With Feedback Of Signal To Patient Patents (Class 600/545)
  • Publication number: 20140316230
    Abstract: With explosive penetration of portable electronic devices (PEDs) recent focus into consumer EEG devices has been to bring advantages including localized wireless interfacing, portability, and a low-cost high-performance electronics platform to host the processing algorithms to bear. However, most development continues to focus on brain-controlled video games which are nearly identical to those created for earlier, more stationary consumer EEG devices and personal EEG is treated as of a novelty or toy. According to embodiments of the invention the inventors have established new technologies and solutions that address these limitations within the prior art and provide benefits including, but not limited to, global acquisition and storage of acquired EEG data and processed EEG data, development interfaces for expansion and re-analysis of acquired EEG data, integration to other non-EEG derived user data, and long-term user wearability.
    Type: Application
    Filed: April 22, 2014
    Publication date: October 23, 2014
    Applicant: Personal Neuro Devices Inc.
    Inventors: Steve Denison, Andrew Stephen Faulkner, Tony Gaitatzis, Arwen Moore, Robert Sawatsky, Chad Veinotte, Bruno Daoust, Elliott Alfred Loh
  • Patent number: 8868174
    Abstract: A brain information output apparatus includes an intention determination information storage unit in which two or more pieces of intention determination information can be stored, with each intention determination information including a pair of an intention identifier, and a learning feature amount group including one or more feature amounts extracted from second learning data that is obtained by converting first learning data into intracerebral brain activity data, the first leaning data being acquired from the outside of the cranium of a user when the user performs a trial according to one intention; a first brain activity data acquiring unit that acquires first brain activity data from the outside of the cranium of a user; a second brain activity data acquiring unit that converts the first brain activity data to intracerebral brain activity data, and acquires second brain activity data; a feature amount group acquiring unit that acquires, from the second brain activity data, an input feature amount group
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: October 21, 2014
    Assignees: Honda Motor Co., Ltd., Advanced Telecommunications Research Institute International
    Inventors: Masaaki Sato, Takahito Tamagawa, Okito Yamashita, Yusuke Takeda, Mitsuo Kawato, Kentaro Yamada, Masahiro Kimura, Akihiro Toda, Tatsuya Okabe
  • Patent number: 8862219
    Abstract: A method of creating a user profile for use in a brain computer interface includes performing a training exercise, measuring a user's brain signals during the training exercise, mapping specific signals of the user's brain signals to predefined mental task descriptions, and creating a user profile including the user's brain signals mapped to the mental task descriptions. The user profile so created can be used in a method of creating a brain computer interface for a user for an application. This method includes accessing a user profile including the user's brain signals mapped to mental task descriptions, accessing an application profile including a plurality of properties of the application, matching one or more mental task descriptions from the user profile to a respective property from the application profile, and creating a brain computer interface accordingly.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: October 14, 2014
    Assignee: Koninklijke Philips N.V.
    Inventors: Gary Nelson Garcia Molina, Alphons Antonius Maria Lambertus Bruekers, Marijn Christian Damstra, Johannes Weda
  • Patent number: 8855758
    Abstract: An apparatus for obtaining EEG data includes a signal processing component for receiving EEG signals from each of a plurality of electrodes and a data output component. The signal processing component is arranged to convert respective EEG signals in real time to a reduced data set and provide the reduced data set to the data output component.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: October 7, 2014
    Assignee: Imperial Innovations Limited
    Inventors: Esther O. Rodriquez-Villegas, David C. Yates
  • Patent number: 8851073
    Abstract: A medical device may include a patient interface for use in a breathing assistance system, an electronic device coupled to the patient interface, and one or more electrical conductors at least partially integrated with the patient interface. The patient interface may include a connection end configured for receiving gas communicated by a gas delivery apparatus, and a patient end configured for insertion into or more breathing passageways of a patient. The one or more electrical conductors at least partially integrated with the patient interface may be capable of facilitating communication of electrical signals between the electronic device and the gas delivery apparatus when the patient interface is communicatively coupled to the gas delivery apparatus.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: October 7, 2014
    Assignee: Covidien LP
    Inventor: Joseph Douglas Vandine
  • Patent number: 8838225
    Abstract: The present invention introduces a method for processing multichannel measurement data achieved especially in MEG and EEG measurements. The method uses a signal space separation (SSS) method and the orthogonality of lead fields in order to calculate linear transformation from physical measurement channels to virtual channels. The geometry related to the measurement arrangement is dissipated and the number of virtual channels is clearly lower than the number of physical sensors. The concept of total information can be applied for such transformed measurement data due to orthogonality. The method offers simplified post-processing of the biomagnetic data, such as for source modelling. The total information can also be interpreted as a robust quantity describing the physiological state of a patient.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: September 16, 2014
    Assignee: Elekta AB (publ)
    Inventors: Antti Ahonen, Matti Kajola, Jukka Nenonen, Juha Simola, Samu Taulu
  • Patent number: 8825149
    Abstract: Certain examples provide a method of collecting and analyzing complex auditory brainstem response. The example method includes presenting at least one complex auditory stimulus to a subject and acquiring the subject's complex auditory brainstem response. The example method includes averaging complex auditory brainstem responses from the subject in at least one of a time domain and a frequency domain to form a collected response. The example method includes analyzing the collected response using a signal processor to process the collected response to provide a processed output and to adapt the response for comparison to the at least one complex auditory stimulus. The example method includes performing statistical computations on the processed output to generate visual and data feedback for a user.
    Type: Grant
    Filed: January 31, 2012
    Date of Patent: September 2, 2014
    Assignee: Northwestern University
    Inventors: Nina Kraus, Trent G. Nicol, Erika E. Skoe
  • Patent number: 8818498
    Abstract: An eyeglass-type electroencephalogram interface system is worn on the head of a user. The system includes: an output section for presenting a visual stimulation to the user; an ear electrode portion disposed at a position coming in contact with an ear of the user when the system is worn; a facial electrode portion disposed at a position coming in contact with the face below a straight line connecting an external canthus and an internal canthus of an eye of the user, such that the mass of the system is supported at the position, when the system is worn; and an electroencephalogram measurement and determination section for measuring an event-related potential on the basis of a potential difference between the ear electrode portion and the facial electrode portion based on the visual stimulation being presented by the output section as a starting point.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: August 26, 2014
    Assignee: Panasonic Corporation
    Inventors: Yoshihisa Terada, Koji Morikawa
  • Patent number: 8818497
    Abstract: It is an object to provide a means for easily operating various devices to be controlled (i.e. a word processor or a car) using a brain wave signal of a patient with Alzheimer's disease or a psychological disorder, and for supporting the active performance of a user by employing wireless communication with a memory (wireless memory) capable of communicating without wires in which a command on the human movement is memorized. A present biological signal processing unit has an electrode for detecting a biological signal (an electric signal) from a living body, or for transmitting an electric signal into a living body, an interface, and an antenna which can communicate with an external device (i.e. wireless memory, reader/writer); therefore, convenience of the user is improved in the case where a user utilizes an electronic device or the like. In addition, the active performance of a user can be supported.
    Type: Grant
    Filed: July 12, 2005
    Date of Patent: August 26, 2014
    Assignee: Semiconductor Energy Laboratory Co., Ltd.
    Inventor: Shunpei Yamazaki
  • Patent number: 8818502
    Abstract: A method and device for endocrine and exocrine gland control. The method comprises selecting neuro-electrical coded signals from a storage area that are representative of body organ function. The selected neuro-electrical coded signals are then transmitted to a treatment member, which is in direct contact with the body, and which then broadcasts the neuro-electrical coded signals to a specific endocrine and exocrine gland nerve or gland to modulate the gland functioning. A control module is provided for transmission to the treatment member. The control module contains the neuro-electrical coded signals which are selected and transmitted to the treatment member, and computer storage can be provided for greater storage capacity and manipulation of the neuro-electrical coded signals.
    Type: Grant
    Filed: September 2, 2009
    Date of Patent: August 26, 2014
    Assignee: Codes of Life, LLC
    Inventor: Eleanor L. Schuler
  • Patent number: 8812098
    Abstract: In some examples, systems, devices, and techniques for determining a particular sleep stage of a patient, determining a seizure state of the patient during the particular sleep stage, and generating a seizure probability metric for the particular sleep stage based on the sleep stage and seizure state are described. In some cases, a patient may be more susceptible to seizure events during particular sleep stages. One or more seizure probability metrics indicative of a patient's susceptibility to seizure events during a particular sleep stage may be useful in creating a patient-specific treatment regimen.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: August 19, 2014
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Jianping Wu, Dwight E. Nelson
  • Publication number: 20140228702
    Abstract: A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.
    Type: Application
    Filed: April 17, 2014
    Publication date: August 14, 2014
    Applicant: Elminda Ltd.
    Inventors: Goded SHAHAF, Amir B. Geva, Tomer Carmeli, Noga Pinchuk, Israel Tauber, Amit Reches, Guy Ben-Bassat, Ayelet Kanter, Urit Gordon
  • Publication number: 20140213926
    Abstract: In some examples, a processor is configured determine whether efficacy of therapy delivered by a medical device to the patient may have changed and generate a notification based on the determination. For example, a processor may be configured to determine whether a bioelectrical brain signal indicative of activity of a brain of a patient includes a biomarker that indicates efficacy of therapy delivered by a medical device to the patient may have changed, and generate notification based on determining the bioelectrical brain signal includes the biomarker. In some examples, the processor modifies the therapy delivered to the patient prior to generating the notification.
    Type: Application
    Filed: January 25, 2013
    Publication date: July 31, 2014
    Applicant: MEDTRONIC, INC.
    Inventor: Janardan Vaidyanathan
  • Patent number: 8792976
    Abstract: Artificial control of a prosthetic device is provided. A brain machine interface contains a mapping of neural signals and corresponding intention estimating kinematics (e.g. positions and velocities) of a limb trajectory. The prosthetic device is controlled by the brain machine interface. During the control of the prosthetic device, a modified brain machine interface is developed by modifying the vectors of the velocities defined in the brain machine interface. The modified brain machine interface includes a new mapping of the neural signals and the intention estimating kinematics that can now be used to control the prosthetic device using recorded neural brain signals from a user of the prosthetic device. In one example, the intention estimating kinematics of the original and modified brain machine interface includes a Kalman filter modeling velocities as intentions and positions as feedback.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: July 29, 2014
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Vikash Gilja, Paul Nuyujukian, Cynthia A Chestek, John P Cunningham, Byron M. Yu, Stephen I Ryu, Krishna V. Shenoy
  • Patent number: 8792973
    Abstract: Apparatus for providing an interface between a nerve and an external information system. The apparatus includes a substrate having a first surface, an opposite second surface, and an electrode body, wherein the electrode body includes a plurality of holes extending therethrough. The apparatus also includes a plurality of electrical leads embedded within the substrate and a plurality of ring electrodes, wherein each of the ring electrodes circumscribes a corresponding hole, and wherein at least a portion of the ring electrodes is positioned on each of the first surface and the second surface.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: July 29, 2014
    Assignee: Washington University
    Inventors: Daniel Moran, Blaine Christiansen, Matthew MacEwan
  • Patent number: 8786546
    Abstract: A method for activating an operational mode change of a device. The method includes flashing at least one indicator, wherein each of the at least one indicator flashes at a particular initial frequency. The method also includes receiving electroencephalograph (EEG) data from an EEG device of a user. The method further includes recognizing a portion of the received EEG data to substantially match activation EEG data, wherein the activation EEG data corresponds to predicted or recorded EEG data of the user in observance of one of the at least one indicator flashing at the particular initial frequency. The method additionally includes activating an operational mode change for providing power to a display upon recognizing the portion of the received EEG data to substantially match the activation EEG data.
    Type: Grant
    Filed: August 10, 2012
    Date of Patent: July 22, 2014
    Assignee: Rockwell Collins, Inc
    Inventors: John Bendickson, Maury Anderson
  • Patent number: 8788030
    Abstract: Systems, methods, and apparatus for neuro-robotic tracking point selection are disclosed. A described example robot control system includes a feature and image presenter, a classifier, a visual-servo controller, and a robot interface. The feature and image presenter is to display an image of an object, emphasize one of more potential trackable features of the object, receive a selection of the emphasized feature, and determine an offset from the selected feature as a goal. The classifier is to classify a mental response to the emphasized features, and to determine that the mental response corresponds to the selection of one of the emphasized features. The visual-servo controller is to track the emphasized feature corresponding to an identified brain signal. The robot interface is to generate control information to effect a robot action based on the emphasized feature, the visual-servo controller to track the emphasized feature while the robot action is being effected.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: July 22, 2014
    Assignee: HRL Laboratories, LLC
    Inventors: David W. Payton, Michael J. Daily
  • Publication number: 20140194726
    Abstract: Disclosed are methods and systems for non-invasive neuromodulation using ultrasound for cognitive enhancement. Cognitive enhancement can be used for mitigation of abnormal conditions such as Alzheimer's Disease, Parkinson's Disease or stroke, or for enhancement in a normal individual. The neuromodulation can produce acute or long-term effects. The latter occur through Long-Term Depression (LTD) and Long-Term Potentiation (LTP) via training. Included is control of direction of the energy emission, intensity, frequency, pulse duration, pulse pattern, mechanical perturbation, and phase/intensity relationships to targeting and accomplishing up regulation and/or down regulation.
    Type: Application
    Filed: January 4, 2013
    Publication date: July 10, 2014
    Applicant: Neurotrek, Inc.
    Inventors: David J. MISHELEVICH, Daniel Z. WETMORE, William J. TYLER, Tomo SATO
  • Patent number: 8774910
    Abstract: A polymer linear actuator for a micro electro mechanical system (MEMS) and a micro manipulator for a measurement device of cranial nerve signal using the same are provided. The polymer linear actuator has first and second bodies positioned spaced apart to a distance from each other, and one or more pairs of V-type moving units connecting the first and second bodies together, wherein the moving units in pair are opposed to each other to convert a rotation motion of the respective moving units into a linear motion, thereby causing the first and second bodies to move linearly.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: July 8, 2014
    Assignee: Korea Institute of Science and Technology
    Inventors: Suk-ho Park, Jin-seok Kim, Ju-hee Hong, Sung-wook Yang, Hee-sup Shin, Dong-won Lee, Suk-chan Lee, Hui-su Kim, Eui Sung Yoon
  • Patent number: 8768447
    Abstract: The invention relates to processing of physiological signal data in patient monitoring. In order to alleviate the problems caused by suppression waveforms in the analysis of physiological signal data, measurement data is derived from a segment of the time series of physiological signal data and valid measurement data is collected from the derived measurement data, thereby to form a set of valid measurement data. The collecting includes selecting measurement data that fulfills at least one predetermined threshold condition. Furthermore, at least a portion of the set of valid measurement data is supplied to a further processing stage when the amount of collected measurement data in the set is at least at a predetermined level. The deriving and collecting may be repeated for consecutive segments of the time series, in which case the supplying is performed for at least some of the consecutive segments of the time series.
    Type: Grant
    Filed: January 9, 2007
    Date of Patent: July 1, 2014
    Assignee: General Electric Company
    Inventors: Miikka Ermes, Mika Särkelä
  • Patent number: 8768449
    Abstract: Prosthetic devices, methods and systems are disclosed. Eye position and/or neural activity of a primate are recorded and combined. The combination signal is compared with a predetermined signal. The result of the comparison step is used to actuate the prosthetic device.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: July 1, 2014
    Assignee: California Institute of Technology
    Inventors: Bijan Pesaran, Richard A. Andersen
  • Patent number: 8761868
    Abstract: A medical device system for comparing a cardiopulmonary signal to a brain signal. In one embodiment of the invention, a medical device system is provided that includes a brain monitoring element, respiratory monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a respiratory signal from the respiratory monitoring element. The processor is further configured to compare the brain signal to the respiratory signal. Methods of comparing a brain signal to a cardiopulmonary signal are also provided.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: June 24, 2014
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves
  • Publication number: 20140171757
    Abstract: A training apparatus 1000 using a method of decoding nerve activity includes: a brain activity detecting device 108 for detecting brain activity at a prescribed area within a brain of a subject; and an output device 130 for presenting neurofeedback information (presentation information) to the subject. A processing device 102 decodes a pattern of cranial nerve activity, generates a reward value based on a degree of similarity of the decoded pattern with respect to a target activation pattern obtained in advance for the event as the object of training, and generates presentation information corresponding to the reward value.
    Type: Application
    Filed: October 31, 2012
    Publication date: June 19, 2014
    Applicant: ADVANCED TELECOMMUNICATIONS RESEARCH INSTITUTE INTERNATIONAL
    Inventors: Mitsuo Kawato, Takeo Watanabe, Kazuhisa Shibata, Yuka Sasaki
  • Patent number: 8755879
    Abstract: Analog electrical and pressure data obtained by an EEG/pressure sensor matrix from the subject are sent to a signal processing module that derives digital EEG data from the electrical signal and pressure data without using sensors attached to a subject's head. The pressure data are used as a secondary signal to measure the physical orientation of the subject's head. The physical orientation is used to transform the derived EEG signal to a known coordinate axis (the orientation of the subject's head) to obtain useful, consistent, and accurate EEG data. The EEG may be used to determine a sleep state of a subject and to awaken the subject while in a particular state.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: June 17, 2014
    Assignee: Forty Winks, LLC
    Inventors: Zimin Hang, James Nolan Tin Ahad, Xiaoyang Ye, Daniel Alexander Corin
  • Publication number: 20140163410
    Abstract: A neurofeedback system for providing neurofeedback to at least one patient. The neurofeedback system includes: EEG head sensors; a central server to store treatment protocol algorithm(s) provided via the Internet; and a data collection module associated with a computer-based device. The data collection module: transmits the EEG brain activity to the central server via the Internet by way of the computer-based device; provides feedback to the patient; and receives a treatment protocol from the central server via the Internet by way of the computer-based device.
    Type: Application
    Filed: October 8, 2013
    Publication date: June 12, 2014
    Inventor: Rivka SELA
  • Patent number: 8751160
    Abstract: Mobile clinicians conduct in-home patient visits utilizing on-site diagnostic and treatment equipment, where service is enhanced by the use of portable computing and communications equipment. A mobile care entity provides mobile clinicians preprogrammed portable computers. Each portable computer updates patient data in the local storage utilizing a wireless communications device to download updates from a central storage facility. The entity selects a mobile clinician and dispatches him/her to the patient's premises. The clinician visits the patient's premises accompanied by an assortment of electronic diagnostic and treatment devices. The mobile clinician utilizes various diagnostic devices to prepare machine-readable reports of related aspects of the patient's condition.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: June 10, 2014
    Inventor: C. Gresham Bayne
  • Patent number: 8750957
    Abstract: An embodiment of the invention provides a neural probe containing a plurality of nanoscale recording electrodes. The recording electrodes have a width of 1 micron or less and a distance between adjacent recording electrodes is 10 microns or less. Another embodiment of the invention provides a neural probe comprising a plurality of microfabricated recording electrodes located on a polymer base material, such as a flexible polymer cantilever.
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: June 10, 2014
    Assignee: California Institute of Technology
    Inventors: Hongxing Tang, Michael L. Roukes, Richard Renaud
  • Patent number: 8744562
    Abstract: A medical device system that includes a brain monitoring element, cardiac monitoring element and a processor. The processor is configured to receive a brain signal from the brain monitoring element and a cardiac signal from the cardiac monitoring element. The processor is further configured to compare the brain signal to the cardiac signal. A method of comparing a brain signal to a cardiac signal is also provided.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: June 3, 2014
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves
  • Publication number: 20140148657
    Abstract: A system and method are presented for use in monitoring brain activity of a subject. The system comprises a control unit which comprises: a data input utility for receiving measured data comprising data corresponding to signals measured during a certain time period and being indicative of a subject's brain activity originated from locations in the subject's brain during said certain time period, and a processor utility which is configured and operable for processing the measured data and generating data indicative thereof in the form of a multi-parameter function presenting a relation between frequency and time data of the measured signals and for analyzing said relation and identifying a subject-related signature corresponding to the subject's brain neural activity.
    Type: Application
    Filed: February 2, 2012
    Publication date: May 29, 2014
    Applicants: RAMOOT AT TEL-AVIV UNIVERSITY LTD., The Medical Research,Ifrastructure,AndHealth Services Fund of the TEL AVIV MEDICAL CENTER
    Inventors: Talma Hendler, Nathan Intrator, IIana Klovatch, Sivan Kinreih, Yehudit Meir-Hasson
  • Patent number: 8731650
    Abstract: An EEG cap (8) having 64 or 128 electrodes (10) is placed on the head of the subject (11) who is viewing CRT monitor (14). The signals on each channel are amplified by amplifier (17) and sent to an analog-to-digital converter (20). PC (23) captures and records the amplified signals and the signals are processed by signal processing PC (26) performing linear signal processing. The resulting signal is sent back to a feedback/display PC (29) having monitor (14).
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: May 20, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Paul Sajda, Lucas Cristobal Parra
  • Patent number: 8727977
    Abstract: The invention provides a body-worn vital sign monitor that measures a patient's vital signs (e.g. blood pressure, SpO2, heart rate, respiratory rate, and temperature) while simultaneously characterizing their activity state (e.g. resting, walking, convulsing, falling) and posture (upright, supine). The monitor processes this information to minimize corruption of the vital signs and associated alarms/alerts by motion-related artifacts. It also features a graphical user interface (GUI) rendered on a touchpanel display that facilitates a number of features to simplify and improve patient monitoring and safety in both the hospital and home.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: May 20, 2014
    Assignee: Sotera Wireless, Inc.
    Inventors: Matt Banet, Jim Moon, Gunner Trommer, Caroline DiBattista
  • Publication number: 20140135644
    Abstract: A wearable device and a managing device to manage a status of a user, the wearable device including a brainwave measuring sensor to measure a brainwave of the user, an environment information sensor to sense surrounding environment information, a vibrator to generate vibrations, a display device to display a message, a communicator to transmit sensed values of the brainwave measuring sensor and the environment information sensor to an external device and to receive a control signal from the external device, and a controller to control operations of the vibrator and the display device based on at least one of the sensed value of the brainwave measuring sensor, the sensed value of the environment sensor, and the control signal. Therefore, safety of the user is maintained even when the use is in a dangerous situation.
    Type: Application
    Filed: November 14, 2013
    Publication date: May 15, 2014
    Applicant: Samsung Electronics Co., Ltd
    Inventor: Sang-tae KIM
  • Patent number: 8718755
    Abstract: The present invention relates to methods and devices for determining the state of a neural system. In one embodiment, a plurality of stimuli to the system can be delivered to the system, and then the resulting respective responses can be analyzed to determine whether the system state is static, or whether it is undergoing dynamic changes. In another aspect of the invention, a single stimulus having a plurality of components can be administered, and the responses to each component can be contrasted and compared to determine the state of the neural system. In each case, this information can be used to predict the occurrence of neural perturbations or episodes associated with a change in the state of the neural system.
    Type: Grant
    Filed: November 3, 2003
    Date of Patent: May 6, 2014
    Assignee: George Mason Intellectual Properties, Inc.
    Inventors: Bruce Gluckman, Kristen Richardson, Steven Weinstein, Steven Schiff
  • Patent number: 8712514
    Abstract: A system and method of central auditory processing testing and evaluation provides for identifying clinically relevant neural synchrony in the auditory brainstem pathway. The system or method finds use as a tool to evaluate auditory processing disorders, and hence, potential auditory system and/or learning disabilities. The system or method may further find use in the selection and fitting of hearing corrective appliances such as hearing aid or cochlear implant devices and/or in the selection and implementation of auditory training regimens.
    Type: Grant
    Filed: August 25, 2011
    Date of Patent: April 29, 2014
    Assignee: Northwestern University
    Inventors: Trent Nicol, Nina Kraus
  • Patent number: 8708905
    Abstract: A method, device, and computer program product for monitoring the physiological state of a subject is disclosed. A first plurality of physiological signals are acquired from the subject and a second plurality of signal parameters are determined based on the first plurality of physiological signals. Relevant signal information is selected from among the signal information produced and at least one screen page is displayed at a time, thereby to make at least part of the signal information visible to a user. The signal information visible to the user on the at least one screen page may then be revised based on the selection and without user interaction, thereby to accelerate clinical decision-making and to diminish the possibility of undetected changes in the state of the subject.
    Type: Grant
    Filed: June 12, 2009
    Date of Patent: April 29, 2014
    Assignee: General Electric Company
    Inventor: Mika Sarkela
  • Publication number: 20140114207
    Abstract: A cognitive management method and system that monitors and manipulates a response signal from a neurological organ to optimize cognitive performance and behavioral management of the neurological organ. The method allows a user to transmit a stimulus signal such as optical or auditory to the organ and receive a return signal in response. A sensor, such as EEG electrodes detects the response signal. The response signal generated by the neurological organ is then detected by the sensor and transmitted to data storage. The signal can be reconfigured and retransmitted to a display device. The signal includes Hertz and real time frequencies. The signal includes a signal parameter with a high range and a low range. An alert actuates when the signal exceeds the parameter. The signal is monitored by the user and invited followers to analyze and treat cognitive performance and behavior.
    Type: Application
    Filed: October 18, 2012
    Publication date: April 24, 2014
    Inventor: Timothy Patterson
  • Patent number: 8700142
    Abstract: A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians' offices, detects and amplifies brain waves and converts then into digital data for analysis by comparison with data from normal groups. In one embodiment, the EEG electrodes are in a headband which broadcasts the data, by radio or cellular phone, to a local receiver for re-transmission and/or analysis. In another embodiment, the subject is stimulated in two modes, i.e., aural and sensory, at two different frequencies to provide the subject's EPs (Evoked Potentials), assessing transmission through the brainstem and thalamus.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: April 15, 2014
    Assignee: New York University
    Inventors: Erwin Roy John, Michael Sasha John
  • Patent number: 8694087
    Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: April 8, 2014
    Assignee: Cornell University
    Inventor: Nicholas D. Schiff
  • Patent number: 8692677
    Abstract: Disclosed herein is a wake-up assisting apparatus including: an electrode which comes into contact with the parietal of the human body; a signal processing part which detects brain waves through the electrode, determines the sleep stage from the thus detected brain waves, and decides the wake-up time according to the sleep stage; and a stimulating part which gives stimuli to the human body at the wake-up time.
    Type: Grant
    Filed: November 4, 2011
    Date of Patent: April 8, 2014
    Assignee: Sony Corporation
    Inventors: Seiji Wada, Takuro Yamamoto
  • Patent number: 8688209
    Abstract: A device for ambulatory monitoring of brain activity includes a patch secured to a head of a monitoring subject and an electrode secured to the head of the monitoring subject. The electrode produces a signal indicating brain activity of the monitoring subject. The device further includes a signal processor that receives the signal produced by the electrode and processes the signal to produce data. The signal processor is secured to the monitoring subject. The device further includes a display that displays the data produced by the signal processor, the display being secured to the monitoring subject. The device also includes a power source secured to the monitoring subject, the power source providing power to the electrode, the signal processor, and the display wherein the monitoring subject may ambulate unimpeded by the patch, the electrode, the signal processor, the display and the power source.
    Type: Grant
    Filed: September 19, 2007
    Date of Patent: April 1, 2014
    Assignee: Koninklijke Philips N.V.
    Inventor: Evgeny Verbitskiy
  • Patent number: 8670821
    Abstract: An electroencephalogram signal processing method includes a recording step, a retrieving step, a removing step and a synthesizing step. The recording step retrieves EEG signal components of a testee via a plurality of electrodes, wherein the EEG signal components serve as an input signal. The retrieving step filters the input signal to obtain a predetermined frequency band signal, and subtracts the predetermined frequency band signal from the input signal to obtain a difference signal. The removing step performs an independent component analysis operation between the difference signal and a separating matrix to obtain an analysis signal, generates a separating pseudo inverse and an independent analysis signal, and performs a matrix operation between the separating pseudo inverse and the independent analysis signal to obtain a corrected signal. The synthesizing step adds the corrected signal and the predetermined frequency band signal together to obtain an output signal.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: March 11, 2014
    Assignee: I-Shou University
    Inventors: Ching-Tai Chiang, Rong-Ching Wu, Chen-Sen Ouyang, Li-Ju Huang, Rei-Cheng Yang
  • Patent number: 8670830
    Abstract: Bioelectrical signals may be sensed within a brain of a patient with a plurality of sense electrode combinations. A stimulation electrode combination for delivering stimulation to the patient to manage a patient condition may be selected based on the frequency band characteristics of the sensed signals. In some examples, a stimulation electrode combination associated with the sense electrode combination that sensed a bioelectrical brain signal having a relatively highest relative beta band power level may be selected to deliver stimulation therapy to the patient. Other frequency bands characteristics may also be used to select the stimulation electrode combination.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: March 11, 2014
    Assignee: Medtronic, Inc.
    Inventors: David L. Carlson, Randy M. Jensen, Timothy J. Denison, Jianping Wu, Gabriela C. Molnar, Scott R. Stanslaski, William J. Marks, Jr.
  • Patent number: 8665311
    Abstract: Improved methods and apparatus for sharing and collaborating around a video source by maintaining and providing to users a list of a plurality of contacts containing both video source device contacts and interactive message source contacts. This allows for collaboration among users by permitting them to communicate with each other around an automatically-shared video source, to interact with automatically shared video sources, and to make decisions based on these shared video sources.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: March 4, 2014
    Assignee: vBrick Systems, Inc.
    Inventors: Erik Herz, Douglas Uhl
  • Patent number: 8655438
    Abstract: An EEG monitoring device, contains at least one electrode, a non-linear analog signal processor, a variable resolution analog-to-digital converter, a storage, and a power source. The non-linear analog signal processor receives a signal from the at least one electrode and determines whether the signal is within a significant category. The variable resolution analog-to-digital converter converts signals received from the non-linear analog signal processor into high-resolution digital signals if the signals are within the significant category, and converts signals received from the non-linear analog signal processor at a low resolution if the signals are not within the significant category. The storage stores high-resolution digital signals received from the variable resolution analog-to-digital converter and the power source is connected to, and provides power to, the non-linear analog signal processor, the variable resolution analog-to-digital converter, and the storage.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: February 18, 2014
    Assignee: Dartmouth College
    Inventor: Kofi Odame
  • Patent number: 8655441
    Abstract: In an exemplary implementation of this invention, a user wears comfortable biosensors. These sensors gather physiological data from the user and transmit this data to another radio-enabled device. This other device may be a mobile phone. The data is further transmitted, via this other radio-enabled device, to one or more networks (such as wireless networks or the Internet). A processor analyzes this transmitted data, in real time, to recognize patterns in the data that indicate the need for therapeutic intervention. Upon recognition of such a pattern, the processor outputs instructions for a transducer to deliver therapeutic stimuli. These instructions are transmitted, over one or more wired or wireless networks, to a transducer which delivers the therapeutic stimuli to the user.
    Type: Grant
    Filed: July 13, 2010
    Date of Patent: February 18, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Richard Fletcher, Rosalind Picard, Hoda Eydgahi, Clayton Williams
  • Publication number: 20140031712
    Abstract: A system for detecting a neurological deterioration in a patient, the system constituted of: an analyzing module; and at least one input port arranged to receive a plurality of first samples of electroencephalographic (EEG) activity of the patient and a plurality of second samples of EEG activity of the patient and further arranged to output the received samples to the analyzing module, wherein the analyzing module is arranged to: compare a function of the received first EEG samples to a function of the received second EEG samples; determine the difference between the outcome of the comparison and a baseline value; and output a neurological deterioration signal responsive to the determined difference.
    Type: Application
    Filed: April 5, 2012
    Publication date: January 30, 2014
    Applicant: NEUROKEEPER TECHNOLOGIES LTD.
    Inventors: Moshe Herskovitz, Goded Shahaf
  • Patent number: 8639329
    Abstract: Disclosed are apparatus and methods that provide the ability to electrical stimulate a physical system, and actively eliminate interference with signal acquisition (artifacts) that arises from the stimulation. The technique implemented in the circuits and methods for eliminating interference connects a discharge path to a physical interface to the system to remove charge that is built-up during stimulation. By placing the discharge path in a feedback loop that includes a recording preamplifier and AC-coupling circuitry, the physical interface is brought back to its pre-stimulation offset voltage. The disclosed apparatus and methods may be used with piezoelectric transducers, ultrasound devices, optical diodes, and polarizable and non-polarizable electrodes. The disclosed apparatus can be employed in implantable devices, in vitro or in vivo setups with vertebrate and invertebrate neural tissue, muscle fibers, pancreatic islet cells, osteoblasts, osteoclasts, bacteria, algae, fungi, protists, and plants.
    Type: Grant
    Filed: August 29, 2006
    Date of Patent: January 28, 2014
    Assignee: Georgia Tech Research Corporation
    Inventors: Edgar A. Brown, James D. Ross, Richard A. Blum, Stephen P. DeWeerth
  • Patent number: 8639320
    Abstract: A muscle-activity diagnosis apparatus includes: an acquiring section acquiring a myoelectric signal from a test subject; using the myoelectric signal as an original signal, a transformed-signal generating section generating a transformed signal by performing Hilbert transformation and inverse Fourier transformation on the original signal; a phase-velocity calculation section calculating a phase velocity of the myoelectric signal on the basis of phases of the original signal and the transformed signal; and on the basis of a plurality of feature quantities of a waveform of the myoelectric signal in a unit time and the plurality of feature quantities including at least a size of amplitude of the myoelectric signal and the calculated phase velocity, a state-identifying section identifying an activity state of a muscle of a predetermined part of a body of the test subject for each of the unit time.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: January 28, 2014
    Assignee: Sony Corporation
    Inventors: Takashi Tomita, Akane Sano, Haruo Oba
  • Patent number: 8628472
    Abstract: A method and device for warning diabetics of imminent hypoglycaemic attacks. EEG signals are collected from a person using subcutaneously placed electrodes and the signals are led via wires drawn under the person's skin to a subcutaneously placed signal interface unit from where they are transmitted to an externally worn signal processing unit. The signal processing analyzes the EEG signals and when the pre-seizure characteristics signal changes are detected, a warning signal is given to the person from an alarm giver built into the signal processing unit, e.g., in form of a vibrator. When a person detects a warning signal, the person can prevent the hypoglycaemic attack by, e.g., consuming a sugary food.
    Type: Grant
    Filed: February 16, 2012
    Date of Patent: January 14, 2014
    Assignee: Hypo-Safe A/S
    Inventor: Henning Beck-Nielsen
  • Publication number: 20130338449
    Abstract: An electroencephalogram (EEG) utilizing epileptiform activity detection, warning and recording system adapted for use by non-healthcare professionals or healthcare professionals. The system is simple enough for use by untrained personnel and will be self-contained, not requiring technical setup or point of use maintenance. The system includes a small number of passive or active scalp electrodes for capturing the electrical signals in the subject's brain allowing for detection of epileptiform activity. The system will recognize epileptiform activity and will either transmit signals upon detection of epileptiform activity to either a localized warning device or to a cellular or radio receiving device. The system will note epileptiform activity in a recording component and allow for review of the epileptiform data to allow non-clinical and clinical personnel to verify such activity.
    Type: Application
    Filed: August 15, 2013
    Publication date: December 19, 2013
    Applicant: GLKK, Inc.
    Inventors: David G. Warwick, Jeff Kane, Mark Robert Lee, Sean Kelley, Thomas Lee Gardner