Abstract: A catheter flushing device includes a chamber covered with a movable member (e.g., a flexible diaphragm) that can be compressed by exertion of pressure on the diaphragm; and a valve having a first position allowing fluid from a fluid source to fill the chamber, and a second position allowing fluid from the chamber to flow through the catheter when pressure is exerted on the movable member. In particular, the catheter flushing device includes a housing having a cylindrical valve opening, an inlet port for connection with the fluid source, and an outlet port for connection with the catheter. The chamber is defined by a flexible diaphragm sealed about a region of the housing. The chamber can be compressed by manually exerting pressure on the diaphragm by means of a thumb or finger. A passageway extends through the housing from the chamber to the valve opening.

Abstract: Devices for injection of medicines into a human body are designed for one-time use during inpatient or outpatient treatment. The reuse of an injection device having a bellows 3 as an injection container is prevented by providing a locking attachment which prevents backward motion of a bottom 4 of the bellows 3 and which is mounted on elements of the device brought together during the injection (the bottom 4 of the bellows 3 and the housing/needle holder 1). A locking attachment is made in a form of a pair of interacting elastically deformable hooks 6 with a beveled catch and a female part in the form of a hole 7 with a ledge 8. At the instant the injection is completed, the sharpened end 10 of the needle 2 punctures a partition 9 in the bottom 4 of the bellows 3, further preventing reuse.

Abstract: A fluid supplying apparatus having a rubber elastic film (11) with fluid contained therein, an upstream tube (30), an intermediate station (40) disposed at a distal end of the upstream tube (30) and a downstream tube (27) connected to the intermediate station (40) is provided. The upstream tube (30) has two flow paths (31A and 32A) formed in a predetermined length extending in a longitudinal direction. The intermediate station (40) has a case (41), the case (41) having a fluid outlet (51) to which the downstream tube (27) is connected, a first communicating channel (52) for intercommunicating the fluid outlet (51) and one of the flow paths (31A), a reservoir (53) in communication with the other flow path (32A), a second communicating channel (55) having a check valve (54) at an intermediate portion thereof and intercommunicating the reservoir (53) and the fluid outlet (51), and a pressing member (56) for discharging the fluid stored in the reservoir (53) to the second communicating channel (55).

Abstract: A hypodermic injection system allows for the generation of a high pressure liquid jet capable of passing through the skin. The system uses two regions, the first region being flexible or squeezable and the second region having at least one exiting orifice through which the liquid jet can be expelled. The flexible region can be deformed by a pressure change in the surrounding container generated by an activatable gas generator that generates pressure within the first region that causes the liquid to be expelled.

Abstract: A liquid medicine self-administration device which is capable of administering a liquid medicine to a patient in a single shot and with which the refilling of the liquid medicine can be performed by a one-touch operation. The device includes a casing 1 having two open ends, a port portion 2 closing one of the open ends of the casing, a reservoir 3 attached to the port portion 2 and capable of being easily deformed by pressing and of being restored to its original shape. A pushing means 4 is slidably inserted into the other open end of the casing 1 and is adapted to press and deform the reservoir 3. The pushing means 4 comprises a cylindrical member 41 inserted into the casing 1 so as to be able to slide along the inner wall of the casing 1 and a spring 42 housed within the cylindrical member 41.

Abstract: A tissue sampling device, comprising a stylet having a notch therein and a cannula at least partially surrounding the stylet. The notch has an exposed portion for receiving tissue to be sampled, and the cannula is adjustable relative to the stylet to vary the size of the exposed portion and therefore the amount of tissue to be sampled. The device also comprises a trigger mechanism operatively connected to at least one of the cannula and the stylet. Actuation of the trigger mechanism causes relative movement of the stylet with respect to the cannula for collection of a tissue sample.

Abstract: A needleless dosage transfer system for filling medicating devices such as syringes or needleless cannulas to minimize the likelihood of an unwanted needle stick and to avoid the initial cost of a needle as well as the disposal cost of the needle. A vial has a body portion 20 formed with flexibly deformable walls and defines a blind bore. An opening of the vial includes a tapered section adapted to frictionally fit over a taper of a male luer-type fitting commonly found on syringes and needleless cannulas. By deforming the walls of the vial, fluid is forced from the vial into a syringe. The opening of the vial 10 is protected with a cap and includes a scoreline which, when fractured, defines the opening. The cap to be removed from the vial prior to its use is fabricated as one piece with the vial in order to assure sterile conditions during manufacture and filling. A tab is associated with the cap which lists the ingredients within the vial. The vial also supports an area which lists the vial's contents.

Abstract: A catheter assembly especially adapted for injecting therapeutic liquids such as DNA solutions to a patient's myocardium comprises an elongated guiding catheter for insertion through a patient's artery to the vicinity of the myocardium, a reservoir for therapeutic liquid at the distal end of the guiding catheter, one or more injection needles protruding from the distal end of the guiding catheter and in fluid communication with the reservoir, the extent of needle protrusion being appropriate for penetration of but not passage through the myocardial wall, and an operating device for delivering a predetermined quantity of therapeutic liquid from the reservoir through the needles.

Abstract: A thyrotomy punch set is provided including a housing having a bore formed along a central axis thereof. A punch includes a rod slidably situated within the bore of the housing with an outboard end and an inboard end. The outboard end of the punch is enlarged. Also included is a pair of springs for urging the outboard end of the punch outwardly of the housing such that the outboard end must be biased toward the housing.

Abstract: A device for delivering a liquid theraputic preparation into the body of a patient by injection into or through the skin of the patient comprises a low-profile housing having a bottom surface adapted to be brought into contact with the skin of the patient. A reservoir is disposed within the housing for containing a liquid theraputic preparation to be administered. An injection needle is disposed generally horizontally in the housing, and is adapted to communicate with the reservoir. The injection needle has a bent injection end which is adapted to project through a needle aperture in the bottom surface of the housing. A movable needle carrier is disposed in the housing for carrying the injection needle and for causing the injection end of the needle to project through the needle aperture upon movement of the needle carrier.

Abstract: A self-administration device includes a cylindrical casing opened at one end but closed at the opposite end. The closed opposite end is provided with a drug inflow port and a drug outflow port. An easily deformable and restorable reservoir is housed in the casing and is held by the closed end of the casing. The inflow port and outflow port are opened to the interior of the reservoir while a pushing device is provided at the open end of the casing and is movable along an inner wall of the casing to exert a pressure on the reservoir. A control device is provided for adjusting a moving distance of the pushing device to control a dosage of a liquid drug.

Abstract: An adjustable surgical clamp having an axis that is adapted to releasably engage the outer surface of a cylindrical instrument such as a trocar. An elastomeric sleeve has an outer surface and an inner surface which is sized to frictionally engage the instrument. A constriction member forming a ring around the sleeve is operable between a first position wherein the ring has a first diameter and a second position wherein the ring has a second diameter. A pair of tabs attached to the constriction member are movable relative to each other to operate the constriction member between the first and second positions. A tube extending axially of the constriction member includes a protrusion which may be in the form of a helix, a plurality of annuli or an inflatable balloon enhances the fixed relationship with a body wall.

Abstract: A gas-tight seal module is incorporated in a trocar system to form a gas-tight seal about an instrument inserted into the cannula of the trocar system. The module incorporates an apertured disc. The aperture in the disc can be stretched to accommodate a seal about an instrument inserted into the cannula. The disc is carried by a flaccid membrane which extends across the module. A pair of rigid washers clamped on opposite sides of the disc are constrained for movement between two parallel spaced surfaces. The disc is thus freely moveable in its own plane to accommodate off-axis movement of the instrument thus avoiding the breakage of the seal with the instrument which would otherwise occur if the disc did not have the same freedom of movement. The disc also acts to clean the surface of the instrument when withdrawn so as to avoid contamination of a flap valve upstream of the disc.

Abstract: A portable analgesic system comprises: a continuous injector (1) for liquid medicine which discharges liquid medicine continuously for a given period of time; a switch valve (2) connected to an outlet of the injector for shutting off discharge of liquid medicine from the injector (1); a three-way connector (3) to an outlet of the switch valve (2) and having three ways; a flexible reservoir (4) connected to one way of the three-way connector for storing liquid medicine; and a pressure-check valve (5) connected to another way of the three-way connector for opening a flow passage only when a pressure of liquid medicine in the reservoir rises over a given value.

Abstract: This invention relates to a portable medicant injection device having a diaphragm mounted within its housing and a hypodermic needle that moves in response to the movement of the diaphragm when pressurized gas is released into the housing.

Abstract: A safety penetrating instrument for introducing a portal sleeve into an anatomical cavity particularly useful in least invasive surgery includes a safety probe having a distal end configuration cooperating with the sharp distal tip of a penetrating member to protect the tip in an extended position and to expose the tip in a retracted position. The configuration of the distal ends of the penetrating member and the safety probe in the retracted position form a solid, continuous surface tissue penetrating tip for the safety penetrating instrument. The safety probe and penetrating member can be removed from the portal sleeve as a unit or the safety probe can be removed while leaving the penetrating member in place for use in further procedures. The safety probe can carry interchangeable protective bodies on the distal end thereof, the bodies being made of flexible, pliable and preferably resilient materials.

Abstract: An IV infusion method and apparatus includes a plurality of fluid pumps mounted within a portable support housing and coupled to an IV tube. Each separate fluid pump is adapted to deliver fluid at a substantially constant delivery pressure predetermined by the characteristics of the pump. Each fluid pump includes an elastomeric membrane stretched into its region of nonlinear elasticity over a contour surface. Check valves located between the pumps and the IV tube control sequential dispensing of fluids from the pumps. The method and apparatus are especially adapted to a SASH process.

Abstract: Apparatus for regulating pressure in and for controllably pressurizing infusion devices includes a flow-through pressure gauge for indicating and regulating the pressures within such infusion devices between minimum and maximum desirable pressures. Such apparatus includes a gauge, coupled between a fluid source and the bladder portion of the pressure infusion device. The gauge receives pressurized fluid from the fluid source, provides fluid to the bladder, indicates a range of fluid pressures in the bladder and maintains the pressure of fluid in the bladder between minimum and maximum pressures. The gauge includes a telescopingly coupled member to indicate a range of pressures in the bladder. A first valve permits the passage of fluid through the gauge and into the bladder when the fluid pressure exceeds a minimum pressure. A second valve prevents the passage of fluid through the gauge and into the bladder when the fluid pressure exceeds a maximum pressure.

Abstract: An intradermal injection device, comprised of a fine gauge injection needle and hub, is enveloped by an attached flexible tear-drop shaped bulb containing a reservoir, and which is itself attached to an integral sliding needle guard. The device contains a prepackaged dose of medication to be administered, which is sealed into the hub and bulb reservoir. Using the hub as a convenient handle, the needle is injected into the skin and the medication is discharged by squeezing the bulb between the thumb and forefinger; afterward the sliding needle guard is deployed by the same squeezing action. A hypodermic injection device, longer needle variation, is accomplished by a modification in the form of an extension to the bulb of a sleeve folding or invaginating over itself, allowing the integral sliding needle guard, when deployed, to extend over the longer needle.

Abstract: An apparatus for the patient-controlled delivery of a beneficial agent comprising a dose reservoir for receiving and storing a beneficial agent, inlet means to and outlet means from the dose reservoir and pump means operative in response to an external force supplied to the pump means for drawing beneficial agent into the dose reservoir at a relatively constant rate and for discharging the beneficial agent out of the dose reservoir through the outlet means.

Abstract: A liquid container comprises a container body (2) having an opening (12) and a liquid-containing portion (2a), the container body containing liquid (W) therein; a cap (3) integrally formed with or fixedly connected to the opening after the liquid is charged in the container body, the cap having a base portion (3a) continuous to the opening, a thin-wall portion (3b) continuous to the base portion, a top portion (3c) continuous to the thin-wall portion, and at least one horn plate portion (13) continuous to the top portion, the horn portion radially outwardly extending beyond the diameter of the top portion; a cap opener (5) provided around the cap to be rotatable with respect to the cap, the cap opener having at least one craw plate (15) radially inwardly extending from inner wall of the cap opener to be in contact with the horn plate when the cap opener is rotated, an opening (5d) being made in the cap opener so as to exhaust the liquid (W) therethrough after the thin-wall portion is cut by twisting the cap o

Abstract: A subcutaneously implantable medication infusion device includes a variable capacity reservoir for receiving and storing fluid medication for delivery to a catheter which directs the medication to a specific infusion location in the body. A control assembly is interposed between the reservoir and the catheter to facilitate and control the transfer of the medication from the reservoir to the catheter in a safe and efficient manner. The control assembly includes a self-recharging pump and a normally closed valve, both of which are manually actuable by percutaneous pressure when subcutaneously implanted, and a one-way valve positioned within a primary fluid conduit between the pump and the normally closed valve. The control assembly is constructed to permit the infusion of a measured bolus of medication on demand through manual percutaneous manipulation of the control assembly.

Abstract: A catheter assembly of the hypodermic embedment type for infusing a fluid medicament such as a carcinostatic agent into a body cavity such as a blood vessel for therapeutic purposes, includes a medicament infusion implement having an inlet port and an outlet port and a catheter connected to the implement outlet port. The device is used by inserting and indwelling the catheter in a body cavity and embedding the implement beneath the skin. Treatment can be repeated any number of desired times with the catheter assembly kept indwelled in the body, resulting in a significant reduction of the burden to the patient as compared with the prior art technique requiring insertion and withdrawal of a catheter every time when treatment is made. Also, the danger of infection during the treatment is eliminated, as compared to the prior art technique where the catheter is percutaneously inserted.

Abstract: An apparatus (60) and system (20) are disclosed for the patient-controlled delivery of an analgesic or other beneficial agent 142, while preventing administration of a toxic quantity of the beneficial agent. The invention permits delivery of fractional doses to a patient in quantities which are directly proportional to the time period since the last dose or fraction thereof was delivered to the patient. In the preferred embodiments the apparatus includes a housing (58) including a casing (88) and a back plate (86), the housing containing a control switch (84) for opening and closing downstream conduit (62) and for depressing a floating plate (100) that thereby compresses a dose reservoir (90) with the beneficial agent (142) therein. A spring (124) biases the control switch (84).

Abstract: A compensating valve and a drainage system for draining a body fluid from one body region to another body region. The system enables routine drainage at predetermined differential pressures, provides for pumping action, for flushing action to clear the system of obstructive material, and for resisting over-drainage which can occur when the patient makes an abrupt and relatively large change in his position. A compensating valve purpose has a valving action which is proportional to various parameters so as to enable continuous and proportional control for drainage rather than an on/off control.

Abstract: A surgically implantable shunt system, including a flow control valve and an antechamber, is provided for controlling the release of entrapped body fluids. The flow control valve includes a pair of molded plastic bases situated, respectively, adjacent to an inlet and an outlet of the valve, which bases are situated within a flexible encasement. Each base includes an outer housing, a valve membrane carrier positioned within the housing, and a flow control member. The flow control members each include a rigid nail-like central support and a separate flexible resilient membrane positioned on the central support. A first flow control member is capable of selectively occluding the valve inlet, but is normally spaced from its base to permit free fluid flow through the inlet. The second flow control member is generally arch-shaped and resiliently biased to contact its respective base generally along the outer edge of the membrane in a manner permitting only controlled one-way flow through the valve.

Abstract: The implantable device for the repeated injection of medicament (20) in unitary does in at a frequency which is a function of the therapeutical treatment needs comprises essentially: a flexible reservoir (6) for the storage of the medicament. A first flexible connection tube (7) connecting the reservoir to an injection site (5) a small flexible balloon for the predosing and controlling of the injection of the medicament, a second flexible connection tube (9) connecting the small balloon (10) and the reservoir (6), a valve fitted with valve means (16) of the type responsive only to the pressure exerted to small balloon means (11) for controlling the flow rate for filling the small balloon (10), and provided on said second connection tube (9), a non-return valve (21) provided immediately upstream of the control balloon (10). Application to therapeutic treatments.

Abstract: A modular infusion pump system utilizes a positive displacement pump for pumping a known quantity of fluid for each stroke. A plurality of longitudinally spaced apart fixed combs cooperate with a resilient tube to define a known pumping volume. A plurality of movable combs are interdigitated with the fixed combs and are periodically linearly directed to cause the pump volume to be compressed, and therefore the fluid expelled. A rotary to linear drive system is connected with the movable combs and a ratchet system prevents counterrotation when the motor is in the off position. Valves are disposed above and below the pumping unit to appropriately seal off the pumping volume. The valves and the movable combs are operated by means of cams carried by a common shaft.

Abstract: An implantable pump, actuated by the patient in whom the pump is implanted, to provide pain relief and/or other therapeutic benefits. There is disclosed a fully implantable pump system, including a reservoir for holding fluid, a septum by which the reservoir is periodically refilled, and a resilient pump chamber responsive to manual pressure, for delivering limited amounts of the fluid through a catheter to a specific location within the body of the patient. Alternative embodiments disclosed include designs incorporating "windkessel-like" devices for controlling discharge of the fluid to the specific location to occur over extended time periods at relatively constant flow rates.

Abstract: A medical pump comprising an intake/discharge nozzle, a fluid circulator, an elongate barrel extending between and joining the nozzle and circulator, a flushing path and an efflux path peripherally about the flushing path connecting the circulator and nozzle, non-return valves within the paths providing for uni-directional flow from the nozzle through the efflux path to the circulator and from the circulator through the flushing path to the nozzle. A debris-collecting filter element is disposed within the efflux path within the barrel. The filter element and valves may be in the form of a replaceable cartridge. The valves may be constructed as a shuttle with joined oppositely operating valve plates. The valves may also comprise a resilient flap member with a flap formed therein, both the flap member and flap being independently operable and defining the two valves.

Abstract: A support for a biomedical implant device in which the support has a surface layer composed of a biocompatible calcium phosphate material such as sintered hydroxyapatite with a porosity of 50-60% and pore size of 0.5-500 micrometers. Preferably, the surface layer is formed with projections or recesses of a few hundred micrometers size.

Abstract: A fluid flow control device for controlling the flow of fluid from one region of the body to be drained to another region. The device includes a rigid cartridge combined with an elastomeric valve element. The design of the cartridge and valve element are such that the cartridge incorporates a seat and when the valve element is properly positioned within the valve body by a novel positioning arrangement it has sufficient spring force to push against the seat, thus creating a seal. The valve element ensures uni-directional flow as well as creating a set resistance to that flow. The unit can be easily assembled without the use of adhesives and in one configuration, the valve can be "tuned" to a desired pressure as a final assembly step. Combining two of the basic valving assemblies in series with an elastomeric section therebetween results in a valve system which can actively pump fluid downstream by squeezing the central connecting section.

Abstract: A subcutaneous access site to aid in the delivery of chemotherapeutic or analgesic drugs to the blood stream or to any body cavity. The device embodies a specially supported septum which exhibits exceptional resealing characteristics. In this regard, the device includes a rigid inner ring adapted to create uniform circumferential compression on the septum member to enhance site resealing even when standard twelve degree beveled hypodermic syringe needles are used. Additionally, the device is uniquely configured to give immediate feedback to the caregiver if the needle misses the target, thereby minimizing accidental subcutaneous injections.

Abstract: The invention concerns a sequential and manually actuated feed device for implantation in an accessible subcutaneous region of a patient for the purpose of sequentially dosing a liquid, in particular a therapeutant. This device comprises a reservoir consisting of a flexible pouch, a filling site (2) located at the rim of said pouch in order to inject the liquid into it, and a manual pump (3) located in the opposite zone of the pouch in order to supply the liquid dose by dose to a catheter (20). The pump has a rigid case with a recess and bearing an expulsion membrane so as to bound a volume chamber; safety means prevent any accidental injection in the event of a spurious pressure exerted on the flexible pouch.

Abstract: An injection system and method for delivering fluids to a subcutaneous body site such as an analgesic to the ventricle is disclosed. A reservoir containing a plurality of doses of the fluid is adapted to be subcutaneously located in the abdomen. This reservoir is connected by a catheter to a subcutaneous unit containing a valve and a pump. This unit is then connected to the ventricle of the user. By the simultaneous actuation of the valve and the pump, the analgesic is pumped to the ventricle of the user. Preferably, the reservoir includes an expandable bag and a bubble member on the outermost surface of the bag which is penetrable by a small needle on the outersurface and impenetrable on the innersurface. A fluid passageway then connects the bag and the bubble member so that the bag is easily refilled. The pump and valve are preferably operated by flexible portions on the subcutaneous unit, which flexible portions are preferably recessed to prevent inadvertent actuation.

Abstract: This invention relates to a "plungerless" means of drawing blood and for administering liquids via parenteral injection. This means is used in conjunction with a pouch bearing an injection means, to which it is releasably attached. It comprises hinged plates which, when folded, expand the pouch; and which, when straightened, compress it.In a preferred embodiment, the plates fold along a line essentially parallel to the general direction of fluid flow, and extend beyond the distal end of the pouch. The expanded pouch may then be rested on the distal edges of the plates, which form a "diamond" configuration.

Abstract: An implantable demand medication delivery assembly for delivering measured aliquots of liquid medication. The assembly includes a reservoir which stores the liquid medication to be delivered. The assembly also includes a pump which is in fluid communication with the reservoir. The pump includes a housing having an inlet port in fluid communication with the reservoir and an outlet port. Connected to the outlet port is a delivery catheter for delivering the liquid medication to a site within the patient wherein the assembly is implanted. The pump also includes a fluid passage which extends between the inlet and outlet port. A chamber is provided along the fluid passage for containing a preselected volume of liquid medication to be delivered. A resilient deformable wall on the pump extends over the chamber. A one-way valve is provided in the fluid passage between the inlet port and chamber for permitting fluid flow toward the chamber.

Abstract: A valve assembly for relieving intracraneal pressure includes a valve housing adapted for implantation and having an inlet port for connection to a ventricular catheter and an outlet port for connection to a venus or peritoneal catheter. The valve housing includes a fluid passage, the flow through which is controlled by a first pressure responsive valve of relatively high resistence and a second pressure responsive valve of relatively low resistence spaced downstream of said first pressure responsive valve. An attitude responsive valve is disposed in said fluid passage in parallel with said first pressure responsive valve. The valve assembly is implanted in a patient with the attitude responsive valve in a closed position when the patient is in an upright position and in an open position when the patient is in a horizontal position. The employment of pressure responsive and attitude responsive valves in parallel provides ventricular pressure relief regardless of the patient's position.

Abstract: A periodontal pocket irrigating and treatment system includes a dispenser capable of containing a medication. The system enables an individual patient to self-administer a medication or irrigant into periodontal pockets while at home or travelling. A housing holds a tube of medication, and a roller squeezes the tube, thereby releasing an incremental portion of the medication therefrom. A control, operable from the outside of the housing, urges the roller in increments along the interior of the housing, squeezing the tube in a controlled fashion. A nozzle is attached to the tube for delivering the medication from the tube through a nozzle outlet end of small diameter to the periodontal pocket. Optionally, a flexible tip is attached to end of nozzle for elimination of pain and for guidance around curvatures of the periodontal pocket. A ratchet preferably controls the amount of medication dispensed by the device.

Abstract: The present invention is directed to subcutaneous peritoneal injection catheters and methods which minimize catheter obstruction during use. The apparatus includes a receiving chamber or reservoir having a relatively small internal volume while employing a penetrable membrane and relatively enlarged target surface area. The reservoir is interconnected with the peritoneal cavity by a hollow stem. The penetrable membrane accommodates a hollow needle being inserted into the receiving reservoir and is configurated with a dome-like profile so that the membrane may also be depressed to expel insulin from the receiving reservoir into the peritoneal cavity in a direction generally toward the mesenteric peritoneal membrane.The distal end of the hollow stem (which is situated inside the peritoneal cavity), is constructed so as to minimize the likelihood of catheter obstruction during use by a patient.

Abstract: The present invention relates to an inlet blood filter assembly. The inlet blood filter assembly includes a drip chamber, filter chamber and pump chamber. The assembly is constructed so that blood flows through the drip chamber, into the filter chamber and into the pump chamber. The inlet blood filter assembly is blow molded so that the thickness of the walls of the chambers may be varied.

Abstract: An implantable metered dose drug delivery system is disclosed which comprises implantable components including an injection site, reservoir, metering valve and delivery catheter, all of which are interconnected through suitable tubing. The metering valve has a domed body constructed of a resilient elastomeric material with a fluid-flow passageway extending therethrough and opening into a chamber within the domed body. A valve is positioned within an outlet leading from the chamber, which valve is opened by exerting an external pressure on the domed body to first collapse and occlude the fluid-flow passageway and then open the valve to permit medication within the chamber to flow through the outlet. Upon release of the external pressure, the fluid-flow passageway opens and reduced pressure in the chamber draws additional fluid through the passageway to fill the chamber.

Abstract: A manually operable resuscitator bag of one-piece construction having a generally elongated football shape, an inlet at one said end, and an outlet at the other end, fold-rings in each end portion having walls of reduced thickness, whereby the ends may be telescoped, ridges of thickened wall section between the fold-rings, the center of the bag having a wall thickness equal to the thickness of said ridges in the tapering ends between the fold-rings, and longitudinal ribs formed on the outer surface of the center of the bag spaced around the circumference, providing increased resiliency and a rapid recovery for the shape of the bag.

Abstract: A multiple fluid pulse dispenser comprising a plurality of interconnected fluid reservoirs defined by mating, oppositely directed concavities at least one of which mating concavity is formed from an invertable, preferrably permanently deformable blister. The reservoirs are in fluid communication with an outlet through which the contents of the reservoirs may be dispensed. A preferred embodiment permits fluid to flow through a reservoir after it has been discharged to allow random activation of the individual reservoirs.