Abstract: A medication delivery apparatus for use with a medication container includes a housing, a fluid conduit at least partially extending within the housing and configured to deliver medication within the medication container to a patient, a medication port extending from the housing and configured to be coupled to a fluid outlet of the medication container, the medication port being fluidically coupled to the fluid conduit, and at least one sensor disposed within the housing to generate information characterizing administration of the medication for processing by a remote data collection system. The housing can have a size and shape that enables it to be supported by a first hand of a user while the user administers the medication from the medication container via the medication port using a second hand of the user. Related apparatus, systems, and techniques are also described.

Abstract: Systems include integrally sealed medicinal storage containers, including one or more segments of an ultra efficient insulation material, the one or more segments having one or more surface regions, the one or more segments principally defining at least one storage region, and one or more regions of substantially thermally sealed connections between at least one of the one or more surface regions of the one or more segments wherein the one or more regions of substantially thermally sealed connections and the one or more segments form an integrally thermally sealed medicinal storage region.

Abstract: The calibrated medicine mixing assembly preferably includes a primary reservoir having a primary cavity adapted to receive the fluid. The primary reservoir preferably including calibrated fluid level indicia displayed on an outer surface. Such an assembly may further include a secondary reservoir preferably having a secondary cavity adapted to receive the powder agent. The secondary reservoir preferably including calibrated level indicia displayed on its outer surface. The secondary reservoir is further removably positioned into the primary reservoir such that a major surface area of the secondary reservoir is completely submerged inside the primary reservoir. A plurality of orifices may preferably be formed along a top region of the secondary reservoir, the orifices further situated inside the primary reservoir, thereby causing the secondary cavity to be in fluid communication with the primary cavity when the secondary reservoir is situated within the primary reservoir.

Abstract: A container having multiple compartments formed by frangible seals in the interior chamber of the container is disclosed. The container comprises an indicator adapted to provide an indication that a seal breach between the chambers has occurred. Methods of forming a container having a seal breach detection indicator are also disclosed.

Abstract: A medication injection site is provided that includes a medication port and an identification sensor. The medication injection site, when coupled to a medication container, can wirelessly transmit data characterizing the contents of the medication container to a remote data collection system. The housing of the medication injection site has a shape and size enabling it to be held by a first hand of a user while the user administers medication from the medication container via the medication port using his or her second hand. The housing can include a disposable sub-housing and a reusable sub-housing such that the reusable sub-housing is used by many patients. In some implementations, the medication injection site can be placed on an IV drip line. Related apparatus, systems, and kits are also disclosed.

Abstract: A kit of parts for an injection safety system comprises a vial comprising a container for storing an injectable substance, and an identifier removably secured to the container. The identifier comprises an indicium of the substance, and an engagement portion. The kit of parts further comprises a syringe for drawing the substance from the vial. The syringe comprises a mating engagement portion. The mating engagement portion is mateable with the engagement portion to secure the identifier to the syringe and transfer the identifier from the vial to the syringe.

Abstract: Medication errors happen frequently in hospital, home, and pharmacy environments. A medication verification and dispensing system provides protection against such errors. The apparatus includes a guide tube that receives a medication and imaging device(s) adjacent to the guide tube that take image(s) of the medication. The imaging devices(s) and light source(s) are oriented for capturing images that reveal markings, color, size, shape, etc., of the medication. A verification system uses a signature of the image to identify the medication or compares the image(s) to reference images to identify the medication and to a prescription record of the patient to ensure it is a correct medication, dose, amount, timing, etc., for administration. If the medication is correct, it is dispensed into a dispensing vessel that locks the medication inside, but unlocks when it recognizes a unique patient identifier worn by a patient that is a correct recipient for the medication.

Abstract: Apparatus, systems, methods and articles are described to prepare and track medications and medication containers as they are prepared, administered to patients and, in some cases, disposed of. Information such as medication type, concentration, and volume are associated with medication containers during preparation and this information can later be consumed/utilized when administering the medication from a container to a patient. Disposing of any remaining medication can also be tracked.

Abstract: A container (10) comprising a plurality of compartments (A, B, C) separated by compartment dividers (6), and an inlet connector (3) for receiving a liquid via a connection tube (2). The compartment dividers rupture when a sufficient pressure is applied by a liquid or gas introduced into the container (10) through the inlet connector (3). Some of the compartments comprise powder, which dissolves at the introduction of liquid into the container. A system, process and use in the field of dialysis are also disclosed.

Abstract: A label enables a user to recognize information necessary when using a medicine bag in a reliable fashion. The label includes a base part indicating thereon basic information including at least information on ingredients of medicines accommodated in a medicine bag and a detachable part detachably joined to the base part. The detachable part is so shaped as to be attachable to such an area of the medicine bag that it becomes difficult to use the medicine bag when a surface of the area is covered, and the detachable part indicates thereon characteristic information including at least directions on use of the medicine bag.

Abstract: This invention relates to medical devices for labelling a syringe filled from an ampoule, and to safer devices for filling a syringe from an ampoule, and to associated methods. We describe a device for attaching to an ampoule to label a syringe filled from the ampoule, the device comprising: an ampoule-mounting portion for mounting the device to a filled ampoule; a syringe-fitting portion to enable the device to be fitted onto said syringe; and a label holder to hold a label for contents of said ampoule; and wherein one of said syringe and said ampoule is detachable from said device; and wherein said label is configured such that in conjunction with a filling operation of said syringe and detachment of said one of said syringe and said ampoule from said device said syringe is labelled by said label.

Abstract: A transfer guard may provide a fluid path from a vial to a reservoir containing a plunger head connected to a plunger arm operatively engagable with a handle that at least partially covers a casing configured to allow the handle to operatively engage the plunger arm to move the plunger head to transfer fluidic media from the vial to the reservoir. A support structure may have a chamber, a first adapter for mating with a vial containing fluidic media, and a second adapter for mating with a reservoir containing a plunger head moveable within the reservoir. A first needle may provide a fluid path from the vial to the reservoir and a second needle may connect the vial and the chamber containing an air flow control mechanism for allowing air to flow in one direction.

Abstract: The present disclosure provides for an airless intravenous (IV) bag which contains a specialized device, referred to herein as the airless intravasculature infusion device (AIVID). The AIVID allows one to view the amount of fluid in the IV bag but substantially decreases or completely prohibits the risk of an inadvertent air infusion into a patient.

Abstract: A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular contour in the housing. The outer diameter of the protrusion on the distal end of the cartridge is chosen as a larger diameter for a higher concentration of insulin. In this way only a cartridge containing the correct concentration or a lower concentration fits into a delivery system designed for a specific concentration of insulin.

Abstract: An apparatus includes a detecting electrode, a liquid sensing module, and a connecting means. The detecting electrode is attached to an outer surface of an intravenous drip container. The liquid sensing module includes a clock generator generating a clock signal, a waveform generating circuit coupled to the detecting electrode to generate an analog driving signal by using the clock signal, a grounding electrode grounded through the waveform generating circuit, an analog-to-digital converter converting the analog driving signal to a digital voltage signal, and a capacitance determining circuit receiving the digital voltage signal to determine a value of a capacitance of a capacitor formed by the detecting electrode and the grounding electrode. The connecting means connects the detecting electrode to the liquid sensing module.

Abstract: A cartridge having a distal end provided with a mechanical coding. The coding has the form of a circular protrusion where the circular outer diameter is dedicated a specific concentration of insulin contained in the cartridge. The distal end of the cartridge is fitted in to a circular contour in the housing. The outer diameter of the protrusion on the distal end of the cartridge is chosen as a larger diameter for a higher concentration of insulin. In this way only a cartridge containing the correct concentration or a lower concentration fits into a delivery system designed for a specific concentration of insulin.

Abstract: A cartridge is engageable with a medical device, the cartridge comprising an ordered arrangement of N electrical components (540) each with different respective values of an electrical property, and an ordered arrangement of N conductors (522, 524, 526) operably coupled to the ordered arrangement of the N electrical components.

Abstract: A single-use indicator is provided and is particularly well suited for use with a surgical catheter device. The indicator includes an absorbent filament or wick which is placed in a transparent or translucent indicator lumen of a multi-lumen catheter. The lumen is provided with at least one side port. When the catheter is inserted into a blood vessel, blood enters the indicator lumen through the side port and is absorbed by the filament, thus turning the filament red or purple in color. When the instrument is removed from the blood vessel, the stained filament is clearly visible as an indicator that the instrument has been used. Because the filament is trapped inside a lumen of a relatively long catheter, it is difficult or impossible to remove it during a remanufacturing process.

Abstract: Device (5) for filtering blood including a filter unit (7) having a blood filter, an inlet (8) for blood to be filtered and being connectable to an artery of a patient and a blood outlet (9) for filtered blood and being connectable to a vein of the patient, and having a filtrate container (6,14), that encloses the filter unit (7), for receiving filtrate (12) passing through the blood filter during a filtering process and that the filtrate container (6,14) is a closed container, which in a filled state is arranged to establish a counter-pressure over the blood filter, whereby the filtering process is interrupted. The invention also concerns a system including the above device.

Abstract: Ambulatory infusion pumps, pump assemblies, cartridges, baseplates, cannulas, insertion tools, and related components as well as combinations thereof and related methods.

Abstract: Fill stations and base stations are provided for personal pump systems. The fill stations may be opened and closed to accept a reservoir and to allow fluid to be introduced into the reservoir for use with personal pump systems. The fill stations may hold the reservoir at a tilt relative to an underlying surface and may discourage overfilling of the reservoir. The filling stations may also include viewing windows having fluid lines marked thereon for indicating volume of fluid within the reservoir.

Abstract: The present invention relates to a connector device suitable for connecting an enteral administration set to a laminated paper packaging system comprising enterally administrable medical or nutritional food.

Abstract: NuChain supply chain and disposal chain apparatus are created by NuPurposing containers, conditioning and transforming such containers from fluent material delivery containers into waste collection containers. Novel structural features of the waste collection systems allows bottle docking for the ingress of collection material into fluent material distribution containers as well as operation as a canister waste ingress collection system. The application of counter opposing forces on a canister and a lid operates in sealing and the unsealing and assembly and disassembly. A reduced pressure configured to be drawn away from said container inducing ingress of air into said container by a source of reduced pressure.

Abstract: The present invention relates to a portable kit and methods for administering a therapeutic dose of autologous plasma to an injured person.

Abstract: A medication and identification information transfer system is provided that includes a medication vial, a secondary medication container (syringe) and a medication information transfer apparatus. The medication information transfer apparatus, when coupled to a vial, can transfer information indicative of the contents of the vial to an intelligent injection site. The medication information transfer apparatus has a shape and size enabling it to be connected to a vial adapter for removal of medication from the vial transfer it to a syringe for delivery to an injection site while simultaneously transferring information about the medication in the vial to the injection site. In some implementations, the medication injection site can be placed on a fluid delivery line for infusion into a patient. Related apparatus, systems, and kits are also disclosed.

Abstract: A light sensitive media packaging with unique shrink-wrap light protection label that works as a light barrier to protect media from light damage.

Abstract: A portable blood storage device includes an outer housing an inner housing. The outer housing defines the structure of the blood storage device. The inner housing is located within the outer housing and has an interior cavity for storing collected blood and/or blood components. The inner housing has an open top to allow access to the interior cavity. The storage device also has an inlet duct and a return duct located within the interior cavity. The inlet duct is fluidly connectable to a cooling device and brings conditioned air into the storage device when fluidly connected to the cooling device. The return duct is also fluidly connectable to the cooling device and returns exhaust air to the cooling device when fluidly connected.

Abstract: A drug administration safety device having a label configured to be attached to a drug container such as a syringe or IV bag, an adhesive on the back face of the label, and a backing or substrate for holding the label and protecting the adhesive prior to the application of the label to the drug container. In one embodiment, the label includes a first drug name section in a first orientation, a second drug name section in a second orientation, a third drug name section in a third orientation, a drug concentration section, a variable information section, and a gradiation viewing section. The first orientation, second orientation, and third orientation are different from each other to enable a user to readily see the drug name regardless of the position and orientation of the drug container.

Abstract: A method of treating Multiple Sclerosis is disclosed. The method comprises administering to the subject a therapeutically effective amount of SDF-1 alpha. An article of manufacture comprising SDF-1 alpha and an anti-Multiple Sclerosis agent is also disclosed.

Abstract: Provided herein are methods of treatment of a cystic disease by administering a compound of Formula I. In certain embodiments, the compound for use in the methods provided herein is roscovitine or an analog thereof.

Abstract: A test for diagnostic tests, particularly for testing blood prior to a transfusion is disclosed. The test element includes at least two test units for carrying out at least two tests. The test element is provided with a fixing means for fixing the test element.

Abstract: In a peritoneal dialysis embodiment of the present invention, spent dialysate from the patient's peritoneal cavity passes, along a patient loop, through a dialyzer having a membrane that separates waste components from the spent dialysate, wherein the patient loop returns fresh dialysate to the patient's peritoneal cavity. The waste components are carried away in a second regeneration loop to a regeneration unit or sorbent cartridge, which absorbs the waste components. The regeneration unit removes undesirable components in the dialysate that were removed from the patient loop by the dialyzer, for example, excess water (ultrafiltrate or UF), toxins and metabolic wastes. Desirable components can be added to the dialysate by the system, such as glucose and electrolytes. The additives assist in maintaining the proper osmotic gradients in the patient to perform dialysis and provide the necessary compounds to the patient.

Abstract: The present invention monitors an IV bag injection port and informs the user of prior injections. The present invention employs an object and/or a sealed chamber within a transparent IV fluid bag injection port. In the case of the object, notification of prior use is achieved when the object's or IV fluid's appearance is altered. With respect to the sealed chamber, the chamber's seal is breached to allow fluid to pass between the chamber and the IV bag to change the appearance of the contents of the chamber. Since the injection port and bag walls are at least partially transparent, medical personnel are able to observe the altered appearance of either the object, IV fluid or the sealed chamber.

Abstract: Fluid communication devices may be provided for use with intraosseous devices. Apparatus and methods may also be provided to communicate fluids with an intraosseous device.

Abstract: The calibrated medicine mixing assembly preferably includes a primary reservoir having a primary cavity adapted to receive the fluid. The primary reservoir preferably including calibrated fluid level indicia displayed on an outer surface. Such an assembly may further include a secondary reservoir preferably having a secondary cavity adapted to receive the powder agent. The secondary reservoir preferably including calibrated level indicia displayed on its outer surface. The secondary reservoir is further removably positioned into the primary reservoir such that a major surface area of the secondary reservoir is completely submerged inside the primary reservoir. A plurality of orifices may preferably be formed along a top region of the secondary reservoir, the orifices further situated inside the primary reservoir, thereby causing the secondary cavity to be in fluid communication with the primary cavity when the secondary reservoir is situated within the primary reservoir.

Abstract: A system for identifying a reservoir used with a fluid delivery device. The system includes a reservoir comprising a housing for holding fluid and a colored marking located on a surface of the housing. A fluid delivery device includes a compartment for receiving and operatively coupling with the reservoir. A light source shines light on the colored marking of the reservoir. A color sensor detects wavelengths reflected and/or refracted from the colored marking due to the light shined on the colored marking. A processor of the delivery device determines a color of the colored marking from the detected wavelengths and ascertains information related to the reservoir or the fluid in the reservoir corresponding to the determined color, wherein the processor operates the fluid delivery device according to the ascertained information, wherein the information may include a reservoir type and/or medication type.

Abstract: The present invention monitors an IV bag injection port and informs the user of prior injections. The present invention employs an object and/or a sealed chamber within a transparent IV fluid bag injection port. In the case of the object, notification of prior use is achieved when the object's or IV fluid's appearance is altered. With respect to the sealed chamber, the chamber's seal is breached to allow fluid to pass between the chamber and the IV bag to change the appearance of the contents of the chamber. Since the injection port and bag walls are at least partially transparent, medical personnel are able to observe the altered appearance of either the object, IV fluid or the sealed chamber.

Abstract: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent.

Abstract: A portable shatter-proof container for liquid medication is adapted for measuring, labeling, and dispensing single dosages of prescribed medication. The apparatus is comprised of a three-dimensional graduated tube having a snap-closure lid and a base for allowing the apparatus to stand upright. The tube has graduated marks in imperial and metric measurements and can hold a reasonable volume, i.e. one dose, of liquid. With its rectangular shape, the narrow length contains the graduated markings of imperial measurement on one side and metric markings on the opposing side. The wider front includes an adhesive label for writing information such as patient name, date, contents, and dosing instructions. Liquid medicine is poured directly from the original medicine bottle into the apparatus, thereby allowing for measurement of contents as it is filled. The snap-closure lid allows the container to be transported, without concern of spillage.

Abstract: A priming indicator for a fluid infusion system includes a luer cap or other component of the infusion system having an indicator surface covered by a membrane. The membrane exhibits a first visual characteristic, such as being opaque, when dry and exhibits a second characteristic, such as becoming less opaque, when wet. Once the membrane becomes wet, indicia on the surface, which may be provided on a rod at least partially covered by the membrane, becomes visible, thereby indicating an intravenous tube to which the luer cap is secured has been primed or is nearly primed. The indicator may alternately be employed at an upstream end of an infusion set, such as at the port of a medical bag providing a supply of fluid, to indicate a low level of fluid in the medical bag.

Abstract: A sterilization challenge specimen holder is used with a test indicator to challenge sterilization on a consistent basis. The holder includes a body having an internal chamber region and a sleeve positionable within the internal chamber. A cap is sealable on the holder and a plug is positioned in the body. The plug has a wall having a spiral formed groove therein in communication with the internal chamber region. An opening in the holder provides for a flow path for communication between the environs and the internal chamber, and another opening(s) provides for a second flow path for communication between the internal chamber and the inner chamber of the sleeve. An indicator tube carries a biological indicator and has openings therein.

Abstract: The present device is a suppression device for containing sound and germs emanating from a user's cough. A substantially hollow tube forms a gas conduit with a gas-permeable end membrane fixed within the tube across the gas conduit. A layer of a gas-permeable anti-bacterial material is fixed within the tube against the end membrane and a gas-permeable filter material is fixed within the tube against the anti-bacterial material. When a user needs to cough, the user coughs into the suppression device whereby the emanating germs and sound are suppressed as they encounter the filter material, the anti-bacterial material, and the end membrane. The suppression device further includes a lanyard permitting a user to wear the device and a label to write the user's name on the device. The suppression device is primarily comprised of biodegradable materials, allowing the suppression device to be disposable in an environmentally friendly way.

Abstract: A blood container and a method is provided for a blood transfusion, in particular, for a blood transfusion by which blood a patient is losing is collected, fat is separated from the blood, and the non-fat blood is transfused into the patient so as to prevent side-effects including fat embolism and the like from occurring due to the fat after the blood is transfused into the patient. The blood container includes a soft case and hard case. A first tube is formed at one side of the hard case to inject blood into the soft and hard cases and a second tube is formed adjacent to the first tube to discharge the blood out of the soft and hard cases, wherein the soft and hard cases have open side that adhere to each other to form a single body.

Abstract: A selected substance is dissolved into a given injectable fluid medication having an initial clear visual appearance. The selected substance is selected from a group of substances which, when dissolved in the injectable fluid medication, will alter the clear appearance to produce a non-clear or altered visual appearance. The altered visual appearance could be a color, which, by code, identifies the given injectable fluid medication, and distinguishes the given injectable fluid medication from a different injectable fluid medication, the clear visual appearance of which has been altered by dissolving another selected substance to produce a colored visual appearance different from the color of the altered visual appearance of the given injectable fluid medication.

Abstract: A drug administration safety device having a label configured to be attached to a drug container such as a syringe or IV bag, an adhesive on the back face of the label, and a backing or substrate for holding the label and protecting the adhesive prior to the application of the label to the drug container. In one embodiment, the label includes a first drug name section in a first orientation, a second drug name section in a second orientation, a third drug name section in a third orientation, a drug concentration section, a variable information section, and a gradiation viewing section. The first orientation, second orientation, and third orientation are different from each other to enable a user to readily see the drug name regardless of the position and orientation of the drug container.

Abstract: An environmental sensor device for detecting environmental conditions within a pharmaceutical product package is described. The sensor device is a stand alone device that includes: a housing defining the outer dimensions of the sensor device, a humidity sensor, a temperature sensor, a control circuit, a memory circuit, a power source and a communications interface. The housing has outer dimensions that allow it to fit inside a pharmaceutical product package. A system and method for evaluating best before date for pharmaceutical products are also described.

Abstract: Safety apparatus for transfusions of blood or blood derivatives contained inside at least one bag (1) having at the bottom at least one tube (2) made of elastically deformable material such as rubber or the like, for discharging the blood or blood derivatives; said blood or blood derivatives belong to a given blood group with an associated Rh factor; said apparatus comprises a constriction device (3) closed by suitable clamping means (14, 15) movable about said tube (2) so as to prevent the blood or blood derivatives which leave the bag (1) from passing through said tube (2); said constriction device (3) is provided with a seat (4) on which suitable elements (6,7) for coding and identifying said blood group with associated Rh factor are formed, which elements co-operate with a unique key (19) which establishes the identity of the blood group of the patient and, in the event of compatibility, allows opening of said constriction device (3) provided with suitable elements (5, 21, 22) complementing said coding el

Abstract: A pre-evacuatable or pre-evacuated container for medical purposes is provided. The container comprises a container body which is open at one side with a peripherally extending container wall and a bottom, and a cover element. The peripherally extending container wall of the container body has an end groove, into which a sealing element for sealing off the container body with respect to the cover element is or can be inserted.

Abstract: A self-powered, enteral tube feeding device. The device includes a fluid container and a removable lid for pressure sealing the container. The device also includes a fluid exit port and a flexible tube providing fluid communication from the exit port of the device to a through-the-abdominal-wall port of a patient. Fluid is forced out of the container and into the patient's stomach or small intestine with air pressure provided by a finger-operated flexible bulb-type pressurizer unit having two air check valves. The device is preferably operated by the user without assistance. In preferred embodiments the device also includes alarm features that provide a warning when the fluid level is approaching the exit port so that no air is pumped into the user's abdominal cavity. In one preferred embodiment these alarm features include a magnetic switch located below the fluid container and a magnet floating within the container vertically over the switch and on or near the surface of the fluid.

Abstract: A system for facilitating preparation of medication doses comprising a container of for receiving a quantity of medication, the container having color bands extending circumferentially therearound to facilitate preparing medication doses, each color band corresponding to a predetermined dosage of medication.