Abstract: The present invention relates to a connector for a replaceable container to be used in a medical machine, which is comprised by at least a body, the inner side of which is traversed by inlet and outlet tubes extending from within such container towards an outer side of the connector, wherein said tubes separately extend leading to two laterally spaced-apart apertures that are removably attachable to a mounting means and supplementary connection of said machine.

Abstract: A multi-chamber container includes a medical bag made of a flexible film for storing medicines, and an outlet port mounted to the bag for discharging medicines. The bag has partition wall dividing the bag into compartments for medicines, the wall has welded portion separated by pressing to the bag, the port has extended portion extending to inside the bag and closure member integral with the port and having U-shaped profile, the member has sealed point connected to the bag such that the member is opened by expansion of the bag when the wall separates, the extended portion has recess and thin wall portion connecting to the member, the thin wall portion is broken by the expansion of the bag such that the member is pulled by the sealed point, hinges at the recess and is opened, and the sealed point is positioned away from the recess and toward the wall.

Abstract: A container for use in dialysis, containing a certain amount of a salt concentrate in the form of a powder, granules or tablets or mixtures thereof, having an inlet for the water and an outlet that is connectable to a dialysis machine. Both the inlet and the outlet are situated on one side of the container, and each includes a filter therein to prevent any undissolved salt concentrate from leaving the container.

Abstract: A multi-cell container includes a bag of substantially flat shape made of flexible film, a partition wall as a separable seal welding opposite inner surfaces of the bag and dividing an inner space of the bag into a plurality of compartments and an inlet-outlet port located at a periphery of the bag so as to be opened to one of the plurality of compartments for introduction and/or discharge of liquid. The partition wall has a horizontal section extending in a direction along the bottom of the bag and a vertical section bent therefrom and extending to the topside of the bag. A first larger volume compartment is formed on one side of the partition wall adjacent the bag bottom and a second smaller volume compartment is formed on the other side of the partition wall. The inlet-outlet port is opened to the first chamber.

Abstract: The subject matter of the invention is a container system having an inner container for receiving ready-to-use liquid, in particular dialysis liquid, and an outer container surrounding the inner container to receive spent liquid such that the inner container has through-openings which establish a fluidic connection for the liquid in the outer container.

Abstract: The subject of the invention is a bag for receiving, preparing and producing dialysis fluid. The invention relates in particular to a bag having a sealing bordering line and a flexurally rigid hard plastic part connected to the film material. The hard plastic part is connected to the film material separately from the sealing bordering line and offers an area for gripping the bag for fastening it without having to act mechanically on the sealing bordering line in a direct manner.

Abstract: The present invention relates to a bag (1) for packaging a biological substance, such as animal semen, which is formed by two plastic walls (10, 11) assembled so as to define a pouch (P) for receiving said substance and that comprises a line (15) communicating with said pouch (P) a line for filling the same, this bag comprising in addition at least one pair of openings (3, 4) located on both sides of said line (15), in order to get hung, via these openings, to fingers that are complementary to a supporting device. This bag is characterized in that at least one of these openings (3, 4) has an oblong shape, extends perpendicularly to said line (15), and comprises an area forming a hard spot. The invention relates also to a strip formed by juxtaposing such bags (1), and an assembly comprised of a bag and a hanging support.

Abstract: The present disclosure provides for an airless intravenous (IV) bag which contains a specialized device, referred to herein as the airless intravasculature infusion device (AIVID). The AIVID allows one to view the amount of fluid in the IV bag but substantially decreases or completely prohibits the risk of an inadvertent air infusion into a patient.

Abstract: The present invention relates to a multilayer film for medical solution container and a container comprising the same, more particularly, to the multilayer film for medical solution comprising an outer layer comprising polypropylene, polypropylene copolymer or a mixture thereof; an intermediate layer comprising a mixture of 30˜70% by weight of propylene-based polymer including polypropylene, polypropylene copolymer or a mixture thereof, and 30˜70% by weight of a thermoplastic elastomer; and an inner layer comprising a mixture of 50˜70% by weight of propylene-based polymer including polypropylene, polypropylene copolymer or a mixture thereof, 5˜20% by weight of polyethylene, and 10˜45% by weight of a thermoplastic elastomer.

Abstract: A multiple chamber container for separately storing components of a parenteral nutritional formulation is provided. The multiple chamber container may include frangible barriers, preferably peelable seals separating the chambers from each other. The container preferably facilitates the selective activation of the peelable seals to permit the admixing of less than all the separately stored components. The container may include a chamber positioned at each of the opposite lateral ends of the container and at least one additional chamber between the lateral chambers. The at least one additional chamber may have a longitudinal length substantially less than the longitudinal length of at least one of the lateral chambers. This configuration allows for selective opening of the seals since when rolling the container from the top avoids pressurizing the at least one additional chamber and inadvertent activation of a seal.

Abstract: The present invention relates to a process of fusion-bonding a plastic film (8a, 8b) to an object to be fusion-bonded such as a port member (16) in manufacturing a drug bag, and relates to a drug bag. The present fusion-bonding process comprises steps of disposing a heat generation element generating heat by absorbing infrared laser, on an opposite surface (8c) of the plastic film (8a, 8b) from the port member (16), or between the port member (16) and the plastic film (8a, 8b), pressing a press member (30a, 30b), which allows infrared laser to be transmitted therethrough, from a side of the plastic film (8a, 8b), and irradiating the infrared laser (L) to the heat generation element (24a, 24b) through the press member (30a, 30b).

Abstract: In a blood bag system mounted in a centrifugation and separation apparatus, a filter is settable in different appropriate orientations at storage time and usage time, and first and second tubes and a filter are arranged respectively in appropriate orientations during use. The blood bag system includes a BC pooling bag for centrifugation of buffy coat, the filter for removing white blood cells from a supernatant liquid transferred from the BC pooling bag, a platelet preserving bag for reserving the supernatant liquid that has passed through the filter, the first tube connecting the BC pooling bag and an inlet of the filter, the second tube connecting the platelet preserving bag and an outlet of the filter, a cassette fixable in the centrifugation and separation apparatus, an attachment for holding the filter, and a hinge section tiltable relative to the cassette with reference to an axis in the circumferential direction.

Abstract: A storage bag for containing biologic content having a first chamber operable to contain the biologic content, a second chamber separate from the first chamber, and a first fluidic seal system disposed between the first chamber and the second chamber. The first fluidic seal system is positionable between a first position retaining the biologic content in the first chamber and preventing the biologic content from entering the second chamber and a second position permitting at least a portion of the biologic content to flow from the first chamber to the second chamber.

Abstract: A flexible container receives a liquid material, which is freeze-dried in situ within the flexible container. A gas permeable material that is separate from the flexible container provides gas transport for sublimation during drying and lyophilization. The gas permeable portion of the system can be isolated and removed from the flexible container post-lyophilzation The freeze-dried material is stored in the flexible container until administration is necessary. The flexible container receives a reconstituting liquid for mixing with the freeze-dried material, and conveys the reconstituted freeze-dried material from the flexible container for administration to an individual.

Abstract: A clamp for a blood bag system includes a protrusion section which presses a tube, a locking section having a first engagement section and a second engagement section that form therebetween an engagement groove in which the protrusion section is positioned and by which engagement can be made, a first engagement release section which releases an engaged state between the first engagement section and the protrusion section; and a second engagement release section which releases an engaged state between the second engagement section and the protrusion section.

Abstract: A reagent supply arrangement for a hemodialysis system may include an E-prong connector having three parallel prongs with two outer prongs arranged in a common plane and a center prong arranged above the common plane, a first supply line for a first reagent connected in fluid communication with one of the outer prongs, a second supply line for a second reagent connected in fluid communication with the other of the outer prongs, a liquid line connected in fluid communication with the center prong, and a container for housing the first reagent having an inlet connected to the liquid line and an outlet connected to the first supply line for the first reagent. The E-prong connector may help prevent the improper connection to the dialysis unit, e.g., because the prong arrangement ensures connection in only one way to the dialysis unit.

Abstract: This invention is directed to a method of collecting and separating whole blood into components. The method includes the steps of adding an anticoagulant having an acidic pH to a bag for collecting and/or separating whole blood, collecting whole blood in the bag, loading the bag containing anticoagulated whole blood on a rotor, spinning the bag on the rotor to separate the whole blood into at least one component; and squeezing the bag on the rotor to push the component from the separation bag into at least one satellite bag.

Abstract: A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space.

Abstract: A portable device for mixing a dilute disinfectant solution comprising a first reservoir comprising a predetermined amount of said disinfectant solution, a chamber which is connected to said first reservoir and which holds a predetermined amount of dilutant, and means for discharging said predetermined amount of said disinfectant solution from said first reservoir into said chamber to be mixed with said predetermined amount of dilutant in said chamber wherein said device provides the dilute disinfectant solution at a fixed dilution determined by the ratio of the predetermined amount of said disinfectant solution to the predetermined amount of dilutant.

Abstract: A multilayer film for medical purposes is proposed, with one or two external layers, wherein the external layers contain: a first polyalphaolefin; a first thermoplastic elastomer with a melt viscosity of a melt flow index according to ISO 1133 of from 0.001 to 6 g/10 min at 230° C., 2.16 kg; and a second thermoplastic elastomer with a high melt viscosity not measurable according to ISO 1133 which is higher than the melt viscosity of the first thermoplastic elastomer.

Abstract: Provided is a solid antimicrobial agent suitable for portable use, which can continuously release a stable amount of chlorine dioxide even under vibration or shock. An antimicrobial pouch includes: an antimicrobial agent supporting an antimicrobial substance in a porous inorganic solid carrier; a first pouch body receiving the antimicrobial agent; and a second pouch body receiving the first pouch body, wherein the first pouch body includes fine holes on an entire surface, the fine holes having a diameter smaller than a particle size of the inorganic solid carrier, and the second pouch body includes release holes at an edge portion, the release holes through which the antimicrobial substance is released to atmosphere of the second pouch body.

Abstract: The invention includes a bag system for collecting a biological fluid, in particular blood. The system includes a device for collecting the fluid which is in fluid communication with at least one fluid collection bag, and a device for sampling the fluid to be collected which includes at least one sampling receptacle. The sampling device includes a device for transferring the fluid from the bag system into the sampling receptacle or receptacles, in which the transfer device is provided with a device for associating the receptacle or receptacles. The transfer device may be arranged to allow the support of the receptacle or receptacles in a standby position, the guidance of the receptacle or receptacles to a transfer position and, after transfer, the dissociation of the receptacle or receptacles from the bag system.

Abstract: The present invention refers to a flexible multiple chamber bag for storing medical products comprising two or more chambers.

Abstract: The present invention provides an enteral feeding set comprising tubing adapted for fluid flow therethrough and further adapted to be engaged by a pump unit, a valve mechanism in direct communication with said tubing, said valve mechanism being adapted to be engaged by said pump unit, and a feeding set indicator for permitting identification of the functional configuration of said administration feeding set by said pump unit, characterized in that said tubing comprises at least two inlet tubes on an upstream side of said valve mechanism and a single outlet tube on a downstream side thereof and wherein said inlet tubes each include a connector for connecting said tube to a supply of fluid at a connection end thereof, each of said connectors being of like form but visually distinguishable for indicating to a user which supply of fluid each connector should be attached thereto.

Abstract: A multi-chambered container for medical use (10) includes a container main body (20) having flexibility, a weak seal part (26) that is detachable and seals opposing faces of the container main body, drug storing chambers (22, 24) formed in such a way that the container main body is partitioned into two or more by the weak seal part, and a pair of resonance tags (30, 40) that are provided in the container main body so as to interpose the weak seal part.

Abstract: A container (10) comprising a plurality of compartments (A, B, C) separated by compartment dividers (6), and an inlet connector (3) for receiving a liquid via a connection tube (2). The compartment dividers rupture when a sufficient pressure is applied by a liquid or gas introduced into the container (10) through the inlet connector (3). Some of the compartments comprise powder, which dissolves at the introduction of liquid into the container. A system, process and use in the field of dialysis are also disclosed.

Abstract: A multiple-chamber medical container 1 comprises a container body 5 having two chambers 9, 11 for containing medicaments therein and a partitioning weak seal portion 13 for separating the chambers 9, 11 from each other, a medicinal outlet portion 7 attached to the container body 5 for discharging the medicaments from the chambers therethrough, and an openable small container 15 disposed in the first chamber 9 and having a medicament enclosed therein, the partitioning seal portion 15 being openable so as to cause the chambers 9, 11 to communicate with each other for use. The small container 15 can be opened by opening the partitioning weak seal portion 13.

Abstract: A drug container of a multilayer film including a first layer (1) composed of a linear ethylene/?-olefin copolymer having a density of 0.930 to 0.950 g/cm3, a second layer (2) and a fourth layer (4) each composed of a mixture containing a linear ethylene/?-olefin copolymer having a density of 0.860 to 0.920 g/cm3 in a weight ratio of 95:5 to 40:60, a third layer (3) composed of a polycycloolefin, and a fifth layer (5) composed of a mixture containing a polyethylene and a polypropylene, the fifth layer 5 serving as an innermost layer.

Abstract: The invention provides container systems, kits and methods for peritoneal dialysis (PD) solutions. Such a system, for example, includes a first compartment that contains a PD osmotic agent and a second compartment that contains a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. The invention provides, in other aspects, such systems, kits and methods that provide protective structure which inhibits breaking of a seal prior between the second compartment and an outlet of the system, prior to breaking of a seal between the first and second compartments.

Abstract: Method of dissolving/mixing of a concentrate in/with a fluid in a multi-chamber bag and a method for the production of a medical fluid, in particular a dialysis fluid, in a multi-chamber bag. Moreover, the multi-chamber bag itself is disclosed. In all embodiments, at least two different concentrates can be included separately in powder form, liquid form or semi-liquid slurry form for dissolution in a fluid in the multi-chamber bag. In addition, the use of the multi-chamber bag in haemodialysis or peritoneal dialysis or a haemodialysis or peritoneal dialysis device, in particular as a container for a dialysis fluid in a haemodialysis or peritoneal dialysis device, is described.

Abstract: A blood bag system includes: a first bag in which blood containing multiple components is stored; a second bag in which a relative medium-density component is stored; a third bag in which a relative low-density component is stored; a first tube through which the relative low-density component and the relative medium-density component are transported from the first bag to the second bag; and a second tube through which the relative low-density component is transported from the first bag to the third bag. A blood treatment method involves: centrifuging blood containing multiple components in a first bag, transporting a low-density component from the first bag to a third bag through a first tube and transporting a relative medium-density component from the first bag to the second bag through the first tube.

Abstract: The subject matter of the present invention is a multichamber container and a method for preparing medical fluids composed of concentrates which make a contribution toward the electrical conductivity of the solution and are additionally prepared from concentrates which do not make a contribution toward the electrical conductivity of the solution. The inventive multichamber container is characterized in that it is constructed by dividing the solution components into multiple chambers, so that following the dissolving due to breaking open of the first chamber border of a solution component, which makes a contribution toward the electrical conductivity of the medicinal solution, another chamber border of another solution component which does not make any contribution toward the electrical conductivity of the solution is broken open.

Abstract: An ampoule made of plasties material, for liquid or suspension pharmaceuticals, has a reservoir linked to a removable head by a channel in a neck portion. The channel has a trap, thus located between its reservoir and the head, in the form of an elongated restriction and/or a bend to trap liquid or suspension which may settle during storage, and prevent either reaching the head.

Abstract: Provided a port member for an infusion solution bag that is capable of suppressing occurrence of gaps or wrinkles in a sealed portion in a manufacturing process, and preventing damages to resin sheets of a bag body during storage or transportation. A port member for an infusion solution bag includes a tubular body portion having one end sealed by a plug member structured to enable a hollow needle to be pierced into the plug member, and a tubular to-be-sealed portion continuously formed with an other end of the body portion and having an inner space communicated with the inside of the body portion, the to-be-sealed portion being held between and sealed to end portions of resin sheets overlapped together to form a bag body having an inner space for accommodation of at least a medicine, in which the to-be-sealed portion thus sealed has a radially flattened shape.

Abstract: A self standing bag having two side wall sheets and a bottom sheet. To flatten the bag, the bottom sheet is sandwiched between the two side wall sheets and symmetrically folded along a line parallel to its bottom edge, separating the bag into a four-layer part and a two-layer part. In the two-layer part, the bag includes first sloped sealing lines extending between a first two points on the top edges of the side wall sheets and spaced from the vertical side wall edges by a first distance, to a second two points spaced from the vertical edges of the side wall sheets by a second distance less than the first distance. The four-layer part includes second sloped sealing lines extending between the second two points and a third two points on the bottom edges of the side wall sheets.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: A multiple chamber medical fluid bag includes: (i) a flexible enclosure; (ii) a first fluid chamber formed in the enclosure; (iii) a second fluid chamber formed in the enclosure; (iv) the first fluid chamber and the second fluid chamber separated by a frangible seal; and (v) an access port connected to the enclosure, the port imbedded into the enclosure so as to completely surround the access port, the enclosure further configured such that the frangible seal is broken to uncover the access port.

Abstract: A reconstitution assembly includes: a flexible bag containing a diluent; a drug vial containing a drug; a reconstitution device further comprising: a first sleeve connected to the first container; a second sleeve connected to the second container, the second sleeve being associated with the first sleeve and movable axially with respect thereto from an inactivated position to an activated position; a piercing member positioned in the sleeves, the piercing member providing a fluid pathway between the bag and vial when the sleeves are in the activated position.

Abstract: A system for mixing or reconstituting a drug contained in a first container with a diluent or fluid contained in a second container. The second container has a port docking assembly for engaging the first container. The first container is rotatable and axially slidable within the port docking assembly. The port docking assembly has an actuator to urge a stopper fluidly sealing the first container into the interior of the first container. The port docking assembly further includes a movable plug constructed to fluidly seal the second container in a first, docked position and to provide access to the interior of the second container in a second, activated position, whereby fluid communication between the first and second containers is provided when the first and second containers are in the second, activated position.

Abstract: Method for separating a volume of composite liquid into at least a first component and a second component including centrifuging a separation bag containing a volume of composite liquid and a volume of gas so as to sediment at least a first component and a second component separation bag; displacing a volume of hydraulic fluid against the separation bag to cause a transfer of at least one fraction of the content of the separation bag into at least one component bag connected to the separation bag; determining the volume of hydraulic fluid displaced and determining the volume of the composite liquid or the transferred components from the determined volume of displaced hydraulic fluid.

Abstract: The invention includes compositions of stem and progenitor cells recovered from bone marrow or cord blood containing most of the viable CD34+ cells and substantially depleted of red blood cells resident in the original sample, without any xenobiotic additives to aid cell separation. The invention also includes a system and method for preparing the compositions. The system includes a bag set and a processing device, which utilizes an optical sensor, microcontroller, servo motor, accelerometer, load cell, and battery. The system and method utilize centrifugation to stratify the cells into layers and then separate and transfer the stem cells into a stem cell bag. The processing device's microcontroller receives input from the device's accelerometer, load cell and optical sensor to direct the metering valve in the bag set to open and close to permit the transfer of as many stems cells as possible with as few red cells as possible.

Abstract: A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-?-olefin random copolymer having a crystalline melting point Tm of 135 to 145° C. and a polypropylene (PP) homopolymer having a crystalline melting point Tm of higher than 160° C.

Abstract: In order to provide a medical liquid container which allows for no forgetful failure to open the partition wall and can realize simple and easy sterilization of the liquid medicament bag and thereby decrease the production cost, the present invention provides a medical liquid container having a plurality of communicatably partitioned medical liquid-housing chambers and a discharge reserve chamber having formed therein a discharge port for a liquid medicament, the medical liquid container comprising liquidtightly partitioning portion for liquidtightly separating said liquid medicament-housing chambers from each other, and non-liquidtightly partitioning portion for non-liquidtightly separating between at least one of said liquid medicament-housing chambers and said discharge reserve chamber.

Abstract: An IV infusion bag carrier pack is arranged as a substantially hollow, flexible bag having an interior that is divided into two interior compartments by a flexible, heat permeable divider panel, one interior compartment being arranged to receive and confine an IV fluids bag and the other interior compartment arranged to receive and confine the inflatable pressure cuff member of a blood pressure apparatus, whereby an IV fluids bag contained in the first pocket may be selectively pressurized by inflation of the blood pressure cuff contained in the second pocket whereby selectively controlled infusion delivery of IV fluids contained in the carrier pack apparatus may be continuously maintained irrespective of the relative disposition of the carrier pack apparatus and patient during treatment, extrication and rescue in the field, and transport to a medical facility.

Abstract: The present invention consists of a blood reservoir that incorporates a separate chamber designed to trap condensing water vapor. The blood chamber and the vapor trap are in fluid communication along their top assuring that vacuum applied to the top of the vapor trap is equally applied to the blood chamber. The combination is also structured to prevent condensate water accumulating in the vapor trap chamber from overflowing into the blood chamber as well as provide a structure that allows the end user to empty the water in the vapor trap chamber.

Abstract: A blood tube system for extracorporeal uses, such as dialysis devices, wherein an arterial expansion chamber including a lower region for receiving blood, in which a blood inlet channel terminates, and from which a blood outlet channel extends, and an upper region for receiving air, where a venting channel provided with a venting valve extends from the upper region. The blood tube system includes a central region of the expansion chamber which has considerably reduced cross-sectional dimensions, the blood level being adjustable by means of the venting valve in such a manner that blood/air contact takes place in the central region. The amounts of heparin and EPO needed for a dialysis treatment can thereby be reduced.

Abstract: A pre-assembled medical fluid flow system and method of making same are disclosed. The system includes a first sterilized fluid flow system component, a second sterilized fluid flow system component and a flow path for providing fluid communication therebetween. The flow path includes an isolated portion. An openable closure isolates the isolated portion from the first sterilized fluid system component, and a microorganism filter is disposed between and isolates the isolated portion of the flow path and the second sterilized fluid flow system component. Therefore, fluid from the isolated portion of the flow path must flow through the microorganism filter to reach the second sterilized fluid flow system component.

Abstract: The disclosure relates to a connector for packaging containing medical fluids, in particular infusion or transfusion bags, including a tubular connection part for receiving a spike for the withdrawal of fluid, and having a lower opening on the packaging side and an upper opening on the connection side. A self-sealing membrane, which is pierced by the spike, is located in the connection part. The membrane has an upper, annular section leading into a lower, plate-shaped section, said annular section of the membrane surrounding the spike in a sealing manner, when the latter pierces the plate-shaped section. The membrane acts as a guide for the spike and also reseals the connector, once the spike has been removed.

Abstract: A sealed storage bag of multiple compartment structure, wherein a separated condition of compartments is needed until just before the use, such as an infusion bag of a mixing type of two kinds of liquid or a bag for cooked storage food with flavoring materials. A sealed storage bag comprises a flexible outer bag; an inner bag as a rectangular small compartment having an inner storage space, which is separated, by a film member, from an outer storage space in the outer bag; a filling port for filling contents; and a discharge port for discharging the contents.

Abstract: A welding boat for a pouch has a center part and two prolongations extending therefrom in opposite directions and tapering acutely. The welding boat has an opening for the filling of the pouch with a substance in manufacture and inlets and outlets for the actual use of the pouch. The center part is substantially filled by an opening with a lumen which is as large as possible and preferably circular, and the side edges of the side prolongations contact the opening tangentially.