Piston Moved By Screw Or Rack Patents (Class 604/224)
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Patent number: 8926568Abstract: A medicament delivery device includes a housing for a medicament container assembly; a drive member interactively connected to the assembly for expelling a dose of medicament; a dose actuation assembly operably connected to the drive member; and an actuation member interactively connected to the housing and the dose actuation assembly by a gear assembly. The actuation member is movable generally perpendicularly to a longitudinal axis of the device from an initial position, in which the actuation member is positioned within the housing, to a dose-set position, in which a portion of the actuation member protrudes a distance proportional to the set dose from the longitudinal surface of the housing when the dose actuation assembly. The actuation member is manually operated in a direction generally perpendicular to the longitudinal axis of the device from the dose-set position to the initial position for driving the dose actuation assembly and drive member.Type: GrantFiled: May 9, 2011Date of Patent: January 6, 2015Assignee: SHL Group ABInventor: Anders Holmqvist
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Patent number: 8915888Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.Type: GrantFiled: May 15, 2009Date of Patent: December 23, 2014Assignee: Sanofi-Aventis Deutschland GmbHInventors: Malcolm Boyd, Richard Letham, David Plumptre, Robert Veasey, James May, Matthew Jones, Samuel Ghazaros
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Patent number: 8911411Abstract: An injection device with a travelling clutch which can be shifted between two different positions by the activation of an injection button. In the first position, the injection button and the driver is allowed to rotate relatively to the piston rod, which is blocked from rotation by the clicker element. In the second position, the drive sleeve and the injection button is axially movable while the piston rod is allowed to rotate.Type: GrantFiled: June 28, 2010Date of Patent: December 16, 2014Assignee: Novo Nordisk A/SInventor: Lars Ulrik Nielsen
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Patent number: 8858512Abstract: The present invention related to an injector is provided. The injector includes a case body, a dose setting, a first engagement, a second engagement, an elasticity element, and a button. The dose setting is used to preset a dose. The first engagement is connected with the dose setting. The elasticity element is connected between the first engagement and the second engagement. When the elasticity element is in an extension state, the first engagement and the second engagement are separated. When the button is pushed, the elasticity element is entered into a compress state to combine the first engagement and the second engagement, and then push the dose setting.Type: GrantFiled: March 26, 2012Date of Patent: October 14, 2014Assignee: Taidoc Technology CorporationInventors: Yi-Hsin Huang, Chih-Chiang Yang, Chao-Wang Chen
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Publication number: 20140288505Abstract: An assembly for a drug delivery device is provided the assembly comprising a cartridge adapted and arranged to contain at least one dose of a drug, a bung being slidably arranged within the cartridge, a housing comprising a distal end and a proximal end, and a piston rod adapted and arranged for moving the bung in the distal direction with respect to the housing for dispensing a dose of the drug. The assembly further comprises a drive member and arranged for transferring movement to the piston rod for dispensing the dose, and an engagement member configured to mechanically cooperate with the piston rod and with the housing.Type: ApplicationFiled: October 11, 2012Publication date: September 25, 2014Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventor: Michael Harms
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Patent number: 8834158Abstract: A screw syringe having a piston spindle with an external thread, a syringe barrel, having a sleeve with a piston end, and a female part with an internal thread is disclosed. The female part slides onto the piston end. The female part has a flange that creates a form fit with a counter-surface at the piston end so axial displacement of the female part in relation to the syringe barrel in the discharge direction is prevented. The female part has retaining surfaces that create a form fit with counter-retaining surfaces of the piston end, thereby preventing axial displacement of the female part in relation to the syringe barrel counter to the discharge direction. The retaining surfaces and counter-retaining surfaces create a form fit that prevents radial relative movement between the retaining surfaces and the counter-retaining surfaces, directed perpendicularly to the sliding direction.Type: GrantFiled: March 21, 2012Date of Patent: September 16, 2014Assignee: VOCO GmbHInventors: Uwe Leiner, Manfred Thomas Plaumann
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Publication number: 20140257241Abstract: Various handheld medical dispensing configurations and methods including the following: Handheld medical dispensing system comprises a syringe, which has a plunger, releasably mounted to syringe actuation apparatus, the apparatus having an actuator configured such that it can move the plunger more than once to dispense a plurality of amounts of substance from the syringe. A method of dispensing fluid from a syringe comprises holding a medical substance delivery system including a syringe, which has a needle, and which is secured to syringe actuation apparatus configured to dispense predetermined amounts of the substance from the syringe, penetrating the needle at one patient site and using the apparatus to deliver a predetermined amount of the substance, and penetrating the needle at another patient site and using the apparatus to deliver a predetermined amount of the substance.Type: ApplicationFiled: May 23, 2014Publication date: September 11, 2014Applicant: Accunit, LLCInventors: Howard S. SUTKIN, Jerry BOTKIN
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Patent number: 8821440Abstract: An injection device has a dispensing chamber housing, a plunger, and a temperature control device. The dispensing chamber housing has a first part and a second part. The first part is thermally coupled to a needle. The second part is thermally coupled to the first part. The second part has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for holding a quantity of a substance. The plunger is engaged with an inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The temperature control device at least partially surrounds the dispensing chamber housing and is capable of altering a temperature of the substance in the dispensing chamber. The second part has a greater thermal coefficient than the first part.Type: GrantFiled: July 13, 2007Date of Patent: September 2, 2014Assignee: Alcon Research, Ltd.Inventors: Robert Sanchez, James Foster, Cesario Dos Santos
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Patent number: 8702660Abstract: A device for delivering medicament includes a guide nut with guide ledges which cooperate with longitudinal grooves of a plunger rod for providing a rotational lock but allowing longitudinal movement of the plunger rod in relation to the guide nut that is rotationally locked to a distal housing part by engagement devices when the distal housing part and a proximal housing part are connected to each other. The device further includes a pressure release mechanism that includes slanting wedge-like surfaces arranged on the drive nut and slanting wedge-like surfaces arranged on a fixed inner annular surface of the distal housing part, which slanting wedge-like surfaces abut each other such that they move out of contact near the end of delivery of a predetermined quantity of medicament when the drive nut is rotated.Type: GrantFiled: September 7, 2009Date of Patent: April 22, 2014Assignee: SHL Group ABInventor: Martin Karlsson
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Patent number: 8672898Abstract: The present invention relates to a dose setting and expelling device comprising a drive member and a dose setting mechanism which simultaneously sets a given dose and stores the energy necessary for a subsequently driving the drive member in order to expel a dose of medicine from an injection device. According to the invention the dose setting mechanism allows adjustment in both directions, such that a given set dose can be reduced or cancelled by reversing the input motion, typically by rotating a setting member backwardly, this in contrast to the known devices which either requires an additional release mechanism or which cannot be reversed at all.Type: GrantFiled: October 22, 2004Date of Patent: March 18, 2014Assignee: Novo Nordisk A/SInventor: Christian Enggaard
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Patent number: 8652092Abstract: The invention relates to applicators (1) for implantation of an implant, having a cylinder (2) and a plunger (3) displaceably mounted therein, which plunger (3) has a pusher plunger (31) for pushing the implant out of a cannula, the cannula being mounted on a cylinder part, the cylinder part (4) being movably guided in the cylinder (2), there being provided a gear mechanism (5) which couples the plunger (3) to the cylinder part (4), a movement of the plunger (3) relative to the cylinder (2) being converted into an opposite movement of the cylinder part (4).Type: GrantFiled: May 4, 2006Date of Patent: February 18, 2014Assignee: Acino AGInventor: Oliver Bussmann
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Publication number: 20140005610Abstract: A dual chamber prefillable syringe (100) includes: a cylinder (10) which has a bypass portion (11); a hub luer-lock (20); a front stopper (30); a middle stopper (40) which seals a preparation (S) together with the front stopper (30); an end stopper (50) which seals a solvent (L) together with the middle stopper (40); a finger grip (60); and a plunger rod (70) which is connected to the end stopper from the rear end side. A female screw portion (64) which is screwed around the axis line is formed on an inner circumferential surface of the finger grip (60), and a male screw portion (73) which is able to be screwed to the female screw portion is formed on an outer circumferential surface of the plunger rod (70).Type: ApplicationFiled: November 16, 2011Publication date: January 2, 2014Inventor: Harumi Kakiuchi
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Patent number: 8617109Abstract: The present invention relates to a device for the delivery of predetermined doses of liquid medicament to a patient, which medicament is intended to be inhaled by the patient or intended to be injected into the body of the patient. The device is adapted to be in a medicament delivery state and in a medicament non-delivery state. When the device is in a medicament delivery state, said device is adapted to drive a piston into a cartridge containing the liquid medicament to be delivered, with a force that is above or equal to a predetermined minimum force value and below a predetermined maximum force value. The minimum force value is the lowest force value needed to deliver the predetermined dose and the maximum force value is the first force value at which it exists a risk of damaging the cartridge or the components of the device. Further, more of the spring force is brought to an efficient output torque ensuring that a predetermined volume of medicament is expelled from a cartridge.Type: GrantFiled: May 22, 2006Date of Patent: December 31, 2013Assignee: SHL Group ABInventors: Victor Kronestedt, Lennart Brunnberg, Stephan Olson, Tomas Deurell, Anders Karlsson
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Publication number: 20130304021Abstract: Extension rods of a telescoping assembly (TSA) may be assembled in a single direction. The rods may optionally be threaded together from a reverse extended configuration. The rods may optionally resist disattachement during extension. The inner rod may optionally included a leading fastener and/or the outer rod may optionally include a rear fastener. Each rod may optionally be molded as a single piece. End caps may optionally be added to the TSA after extension of the rods. An end cap may optionally include a rotation stopper. In some embodiments the TSA may include a supporting shoulder.Type: ApplicationFiled: April 30, 2013Publication date: November 14, 2013Inventor: MEDIMOP MEDICAL PROJECTS LTD.
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Patent number: 8545442Abstract: An inflation device including a handle mechanism configured to selectively engage and disengage threads within the device. In some instances the threads are configured to couple a plunger to a syringe body. The handle mechanism may be configured to (1) provide a mechanical advantage and (2) change the location and direction of the input force, thereby making the device easier to use.Type: GrantFiled: May 4, 2012Date of Patent: October 1, 2013Assignee: Merit Medical Systems, Inc.Inventors: Fred Lampropoulos, Brian Stevens, William Padilla, Gregory R. McArthur
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Patent number: 8535268Abstract: Devices, systems, and associated methods that facilitate the injection and/or aspiration of precisely controlled volumes of fluids at precisely controlled rates are provided. In some implementations, an apparatus may include a syringe and a lead screw connected to a plunger of the syringe. A ratchet gear may be connected to the lead screw. A mechanism may also be included to oscillate a frame in a direction perpendicular to a longitudinal axis of the lead screw such that one or more pawls of the frame engage the teeth of the ratchet gear in a manner that results in rotation of the ratchet gear in a single direction for controlled linear displacement of the plunger.Type: GrantFiled: December 22, 2010Date of Patent: September 17, 2013Assignee: Alcon Research, Ltd.Inventors: Jack Robert Auld, Brian William McDonell, Barry Lynn Wheatley
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Patent number: 8529513Abstract: A device for administering an injectable substance, the device including a housing, a translation member moveable in a translation direction, a rotation member rotatably moveable about a rotation axis and coupled to the translation member to support the translation member counter to the translation direction, a rotary bearing including a bearing body bearing the rotation member rotatably about the rotation axis, the rotary bearing having support surfaces for supporting the rotation member axially on the bearing body, and a device for reducing play whereby at least two support surfaces are brought into contact with a pressing force, thereby reducing an axial play of the rotary bearing.Type: GrantFiled: March 23, 2006Date of Patent: September 10, 2013Assignee: Roche Diagnostics International AGInventors: Daniel Peter, Simone Gafner-Geiser
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Publication number: 20130211343Abstract: A lead screw, a lead screw nut and a drive member are aligned with an axis defining an axial direction and an opposite axial direction. A coupling between the lead screw and the lead screw nut allows a helical movement of the lead screw with respect to the lead screw nut at least in the axial direction. The lead screw is coupled with the drive member, the coupling generating a helical movement of the lead screw with respect to the drive member when the drive member is moved in the axial direction with respect to the lead screw. A dispense stop feature of the lead screw nut and a dispense stop feature of the drive member prevent the generation of the helical movement of the lead screw when a specified end position of the drive member is approached.Type: ApplicationFiled: October 5, 2011Publication date: August 15, 2013Inventor: David Aubrey Plumptre
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Patent number: 8491538Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.Type: GrantFiled: October 27, 2011Date of Patent: July 23, 2013Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
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Patent number: 8491537Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the cathether are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.Type: GrantFiled: July 9, 2010Date of Patent: July 23, 2013Assignee: Becton, Dickinson and CompanyInventors: Anthony J. Kosinski, Girum Yemane Tekeste, Nichola Charles
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Patent number: 8444607Abstract: A delivery device includes first and second housing portions that selectively engage and disengage. A reservoir on one housing portion operatively engages a drive device and/or a needle inserting device on the other housing portion. Upon proper engagement of the housing portions, the reservoir operatively couples to the drive device and/or the needle inserting device. A first magnet on the first housing portion and a second magnet (or a magnetically-attractive material) on the second housing portion are positioned to magnetically interact with each other, upon operative engagement of the housing portions. A third magnet on the second housing portion may be opposed to the first magnet to help align the housing portions for connection. A magnet-responsive device may be on one or both housing portions to detect alignment and/or connection of the housing portions.Type: GrantFiled: October 8, 2008Date of Patent: May 21, 2013Assignee: Medtronic MiniMed, Inc.Inventors: R. Paul Mounce, Melissa D. Norton, Robert M. Guezuraga, Bradley J. Enegren, Paul F. Bente, IV, Ian B. Hanson, Julian D. Kavazov, Christopher G. Griffin, Sheldon B. Moberg, Mark D. Holt, Susie E. Maule, Paul H. Kovelman
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Publication number: 20130110054Abstract: A drive assembly for a drug delivery device, comprising a housing with a proximal end and a distal end, and a longitudinal axis (A) extending between the proximal end and the distal end, a rotation sleeve being rotatable relative to the housing, and a piston rod being axially moveable relative to the housing. The piston rod is in mechanical cooperation with the rotation sleeve to be rotatable and moveable in the distal direction relative to the housing when the rotation sleeve rotates in a first direction (D1) and to be stationary in axial direction relative to the housing when the rotation sleeve rotates in a second direction (D2) opposite to the first direction (D1).Type: ApplicationFiled: December 6, 2010Publication date: May 2, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Steffen Raab, Uwe Dasbach
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Patent number: 8394070Abstract: A device for administering a liquid preparation comprising a pharmaceutical agent, particularly a contrast agent, in the form of a bolus. The device comprises in particular a core cylinder and an external cylinder, the core cylinder comprising a conduit (107) and a cylindrical reservoir (108) cooperating with a respective plunger (109), wherein the plunger is modified in order to operatively engage with guiding means (300) provided on the external cylinder.Type: GrantFiled: December 15, 2009Date of Patent: March 12, 2013Assignee: Bracco Suisse S.A.Inventors: Laurent Jakob, Frederic Rivas
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Publication number: 20130030382Abstract: A plunger kit for a medicine syringe provided with a syringe barrel includes a piston having an internal screw and a plunger rod having an external screw. The internal screw and external screw have a mutually non-complementary, basic groove profile and basic thread profile, respectively. A following flank of each thread of the external screw and a groove flank of a corresponding groove of the internal screw are formed such that, when the piston and plunger rod are slidably fit in the syringe barrel and the piston is then slid in a pull direction, the following flank can come into contact with the groove flank more strongly at a first part and more weakly at a second part to increase thread engagement strength between the external screw and the internal screw without any substantial expansion of the piston by the external screw.Type: ApplicationFiled: July 24, 2012Publication date: January 31, 2013Applicant: DAIKYO SEIKO, LTD.Inventor: Nobuo SUDO
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Publication number: 20130030381Abstract: The drive assembly comprises a guide nut (4), a locking means (9), and a fastener (14), the fastener being movable with respect to the locking means into and out of a position, in which the fastener engages the locking means with the guide nut.Type: ApplicationFiled: January 24, 2011Publication date: January 31, 2013Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Christopher Langley, Christopher Jones, Paul Draper
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Patent number: 8353892Abstract: Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes.Type: GrantFiled: May 4, 2011Date of Patent: January 15, 2013Assignee: Medtronic Vascular, Inc.Inventors: Dustin Thompson, Patrick Macaulay
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Patent number: 8333739Abstract: A medication dispensing device with a housing and a member wherein the member is moveable in a distal direction is useful in delivering medication to a patient. A fluid container can be used with the device and often has a moveable piston at one end and an outlet at the other. The member receives a force from a user and drives the piston in the distal direction to expel medication. A intermediate system is disposed between the member and the piston including a gear set that has a pinion in meshed engagement with a rack. The system allows the member to move a greater distance than the piston moves thereby increasing the force on the piston.Type: GrantFiled: October 31, 2007Date of Patent: December 18, 2012Assignee: Novo Nordisk A/SInventor: Claus Schmidt Møller
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Patent number: 8316898Abstract: Automatic liquid drug preparation apparatus for preparing a liquid drug assemblage with a predetermined dosage of liquid drug. The liquid drug assemblage is prepared from a preparatory assemblage including a fluid control device having a body member with a syringe port, a vial adapter, and an administration port, a vial pre-filled with powder or liquid medicament, and a syringe pre-filled with diluent for mixing with the medicament. The automatic liquid drug preparation apparatus includes a housing, a cradle for receiving the preparatory assemblage, and a controller for controlling a motorized syringe drive unit for selectively transferring liquid contents between the syringe and the vial, a motorized cradle drive unit for selectively rotating the cradle relative to the housing, and a motorized vial adapter release unit for selectively detaching the vial adapter with its attached spent vial from the body member to form the liquid drug assemblage.Type: GrantFiled: May 4, 2008Date of Patent: November 27, 2012Assignee: Medimop Medical Projects Ltd.Inventors: Freddy Zinger, Igor Denenburg, Amir Lev
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Publication number: 20120296286Abstract: A piston rod is arranged in a body and provided with a helical element and an axial element. A guide element, which is arranged in the body and fixed relatively to the body, is coupled to the helical element to guide a helical movement of the piston rod and coupled to the axial element to guide an axial movement of the piston rod. The axial movement allows a priming of the device preceding the helical movement of the piston rod.Type: ApplicationFiled: September 3, 2010Publication date: November 22, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Steffen Raab, Sandra Arnhold
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Publication number: 20120289929Abstract: The present invention relates to drive mechanisms suitable for use in drug delivery devices, in particular pen-type injectors, wherein a number of pre-set doses of medicinal product can be administered. In particular, the present invention relates to such drug delivery devices where a user may activate the drug delivery device.Type: ApplicationFiled: January 10, 2012Publication date: November 15, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Malcolm Boyd, Richard Letham, David Plumptre, Robert Veasey, James May, Matthew Jones, Samuel Ghazaros
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Patent number: 8308726Abstract: A system to minimize fluid turbulence inside a tissue cavity during endoscopic procedures. A body tissue cavity of a subject is distended by continuous flow irrigation using a solenoid operated pump on the inflow side and a positive displacement pump, such as a peristaltic pump, on the outflow side, such that the amplitude of the pressure pulsations created by the outflow positive displacement pump inside the said tissue cavity is substantially dampened to almost negligible levels. The present invention also provides a method for accurately determining the rate of fluid loss into the subject's body system during any endoscopic procedure without utilizing any deficit weight or fluid volume calculation, the same being accomplished by using two fluid flow rate sensors. The present invention also provides a system of creating and maintaining any desired pressure in a body tissue cavity for any desired cavity outflow rate.Type: GrantFiled: September 1, 2005Date of Patent: November 13, 2012Inventors: Atul Kumar, Alka Kumar
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Publication number: 20120283661Abstract: A drive mechanism for a drug delivery device, preferably for a pen-type injector, the mechanism comprises a spindle (6) movable in a first direction during a delivery step, a splined portion (5, 11) operatively coupled to the spindle (6), and retraction means (12, 15, 16, 17, 20) acting on the splined portion (5, 11) at least at the end of the delivery step. Thereby, that after the delivery step the spindle (6) and/or the splined portion (5, 11) is moved in a second direction contrary to the first direction, such that the whole drive mechanism is relieved from stresses.Type: ApplicationFiled: September 3, 2010Publication date: November 8, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Jugl, Gunther Sendatzki, Axel Teucher
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Patent number: 8298194Abstract: A refillable injection device (1) having a dose setting mechanism with a dose setting member (4) and a dose rod (11). The dose setting member and the dose rod engage during normal operation of the injection device, and they do not engage during change of cartridge. The dose setting member and the dose rod need to be moved into engagement when a new cartridge is inserted in the injection device. Thereby there is a risk that stress is build-up in the piston rod. In order to prevent this, the cartridge holder is operatively connected to the dose rod in such a manner that when a cartridge is being inserted in the cartridge holder, the dose rod is caused to move along with the piston rod in an axial direction, at least while the dose setting member and the dose rod are moved into engagement.Type: GrantFiled: February 23, 2007Date of Patent: October 30, 2012Assignee: Novo Nordisk A/SInventor: Claus Schmidt Møller
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Publication number: 20120265153Abstract: The present invention relates to a housing component of a drug delivery device (10) to accommodate a drive mechanism (11), wherein the drive mechanism (11) is operable to interact with a piston (20) of a cartridge(16) containing a medicinal product to be dispensed by the drug delivery device. The housing component comprises at least one radially inwardly extending flange portion (16) to be operably engaged with a piston rod (24) of the drive mechanism (11), characterized in that the flange portion (16) is at least partially structurally strengthened.Type: ApplicationFiled: August 26, 2010Publication date: October 18, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Jugl, Gunther Sendatzki, Axel Teucher, Axel Forstreuter
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Publication number: 20120253293Abstract: The present invention related to an injector is provided. The injector includes a case body, a dose setting, a first engagement, a second engagement, an elasticity element, and a button. The dose setting is used to preset a dose. The first engagement is connected with the dose setting. The elasticity element is connected between the first engagement and the second engagement. When the elasticity element is in an extension state, the first engagement and the second engagement are separated. When the button is pushed, the elasticity element is entered into a compress state to combine the first engagement and the second engagement, and then push the dose setting.Type: ApplicationFiled: March 26, 2012Publication date: October 4, 2012Inventors: Yi-Hsin Huang, Chih-Chiang Yang, Chao-Wang Chen
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Publication number: 20120209248Abstract: Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented.Type: ApplicationFiled: February 10, 2012Publication date: August 16, 2012Applicant: Tau Tona Group Research and Development Company, L.L.C.Inventors: Geoffrey C. GURTNER, Michael H. ROSENTHAL, Brian J. DOMECUS, Darin GITTINGS, Kinman HONG
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Publication number: 20120109075Abstract: The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device.Type: ApplicationFiled: March 31, 2010Publication date: May 3, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Harms, Steffen Raab, Udo Stauder
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Publication number: 20120101451Abstract: A manually actuated pump, such as a bolus delivery circuit of an insulin pump, combines a direct drive piston system with a lost motion valve system, to deliver reliably a full bolus dose, while precluding partial dosing or inadvertent overdosing conditions. The pump may also include a signaling device to indicate when a full bolus dose is delivered.Type: ApplicationFiled: October 22, 2010Publication date: April 26, 2012Inventors: Christopher S. Boit, Peter Gravesen, Heiko Arndt, Gregory H. Peatfield, Patrick F. McDermott
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Publication number: 20120101452Abstract: A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated.Type: ApplicationFiled: March 31, 2010Publication date: April 26, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Harms, Volker Korger, Uwe Dasbach, Steffen Raab
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Publication number: 20120083748Abstract: A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset.Type: ApplicationFiled: March 31, 2010Publication date: April 5, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Michael Harms, Volker Korger, Uwe Dasbach, Steffen Raab
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Patent number: 8075534Abstract: A drive and dosing module for an injection device, and an injection device including the module, wherein the module includes a dosing member which can be displaced into one of several dosing positions in relation to a drive member to set a product dose, wherein one of the dosing or drive members forms several dosing stops at axially different heights and rotational stops that are associated with the dosing stops and the other member forms at least one selection element, and wherein the drive member can be moved in relation to the dosing member until it reaches a trigger position in which the at least one selection element attains one of the dosing stops and, in said trigger position, the selection element and the rotational stops combine to lock the rotation of the dosing member in both directions.Type: GrantFiled: July 20, 2010Date of Patent: December 13, 2011Assignee: TecPharma Licensing AGInventors: Stefan Burren, Ulrich Moser, Christian Schrul, Christoph Sommer
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Patent number: 8062268Abstract: The present invention relates to an injector comprising a housing (10); a medicament container (12) disposed within the housing, wherein the container has at least one chamber, a front opening with or for an injection needle for delivering the medicament therethrough, and at least one movable stopper; a drive unit (22) slidable arranged within the housing, and capable of acting on said container for expelling medicament through said needle; and a scroll wheel member (24) operatively connected to said housing via a transmission and wherein said scroll wheel member comprises friction enhancing means such that it is capable of being maneuverable with a finger of a user for performing a function.Type: GrantFiled: December 4, 2008Date of Patent: November 22, 2011Assignee: SHL Group ABInventor: Jochen Ratjen
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Patent number: 8052654Abstract: A syringe (10) has a plunger (20), a barrel (11) and a collar (40, 50) with two pawls (42A, 42B). The plunger has two opposed ratchets (23A, 23B) that align with the one each of the pawls and thereby or impede, withdrawal of the plunger during or following depression of the plunger. The barrel has a collar with an inner (50) and an outer member (40) that are incapable of rotation relative with respect to each other. The outer member has the two pawls (42A, 42B) and two fingers that slidably engage opposed guide slots (28) on the plunger to thereby prevent or minimize rotation of the plunger relative to the collar. The inner member of the collar is operable to prevent engagement of the plunger ratchet by the two pawls until the plunger is depressed.Type: GrantFiled: January 28, 2005Date of Patent: November 8, 2011Assignee: Unitract Syringe Pty Ltd.Inventors: Joseph Hermes Kaal, Craig Stephen Thorley, Damien Judd
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Patent number: 8048037Abstract: An injection device including a drive unit, a delivery unit, a dosing unit, a trigger for triggering an injection, a first coupling mechanism between the drive unit and the delivery unit, and a second coupling mechanism between the dosing unit and the drive unit, wherein the drive unit is tensioned by a rotation of the dosing unit and when the drive unit is tensioned the first coupling mechanism is disengaged and the second coupling mechanism is engaged, and wherein when an injection is triggered first the first coupling mechanism is engaged and then the second coupling mechanism is disengaged. In some embodiments, the device may include a third coupling mechanism which only releases the delivery unit after the engagement and disengagement which follow a triggering.Type: GrantFiled: March 13, 2009Date of Patent: November 1, 2011Assignee: TecPharma Licensing AGInventors: Philippe Kohlbrenner, Peter Stettler, Patrick Hostettler, Juergen Wittmann, Martin Wittwer
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Patent number: 8012131Abstract: An injection device for dispensing a dose of a substance, the device including a housing, a dispensing element which can be displaced relative to the housing and a locking element which can be coupled with the dispensing element during or after a substance dispensing operation so that after the dispensing element has effected a dispensing operation once, it can no longer be operated to dispense another dose, and a method of locking an injection device after a substance has been dispensed once, whereby a dispensing element operated to dispense the substance is locked or blocked before, during or after dispensing a set dose so that no more substance can be dispensed.Type: GrantFiled: January 16, 2007Date of Patent: September 6, 2011Assignee: TecPharma Licensing AGInventors: Ulrich Moser, Christian Schrul, Juerg Hirschel
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Patent number: 8007476Abstract: An administering apparatus having a casing including a reservoir for a product to be administered, a piston which can be shifted in the reservoir in an advancing direction towards a reservoir outlet to administer the product, a piston rod, a dosing and drive element for performing a dosing movement for selecting a product dose and a delivery movement for delivering the product dose, and a dose setting member which is moved in the advancing direction during the delivery movement, and which engages the piston rod and the casing such that it can only be moved in the advancing direction jointly with the piston rod and is moved counter to the advancing direction relative to the piston rod during the dosing movement.Type: GrantFiled: January 29, 2004Date of Patent: August 30, 2011Assignee: TecPharma Licensing AGInventors: Roney Graf, Fritz Kirchhofer
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Patent number: 7967795Abstract: A cartridge interface assembly including a driving plunger including an outer shaft, and a driver including an inner shaft, the inner shaft mating with an intermediate shaft, the intermediate shaft mating with the outer shaft, so that the shafts are movable telescopically with respect to one another, wherein rotation of the driver causes the driving plunger to advance in a direction away from the driver.Type: GrantFiled: January 19, 2010Date of Patent: June 28, 2011Assignee: LaModel Ltd.Inventor: Oz Cabiri
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Patent number: 7959612Abstract: Devices and methods for simultaneous injection or delivery of two or more substances from separate syringes. The syringes are loaded into a device that has a handle and a screw driven mechanism for simultaneously depressing the plungers of the syringes. The user grasps the handle and positions the device. Thereafter, the screw mechanism is used to simultaneously advance the plungers of the syringes thereby simultaneously expelling the substances from the syringes.Type: GrantFiled: April 21, 2008Date of Patent: June 14, 2011Assignee: Medtronic Vascular, Inc.Inventors: Dustin Thompson, Patrick Macaulay
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Patent number: 7896850Abstract: The present invention relates to a device for the delivery of predetermined doses of liquid medicament to a patient, which medicament is intended to be inhaled by the patient or intended to be injected into the body of the patient. The device is adapted to be in a medicament delivery state and in a medicament non-delivery state. When the device is in a medicament delivery state, said device is adapted to drive a piston into a cartridge containing the liquid medicament to be delivered, with a predetermined force value. The device is designed and arranged to ensure that the predetermined dose of medicament expelled from the cartridge has a high degree of accuracy and to show the user in a simple manner how much medicament is remaining in the cartridge after a dose or several doses has/have been expelled and at the same time offering a shorter device, which is more convenient for the user when he/she has to carry it with him/her.Type: GrantFiled: May 22, 2006Date of Patent: March 1, 2011Assignee: Telefonaktiebolaget L M Ericsson (publ)Inventors: Victor Kronestedt, Lennart Brunnberg, Stephan Olson
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Patent number: 7857791Abstract: A medication dispensing apparatus having a gear set (62) to provide a mechanical advantage to the plunging of the apparatus plunger (64). The gear set has a first pinion (114) in meshed engagement with a rack (91) of the plunger, and a second pinion (126) in meshed engagement with a rack (80) of a drive member (68) of the apparatus. The gear set operatively interconnects the plunger and the drive member such that after the plunger is moved relative to the housing (30, 31) in proximal direction to prepare the apparatus for injection, the plunger, when distally moved, causes the drive member to advance in a distal direction to force medication through an outlet, typically provided with an injection needle (40), at the distal end (22) of the apparatus. An opening (130) through one of the pinions accommodates the drive member to allow for a compact apparatus.Type: GrantFiled: March 25, 2005Date of Patent: December 28, 2010Assignee: Eli Lilly and CompanyInventors: Alexander Thomas Jacobs, Jared Alden Judson