Pumping Means Patents (Class 604/6.11)
  • Patent number: 11918721
    Abstract: An example peritoneal dialysis system is disclosed. The example peritoneal dialysis system includes at least one pump and a memory device configured to store therapy prescriptions including a low ultrafiltration (“UF”) therapy prescription, a first standard UF therapy prescription with a longer duration and a lower dextrose concentration, and a second standard UF therapy prescription with a shorter duration and a higher dextrose concentration. The memory device also stores a schedule indicative as to which of the therapy prescriptions are to be performed on specified dates. The system further includes a logic implementer configured to determine or identify a current date, use the schedule stored in the memory device to select the therapy prescription based on the current date, and control the at least one pump based on the selected therapy prescription to perform a peritoneal dialysis therapy.
    Type: Grant
    Filed: April 22, 2022
    Date of Patent: March 5, 2024
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Alex Anping Yu, James Grayson, Robert W. Childers
  • Patent number: 11904078
    Abstract: A portable hemodialysis system is provided including a dialyzer, a closed loop blood flow path which transports blood from a patient through the dialyzer and back to the patient, and a closed loop dialysate flow path which transports dialysate through the dialyzer. Preferably, the hemodialysis system includes a sorbent filter in the dialysate flow path. Furthermore, the hemodialysis machine includes a blood pump, and a pair of dialysate pumps. A processor controls the flow of blood through the blood flow path, and the processor controls the flow of dialysate through the dialysate flow path. In addition, the processor stores a patient treatment plan wherein the flow rate of the dialysate through the dialysate flow path reduces throughout the patient's treatment to maximize the amount of urea removed by the sorbent filter.
    Type: Grant
    Filed: May 28, 2021
    Date of Patent: February 20, 2024
    Assignee: DIALITY INC.
    Inventors: Brandon Borillo, Tzu Tung Chen, Clayton Poppe
  • Patent number: 11896752
    Abstract: A dialysis machine configured to carry out a method and a method for draining an extracorporeal fluid circuit utilizing a dialysis machine, wherein the dialysis machine is connected to a dialyzer and said extracorporeal fluid circuit, said extracorporeal fluid circuit comprising an arterial line connectable to a patient, for drawing blood from the patient and a venous line connectable to the patient for returning blood to the patient, the method comprising: after treatment termination from said extracorporeal fluid circuit draining remaining fluid from said extracorporeal fluid circuit through the dialyzer.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: February 13, 2024
    Assignee: Gambro Lundia AB
    Inventors: Sture Hobro, Roger Nilsson, Olof Jansson, Björn Ericson
  • Patent number: 11890399
    Abstract: Systems and methods are provided for separating blood into two or more components for collection of red blood cells, plasma, or both red blood cells and plasma. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit, with the blood being separated into its constituents by the centrifugal separator. Separated plasma may be collected following separation by the centrifugal separator or may first be conveyed from the centrifugal separator into the spinning membrane separator drive unit to separate cellular blood components from the plasma prior to collection of the filtered plasma. The cellular blood components filtered from the plasma may be retained in the circuit as a waste product or may be flushed out of the circuit to a recipient.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: February 6, 2024
    Assignee: Fenwal, Inc.
    Inventors: Benjamin E. Kusters, Kyungyoon Min
  • Patent number: 11883642
    Abstract: A blood pump system and methods for the use and operation of such a blood system is described, wherein the blood pump system includes an implantable pump and an implantable flow measurement device. A processing device receives indications of a number of pump parameters such as pump voltage, pump current and pump speed. Flow rate is determined based on the pump parameters, and this determined flow rate is compared to the actual flow rate as measured by the flow measurement device. In certain embodiments, the flow measurement device may be periodically energized to make the comparison, then powered off to reduce power consumption. The time period in which the flow measurement device is powered off is based on the difference between the determined and the actual flow rates.
    Type: Grant
    Filed: May 21, 2018
    Date of Patent: January 30, 2024
    Assignee: ReliantHeart, Inc.
    Inventor: Gino F. Morello
  • Patent number: 11872383
    Abstract: The present invention discloses a flexible shaft structure insulating wear particles by perfusion, which includes a flexible transmission shaft, a proximal holder is provided at one end of the flexible transmission shaft, a distal holder is provided at the other end of the flexible transmission shaft, a constraint insulator and an outer sheath tube are provided outside the flexible transmission shaft, and the constraint insulator sequentially includes an inner constraint layer, an insulation layer and an outer constraint layer from inside to outside; a perfusion inflow annular cavity is formed between the outer constraint layer and the outer sheath tube and between the outer constraint layer and the insulation layer, respectively, and a static sealed inner cavity is formed between the inner constraint layer and the insulation layer and between the inner constraint layer and the flexible transmission shaft, respectively; the proximal holder is provided with a perfusion inlet pipeline communicated with the perf
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: January 16, 2024
    Assignee: FORQALY MEDICAL(SHANGHAI) CO., LTD.
    Inventors: Qiwen Zheng, Zhirong Tang
  • Patent number: 11806460
    Abstract: A method includes, after an extracorporeal blood treatment, connecting a fluid source to an access line that is connected to a patient, and delivering a fluid from the fluid source to the access line to infuse blood from the access line to the patient, wherein the fluid delivered to the access line has a temperature from about 30 degrees Celsius to about 38 degrees Celsius.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: November 7, 2023
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: David Yuds, Samiullah K. Durrani, Martin Joseph Crnkovich
  • Patent number: 11802551
    Abstract: Disclosed is a dual-stage fluidics system that has reduced pulsation. This system uses inexpensive peristaltic pumps and two reservoirs that dampen pulsations in pressure. Peristaltic pumps are used as air pressure pumps and sheath fluid pumps that are placed between the two pressurized reservoirs and isolate the two reservoirs. Since the two reservoirs are maintained at a substantially even pressure, pulsations are reduced so that the peristaltic pumps essentially provide air flow and sheath fluid flow as needed.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: October 31, 2023
    Assignee: Life Technologies Corporation
    Inventors: Daniel N Fox, Nathan M Fox
  • Patent number: 11783503
    Abstract: A method for estimating extracorporeal blood volume in at least a portion of a physical sample. A feature is extracted from an image of the physical sample. The extracorporeal blood volume in the portion of the physical sample is estimated. The estimation may be based on the extracted feature and at least one of the estimated distance and the estimated angle between a capture origin of the image and the portion of the physical sample based on a returned signal transmitted from a distance sensor. The estimated extracorporeal blood volume may be displayed on a display, such an augmented reality overlay in which the image of the portion of the physical sample is displayed with at least one of the estimated extracorporeal blood volume or a sample counter. The sample counter may be indexed for the physical sample after estimating the extracorporeal blood volume.
    Type: Grant
    Filed: December 20, 2021
    Date of Patent: October 10, 2023
    Assignee: Gauss Surgical Inc.
    Inventors: Siddarth Satish, Kevin J. Miller, Ali Zandifar
  • Patent number: 11771407
    Abstract: A probe having a contact force sensor is inserted into a cardiac chamber and an image of the blood pool is generated. A portion of the blood pool is removed from the image to retain a remaining portion of the blood pool. A determination is made that the distal segment of the probe is within the remaining portion of the blood pool, and responsively to the determination the contact force sensor is manually zeroed.
    Type: Grant
    Filed: May 8, 2019
    Date of Patent: October 3, 2023
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Natan Sharon Katz, Aharon Turgeman, Doron Moshe Ludwin, Ronen Krupnik
  • Patent number: 11759557
    Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: September 19, 2023
    Assignee: Mozarc Medical US LLC
    Inventors: Martin Gerber, John Burnes, SuPing Lyu, Venkatesh R. Manda, Bryant Pudil
  • Patent number: 11596725
    Abstract: The invention relates to a device for extracorporeal blood treatment, comprising a blood treatment unit 1 that comprises at least one compartment 4. The invention further relates to a method for determining a hemodynamic parameter during an extracorporeal blood treatment by means of an extracorporeal blood treatment device. In order to determine the hemodynamic parameter, the conveying direction of the blood pump 10 is reversed from a “normal” blood flow to a “reversed” blood flow. In practice, it has been found that reversing the conveying direction of the blood pump for a measurement for determining a hemodynamic parameter carries the risk of blood clots reaching the patient, despite the dialyser holding back blood clots. The blood treatment device comprises an input unit 23 for inputting a time interval which can be specified by the user, taking into account the patient-specific and system-specific factors.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: March 7, 2023
    Assignee: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH
    Inventor: Andreas Maierhofer
  • Patent number: 11554202
    Abstract: Microbubbles detached from a blood circuit and a blood purification unit are discharged with the use of a backflow generated at the instant that a roller of a blood pump releases a squeezable tube. In a normal rotation step, a region filled with a priming solution after a priming step is closed by a closing unit, and a rotor of a blood pump is rotated normally until a roller of the blood pump releases a squeezable tube to generate a backflow. After the backflow is generated at the release of the squeezable tube by the roller of the blood pump, bubbles are moved by reversely rotating the rotor while disabling the closing by the closing unit. Thus, the bubbles are discharged through a discharge unit.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: January 17, 2023
    Assignee: Nikkiso Company Limited
    Inventors: Shunichi Koda, Shunsuke Kawamura, Shingo Okamoto
  • Patent number: 11541160
    Abstract: A perfusion system includes a fluid reservoir configured to hold a portion of fluid, the portion of fluid having a volume, the fluid reservoir having a total capacity that is greater than the volume; an imaging device, the imaging device configured to obtain image data corresponding to the fluid reservoir; and a controller. The controller is configured to receive the image data from the imaging device; determine the volume based on the image data; and facilitate control, in response to at least one of a user input and the determined volume of the portion of fluid, of an operating parameter corresponding to the fluid reservoir to facilitate changing or maintaining the volume of the portion of the fluid.
    Type: Grant
    Filed: November 22, 2018
    Date of Patent: January 3, 2023
    Assignee: LivaNova Deutschland GmbH
    Inventors: Olivier Wolfgramm, Michael Bonczar, Marco Zanasi
  • Patent number: 11529449
    Abstract: In examples described herein, a system includes an elongate member configured to be introduced into vasculature of a patient. The elongate member includes a pressure sensor configured to generate a pressure signal indicative of pressure in the vasculature adjacent the needle. The system includes processing circuitry configured to receive the pressure signal from the pressure sensor, detect, based on the pressure signal, dislodgment of the elongate member from the vasculature, and generate an output in response to detecting the dislodgment of the elongate member from the vasculature.
    Type: Grant
    Filed: February 4, 2020
    Date of Patent: December 20, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Daniel Bloomberg, VenKatesh Manda
  • Patent number: 11511040
    Abstract: A fluid control device includes an interface to a remote fluid monitoring sensor that detects fluid flow in a patient. In some embodiments, a processor within the fluid delivery device is programmed to adjust the delivery or withdrawal of fluids based on the fluid flow signals provided by the sensor. In some embodiments, the fluid control device can display and/or record fluid flow signals thereby acting as a hemodynamic monitor.
    Type: Grant
    Filed: May 22, 2020
    Date of Patent: November 29, 2022
    Assignee: 1929803 Ontario Corp.
    Inventors: Joseph Eibl, Jon-Emile Kenny
  • Patent number: 11478615
    Abstract: A catheter securement device with integrated intra-luminal electro-conduction, and external tamper sensitivity, for tamper or movement detection. The catheter securement device accordingly can detect movement or tampering of an inserted catheter, which will allow a healthcare provider to take action to prevent movement or removal of the catheter from a patient.
    Type: Grant
    Filed: May 20, 2020
    Date of Patent: October 25, 2022
    Assignee: NOVUM VASCULAR, LLC
    Inventor: Terrell Friedrich
  • Patent number: 11452802
    Abstract: A negative-balanced isolated pelvic perfusion method, in which a drug is administered into the closed pelvis while keeping the volume of suction from the vein larger than that of injection into the artery, does not require allogeneic blood transfusion. A perfusion device is for recovering a liquid containing a drug and/or blood from a tube connecting to the inferior vena cava and for injecting the liquid obtained into a tube connecting to the artery, provided with a unit for closing the inside of the pelvis by including a unit for blocking the artery from the heart to the pelvis, a unit for blocking the inferior vena cava from the pelvis to the heart, and a unit for blocking a blood flow from the pelvis to the lower limbs. The perfusion device is provided with a pelvic perfusion unit equipped with a reservoir, an autotransfusion unit, and a dialysis unit.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: September 27, 2022
    Assignees: KOSEI ADVANCE CO., LTD.
    Inventor: Satoru Murata
  • Patent number: 11298525
    Abstract: Systems and methods are described herein relating to an intracardiac blood pump system comprising a pump, an elongate multi-lumen catheter, a compartment connected to the catheter, a first lumen, a conduit and a filter disposed within the conduit. At least one electronic element is located within the compartment. The conduit extends through an interface between the compartment and the catheter. The conduit is configured to allow gas to penetrate from a first end of the conduit through the first opening of the compartment to a second end of the conduit. The second end of the conduit is in fluid communication with a central lumen of the elongate multi-lumen catheter. The filter is configured to prevent egress of liquid from the multi-lumen catheter into the compartment after allowing flow of gas from the first end of the conduit through the second end of the conduit and into the multi-lumen catheter.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: April 12, 2022
    Assignee: ABIOMED, INC.
    Inventor: Emilia Jahangir
  • Patent number: 11253638
    Abstract: A device and method are used for monitoring an extracorporeal blood treatment device, such as a dialysis machine, which includes an extracorporeal blood circuit having an arterial blood line with an arterial patient port and/or at least one venous blood line with a venous patient port, and a dialysis fluid system which has a dialysis fluid supply line and a dialysis fluid drain line. The monitoring device selects and senses a measured value during operation of the extracorporeal blood treatment device which is suitable for monitoring the blood treatment device to compare a time-related actual course of the measured value with a target course of the measured value stored in a memory, and to determine that there is a defect if, at least in sections, the actual course of the measured value deviates from the target course by more than a defined tolerance.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: February 22, 2022
    Assignee: B. BRAUN AVITUM AG
    Inventors: Jennifer Steger, Peter Bruchhäuser, Günter Nissen
  • Patent number: 11241572
    Abstract: Method and systems control a rotational speed of a blood pump during ventricular diastole. A method includes controlling a blood pump in accordance with a first segment operational mode. A controller monitors the blood flow rate through the blood pump. The controller determines, based on the blood flow rate, whether continued controlling of the blood pump per the first segment operational mode would result in the blood flow rate through the blood pump being less than a target minimum blood flow rate. In response to a determination that continued controlling of the blood pump per the first segment operational mode would result in the blood flow rate through the blood pump being less than the target minimum blood flow rate, the controller controls the rotational speed of the blood pump so that the blood flow rate through the blood pump is approximate to the target minimum blood flow rate.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: February 8, 2022
    Assignee: TC1 LLC
    Inventors: Charles Dague, Dan Harjes
  • Patent number: 11179506
    Abstract: An apparatus is including a negative pressure wound therapy pump including a pump housing; and a negative pressure wound therapy canister attached to and readily removable from the pump housing; the canister including a flexible conduit; the canister operable to receive suction generated by the pump; the flexible conduit sized, shaped, and located to interface with the pump housing of the pump such that suction produced by the pump is transmitted to the canister via the flexible conduit.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: November 23, 2021
    Assignee: Cork Medical, LLC
    Inventors: Aaron Barr, John Anthony Lamper, Philip Leighton Ramge, Elliott Conrad Lasher
  • Patent number: 11123464
    Abstract: The disclosure relates to a dialysis machine that comprises a dialyzer, a fluid source, a first line connected to the fluid source, and a container containing bicarbonate. The container connects to the first line and the fluid flows from the fluid source, through the first line, to the container. The dialysis machine further includes a second line connected to the container, a flow rate sensor connected to at least one of the lines, a pressure sensor configured for detecting fluid pressure of the container, a display, and a data processing apparatus. The data processing apparatus is configured to receive signals from the flow rate sensor and the pressure sensor. The data processing apparatus is configured to calculate a size of the container based on the received signals.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: September 21, 2021
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: David Yuds, Martin Joseph Crnkovich, Ken Chhi
  • Patent number: 10857272
    Abstract: A fluid pump device changeable in diameter is provided. The device has a pump housing which is changeable in diameter and with a rotor which is changeable in diameter. The device has at least one delivery element for fluid, as well as a drive shaft on which the rotor is rotatably mounted. A bearing arrangement is arranged on the drive shaft or its extension, at the distal end of the drive shaft behind the rotor seen from the proximal end of the drive shaft. The bearing arrangement has struts, which elastically brace between a hub of the bearing arrangement and the pump housing.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 8, 2020
    Assignee: ECP ENTWICKLUNGSGESELLSCHAFT MBH
    Inventor: Reiner Liebing
  • Patent number: 10856745
    Abstract: A blood pump including a housing having an inlet element, the inlet element including a distal portion coupled to the housing and a proximal portion sized to be received within at least a portion of a heart of a patient and a rotor configured to rotate within the housing and impel blood from the heart. At least one pressure sensor is coupled to the proximal portion of the inlet element.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: December 8, 2020
    Assignee: HeartWare, Inc.
    Inventor: Fernando Casas
  • Patent number: 10835658
    Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: November 17, 2020
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel J. Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
  • Patent number: 10835653
    Abstract: A fluid pump device changeable in diameter is provided. The device has a pump housing which is changeable in diameter and with a rotor which is changeable in diameter. The device has at least one delivery element for fluid, as well as a drive shaft on which the rotor is rotatably mounted. A bearing arrangement is arranged on the drive shaft or its extension, at the distal end of the drive shaft behind the rotor seen from the proximal end of the drive shaft. The bearing arrangement has struts, which elastically brace between a hub of the bearing arrangement and the pump housing.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: November 17, 2020
    Assignee: ECP ENTWICKLUNGSESELLSCHAFT MBH
    Inventor: Reiner Liebing
  • Patent number: 10772998
    Abstract: A device for draining bodily fluids is described herein which generally may comprise an elongate body defining one or more lumens configured to receive a bodily fluid from a cavity, e.g., bladder, of a patient body. The one or more lumens are in fluid communication with a reservoir which may receive the bodily fluid. A pumping mechanism may be used to urge the bodily fluid through the one or more lumens, where the pumping mechanism is configured to maintain an open space within the one or more lumens such that outflow of the bodily fluid through the one or more lumens remains unobstructed such that a negative pressure buildup in the cavity is inhibited. The device may also include a vent or valve mechanism in communication with the elongate body to allow air to enter or exit the one or more lumens.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: September 15, 2020
    Assignee: Potrero Medical, Inc.
    Inventors: Evan S. Luxon, Marcie Hamilton, Daniel R. Burnett, Mark Ziegler
  • Patent number: 10731652
    Abstract: A rotary blood pump includes a casing defining a pumping chamber. The pumping chamber has a blood inlet and a tangential blood outlet. One or more motor stators are provided outside of the pumping chamber. A rotatable impeller is within the pumping chamber and is adapted to cause blood entering the pumping chamber to move to the blood outlet. The impeller has one or more magnetic regions. The impeller is radially constrained in rotation by magnetic coupling to one or more motor stators and is axially constrained in rotation by one or more hydrodynamic thrust bearing surfaces on the impeller.
    Type: Grant
    Filed: August 29, 2017
    Date of Patent: August 4, 2020
    Assignee: HeartWare, Inc.
    Inventors: Jeffrey A. LaRose, Charles R. Shambaugh
  • Patent number: 10661009
    Abstract: A fluid control device includes an interface to a remote fluid monitoring sensor that detects fluid flow in a patient. In some embodiments, a processor within the fluid delivery device is programmed to adjust the delivery or withdrawal of fluids based on the fluid flow signals provided by the sensor. In some embodiments, the fluid control device can display and/or record fluid flow signals thereby acting as a hemodynamic monitor.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: May 26, 2020
    Assignee: 1929803 Ontario Corp.
    Inventors: Joseph Eibl, Jon-Emile Kenny
  • Patent number: 10543007
    Abstract: In some examples, a catheter includes an elongated body configured for navigation through vasculature of a patient, the elongated body having an inner wall that defines a lumen extending from a proximal portion to a distal portion. The elongated body is configured to pass a fluid through the lumen and out a distal end of the elongated body. At the distal portion, the inner wall defines a convergent-divergent region such that a diameter of the lumen while moving distally within the elongated body converges from a first lumen diameter to a second lumen diameter and then diverges from the second lumen diameter to a third lumen diameter. The convergent-divergent region is configured to cause a fluid flowing through the lumen to cavitate as the fluid flows through the convergent-divergent region.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: January 28, 2020
    Assignee: Medtronic Vascular, Inc.
    Inventor: Michael Donegan
  • Patent number: 10507277
    Abstract: A blood treatment cassette having a cassette body comprising a hard part and a film that at least partially covers the hard part. The hard part comprises a valve base that cooperates with a section of the film adjacent the valve base to form a valve that is configured to be moved from a first open position in which the valve base and the section of the film do not touch each other to a second position in which the valve base and the section of the film touch each other when a force is applied to the section of the film. The blood treatment cassette comprises a spacer supported by the hard part, and the spacer is configured to apply, in the first position of the valve, force to the section of the film.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: December 17, 2019
    Assignee: Fresenius Medical Care Deutschland GmbH
    Inventor: Martin Lauer
  • Patent number: 10265448
    Abstract: A fluid pump device changeable in diameter is provided. The device has a pump housing which is changeable in diameter and with a rotor which is changeable in diameter. The device has at least one delivery element for fluid, as well as a drive shaft on which the rotor is rotatably mounted. A bearing arrangement is arranged on the drive shaft or its extension, at the distal end of the drive shaft behind the rotor seen from the proximal end of the drive shaft. The bearing arrangement has struts, which elastically brace between a hub of the bearing arrangement and the pump housing.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: April 23, 2019
    Assignee: ECP Entwicklungsgesellschaft MBH
    Inventor: Reiner Liebing
  • Patent number: 10258726
    Abstract: An apparatus for extracorporeal treatment of blood (1) comprising a filtration unit (2), a blood withdrawal line (6), a blood return line (7), an effluent fluid line (13), a pre and/or post-dilution fluid line (15, 25) connected to the blood withdrawal line, and a dialysis fluid line. Pumps (17, 18, 21, 22, 27) act on the fluid lines for regulating the flow of fluid. A control unit (10) is configured to periodically calculate a new value for the patient fluid removal rate to be imposed on an ultrafiltration actuator in order to keep a predefined patient fluid removal rate across a reference time interval irrespective of machine down times.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: April 16, 2019
    Assignee: Gambro Lundia AB
    Inventor: Dominique Pouchoulin
  • Patent number: 10080827
    Abstract: A blood pump comprising a cartridge, the cartridge comprising a first recess therein, said first recess having a surface, and a flexible diaphragm closing said first recess, the first recess and the flexible diaphragm defining a first pump chamber, said first pump chamber having an inlet and an outlet wherein the flexible diaphragm of the first pump chamber is movable between a first position, separated in use from the surface of the first recess, in which said first pump chamber has a maximum volume, and a second position, substantially adjacent to the surface of the first recess, in which said first pump chamber has a minimum volume a pump driver arranged to interface with the cartridge, said pump driver operable to move the flexible diaphragm of the first pump chamber in a first direction into said first recess to, in use, pump blood from the chamber and to move the flexible diaphragm of the first pump chamber in a second direction away from the first recess to, in use, draw blood into said first pump cham
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: September 25, 2018
    Assignee: Quanta Dialysis Technologies Limited
    Inventor: Clive Henry Buckberry
  • Patent number: 10074446
    Abstract: A medical pump for delivering medicament through an IV line to a patient may provide for awareness of the operator and operator authority limiting access by any individual to particular tasks of procedure review, pump programming, pump loading, patient set up, pump operation, and the like associated with the treatment provided by the medical pump. Identifying the operator allows the assignment of particular authority levels to the operators to ensure proper operation of the medical pump, and/or proper operators have made the necessary review to perform the necessary set up of the medical pump facilitating collaborative healthcare delivery. A record of operator intervention and authority levels may be logged to permit an automatic checklist process by the medical pump. Authentication process and pump operation parameters can be communicated through Near Field Communication (NFC).
    Type: Grant
    Filed: February 26, 2015
    Date of Patent: September 11, 2018
    Assignee: Zyno Medical, LLC
    Inventors: Chaoyoung Lee, Todd Sjolander, Mei Zhang
  • Patent number: 9855380
    Abstract: A method for monitoring conveyance of fluid in a device for extracorporeal blood treatment, whereby fluid is conveyed by a peristaltic pump in a fluid system from a low-pressure side to a high-pressure side in that an elastically deformable fluid line positioned between the low-pressure side and the high-pressure side is deformed between a support surface and at least two squeeze elements of a rotor rotating opposite the support surface in such a way that a conveyance volume section is formed between the squeeze elements, whereby a fluid pressure value in the fluid system is detected for the conveyance volume section that is specific to the conveyance volume section, and whereby the detected conveyance-volume-specific fluid pressure value of a conveyance cycle n is compared with the detected conveyance-volume-specific fluid pressure value of a previous conveyance cycle n?x.
    Type: Grant
    Filed: March 30, 2016
    Date of Patent: January 2, 2018
    Assignee: B. BRAUN AVITUM AG
    Inventors: Kai-Uwe Ritter, Christian Schleicher
  • Patent number: 9679111
    Abstract: A method of adjusting a patient's undesired hematocrit and/or hemoglobin concentration to a value within a desired range at a predetermined time with an erythropoiesis stimulating agent (ESA) regimen includes obtaining patient parameters required for input into a model for predicting the patient's hematocrit and/or hemoglobin concentration at a predetermined time with a selected ESA administration regimen, the model including iron homeostasis, and employing the patient parameters and an initially selected ESA administration regimen in the model to predict the patient's hematocrit and/or hemoglobin concentration at the predetermined time with the initially selected ESA administration regimen. The method then includes administering ESA to the patient with an ESA administration regimen predicted to adjust the patient's hematocrit and/or hemoglobin concentration to the desired range at the predetermined time. The method can be implemented in a hemodialysis system.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: June 13, 2017
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Doris Helene Fuertinger, Franz Kappel, Peter Kotanko, Nathan W. Levin, Stephan Thijssen
  • Patent number: 9610420
    Abstract: A CPAP device for delivering pressurized, humidified breathable gas for a patient includes a flow generator configured to pressurize a flow of breathable gas. The flow generator includes an air outlet and a removable water container configured to humidify the pressurized breathable gas received from the flow generator. The water container includes an air inlet and an air outlet. The CPAP device further includes a first elastomeric face seal configured to sealingly abut against a substantially flat portion of the water container surrounding the water container air inlet, the first elastomeric face seal being located at an intermediate position between the flow generator air outlet and the water container air inlet when the water container is placed into position to pneumatically communicate with the flow generator.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: April 4, 2017
    Assignee: ResMed Limited
    Inventors: Perry David Lithgow, Alexander Virr, Duncan Lovel Trevor-Wilson, Andrew Roderick Bath, Michael Thomas Janiak, Dan Kao, Jim Saada
  • Patent number: 9555177
    Abstract: A needle guard is used when suturing the cuff of an attachment ring to the heart. The needle guard is disposed in the attachment ring to prevent other parts of the attachment ring from being punctured by a suturing needle. The needle guard can include one or more grooves to inhibit relative movement between the needle guard and the attachment ring during suturing. The needle guard is removed upon completion of suturing and to allow insertion into attachment ring of an inflow conduit of a heart assist device. An articulated clamp is used to compress the attachment ring into engagement with the inflow conduit. The attachment include an annular rib that grabs the inflow conduit.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: January 31, 2017
    Assignee: THORATEC CORPORATION
    Inventors: Donald Curtis, Alicia Baumberger, John Mark Di Paola, Carine Hoarau, Nathan Harold, Fabian Franco
  • Patent number: 9539389
    Abstract: A flow rate sensor is provided in a wireless, leadless package. The flow rate sensor includes a MEMs sensor coupled to an ASIC and an antenna. The flow rate sensor is powered by radiation received from a control module adjacent the flow rate sensor. The flow rate sensor is placed within a fluid and monitors the flow rate of the fluid. The control module is not in the fluid and receives flow rate data from the flow rate sensor.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: January 10, 2017
    Assignee: STMicroelectronics, Inc.
    Inventors: Nicholas Trombly, Patrick Furlan
  • Patent number: 9494150
    Abstract: The present invention involves, in some embodiments, medical systems for pumping fluid using a medical-grade cartridge configured for use in a reusable fluid medical apparatus to move liquids through the cartridge. The cartridge includes a membrane defining a chamber. The system includes a pressure source able to be placed in pneumatic communication with the chamber to adjust gas pressure therein. The system further includes a processor configured to perform a dry integrity test based on adjustment and measurement of fluid pressures in the chamber in which neither side of the member is exposed to liquid during test to determine whether a fluid leak exists through the membrane.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 15, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr., Geoffrey P. Spencer
  • Patent number: 9488167
    Abstract: The present invention involves, in some embodiments, systems and methods for performing an integrity test on a medical grade cassette that is configured to be used on a medical fluid handling system, wherein the cassette may be disposable and may comprise a membrane therein. The test may be configured to determine an error condition, such as detection of membrane leakage above a threshold value, and may in certain cases be implemented by a medical computer system. In certain cases the integrity test is a dry integrity test and in certain cases, the test is configured to determine a leakage rate of fluid through the membrane.
    Type: Grant
    Filed: May 29, 2014
    Date of Patent: November 8, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Larry B. Gray, Robert J. Bryant, Jr., Geoffrey P. Spencer
  • Patent number: 9482216
    Abstract: In various embodiments, a surgical cassette, configured to engage peristaltic pump rollers, may include two or more pump segments between a sheet and a substrate coupled to the sheet. The two or more pump segments on the cassette may produce additional flow (e.g., approximately twice the flow for two segments as opposed to one) than if the cassette had only one pump segment engaging the roller. Further, in some embodiments, the two or more pump segments and rollers on the roller head may be configured to provide a flow profile in which a peak of a pulse from a first pump segment is at least partially out of phase with a peak of a pulse from the second pump segment. The combined resultant flow may then have a flow profile with pulsation amplitudes that are smaller than the individual pump segment pulsation amplitudes.
    Type: Grant
    Filed: June 12, 2014
    Date of Patent: November 1, 2016
    Assignee: Alcon Research, Ltd.
    Inventor: Gary P. Sorensen
  • Patent number: 9452285
    Abstract: Aspects of the present invention relate to electroporation devices and methods of using same to effectively facilitate the introduction of a biomolecule into cells of a selected tissue in a body, in particular skin such as intradermic or subcutaneous tissue. In some aspects, the present invention is a skin EP device, which produces a pulse of energy and delivers same to the skin tissue using a skin electrode array and maintains a constant current in the same skin tissue based on user input, including a preset current, and allows the storage and acquisition of current waveform data.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: September 27, 2016
    Assignee: VGX Pharmaceuticals, Inc.
    Inventors: Ruxandra Draghia-Akli, Amir S. Khan
  • Patent number: 9412699
    Abstract: The semiconductor device has insulating films 40, 42 formed over a substrate 10; an interconnection 58 buried in at least a surface side of the insulating films 40, 42; insulating films 60, 62 formed on the insulating film 42 and including a hole-shaped via-hole 60 and a groove-shaped via-hole 66a having a pattern bent at a right angle; and buried conductors 70, 72a buried in the hole-shaped via-hole 60 and the groove-shaped via-hole 66a. A groove-shaped via-hole 66a is formed to have a width which is smaller than a width of the hole-shaped via-hole 66. Defective filling of the buried conductor and the cracking of the inter-layer insulating film can be prevented. Steps on the conductor plug can be reduced. Accordingly, defective contact with the upper interconnection layer and the problems taking place in forming films can be prevented.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: August 9, 2016
    Assignee: SOCIONEXT INC.
    Inventor: Kenichi Watanabe
  • Patent number: 9383288
    Abstract: A monitoring device is arranged to receive a time-dependent measurement signal from a pressure sensor in a fluid containing system, which is associated with a first pulse generator and a second pulse generator. The pressure sensor is arranged in the fluid containing system to detect a first pulse originating from the first pulse generator and a second pulse originating from the second pulse generator. The monitoring device is configured to process the measurement signal to remove the first pulse. In this process, the monitoring device receives the measurement signal, obtains a first pulse profile which is a predicted temporal signal profile of the first pulse, and filters the measurement signal in the time-domain, using the first pulse profile, to essentially eliminate the first pulse while retaining the second pulse. The fluid containing system may include an extracorporeal blood flow circuit and a blood circuit of a human patient.
    Type: Grant
    Filed: May 5, 2014
    Date of Patent: July 5, 2016
    Assignee: Gambro Lundia AB
    Inventors: Kristian Solem, Bo Olde
  • Patent number: 9375526
    Abstract: This disclosure relates to vial spiking assemblies and related methods. In certain aspects, the vial spiking assemblies include a vial adapter having a base, a spike extending from a central region of the base, and a sidewall extending from the base and surrounding the spike. The base and the sidewalls partially, define a cavity that is configured to receive at least a portion of the vial. The assemblies also include a spike cover that is removably attached to the spike and that includes a material configured to indicate when the material is contacted with liquid.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: June 28, 2016
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Nigel Wright, Michael John Zang, Tom Monahan, John A. Barron, Douglas Mark Zatezalo
  • Patent number: 9295769
    Abstract: According to one embodiment, a dialysis device is made available that can be implanted at least partially into the body of a patient and comprises a blood chamber, through which the patient's blood can flow, a dialysis chamber for receiving a dialysate, and a hydraulic pump device for compressing the two chambers alternately by means of a hydraulic fluid, wherein both chambers are each equipped with two valves for controlling the inflow and outflow of blood and dialysate, respectively, and wherein both chambers are connected to each other in an area designed as a membrane.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: March 29, 2016
    Assignee: DUALIS MEDTECH GMBH
    Inventors: Wolfgang Schiller, Thomas Schmid, Hiep T Nguyen
  • Patent number: 9272082
    Abstract: A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: March 1, 2016
    Assignee: DEKA Products Limited Partnership
    Inventors: Jason A. Demers, Michael J. Wilt, Kevin L. Grant, James D. Dale, Brian D. Tracey