Including Means For Controlling Piston Stroke Length Patents (Class 604/208)
  • Publication number: 20140276592
    Abstract: The embodiments disclosed herein relate to lockable syringe assemblies and related devices and methods. The syringe assembly may include a barrel, a plunger, and a locking mechanism. In some arrangements, the locking mechanism is an elastomeric locking ring or a rigid partial ring. The plunger may include a plurality of ribs and is longitudinally moveable within the barrel. Once the plunger is disposed at a desired longitudinal location, the plunger can be axially rotated and locked in such a way that further longitudinal movement is restricted.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Inventors: Jim Mottola, Darla Gill, Gregory R. McArthur
  • Patent number: 8834431
    Abstract: An injection device having a delivery element with an inner thread may be driven by rotation and includes a cylindrical outer wall region, which is substantially smooth. Such features provide a delivery element configured such that it is less intimidating to patients than known threaded rods, and may facilitate easy cleaning. The delivery element may be non-rotatably guided and axially spring-loaded, and may be inserted axially into the housing when the reservoir is replaced. The driving thread element for the delivery element may be mounted in the vicinity of the distal end of the housing.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: September 16, 2014
    Assignee: TecPharma Licensing AG
    Inventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
  • Publication number: 20140236096
    Abstract: A drug delivery device is provided comprising a housing comprising a distal end and a proximal end and a cartridge adapted and arranged to contain at least one dose of a drug, a bung being movably arranged within the cartridge. In an initial state of the device, the bung is arranged in a proximal end position with respect to the cartridge. The device further comprises a piston rod adapted and arranged to move the bung in the distal direction with respect to the cartridge for delivering a dose of the drug. The device further comprises a mechanism operable such that, after a dose delivery operation was completed, the piston rod is moved into the proximal direction with respect to the bung by a back off distance (D), wherein in the initial state, a distance between a distal end of the piston rod and a proximal end of the bung is greater than zero, with the distance between the piston rod and the bung in the initial state being defined by the back off distance (D).
    Type: Application
    Filed: September 27, 2012
    Publication date: August 21, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Michael Helmer, Christoph Eisengarthen, Winfried Huthmacher, Carsten Mosebach
  • Patent number: 8801675
    Abstract: Medical devices comprising a syringe barrel and a two-piece plunger rod are provided. According to one or more embodiments, the two-piece plunger rod includes a distal portion and proximal portion slidably mounted to the distal portion. The distal and proximal portions include a tab and plurality of grooves which engage to adjust the overall length of the plunger rod to a plurality of locked lengths. The locked lengths of the plunger rod permit varying amount of fluid to be expelled from the barrel.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: August 12, 2014
    Assignee: Becton Dickinson France, S.A.S.
    Inventors: James Janish, Mark Sebree, Glenn D. Kopf
  • Publication number: 20140213985
    Abstract: The present invention relates to a drug delivery device for administering a dose of a medicinal product, comprising: a dose setting and injection mechanism adapted to be operably engaged with a piston of a cartridge containing the medicinal product, at least two housing components being directly and releasably interconnectable to each other, and a flexible coupling means separately coupled to any of said housing components and being adapted to keep the housing components within a predefined spatial range when they are disconnected.
    Type: Application
    Filed: September 6, 2012
    Publication date: July 31, 2014
    Applicant: Sanofi SAentis Deutschland GmbH
    Inventors: Axel Teucher, Michael Jugl, German F. Hamm
  • Publication number: 20140194830
    Abstract: An assembly for a drug delivery device, comprising: a housing having a distal end and a proximal end, a piston rod, a drive member, the drive member being moveable in a proximal direction with respect to the housing and with respect to the piston rod for setting a dose of a drug, at least one stop member which is provided on one of the piston rod and the drive member and which is radially moveable with respect to the one of the piston rod and the drive member on which it is provided, and at least one interaction member which is provided on the other one of the piston rod and the drive member. Furthermore, a piston rod for a drug delivery device is provided.
    Type: Application
    Filed: February 27, 2014
    Publication date: July 10, 2014
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Philippe Nzike, Steffen Raab, Uwe Dasbach, Uwe Boeser, Ulrich Brüggemann, Francisco Soares
  • Publication number: 20140194826
    Abstract: A drug injector (1) comprising expelling means for expelling a dose of drug from a reservoir, a release member (13) for releasing the drug expelling means, and an actuation member (33) adapted to be moved by a user between an initial, intermediate and actuated position in which the release member is moved to release the drug expelling means. The injector further comprises an electronic capturing system for capturing data representing a dose of drug to be expelled, and a switch (38) for starting initialization of the data capture system, the switch being actuated when the actuation member is positioned in its intermediate position. A spring (34) provides a biasing force against movement of the actuation member between its initial and intermediate position. Thereby the electronic data capturing system is allowed to initialize during the actuation member's movement between the intermediate and the actuated position.
    Type: Application
    Filed: July 9, 2012
    Publication date: July 10, 2014
    Applicant: NOVO NORDISK A/S
    Inventors: Ole Christian Nielsen, Morten Soerensen
  • Patent number: 8771239
    Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: July 8, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Malcolm Boyd, Richard Letham, David Plumptre, Robert Veasey, James May
  • Publication number: 20140180217
    Abstract: A limiter for a dispensing device is provided. The limiter includes a body (20) arranged to mount with at least a portion of a dispensing device (300), and a stop extending from the body. The stop (40) is configured to permit movement a plunger of the dispensing device a predetermined distance in a dispensing direction correlated to a desired volume of medium to be delivered from the dispensing device. The stop is configured to prevent further movement of the plunger in the dispensing direction, thereby limiting the amount of medium delivered from the dispensing device. The dispensing device may be a syringe.
    Type: Application
    Filed: April 16, 2012
    Publication date: June 26, 2014
    Inventors: John Kuczek, Clive Patience, Donovan Quinn, Lucio Giambattista
  • Publication number: 20140180245
    Abstract: Devices that guide the accurate loading and dispensing of predetermined doses of fluid from injection syringes are disclosed.
    Type: Application
    Filed: April 25, 2012
    Publication date: June 26, 2014
    Applicant: ICON BIOSCIENCE, INC.
    Inventors: Vernon G. Wong, Tan Pham, William S. White, Glenn T. Huang, Mae W. Hu
  • Publication number: 20140163478
    Abstract: The present invention relates to a drug delivery device for setting and dispensing a dose of a medicament, comprising: a body to accommodate a drive mechanism having a piston rod, a cartridge having a barrel sealed by a piston slidably displaced therein along an axial direction, wherein the cartridge is directly connectable with the body by way of an interface, and wherein the barrel comprises at least one radially extending portion at its outer periphery to cooperate with at least one further functional component of the device.
    Type: Application
    Filed: July 19, 2012
    Publication date: June 12, 2014
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Hendrik Hoppe, Clemens Josef
  • Patent number: 8740857
    Abstract: A medical delivery system comprising a container and a coupling mechanism movable between a coupling position wherein distal movement of a drive mechanism is transferred to an actuator, and a non-coupling position wherein distal movement is not transferred to the actuator. Moreover the present invention relates to a dosing assembly for use in the medical delivery system and a container for use in the medical delivery system. Finally, the present invention relates to medical delivery system comprising a dosing assembly having means for preventing a drive stem of the dosing assembly from being moved in a distal direction.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: June 3, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Asger Voss Christiansen, Jonas Torry-Smith, Michael Ejstrup Hansen, Nikolaj Eusebius Jakobsen, Ramin Nateghi Elahi, Claus Schmidt Møller, Claus Urup Gjødesen
  • Patent number: 8740860
    Abstract: An assembly for a drug delivery device comprises a housing having a proximal end and a distal end, a dose button configured to be moved with respect to the housing for setting and delivering a dose of a drug, and a resilient setting member. For a dose delivery movement, the dose button is arranged to be moveable in the distal direction with respect to the housing from a dose delivery position, thereby deforming the resilient setting member to store energy in the resilient setting member. The assembly is configured to use the energy stored in the resilient setting member for a dose setting movement to move the dose button in the proximal direction with respect to the housing into the dose delivery position. Furthermore, a drug delivery device is provided.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: June 3, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Axel Theucher
  • Patent number: 8721600
    Abstract: A delivery gun for discharging bone cement from a cartridge that includes a piston. The gun has a casing from which a drive rod and a disk extend. A drive assembly advances the drive rod and disk so that disk displaces the piston causing the discharge of cement. The drive assembly includes plural links that are pivotally connected to a trigger. The links are displaced in response to the manual displacement of a trigger. One of the links is configured to selectively engage the drive rod. When this particular link is engaged with the drive rod and displaced, the drive rod the drive rod is advanced at a first speed. When this link does not is not engaged with the drive rod, the drive rod is advanced by another link at a second speed.
    Type: Grant
    Filed: November 30, 2012
    Date of Patent: May 13, 2014
    Assignee: Stryker Corporation
    Inventors: Bruce Henniges, Christopher S. Brockman, Marshall K. Proulx
  • Patent number: 8721604
    Abstract: An assembly for a drug delivery device is provided comprising a housing having a distal end and a proximal end, a dose button configured to be moved with respect to the housing for setting and delivering a dose of a drug from the device, and a blocking member. The blocking member is adapted and arranged to be releasably coupled to the housing such that, when the blocking member is coupled to the housing, movement of the dose button with respect to the housing is prevented. Furthermore, a drug delivery device is provided.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: May 13, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventor: Axel Theucher
  • Publication number: 20140128843
    Abstract: The present invention relates to a drug delivery device for setting and dispensing of a dose of a medicament is presented comprising a housing to accommodate a cartridge filled with the medicament, an electrically operated drive mechanism to be operably engaged with the cartridge to expel a predefined dose of the medicament from the cartridge, and at least one dose element displaceably arranged relative to the housing to set and/or to dispense the dose of the medicament, wherein the dose element and the drive mechanism are mechanically decoupled from each other.
    Type: Application
    Filed: July 12, 2012
    Publication date: May 8, 2014
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Alex John Baker, James Andrew Holt, Timothy Lewis Sharpe
  • Patent number: 8701507
    Abstract: An improved metering apparatus includes a metering pipette (1) and a metering attachment (2). The metering pipette (1) includes a metering body (3) and a piston (4) which is longitudinally displaceably guided in the metering body (3). The metering attachment (2) is connected or connectable to the metering pipette (1). It includes a stop body (16) having a stop (17) for the piston (4) (FIG. 2).
    Type: Grant
    Filed: September 28, 2010
    Date of Patent: April 22, 2014
    Assignee: elm-plastic GmbH
    Inventors: Birgit Lonien, Sascha Moehs
  • Patent number: 8672897
    Abstract: A medical delivery system (100) comprising a container (102) which is adapted to be fastened to a dosing assembly (104). One of the container and the dosing assembly comprises a rotatable element (106) adapted to cooperate with the other one of the container and the dosing assembly, so as to lock/fasten the container to the dosing assembly. Furthermore, the present application relates to a container and a dosing assembly for use in the medical delivery system.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: March 18, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Ramin Nateghi Elahi, Jonas Torry-Smith, Michael Ejstrup Hansen, Nikolaj Eusebius Jakobsen
  • Publication number: 20140074039
    Abstract: A medical injector is provided herein which includes first and second body portions each having a longitudinal axis and configured to couple at a coupling. The medical injector also includes an axially-displaceable plunger; biasing element for advancing the plunger a predetermined distance; and, a releasable retainer for releasably retaining the plunger in a first state against the force of the biasing element. In an initial state, the axes of the first and second body portions are not aligned and the plunger is in the first state. In a coupled state, the axes of the first and second body portions are axially aligned, and the releasable retainer releases the plunger, thereby allowing the biasing element to advance the plunger the predetermined distance. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon assembly of the pen injector, thereby minimizing premature or failed activations.
    Type: Application
    Filed: October 30, 2013
    Publication date: March 13, 2014
    Applicant: BECTON, DICKINSON AND COMPANY
    Inventors: RUANE S. JETER, RICHARD A. CRONENBERG, LIONEL VEDRINE, ATUL PATEL
  • Patent number: 8647309
    Abstract: The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: February 11, 2014
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Harms, James Robert Howarth, Robin Craig Cocker, George Richard Gregory, Anthony Raymond Charpentier, Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 8641683
    Abstract: An injection device for injection of set doses of medicine from a cartridge has a nut that is screwed up along a threaded piston rod during a dose setting operation. The nut is screwed along the piston rod by rotating a dose setting member. A rotational coupling mechanism includes an axially displaceable coupling member which is rotated as a function of axial displacement. During dose setting, the nut is allowed to rotate relative to the coupling member. During injection, the coupling member is rotationally locked to the nut. This provides a dose setting and injection mechanism wherein the nut member is both rotated during dose setting and during injection.
    Type: Grant
    Filed: February 28, 2012
    Date of Patent: February 4, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Kristian Glejbol, Steven Linnebjerg, Claus Schmidt Moller, Michael Ejstrup Hansen
  • Patent number: 8641682
    Abstract: An applicator, for example an injector (100), includes a flow control means including a first member (2) and a second member (6) for controlling flow from an inlet (4) to an outlet (5). A hinged linkage (17) is provided having a first end (18) rotatably engaged with the first member and a second end (19) rotatably engaged with the second member. The linkage (17) is moveable between a collapsed position and an over-center locked position which prevents relative movement of the first member (2) towards the second member (6). Linkage unlocking means (28) are provided which move the hinge (22) away from the over-center locked position so that the first and second members can be moved together. A similar linkage (10) prevents unwanted movement of a needle shroud (8). A needle shroud (8) which can be used to remove the needle (7) from the injector (100) is also described.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: February 4, 2014
    Assignee: Simcro Tech Ltd.
    Inventors: Rodney G. Walker, Todd D. Ebbett, Colin A. Standing
  • Publication number: 20140031763
    Abstract: The syringe includes first and second outer cylinders having a flowing port at a distal end through which liquid is flowable, and a plunger inserted from the proximal side of the outer cylinder. The syringe includes a tooth portion provided along the direction of movement of the plunger, and a hook configured to lock the tooth portion at a predetermined locking position and prevent the movement of the plunger in the direction toward the proximal end. The hook retracts from the locking position in association with the unlocking operation and restores automatically to the locking position after the unlocking operation.
    Type: Application
    Filed: September 30, 2013
    Publication date: January 30, 2014
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Katsuaki Soma, Akihiro Takahashi
  • Patent number: 8633016
    Abstract: A microbial detection assembly is disclosed which includes a tubular body, a pierceable septum, and a plunger. The tubular body defines a longitudinal axis and has a first end and a second end. The pierceable septum is configured to seal the first end of the tubular body. The plunger head is configured to substantially close the second end of the tubular body. Together, the plunger head, the pierceable septum, and the tubular body define a reservoir dimensioned to receive a medium and a sample substance. Additionally, the plunger head is positioned and is movable within the tubular body in response to changes in pressure within the reservoir.
    Type: Grant
    Filed: September 23, 2009
    Date of Patent: January 21, 2014
    Assignee: Covidien LP
    Inventor: Jonathan G. Parker
  • Patent number: 8632507
    Abstract: An auto-injection device has a housing with a medicament container disposed within; a dose setting mechanism for setting a dose of a medicament; a drive nut and a plunger rod operably connected, with an energy accumulator operably connected to the dose setting mechanism; and an activating mechanism and a positioning mechanism operably connected to the plunger rod for locking the plunger rod from being displaced. The positioning mechanism includes a locking nut arranged to cooperate with fixed, flexible locking features for locking the locking nut from rotation. A resilient member arranged inside the plunger rod is configured to allow the plunger rod to be resiliently and axially displaced when the locking nut is unlocked.
    Type: Grant
    Filed: February 3, 2009
    Date of Patent: January 21, 2014
    Assignee: SHL Group AB
    Inventor: Istvan Bartha
  • Patent number: 8632506
    Abstract: A medical delivery system comprising a container (202) for accommodation of a medicament and a dosing assembly (204) adapted to be fastened to the container. The medical delivery system comprises a coding mechanism for ensuring that only a predetermined container can be fastened to a predetermined dosing assembly. A container for use in the medical delivery system. A dosing assembly for use in the medical delivery system.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: January 21, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Søren Steenfeldt-Jensen, Thomas Pedersen, Michael Ejstrup Hansen
  • Patent number: 8632505
    Abstract: The invention provides a syringe accessory device for adjustment of a predefined partial syringe dosage comprises a recess (10) for receiving a syringe body (14). Additionally, within a single portion (12) a slot (16) is located. Within the slot (16) a syringe flange (18) or finger grip can be held. To obtain a predefined dosage of liquid within the chamber of the syringe body (14), a plunger (26) is pressed in the chamber (14) in the direction of the arrow (38) until the plunger head (44) contacts a stopping means (24) whereby the stopping means is performed by a stopping surface (24) of the single portion (12). The invention further provides a kit comprising said syringe accessory device and its use for adjusting defined liquid dosages in syringes.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: January 21, 2014
    Assignee: Novartis Vaccines & Diagnostics, GmbH
    Inventor: Mathias Fibi
  • Publication number: 20140018770
    Abstract: Various handheld medical dispensing configurations and methods including the following. Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance.
    Type: Application
    Filed: July 16, 2012
    Publication date: January 16, 2014
    Inventor: Howard Sutkin
  • Patent number: 8617123
    Abstract: A pre-filled vial assembly adapted for dispensing and delivering a fluid includes: a body member having a distal end, a proximal end, and a sidewall extending therebetween defining an interior; and a transitionable stopper disposed within the interior of the body member. At least a portion of the body member is engageable with a source of air or fluid for advancing the transitionable stopper from an initial position to an activated position in which at least a portion of a fluid contained within the interior of the body member is advanced therefrom.
    Type: Grant
    Filed: August 20, 2010
    Date of Patent: December 31, 2013
    Assignee: Becton Dickinson France, S.A.S.
    Inventors: Tracy Ray Hottovy, Eric Schiller
  • Patent number: 8617124
    Abstract: The present invention relates to a medicament delivery device comprising an elongated housing arranged to contain a medicament container which medicament container contains a number of doses; a dose counter mechanism comprising a dose drum arranged with dose indicia on its outer surface and visible through a window on said housing; a rotatable driver connected to said dose drum; a plunger rod arranged to act on said medicament container for expelling a dose of medicament; an actuation mechanism connected to said rotatable driver and to said plunger rod when said medicament delivery device is actuated; wherein said dose drum is arranged with internal threads, in engagement with corresponding threads on said driver, wherein said threads have a certain pitch; wherein said dose drum is also arranged with external threads in engagement with corresponding threads arranged fixed in relation to said housing, wherein said threads have a certain pitch; and wherein the pitch of the threads between the dose drum and fixe
    Type: Grant
    Filed: July 5, 2010
    Date of Patent: December 31, 2013
    Assignee: SHL Group AB
    Inventors: Anders Wieselblad, Kenny Kai Fung Cheung
  • Patent number: 8613731
    Abstract: A dosing assembly (204) and/or a container (202) comprising fastening means (206,208) for fastening the container to the dosing assembly, the fastening means of the dosing assembly and/or the container defining an asymmetrical pattern in a plane transverse to an axial direction of the dosing assembly and/or a container.
    Type: Grant
    Filed: July 15, 2007
    Date of Patent: December 24, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Michael Ejstrup Hansen, Søren Steenfeldt-Jensen, Thomas Pedersen, Claus Schmidt Møller
  • Patent number: 8613720
    Abstract: The present invention is directed to an automatic reconstitution drug delivery device. The inventive device effects simple and automatic reconstitution of a dry drug. To effect reconstitution, a user displaces a release button which causes first and second chambers of a drug cartridge to communicate, resulting in automatic mixing of a diluent and dry drug to effect reconstitution of the dry drug. The user then simply sets the dose volume using a dose-setting mechanism, and administers the injection in a manner typical of self-injection drug delivery devices. Whole or partial automatic priming can be also achieved by the device.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: December 24, 2013
    Assignee: Becton Dickinson and Company
    Inventors: Antonio Bendek, John Laiosa
  • Patent number: 8608709
    Abstract: The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a dose setting member (20, 70) which is screwed out from the housing (30) to set a dose and pushed axially back to the housing (30) in order to expel the set dose. A scale drum (80) is axially and inrotatable coupled to the dose setting member (20, 70) such that the scale drum (80) is rotated up a thread (34) when the dose setting member (20, 70) is rotated to set a dose. When the dose setting member (20, 70) is pushed axially back to its initial position to inject the set dose, the scale drum (80) is released from its inrotatable connection in order to allow the scale drum (80) to rotate down the thread (34) and back to its zero position.
    Type: Grant
    Filed: October 6, 2005
    Date of Patent: December 17, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Claus Schmidt Møller, Klaus Thøgersen
  • Patent number: 8608708
    Abstract: An injector apparatus includes a housing (101, 102) for a cartridge or syringe, a plunger (40) for cooperating in use with the cartridge or syringe to express successive doses, a dose setting arrangement (16, 20) to select a dose volume, and a drive mechanism (22, 24) releasable to advance the plunger in respective predetermined increments of magnitude to express the successive doses. The drive mechanism includes a drive spring (22) for imparting movement directly or indirectly to the plunger (40), and the dose setting arrangement includes a dose setting element (16) moveable in a dose setting routine to define a magnitude of an increment of movement of the plunger for a given dose. The drive mechanism further includes a clutch arrangement (56) operable during the dose setting routine to inhibit forward movement of the plunger and/or to isolate the dose setting element from the force of the drive spring.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: December 17, 2013
    Assignee: Owen Mumford Limited
    Inventor: Toby Cowe
  • Patent number: 8585657
    Abstract: Some embodiments of an infusion pump system include a drive system that advances a piston rod to dispense medicine to a user. Moreover, the drive system can be configured to reliably dose selected amounts of medicine to the user while also reducing the likelihood of inadvertent dispensing of medicine in response to impacts or pressure changes exerted upon the infusion pump system.
    Type: Grant
    Filed: June 21, 2011
    Date of Patent: November 19, 2013
    Assignee: Asante Solutions, Inc.
    Inventor: Joshua Colton
  • Patent number: 8588900
    Abstract: The perivascular leak repair system, and method of using the same, of the present invention provides a sealant reservoir with a repair catheter operably attached; a flow control device disposed between the sealant reservoir and the repair catheter, and the flow control device responsive to a flow control signal; a heart phase detector generating a diastole phase signal; an injection switch generating a injection signal; and a flow controller responsive to the diastole phase signal and the injection signal, and generating the flow control signal. A method of sealing a perivascular leak comprises identifying the perivascular leak; inserting a repair catheter to the perivascular leak; injecting sealant at the perivascular leak; and removing the repair catheter. The sealant can be injected when the heart is in diastole to sweep the sealant into the perivascular leak.
    Type: Grant
    Filed: December 6, 2011
    Date of Patent: November 19, 2013
    Assignee: Medtronic Vascular, Inc.
    Inventors: Jeffrey Allen, David Brin, Chris Coppin
  • Patent number: 8585656
    Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.
    Type: Grant
    Filed: May 27, 2010
    Date of Patent: November 19, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Aubrey Plumptre, Christopher John Jones, Robert Frederick Veasey
  • Patent number: 8579868
    Abstract: A medical delivery system (200) having a container (202) and a dosing assembly (204), where the container is fastenable to the dosing assembly by a movement comprising a translatory movement followed by a rotational movement. One of the container and the dosing assembly comprises one or more blocking elements (207) movable between a blocking position and a non-blocking position responsive to the rotational movement. Each blocking element is able to engage the other one of the container and the dosing assembly. A container suitable for use in said medical delivery system.
    Type: Grant
    Filed: July 15, 2007
    Date of Patent: November 12, 2013
    Assignee: Novo Nordisk A/S
    Inventor: Asger Voss Christiansen
  • Patent number: 8579867
    Abstract: A medication delivery device comprising a housing, a medication receptacle, a piston rod which is moveable distally, and a drive device for rotating the piston rod in a first rotational direction. The piston rod comprises two threaded sections, a first threaded section for threaded engagement with a reset element and a second threaded section for threaded engagement with the drive device. In an operational state, the reset element is prevented from rotating and the piston rod prevented from moving proximally. In a resetting state, the reset element is allowed to rotate, such that the delivery device is resettable by rotating the piston rod and the reset element in a second rotational direction and moving the piston rod proximally.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: November 12, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Harms, Steffen Raab, Dominic George Webber, James Robert Howarth, Trevor John Beckett, Geoffrey Philip Gray, John David Cross
  • Patent number: 8562544
    Abstract: A pen type device for ultrasound guided fine needle aspiration cytology and biopsy comprises a hollow body having a needle hole, a sliding part slidably mounted inside the body, elastic members mounted inside the body, a syringe having a cylinder mounted, a rotating part disposed inside the sliding part and the body, a head screw-coupled to the rear end of the sliding part and drawn out from the body, and a negative pressure generating part mounted on the body to generate negative pressure to the syringe by pulling a piston of the syringe when a button located on the outer face of the body is pushed.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: October 22, 2013
    Inventor: Hyuk Ho Kwon
  • Publication number: 20130274680
    Abstract: A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
    Type: Application
    Filed: June 4, 2013
    Publication date: October 17, 2013
    Applicant: DCA DESIGN INTERNATIONAL LTD
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 8556864
    Abstract: A drive mechanism suitable for use in drug delivery devices is disclosed. The drive mechanism may be used with injector-type drug delivery devices, such as those permitting a user to set the delivery dose. The drive mechanism may include a housing, a dose dial sleeve, and a drive sleeve. A clutch is configured to permit rotation of the drive sleeve and the dose dial sleeve with respect to the housing when the dose dial sleeve and drive sleeve are coupled through the clutch. Conversely, when the dose dial sleeve and drive sleeve are in a de-coupled state, rotation of the dose dial sleeve with respect to the housing is permitted and rotation of the drive sleeve with respect to the housing is prevented. In the de-coupled state, axial movement of the drive sleeve transfers force in a longitudinal direction for actuation of a drug delivery device.
    Type: Grant
    Filed: March 30, 2011
    Date of Patent: October 15, 2013
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Publication number: 20130267906
    Abstract: A housing for a dispensing apparatus. The housing comprising a main housing and a dose dial sleeve. The dose dial sleeve comprising a helical groove configured to engage a threading provided by the housing. A dose knob is disposed near a proximal end of the dose dial sleeve and a piston rod is provided within the housing. The piston rod is non-rotatable during a dose setting step. A driver comprises an internal threading near a distal portion of the driver and is adapted to engage an external thread of the piston rod. A tubular clutch is located adjacent a distal end of the dose knob and operatively coupled to the dose knob. The dose dial sleeve may extend circumferentially around at least a portion of the tubular clutch.
    Type: Application
    Filed: June 4, 2013
    Publication date: October 10, 2013
    Applicant: DCA DESIGN INTERNATIONAL LTD
    Inventors: Robert Frederick Veasey, Robert Perkins, David Aubrey Plumptre
  • Patent number: 8545433
    Abstract: There is provided herein a system, device and methods for performing minimally invasive spider vein treatments. In some embodiments an apparatus for eliminating spider veins comprises a dual syringe mechanism that includes a pusher for pushing sclerosant materials into a target vein, and an extractor for extracting debris from a target vein; a needle for application into a target vein; and a Y-connector connecting each exit of the dual syringe mechanism to the needle. In some implementations the apparatus's dual syringe mechanism includes a locking mechanism to enable controlled advancing of the syringe pusher.
    Type: Grant
    Filed: April 2, 2009
    Date of Patent: October 1, 2013
    Assignee: V.V.T. Med Ltd.
    Inventor: Zeev Brandeis
  • Patent number: 8540681
    Abstract: An injection control device having a metered/controlled injection rate, that is proportional to the rate of withdrawal/injection—suitable for cosmetic as well as other applications—is described. For an injection mode, after the cannula is advanced into an object, the cannula is withdrawn to create a tract or tunnel within the targeted area. As the cannula is withdrawn, filler material in the injection control device is uniformly deposited into the tract or tunnel via the automatic metering system. The automatic metering system incorporates a syringe activating mechanism coupled to a gearing system which is capable of proportioning the deposition (or sucking) rate to the retraction/injection rate of the cannula. Accordingly, more consistent and uniform distribution (or harvesting) of material can be achieved with less cannula passes as well as requiring less dependence on the skills of the practitioner of this device.
    Type: Grant
    Filed: March 4, 2009
    Date of Patent: September 24, 2013
    Assignee: BSECS Holdings, LLC
    Inventor: Hugh E. Hetherington
  • Patent number: 8535277
    Abstract: The present disclosure relates to devices for use in conjunction with a syringe in measuring a dose using the syringe. In certain embodiments, a clip is provided that includes an elongated portion for insertion into a barrel of a syringe and a locking portion that locks onto a feature of the syringe. Once inserted, the clip physically prevents retraction of a plunger of the syringe past a certain point corresponding to a desired dose.
    Type: Grant
    Filed: March 21, 2011
    Date of Patent: September 17, 2013
    Assignee: William Marsh Rice University
    Inventors: Maria Oden, Julia Ellen Davidson Lukomnik, Cindy M. Dinh, Amanda Michelle Guiterrez, Carlos Amaro, Rebecca R. Richards-Kortum
  • Patent number: 8529520
    Abstract: The present invention relates to a medicament delivery device comprising a generally elongated housing comprising a distal and a proximal housing part having opposite distal and proximal ends; a medicament container coaxially arranged within said proximal housing part; drive means (18, 20, 22, 23, 30, 32) arranged to act on said medicament container for expelling a dose of medicament; and an electromechanical dose setting mechanism interactively connected to said drive means; wherein said electromechanical dose setting mechanism comprises a manually operable dose setting button (38); a dose setting member (34) comprising sensors (42) and arranged to be linearly displaced a predetermined distance along a linear path when the dose setting button is manually operated; and a printed circuit board (44) having a code sensing area (46) along the linear path of movement of the sensors, and wherein the sensors are arranged adjacent said code sensing area, such that a value of the immediate position of the dose setting
    Type: Grant
    Filed: August 25, 2009
    Date of Patent: September 10, 2013
    Assignee: SHL Group AB
    Inventor: Mattias Daniel
  • Patent number: 8529513
    Abstract: A device for administering an injectable substance, the device including a housing, a translation member moveable in a translation direction, a rotation member rotatably moveable about a rotation axis and coupled to the translation member to support the translation member counter to the translation direction, a rotary bearing including a bearing body bearing the rotation member rotatably about the rotation axis, the rotary bearing having support surfaces for supporting the rotation member axially on the bearing body, and a device for reducing play whereby at least two support surfaces are brought into contact with a pressing force, thereby reducing an axial play of the rotary bearing.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: September 10, 2013
    Assignee: Roche Diagnostics International AG
    Inventors: Daniel Peter, Simone Gafner-Geiser
  • Publication number: 20130226097
    Abstract: An assembly for a drug delivery device comprises a drive member which is adapted and arranged to be displaced in a dose setting direction for setting a dose of a drug and to be displaced in a dose delivery direction for delivering the set dose of the drug. The assembly comprises a piston rod which is adapted and arranged to be displaced in the dose delivery direction via mechanical interaction with the drive member for delivering the set dose. The assembly comprises at least one resilient pre-delivery element, wherein the assembly is configured such that the resilient pre-delivery element is biased when the drive member is displaced in the dose setting direction for setting the dose, the biased resilient pre-delivery element relaxes before the drive member is displaced in the dose delivery direction for delivering the dose. When the resilient pre-delivery element relaxes, the piston rod is displaced with respect to the resilient pre-delivery element in the dose delivery direction by a pre-delivery distance.
    Type: Application
    Filed: November 11, 2011
    Publication date: August 29, 2013
    Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBH
    Inventors: Steffen Raab, Sandra Arnhold
  • Patent number: 8512296
    Abstract: An injection device (30) features a housing (42, 52) for reception of a container (34) having a fluid (32) to be injected, a first element (94) for ejecting injection fluid (32) from such a container (34), and said first element (94) has an external thread (92). A metering element (66, 88) has an internal thread (90) that is in engagement with the external thread (92) of the first element (94), and said metering element (66) is rotatable, together with the first element (94), for preselection of a desired injection dose. A coupling arrangement (K1) serves, during an injection operation, to create a nonrotatable connection between the first element (94) and the housing (42, 52) and thereby to block, during an injection operation, a rotation of the first element (94) relative to the housing (42, 52) but to enable a rotation of the metering element (66, 88) relative to the housing (42, 52).
    Type: Grant
    Filed: November 5, 2007
    Date of Patent: August 20, 2013
    Assignee: Haselmeier GmbH
    Inventors: Jochen Gabriel, Joachim Keitel