Abstract: An injection shut-off valve for insertion into an infusion line comprises a housing with connections for inlet and outlet lines. The housing includes an orifice for introducing an injection syringe. A valve is installed in the housing and includes a deformable diaphragm. In a non-injection state, the valve device seals off fluid flow between the inlet and outlet lines on the one hand and the orifice on the other. During injection, the diaphragm is deformed to create an opening such that fluid flow from the inlet to the housing is shut off. During deformation of the diaphragm the orifice is brought into fluid carrying communication with the outlet line from the housing, thus making it possible for the injection fluid to pass through the housing into the outlet line, and to a patient.

Abstract: The invention provides a tamper evident package for a solid oral drug dose that, after being opened, may be used for administering the dose to a patient without removing the dose from the package. The invention also provides a method for using a package for a solid oral drug dose as an aid in administering the dose contained within the package to a patient. The method of administering the packaged drug takes advantage of the normal swallowing reflex, thus facilitating oral ingestion of the dose, and positively identifies the drug up to an including the act of drug ingestion by the patient.

Abstract: Disclosed is a system for administering medication through the nasal passage of a patient into the patient's stomach. The system includes a connector having a body member with the passageway therein and extending between open ends in the body member. At each of these ends is a series of flanges with tapered edges. One of these ends is inserted into a tube extending through a patient's nose and into the patient's stomach. The other end is connected to either a suction or feeding pump at the appropriate time by a nurse. Within the body member is a port through which medication is introduced. A valve at the port either opens or closes the passageway as required.

Abstract: An elastomeric member having one or more preformed, self-sealing slits and which and dilate at predetermined pressures to form a fluid flow path. In an undilated condition, reverse flow is prevented.In various embodiments, an elastomeric infusion manifold is disclosed having a plurality of self-sealing slits formed therein relative to either a center lumen, a center slit or in independent relation to one another. Individual, hole mounting, fingered compression-type clamps permit a one-handed connection to the manifold.In other embodiments, catheters are disclosed having lengthwise co-extensive self-sealing, flow channels, comprising slit containing core members, integral slit containing solid portions or solid core members mounted within the catheter lumen such that flow occurs in the space between the core and the catheter walls. Conventional leur lock connectors or compression-type clamp connectors are useable therewith.

Abstract: A formulation chamber is disclosed comprising a wall surrounding a lumen containing a device for delivering a beneficial agent. The chamber has an inlet for admitting a fluid into the chamber and an outlet for letting an agent formulation leave the chamber. The chamber is adapted for use in an intravenous delivery system for delivering an agent formulation to a patient.

Abstract: A catheter manifold for an angioplasty balloon catheter assembly houses a plurality of serially arranged luers. Longitudinal sections of the luers are joined by tubular connectors, and with the connectors form a central passage through the manifold. At the most distal tubular connector is a reduction in passage diameter. A plurality of elongate, longitudinally directed flutes are formed in that connector just proximal of the diameter reduction. The flutes are engaged by a guide wire insertion tube or fiber insertion tube as it is loaded into the manifold, and tend to center the tube in the passageway. The flutes tend to maintain it in coaxial relation to the passageway, while permitting fluids from the proximal luers to flow in the passageway exteriorly of the tube.

Abstract: A novel acute care cerebral support system and method for treating severly ischemic brains is disclosed wherein an oxygenated nutrient emulsion is circulated through at least a portion of the ventriculo-subarachnoid spaces. The nutrient emulsion contains an oxygenatable non-aqueous component, an aqueous nutrient component, an emulsification component, and other components which render physiologic acceptability to the nutrient emulsion. The disclosed system and method have been shown to effectively exchange oxygen, carbon dioxide, glucose, and other metabolites in severely stroked brains. Significant restoration of oxidative metabolism and electrographic activity result from the disclosed treatment. Methods for producing the nutrient emulsion and a system for delivering that emulsion to the cerebrospinal pathway are also disclosed. Additionally, novel diagnostic methods for diagnosing the physiologic state of hypoxic-ischemic and other diseased neurologic tissue during treatment are provided.

Abstract: A self contained portable apparatus for the rapid warming and infusion of massive amounts of a parenteral fluid into a patient under conditions where time is of the essence. The apparatus comprises a portable cabinet, a parenteral fluid supply system, a fluid warming system, and apparatus monitoring and failure warning systems. The portable cabinet has a rectangular shaped enclosure which houses portions of the fluid supply and warming systems and the monitoring and failure warning systems. Extending upwardly from the top of the rectangular enclosure is a vertical support member which carries upper and lower horizontal crossmembers. The upper crossmember carries a plurality of disposable parenteral fluid bags and their respective pressure cuffs which surround the bags.

Abstract: An infusion device is disclosed having an improved valving apparatus with the valving apparatus being configured to substantially preclude formation of volumetric dead spaces. The valving apparatus is typically utilized to allow introduction of one or more secondary fluids, such as drugs, into a patient during normal infusion of the primary fluid into the patient, with such insertion being effected through a secondary conduit connected to the primary infusion conduit through the valving apparatus. The valving apparatus includes a movable element that is positioned adjacent to the inner wall of the primary conduit so that the movable element forms a one-way valve thereat.

Abstract: A colonic lavaging machine has a pressure switch operable by pressure in a water supply line to a speculum. The pressure switch is coupled with a valve that cyclically controls the flow of waste water from the speculum.

Abstract: The catheter includes multiple lumens which connect to a single mixing chamber at the catheter hub. Each of the multiple lumens is connected both to the mixing chamber and to a port connected to a catheter connector. By selecting a plug of suitable length, one or more of the side ports connected to the central mixing chamber can be plugged whereby the connection from that particular side port will be prevented from going into the mixing chamber. Accordingly, it is possible to have a single catheter connection into the mixing chamber which connects to multiple lumens of the catheter without any additional plumbing requirements.

Abstract: Automated peritoneal dialysis apparatus for providing dialysis solution to a patient and including bracket means for receiving and holding a multiple junction connector of a flexible conduit set member carried by the apparatus. The bracket means is adapted to hold the multiple junction connector in only a single position of orientation whereby flexible conduits of the set member extending from the connector are naturally directed toward their intended destination stations.

Abstract: A pump-actuated sequencing valve for sequentially administering, to a patient, two fluids contained in separate respective reservoirs, wherein the fluid is pumped from a first one of the two reservoirs by means of a pump associated therewith. The valve comprises a first portion connected to the first reservoir, a second portion connected to the second reservoir, and a third portion connected between the first and second portions, on the one hand, and the patient, on the other hand. The second portion includes a ball valve which is pressure-responsive to operation of the pump for blocking flow of fluid to and from the second reservoir, thus blocking both forward flow from the second reservoir and backflow from the sequencing valve toward the second reservoir.

Abstract: A medical device is disclosed herein for patient care in connection with syringe and catheter drainage and feeding procedures which includes an elongated, flexible extension tube having an adapted plug or fitting at each end and a control clamp operably carried along the length of tube. Each plug or fitting is provided with a pair of dissimilar sized connections adapted to insertably receive a plurality of sized syringe or catheter dispensing nozzles or tips. Caps are provided for covering the connections and a flexible clip is employed for releasably attaching the device to a support or to the clothing of an attending nurse or the patient himself.

Abstract: A manifold for sequentially dispensing a plurality of solutions through an intravenous supply catheter. The manifold includes a disposable tubing manifold that is connected to each of the solutions to be administered. Flow of solution through the branches of the tubing manifold can be stopped by valves which engage each branch. The quantity of solution dispensed is metered by a volumetric infusion pump and controlled by sequentially opening and closing the valves individually.

Abstract: A system for achieving cardioplegia, a protective cessation of the heart muscle activity during open heart surgery which includes providing a circulation system in parallel with the main life support system and deriving a blood source from the arterial reservoir of the main life support system, moving blood from said source through a cooling heat exchanger for selective discharge to the aorta of the heart patient or to a cardiotomy reservoir in the main life support system. The system includes a means for titration of medication to the blood and temperature control and monitoring equipment.

Abstract: A feminine hygienic device for use with a pressurized water supply, the feminine hygienic device comprising a housing configured to be coupled to the pressurized water supply wherein the housing includes a mixing chamber having a fluid reservoir formed therein, an inlet port having a one-way control valve disposed therein to contain fluid medication in the mixing chamber and to selectively control the flow of water from the pressurized water supply to the mixing chamber, a first outlet port having a quick disconnect coupling device disposed adjacent thereto and a second outlet port having a diverter control valve having at least two positions disposed in operative communication therewith to selectively control the flow of liquid from the mixing chamber through the first and second outlet ports in combination with a dispensing nozzle including a flow control and metering control coupled to the first outlet port to selectively control the flow of liquid from the mixing chamber through the dispensing nozzle for