Abstract: The present invention relates to a monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device, wherein the monitoring device comprises: a fastening member (32) to releasably attach the monitoring device to an axially elongated housing (14) of the drug delivery device (10), a sliding member (40) shiftable relative to the fastening member (32) in an axial direction (1, 2) and being adapted to operably engage with at least one dose setting component (17, 18, 26) of the drug delivery device (10) to follow an axial displacement of the dose setting component (17, 18, 26) relative to the housing component (14), a first sensor arrangement (36, 46) for detecting a rotation of the dose setting component (17, 18, 26) relative to the fastening member (32), a second sensor arrangement (38, 48) for detecting an axial displacement of the sliding member (40) relative to the fastening member (32), and a processing member (34) coupled to the first and to the second sensor a

Abstract: A pen type drug injection device includes a housing, a dose dial member, a torsion spring fixed between the housing and the dial member such that energy is accumulated in the torsion spring upon rotation of the dial member relative to the housing, a drive member engaging a lead screw, a first clutch, and a second clutch. The first clutch couples the drive member and the housing, in a coupled state and allows relative rotation between them in a de-coupled state. The second clutch rotationally couples the drive member and the dial member in a coupled state and allows clockwise and anti-clockwise rotation between them in a de-coupled state. The second clutch includes a ratchet clicker with teeth having different tooth angles in the clockwise and the anti-clockwise direction, such that, in the de-coupled state, the teeth override each other with different resistance in opposite directions.

Abstract: An image processing apparatus includes a three-dimensional space information storage unit, a projection unit, an operation acquisition unit, a reference guide rail decision unit, and a motion vector calculation unit. The projection unit projects and draws a cross-sectional plane onto a projection plane on the basis of information on a position of the cross-sectional plane stored by the three-dimensional space information storage unit. The reference guide rail decision unit decides a reference guide rail on the basis of information on a position of a slide operation acquired by the operation acquisition unit.

Abstract: The present invention is directed to a drug delivery device comprising a cartridge with a movable bung, a drive mechanism including a bearing for driving the bung in a distal direction for delivering a medicament and a piston rod for actuating the bearing. An electric conductor for transmitting an electrical signal is provided, wherein the electric conductor is configured such that a conductive connection is established or interrupted when the piston rod contacts the bearing or when the bearing contacts the bung. The invention is further directed to a method for detecting the contact between the drive mechanism and the movable bung.

Abstract: An injection device (1) for administering a fixed dose of a medication is provided. The injection device (1) comprises a housing (2) wherein a drive mechanism comprising a drive member (3) is at least partially enclosed and a dosing element (34) which is fixed relative to the drive member (3). Here, a dose can be set by rotating the dosing element (34) relative to the housing (2) in a dose set direction (105) and the dose can be dispensed by pushing the dosing element (34) towards the housing (2). Moreover, a method is provided for operating an injection device (1) for the administration of a fixed dose of a medication: A dose can be set by rotating a dosing element (34), a dose can be dispensed by pushing the dosing element (34) towards the housing (2) and a dose can be cancelled by rotating the dosing element (34) in a direction (106) opposite to the dose set direction (105).

Abstract: An optical decoding system including an optical sensor integral with or attachable to a housing of a drug delivery device and configured to be directed at first and second rotatable components of a dose setting and dispensing mechanism of the drug delivery device and a processor configured to: (i) cause the optical sensor to capture images of the first and second rotatable components at least at the beginning and end of a medicament dose dispensing process; (ii) determine a rotational position of both the first and second rotatable components in each of the captured images; and (iii) determine from the rotational positions of the first and second rotatable components an amount of medicament delivered by the dose setting and dispensing mechanism of the drug delivery device.

Abstract: A medial assembly comprises a logging first unit adapted to be mounted on a drug delivery device second unit from a fully un-mounted to a fully mounted position along a path. The first unit comprises a switch operatable between an off- and an on-state when the first unit is mounted on the second unit, the switch being in the on-state when the first unit is mounted within a first distance from the fully mounted position, and in the off-state when the first unit is mounted outside the first distance from the fully mounted position, and a snap lock operatable from an initial state through an expanded state to a snap-in state when the first unit is mounted on the second unit, the snap lock being in the snap-in state when the first unit is mounted within a second distance from the fully mounted position, the second distance being shorter than the first distance. By this arrangement it is ensured that the switch will be in the on-state before the snap lock is in the snap-in state.

Abstract: A set of members for a drug delivery device comprises at least two components for the device, wherein both components are provided with a marking, the markings being substantially equivalent or identical. Furthermore, a drug delivery device and a set of drug delivery devices are provided.

Abstract: The invention relates to a torsion spring driven injection device having a dial-down mechanism for dialling down a selected dose size. The torsion spring (2) is strained when setting a dose by rotating a proximally located dose setting button(30) relatively to the housing in a first direction and unstained when rotating the same dose setting button (30) in a second direction opposite the first direction. In order to secure the torsion spring (2) in its strained position a one-way ratchet mechanism is provided. This one-way ratchet mechanism comprises a fixation element (1) coupled to the housing and having a toothing (6) and a ratchet element (20) having at least one ratchet arm (22) engaging the fixation element (1) and which ratchet element (20) is operational coupled to the dose setting button (30).

Abstract: Embodiments described herein generally relate to devices, systems and methods for measuring a volume or number of doses remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a light guide disposed and configured to reflect electromagnetic radiation toward the container. The dose measurement system also includes a light guide disposed and configured to emit electromagnetic radiation into the light guide. A plurality of sensors are located in the apparatus that are optically coupleable to the light guide and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light guide. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors.

Abstract: A drug delivery device for setting and dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal axial direction. The drug delivery device further includes a drive spindle operably engageable with the piston rod during dose dispensing and a drive member axially displaceable relative to the drive spindle against the action of a spring element during dose setting and being threadedly engaged with the drive spindle to form a spindle gear.

Abstract: A injection site information cap includes a housing, a cover portion, an engagement portion configured to couple to and cover an injection port of an injection site, and at least one information element on the cover portion that is positioned to be automatically sensed by at least one sensor of the injection site when the engagement portion is coupled to or is being coupled to the medication injection port. Related apparatus, systems, and techniques are also described.

Abstract: Embodiments of the invention provide systems and methods for delivering therapeutic compositions to the inner-ear to treat inner-ear disorders. An embodiment of such a system comprises a sheath for insertion into the auditory canal and a cannula which can be inserted through the sheath. The cannula can include a tip for piercing the tympanic membrane and delivering the composition to an inner-ear tissue surface. The system may also include a therapeutic composition comprising a therapeutic agent and a thixotropic material which allows the composition to be delivered (e.g., by injection) through the cannula in liquid form and transition to gel-form once delivered to the tissue surface. A method for using the system comprises introducing the sheath into the ear, introducing the cannula through the sheath to pierce the tympanic membrane and position the tip adjacent an inner-ear tissue surface; and delivering the composition through the cannula to adhere to the tissue surface.

Abstract: A medicament delivery device includes a housing having distal and proximal ends along a longitudinal axis. The housing is arranged to accommodate a medicament container and a delivery member connected to the container; a reloadable drive mechanism for acting on an accommodated container; a delivery member cover at the proximal end and slidable in relation to the housing along the axis; and a cover lock mechanism that includes a first lock member on an actuator movably arranged in relation to the housing and a second lock member on the cover. The first lock member engages the second lock member to block movement of the cover, and the actuator is movable in relation to the cover such that manually actuating the actuator generally transverse to the axis causes the first lock member to be moved out of engagement with the second lock member, thereby allowing the cover to be moved.

Abstract: An injection device includes a housing having an aperture or window, and a dose indicator positioned within the housing. The dose indicator is rotatable with respect to the housing during dose setting and dose dispensing. The device includes a gauge element interposed between the housing and the dose indicator. The gauge element has a second aperture or window, which is positioned with respect to the first aperture or window such that at least a part of the dose indicator is visible through the first and second apertures or windows. The gauge element is axially guided within the housing and is in threaded engagement with the dose indicator such that rotation of the dose indicator causes an axial displacement of the gauge element. A resilient member provides a force necessary for ejecting a dose from the injection device.

Abstract: An assembly for a drug delivery device is provided, the assembly comprising an actuator which is configured to perform a setting movement in a proximal direction in order to set a dose of a drug, and which is configured to perform a dispense movement in a distal direction in order to dispense a dose of a drug. The assembly further comprises stop mechanism acting after a maximum amount of a drug has been delivered, which is configured to axially constrain the setting movement of the actuator such that the setting of a dose is inhibited, wherein a limited axial movement of the actuator is allowed.

Abstract: A drug delivery device comprises a body component located concentrically within a sleeve, wherein the body component comprises body component thread features and the sleeve comprises sleeve thread features that engage with the body component thread features such that the body component is caused to rotate within the sleeve as the body component and the sleeve component move axially with respect to one another by force of an engaging face of the sleeve thread features against an engaging face of the body component thread features causing sliding of the engaging face of the sleeve thread features over the engaging face of the body component thread features. One of the body component and the sleeve constitutes a first part and the other of the body component and the sleeve constitutes a second part.

Abstract: An automatic injector includes a cover extending along a longitudinal axis. A syringe for injecting a drug is arranged inside the cover, and includes a needle, a needle protector, a body, a plunger, and a rod for pushing the plunger into the syringe body, which is moved axially forwards by a resilient load force exerted by a first spring during an injection. The syringe also includes a tip for protecting the needle, which is axially movable about the needle and against a resilient load force exerted by a second spring between a forward position in which the tip surrounds the needle and a retracted position in which the needle is uncovered. A mechanism blocks the forward movement of the rod. The mechanism is deactivated as the tip is moved towards the retracted position and is reactivated during the injection when the tip is moved towards the forward position.

Abstract: A medical device accessory comprising an interface configured to connect the medical device accessory with a medical device for administration of a medical treatment using the medical device and the medical device accessory, a plurality of electrical contacts proximate the interface, the electrical contacts comprising a lead electrical contact adapted to receive an voltage from a power source associated with the medical device and one or more identifying electrical contacts, and at least one conductor providing an electrical connection between the lead electrical contact and the one or more identifying electrical contacts. An arrangement of the one or more identifying electrical contacts connected to the lead electrical contact identifies a characteristic of the medical device accessory.

Abstract: A drug delivery device for dispensing of a dose of a medicament includes a housing extending in an axial direction and a piston rod to operably engage with a piston of a cartridge to displace the piston in an axial distal direction. The drug delivery device includes a dose indicating mechanism including a first spool and a second spool rotatably supported in the housing and a dose indicating tape coiled onto at least the second spool and fixed with an end to an outer circumference of the first spool. The first and second spools are oriented substantially parallel to each other and substantially parallel to the piston rod.

Abstract: The present invention relates to a drive mechanism for a drug delivery device, comprising: a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal direction during a dose dispensing action, at least one actuation member mechanically coupled with the piston rod to induce a distally directed displacement of the piston rod when actuated by a user, a control to ascertain at least one predefined condition of use, and at least one interlock member coupled with the control to mechanically obstruct displacement of the piston rod if the condition of use is not fulfilled.

Abstract: The method set out herein involves conducting clinical trial to develop parenteral therapeutic product with drug delivery device. The method comprises conducting a dose-finding clinical study using a variable dose drug delivery device to evaluate multiple clinical doses, wherein the variable dose drug delivery device is automatic, portable and for user self-administration. During the dose-finding clinical study, both the performance of the drug and the performance of the variable dose drug delivery device are evaluated.

Abstract: A fluid dispenser comprising: a fluid reservoir (1); and a pump (3) comprising a pump body (30) and an actuator rod (34), defining between them a pump chamber (33) having a predetermined maximum volume, the rod (34) being axially movable in the body (30) so as to vary the volume of the pump chamber (33); the dispenser being characterized in that it further comprises a dispenser cannula (5) that is mounted on the actuator rod (34) and that includes a dispenser outlet (52) that is suitable for forming a drop of fluid that separates from the cannula (5) by gravity, the determined maximum volume of the pump chamber (33) being substantially equal to the volume of the drop of fluid that is dispensed at the dispenser outlet (52).

Abstract: Methods and devices to quickly and accurately apply medication to a paranasal sinus are disclosed. Additionally, the methods and devices prevent the medication applied to a paranasal sinus from flowing down a patient's throat by expanding, using an inflation lumen of a device, an expandable member of the device adjacent to the patient's choana.

Abstract: Various embodiments enable an introducer for a catheter to be rotated around an axis and/or traversed backward and/or forward along the axis. In various embodiments, positioning of an introducer may be enabled by an introducer support configured to be rotated around an axis and/or extended or retracted along the axis. The introducer may be manually operated and/or operated by motors in a nose cone of a catheter positioning system. In various embodiments, a portion of the introducer support may be configured to flex. In other embodiment, positioning of an introducer may be enabled by an adjustable nose cone of a catheter positioning system.

Abstract: An assembly for a drug delivery device (200) is presented which comprises a housing (24) having a proximal end (25) and a distal end (26), a cartridge, a plunger (19) which is movably retained in the cartridge (14) and a piston rod (6). The assembly further comprises a rod displacement feature (33). The assembly is configured such that, in an initial state of the assembly, the piston rod (6) and the rod displacement feature (33) are arranged such that movement of the rod displacement feature (33) from the first position to the second position is transferred to the piston rod (6) such that the piston rod (6) is moved with respect to the cartridge (14) and the assembly is switched from the initial state to a primed state. In the primed state, movement of the rod displacement feature (33) from the first position to the second position is not transferred to the piston rod (6).

Abstract: A cartridge engageable with a medical device, the method of making a cartridge comprising an ordered arrangement of N electrical components each with different respective values of an electrical property, and an ordered arrangement of N conductors operably coupled to the ordered arrangement of the N electrical components. A medical device is arranged to receive a cartridge comprises for each of N conductors on the cartridge, at least a first respective contact arranged to electrically couple with the corresponding conductor when the cartridge is engaged with the medical device; the medical device also comprises an evaluation means operable to evaluate the different respective values of an electrical property of N electrical components on the cartridge, wherein the N electrical components form an ordered arrangement which is operably coupled to the N conductors on the cartridge, and a switching arrangement operable to selectively electrically couple a respective pair of contacts to said evaluation means.

Abstract: An optical sensor for a delivery device having a piston that displaces a substance, such as a fluid, from a reservoir. The optical sensor has a light source and a detector array for imaging encoding features disposed along a plunger rod coupled to the piston. By virtue of the pattern of encoding features, an absolute position of the plunger rod relative to a fiducial position may be determined uniquely. Thus, the volume of fluid remaining in the reservoir, the rate of fluid delivery, and proper loading of the reservoir may be accurately ascertained. Additionally, the encoding may serve to uniquely identify a version of the reservoir which may be supplied in various versions corresponding, for example, to differing concentrations of a therapeutic agent to be dispensed.

Abstract: A counter system for use in a drug delivery device is provided. The counter system comprises a counter element which is a foil, the counter element comprising indentations and indicia associated with the indentations, and a drive member provided with a catch for driving the counter element, wherein the catch engages a first indentation, and wherein, the catch is configured such that, when the drive member moves in a first direction, the counter element does not move and the catch disengages the first indentation and engages a second indentation which is arranged adjacent to the first indentation, and when the drive member moves in a second direction which is opposite to the first direction, the counter element also moves in the second direction.

Abstract: An assembly for a drug delivery device includes a guide track and a spring member. A first section of the guide track defines an angular start position for a guide feature of the dose member and a second section of the guide track defines an axial stop position for the guide feature. When the dose member is rotated in a dose setting direction, the guide feature is angularly displaced from the angular start position towards a connection region of the guide track, the spring member is torsionally biased by the spring member towards the angular start position. When the guide feature passes the connection region, the guide feature enters the second section and is axially displaced towards the axial stop position in which reduction of the torsional bias is prevented by mechanical cooperation of the guide feature and the second section.

Abstract: A method and system for detecting information related to a drug reservoir. The method includes transmitting energy at a coded material disposed on a drug reservoir, where the energy has at least one predefined characteristic. The coded material identifies information related to the drug reservoir. The coded material modifies the energy and emits the modified energy to a receiver. The method further includes receiving at the receiver the modified energy. The method further includes determining information related to the drug reservoir based on the modified energy as the drug reservoir is loaded into a drug delivery device.

Abstract: A medical device accessory comprising an interface configured to connect the medical device accessory with a medical device for administration of a medical treatment using the medical device and the medical device accessory, a plurality of electrical contacts proximate the interface, the electrical contacts comprising a lead electrical contact adapted to receive an voltage from a power source associated with the medical device and one or more identifying electrical contacts, and at least one conductor providing an electrical connection between the lead electrical contact and the one or more identifying electrical contacts. An arrangement of the one or more identifying electrical contacts connected to the lead electrical contact identifies a characteristic of the medical device accessory.

Abstract: A valve is provided for controlling flow along a fluid line that includes an outer shell and an inner housing slidably disposed therein that includes connector threads surrounding a boss on one end and a passage through the boss. A backing member is coupled to the outer shell and has a sealing pin extending into the passage. The inner housing is movable helically relative to the outer shell from a closed position wherein a sealing pin engages an outlet opening at the distal end of the boss to seal the opening and an open position in which the inner housing is directed away from the sealing pin to open a fluid path through the valve. A torque limiter mechanism between the outer shell and inner housing resists movement from the valve closed position to the valve open position until a selected torque level is reached.

Abstract: A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.

Abstract: The invention relates to an injection unit, preferably a pen-shaped injection unit, for administering or delivering a fluid product. The injection unit comprises a housing, an axially movable piston rod mounted in the housing in a non-rotatable manner, a delivery apparatus having a threaded nut that is able to move the piston rod in order to deliver product, a dosing device having a dosing sleeve, a rotary knob, a discharge button arranged coaxially on the dosing sleeve, and a receptacle for the product. The dosing device is connected to the delivery apparatus via a coupling mechanism, wherein the coupling mechanism includes of at least two coupling surfaces that each carry a toothing comprising teeth, wherein the coupling surfaces are used to generate an acoustic and/or tactile signal corresponding to the set or corrected dose of the product to be administered during the dosing operation or during correction of the dose.

Abstract: A drive assembly for a medication delivery device is provided, comprising a piston rod which is movable from a start position to an end position for medication delivery and resettable from the end position to the start position. The drive assembly further comprises an impeding element for impeding a movement of the piston rod from the end position to the start position during a reset of the piston rod, wherein the impeding element comprises at least one resilient element. Furthermore, a medication delivery device comprising the drive assembly is disclosed.

Abstract: A dose setting mechanism for a medicament delivery device is presented having a locking feature that reliably and consistently unlocks a dose injection button and concurrently a lead screw when the dose setting mechanism is transitioned from a non-activated state to an activated state. This locking feature uses dose member assembly having a rotational biasing element combined with concentric inner and outer sleeves interfacing with a locking member.

Abstract: A dose setting mechanism for a drug delivery device is provided comprising a dose setting member and a further element. Maximum dose stop features are provided on a housing and on the further element.

Abstract: A syringe including a barrel having an internal reservoir for containing a volume of medication, a plunger received within the barrel and axially movable relative thereto to change the volume of medication in the reservoir, and a dosage indicator movable with the plunger, the dosage indicator in contact with the barrel such that at least one of an audible alert and a tactile alert is produced upon movement of the dosage indicator relative to the barrel.

Abstract: The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.

Abstract: A medication injection pen is provided comprising a housing (218), for housing a dose set knob (220), a leadscrew (226), a driver (224), a setback member (222), and a dose stop member (228). The dose set knob (220) is rotatable with respect to said housing (218) to set a desired injection dose, and comprises at least one internal thread (291). The leadscrew (226) includes a thread element by which it is advanceable in a first direction via a corresponding thread engagement, said first direction being that which expels medication from a cartridge (36). The driver (224) is rotationally fixed to said leadscrew (226) for preventing relative rotation therebetween, said driver (224) being rotatable in a first direction to rotate and advance said leadscrew (226) in said first direction. The setback member (222) is rotationally fixed to said driver (224) for preventing relative rotation therebetween.

Abstract: A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.

Abstract: A dose setting mechanism for a medicament delivery device is presented having a pinion mounted to a locking member where the axis of rotation of the pinion is offset and parallel to the longitudinal axis of the housing containing the dose setting components. Primary and secondary dose members are engaged with the pinion to indicate a set dose of medicament.

Abstract: Drive and metering devices for injection devices include a dose display element with a helical dosage scale; an indicating means; a metering member, which can be rotated relative to the indicating means for dose setting; a discharge spring and an advancement member. The dose display element can be screwed relative to the indicating means about a longitudinal axis (L) and a value on the dose scale can be read via the indicating means corresponding to the set dose. The discharge spring causes the advancement member to discharge the product as it moves an overall discharge stroke length (Hg), where the overall discharge stroke length (Hg) comprises a first partial discharge stroke length (H1), during which the dose display element is rotationally secured in relation to the indicating means and where the dose display element can be rotated relative to the indicating means following the first partial discharge stroke length (H1).

Abstract: Device for medicament delivery with syringe-like usability having a locking mechanism. A device for medicament delivery with syringe-like usability with at least one grip (30), at least one plunger rod (20) being substantially rotationally fixed relatively to the grip, and at least one locking mechanism (17) configured to substantially inhibit movement of the plunger rod in a longitudinal direction of the device for dose delivery when being in at least one locking position. The locking mechanism comprises at least one rotatable part (40) that is substantially fixed in a longitudinal direction, that is rotatable relatively to the grip, and that interacts with the plunger rod. The device comprises at least one indicator drum (60).

Abstract: The switch housing for capacitive switches has an outer contact surface and flat electrode structures which are arranged on the inside and in a position opposite the contact surface and which are placed by two-component injection molding in recessed regions of the housing body injected from a first, electrically non-conductive plastic component by a second, electrically conductive plastic component. Preferably, both plastic components are a polycarbonate, the second plastic component containing carbon fibers.

Abstract: A supplemental device for gathering information concerning the use of an injection device, the supplemental device having a first camera sensor portion for generating a first camera output indicative of a scene in the field of view of the first camera sensor portion, a second camera sensor portion for generating a second camera output indicative of a scene in the field of view of the second camera sensor portion, and at least one processor. The processor configured to use the first camera output to determine whether a rotational speed of an object in the field of view exceeds a threshold speed, if it is determined the rotational speed of the object does not exceed the threshold speed, to process the second camera output to identify a feature provided on the or another object, and if it is determined the rotational speed of the object does exceed the threshold speed, to refrain from attempting to identify the feature.

Abstract: An ambulatory infusion device includes a common module having a pump mechanism and a fluid flow path in communication with the pump mechanism. The device also includes a custom module operably coupleable to the common module. The custom module includes a reservoir for housing a liquid composition comprising a medicament and control electronics. The reservoir is configured to fluidly couple with the fluid flow path, and the control electronics are configured to electrically couple to the pump mechanism when the common module and the custom module are operably coupled. When the common module and the custom module are operably coupled, the pump mechanism is configured to drive the liquid composition from the reservoir to a patient via the fluid flow path, and the control electronics are configured to control the rate at which the pump mechanism drives the liquid composition.

Abstract: The invention relates to a detent mechanism for controlling translation between two components in a longitudinal direction (P, D), the detent mechanism comprising at least one clip on one of the components arranged to be in a ramped engagement with a recess in the other one of the components in an initial state in such a manner that translation between the components is constrained and that application of a translative force between the components in one longitudinal direction (P, D) with the clip engaged with the recess deflects the clip out of the recess when a predetermined value of the translative force, at least depending on the resilience of the clip, is overcome so as to allow translation between the components.

Abstract: A drug delivery system (1) comprising first (35) and second reservoir units (30) with first and second identifiers (32), and a main unit (10) adapted to receive either of the first (35) and second reservoir units (30) in a mounted position. The main unit (10) comprises drug expelling means having dose setting means (11, 1, 14, 15, 19) comprising a rotational dose setting member allowing a user to set a desired dose size for the given drug, the dose size being set in fixed increments for a given state. The drug expelling means has a first state in which an increment corresponds to a first volume of drug, and a second state in which an increment corresponds to a second volume of drug, wherein the drug expelling means is set in the first state by means of the first identifier when a first reservoir unit is mounted, and the drug expelling means is set in the second state by means of the second identifier when a second reservoir unit is mounted.