Abstract: Methods, systems, and computer readable media for transoral lung access. In some examples, the system includes a bronchoscope, a concentric tube probe deployable from within the bronchoscope, and a steerable needle nested deployable from within the concentric tube probe. The system can include a control system for deploying the concentric tube probe from the bronchoscope into a lung to a location where a target is within a range of the steerable needle and for deploying the steerable needle from the location to the target.

Abstract: A minimally invasive surgical instrument includes a first mechanism including a periphery and an opening in the periphery, a second mechanism including a surface and a helical slot in the surface, a pin extending through the opening of the first mechanism and into the helical slot of the second mechanism, and a surgical device coupled to an end of the first mechanism. A first axial axis of rotation is defined for the first mechanism. A second axial axis of rotation is defined for the second mechanism. The second axial axis of rotation is coincident with the first axial axis of rotation. Rotation of the first mechanism relative to the second mechanism results in motion of the second mechanism along the second axial access of rotation relative to the first mechanism.

Abstract: A transperineal biopsy guide including a guide member and a displacement member supported by the guide member. The guide member may be configured to operably couple with the transrectal probe and may include a distal end, a proximal end opposite the distal end, and a length extending along a longitudinal axis between the distal and proximal ends. The displacement member may be configured to support the access needle and displace the access needle along at least a portion of the length of the guide member between the distal and proximal ends. The access needle may extend into the subcutaneous tissue when the access needle is displaced to the distal end.

Abstract: A platform device for material excision or removal from vascular structures for either handheld or stereotactic table use may comprise a work element or elements configured to selectively open and close at least one articulable beak or scoopula configured to penetrate and remove intra-vascular materials or obstructions, or follow a central lumen of another device or over a wire in a longitudinal direction. Flush and vacuum tissue transport mechanisms may be incorporated. A single tube or an inner sheath and an outer sheath which may be co-axially disposed relative to a work element may be configured to actuate a beak or beaks or scoopulas and provisions for simultaneous beak or scoopula closing under rotation may be incorporated.

Abstract: A uterine manipulator can include a shaft including a first end, a second end, and embodiments of a cutting head configured and arranged to receive a cervix. The cutting head can be configured and adapted to be used to cut the tissue joining the vaginal wall to the cervix and uterus to facilitate removal of the uterus in a minimally invasive manner.

Abstract: Exemplary embodiments of apparatus and method for harvesting small portions of tissue (“micrografts”) to form grafts can be provided. For example, a hollow tube can be inserted into tissue at a donor site, where a distal end of the hollow tube can have two or more points or extensions to facilitate separation of the micrografts from the surrounding tissue. The exemplary apparatus can be provided that includes a plurality of such tubes for simultaneous harvesting of a plurality of micrografts. The harvested micrografts can have a small dimension, e.g., less than about 1 mm, or less than about 0.3 mm, which can promote healing of the donor site and/or viability of the harvested tissue. The micrografts can be approximately cylindrical or strip-shaped, and can be placed in a biocompatible matrix to form a graft or directly into tissue at the recipient site. Such exemplary micrografts can be obtained from skin or other types of tissue, e.g., various internal organs.

Abstract: Drivers and drive systems (e.g., off-axis drive systems, pneumatic motors, multi-gear drive systems, and/or the like), and kits comprising drivers with drive systems, for example, configured to move a drive shaft.

Abstract: A control instrument 100 for a guidewire comprising a first component moveable from a first position, in which the guidewire can move axially relative to the first component, to a second position in which the guidewire is fixed relative to the first component and a second, rotatable, component, wherein rotation of the second component causes the first component to move axially, only when the first component is in its second position, thereby moving the guidewire move axially.

Abstract: A surgical device for use in removing a lesion from a brain includes a first tube, a second tube disposed within the first tube, a sleeve that encloses a portion of the first tube, wire loops attached to a distal end of the first tube, a loop expander and rotation mechanism drivingly coupled with the wire loops, an aspiration port, and an irrigation port. The loop expander and rotation mechanism is operable to expand the wire loops while rotating the wire loops relative to the first tube and contract the wire loops while rotating the wire loops relative to the first tube. Cut tissue is aspirated via the aspiration port. Irrigation fluid is supplied to irrigate the cut tissue via the irrigation port.

Abstract: Disclosed herein is a lifting surgical instrument having a branch point, which is used to insert a thread without a cog and a barb into the skin. The lifting surgical instrument includes a sheath, including: a probe part formed in the tubular shape in which a through hole penetrating in a longitudinal direction is formed, and configured such that the front end thereof may be inserted into the skin; and a body configured to extend from the rear end of the probe part, to have a diameter larger than that of the through hole, to communicate with the through hole, and to include a sheath hole. In this case, a direction guidance portion is provided on the inner surface of the probe part, and the angle at which the needle travels is changed via the direction guidance portion when the needle passes through the through hole.

Abstract: Techniques are disclosed for preparing a repeat intervention on the skin of a patient. This may include acquiring first image data of an intervention region during a first intervention on the skin of the patient. At least two landmarks may be identified on the skin of the patient on the basis of the acquired first image data. A position of the first intervention is then determined with the aid of the landmarks as reference points. In addition, the position of the first intervention and of the landmarks may be stored in a data memory unit. A position of the second intervention is subsequently localized on the basis of the stored position and of the at least two landmarks.

Abstract: An impact or extension handle for a needle assembly such as a jamshidi needle can include an attachment portion and a handle portion. The impact or extension handle can also include an impact strikeplate. The attachment portion is configured to couple to the jamshidi needle. A user can use the impact or extension handle to manipulate the position or angle of the needle assembly. A user can tap a mallet or similar instrument on the impact strikeplate to drive the needle assembly into a target location in a patient's body. The impact or extension handle can allow the user to hold his or her hands out of the way of equipment used during the procedure and away from potentially harmful radiation from imaging equipment used during the procedure.

Abstract: An apparatus comprises an end effector, a body assembly, a power source, and a control module. The end effector is operable for use in a surgical procedure and can deliver energy to a surgical site. The end effector comprises at least one sensor. The sensor is able to measure at least one physical characteristic associated with the surgical site. The body assembly is in communication with the end effector. The power source is in communication with the body assembly and is operable to deliver power to the end effector. The control module is in communication with the sensor and is operable to change delivery of power to the end effector based on data from the sensor indicating a change in tissue density.

Abstract: A tympanostomy tube delivery device comprises a body, a cannula extending distally from the body, and a cylindraceous member disposed within the cannula. The cylindraceous member comprises a tubular portion and a plurality of leaves positioned at the distal end of the tubular portion. The leaves are movable between a collapsed position and an expanded position. The cylindraceous member is slidable relative to the cannula to selectively expose the leaves relative to the open distal end of the cannula. A first leaf of the plurality of leaves has a sharp distal point configured to pierce a tympanic membrane and a longitudinally extending sharp edge. The cylindraceous member may be used to create and dilate a myringotomy incision in a tympanic membrane. The tympanostomy tube delivery device may then be used to deploy a tympanostomy tube through the myringotomy incision.

Abstract: A cutting device is provided that includes an outer tube. The outer tube includes an inner surface defining a passageway. An inner tube is movably disposed in the passageway such that a distal end of the inner tube extends beyond a distal end of the outer tube. The distal end of the inner tube includes a first cutting element. An inner surface of the inner tube defines a lumen. A shaft is slidably disposed in the lumen. The shaft has a distal end including a second cutting element. A deployment mechanism is coupled to a proximal end of the outer tube. The deployment mechanism includes a body, a push button disposed within the body and a collar disposed about the body. The shaft is fixed relative to the collar and the inner tube is fixed relative to the push button. Systems and methods are disclosed.

Abstract: Devices and methods for delivering fluid to the nasal cavity that include a delivery tube and cap configured to be connected to a container that houses the fluid. The delivery tube includes an inner cannula that is positioned within an outer cannula. Each of the cannulas includes a first outlet with one or more openings aligned along a first lateral section and a second outlet with one or more openings aligned along a second lateral section. The cap is configured to secure the delivery tube to the container. The delivery tube and cap are configured to provide relative axial movement between the cannulas. The cannulas are positionable between a first axial position that aligns the first outlets along the first lateral section of the delivery tube to deliver the fluid to a first portion of the nasal cavity, and a second axial position that aligns the second outlets along the second lateral section to deliver fluid to a second portion of the nasal cavity.

Abstract: The present invention comprises methods and devices comprising a scraping element used to contact circumferentially and longitudinally the surface walls of the uterine cavity to provide for broad contact of the intended surface with the device, resulting in attainment of a sufficient volume and comprehensive tissue sample for analysis as an endometrial biopsy or screening uterine cancer. The device may provide for a reservoir for the obtained sample to be contained when removing from the uterine cavity, cervical canal, and vagina. The device may be comprised of a detachable means or be of a material that allows the user to cut the sampling head of the device for placement in collection means to maximize the amount of tissue or cells being sent to the laboratory for analysis.

Abstract: Systems and methods are configured to treat a tissue by automatically linearly oscillating an instrument into a target site. A system may include a body having a length and configured to receive a portion of the instrument guide member having an exposed end and/or an instrument. The system may further include an actuator member disposed within the body and configured to linearly oscillate the instrument within the instrument guide member a fixed distance past the exposed end. The systems and methods can increase patient comfort while empowering clinicians by simplifying interventions for musculoskeletal disorders.

Abstract: A cannula assembly including a cannula and a stylet that is removably fitted in the cannula. A lock selectively holds the stylet to the cannula so the stylet rotates in unison with the cannula. The lock is configured so that the force applied to release the lock results in the subsequent rotation of the stylet relative to the cannula. Methods of disengaging a lock assembly releasably coupling a stylet handle secured to a stylet and a cannula handle secured to a cannula are also provided.

Abstract: A biopsy needle device constructed in a manner such that an internal needle is triggered in response to unlocking operation of internal needle locking device, after which a piston is retracted by a piston retraction spring in response to unlocking operation of piston locking device, whereby negative pressure is generated in a recess of the internal needle resulting in suction of biological tissue into the recess, and an external needle is triggered in response to unlocking operation of external needle locking device, thereby cutting and sampling the biological tissue which has been drawn into the recess.

Abstract: A method and system for performing a biopsy guided by a 3D image of the object obtained from digital tomosynthesis is performed. The method includes applying a compression paddle to an object; performing a tomosynthesis scan; reconstructing at least a portion of the scan; locating a lesion using a displayed or reprojected marker to determine a location of the lesion; correlating the location of the lesion in the scan to a marker on the compression paddle or tool holder; and proposing a needle entry point of a biopsy tool based off of the correlation so that a needle or penetration device will effectively reach the lesion or target if it is inserted at the proposed entry point. A system for performing a biopsy is further disclosed.

Abstract: A robotic surgery method includes tracking a position of a surgical tool as it is manually manipulated to perform a procedure. The tool is coupled to a handheld manipulator assembly, and the handheld manipulator assembly includes a handheld portion configured to be manually supported and moved by a user and a tool drive assembly supported by the handheld portion. The manipulator assembly further includes a plurality of elongate structural members coupled between the tool drive assembly and the handheld portion, at least one pivotal link arranged between the tool drive assembly and the plurality of elongate structural members, a plurality of lead screws and actuators supported by the handheld portion, and a controller in communication with the plurality of actuators. The method further includes selectively operating the actuators to move the tool drive assembly relative to the handheld portion based on the tracked position of the tool.

Abstract: In a medical manipulator, the surgical tool drive unit includes: a pair of input members that has a first input member and a second input member, are arranged in a pair at a first end portion in an attachment and detachment direction with respect to the surgical tool unit, are capable of advancing and retracting parallel to each other, and transmit the driving force in an advance direction when the pair of input members are advanced to the surgical tool unit side; and a drive source that causes at least one of the pair of input members to advance and retract.

Abstract: A biopsy device for percutaneous tissue removal includes an elongated housing having an operational axis, a stylet hub slidably mounted in the housing, where the stylet hub is movable relative to the housing between a proximal, armed position, and a distal, fired position, the stylet hub having a stylet strike, a cannula hub slidably mounted in the housing alongside the stylet hub, and a spring-biased arming member. The cannula hub is movable relative to the housing between a proximal, armed position, and a distal, fired position. The arming member is moveably mounted to the housing proximal of the respective stylet and cannula hubs, and configured for manually-actuated movement from a relaxed, extended position to a loaded, compressed position to define a compressive arming stroke. The biopsy device also includes an arming member biasing spring that restores the arming member from the compressed position to the extended position.

Abstract: A surgical instrument includes a housing, first, second, and third actuators operably coupled to the housing, an at least partially semi-rigid shaft extending distally from the housing, an end effector assembly disposed at a distal end of the shaft, and first, second, and third bars extending through the shaft in non-coaxial arrangement. The first bar is operably coupled between the first actuator and the end effector assembly such that actuation thereof effects manipulation of the end effector assembly. The second bar is operably coupled between the second actuator and a first deployable component such that actuation thereof effects deployment of the first deployable component relative to the end effector assembly. The third bar is operably coupled between the third actuator and a second deployable component such that actuation thereof effects deployment of the second deployable component relative to the end effector assembly.

Abstract: A biopsy device includes a cutter defining a cutter lumen and a tissue sample holder for collecting tissue samples. In one example, the tissue sample holder includes a rotatable manifold, and has a plurality of chambers that are each configured to separately hold tissue samples. A tissue sample holder rotation mechanism is operable to rotate the manifold to successively align each of the chambers with the cutter lumen. A controller in communication with the rotation mechanism is configured to rotate the manifold to a presentation position to present a collected tissue sample within a chamber to a user (e.g., at an angular position approximately 90 degrees from the cutter lumen). The controller is further configured to rotate the manifold align the next, empty chamber with the cutter lumen in response to a user input instructing the biopsy device to obtain another tissue sample.

Abstract: An ablation system including a first probe extending through a first longitudinal lumen from a proximal end to beyond a distal end of a flexible shaft, a first electrode coupled to a distal end of the first probe, and a first conductor electrically coupled to the first electrode. The ablation system further includes a second probe extending through a second longitudinal lumen from the proximal end to beyond the distal end of the flexible shaft, a second electrode coupled to a distal end of the second probe, and a second conductor electrically coupled to the second electrode. The first and second probes are rotatable and translatable within the first and second longitudinal lumens respectively. Furthermore, the first electrode and the second electrode are rotatably and translatably positionable with respect to one another, via the first probe and the second probe respectively, to define a region therebetween.

Abstract: A biopsy needle actuator includes an adjustable stop plate setting the distance a needle and cannula move when the actuator is fired, a shot counter tracking the number of shots taken with the actuator during a biopsy procedure, and a lifecycle indicator tracking the cumulative number of shots of the actuator during a recommended service life. A threaded rod sets the throw distance of the needle and cannula allowing the actuator to excise a biopsy tissue specimen of between 20 mm and 60 mm. A number wheel in the shot counter is moved upon firing of a needle carrier. The lifecycle indicator registers arming of the actuator and indicates when the mechanical components of the actuator need servicing. A biopsy needle within a cannula is mounted in the actuator where by the core bed of the needle is orientated downward when in use aiding in extraction of the tissue sample.

Abstract: A bone marrow access system includes a bone marrow access apparatus, a delivery tool that installs the apparatus in connection with a bone, instruments used while the apparatus is installed, and a removal tool to remove the apparatus. The apparatus includes a bone penetrating member having an internal channel having openings at proximal and distal ends, and a valve cap engaged with the bone penetrating member. The valve cap includes a valve having an opening having an open state in which the channel is not obstructed and a closed state preventing flow of material through the channel. The delivery tool includes a flange at one end and a drill bit extending beyond the flange. The flange fits in a seat in the bone penetrating member such that when the delivery tool is rotated while the flange is in the seat, the bone penetrating member is rotated into the bone.

Abstract: An intraosseous device includes a stylet with a pointed end for penetrating bone and a cannula through which the stylet extends. The stylet has a bent portion which is engaged in a receiver in a handle cover. The cannula has an outwardly extending flare which is engaged in a corresponding seat in a hub. The handle and the hub have formations which interlock with one another when the tip of the stylet is aligned with the tip of the cannula. The interlock formations further assist torque transmission. The configuration ensures that the maximum manual torque can be applied to penetrate bone while ensuring that the stylet and cannula are aligned for maximum cutting efficiency and remain fixed to the handle and the hub respectively.

Abstract: A surgical device includes a handle, an elongated tube extending distally from the handle, and a suction tip at a distal end portion of the elongated tube. The suction tip has a cavity formed therein. A cutting blade is positioned at least partially within the cavity and rotatable across the cavity to sever tissue, the cavity dimensioned to receive the severed tissue for removal from a patient's body.

Abstract: The present disclosure provides systems and methods for implanting an implantable cardiac monitor. An injection system includes an implantable cardiac monitor (ICM), a plunger, a plunger handle coupled the plunger, and an injector housing. The injector housing includes a tube extending from a first end of the injector housing to a second end of the injector housing, the tube configured to receive the ICM and the plunger, and at least one leaflet formed at the second end of the injector housing, the at least one leaflet configured to rotate outward when a user operates the plunger handle to push the ICM through the injector housing second end via the plunger.

Abstract: A method is provided for calibrating a surgical biopsy system. The biopsy system includes a biopsy instrument and control unit. The biopsy instrument includes a piercer, rotatable cutter, and a port for receiving tissue samples. The method comprises the steps of translating the cutter distally until the translation of the cutter is stopped at an extended position and recording the extended position. The cutter is then translated from the extended position proximally until the translation of the cutter is stopped at a retracted position proximal to the extended position. The retracted position is recorded. The method further comprises the step of rotating the cutter to a rotation speed while the cutter is located at the retracted position and, if determined that the rotation speed is within a predetermined rotation speed range, a feedback signal is provided on the display allowing the operator to progress to the next procedural step.

Abstract: The present disclosure relates to a terminal, and more particularly to a terminal and a method for providing health content. A method of providing health content using health information, includes receiving at least one piece of health information, comparing the received at least one piece of health information with a threshold value, and providing health content for a user to lessen a difference between the at least one piece of health information and the threshold value.

Abstract: An endoscopic endocap for excising a target portion of a native tissue from a remaining portion of the native tissue during a surgical procedure includes an annular main body. The main body has a proximal end and an oppositely disposed distal end. The distal end includes an extension that protrudes longitudinally beyond a remaining portion of the distal end. An outer surface of the distal end, and an inner surface of the main body, extend longitudinally between the proximal and distal ends. The inner surface defines at least one lumen with an opening terminating at the terminal portion of the distal end. At least one excisor is disposed on the extension with the excisor laterally spaced from the outer surface of the annular main body. The excisor remains stationary with respect to the lumen during use of the excisor to excize the target portion of the native tissue.

Abstract: A method and related system (IPS) to support definition of a sub-volume (SV) in an initial image volume (IV).

Abstract: A biopsy assembly including a biopsy catheter having a proximal portion and a distal portion, a navigation catheter configured to receive the biopsy catheter for positioning the biopsy catheter adjacent target tissue, wherein the biopsy catheter is configured to be received within the navigation catheter, a coring component, and an anchoring component configured to anchor the biopsy catheter to target tissue. The coring component includes a proximal region and a distal region, the distal region formed of one or more distally extending blades and the proximal region being coupled to the distal portion of the biopsy catheter and the one or more blades are configured to penetrate target tissue and sever a tissue sample from the target tissue.

Abstract: An arrangement for taking a biopsy in a human or animal tissue, comprising an elongated hollow member, comprising a proximal end and a distal end, wherein the elongated hollow member has a circular cross-section in a plane perpendicular to a longitudinal axis of said hollow member, and said distal end is provided with a cutting edge. The arrangement further comprising an elongated rod configured to fit inside said elongated hollow member, a longitudinal movement generating unit configured to generate an oscillating longitudinal movement of said elongated hollow member, or of an assembly of said elongated hollow member and said elongated rod via a connection assembly. The connection assembly is provided configured to assemble the elongated hollow member and the elongated rod by detachably fixating said elongated rod inside said elongated hollow member in a longitudinal position relative to said elongated hollow member.

Abstract: A needle assembly according to an exemplary aspect of the present disclosure includes, among other things, a cannula, a trocar insertable through the cannula, the trocar including a shaft extending longitudinally between a proximal portion and a tip portion and a groove formed in the shaft and extending from near the tip portion at least partially toward the proximal portion.

Abstract: A biopsy device includes a drive unit configured to receive a disposable unit having a needle carrier. The drive unit is configured to move a cutting element such that the needle carrier is driven a predetermined distance to move a needle-shooting mechanism to a cocked configuration. A user-actuatable control is configured to release the needle-shooting mechanism to cause the needle-shooting mechanism to shoot a biopsy needle simultaneously with the cutting element by an amount of the predetermined distance.

Abstract: A connecting element for a morcellator (M). The morcellator (M) has a hand module (1), a cutting tube (5) and a sleeve (8), the hand module (1) has a connecting piece (10) and the sleeve (8) has a connecting ring (9). The connecting ring (9) can be clipped onto the connecting piece (10).

Abstract: A living body heating instrument is pushed or inserted into an affected part to continuously perform cauterization and vaccinotherapy. A living body heating instrument that is pushed or inserted into an affected part of a living body to heat the affected part includes: an inner needle; and an outer needle having a hollow portion into which the inner needle is inserted through an opening at the needle base side toward the needle tip side. The inner needle has biocompatibility and thermal conductivity, and contains a heater. The affected part is cauterized by the heater with the inner needle inserted in the outer needle. Next, the inner needle is withdrawn, and a drug is injected through the outer needle, which remains inserted, to perform immunotherapy. A temperature detecting element may be provided in an inner part of the inner needle or on an outer surface of the outer needle.

Abstract: A biopsy needle consisting of a main portion, a linking portion and a front end portion wherein the main portion has a first bore of uniform circular cross-section, the front end portion has a smaller second bore of uniform circular cross-section and the linking portion has a shoulder between the first bore and the second bore. The outer surface of the linking portion is tapered. The open front end has multiple projecting teeth which serve to cut. There may also be serrations on the outer surface of both the front end portion and the linking portion. The biopsy needle has slits or holes to facilitate the expansion of the captured biopsy specimen and to inject cement for bone support. The needle assembly has a non-slip grip on multiple surfaces and pins hold components in place during rotation of the assembly.

Abstract: An implant resection system for preparing an implant site to replace a defect in an articular surface of a first bone includes a first guide configured to be coupled generally to the first bone. The first guide includes a body portion defining a channel configured to receive a pin, wherein the pin is configured to penetrate and form a longitudinally disposed bore within the first bone. The implant resection system further includes a second guide configured to be coupled generally perpendicular to the first bone proximate to the defect by way of the bore. The second guide includes a drill bit configured to form an excision site through a portion of the articular surface in preparation of receipt of an implant.

Abstract: A biopsy sampler comprising a penetration zone for receiving a part of an organism, a ram actuated to move along a path between a withdrawn position and an advanced position, a sample collector that cuts a biopsy sample from tissue in the penetration zone, and a container that receives the sample collector, the sample collector and the container being initially located on opposite sides of the penetration zone, a disposable shield initially located between the ram in the withdrawn position and the penetration zone, advance action of the ram to the advanced position bringing together the sample collector and container, and bringing the disposable shield into the penetration zone, withdrawal action of the ram to the withdrawn position withdrawing the disposable shield, leaving the tissue free to leave the penetration zone, such that in use in collecting a sample the shield contacts tissue surfaces and while the ram does not.

Abstract: Disclosed are embodiments of a removable tip device, which include a bone penetration feature at a distal end and a securing feature that allows the removable tip device to be removably secured to a distal end of various embodiments of a bone coring device. Some embodiments of the removable tip device include features that assist in transmitting torsional loads from the bone coring device to the bone removal feature. In addition, some embodiments of the removable tip device include a protective element that is configured to provide a protective surface for a distal feature of the bone coring device.

Abstract: A tissue anchor includes an elongated body having a proximal end and a distal end, and a barb mounted to the elongated body adjacent the proximal end for movement between a retracted position and an extended position in which the barb projects outwardly from the elongated body. An anchoring system includes an implantable device with a tissue contacting surface facing in a proximal direction, the tissue anchor having its distal end engageable with the implantable device and its proximal end adapted to project proximally beyond the tissue contacting surface to grip a living tissue, and a second resilient element that is mounted between the distal end of the anchor and the implantable device, the second resilient element being adapted to bias the anchor distally relative to the implantable device. Tooling and methods of insertion and removal are provided.

Abstract: A biopsy device for obtaining tissue samples from human or animal tissue is optimized for the sampling of tissues that are resilient and difficult to cut using conventional approaches. The biopsy device includes a cutting cannula, an inner member including a toothed rack having a sharpened distal tip configured to be introduced into the body and a sample notch for receiving the at least one severed tissue sample, the inner member receivable in the cutting cannula, and a cutting mechanism configured for causing the cutting cannula to be longitudinally displaced in a distal direction from a first position at the proximal end of the sample notch exposing the sample notch, to a second position at the distal end of the sample notch, so as to sever said tissue sample from remaining body tissue at the harvesting site. The toothed rack may be a rotatable and may be rigid.

Abstract: A device for collecting a tissue sample includes an outer needle extending longitudinally from a proximal end to a distal end and including a lumen extending therethrough. The device also includes an inner needle extending longitudinally from a proximal end to a distal end and including an opening extending laterally in and along a length thereof. The inner needle is sized and shaped to be slidably received within the lumen of the outer needle and movable relative thereto between an insertion configuration, in which the opening is covered by the outer needle, to a tissue collecting configuration, in which the opening is exposed. In addition, the device includes a handle assembly for adjusting a throw length of the inner needle relative to the outer needle.

Abstract: Exemplary embodiments of an apparatus can be provided for obtaining portions or samples of tissue from a target region of a biological tissue. One or more needles can be provided that have a small internal diameter, e.g., about 1 mm or less, and the needles can be configured to extract the tissue portions when the needles are inserted into and withdrawn from the tissue. Windows and/or markings can be provided on the wall of the needles to facilitate access to the sample. The needles can be provided in an enclosure, and an actuator can be provided to direct the needles into the tissue and/or withdraw them. A plurality of tissue portions having known relative locations in the target region can be obtained, and extraction of the tissue portions can be well-tolerated by the tissue as compared with conventional punch biopsies or the like.