Visible Light Radiation Patents (Class 600/476)
  • Patent number: 11348227
    Abstract: Methods and systems for analyzing images are disclosed. An example method may comprise inputting one or more of a first image or a second image into a fully convolutional network, and determining an updated fully convolutional network by optimizing a similarity metric associated with spatially transforming the first image to match the second image. The one or more values of the fully convolutional network may be adjusted to optimize the similarity metric. The method may comprise registering one or more of the first image or the second image based on the updated fully convolutional network.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: May 31, 2022
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Yong Fan, Hongming Li
  • Patent number: 11338101
    Abstract: An oxygen supply device supplying a user with an oxygen gas for inhalation acquires information of the user on percutaneous arterial oxygen saturation (SpO2) using a sensor unit, and calculates, from SpO2, the first moving average value and the second moving average value calculated over a time span longer than the first moving average in a control unit. The control unit calculates a Dip frequency during predetermined time from the SpO2 information, and when the calculated frequency is equal to or larger than the first threshold, the control unit switches the control from the control based on the first moving average value of SpO2 to the control based on the second moving average value.
    Type: Grant
    Filed: March 19, 2018
    Date of Patent: May 24, 2022
    Assignee: Teijin Pharma Limited
    Inventors: Ryo Koizumi, Sadayoshi Matsumoto
  • Patent number: 11330973
    Abstract: An endoscopic system includes a single-use portion and a multiple-use portion. The two portions can be mated and un-mated. The single-use portion includes an elongated cannula that has a bendable section near its distal end providing a “steerable” distal tip. The imaging system includes at least two separate cameras and two separate light sources. The camera and light sources are configured to simultaneously image a target object. By employing different illuminations, different filters and manipulating the spectral responses, different characteristics of the target object can be captured. According to some embodiments, a system processor can coordinate the cameras, the light sources and combine the resulting images to display to an operator an enhanced combined image the object.
    Type: Grant
    Filed: September 13, 2021
    Date of Patent: May 17, 2022
    Assignee: MicronVision Corp
    Inventors: Xiaolong Ouyang, Shih-Ping Wang
  • Patent number: 11317787
    Abstract: The disclosed subject matter includes devices and systems for extending the imaging capability of swept, confocally aligned planar excitation (SCAPE) microscopes to in vivo applications. In embodiments, the SCAPE microscope can be implemented as an endoscopic or laparoscopic inspection instrument.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: May 3, 2022
    Assignee: The Trustees of Columbia University in the City of New York
    Inventor: Elizabeth Marjorie Clare Hillman
  • Patent number: 11316318
    Abstract: A surgical laser system includes a pump module configured to produce pump energy within an operating wavelength, a gain medium configured to convert the pump energy into first laser energy, a non-linear crystal (NLC) configured to convert a portion of the first laser energy into second laser energy, which is a harmonic of the first laser energy, an output, and a first path diversion assembly having first and second operating modes. When the first path diversion assembly is in the first operating mode, the first laser energy is directed along the output path to the output, and the second laser energy is diverted from the output path and the output. When the first path diversion assembly is in the second operating mode, the second laser energy is directed along the output path to the output, and the first laser energy is diverted from the output path and the output.
    Type: Grant
    Filed: September 9, 2019
    Date of Patent: April 26, 2022
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Honggang Yu, Rongwei Jason Xuan, Jian James Zhang
  • Patent number: 11294062
    Abstract: Systems, methods, and devices for laser mapping and color imaging with increased dynamic range are disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation, wherein the pixel array comprises a plurality of pixels each configurable as a short exposure pixel or a long exposure pixel. The system includes a controller comprising a processor in electrical communication with the image sensor and the emitter.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: April 5, 2022
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 11284801
    Abstract: A method to visualize, display, analyze and quantify angiography, perfusion, and the change in angiography and perfusion in real time, is provided. This method captures image data sequences from indocyanine green near infra-red fluorescence imaging used in a variety of surgical procedure applications, where angiography and perfusion are critical for intraoperative decisions.
    Type: Grant
    Filed: March 18, 2019
    Date of Patent: March 29, 2022
    Assignee: Stryker European Operations Limited
    Inventors: T. Bruce Ferguson, Jr., Cheng Chen
  • Patent number: 11284785
    Abstract: Controlling integral energy of a light pulse in a hyperspectral, fluorescence, and laser mapping imaging system is disclosed. A system includes an emitter for emitting pulses of electromagnetic radiation and an image sensor comprising a pixel array for sensing reflected electromagnetic radiation. The system includes an electromagnetic sensor for sensing energy emitted by the emitter. The system includes a controller configured to synchronize timing of the emitter and the image sensor. The system is such that at least a portion of the pulses of electromagnetic radiation emitted by the emitter comprises one or more of a hyperspectral emission, a fluorescence emission, or a laser mapping pattern.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: March 29, 2022
    Inventors: Joshua D. Talbert, Donald M. Wichern
  • Patent number: 11282132
    Abstract: The present invention relates to frameworks and methodologies configured to enable generation and utilisation of three-dimensional body scan data. Various embodiments are described by reference to applications by which body scan data is collected, and/or subsequently utilised in the context of providing downstream functionalities, for example in the context of enabling users and/or business derive benefit from three-dimensional body scan data.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: March 22, 2022
    Assignee: mPort Ltd
    Inventors: Tsung-Yuan Wu, Dipra Ray
  • Patent number: 11278248
    Abstract: A catheter system includes a catheter body, an imaging sensor, a drive motor, a current sensor, a display, and a controller. The catheter body includes a drive shaft. The imaging sensor is fixed relative to the distal end of the driveshaft and is configured to rotate therewith. The drive motor is configured to rotate the drive shaft. The current sensor is configured to measure an amount of current drawn by the drive motor as the drive shaft is rotated. The display is configured to display one or more images obtained by the imaging sensor as the imaging sensor is rotated. The controller is configured to adjust a rotational orientation of the one or more images displayed by the display based upon the measured current.
    Type: Grant
    Filed: January 25, 2017
    Date of Patent: March 22, 2022
    Assignee: Avinger, Inc.
    Inventor: Bjarne B. Christensen
  • Patent number: 11278210
    Abstract: The pulse wave detecting device includes a sensor section in which two element rows consisting of a plurality of pressure detecting elements arranged in a direction B are arranged in a direction A perpendicular to the direction B, and an air bag pressing the sensor section to a body surface in a state that the direction B intersects a direction in which an artery below the body surface of a living body. An arrangement interval between the two element rows in the direction A is 5 mm or more and 15 mm or less.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: March 22, 2022
    Assignee: OMRON HEALTHCARE CO., LTD.
    Inventors: Tsuyoshi Kitagawa, Shingo Yamashita, Toshihiko Ogura, Masayuki Fukutsuka, Daizo Oka, Naomi Matsumura, Kentaro Mori, Hiroyuki Kinoshita, Masayuki Wakamiya
  • Patent number: 11272984
    Abstract: Systems and methods are provided in which devices that are employed during a medical procedure are adaptively configured during the medical procedure, based on input or feedback that is associated with the current state, phase or context of the medical procedure. In some example embodiments, the input is obtained via the identification of one or more medical instruments present within a region of interest, and this input may be employed to determine configuration parameters for configuring the device. In other example embodiments, the input may be based on the image-based detection of a measure associated with the phase or context of the medical procedure, and this input may be employed to adaptively control the device based on the inferred context or phase of the medical procedure. In other embodiments, images from one imaging modality may be employed to adaptively switch to another imaging modality.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: March 15, 2022
    Assignee: SYNAPTIVE MEDICAL INC.
    Inventors: Cameron Piron, Michael Wood, Gal Sela, Joshua Richmond, Murugathas Yuwaraj, Stephen McFadyen, Alex Panther, Nishanthan Shanmugaratnam, William Lau, Monroe M. Thomas, Wes Hodges, Simon Alexander, David Gallop
  • Patent number: 11273002
    Abstract: A display system includes an irradiator, an imager, an image generator, a projector, a display, and an adjuster. The irradiator irradiates an object with light having a wavelength in an invisible light region. The imager captures an invisible light image based on light excited by the light having the wavelength in the invisible light region, and a visible light image based on light in a visible light region, in the object. The image generator generates a projection image based on the invisible light. The projector projects the projection image onto the object with visible light. The display displays the invisible light image, the visible light image and the projection image in a superimposed manner with each other. The adjuster adjusts the projection image on the display, based on a user operation. The projector projects the projection image adjusted by the adjuster.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: March 15, 2022
    Assignee: PANASONIC CORPORATION
    Inventor: Masaaki Nakamura
  • Patent number: 11266308
    Abstract: Provided are a method and a device for evaluating a tear fluid to objectively evaluate and determine the severity of dry eye or the like. Color information is acquired in a predetermined region of a tear fluid interference fringe image, a numerical value representing a color diversity is calculated from the color information acquired, and the numerical value representing the color diversity thus calculated is used as an index for evaluating a tear fluid state.
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: March 8, 2022
    Assignee: Kowa Company, Ltd.
    Inventor: Katsumi Yabusaki
  • Patent number: 11244452
    Abstract: A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.
    Type: Grant
    Filed: October 16, 2018
    Date of Patent: February 8, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Carlos Castro-Gonzalez, Ian Butterworth, Aurelien Bourquard, Alvaro Sanchez-Ferro, Jason Tucker-Schwartz, Alberto Pablo-Trinidad, Maria J. Ledesma-Carbayo, Tom Vettenburg
  • Patent number: 11234751
    Abstract: Systems, methods, and other embodiments associated with characterizing Radio Frequency Ablation (RFA) lesions using Optical Coherence Tomography (OCT) are described. One example method includes acquiring an OCT signal from a Region Of Interest (ROI) in an ablated material. The example method may also include determining whether a lesion was formed by the ablation by analyzing optical properties of the ROI as recorded in the OCT signal.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: February 1, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Andrew M. Rollins, Christine P. Fleming
  • Patent number: 11235169
    Abstract: An Illumination device (100) for photodynamic therapy is provided, the illumination device comprising at least one electromagnetic radiation emitting unit (10), the at least one electromagnetic radiation emitting unit comprising at least one electromagnetic radiation source (1), the electromagnetic radiation source being configured to generate radiation for the irradiation of a region of an irradiation object in an illumination session, wherein the irradiation object is to be arranged at a predetermined object location (300), wherein the predetermined object location is arranged at a distance relative to a radiation output area (11) of the radiation emitting unit through which the radiation generated by the at least one electromagnetic radiation source exits the radiation emitting unit during operation of the illumination device (100).
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: February 1, 2022
    Assignee: BIOFRONTERA PHARMA GMBH
    Inventors: Markus Osterloh, Ben Novak, Hermann Lübbert
  • Patent number: 11231779
    Abstract: A brain computer interface (BCI) module includes a flexible printed circuit assembly (FPCA) configured to conform to the head of a user. A plurality of emitters and a plurality of detectors are mounted on the FPCA. Each emitter of the plurality is configured to emit light towards the head of the user and each detector is configured to detect the emitted light. An array of ferrules is additionally mounted to the FPCA such that each ferrule of the array encases an emitter or a detector. The BCI module additionally includes a controller that is configured to receive an optical signal detected by a detector of the plurality and to encode the detected signal into a biological signal.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: January 25, 2022
    Assignee: Meta Platforms, Inc.
    Inventors: John Michael Sundberg, Frances Wing Yee Lau, E-Fann Saung, Ealgoo Kim
  • Patent number: 11224393
    Abstract: A fluoroscopy system includes a fluoroscopy device, an indicating assembly and a center control device. The fluoroscopy device includes a contoured support arm, an X-ray emitting unit, an X-ray sensor and a display unit. The contoured support arm has a first end part and a second end part opposite to the first end part. The X-ray emitting unit is located on the first end part and is configured to emit an X-ray. The X-ray sensor is located on the second end part to sense the X-ray. The display unit is electrically connected to the X-ray sensor. The indicating assembly is located near the contoured support arm and includes a plurality of light emitting units. Each of the plurality of light emitting units is rotatable and configured to emit a light plane. The center control device is electrically connected to the fluoroscopy device and the indicating assembly.
    Type: Grant
    Filed: August 24, 2020
    Date of Patent: January 18, 2022
    Inventors: Chen-Kun Liaw, Tai-Yin Wu
  • Patent number: 11215902
    Abstract: Example implementations relate to ferromagnetic covers. For instance, in an example housing can include a bezel including first opening extending through a recess included in the bezel, a first magnet and a second magnet in an internal volume of the housing, and a ferromagnetic cover disposed in the recess and magnetically coupled to the first magnet and the second magnet, where the ferromagnetic cover includes a second opening to obscure a viewing portion of the first opening with the continuous portion when the ferromagnetic cover is positioned adjacent to a first side surface of the recess.
    Type: Grant
    Filed: April 10, 2017
    Date of Patent: January 4, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Derek Kanas, Tony Moon, Chan-Woo Park
  • Patent number: 11207040
    Abstract: The invention concerns a dental imaging apparatus comprising: —a support frame, —a movable gantry that comprises two opposite arms respectively supporting an x-ray source and an x-ray sensor facing the x-ray source, —a movable patient positioning arm connected to the support frame, —two cameras positioned on the gantry arm supporting the x-ray source and on the positioning arm so as to respectively acquire side and front images of a patient's head, —a display assembly configured to simultaneously display in real time a side image and a front image of the patient's head taken by the two cameras.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: December 28, 2021
    Inventors: Stephane Varlet, Olivier Nesme, Laurent Boutte, Aude Lagardere, Stephane Alric
  • Patent number: 11202675
    Abstract: The present invention relates to a computer-implemented medical data processing method, a corresponding computer program and a corresponding system for planning an implant placement into an anatomical structure of a patient, which allows a user to modify the implant placement within a frame defined by predefined requirements that have to be fulfilled for achieving a desired medical outcome.
    Type: Grant
    Filed: June 14, 2017
    Date of Patent: December 21, 2021
    Assignee: BRAINLAB AG
    Inventors: Joerg Uhde, Thomas Drexl, Martin Koestler
  • Patent number: 11200665
    Abstract: A fundus image processing method comprising: receiving a collected fundus image; identifying the fundus image via a first neural network to generate a first feature set of the fundus image; identifying the fundus image via a second neural network to generate a second feature set of the fundus image, wherein the first feature set and the second feature set indicate different lesion attributes of the fundus image; combining the first feature set and the second feature set to obtain a combined feature set of the fundus image; and inputting the combined feature set into a classifier to obtain a classification result.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 14, 2021
    Assignees: SHANGHAI SIXTH PEOPLE'S HOSPITAL, SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Weiping Jia, Bin Sheng, Huating Li, Ling Dai
  • Patent number: 11185225
    Abstract: An ophthalmic surgical microscope includes a beam coupler positioned along an optical path of the surgical microscope between a first eyepiece and magnifying/focusing optics, the beam coupler operable to direct the OCT imaging beam along a first portion of the optical path of the surgical microscope between the beam coupler and a patient's eye (an OCT image being generated based on a reflected portion of the OCT imaging beam). The surgical microscope additionally includes a real-time data projection unit operable to project the OCT image generated by the OCT system and a beam splitter positioned along the optical path of the surgical microscope between a second eyepiece and the magnifying/focusing optics. The beam splitter is operable to direct the projected OCT image along a second portion of the optical path of the surgical microscope between the beam splitter and the second eyepiece such that the projected OCT image is viewable through the second eyepiece.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: November 30, 2021
    Assignee: Alcon Inc.
    Inventors: Tammo Heeren, Hugang Ren, Vadim Shofman, Lingfeng Yu
  • Patent number: 11187581
    Abstract: Disclosed is an optical micro-spectrometry system including an optical microscope, a spectrometry system and an optical system adapted to direct an excitation light beam on the sample through the at least one microscope objective and to collect a Raman or PL light beam from a sample. The optical micro-spectrometry system includes an imaging system configured for acquiring a first image and a second image of the sample, by reflection or transmission of an illumination beam from a sample surface, the first image having a large field of view and the second image having a small field of view, a processing system configured for determining an area in the first image corresponding to the second image, a display system configured for displaying the first image, the second image, and a third image representing the area in overlay on the first image.
    Type: Grant
    Filed: January 23, 2018
    Date of Patent: November 30, 2021
    Assignee: HORIBA FRANCE SAS
    Inventors: Alexandre Kokota, Vasyl Shynkar, Cédric Marchessoux
  • Patent number: 11179080
    Abstract: Embodiments herein relate to systems and methods for rapidly calibrating optical medical sensors. In an embodiment, a method can include placing a reflective optical medical sensor device on or in a patient. The reflective optical medical sensor device can include one or more optical emitters; one or more optical detectors; and a measurement circuit having one or more transimpedance amplifiers (TIA). The method can include setting the TIA to a fixed gain value and then turning on the optical emitter associated with each spatially unique measurement vector and receiving reflected light with the associated optical detector for each spatially unique measurement vector at the same fixed gain value. The method can include assessing the signal-to-noise (SNR) for each spatially unique measurement vector and selecting the spatially unique measurement vector having the highest SNR. Other embodiments are also included herein.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: November 23, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: George Wilfred Duval, Gang Hu
  • Patent number: 11179574
    Abstract: A method of administering 5-aminolevulinic acid (ALA) to a patient uses an adjustable illuminator for photodynamically diagnosing or treating a surface and which includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of first panels or the at least one second panel and configured to irradiate the surface with substantially uniform intensity visible light. The plurality of first panels and the at least one second panel are rotatably connected. The at least one second panel is connected on each side to one of the plurality of first panels. The second panel acts as a “lighted hinge” to reduce or eliminate optical dead spaces between adjacent panels when the illuminator is bent into a certain configuration.
    Type: Grant
    Filed: September 2, 2020
    Date of Patent: November 23, 2021
    Assignee: DUSA PHARMACEUTICALS, INC.
    Inventors: Thomas Boyajian, Mark Carota, Brian Mazejka
  • Patent number: 11172817
    Abstract: A fundus image capture system operates to determine if the system has captured an image that identifies the fundus, a region of interest in the image, or the current field of view. According to the determination, the system can guide the user to operate the system to capture a desired fundus image.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: November 16, 2021
    Assignee: Welch Allyn, Inc.
    Inventors: Allen R. Hart, Ynjiun P. Wang
  • Patent number: 11172900
    Abstract: Methods, devices and systems are provided that utilize one or more processors in connection with, receiving OA/US feature scores in connection with OA/US images collected from a patient examination for a volume of interest. The methods, devices and systems apply the OA/US feature scores to a feature score to molecular subtype (FSMS) model. The methods, devices and systems determine, from the FSMS model, an indication of at least one of a molecular subtype or histologic grade of a pathology experienced by the patient.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: November 16, 2021
    Assignee: Seno Medical Instruments, Inc.
    Inventor: Anthony Thomas Stavros
  • Patent number: 11166640
    Abstract: This disclosure relates to methods for measuring one or more physiological signals while the user is engaged in a predetermined activity. Exemplary predetermined activities can include activities such as walking, climbing stairs, biking, and the like. The physiological measurements can include, but are not limited to, heart rate signals. The physiological measurements may be affected by the predetermined activity, so the system may be configured to employ one or more criteria prior to measuring physiological information to minimize the effects. The one or more criteria can include, but are not limited to, an inter-sampling waiting time, continuous motion criteria, predetermined activity criteria, a post-physiological measurement amount of time, and a confidence value. The continuous motion criteria can be based on the type of predetermined activity. For example, walking may have walking state criteria and a step count criteria.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: November 9, 2021
    Assignee: Apple Inc.
    Inventors: Siyi Deng, Stephen J. Waydo, Jay Blahnik, Lun Dong, Ian R. Shapiro
  • Patent number: 11162844
    Abstract: The present invention is a camera with video-rate acquisition and processing for medical imaging applications. In particular, the invention is used to determine the health of a body area by quantitatively measuring blood oxygen levels and melanin content from a real-time video image of a body segment. In certain embodiments, a camera comprises an objective lens; a filter tray located at an aperture stop of the objective lens, wherein the filter tray comprises a plurality of elements, each element passes a spectral band of light; a micro-lens array located at an exit pupil of the objective lens comprising a plurality of micro lenses to form an image plane, wherein the objective lens produces a focused image at the image plane; and a focal plane array comprising a plurality of sensors, wherein each sensor receives light from at least one micro-lens of the micro-lens array.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: November 2, 2021
    Assignee: Surface Optics Corp.
    Inventors: Kyle Ryan McCormick, Jaclyn Nascimento, Mark Dombrowski
  • Patent number: 11162900
    Abstract: A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: November 2, 2021
    Assignees: THE TRUSTEES OF DARTMOUTH COLLEGE, UNIVERSITY HEALTH NETWORK
    Inventors: Keith D. Paulsen, David W. Roberts, Dennis Wirth, Brian C. Wilson, Mira Sibai
  • Patent number: 11160470
    Abstract: In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data.
    Type: Grant
    Filed: May 31, 2016
    Date of Patent: November 2, 2021
    Assignee: The Regents of the University of California
    Inventors: Bruce J. Tromberg, Kyle Cutler, Chris Van Wagenen, Seung-ha Lee, Thomas O'Sullivan, Gopi Meenakshisundaram, Aditi Majumder, Albert Cerussi
  • Patent number: 11162895
    Abstract: The present disclosure provides systems and methods for characterizing and monitoring biological material. In one aspect, a method for characterizing biological material includes acquiring optical data associated with a biological material, and analyzing the optical data to determine optical properties of the biological tissue. The method also includes determining, using the optical properties, phase information corresponding to the biological material, and generating a report characterizing the biological tissue using at least the phase information.
    Type: Grant
    Filed: November 5, 2020
    Date of Patent: November 2, 2021
    Assignee: The General Hospital Corporation
    Inventors: Amir Y. Sajjadi, Stefan A. Carp, Dieter Manstein
  • Patent number: 11154194
    Abstract: Principles of the present disclosure are directed to novel methods and devices for focal or global optical stimulation of retina and detecting activity of the retina by collecting and processing the back-scattered optical signal from the retina (Optical RetinoGram). Specifically, the invention provides device and method for quantitatively determining the layer specific activity of retina from the acquired intrinsic back reflected signal by monitoring phase/intensity fluctuations and thereafter employing multifractality algorithm on optical signal for obtaining various multifractal parameters such as width of singularity spectrum, Hurst exponent, fractal dimension, locally connected fractal mapping as well as artificial intelligence based classification for the use of diagnosis of retinal degenerative/ocular disease(s) and asses the progression of diseases or recovery of function due to one or more treatment by therapeutic drugs, devices, protocols.
    Type: Grant
    Filed: November 4, 2018
    Date of Patent: October 26, 2021
    Inventors: Samarendra Kumar Mohanty, Subrata Batabyal
  • Patent number: 11150173
    Abstract: Laser speckle microrheology is used to determine a mechanical property of a biological tissue, namely, an elastic modulus. Speckle frames may be acquired by illuminating a coherent light and capturing back-scattered rays in parallel and cross-polarized states with respect to illumination. The speckle frames may be analyzed temporally to obtain diffuse reflectance profiles (DRPs) for the parallel-polarized and cross-polarized states. A scattering characteristic of particles in the biological tissue may be determined based on the DRPs, and a displacement characteristic may be determined based at least in part on a speckle intensity autocorrelation function and the scattering characteristic. A size characteristic of scattering particles may be determined based on the DRP for the parallel polarization state. The mechanical property may be calculated using the displacement and size characteristics.
    Type: Grant
    Filed: February 13, 2017
    Date of Patent: October 19, 2021
    Assignee: The General Hospital Corporation
    Inventors: Seemantini K. Nadkarni, Zeinab Hajjarian
  • Patent number: 11147440
    Abstract: An otoscope device is disclosed comprising a radiation sensing unit configured for detecting radiation reflected by the patient's outer ear, especially by the eardrum. The otoscope device further comprises electronic and/or optic means configured for determining spectral information of reflected radiation, especially with respect to wavelengths shorter than 500 nm to 480 nm, and configured for determining a ratio of radiation in the spectrum below 480 nm to 500 nm to radiation in the spectrum above 480 nm to 500 nm, especially based on a specific intensity of reflected radiation within the spectrum of blue light and/or UV radiation. Further, a method is disclosed for identifying and/or locating objects in a subject's ear or to a method of identifying or characterizing an eardrum. Still further, a method is disclosed for determining the risk of a pathologic state of the eardrum and its vicinity and to provide the user with a risk index for inflammation.
    Type: Grant
    Filed: May 5, 2015
    Date of Patent: October 19, 2021
    Assignee: Helen of Troy Limited
    Inventor: Albrecht Lepple-Wienhues
  • Patent number: 11140302
    Abstract: A wearable device, such as a ring, is used to be worn on at least one part of a human body. A wearable device includes a body having a bottom surface and a top surface, an opening defined between the top surface and the bottom surface. The opening is used to receive therethrough and hold the at least one part of the human body. A pocket is defined in the body between the opening and the top surface for holding the camera presenting an activation button to turn on and turn off the camera. The body includes a membrane defined in the top surface of the body.
    Type: Grant
    Filed: November 26, 2020
    Date of Patent: October 5, 2021
    Inventor: Charles Hudson
  • Patent number: 11134848
    Abstract: A mobile hyperspectral camera system is described. The mobile hyperspectral camera system comprises a mobile host device comprising a processor and a display: a plurality of cameras, coupled to the processor, configured to capture images in distinct spectral bands; and a hyperspectral flash array, coupled to the processor, configured to provide illumination to the distinct spectral bands. A method of implementing a mobile hyperspectral camera system is also described.
    Type: Grant
    Filed: January 4, 2017
    Date of Patent: October 5, 2021
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Raja Bala, Sourabh Ravindran, Hamid Rahim Sheikh, Youngjun Yoo, Michael Oliver Polley
  • Patent number: 11140305
    Abstract: An imaging device having an imaging field of view, the imaging device including at least one illumination port configured to output light for illuminating a target; an imaging sensor to detect light traveling along an optical path to the imaging sensor; and a first movable window positioned upstream of the sensor with respect to a direction of travel of light along the optical path, wherein the first movable window is configured to move into the optical path in a deployed position for modifying light received from the target.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: October 5, 2021
    Assignee: Stryker European Operations Limited
    Inventor: Paul Roald Westwick
  • Patent number: 11134851
    Abstract: A multi-sensor device may perform an optical measurement using an optical sensor of the multi-sensor device, where the optical measurement is performed when a surface of the multi-sensor device is in contact with a human body. The multi-sensor device may perform another measurement using at least one other sensor of the multi-sensor device, where the other measurement is performed when the surface of the multi-sensor device is in contact with the human body, where the other measurement is performed substantially contemporaneously with the optical measurement, and where the optical measurement and the other measurement relate to health parameters. The multi-sensor device may determine a combined measurement value based on the optical measurement and the other measurement.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: October 5, 2021
    Assignee: VIAVI Solutions Inc.
    Inventors: William D. Houck, Marc K. Von Gunten
  • Patent number: 11109806
    Abstract: A three dimensional imaging system includes a first laser emitting light at a first wavelength, and a scanner for scanning the laser light in a pattern on the target area. A photo detector receives light reflected from the target area as a contrasted vein image, resulting from differential absorption and reflection therein of the first wavelength of light. The intensity of the first laser is incrementally increased, and the photo detector thereby receives a plurality of contrasted vein images, each being at incrementally distinct depths beneath the target skin surface. Image processing is performed on the plurality of vein images to successively layer the veins in the images according to their depth, to create a single processed vein image. A second laser emitting a second wavelength of light is used in combination with the scanner to project the processed vein image onto the target area to overlay the veins therein.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: September 7, 2021
    Assignee: AccuVein, Inc.
    Inventors: Ron Goldman, Fred Wood, Stephen P. Conlon, Vincent Luciano
  • Patent number: 11105790
    Abstract: Provided herein are compositions and methods for diagnosing parasitic infections. In particular, provided herein are compositions and methods for preparing samples (e.g., canine fecal samples) and performing Raman spectroscopy detection of parasites infections in the samples.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: August 31, 2021
    Assignee: Zomedica Corp.
    Inventors: Stephanie Morley, Casey Wegner
  • Patent number: 11100654
    Abstract: Present embodiments pertain to systems, apparatuses, and methods for analyzing and reporting the movements in mechanical structures, inanimate physical structures, machinery, and machine components, including automatically detecting aliased frequencies of a component on the structure which exhibits frequencies higher than the maximum frequency of the FFT spectrum calculated from the acquired data. To automatically detect the presence of aliased frequencies, a second virtually identical recording is acquired using a slightly different sampling rate and this provides the basis for detecting frequencies which are greater than the Nyquist sampling rate of the video recording and calculating the true frequency value of the aliased peaks in the frequency spectrum.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: August 24, 2021
    Assignee: RDI TECHNOLOGIES, INC.
    Inventors: Kenneth Ralph Piety, Jeffrey R. Hay, Mark William Slemp
  • Patent number: 11100631
    Abstract: A surgical image acquisition system includes multiple illumination sources, each source emitting light at a specified wavelength, a light sensor to receive light reflected from a tissue sample illuminated by each of the illumination sources, and a computing system. The computer system may receive data from the light sensor when the tissue sample is illuminated by the illumination sources, determine a depth of a structure within the tissue sample, and calculate visualization data regarding the structure and its depth within the tissue. The visualization data may have a format for use by a display system. The structure may include vascular tissue. The illumination sources may include red, green, blue, infrared, ultraviolet, and white light sources. The structure depth may be determined by a spectroscopy method or a Doppler shift method. The system may include a controller and computer enabled instructions to accomplish the above.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: August 24, 2021
    Assignee: Cilag GmbH International
    Inventors: David C. Yates, Fergus P. Quigley, Frederick E. Shelton, IV, Jason L. Harris, Tamara Widenhouse
  • Patent number: 11095835
    Abstract: An example method and hyperspectral imaging (HSI) system for imaging a scene are provided. The method is for imaging the scene with the HSI system including a sensor with a plurality of sensor pixels and a plurality of spectral filters, each of the spectral filters being associated with one of the sensor pixels. The method comprises obtaining a higher-resolution spatial image by illuminating the scene with a first set of wavelengths, wherein each spectral filter passes the first set of wavelengths to the sensor pixel it is associated with. The method further comprises obtaining a lower-resolution hyperspectral image by illuminating the scene with a second set of wavelengths, wherein each spectral filter passes only a subset of the second set of wavelengths to the sensor pixel it is associated with.
    Type: Grant
    Filed: December 20, 2019
    Date of Patent: August 17, 2021
    Assignee: IMEC VZW
    Inventors: Nicolaas Tack, Andy Lambrechts
  • Patent number: 11094063
    Abstract: A method for monitoring and detecting physical anomalies may include receiving, by a processor and from a camera of a brushing apparatus, an image of a body from a predetermined distance away from the body. The method may further include detecting, by the processor, an atypical contour of the image that indicates a physical anomaly. The method may further include generating, by the processor, a notification in response to detecting the atypical contour that indicates the physical anomaly.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: August 17, 2021
    Assignee: International Business Machines Corporation
    Inventor: Ilse M. Breedvelt-Schouten
  • Patent number: 11092550
    Abstract: The present invention provides a method of using Raman spectroscopy for identification of low grade cervical cytology cases likely to progress to high grade/cancer. The Applicant has found that high quality Raman spectra can be successfully acquired from morphologically normal appearing cells from negative, LSIL and HSIL Thinprep® specimens and different grades of cervical pre-cancer can be separated with good sensitivities and specificities. Raman spectroscopy can further identify different categories of the LSIL cases i.e., whether they are likely to regress to negative or progress to HSIL cytology.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: August 17, 2021
    Assignees: Technological University Dublin, The Provost, Fellows, Foundation Scholars, and the Other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin
    Inventors: Shiyamala Duraipandian, Fiona Lyng, Damien Traynor, John O'Leary, Cara Martin, Padraig Kearney
  • Patent number: 11094104
    Abstract: An information processing device has a computation unit for determining an optimal solution of an external force that minimizes a difference between a surface image of an elastic body captured from at least one direction, and a rendering image as observed from the direction which is generated from a three-dimensional model of the elastic body elastically deformed by an unobserved external force.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: August 17, 2021
    Assignee: KYOTO UNIVERSITY
    Inventor: Megumi Nakao
  • Patent number: 11080528
    Abstract: A brushing apparatus includes a head and a handle extending out from the head. The head includes a plurality of bristles. A camera may be secured to the head of the brushing apparatus adjacent to the plurality of bristles. The system may further include a processor and a memory in communication with the processor. The memory contains instructions that, when executed by the processor, cause the processor to receive an image from the camera as bristles of the plurality of bristles are engaged with a body. Further instructions cause the processor to detect an atypical contour of the image that indicates a physical anomaly. Further instructions cause the processor to generate a notification in response to detecting the atypical contour that indicates the physical anomaly.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: August 3, 2021
    Assignee: International Business Machines Corporation
    Inventor: Ilse M. Breedvelt-Schouten