Abstract: Syringe assemblies comprising a disinfecting reservoir collar to ensure adherence to aseptic techniques for use in flush procedures for vascular access devices (VAD's) are described. The syringe assemblies include a plunger rod, a syringe barrel, and reservoir collar that permits disinfection of a hub of a VAD connector upon connection to the reservoir collar. Also described are methods of disinfecting vascular access devices.

Abstract: The invention faces the technical problem of reducing the manufacturing costs of medical devices while at the same time a secure, quick and easy reception of a needle by said medical device is guaranteed. The technical problem is solved by a needle guide configured to receive a needle in a first opening in an axial direction of the needle guide, comprising a guide area comprising the first opening and a second opening, a flange area and a connection area, wherein said connection area is configured to non-detachably connect said needle guide to a medical device and wherein said needle guide is made of metal. The technical problem is further solved by a method to produce a needle guide, wherein said needle guide comprises a guide area, a flange area and a connection area, comprising the steps of deep drawing a metal sheet to produce the guide area.

Abstract: An accessory for a syringe is disclosed, including a body with a proximal end having at least one zone for application of an injection force in order to apply a force for discharging a product from the syringe, and a distal end having a bearing element for bearing against a needle mounted on the mouth of the syringe with a force that includes a radial component perpendicular to the longitudinal axis of the syringe and directed towards the centre of the syringe. An assembly including such an accessory and a syringe is also disclosed.

Abstract: Systems and methods for administering drugs to a patient, including a syringe system. The syringe system includes a plastic needle coupled to an end of a syringe barrel, the needle including a proximal taper and a distal taper. A cannula assembly is removably coupled to the plastic needle, the cannula including mating surfaces for the proximal and distal tapers of the plastic needle. The syringe system can also include a cannula cover with a first and second end with different sizes to respectively attach to the cannula assembly and the barrel when the cannula assembly is removed. The cannula may have a distal tip cut at an angle to ensure maximum removal of drug from a given vial.

Abstract: A prefilled syringe for injecting medicament into a patient includes a barrel constructed of a polymeric material, a cannula and a hub. The barrel has a diameter, a longitudinal axis, a proximal end and a distal end. The cannula has a proximal end and a tip opposite the proximal end. The proximal end of the cannula is fixed to the distal end of the barrel. The cannula is positioned generally coaxially with the longitudinal axis. The hub is integrally formed with the distal end. The hub includes a rib section and a cap. The rib section has a generally cruciform cross-section taken along a rib plane. The rib plane is generally perpendicular to the longitudinal axis. The cap has a generally U-shaped cross-section taken along a longitudinal plane. The longitudinal plane is generally parallel to the longitudinal axis.

Abstract: A one-time use device to deliver preservative-free follicle stimulating hormone (FSH) solution is disclosed. The device includes a needle covered by a sliding needle shield, which covers the needle in all modes of the device. The device can be placed into a ready-to-use position in four or fewer user steps. The device has a knob for setting a desired dose of FSH. The knob includes longitudinally spaced elements respectively corresponding to the lock position and the seven or fewer discrete dosing positions. The device locks after one use and cannot be reused thereafter.

Abstract: A prefilled syringe for injecting medicament into a patient includes a barrel constructed of a polymeric material, a cannula and a hub. The barrel has a diameter, a longitudinal axis, a proximal end and a distal end. The cannula has a proximal end and a tip opposite the proximal end. The proximal end of the cannula is fixed to the distal end of the barrel. The cannula is positioned generally coaxially with the longitudinal axis. The hub is integrally formed with the distal end. The hub includes a rib section and a cap. The rib section has a generally cruciform cross-section taken along a rib plane. The rib plane is generally perpendicular to the longitudinal axis. The cap has a generally U-shaped cross-section taken along a longitudinal plane. The longitudinal plane is generally parallel to the longitudinal axis.

Abstract: The present invention relates to a method of producing syringes. Said method comprises fixing a needle to a syringe body by use of an adhesive followed by subjecting the syringes thus obtained to heat treatment. The invention further relates to a method of reducing leachables and/or extractables in prefilled syringes, said method comprising heat treating pre-fabricated syringes at a temperature of at least 40° C. before filling.

Abstract: A syringe comprising a first coding feature for mechanical interaction with a second coding feature of an auto-injector device is provided. The first coding feature is designed such that the syringe is only mountable in an auto-injector device having a second coding feature mating the first coding feature. Furthermore, an auto-injector device having a housing, wherein a syringe can be mounted, and a set of at least two auto-injector devices and syringes are provided.

Abstract: An injection needle assembly is presented having a tubular needle holder with distal and proximal engagement means, a tubular cap having proximal inner and outer engagement means, a tubular needle cover having a first engagement means arranged to cooperate with the proximal engagement means, and second engagement means arranged to cooperate with the proximal outer engagement means of the cap. The needle cover is arranged to be displaced from a first position wherein the second engagement means and the proximal outer engagement means prevents the needle cover and the needle holder to be axially displaced by a linear displacement, to a second position wherein the needle cover and the needle holder are distally displaced. The proximal inner engagement means of the cap and the distal engagement means of the needle holder prevents the needle holder to be proximally displaced but allows the needle cover to be distally displaced.

Abstract: Disclosed in certain embodiments is a pressure sensing tube for transporting a material under pressure through a lumen and a pressure sensitive material associated with the tube and operable to change in appearance in response to a physical change in the tube caused by pressure within the lumen. A method of manufacturing a pressure sensing tube is also disclosed.

Abstract: The present invention inter-alia relates to an apparatus comprising a needle guide configured to at last partially receive a needle of a needle assembly in a longitudinal opening and to center the needle of the needle assembly in the longitudinal opening, wherein the needle guide is longitudinally compressible.

Abstract: A medicament delivery device comprises a housing having a longitudinal axis, a medicament delivery mechanism within the housing, a dispense interface disengagement actuator and a detachable dispense interface. The interface is moveable between a first operative position in which the dispense interface is securely engaged and at least partially contained within the housing, and a second non-operative position in which the dispense interface is partially engaged and at least partially extending from the housing such that it can be detached from the housing manually. The travel of the dispense interface from the first position to the second position is along the longitudinal axis in a direction away from the housing and the movement from the first to the second position is actuated by the dispense interface disengagement actuator.

Abstract: A pen needle hub and cover for a pen needle assembly that provides tactile and/or audible indicia of proper attachment between the hub of the pen needle and the pen is provided. Such indicia substantially prevent under- and over-torquing of the pen needle. The tactile indicia may include a user sensing a wave of a torque of peak value followed by a torque of lesser value.

Abstract: The invention is related to an apparatus comprising: a valve body comprising two inlet openings, one outlet opening and a central space connecting the inlet openings and the outlet opening, and a spherical element movably contained inside the central space configured for translatory movement and configured to seal either the first inlet opening or the second inlet opening, wherein each of the inlet openings are configured for fluid communication with a first reservoir and with a second reservoir and wherein the outlet opening is configured for fluid connection with a septum. This apparatus solves the object to make the exchange of used parts including the valve construction less complex. A further object of the invention is to make the exchange easier to handle. The invention is also related to a medical device comprising a dispense interface and an apparatus of the afore-mentioned type.

Abstract: The invention is related to an apparatus comprising a needle hub comprising at least one channel configured to guide a liquid, especially a liquid drug component, a needle comprising a cannula configured to guide the liquid and a plate fixedly connected to one end of the cannula, wherein the plate is configured to interact with the needle hub for fixing the needle to the needle hub. The invention further is related to an apparatus comprising a cannula configured to guide a liquid, especially a liquid drug component, and a plate fixedly connected to one end of the cannula.

Abstract: A medical device for use with a fluid transfer device includes a hub having an open proximal end with a frusto-conically-shaped cavity therein, a distal end and a passageway therethrough. The cavity is part of the passageway. A release element in the passageway of the hub is positioned to block fluid-tight engagement of the frusto-conically-shaped tip with the cavity of the hub. Structure is provided to release at least part of the release element, upon application of a proximally directed force on the hub, to allow the abrupt fluid-tight engagement of the tip and the cavity in the hub.

Abstract: A needle tube having a needle tip for puncturing skin; a needle hub; and a fluid-draining portion for enabling draining of a medicine. The needle hub includes: a retention part (first member) for retaining the needle tube; an insertion part into which the output portion of a syringe is inserted; and a flange-like skin contact portion that is disposed in a manner so as to cover an area surrounding the needle tube and makes contact with and/or faces the skin when a living body is punctured with the needle tube. The fluid-draining portion is disposed in the skin contact portion of the needle hub and enables a user to drain the medicine that has spilled when removing air and is held in the skin contact portion.

Abstract: The invention faces the technical problem of providing a tight connection between a tube and an dispense interface, while at the same time the biocompatibility of the connection can be improved. The technical problem is solved by an apparatus comprising a tube configured to guide a medium and a dispense interface. The tube comprises a first opening and a second opening, while the dispense interface comprises a recess. The recess has a first opening and a second opening and the tube is at least in part inserted into the recess. The tube is permanently affixed to the dispense interface by a combination of an interference fit and an adhesive, such that the interference fit prevents the adhesive from contaminating the medium.

Abstract: A needle tube having a needle tip for puncturing skin; a needle hub; and an absorption part for absorbing a medicine. The needle hub includes: a retention part (first member) for retaining the needle tube; an insertion part into which the output portion of a syringe is inserted; and a flange-like skin contact portion that is disposed so as to cover an area surrounding the needle tube and that makes contacts with and/or faces the skin when a living body is punctured with the needle tube. The absorption part is disposed in the skin contact portion of the needle hub and absorbs medicine that has been spilled during air removal and is held in the skin contact portion so as to thereby prevent the medicine from attaching to or contacting the skin of a user.

Abstract: Described is a needle assembly comprising of a needle hub having a coupling mechanism adapted to engage corresponding coupling mechanism of a retainer, and a notch formed in a proximal end of the needle hub, wherein the notch is adapted to engage a projection on the retainer.

Abstract: An injection needle assembly includes a needle having a needle point to puncture skin, a needle hub including a first member which holds the needle, and a second member in which a discharge part of a syringe is to be fitted, and an elastic member disposed inside the second member to make liquid-tight close contact with the inner surface of the second member, with the elastic member having an insertion hole in which the needle tube is inserted.

Abstract: A pen needle assembly is provided herein which includes: a hub having a body with a transverse wall; an arrangement for mounting the hub onto an injector; a first needle cannula extending distally from the transverse wall, the first needle cannula terminating at a distal end, formed for insertion into a patient, with a first lumen extending proximally from the distal end, the first needle cannula being of a first gauge; and, a second needle cannula extending proximally from the transverse wall, the second needle cannula extending from a distal end and terminating at a proximal end with a second lumen extending distally from the proximal end. The first and second lumens are in communication. Further, the second needle cannula is of a second gauge, the second gauge defining a larger external cross-section than the first gauge.

Abstract: A cartridge assembly apparatus for an auto-injector includes a flexible container containing a liquid medicant. A needle hub is connected to the flexible container. A needle is attached to the needle hub and extends proximally from the needle hub. A frame is connected to the needle hub and includes a frame proximal end extending proximally beyond a proximal end of the needle. The needle hub and the needle are displaceable relative to the frame in a proximal direction to insert the needle into a patient.

Abstract: A medical device for use with a fluid transfer device includes a hub having an open proximal end with a frusto-conically-shaped cavity therein, a distal end and a passageway therethrough. The cavity is part of the passageway. A release element in the passageway of the hub is positioned to block fluid-tight engagement of the frusto-conically-shaped tip with the cavity of the hub. Structure is provided to release at least part of the release element, upon application of a proximally directed force on the hub, to allow the abrupt fluid-tight engagement of the tip and the cavity in the hub.

Abstract: A medical instrument with attached needle includes a needle tube having a needle tip capable of piercing a living body and a needle holding member for fixing and holding a middle portion of the needle tube by high frequency welding so that the needle tip protrudes from one end and a proximal portion of the needle tube protrudes from the other end. It also has a seal member composed of an elastic member and provided on an outer circumference of the proximal portion of the needle tube so as to be liquid-tight, and a liquid containing member having a liquid chamber capable of containing a liquid therein. With the proximal portion of the needle tube communicating with the liquid chamber, the seal member is compressed by and clamped between the needle holding member and the liquid containing member.

Abstract: A needle mounting system and methods for mounting a needle assembly on a needle mount are disclosed. The needle mounting system includes a needle hub having protrusions extending radially inward. A needle mount has a plurality of slots to receive the protrusions. The slots have a first portion that defines a passageway substantially parallel to a longitudinal axis of the needle mount and a second portion substantially perpendicular to the axis. The needle hub and mount provide a method wherein a needle assembly may be mounted on an injection device without completely rotating the needle hub relative to the needle mount.

Abstract: Embodiments of the present invention provide a syringe with a needle and method of forming thereof. The syringe with the needle includes a needle tube having a needle tip to puncture a living body and a syringe. The syringe further includes a main body filled with a drug, a fixing section for fixing the needle tube in a state where the needle tip of the needle tube being protruded, and a connecting section at which the fixing section and the main body are connected. The connecting section is provided with a holding hole into which a proximal portion of the needle tube is inserted. The needle tube and the fixing section are fixed by forming at least a portion of the fixing section from a resin composed of essentially the same material as the syringe, after the proximal portion of the needle tube has been inserted into the holding hole.

Abstract: A syringe is provided with a needle that includes a needle tube having a needle tip that can puncture a living body, a needle holding member, and an outer tube that is filled with a drug. The needle holding member is formed integrally and coaxially with the needle tube by insert molding. The needle holding member has a distal end and a proximal end, and can hold the needle tube in a state where the needle tip of the needle tube is protruded from the distal end. The outer tube is fixed to the needle holding member by welding. The needle holding member and the outer tube are formed from essentially the same material.

Abstract: An automatic medicament injector having a compartment for a dry medicament component and a compartment for a wet medicament component. The two compartments are separated by a seal structure that converts from a sealing condition to a mixing condition when the device is activated. The seal structure includes a wiper that scrapes the interior walls in the dry component compartment to prevent the dry component from accumulating at the seal/glass interface. A tapered insert funnels the mixed medicament components to an attached needle assembly, but can be removed when the device is filled. A filter is provided between the medicament compartments and the needle assembly. A chamber between the filter and the needle allows for better flow through the filter. An actuation assembly drives the seal structure into the mixing condition and forces the mixed medicament through the needle and into the user.

Abstract: A safety syringe with retractile rotation is disclosed. The plunger is capable of rapidly embedding with and positioning at the needle set, the next step of the retractile movement to retract the needle is easily processed by a user, and the needle set is firmly assembled and positioned at the open end of the barrel so as to not easily result an unpredictable phenomenon, such as deteriorating the suitability between the needle set and the barrel to result the needle set indentation and leakage when injecting from a sharp raise in temperatures, or overtightening the needle set and the barrel to result the needle and the needle set incapable of retracting in the barrel from the sharp fall of temperature. Furthermore, this invention is capable of achieving one hand operation with safety, improving environmental protection quantity, and easy use for retracting the needle.

Abstract: The present invention relates A needle assembly for a drug delivery device comprising: a cup-shaped receptacle of non-circular cross section having a bottom section supporting a needle element being adapted to penetrate a pierceable seal of a cartridge to be disposed in a cartridge holder of the drug delivery device, wherein the receptacle comprises fastening means adapted to engage with fastening means of a support section of the cartridge holder for releasably fastening the needle assembly, wherein the fastening means are convertible into a release configuration by changing the radial distance of mutually corresponding fastening means through twisting the receptacle with respect to the support section.

Abstract: Disclosed herein is a syringe comprising a syringe body with plunger and a multi-pronged actuator. The syringe can further include a male coupling member, an outer sheath, a valve member and a back plate.

Abstract: Systems and methods involving transferrable identification tags are provided. In one embodiment, a system includes a delivery device, a container, and a tag coupled to the container and configured to store information related to contents of the container. The delivery device is engageable with the tag and at least a portion of the contents of the container are transferrable from the container to the delivery device following its engagement with the tag. The tag is removable from the container in engagement with the delivery device such that the delivery device carries the tag following its removal. In one form, a frangible member is coupled to and extends between the tag and the container, and the tag is removable from the container by the delivery device upon breakage of the frangible member. Other embodiments include unique methods, systems, kits, assemblies, equipment, and/or apparatus which involve transferrable identification tags.

Abstract: A sprayer which inhibits or prevents clogging from occurring in a nozzle when a liquid is ejected from the nozzle includes a nozzle having a first internal tube through which a first liquid passes, and a second internal tube through which a second liquid passes. An external tube is provided in which the first internal tube and the second internal tube are positioned so that the gas passes therebetween. In the sprayer, each distal end part of the first internal tube and the second internal tube includes a gas permeable film impermeable to each liquid, and permeable to the gas.

Abstract: A dedicated needle assembly (300) that can be attached only to a dedicated drug delivery device (400) is disclosed. The dedicated needle assembly (300) comprises a connecting body (320) extending from a distal end to a proximal end. A dedicated mechanical coupling (310) is configured at the proximal end of the connecting body (320). The dedicated mechanical coupling (310) forms a releasable connection to a distal end of the dedicated drug delivery device (400). The dedicated needle assembly (300) may comprise a medicated module or, alternatively, a non-medicated module. In one arrangement, the dedicated mechanical coupling (310) is integral with the dedicated needle assembly (300).

Abstract: A dispenser device comprising a pistol housing, a needle direction control mechanism, a boost mechanism, a quantification control mechanism, and a combination of the pistol housing, the needle direction control mechanism, the boost mechanism, and a syringe positioning mechanism or a holding ring embodies the present invention with features and advantages shown as follows, (1) Uniform injection of agents synchronously mixed by not less than two contents; (2) Mixed agents not exposed in air; (3) Uniform injection, high air tightness, injection direction controlled by easy turning, smooth and convenient operation, high powerful operation via shifts of a push rod driven by a pressed trigger, promoted yield rate, assembly easily constructed, reduced manufacture cost, and convenient maintenance.

Abstract: An attachment for a parenteral device, the device comprising a body and an outlet for conveying fluid, the attachment comprises a housing (12) adapted for engagement with the body, an elongate hollow needle (30), having an outer end (32) and an inner end (34), with an aperture at both ends, a carrier (40) for carrying the needle, the carrier being movable relative to the housing from a first, position, at which the outer end is received within the housing, to a second position at which the outer end extends from the housing and the carrier being movable from second position to first position, and the housing having a flow path extending, when the carrier is in second position, between the outlet and the carrier, wherein the needle is open at the inner end; whereby when the carrier is positioned in second position the inner end is brought into communication with the flow path.

Abstract: The present invention relates to a needle assembly for a drug delivery device comprising of a cup-shaped receptacle having a bottom section supporting a needle element being adapted to penetrate a pierceable seal of a cartridge to be disposed in a cartridge holder of the drug delivery device, wherein the receptacle comprises fastening means for releasably fastening the needle assembly to the cartridge holder, and wherein the fastening means is convertible into a release configuration by way of an elastic deformation of the receptacle.

Abstract: A medical instrument with attached needle of the present invention includes: a needle tube having a needle tip capable of piercing a living body; and a seal member composed of an elastic member and provided to hold an outer surface of the needle tube in a liquid-tight manner in a condition where the needle tip protrudes from one end and a proximal portion on a side opposite to the needle tip protrudes from the other end. The instrument also has: a liquid containing section having a liquid chamber capable of containing a liquid therein; and a needle seating section formed at one end of the liquid containing section. The seal member is in contact with an inner surface of the needle seating section and is disposed within the needle seating section in a compressed state. The proximal portion of the needle tube communicates with the liquid chamber.

Abstract: A needle-based medical device including a needle guide and a method for constructing the same are disclosed. The needle-based medical device includes a tube having a first lumen; a needle guide which is dimensioned to be inserted into the lumen of the tube, and a needle. The needle is inserted such that an end is positioned in the needle guide. A glue may also be provided to secure the needle guide to the tube. In one embodiment, the tube may be made of extruded plastic.

Abstract: Described here are unit dose containers, methods, and kits for treating asthma and other pulmonary conditions by nebulization. The unit doses of active agents are provided in a low volume formulation, which results in faster nebulization of the unit doses. The containers are also formed to minimize internal surface area so that effective re-dispersion of the active agents can be achieved while reducing adsorption to the walls of the containers.

Abstract: This syringe with needle is provided with a needle tube having a needle tip capable of puncturing a living body, and a syringe by insert molding formed integrally with the needle tube. The syringe includes: a main body which is filled with a drug; and a securing section which is formed to be continuous with the main body. The securing section secures the needle tube in a state that the needle tip of the needle tube is protruded. The securing section of the syringe includes a holding hole in which a chuck member for supporting and securing a circumferential surface of the needle tube during the insert molding is inserted and passed.

Abstract: Set for medical treatment by means of a pen-type holder containing a medical in solution for subkutan injection by means of a disposeable needle or cannula assembly engageable on one end of the pen. The set comprises at least one tubular holder (10) in which new or used cannulas can be inserted and stored the holder having firm fastening means (13) to be detachably adapted to the medical pen or other similar holders (10).

Abstract: An adapter mountable to a retractable syringe barrel comprises a body that includes a needle portion and a barrel-engaging portion and a needle aperture. The adapter facilitates mounting a needle assembly to the barrel. The needle assembly comprises a needle body and cannula and an immobile, compressible needle seal, wherein the needle body and the needle seal are releasably engaged. The needle seal is engageable with a needle portion of the adapter. The needle body comprises one or more fluid reclaim channels that facilitate efficient delivery of the fluid contents of the retractable syringe. The retractable syringe also comprises dual locking systems to impede or prevent re-use.

Abstract: A hypodermic needle assembly and a method of delivering a microsphere drug. A hypodermic needle assembly includes an injection needle; an injection device; and a hub defining a cavity including a transition portion having a first end and a second end between the first end and an inlet of the injection needle and having a gradually decreasing diameter from the first end to the second end, wherein the hub is coupled between the injection needle and the injection device such that the first end is in fluidic communication with an outlet of the injection device and the second end is in fluidic communication with the inlet of the injection needle, wherein the diameter of the cavity at the first end is larger than an outlet diameter of the injection device, and wherein the diameter at the second end is substantially the same as an inlet diameter of the injection needle.

Abstract: Apparatus and methods are provided to access bone marrow at various target areas. Such apparatus may include an intraosseous device operable to penetrate bone at a selected target area and a depth limiter operable to control depth of penetration of the intraosseous device into bone and associated bone marrow. A manual driver and a guide may be included to optimize optimum insertion of the intraosseous device at a selected insertion site on a sternum.

Abstract: A luer connector assembly is provided for enhancing the frictional engagement between medical devices such as syringes and needle assemblies. The assembly needle includes a female luer fitting having a passageway and a relatively soft, resilient member bounding the passageway. The passageway is also bounded by the body of the fitting, which is harder than the soft, resilient member. A male luer fitting inserted into the passageway engages both the soft, resilient member and the body of the female luer fitting. A method of manufacturing such a connector assembly is further provided. A first material is injected into a mold to form the body of a female luer fitting, the fitting including a passageway and a recess extending into the body. A second material is then injected such that it extends into the recess and bounds the passageway. The second material, when cool, is softer than the first material.

Abstract: A syringe for delivering medication through an intravenous port, or for providing a combination of medications includes a barrel with a plunger in slidable and sealing engagement therein, and a piercing member formed integrally with the barrel. The piercing member includes a bore in communication with the distal end of the barrel, and a piercing point and an aperture at a distal end of the piercing member. The distal end of the barrel sealingly connects to a transport cap, an intravenous port or an injection needle. The distal end of the piercing member is removable and includes an external recess and a corresponding internal step to define a separation plane for the distal end of the piercing member. The piercing member is used to draw up one or more medications into the barrel, and is then removed to enable the transport cap to be attached to seal the contents.

Abstract: A retractable syringe, comprising a needle having a tip and a base, a needle collar coupled to the needle, the needle collar including at least one groove disposed in a bottom portion of the needle collar and extending from the portion of the needle collar nearest to the base of the needle toward the tip of the needle, a fitting coupled to the needle collar and including a sealing element disposed between a first portion of the fitting and the needle collar, a barrel unit, the barrel unit designed for coupling to the fitting, a plunger unit having a piston on a first end of the plunger unit, the plunger unit and piston being positioned in the barrel unit, an extractor element coupled to the first end of the plunger and having a proximal end adjacent to the plunger and a distal end, the extractor element designed for coupling to the needle collar and encompassing at least a portion of the at least one groove.