Axially Spaced Balloons Patents (Class 604/101.05)
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Patent number: 8679058Abstract: An apparatus, a kit and a method for rapidly restoring blood flow through, and removing a clot from, a blood vessel by chemical dissolution. The essential components include an instrument for preventing the flow of debris downstream of the clot, a coronary catheter constructed to be introduced into the blood vessel and a double balloon catheter that has a tapered tip and that can form an enclosed space containing the clot and via which dissolution fluid can be brought into contact with the clot.Type: GrantFiled: April 25, 2012Date of Patent: March 25, 2014Inventor: T. Anthony Don Michael
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Patent number: 8652099Abstract: A medical device for the delivery of treatment fluid to body vessels is described. The device has a distal (21) and a proximal (20) end with a self-expanding, hollow tubular member (9) and a delivery catheter (10) suitable for deploying a self-expanding, tubular member (9). The tubular member (9) is configured to expand radially to form a central part (11) flanked by two annular ridges, which creates, in situ, an annular lumen that can apply treatment fluid locally to a vessel and a passageway that can maintain the flow of blood through the vessel. The device is particularly suited for minimally invasive and repeatable organ perfusion. A method for organ perfusion is also disclosed.Type: GrantFiled: March 20, 2007Date of Patent: February 18, 2014Assignee: Medical Device Works NV SAInventors: Joost J. Fierens, Eric Marcoux, Malika Omari
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Patent number: 8636724Abstract: This invention is generally related to catheters for insertion into a body cavity, duct or vessel, and more particularly to a tip or plug for a catheter. The catheter tip is constructed and arranged to form a seal on the end portion of the catheter tube, while a sleeve secured or formed integrally to the tip cooperates with the catheter tube to form a first balloon that encapsulates the tip of the catheter and a second balloon that positions the catheter within the body cavity, duct or vessel.Type: GrantFiled: October 26, 2010Date of Patent: January 28, 2014Assignee: Poiesis Medical, LLCInventors: Gregory D. Wiita, Bruce E. Wiita
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Patent number: 8636690Abstract: A catheter balloon with integral non-distending regions having a plurality of layers which wind around the balloon material and overlap to form an angle of between 45 and 90 degrees relative to each other upon inflation, and methods of making the non-distending regions are provided.Type: GrantFiled: November 2, 2009Date of Patent: January 28, 2014Assignee: W. L. Gore & Associates, Inc.Inventors: Alfred A. Alpini, Carey V. Campbell, Sherif Eskaros, David R. King, Joseph E. Korleski, Jr., James William Mann, Lonzo C. McLaughlin, Kenneth Newcomb, Peter J. Roeber
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Patent number: 8636722Abstract: Various forms of anti-clog suction tips apparatus are disclosed. For example, an anti-clog suction tip apparatus includes a suction tip assembly having a suction tip with a suction opening at a first end thereof for removing debris through suction, a hose attachment portion for attaching the suction tip assembly to a suction source, and an ejection wire channel. The apparatus further includes an ejection wire assembly having an ejection wire extending within the channel and an ejection button integral with or connected to the ejection wire. Applying a force to the ejection button advances the ejection wire through the channel such that an end portion of the ejection wire enters the suction tip and dislodges debris clogging the suction tip. The ejection wire may include an enlarged end portion such as, for example a ball tip. One or more of the components of the apparatus may be single-use and disposable.Type: GrantFiled: August 27, 2012Date of Patent: January 28, 2014Assignee: H & M Innovations, LLCInventors: Robert Sean Hensler, Thomas James Philpott, Daniel Lee Bizzell, Michael Starkey, Raeshon Lamont McNeil, Juan Carlos Perez, Thomas Eric Melin, Kenneth D. Ballard
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Patent number: 8617585Abstract: An intramedullary drug delivery device is disclosed and can be inserted within a bone canal of a bone. The intramedullary drug delivery device can include a housing. A drug delivery region can be established along the housing. Also, the drug delivery region can be configured to substantially span a fracture within the bone.Type: GrantFiled: March 23, 2006Date of Patent: December 31, 2013Assignee: Warsaw Orthopedic, Inc.Inventors: Scott D. Boden, Jeffrey L. Scifert, James S. Marotta
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Publication number: 20130345628Abstract: The present disclosure relates to a catheter having a longitudinal guidewire lumen defined by a first tube configured for an over-the-wire or rapid-exchange mode of operation, the wall of the first tube provided with an expansion member that is a sub-region of the wall of the first tube provided with an expandable material. An inflation lumen extending from the proximal end towards the distal end of the shaft is in fluidic contact with the expansion member, the member being configured to expand or contract responsive to pressure in the inflation lumen. The wall of the first tube may be formed from a helically coiled wire or helically braided wire having a helix angle of 60 degrees or more which tubing is resistive to radial pressure applied in the inflation lumen.Type: ApplicationFiled: February 16, 2012Publication date: December 26, 2013Applicant: ACROSTAK CORP BVI,TORTOLAInventors: Erwin Berger, Youri Popowski
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Patent number: 8603064Abstract: The present disclosure is directed to a catheter for site-specific delivery of a therapeutic agent to a blood vessel of a patient. The catheter further includes an elongated shaft having at least one inner lumen, a distal end and a proximal end and proximal and distal vessel-conforming balloons where each is separately positionable and inflatable, and when inflated, substantially restricts blood flow in the vessel and creates a treatment window of a defined but variable length for delivery of the therapeutic agent. The catheter optionally includes at least one marker band adjacent to the proximal balloon and at least one marker band adjacent to the distal balloon. At least one lateral aperture positioned in the window is in fluid communication with a drug delivery conduit located within either the inner shaft or the outer shaft to provide a homogeneous concentration of the therapeutic agent to the window.Type: GrantFiled: April 13, 2012Date of Patent: December 10, 2013Assignee: Covidien LPInventors: Neil Hattangadi, Daniel Lerner, Ryan Olivera
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Patent number: 8574222Abstract: An anti-clog suction tip apparatus includes a suction tip having a suction opening and an interior defining a suction channel. An ejection wire channel extends to a wire exit opening into the suction channel that is located proximate the suction opening. An ejection wire including a ball tip at an end thereof occupies the ejection wire channel and is transitionable between a retracted configuration and an advanced configuration such that, in the retracted configuration, the ejection wire including the ball tip is retained within the ejection wire channel and does not obstruct suctioning of debris through the suction channel; and in the advanced configuration, the ball tip of the ejection wire does not extend more than three millimeters beyond the suction opening.Type: GrantFiled: November 17, 2012Date of Patent: November 5, 2013Assignee: H & M Innovations, LLCInventors: Robert Sean Hensler, Thomas Eric Melin
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Publication number: 20130261544Abstract: A treatment device is disclosed for treating an area within a biological pathway or space. The treatment device includes a catheter that has a first pair of dilation balloons and a second pair of dilation balloons configured to create a sealed treatment area within a vessel. Treatment fluids may be provided to the treatment area via a fluid lumen and fluid may be removed from the treatment area via the same fluid lumen or separate aspiration lumen.Type: ApplicationFiled: March 27, 2013Publication date: October 3, 2013Inventor: Terry D. Hardin
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Publication number: 20130245607Abstract: Systems and methods are provided for performing a medical procedure within a patient's body that involves a thoracic duct including an ostium communicating with the patient's venous system. A distal end of a catheter is introduced through the patient's venous system into a body lumen adjacent the ostium of the thoracic duct. An expandable member on the distal end of the tubular may be expanded adjacent the ostium, e.g., within the body lumen or the thoracic duct itself, and used to isolate the thoracic duct from the body lumen, whereupon a medical procedure may be performed via the thoracic duct. For example, lymphatic fluid may be removed from the thoracic duct through a lumen of the tubular member and/or one or more agents may be introduced into the thoracic duct through the tubular member.Type: ApplicationFiled: May 3, 2013Publication date: September 19, 2013Inventors: Christian S. Eversull, Stephen A. Leeflang, Matthew J. Callaghan
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Patent number: 8535304Abstract: This invention provides a system and method that allows a therapeutic device, such as an atrial fibrillation microwave ablation catheter or ablation tip to be guided to a remote location within a body cavity and then accurately immobilized on the tissue, including that of a moving organ, such as the heart. In various embodiments, the system and method also enables accurate movement and steering along the tissue, while in engagement therewith. Such movement and engagement entails the use of vacuum or microneedle structures on at least two interconnected and articulated immobilizers that selectively engage to and release from the tissue to allow a crawling or traversing walking across the organ as the therapeutic catheter/tool tip applies treatment (AGE devices). In further embodiments that lack a movement capability (AID devices), the immobilizers allow a predetermined position for the introduced device to be maintained against the tissue while a treatment is applied to the location adjacent thereto.Type: GrantFiled: March 30, 2007Date of Patent: September 17, 2013Assignee: Ablacor Medical CorporationInventors: Martin J. Sklar, Howard Ring
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Patent number: 8529612Abstract: Materials and methods for producing localized hypothermia in a patient (e.g., for treatment of acute pancreatitis and pancreatic cancer).Type: GrantFiled: June 24, 2009Date of Patent: September 10, 2013Assignee: Mayo Foundation for Medical Education and ResearchInventor: Vijay P. Singh
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Patent number: 8454648Abstract: A prostate immobilizer has a shaft with a fluid passageway extending therethrough, a balloon affixed over an end of the shaft such that the fluid passageway communicates with an interior of the balloon, a lumen extending within the shaft so as to have an end opening adjacent an end of the balloon, and a device for locking a position of the shaft. The device has a positioning member having a stem portion extending from a head portion, and a locking member having a locked position and an unlocked position. The locking member cooperates with the stem portion of the positioning member so as to fix a position on the shaft. A channel is formed in the head portion so as to receive the shaft therein.Type: GrantFiled: March 25, 2009Date of Patent: June 4, 2013Assignee: RadiaDyne LLCInventor: John Isham
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Publication number: 20130096499Abstract: The present invention relates to a balloon catheter system for sealing puncture points or openings in body cavities, hollow organs or in percutaneous drainage operations in mammals, consisting of a filling catheter on the distal end of which a first balloon can be filled with the filling medium is arranged with a further balloon arranged proximally spaced apart therefrom. The balloons close the puncture point or the opening on the two sides in the filled state of the balloon. A hollow needle open at the shaft or the shaft end can be guided in the lumen of the filling catheter for filling the two balloons with the filling medium, wherein the shells of the two balloons enclose the shaft of the filling catheter. The filling catheter in each case has an opening arranged in the balloon lumen to fill the two balloons.Type: ApplicationFiled: April 20, 2011Publication date: April 18, 2013Applicant: UNIVERSITATSMEDIZIN DER JOHANNES GUTENBERG UNIVERSInventor: Michael Tchirikov
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Patent number: 8403876Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: March 7, 2012Date of Patent: March 26, 2013Assignees: Zoll Circulation, Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8398613Abstract: A surgical drain and method for using the same. The surgical drain comprises a first end, which may be sized for placement within an organism. The first end features a plurality of segments, each labeled with an alphanumeric character. The first end may be cut at a line between two of the segments. The alphanumeric character at the terminal end of the first end after cutting is recorded prior to placing the drain within the organism. When removing the drain, the recorded alphanumeric character is compared with the character at a terminal end of the first end of the surgical drain. Thus, a treating professional can ensure that no portion of the surgical drain is left within the wound, preventing infection due to a foreign object left within the organism.Type: GrantFiled: January 24, 2008Date of Patent: March 19, 2013Inventor: Michael R. Hahn
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Patent number: 8388586Abstract: An ostomy appliance is disclosed with an inflatable seal for sealing against the stoma. The inflatable seal has a first inflatable chamber portion for fitting inside the stoma to seal against the internal tissue. The inflatable seal also has a second inflatable chamber portion for sealing externally against the stoma and peristomal skin. In one embodiment, a tube extends through the inflatable seal to provide a communication passage for discharge of body waste without removing the inflatable seal. The tube floats with respect to an adhesive mounting member to allow a waist between the first and second inflatable chamber portions to self-locate in the stoma.Type: GrantFiled: February 21, 2008Date of Patent: March 5, 2013Assignee: ConvaTec Technologies, Inc.Inventor: Bret Weig
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Publication number: 20130053758Abstract: Disclosed are balloon catheters for forming liquid cast biodegradable arterial stents, typically, the balloon catheters include multiple balloons and multiple ports and include an element for promoting or initiating curing of a polymer solution via polymerization or cross-linking.Type: ApplicationFiled: October 15, 2012Publication date: February 28, 2013Applicant: NORTHWESTERN UNIVERSITYInventor: NORTHWESTERN UNIVERSITY
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Patent number: 8361016Abstract: The present subject matter describes a balloon catheter and methods of using the balloon catheter. The balloon catheter is particularly useful for pericardiocentesis and percutaneous pericardiotomy.Type: GrantFiled: July 23, 2010Date of Patent: January 29, 2013Assignee: Cedars-Sinai Medical CenterInventors: Robert James Siegel, David Singh, Bruce Addis, Huai Luo
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Publication number: 20130018308Abstract: A probe including a housing, a rectal muscle air bag, a rectal tube, an anal muscle air bag, and an anal tube is provided. The rectal muscle air bag mounts to the housing a first distance from a non-insertion end. A rectal tube is connected to the rectal muscle air bag at a first end and to a first pressure sensor at a second end. The anal muscle air bag is mounted to the housing a second distance from the non- insertion end. The anal tube is connected to the anal muscle air bag at a first end and to a second pressure sensor at a second end. The first distance is selected to position the rectal muscle air bag adjacent a rectal muscle, and the second distance is selected to position the anal muscle air bag adjacent an anal muscle when the housing is inserted in the rectum.Type: ApplicationFiled: July 12, 2012Publication date: January 17, 2013Inventors: Satish Sanku Chander Rao, Muralidhar Nukala Sunil Kumar
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Patent number: 8348891Abstract: To perform treatment by readily introducing a device causing minimal invasion even where approach from the body surface is difficult, a medical device includes a guide that is inserted into a lumen; a first balloon at a distal end of the guide, connected to a first flow path extending to a proximal end of the guide; a second balloon on the guide, separated from the first balloon on the proximal-end side and connected to a second flow path extending to the proximal end of the guide; a third balloon extending along the guide from a point between the first balloon and the second balloon to the proximal end and having a port for supplying or discharging fluid at the proximal end; and a cleansing flow path having a discharge port between the first balloon and the second balloon and extending to the proximal end of the guide.Type: GrantFiled: September 16, 2010Date of Patent: January 8, 2013Assignee: Olympus CorporationInventor: Michihiro Sugahara
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Patent number: 8323217Abstract: Methods to size a gastric pouch. In at least one embodiment for measuring the size of a gastric pouch of the present disclosure, the method comprises the steps of introducing a catheter into an esophagus, the catheter comprising an outer elongate tube, an inner elongate tube disposed within the outer elongate tube, a proximal balloon attached to the outer elongate tube, a distal balloon having a first end attached to the outer elongate tube and a second end attached to the inner elongate tube, at least two detection electrodes positioned on the outer elongate tube between at least two excitation electrodes, and a pressure transducer positioned on the outer elongate tube, locating the gastroesophageal junction using the proximal balloon, adjusting the distal balloon axially to a desired balloon length, injecting a fluid into the distal balloon to extend the distal balloon circumferentially, and determining a size variable of the gastric pouch.Type: GrantFiled: June 20, 2011Date of Patent: December 4, 2012Assignee: DTherapeutics, LLCInventor: Ghassan S. Kassab
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Publication number: 20120302953Abstract: An apparatus, a kit and a method for rapidly restoring blood flow through, and removing a clot from, a blood vessel by chemical dissolution. The essential components include an instrument for preventing the flow of debris downstream of the clot, a coronary catheter constructed to be introduced into the blood vessel and a double balloon catheter that has a tapered tip and that can form an enclosed space containing the clot and via which dissolution fluid can be brought into contact with the clot.Type: ApplicationFiled: April 25, 2012Publication date: November 29, 2012Inventor: T. Anthony DON MICHAEL
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Publication number: 20120296272Abstract: The invention relates to a catheter for transanal irrigation comprising a distal section (1) sufficiently rigid to be introduced into the rectum of a patient and provided with a rounded tip (3), a proximal section (2) intended to be connected to a source of irrigation liquid and a conduit channel (5) for irrigation liquid, opening out through at least one opening (6) close to the distal tip (3) of the distal section (1). The catheter is characterised in that the distal section (1) of the catheter is provided with an inflatable distal balloon (7) and an inflatable proximal balloon (8) intended to be positioned inside the rectum. The catheter is provided, moreover, on its distal section (1), close to the junction with the proximal section, with a mark that makes it easy to introduce the catheter and indicates to the patient the maximal extent of introduction of the catheter into the rectum.Type: ApplicationFiled: July 31, 2010Publication date: November 22, 2012Applicant: B. BRAUN MEDICAL SASInventors: Guy Bidault, Remi Collin
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Patent number: 8307830Abstract: A multi-layer inflatable balloon cuff may be adapted to seal a patient's trachea when associated with an endotracheal tube. The outer layer and the inner layer of the balloon cuff may have different material properties that may enhance a cuff's mechanical pressure seal by reducing wrinkles or folds that may form against a patient's tracheal walls.Type: GrantFiled: September 29, 2006Date of Patent: November 13, 2012Assignee: Nellcor Puritan Bennett LLCInventor: Jessica Clayton
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Patent number: 8292942Abstract: A system for delivery of a stent dilatable by means of a balloon, including a multilumen polymeric catheter having at least two balloons at the input end, where the distal balloon can expand an eccentric stent mounted on it, and the proximal balloon of smaller diameter has, at least, two radiopaque labels (markers) and has a capability of accurate orientation of the stent in an artery lumen.Type: GrantFiled: August 31, 2009Date of Patent: October 23, 2012Inventor: Alexander G. Viller
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Publication number: 20120259216Abstract: A balloon catheter with delivery probe and method of use for delivering a therapeutic agent and/or diagnostic agent to tissue is provided. The catheter has a balloon, a first lumen and a probe movably disposed in the first lumen of said catheter. The probe has a lumen for delivering a diagnostic and/or therapeutic agent to tissue. The catheter has a third lumen through which fluid is supplied to the balloon. The catheter with delivery probe may be inserted into a bodily cavity such that the distal end of the probe extends out of an opening in the catheter. When the balloon is inflated the probe is captured between an outer wall of the balloon and the tissue so that therapeutic and/or diagnostic agent may be delivered to the tissue through the probe lumen via the distal end of the probe.Type: ApplicationFiled: March 30, 2012Publication date: October 11, 2012Inventors: Lawrence J. Gerrans, Erhan H. Gunday
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Publication number: 20120259401Abstract: A method and apparatus for delivering a therapeutic and/or diagnostic agent to tissue within a bodily cavity is provided herein. The apparatus may include a catheter assembly including a catheter and a delivery balloon having an expandable material disposed thereon, wherein the expandable material may be an absorbent at least partially charged with a therapeutic and/or diagnostic agent. The method may include the step of delivering a therapeutic and/or diagnostic agent to tissue by inflating the delivery balloon by supplying fluid thereto until the expandable material adopts an expanded state in which the expandable material contacts the tissue and is implanted in a bodily cavity.Type: ApplicationFiled: March 30, 2012Publication date: October 11, 2012Inventors: Lawrence J. Gerrans, Erhan H. Gunday
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Publication number: 20120259215Abstract: An adjustable balloon catheter for extravasated drug delivery is disclosed generally including an outer catheter with a first balloon and an inner catheter with a second balloon. The inner catheter is moveably disposed in a lumen of the outer catheter such that the inner catheter moves relative to the outer catheter, changing the distance between the balloons. A fluid source supplies air to the catheters via lumens therein to inflate the balloons to create a chamber between them, and at least one of the catheters has a lumen for delivering a therapeutic and/or diagnostic agent to the chamber. The inner catheter is then moved relative to the outer catheter to decrease the size of the chamber between the balloons and decrease the fluid pressure therein such that the therapeutic and/or diagnostic agent is extravasated into the surrounding tissue.Type: ApplicationFiled: March 30, 2012Publication date: October 11, 2012Inventors: Lawrence J. Gerrans, Erhan H. Gunday
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Patent number: 8262605Abstract: Described are devices and methods related to the needleless injection of fluid into tissue of the lower urinary tract, such as the urethra and prostate.Type: GrantFiled: July 21, 2005Date of Patent: September 11, 2012Assignee: AMS Research CorporationInventors: Vincent G. Copa, Sidney F. Hauschild
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Patent number: 8251948Abstract: A catheter for delivering an agent to an area of treatment is presented. The catheter includes a catheter body, a balloon assembly coupled to the catheter body, a first lumen, and a second lumen. The balloon assembly has spaced-apart balloons that define an area between the balloons. The first lumen extends along the catheter body to pass an inflation material to the balloons to control an inflation level of the balloons. The second lumen extends along the catheter body and having an outlet in the area between the balloons. There may be a third lumen for bypassing a biological fluid such as blood while the catheter is being used. The method of using this catheter is also presented. The method entails simultaneously inflating the balloons to isolate a treatment area and adding an agent to the treatment area through one of the lumens.Type: GrantFiled: March 17, 2009Date of Patent: August 28, 2012Assignee: Vascular Designs, Inc.Inventor: Robert J. Goldman
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Patent number: 8241241Abstract: Clot disruption and dissolution are achieved using a catheter having the ability to infuse a thrombolytic agent, aspirate clot and fluid, and allow passage of a guidewire. Optionally, the catheter may also include a mechanical agitator for further disrupt clot in the presence of the thrombolytic agent. A flow resistor in the catheter provides for infusion and/or aspiration to be concentrated primarily at a clot treatment area in a blood vessel while also providing optional infusion and/or aspiration distal to the treatment area. In some embodiments, infusion, aspiration and guidewire passage occur through a common lumen. The thrombolytic agent, such as tPA, streptokinase, or urokinase, is directly released into the clot at the point where the agitator is engaging the clot. In this way, the thrombolytic activity of the agent is enhanced and the dissolution of the clot is improved.Type: GrantFiled: June 15, 2010Date of Patent: August 14, 2012Assignee: Tyco Healthcare Group LPInventors: Michael A. Evans, Denise Demarias, Dino De Cicco, Kelvin Ning, Alexander Khairkhahan, Tyler Jon Strang
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Patent number: 8224455Abstract: A method and apparatus of treating tissue adjacent a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema, includes injection of a drug-encapsulated within a heat-sensitive carrier, such as a liposome, within a region of tissue to be treated. The heat produced by the energy-emitting source heats a portion of the tissue surrounding the bodily conduit to a temperature of approximately 43° C. for a time sufficient to destroy the heated portion of the tissue. In addition, the heat produced by the energy-emitting source activates the heat-sensitive carrier to activate the release of the encapsulated drug and the drug targets the tissue to be heated. The focused energy of the energy-emitting source together with the compression acting on the target area can assist in delivering drugs to the target area so that a natural stent has a long term efficacy.Type: GrantFiled: October 12, 2010Date of Patent: July 17, 2012Assignee: Boston Scientific CorporationInventors: John Mon, Alan J. Fenn
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Patent number: 8206332Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: June 7, 2010Date of Patent: June 26, 2012Assignees: Zoll Circulation Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8187173Abstract: In a region where an intestine is movable in the abdominal cavity, conventional endoscope apparatus have suffered from a difficulty in moving an endoscope advancing portion toward a deep intestinal portion. An apparatus for advancing an endoscope is provided, which can be easily manipulated to advance medical instruments having endoscopic functions toward a deep portion. The apparatus includes first and second medical instruments, each having, at a distal end portion thereof, a balloon portion that can be fixed to an intestinal wall. In a fixed state, the balloon portion of the first medical instrument is configured to form a gap for enabling a distal end portion of the second medical instrument to advance therethrough. In a fixed state, the balloon portion of the second medical instrument is configured to form a gap for enabling a distal end portion of the first medical instrument to advance therethrough.Type: GrantFiled: July 16, 2008Date of Patent: May 29, 2012Assignee: Olympus Medical Systems Corp.Inventor: Hiroaki Miyoshi
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Patent number: 8182446Abstract: Catheter balloon assemblies (10) for delivering a therapeutic agent to a body vessel are provided, as well as related methods of manufacturing and methods of treatment. The catheter balloon assemblies may include a concentrically disposed dual balloon assembly at the distal portion of the catheter having an inner balloon (44), a porous outer balloon (42) concentrically arrayed around the inner balloon and a catheter shaft (30) adapted to deliver a therapeutic agent to the body vessel through the apertures in the outer balloon. Radial outward expansion of the inner balloon may urge the outer balloon into contact with the wall of a body vessel, where the therapeutic agent may be delivered from the catheter shaft through apertures in the outer balloon directly to the wall of the body vessel.Type: GrantFiled: September 11, 2008Date of Patent: May 22, 2012Assignee: Cook Medical TechnologiesInventors: Darin G. Schaeffer, David Christian Lentz
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Publication number: 20120101476Abstract: A catheter tip for an infusion catheter has a hollow tubular shaped base member with a pair of annular shaped inflation balloons positioned in parallel on the base member. A plurality of microfibers are mounted on the cylindrical surface section between the balloons. The microfibers are in fluid communication with the lumen of the catheter tip. In operation, the catheter tip is advanced into the vasculature of a patient and to a site in a small vein that is near the target tissue for infusion. The balloons are then inflated to anchor the catheter tip, and fluid medicament is infused through the microfibers. In an alternate embodiment, the microfibers can be replaced with at least one orifice.Type: ApplicationFiled: April 21, 2011Publication date: April 26, 2012Inventor: Guy P. Curtis
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Patent number: 8162879Abstract: The invention, in one embodiment, is directed to a catheter for site-specific delivery of a therapeutic agent to a blood vessel of a patient. The catheter further includes an elongated shaft having at least one inner lumen, a distal end and a proximal end and proximal and distal vessel-conforming balloons where each is separately positionable and inflatable, and when inflated, substantially restricts blood flow in the vessel and creates a treatment window of a defined but variable length for delivery of the therapeutic agent. The catheter optionally includes at least one marker band adjacent to the proximal balloon and at least one marker band adjacent to the distal balloon. At least one lateral aperture positioned in the window is in fluid communication with a drug delivery conduit located within either the inner shaft or the outer shaft to provide a homogeneous concentration of the therapeutic agent to the window.Type: GrantFiled: September 22, 2009Date of Patent: April 24, 2012Assignee: Tyco Healthcare Group LPInventors: Neil Hattangadi, Daniel Lerner, Ryan Olivera
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Patent number: 8109894Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: February 4, 2011Date of Patent: February 7, 2012Assignees: Zoll Circulation, Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8105263Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: February 3, 2011Date of Patent: January 31, 2012Assignees: Zoll Circulation, Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8105262Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: February 3, 2011Date of Patent: January 31, 2012Assignees: Zoll Circulation, Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8105264Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: February 4, 2011Date of Patent: January 31, 2012Assignees: Zoll Circulation, Inc., The Regents of the University of CalifoniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worchen, Yves Pierre Gobin
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Publication number: 20120020877Abstract: An intrauterine device and more specifically an intracervical device (ICD) for the local release of drugs in the loco-regional treatment of tumours of the uterine cervix comprises an elongated stem (2) to be positioned in the cervical canal (15), this stem consisting of an inner hollow core (3) and a coating (4) containing a gradual-release drug, the stem being attached to: a first element (5) for blocking the stem (2) inside the uterine cavity (12), and located at the cranial or upper end; a second blocking element (7, 71) positioned inside the vagina (11), against the ectocervix (16), located at the caudal or lower end of the stem (2).Type: ApplicationFiled: January 29, 2009Publication date: January 26, 2012Applicant: Fondazione IRCSSInventor: Francesco Raspagliesi
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Publication number: 20110295114Abstract: Devices and methods are described herein for engraftment of stem cells into a pancreas using an endovascular approach. Targeted intra-arterial injection of stem cells selectively in a splenic artery can achieve engraftment of insulin producing cells in the tail of the pancreas with high efficiency and without systemic circulation of these cells to other organs. In one embodiment, a catheter device includes expandable occlusion elements in the form of inflatable balloons that can be used to isolate a proximal and distal end of a pancreatic portion of the splenic artery. In another embodiment, the occlusion elements include a filter element instead of a balloon. In some embodiments, targeted delivery of stem cells to the pancreatic tail can be achieved for treatment of, for example, diabetes. In some embodiments, an arterial section of the splenic artery can be isolated for selective perfusion of therapeutic cells/drugs to the tail of the pancreas.Type: ApplicationFiled: December 2, 2010Publication date: December 1, 2011Applicant: RENOVORXInventors: Ramtin Agah, Kamran Najmabadi
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Patent number: 8016782Abstract: Methods are disclosed for the providing oxygenated blood to venous circulation. Embodiments include a femoral access approach to the creation of an Aorta-caval fistula at the bifurcation of the Aorta and the Inferior Vena Cava; an apparatus for the creation, modification and maintenance of a fistula; and a method of supplying oxygenated blood to the venous circulation of a patient. The devices, systems and methods can be used to treat patients with one or more numerous ailments including chronic obstructive pulmonary disease, congestive heart failure, hypertension, hypotension, respiratory failure, pulmonary arterial hypertension, lung fibrosis and adult respiratory distress syndrome.Type: GrantFiled: June 13, 2005Date of Patent: September 13, 2011Assignee: Rox Medical, Inc.Inventors: Rodney Brenneman, Douglas S. Cali, J. Christopher Flaherty
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Publication number: 20110218494Abstract: A method of extravasated delivery of a therapeutic and/or diagnostic agent to tissue is provided including inserting a catheter with a first balloon, a second balloon and a third balloon into a bodily cavity, inflating the first and second balloons by supplying fluid thereto to create a chamber, delivering the agent to the chamber, and increasing fluid pressure within the chamber by inflating the third balloon to facilitate extravasation of the agent into tissue. A multi-balloon catheter system is also provided including a catheter having a first balloon, a second balloon and a third balloon, and a fluid source that inflates the first and second balloons by supplying fluid thereto to create a chamber, wherein the catheter includes a fluid pathway for delivering the agent, and the fluid source increases fluid pressure within the chamber by supplying fluid to the third balloon such that the agent is extravasated into tissue.Type: ApplicationFiled: March 8, 2011Publication date: September 8, 2011Inventors: Lawrence J. Gerrans, Erhan H. Gunday
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Patent number: 7998113Abstract: A medical device including an element defining a central lumen and a secondary lumen. The device includes a prefilled balloon having an interior surface operatively communicates with the secondary lumen. The device includes a securement balloon having an interior surface communicating with the secondary lumen. The securement balloon, secondary lumen, and prefilled balloon define a closed fluid system. The securement balloon is stronger than the prefilled balloon so fluid in the closed fluid system inflates the prefilled balloon before inflating the securement balloon. The device includes a transfer sleeve movable from a first position spaced from the prefilled balloon to a second position positioned around the prefilled balloon to urge fluid from the prefilled balloon into the securement balloon. When the transfer sleeve is in the first position, the securement balloon is substantially collapsed. When the transfer sleeve is in the second position, the securement balloon is inflated.Type: GrantFiled: August 21, 2009Date of Patent: August 16, 2011Assignee: Tyco Healthcare Group LPInventor: David Rork Swisher
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Patent number: 7963929Abstract: Devices, methods, and systems for measuring the size of gastric pouches. At least some embodiments include a catheter comprising an outer elongate tube, an inner elongate tube disposed within the outer elongate tube, a proximal balloon attached to the outer elongate tube, a distal balloon having a first end attached to the outer elongate tube and a second end attached to the inner elongate tube, at least two detection electrodes positioned on the outer elongate tube relative to at least two excitation electrodes, and a pressure transducer positioned on the outer elongate tube.Type: GrantFiled: September 16, 2008Date of Patent: June 21, 2011Assignee: DTherapeutics, LLCInventor: Ghassan S. Kassab
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Publication number: 20110060276Abstract: Catheter balloon assemblies (10) for delivering a therapeutic agent to a body vessel are provided, as well as related methods of manufacturing and methods of treatment. The catheter balloon assemblies may include a concentrically disposed dual balloon assembly at the distal portion of the catheter having an inner balloon (44), a porous outer balloon (42) concentrically arrayed around the inner balloon and a catheter shaft (30) adapted to deliver a therapeutic agent to the body vessel through the apertures in the outer balloon. Radial outward expansion of the inner balloon may urge the outer balloon into contact with the wall of a body vessel, where the therapeutic agent may be delivered from the catheter shaft through apertures in the outer balloon directly to the wall of the body vessel.Type: ApplicationFiled: September 11, 2008Publication date: March 10, 2011Applicant: Cook IncoporatedInventors: Darin G. Schaeffer, David Christian Lentz