs in the surgical field/images.
    Type: Grant
    Filed: April 17, 2016
    Date of Patent: June 13, 2017
    Assignee: Rush University Medical Center
    Inventor: Vicko Gluncic
  • Patent number: 9649155
    Abstract: A medical device is provided comprising a shaft comprising a first segment and a second segment. The first segment is configured to buckle upon application of a first critical force. The second segment includes an outer surface and an inner surface and is configured to buckle upon application of a second critical force. The second critical force is lower than the first critical force. The medical device further comprises a coil disposed radially inwardly of the inner surface of the second segment.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: May 16, 2017
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Eric S. Olson, James V. Kauphusman, Linda K. Nemec, Troy T. Tegg
  • Patent number: 9629568
    Abstract: A method and system provides for electrophysiological data analysis in a networked processing environment. The method and system includes receiving, via a networked connection, electrophysiological data of a patient and electronically performing, via at least one network processing device, a data analysis on the electrophysiological data. The method and system includes generating at least one report based on the data analysis, wherein the at least one report includes determination of one or more intervention options for the patient and therein transmitting the report to a recipient device across the network connection for utilization with the patient. The results of the report direct the user to apply from within the same system non-invasive brain stimulation, neurofeedback, and biofeedback modalities.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: April 25, 2017
    Assignee: EVOKE NEUROSCIENCE, INC.
    Inventors: David W Hagedorn, James W. G. Thompson
  • Patent number: 9601031
    Abstract: A medical attachment device position detection system for use during medical training including a processor and a medical attachment device communicatively coupled to the processor, a first magnetometer coupled to the medical attachment device and configured to detect a first angle, and a second magnetometer configured to detect a second angle. The second magnetometer is communicatively coupled to the processor. The processor is operably configured to compare a relationship of the first angle relative to the second angle to determine a position of the medical attachment device relative to a subject.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: March 21, 2017
    Inventor: Christian Raul Gutierrez Morales
  • Patent number: 9576107
    Abstract: A parametric model representing a portion of a heart is constructed using a statistical prior of the shape from a dataset of other instances of the portion. Using a mapping electrode, electrical data is acquired in a plurality of locations in the portion of the heart of a subject. The parametric model is fitted to the electrical data and the statistical prior to produce an isosurface of the portion of the heart and a reconstruction of its shape.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: February 21, 2017
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Moshe Safran, Meir Bar-Tal
  • Patent number: 9551688
    Abstract: [Problem to be Solved] To provide a property measuring device for measuring a measurement object, which can highly reliably extract an electric signal serving as the measurement object from an electromagnetic field noise or the like generated by an acoustic wave generating source even if the acoustic wave is a continuous wave, while a high spatial resolution is maintained, by using an acoustic wave as a properly measuring means for measuring an object and method thereof.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: January 24, 2017
    Assignee: TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY
    Inventor: Kenji Ikushima
  • Patent number: 9504395
    Abstract: Disclosed are devices, a systems, and methods for determining the dipole densities on heart walls. In particular, a triangularization of the heart wall is performed in which the dipole density of each of multiple regions correlate to the potential measured at various locations within the associated chamber of the heart.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: November 29, 2016
    Inventor: Christoph Scharf
  • Patent number: 9451883
    Abstract: Decoding and reconstructing a subjective perceptual or cognitive experience is described. A first set of brain activity data produced in response to a first brain activity stimulus is acquired from a subject using a brain imaging device. An encoding model is used to convert the brain activity data into a corresponding set of predicted response values. A second set of brain activity data produced in response to a second brain activity stimulus is acquired from a subject and decoded using a decoding distribution derived from the encoding model, and the probability the second set of brain activity data corresponds to said predicted response values is determined. The second set of brain activity stimuli is then reconstructed based on the probability of correspondence between the second set of brain activity data and the predicted response values.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: September 27, 2016
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jack L. Gallant, Thomas Naselaris, Kendrick Kay, Ryan Prenger
  • Patent number: 9427559
    Abstract: A centering tool and a combined centering-indicator tool for finding the magnetic center and indicating the setting of an implantable adjustable valve. The centering and combined centering-indicator tools include a magnetic capsule movable within a cavity to a target located on the tool when the magnetic capsule is centered over magnet of an adjustable valve.
    Type: Grant
    Filed: September 8, 2015
    Date of Patent: August 30, 2016
    Assignee: Medtronic Xomed, Inc.
    Inventors: Deep Shah, Tony Daniel Cepeda, Lori Speckman, W. Jeff Bertrand, Lawrence Hampton
  • Patent number: 9317920
    Abstract: A computer-based system and method(s) are described which detects and identifies implanted medical devices (“IMDs”) and/or retained surgical foreign objects (“RSFOs”) from diagnostic medical images. In some embodiments, the system provides further identification—information on the particular IMD and/or RSFO that has been recognized. For example, the system could be configured to provide information feedback regarding the IMD, such as detailed manual information, safety alerts, recalls, assess its' structural integrity, and/or suggested courses of action in a specific clinical setting/troubleshooting. Embodiments are contemplated in which the system is configured to report possible 3D locations of RSFOs in the surgical field/images.
    Type: Grant
    Filed: November 29, 2012
    Date of Patent: April 19, 2016
    Assignee: Rush University Medical Center
    Inventor: Vicko Gluncic
  • Patent number: 9255818
    Abstract: An electronic circuit detecting proximity includes an excitation coil emitting an inductive excitation field toward a target. A first pair of detection coils obtains a first differential inductive signal that is modified by a transition of the target within the inductive field. An out-of phase second pair of detection coils obtains a second differential inductive signal that is modified by a transition of the target within the inductive field. A comparator generates a transition signal when the difference between the first and second differential signals reaches a threshold value. A stationary target, in a ferromagnetic or conductive material, creates an offset to the signals at the outlet of the coil pairs. The offset is decreased during the presence of a movable target within the same type of material or increased during the presence of a movable target within another type of material. A comparator detects the offset level.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: February 9, 2016
    Assignee: Posic SA
    Inventors: Johan Bergqvist, Sietse Wouters
  • Patent number: 9179865
    Abstract: Strain gauges that can provide information with regard to the state of implantable devices are described. The strain gauges can exhibit luminescence that is detectable through living tissue, and the detectable luminescent emission can vary according to the strain applied to the gauge. A change in residual strain of the device can signify a loss of mechanical integrity and/or loosening of the implant, and this can be non-invasively detected either by simple visual detection of the luminescent emission or through examination of the emission with a detector such as a spectrometer or a camera.
    Type: Grant
    Filed: August 7, 2013
    Date of Patent: November 10, 2015
    Assignee: Clemson University
    Inventors: Jeffrey Anker, Melissa Rogalski, Dakota Anderson, Jonathon Heath
  • Patent number: 9173614
    Abstract: The use of machine learning for pattern recognition in magnetocardiography (MCG) that measures magnetic fields emitted by the electrophysiological activity of the heart is disclosed herein. Direct kernel methods are used to separate abnormal MCG heart patterns from normal ones. For unsupervised learning, Direct Kernel based Self-Organizing Maps are introduced. For supervised learning Direct Kernel Partial Least Squares and (Direct) Kernel Ridge Regression are used. These results are then compared with classical Support Vector Machines and Kernel Partial Least Squares. The hyper-parameters for these methods are tuned on a validation subset of the training data before testing. Also investigated is the most effective pre-processing, using local, vertical, horizontal and two-dimensional (global) Mahanalobis scaling, wavelet transforms, and variable selection by filtering.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: November 3, 2015
    Assignee: CardioMag Imaging, Inc.
    Inventors: Karsten Sternickel, Boleslaw Szymanski, Mark Embrechts
  • Patent number: 9125581
    Abstract: A system identifies double-layer dipoles in a magnetic image by defining two-dimensional patches of distributed point charges that simulate the double-layer dipoles. The geometric center of a two-dimensional patch is used as the location of an equivalent dipole moment of the double-layer dipole. The momentum of the equivalent dipole moment is determined by submitting the magnetic image to a dipole construction system that identifies the location and momentum based on the submitted magnetic image.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: September 8, 2015
    Assignee: Seiko Epson Corporation
    Inventors: Chenyu Wu, Jing Xiao
  • Patent number: 9113803
    Abstract: Disclosed is a magnetoencephalography meter which includes a plurality of optical pumping magnetometers which are arranged in a helmet shape to cover the head of the subject. Each optical pumping magnetometer has a vapor cell which is filled with alkali metal atoms and is arranged substantially in parallel to the surface of the head of the subject, a laser light emission unit that emits laser light in a direction toward the head of the subject and causes laser light to enter the vapor cell, a reflection unit that reflects laser light passed through the vapor cell in a direction away from the head of the subject which is a direction substantially perpendicular to the surface of the head of the subject, and a polarization change detection unit that receives laser light reflected by the reflection unit and detects change in polarization of laser light.
    Type: Grant
    Filed: November 20, 2013
    Date of Patent: August 25, 2015
    Assignee: Sumitomo Heavy Industries, Ltd.
    Inventor: Yanping Zhang
  • Patent number: 9042962
    Abstract: The present invention relates to a model based positioning system that includes a positioning device having at least one transmitter configured to be in a tracking environment, e.g. inserted into a body, a receiver having a plurality of receiver elements arranged outside the tracking environment, a control unit configured to measure amplitude and/or phase information of a signal transmitted from the at least one transmitter and received at each receiving element, and a memory unit M for storing a model for each receiving element. The control unit is also configured to estimate the position P of the positioning device by comparing the model for each receiving element with the measured received signal for each receiving element.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: May 26, 2015
    Assignee: MICROPOS MEDICAL AB
    Inventors: Roman Iustin, Johan Linder, Erik Isberg, Tomas Gustafsson, Bo Lennernäs
  • Publication number: 20150141798
    Abstract: A subject-specific skeletal model of a body is created, and an intended path of a catheter within the body is defined in the model. While the probe is inserted into the body electrical currents are passed through the body between at least one electrode in the probe and through respective electroconductive location pads that are disposed at a plurality of locations on the body surface along the intended path. Based on respective characteristics of the currents passing through the plurality of locations, position coordinates of the probe are iteratively determined. The actual path of the probe is tracked with reference to in the model using the iteratively determined position coordinates to determine whether the actual path corresponds to the intended path.
    Type: Application
    Filed: November 21, 2013
    Publication date: May 21, 2015
    Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventor: Meir Bar-Tal
  • Patent number: 9031633
    Abstract: In Magnetic Particle Imaging (MPI) the reconstruction requires the knowledge of a so called system function. This function describes the relation between spatial position and frequency response and is currently measured once for a scanner set-up and a tracer material. For reasonable resolutions and fields of view the system function becomes quite large, resulting in large acquisition times to obtain reasonable signal-to-noise. However, the system function has a number of properties which can be used to improve signal-to-noise. According to the present invention use is made of the spatial symmetry and/or identical responses at different frequencies for this purpose.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: May 12, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Juergen Erwin Rahmer, Jeurgen Weizenecker, Bernhard Gleich
  • Patent number: 9031634
    Abstract: A new and improved method for tracking and/or spatial localization of an invasive device in Magnetic Resonance Imaging (MRI) is provided. The invention includes providing an invasive device including a marker having a chemically shifted signal source with a resonant frequency different from the chemical species of the subject to be imaged, applying a pulse sequence, detecting the resulting RF magnetic resonance signals, and determining the 3D coordinates of the marker. The invention also includes generating scan planes and reconstructing an image from the detected signals to generate an image having the marker contrasted from the subject. The invasive device includes a marker having a chemically shifted signal source which has a resonant frequency different from the chemical species of the subject to be imaged for use in tracking the device during imaging.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: May 12, 2015
    Inventors: Christopher Flask, Jonathan Lewin, Daniel Elgort, Ken Pin Wang, Eddy Wong, Jeffrey Duerk
  • Publication number: 20150126829
    Abstract: The present disclosure describes system and methods for detecting and amplifying weak magnetic fields generated by anatomical structures. The disclosure describes an implantable magnetic reporter system. The magnetic reporter system includes a magnetic reporter. The magnetic reporter includes a platform coupled to a support structure by a plurality of torsional flexures. A magnet is disposed on the platform, and the magnet and platform rotate when exposed to a magnetic field. The rotation of the magnet generates a stronger magnet field that is detectable external to the patient.
    Type: Application
    Filed: November 5, 2014
    Publication date: May 7, 2015
    Inventor: Jonathan J. Bernstein
  • Patent number: 9026194
    Abstract: Apparatus and methods which enable the stimulation of neurons oriented in all directions within a biological structure using applied magnetic fields.
    Type: Grant
    Filed: July 8, 2013
    Date of Patent: May 5, 2015
    Assignee: Moment Technologies, LLC
    Inventor: Yoshio Okada
  • Publication number: 20150119686
    Abstract: An apparatus, including a bus having electrical power and data lines, and a plurality of location pads, which are positionable at different, respective locations with respect to a body cavity in which the object is located, and which are connected to the bus in series so as to receive electrical power and exchange data signals over the bus. Each location pad includes multiple radiator coils and driving circuitry configured to select, responsively to the data signals, different respective driving frequencies for the coils and to generate, using the electrical power from the bus, driving signals to drive the coils to produce magnetic fields at the respective driving frequencies. The apparatus also includes a console, which is configured to receive and process sensor signals from a magnetic sensor fixed to the object, in response to the magnetic fields in the body cavity, in order to compute position coordinates of the object.
    Type: Application
    Filed: October 25, 2013
    Publication date: April 30, 2015
    Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Assaf Govari, Yaron Ephrath, Andres Claudio Altmann
  • Publication number: 20150119687
    Abstract: A method is described for estimating skin thickness over an implanted magnet. A plane is defined that is perpendicular to the skin of a patient over an implanted magnet and characterized by x- and y-axis coordinates. The magnetic field strength of the implanted magnet is measured using an array of magnetic sensors on the skin of the patient. From the measured magnetic field strength, at least one x-axis coordinate in the plane is determined for at least one y-axis zero position on the array where a y-axis component of the measured magnetic field strength is zero. From that, a y-axis coordinate of the at least one y-axis zero is calculated as a function of the at least one x-axis coordinate, such that the y-axis coordinate represents thickness of the skin over the implanted magnet.
    Type: Application
    Filed: October 24, 2014
    Publication date: April 30, 2015
    Inventor: Christoph Hornsteiner
  • Patent number: 9020575
    Abstract: A apparatus includes an acquisition unit to acquire magnetic resonance data in every data group, a unit to control the acquisition unit to collect the data for one or a plurality of data groups during a collection period which is set based on a starting time phase of a cardiac cycle of the subject, a unit to determine the data among the data acquired by the acquisition unit as ineffective data if at least a part of it is related to a data group acquired during an ineffective period, and as effective data if all of it is related to a data group acquired during a period other than the ineffective period, the ineffective period being set based on an ending time point of the cardiac cycle in which the data is acquired, and a unit to reconstruct an image regarding the subject by using the effective data.
    Type: Grant
    Filed: November 7, 2007
    Date of Patent: April 28, 2015
    Assignees: Kabushiki Kaisha Toshiba, Toshiba Medical Systems Corporation
    Inventor: Satoshi Sugiura
  • Patent number: 9008749
    Abstract: The present invention relates to an apparatus and a method for influencing and/or detecting magnetic particles in a field of view.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: April 14, 2015
    Assignee: Koninklijke Philips N.V.
    Inventors: Thorsten Manuel Buzug, Timo Frederik Sattel, Tobias Knopp, Sven Biederer
  • Publication number: 20150099962
    Abstract: Method and device for the automatic identification of phase-locked high-frequency oscillations (PLHFO) to localize epileptogenic brain for neurosurgical intervention, including filtering brain signals into low frequency and high frequency oscillation (HFO) data streams. Applying ICA to the HFO data stream, transforming the data streams to produce an HFO instantaneous amplitude (HFOIA) and a low-frequency instantaneous phase (LFIP) data stream. Transforming the normalized HFOIA to produce an instantaneous phase of the normalized HFOIA. Determining a continuous or discrete PLHFO calculation that measures cross frequency coupling between the instantaneous phase of the low frequency data stream, and the instantaneous amplitude of the HFO data stream based at least in part on LFIP, raw or normalized HFOIA, and may include the instantaneous phase of normalized or raw HFOIA.
    Type: Application
    Filed: October 6, 2014
    Publication date: April 9, 2015
    Inventors: Shennan Aibel Weiss, Catherine A. Schevon
  • Publication number: 20150087945
    Abstract: A method of making a sensor includes depositing a layer of hydrogel over a substrate, the hydrogel configured to change thickness or volume in response to a selected condition and including a plurality of magnetic particles disposed in the hydrogel so that a magnetic property of the hydrogel changes with changes of thickness or volume of the hydrogel. The hydrogel is sacrificed in selected region(s) of the layer so that the hydrogel outside the selected region(s) forms a plurality of spaced-apart islands of the hydrogel. The islands of the hydrogel are enclosed in an enclosure at least partly permeable to a selected fluid. A sensor for detecting a condition includes the substrate, islands, and a device coil arranged with respect to the hydrogel so that changes in the magnetic property modulate an electrical property of the sensor. A system includes the substrate, islands, and a magnetic-field detector.
    Type: Application
    Filed: December 1, 2014
    Publication date: March 26, 2015
    Inventors: Babak Ziaie, Ronald A. Siegel
  • Publication number: 20150080703
    Abstract: Systems and methods for evaluating prospective treatments for progressive brain disorders like Alzheimer's disease and the progressive effects of aging involve the use of an imaging device communicatively coupled to a computing device. The imaging device may takes a plurality of brain imaging measurements from each of a plurality of human subjects who are divided into a treated group and an untreated group based on various subject data including whether the subjects carry certain alleles of genes known to increase the risk of developing the brain disorder at issue. The computing device receives the brain imaging measurements from the imaging device and applies an advanced processing method that permits enhanced computational efficiency when calculating rates of change for the two groups and determining whether any calculated difference between the rates is statistically significant.
    Type: Application
    Filed: October 8, 2014
    Publication date: March 19, 2015
    Inventor: Eric M. Reiman
  • Patent number: 8981765
    Abstract: It is an object of the present invention to provide a motor function analyzing apparatus which simplifies a calibration measurement necessary before measuring a finger tapping motion, and which is capable of evaluating a motor function highly precisely. The present invention provides a motor function analyzing apparatus which simplifies a calibration measurement necessary before measuring a finger tapping motion, and which is capable of evaluating a motor function highly precisely by using a calibration point unique to each apparatus and a calibration point unique to each subject.
    Type: Grant
    Filed: April 27, 2011
    Date of Patent: March 17, 2015
    Assignee: Hitachi Maxell, Ltd.
    Inventors: Yuko Sano, Akihiko Kandori, Tsuyoshi Miyashita, Katsuya Morohoshi, Kouichi Ishizuka
  • Publication number: 20150065851
    Abstract: A method, including inserting a probe into a cavity in a subject's body and receiving, from a force sensor in the probe, first readings indicative of a first change in measured contact forces between the probe and the cavity by less than a predetermined limit over at least a predetermined interval of time. The method continues by receiving second readings from the force sensor when the second readings have changed by more than a predetermined force threshold or location coordinates of the probe have changed by at least a predetermined location change threshold. The method continues by receiving third readings indicative of a second change in the measured contact forces between the probe and the cavity by less than the predetermined limit over at least the predetermined interval of time. The method concludes by calibrating a zero-force point for the force sensor according to the third readings.
    Type: Application
    Filed: August 27, 2013
    Publication date: March 5, 2015
    Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Doron Moshe Ludwin, Aharon Turgeman, Natan Sharon Katz, Erez Silberschein