Pumping Means Patents (Class 604/6.11)
  • Patent number: 10265448
    Abstract: A fluid pump device changeable in diameter is provided. The device has a pump housing which is changeable in diameter and with a rotor which is changeable in diameter. The device has at least one delivery element for fluid, as well as a drive shaft on which the rotor is rotatably mounted. A bearing arrangement is arranged on the drive shaft or its extension, at the distal end of the drive shaft behind the rotor seen from the proximal end of the drive shaft. The bearing arrangement has struts, which elastically brace between a hub of the bearing arrangement and the pump housing.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: April 23, 2019
    Assignee: ECP Entwicklungsgesellschaft MBH
    Inventor: Reiner Liebing
  • Patent number: 10258726
    Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a filtration unit (2), a blood withdrawal line (6), a blood return line (7), an effluent fluid line (13), a pre and/or post-dilution fluid line (15, 25) connected to the blood withdrawal line, and a dialysis fluid line. Pumps (17, 18, 21, 22, 27) act on the fluid lines for regulating the flow of fluid. A control unit (10) is configured to periodically calculate a new value for the patient fluid removal rate to be imposed on an ultrafiltration actuator in order to keep a predefined patient fluid removal rate across a reference time interval irrespective of machine down times.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 16, 2019
    Assignee: Gambro Lundia AB
    Inventor: Dominique Pouchoulin
  • Patent number: 10080827
    Abstract: A blood pump comprising a cartridge, the cartridge comprising a first recess therein, said first recess having a surface, and a flexible diaphragm closing said first recess, the first recess and the flexible diaphragm defining a first pump chamber, said first pump chamber having an inlet and an outlet wherein the flexible diaphragm of the first pump chamber is movable between a first position, separated in use from the surface of the first recess, in which said first pump chamber has a maximum volume, and a second position, substantially adjacent to the surface of the first recess, in which said first pump chamber has a minimum volume a pump driver arranged to interface with the cartridge, said pump driver operable to move the flexible diaphragm of the first pump chamber in a first direction into said first recess to, in use, pump blood from the chamber and to move the flexible diaphragm of the first pump chamber in a second direction away from the first recess to, in use, draw blood into said first pump cham
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: September 25, 2018
    Assignee: Quanta Dialysis Technologies Limited
    Inventor: Clive Henry Buckberry
  • Patent number: 10074446
    Abstract: A medical pump for delivering medicament through an IV line to a patient may provide for awareness of the operator and operator authority limiting access by any individual to particular tasks of procedure review, pump programming, pump loading, patient set up, pump operation, and the like associated with the treatment provided by the medical pump. Identifying the operator allows the assignment of particular authority levels to the operators to ensure proper operation of the medical pump, and/or proper operators have made the necessary review to perform the necessary set up of the medical pump facilitating collaborative healthcare delivery. A record of operator intervention and authority levels may be logged to permit an automatic checklist process by the medical pump. Authentication process and pump operation parameters can be communicated through Near Field Communication (NFC).
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: September 11, 2018
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Todd Sjolander, Mei Zhang
  • Patent number: 9855380
    Abstract: A method for monitoring conveyance of fluid in a device for extracorporeal blood treatment, whereby fluid is conveyed by a peristaltic pump in a fluid system from a low-pressure side to a high-pressure side in that an elastically deformable fluid line positioned between the low-pressure side and the high-pressure side is deformed between a support surface and at least two squeeze elements of a rotor rotating opposite the support surface in such a way that a conveyance volume section is formed between the squeeze elements, whereby a fluid pressure value in the fluid system is detected for the conveyance volume section that is specific to the conveyance volume section, and whereby the detected conveyance-volume-specific fluid pressure value of a conveyance cycle n is compared with the detected conveyance-volume-specific fluid pressure value of a previous conveyance cycle n?x.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: January 2, 2018
    Assignee: B. BRAUN AVITUM AG
    Inventors: Kai-Uwe Ritter, Christian Schleicher
  • Patent number: 9679111
    Abstract: A method of adjusting a patient's undesired hematocrit and/or hemoglobin concentration to a value within a desired range at a predetermined time with an erythropoiesis stimulating agent (ESA) regimen includes obtaining patient parameters required for input into a model for predicting the patient's hematocrit and/or hemoglobin concentration at a predetermined time with a selected ESA administration regimen, the model including iron homeostasis, and employing the patient parameters and an initially selected ESA administration regimen in the model to predict the patient's hematocrit and/or hemoglobin concentration at the predetermined time with the initially selected ESA administration regimen. The method then includes administering ESA to the patient with an ESA administration regimen predicted to adjust the patient's hematocrit and/or hemoglobin concentration to the desired range at the predetermined time. The method can be implemented in a hemodialysis system.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: June 13, 2017
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Doris Helene Fuertinger, Franz Kappel, Peter Kotanko, Nathan W. Levin, Stephan Thijssen
  • Patent number: 9610420
    Abstract: A CPAP device for delivering pressurized, humidified breathable gas for a patient includes a flow generator configured to pressurize a flow of breathable gas. The flow generator includes an air outlet and a removable water container configured to humidify the pressurized breathable gas received from the flow generator. The water container includes an air inlet and an air outlet. The CPAP device further includes a first elastomeric face seal configured to sealingly abut against a substantially flat portion of the water container surrounding the water container air inlet, the first elastomeric face seal being located at an intermediate position between the flow generator air outlet and the water container air inlet when the water container is placed into position to pneumatically communicate with the flow generator.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 4, 2017
    Assignee: ResMed Limited
    Inventors: Perry David Lithgow, Alexander Virr, Duncan Lovel Trevor-Wilson, Andrew Roderick Bath, Michael Thomas Janiak, Dan Kao, Jim Saada
  • Patent number: 9555177
    Abstract: A needle guard is used when suturing the cuff of an attachment ring to the heart. The needle guard is disposed in the attachment ring to prevent other parts of the attachment ring from being punctured by a suturing needle. The needle guard can include one or more grooves to inhibit relative movement between the needle guard and the attachment ring during suturing. The needle guard is removed upon completion of suturing and to allow insertion into attachment ring of an inflow conduit of a heart assist device. An articulated clamp is used to compress the attachment ring into engagement with the inflow conduit. The attachment include an annular rib that grabs the inflow conduit.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: January 31, 2017
    Assignee: THORATEC CORPORATION
    Inventors: Donald Curtis, Alicia Baumberger, John Mark Di Paola, Carine Hoarau, Nathan Harold, Fabian Franco
  • Patent number: 9539389
    Abstract: A flow rate sensor is provided in a wireless, leadless package. The flow rate sensor includes a MEMs sensor coupled to an ASIC and an antenna. The flow rate sensor is powered by radiation received from a control module adjacent the flow rate sensor. The flow rate sensor is placed within a fluid and monitors the flow rate of the fluid. The control module is not in the fluid and receives flow rate data from the flow rate sensor.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: January 10, 2017
    Assignee: STMicroelectronics, Inc.
    Inventors: Nicholas Trombly, Patrick Furlan
  • Patent number: 9494150
    Abstract: The present invention involves, in some embodiments, medical systems for pumping fluid using a medical-grade cartridge configured for use in a reusable fluid medical apparatus to move liquids through the cartridge. The cartridge includes a membrane defining a chamber. The system includes a pressure source able to be placed in pneumatic communication with the chamber to adjust gas pressure therein. The system further includes a processor configured to perform a dry integrity test based on adjustment and measurement of fluid pressures in the chamber in which neither side of the member is exposed to liquid during test to determine whether a fluid leak exists through the membrane.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 15, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr., Geoffrey P. Spencer
  • Patent number: 9488167
    Abstract: The present invention involves, in some embodiments, systems and methods for performing an integrity test on a medical grade cassette that is configured to be used on a medical fluid handling system, wherein the cassette may be disposable and may comprise a membrane therein. The test may be configured to determine an error condition, such as detection of membrane leakage above a threshold value, and may in certain cases be implemented by a medical computer system. In certain cases the integrity test is a dry integrity test and in certain cases, the test is configured to determine a leakage rate of fluid through the membrane.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: November 8, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr., Geoffrey P. Spencer
  • Patent number: 9482216
    Abstract: In various embodiments, a surgical cassette, configured to engage peristaltic pump rollers, may include two or more pump segments between a sheet and a substrate coupled to the sheet. The two or more pump segments on the cassette may produce additional flow (e.g., approximately twice the flow for two segments as opposed to one) than if the cassette had only one pump segment engaging the roller. Further, in some embodiments, the two or more pump segments and rollers on the roller head may be configured to provide a flow profile in which a peak of a pulse from a first pump segment is at least partially out of phase with a peak of a pulse from the second pump segment. The combined resultant flow may then have a flow profile with pulsation amplitudes that are smaller than the individual pump segment pulsation amplitudes.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: November 1, 2016
    Assignee: Alcon Research, Ltd.
    Inventor: Gary P. Sorensen
  • Patent number: 9452285
    Abstract: Aspects of the present invention relate to electroporation devices and methods of using same to effectively facilitate the introduction of a biomolecule into cells of a selected tissue in a body, in particular skin such as intradermic or subcutaneous tissue. In some aspects, the present invention is a skin EP device, which produces a pulse of energy and delivers same to the skin tissue using a skin electrode array and maintains a constant current in the same skin tissue based on user input, including a preset current, and allows the storage and acquisition of current waveform data.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: September 27, 2016
    Assignee: VGX Pharmaceuticals, Inc.
    Inventors: Ruxandra Draghia-Akli, Amir S. Khan
  • Patent number: 9412699
    Abstract: The semiconductor device has insulating films 40, 42 formed over a substrate 10; an interconnection 58 buried in at least a surface side of the insulating films 40, 42; insulating films 60, 62 formed on the insulating film 42 and including a hole-shaped via-hole 60 and a groove-shaped via-hole 66a having a pattern bent at a right angle; and buried conductors 70, 72a buried in the hole-shaped via-hole 60 and the groove-shaped via-hole 66a. A groove-shaped via-hole 66a is formed to have a width which is smaller than a width of the hole-shaped via-hole 66. Defective filling of the buried conductor and the cracking of the inter-layer insulating film can be prevented. Steps on the conductor plug can be reduced. Accordingly, defective contact with the upper interconnection layer and the problems taking place in forming films can be prevented.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: August 9, 2016
    Assignee: SOCIONEXT INC.
    Inventor: Kenichi Watanabe
  • Patent number: 9383288
    Abstract: A monitoring device is arranged to receive a time-dependent measurement signal from a pressure sensor in a fluid containing system, which is associated with a first pulse generator and a second pulse generator. The pressure sensor is arranged in the fluid containing system to detect a first pulse originating from the first pulse generator and a second pulse originating from the second pulse generator. The monitoring device is configured to process the measurement signal to remove the first pulse. In this process, the monitoring device receives the measurement signal, obtains a first pulse profile which is a predicted temporal signal profile of the first pulse, and filters the measurement signal in the time-domain, using the first pulse profile, to essentially eliminate the first pulse while retaining the second pulse. The fluid containing system may include an extracorporeal blood flow circuit and a blood circuit of a human patient.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: July 5, 2016
    Assignee: Gambro Lundia AB
    Inventors: Kristian Solem, Bo Olde
  • Patent number: 9375526
    Abstract: This disclosure relates to vial spiking assemblies and related methods. In certain aspects, the vial spiking assemblies include a vial adapter having a base, a spike extending from a central region of the base, and a sidewall extending from the base and surrounding the spike. The base and the sidewalls partially, define a cavity that is configured to receive at least a portion of the vial. The assemblies also include a spike cover that is removably attached to the spike and that includes a material configured to indicate when the material is contacted with liquid.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: June 28, 2016
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Nigel Wright, Michael John Zang, Tom Monahan, John A. Barron, Douglas Mark Zatezalo
  • Patent number: 9295769
    Abstract: According to one embodiment, a dialysis device is made available that can be implanted at least partially into the body of a patient and comprises a blood chamber, through which the patient's blood can flow, a dialysis chamber for receiving a dialysate, and a hydraulic pump device for compressing the two chambers alternately by means of a hydraulic fluid, wherein both chambers are each equipped with two valves for controlling the inflow and outflow of blood and dialysate, respectively, and wherein both chambers are connected to each other in an area designed as a membrane.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: March 29, 2016
    Assignee: DUALIS MEDTECH GMBH
    Inventors: Wolfgang Schiller, Thomas Schmid, Hiep T Nguyen
  • Patent number: 9272082
    Abstract: A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: March 1, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Jason A. Demers, Michael J. Wilt, Kevin L. Grant, James D. Dale, Brian D. Tracey
  • Patent number: 9222472
    Abstract: The present invention involves, in some embodiments, systems and methods for performing an integrity test on a medical grade cassette that is configured to be used on a medical fluid handling system, wherein the cassette may be disposable and may comprise a membrane therein. The test may be configured to determine an error condition, such as detection of membrane leakage above a threshold value, and may in certain cases be implemented by a medical computer system. In certain cases the integrity test is a dry integrity test and in certain cases, the test is configured to determine a leakage rate of fluid through the membrane.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: December 29, 2015
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr., Geoffrey P. Spencer
  • Patent number: 9211371
    Abstract: A method and apparatus for performing coronary perfusion and cardiac reoxygenation that enables accurate control of oxygen levels in blood used for the coronary circulation. Deoxygenated blood and oxygenated blood are collected and oxygen levels are measured by sensors. The deoxygenated and oxygenated blood is then mixed and the mixed blood is measured by another sensor. The sensors provide data used to provide real-time oxygen level measurement and adjustment for blood supplied for coronary circulation.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: December 15, 2015
    Assignee: Rheoxtech, LLC
    Inventor: Neil J. Thomas
  • Patent number: 9181941
    Abstract: The invention concerns a circuit comprising a bag (111) comprising two flexible films (145, 146) and routing network connectors, and a press (110) comprising a first shell (114) and a second shell (113) clamping the bag to form pipes (104) between the films, the first shell comprising a pinch valve (120) which comprises an actuator (121) comprising a movable member (124) and in register with the moveable member an elastically compressible pad (131) which, when the valve is in an open position, has a resting configuration in which a second face (33) of the pad is concave and locally delimits a shaping channel (118), and, when the valve is in a closed position, has a pinching configuration in which the second face (133) is convex, with the pipe and the pad sandwiched between a shaping channel (116) and the moveable member.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: November 10, 2015
    Assignee: EMD Millipore Corporation
    Inventors: Sebastien Cirou, Jean-Louis Weissenbach
  • Patent number: 9168333
    Abstract: A dialysis system includes a dialysis machine having a pump actuator, a valve actuator and a sorbent device, and a disposable cassette including (i) a housing having a dialyzer inlet port, a dialyzer outlet port, a pump portion configured to operate with the pump actuator, a valve portion configured to operate with the valve actuator, a venous port, and an arterial port, (ii) at least one dialyzer in fluid communication with the housing, the at least one dialyzer including a dialysate inlet, and a dialysate outlet; (iii) an arterial line for connecting to a patient, the arterial line connected to and extending externally from the arterial port of the housing; (iv) a venous line for connecting to a patient, the venous line connected to and extending externally from the venous port of the housing; and (v) first and second dialysate fluid connections in fluid communication with the sorbent device.
    Type: Grant
    Filed: October 10, 2014
    Date of Patent: October 27, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din
  • Patent number: 9155824
    Abstract: A concentrate container for preparing a medical fluid, preferably for preparing a dialysis solution, is provided, the concentrate container including at least two concentrate compartments, wherein at least one of the concentrate compartments has a medical fluid outlet, and at least one of the concentrate compartments has a diluent inlet. Further, systems for preparing a medical fluid and a method for preparing a medical fluid are described.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: October 13, 2015
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventors: Thierry Eyrard, Philippe Laffay, Benoît Luaire
  • Patent number: 9067003
    Abstract: A method for providing a negative pressure wherein a pump is cycled on and off to achieve a target negative pressure, which is set slightly lower than the therapeutic negative pressure. A device determines the actual pressure by averaging samples which may occur at a different rate than the pump cycle.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: June 30, 2015
    Assignee: Kalypto Medical, Inc.
    Inventors: John Buan, Richard Willems
  • Patent number: 9011360
    Abstract: A liquid collection bag is used as a part of an extracorporeal circuit and is connected via a tube to a storage container containing a priming solution. The collection container collects the priming solution from the storage container by a pressure differential between the pressure inside the collection container and the pressure inside the storage container. The liquid collection container is a flexible bag body having a partition part dividing the inside of the bag body into a first space and a second space. In addition, a communication part communicates the first space with the second space.
    Type: Grant
    Filed: August 12, 2013
    Date of Patent: April 21, 2015
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Norikazu Ishida, Hidetaka Nakayama
  • Patent number: 9005152
    Abstract: A dialysis system includes a fresh dialysis fluid membrane pump; a spent dialysis fluid membrane pump; a first balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; a second balance chamber having a fresh dialysis fluid compartment connected fluidly to the fresh dialysis fluid membrane pump and a spent dialysis fluid compartment connected fluidly to the spent dialysis fluid membrane pump; and a dialysis fluid cassette, wherein at least one of the fresh dialysis fluid membrane pump, the spent dialysis fluid membrane pump, the first balance chamber and the second balance chamber includes a fluid receiving portion provided in the dialysis fluid cassette.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: April 14, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din
  • Patent number: 9005153
    Abstract: The invention further relates to an apparatus and method for monitoring a peristaltic hose pump, in particular a peristaltic hose pump of an extracorporeal blood treatment device. The power consumed by the pump and/or the pressure in the tubing segment upstream or downstream of the pump is/are measured during operation of the pump and test signals I1(t), I2(t) which are associated with the individual displacement members are determined. The power or pressure signals associated with the individual displacement members significantly differ from each other during abnormal operation of the hose pump, but no significant differences can be recognized during normal operation of the pump.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: April 14, 2015
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Pascal Kopperschmidt, Reiner Spickermann
  • Patent number: 8998836
    Abstract: A method of pneumatically operating a dialysis system includes (i) pumping air in a first valve state from a pneumatic pump to operate a component of the dialysis system, and (ii) recirculating air in a second valve state by pumping air from an outlet of the pneumatic pump to an inlet of the pneumatic pump to minimize at least one of a noise pitch or noise amplitude when switching from the second valve state to the first valve state.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: April 7, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Paul R. Chapman, Robert W. Childers, Gideon Hecht, Anders Wellings
  • Patent number: 8989906
    Abstract: A method is provided for regulating fluid pump pressures by detecting an elevation differential between a fluid flow control device and the distal end of a fluid line in communication with the fluid flow control device. A fluid flow control device, for instance a peritoneal dialysis device, is at a first height, a distal end of a fluid line is at a second height, and a valved outlet, when open, affords communication between the fluid flow control device and the distal end of the fluid line. The elevation differential is correlatable with a pressure measurable during a calibration procedure provided as a part of the methodology.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: March 24, 2015
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr.
  • Publication number: 20150080782
    Abstract: An access disconnection system includes a venous line, an arterial line, a first electrode coupled to (i) the arterial line, (ii) a patient, or (iii) a cardiac catheter assembly; and a second electrode coupled to (i) the venous line, or (ii) the cardiac catheter assembly. The access disconnection system further includes electronic circuitry communicating electrically with the first second electrode to sense an electrical heartbeat signal generated by the patient. The electronic circuitry is configured to send a disconnection output indicative of a change in the electrical signal sufficient to expect that an access disconnection of the venous line has occurred.
    Type: Application
    Filed: November 24, 2014
    Publication date: March 19, 2015
    Inventors: Rodolfo Roger, Robert Childers, Thomas D. Kelly
  • Patent number: 8979788
    Abstract: A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: March 17, 2015
    Assignee: DEKA Products Limited Partnership
    Inventors: Jason A. Demers, Larry B. Gray, James D. Dale, N. Christopher Perry, David E. Altobelli
  • Patent number: 8968232
    Abstract: Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: March 3, 2015
    Assignee: DEKA Products Limited Partnership
    Inventors: Dean Kamen, Jason A. Demers, David E. Altobelli, Larry B. Gray, N. Christopher Perry, Brian Tracey, James D. Dale, Dirk A. van der Merwe, Kingston Owens
  • Patent number: 8961444
    Abstract: A dialysis fluid pressure manifold system includes a plurality of pump and valve chambers controlling a flow of dialysis fluid; a header including a plurality of pneumatic passageways, each passageway in pneumatic communication with one of the pump or valve chambers; a plurality of electrically actuated pneumatic valves; and a plate defining a plurality of pneumatic apertures, each pneumatic aperture in pneumatic communication with one of the plurality of electrically actuated pneumatic valves, the plate providing the apertures each with an o-ring seal for airtight connection with the pneumatic passageways of the header.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: February 24, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Paul R. Chapman, Robert W. Childers, Gideon Hecht, Anders Wellings
  • Patent number: 8956317
    Abstract: In a single needle extracorporeal blood treatment apparatus, an ultrafiltration pump (10) performs a pure ultrafiltration of ultrafiltrate from an hemofilter (4). The blood may be continuously circulated through the hemofilter using a first pump (5), which alternates an higher flow rate during the arterial phase and a lower flow rate during the venous phase, and a second pump (6) which is maintained at a flow rate intermediate between said higher and lower flow rate. The apparatus may be used for treatment of Congestive Heart Failure.
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: February 17, 2015
    Assignee: Gambro Lundia AB
    Inventor: Hiram Rada
  • Patent number: 8951219
    Abstract: A method includes initiating a blood fluid removal session of a patient; monitoring an indicator of tissue fluid volume of the patient, or a portion thereof, during the blood fluid removal session; monitoring an indicator of blood fluid volume of the patient during the blood fluid removal session; determining whether a ratio of the indicator of tissue fluid volume to indicator of blood fluid volume is outside of a predetermined range; and altering the rate of fluid removal during the blood fluid removal session if the ratio is determined to be outside of the predetermined range. A blood fluid removal system may be configured to carry out the method.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: February 10, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, Suping Lyu, Manda R. VenKalesh, Bryant Pudil
  • Patent number: 8945037
    Abstract: A blood purification apparatus has a dialyzer (1), an arterial blood circuit (2) with a blood pump 4, a venous blood circuit 3, a dialysate introduction line L1, a dialysate discharge line L2, a substitution line L3, and a substitution pump 9 that supplies the dialysate flowing in the substitution line L3 to the arterial blood circuit 2. A control device (11) estimates or measures the concentration of blood in a dilution channel section A. The control device (11) controls the volume of dialysate supplied by the substitution pump 9 on the basis of the estimated or measured blood concentration.
    Type: Grant
    Filed: September 24, 2012
    Date of Patent: February 3, 2015
    Assignee: Nikkiso Company Limited
    Inventors: Shinya Hasegawa, Masahiro Toyoda
  • Patent number: 8945036
    Abstract: The present invention includes a comprehensive replacement fluid system and method for the delivery of regional citrate anticoagulation (RCA) to extracorporeal blood circuits, wherein the system may include an online clearance monitor (OCM) and a circuit effluent online sensor system (OSS) for the continuous determination of patient plasma content of ultrafilterable solutes.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: February 3, 2015
    Assignee: Henry Ford Health System
    Inventors: Balazs Szamosfalvi, Stanley Frinak, Jerry Yee
  • Patent number: 8939926
    Abstract: A system and method for removing gas bubbles from blood during circulatory assist procedures. An active filter apparatus forces the bubbles to the center of the system where they are removed from the blood before the blood exits the filter.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: January 27, 2015
    Assignee: Indian Wells Medical, Inc.
    Inventors: David W. Wieting, Jay A. Lenker
  • Patent number: 8932032
    Abstract: A process fluid pump can include a pump chamber, an inlet valve, and an outlet valve. Diaphragm regions can define at least a portion of each of the pump chamber, the inlet valve, and the outlet valve. The diaphragm regions can each have an actuation region with a surface that is convexly shaped when the formed actuation region is in a natural unstressed first state, and each formed actuation region can be actuated by a motive fluid to transition to a second state in which the surface is non-convexly shaped.
    Type: Grant
    Filed: May 15, 2012
    Date of Patent: January 13, 2015
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventor: Troy J. Orr
  • Patent number: 8926551
    Abstract: Patients suffering from acute renal failure must be diagnosed and treated quickly so that a physician can confidently prescribe either peritoneal dialysis or hemodialysis. In one way of quickly treating the patients, software is used to calculate a suitable peritoneal dialysis prescription without regard to how short or how long a dialysis cycle is used, and without regard to a total dialysate fluid volume for a therapy. For patients with suitable peritoneal membrane transport properties, the software program suggests that, at least over a short period of time, unexpectedly high ultrafiltrate volumes and high clearances may be achieved.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: January 6, 2015
    Assignees: Baxter Healthcare Inc., Baxter Healthcare S.A.
    Inventors: Ying-Cheng Lo, Alp Akonur, Yuanpang S. Ding
  • Patent number: 8926835
    Abstract: A dialysis machine that includes a valve member having a deformable area configured to deform outwardly away when pressurized fluid is introduced into the valve member. The valve member is configured so that, when a dialysis fluid cassette is disposed in a cassette compartment of the dialysis machine and pressurized fluid is introduced into the valve member, the deformable area obstructs a fluid channel of the dialysis fluid cassette to control dialysis fluid flow therethrough.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: January 6, 2015
    Assignee: Fresenius Medical Care Deustschland GmbH
    Inventors: Josef Beden, Juergen Braun, Hans-Peter Schneider
  • Patent number: 8926542
    Abstract: A method includes monitoring an indicator of fluid volume of a patient via a sensor device, and setting an initial fluid volume removal prescription for a blood fluid removal session based on the monitored indicator of fluid volume. The method may further include transmitting data regarding the indicator of fluid volume from the implantable sensor device to fluid removal device. In some embodiments, the fluid removal device sets or calculated the initial fluid volume removal prescription based on the data received from the implantable sensor. The indicator of fluid volume may be an indicator of tissue fluid volume or an indicator of blood fluid volume.
    Type: Grant
    Filed: March 20, 2012
    Date of Patent: January 6, 2015
    Assignee: Medtronic, Inc.
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, VenKatesh R. Manda, Byant Pudil
  • Patent number: 8926544
    Abstract: A dialysis system includes: a blood filter; a dialysate pump connected to a dialysate portion of the blood filter; a blood pump connected to a blood portion of the blood filter, the blood pump including a diaphragm that is moved in cycles to pump the blood, the cycles having a flow period and a no-flow period; a patient access device in fluid communication with the blood portion of the blood filter, the no-flow period having a first characteristic of a property when the patient access device is lodged in a patient and a second characteristic of the property when the patient access device is dislodged from the patient; and a logic implementer configured to determine that the patient access device has been dislodged from the patient when the second characteristic of the parameter is detected.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: January 6, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Michael Hogard
  • Patent number: 8920356
    Abstract: A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethylenedioxythiophene, poly(p-phenylene vinylene) and mixtures thereof.
    Type: Grant
    Filed: June 30, 2011
    Date of Patent: December 30, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: Sherwin Shang, Ramesh Wariar, Angel Lasso, George Lamberson, Dan F. Marcquenski, Jr., Jan Jensen, David Kuhn, Raf Castellanos
  • Patent number: 8915876
    Abstract: The present invention relates to a method for removing blood from an extracorporeal blood circuit and/or a functional device, each connectable or connected with a blood treatment apparatus for the purpose of blood treatment of a patient. The blood treatment apparatus of the method comprises or is connected with at least one extracorporeal blood circuit with a line having interior portions, the extracorporeal blood circuit comprising at least one arterial line section and at least one venous line section, wherein a first section of the arterial line section is configured to be connected with a second section of the venous line section, and further comprises at least one blood pump for conveying blood within the line interior portions. The method includes the step of operating the blood pump in a second conveying direction which is opposite to a first customary conveying direction. It further relates to corresponding apparatuses.
    Type: Grant
    Filed: July 27, 2012
    Date of Patent: December 23, 2014
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventors: Soeren Gronau, Juergen Haecker, Ralf Mueller, Manfred Weis, Stefan Kreber, Martin Thys
  • Patent number: 8911390
    Abstract: The present invention concerns a multipart fluid system for use in CRRT, wherein the multipart fluid system comprises an anticoagulation fluid and at least one fluid from the group consisting of a dialysis fluid and an infusion fluid. According to the invention the anticoagulation fluid comprises at least 8 mM citrate, and the dialysis fluid and/or infusion fluid comprises 2-8 mM citrate and 1-5 mM total calcium. The present invention further concerns a system for regional citrate anticoagulation in an extracorporeal blood circuit.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: December 16, 2014
    Assignee: Gambro Lundia AB
    Inventor: Jan Sternby
  • Patent number: 8905960
    Abstract: A device for the filtration of a complex fluid composition such as blood, includes a base (12) with a bottom (18), a top (14) with a bottom (30), and a membrane (16) that is arranged between the base and the top so as to define a low chamber C1 and a high chamber C2, with an input tap (26) of the complex composition that is to be filtered emptying into the low chamber C1, an output tap (28) of the retentate with elements for adjusting the flow rate emptying into this same low chamber C1, and an output tap (36, 36-1) of the high chamber C2, whereby this output tap (36, 36-1) of the permeate is subjected to negative pressure.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: December 9, 2014
    Assignee: Direction et Priorites
    Inventors: Francis Gadrat, Bertrand Chastenet
  • Patent number: 8906300
    Abstract: A blood oxygenator includes an integral pneumatic pump disposed substantially within a housing thereof, an inlet blood flow redirector, and an outflow blood collector. An atrium provided at an inlet of the oxygenator promotes even delivery of blood to the oxygenator. In use, the oxygenator provides an even dispersion of blood therethrough, establishing even perfusion and reducing areas of stagnant blood flow.
    Type: Grant
    Filed: August 13, 2012
    Date of Patent: December 9, 2014
    Assignee: The University of Kentucky Research Foundation
    Inventors: Dongfang Wang, Joseph B. Zwischenberger
  • Patent number: 8900174
    Abstract: A method for operating a dialysis cassette including a flexible membrane that covers a pump chamber includes applying a vacuum about a piston head and sucking the flexible membrane of the dialysis cassette onto the piston head; mechanically retracting the piston head along with the vacuum applied membrane away from the dialysis cassette to draw fluid into the pump chamber; mechanically extending the piston head and the flexible membrane into the pump chamber to expel fluid from the pump chamber through a flow path; and directly sensing a pressure of the fluid flowing through the flow path at a location of the dialysis cassette adjacent to the pump chamber.
    Type: Grant
    Filed: December 5, 2011
    Date of Patent: December 2, 2014
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventor: Robert W. Childers
  • Patent number: 8894600
    Abstract: A hemodialysis system includes an on-line dialysate generator; a dialysate pump actuator configured to pump dialysate generated by the generator to a dialyzer; a conductivity sensor located adjacent to a temperature sensor upstream of the dialyzer; a blood pump actuator; an air detector; and a disposable cassette configured to carry dialysate pumped by the dialysate pump actuator, the disposable cassette including a conductivity sensor portion and a temperature sensor portion located to operate with the conductivity sensor and the temperature sensor, respectively, the disposable cassette further configured to carry blood pumped by the blood pump actuator and to provide an air detection portion located to operate with the air detector.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: November 25, 2014
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Thomas Kelly, Robert W. Childers, Don Busby, Rodolfo Roger, Waleed Mutasem El Sayyid, Shahid Din