Having Means Inflated In Body (e.g., Inflatable Nozzle, Dilator, Balloon Catheter, Occluder, Etc.) Patents (Class 604/96.01)
  • Patent number: 11311369
    Abstract: An implant-delivery sleeve may comprise an enclosure having at least one opening and at least one vent conduit. The vent conduit may extend along a surface of the enclosure to assist in removing fluids (e.g., blood and air) from the tissue pocket to facilitate implantation of the implant.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: April 26, 2022
    Assignee: MENTOR WORLDWIDE LLC
    Inventors: Krasimira Hristov, Clifford Dwyer, James Fleming, Robert Tannhauser, Leo Kriksunov
  • Patent number: 11305098
    Abstract: Inflatable devices are disclosed including a surface which has a network of polymer chains and is configured to be inflatable into a therapeutically or diagnostically useful shape, and at least one ultrashort laser pulse-formed modification in the surface. The network can, for example, include a network morphology that is substantially unchanged by modification with the ultrashort pulse laser. Ultrashort laser pulses can be laser pulses equal to or less than 1000 picoseconds in duration. Advantageously, the etching process uses a relatively low-heat laser to avoid significant heating of surrounding polymers while modifying the surface (and other structures) of the device. The process is configured so that the polymer chain morphology adjacent the modification is substantially unaffected by the low-heat laser. The resulting inflatable device has customized surface features while still retaining substantially homogenous polymer network morphology.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: April 19, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Pu Zhou, Bin Tian, Yidong M. Zhu
  • Patent number: 11266820
    Abstract: A system includes a platform configured for insertion into a user's nostril and a catheter. The platform includes a board having first and second major surfaces and a support extending from the board. The support includes an aperture therethrough. The catheter includes an inflatable tube and a lumen having first and second ends, the first end connected to the tube and the second end connected to a pressurized fluid source for inflating the tube. The tube is configured for insertion through the aperture. A method includes inserting a platform into a user's nostril, inserting a catheter through an aperture of the platform, and inflating a tube of the catheter. Inflating the tube is accomplished by introducing a pressurized fluid through a lumen of the catheter, to thereby cause the tube to conform to a passage of the user's nasal or pharyngeal region.
    Type: Grant
    Filed: January 16, 2018
    Date of Patent: March 8, 2022
    Inventor: Robert S. Bridge
  • Patent number: 11246653
    Abstract: A plurality of catheter-based ablation apparatus embodiments are provided that address several areas of atrial target tissue and which feature firm and consistent ablation element to tissue contact enabling the creation of effective continuous lesions.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: February 15, 2022
    Inventor: Boaz Avitall
  • Patent number: 11207510
    Abstract: An applicator is disclosed for applying a treatment solution to a treatment site of a patient. The applicator can include an applicator housing comprising a treatment solution reservoir. A cartridge can be removably disposed in the housing. The cartridge when arranged in the housing can be in fluid communication with the treatment solution reservoir. The cartridge can include an electrostatic module for electrostatically charging the treatment solution in the treatment solution reservoir; and a nozzle for applying the treatment solution.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: December 28, 2021
    Assignee: Octet Medical, Inc.
    Inventor: Clifford A. Wright
  • Patent number: 11202891
    Abstract: A balloon catheter is described, having a reinforced, co-axial, duel lumen design. At least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: December 21, 2021
    Assignee: MicroVention, Inc.
    Inventors: Joseph A. Gulachenski, Roland Guyon, Cathy Lei, Nelson Peralta, Tadele Haile Wolde-Meskel, Russell Corvese
  • Patent number: 11179552
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: November 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11179551
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: November 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 11147952
    Abstract: A medical device includes an inflatable balloon defining an interior surface and an exterior surface, and a coating including a therapeutic agent disposed on the exterior surface of the inflatable balloon. The coating has a release transition temperature within a range from about 25° C. to about 50° C. When the temperature of the coating is below the release transition temperature, the coating retains at least a portion of the therapeutic agent on the exterior of the inflatable balloon. When the temperature of the coating is above the release transition temperature, the coating releases at least a portion of the therapeutic agent from the exterior of the inflatable balloon.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 19, 2021
    Assignee: Medtronic Vascular, Inc.
    Inventors: Adam Shipley, Tony Le, Rajesh Radhakrishnan, Terry Morgan
  • Patent number: 11129737
    Abstract: A locking assembly for releasably coupling a first elongate member to a second elongate member is provided. The locking assembly can include a first lumen for anchoring the locking assembly to a catheter and a second lumen for releasably retaining a guidewire to the locking assembly. A release member can interface with the locking assembly and apply a force that decouples the guidewire from the locking assembly.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: September 28, 2021
    Assignee: Endologix LLC
    Inventors: Kevin Chu, Rolando Lee, Craig Welk, Bryant Tran
  • Patent number: 11065141
    Abstract: The reconstrainment band includes a hollow generally tubular shaped band having proximal and distal ends and having an exterior surface for engaging a stent and an interior surface for engaging a delivery tube. The exterior surface has at least one fin projecting therefrom along the longitudinal axis of the band. The fin has at least one obtusely shaped surface relative to the longitudinal axis and facing one of the ends. The reconstrainment band is included in a delivery device for intraluminally positioning and deploying a radially distensible stent. Reconstrainment of a partially deployed stent is provided by the delivery device.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: July 20, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Mark D. Wood, John J. Damarati, John O. McWeeney
  • Patent number: 11033326
    Abstract: Technologies are described for an endoscopic duct clearing system. A cannula can be shaped to pass through an endoscope within an esophagus, into a duodenum, and through an incision in a duodenal papilla. A capture basket may be deployed from a distal end of the cannula. A hand control at the proximate end of the cannula may be operable to position the distal end of the cannula from outside the endoscope into proximity of blockage material. A suction line may be coupled from a suction source to the proximate end of the cannula. A suction control may be coupled to the suction source. The suction control may be operable to adjust a level of suction drawn by the suction source through the distal end of the cannula. The suction control may be adjusted to draw the blockage material against or into the cannula for removal from the patient.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: June 15, 2021
    Inventor: Anthony DiTomaso
  • Patent number: 11033318
    Abstract: Methods and devices for treating nasal airways are provided. Such devices and methods may improve airflow through an internal and/or external nasal valve, and comprise the use of mechanical re-shaping, energy application and other treatments to modify the shape, structure, and/or air flow characteristics of an internal nasal valve, an external nasal valve or other nasal airways.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: June 15, 2021
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 11013896
    Abstract: A device and method for dilating a Eustachian tube of a patient is disclosed. The device includes a guide catheter and a balloon dilation catheter. The balloon dilation catheter has an actuator that prevents injury to the middle ear. The balloon dilation catheter is slidably coupled with the guide catheter through the guide catheter lumen and is fully inserted into the guide catheter lumen when the distal side of the actuator is adjacent to the proximal end of the guide catheter. The method involves advancing the guide catheter and balloon dilation catheter through a nasal passage of the patient to dilate a portion of the Eustachian tube.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 25, 2021
    Assignee: Acclarent, Inc.
    Inventors: Randy S. Chan, Hung V. Ha, Andy Nguyen, Ketan P. Muni
  • Patent number: 11000670
    Abstract: A flexible kink-resistant introducer sheath (10). The introducer sheath includes an inner liner (31), a coil (33) and an outer tube (33). The inner liner includes a passageway (30) extending longitudinally therethrough, where a catheter (50) can be advanced through the passageway. The coil (33) has a plurality of turns positioned longitudinally and compression fitted around the inner liner (31), where the turns have a predetermined spacing therebetween. The outer tube (20) is positioned longitudinally around the coil (33) and the inner liner (31), and is connected to the inner liner through the spaces between the turns. A diameter difference between the inner liner and the catheter is in a range of about 0.0005 to about 0.004 inch (0.013 to about 0.10 mm).
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: May 11, 2021
    Assignee: Cook Medical Technologies LLC
    Inventors: John J. Connors, III, Christopher G. Dixon, Ray Leonard, II
  • Patent number: 10994109
    Abstract: There are provided a connectable catheter system, device and methods of use thereof. The connectable catheter system, comprising: an intermediary catheter comprising an external section and a tip section, the tip section is configured to be inserted into a body of a subject; and a reconnectable indwelling stent comprising a connecting section and a target section, the target section being configured to be located within a body of the subject, wherein the connecting section of the reconnectable indwelling stent is configured to reversibly connect, within the subject body, to the tip section of the intermediary catheter to form a continuous conduit between the intermediary catheter and the reconnectable indwelling stent.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: May 4, 2021
    Assignee: Urogen Pharma Ltd.
    Inventors: Gil Hakim, Yosh Dollberg, Nadav Malchi
  • Patent number: 10993755
    Abstract: An inflatable bone tamp is provided that includes a shaft with proximal and distal portions and a central longitudinal axis. A balloon is attached to the shaft such that a material can flow through the shaft and into the balloon to inflate the balloon. A flow controller controls the flow of the material through the shaft and into the balloon. Kits, systems and methods are disclosed.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: May 4, 2021
    Assignee: MEDTRONIC HOLDING COMPANY SÀRL
    Inventors: Calin Druma, Shankar Kar
  • Patent number: 10980986
    Abstract: A balloon catheter includes a shaft extending in one direction; a balloon disposed on the shaft; a first lubrication region; and a second lubrication region. The balloon in an expanded state includes a straight pipe portion; a first tapered portion disposed at a first end of the straight pipe portion in a long axis direction of the shaft; and a second tapered portion disposed at a second end of the straight pipe portion positioned opposite to the first end of the straight pipe portion in the long axis direction. Each of the first tapered portion and the second tapered portion tapers away from the straight pipe portion, and the first lubrication region extends over the straight pipe portion and the first tapered portion.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: April 20, 2021
    Assignee: KANEKA CORPORATION
    Inventor: Toshiya Kisa
  • Patent number: 10973566
    Abstract: Instrument and systems for applying ablative energy to epicardial tissue via a subxiphoid access surgical approach. The instrument has a head assembly sized and shaped for a subxiphoid surgical approach to a patient's heart and defines a contact face. The head assembly includes a paddle body, a first ablation electrode, and a second ablation electrode. The ablation electrodes are coupled to the paddle body in a spaced apart, spatially-fixed fashion. The ablation electrodes are exteriorly exposed at the contact face. A tubular member extends from the head assembly and maintains wiring connected to the ablation electrodes. The instrument is manipulable to locate the contact face on epicardial tissue of a patient's heart via a subxiphoid surgical approach, such as between the left and right pulmonary vein junctions of the posterior left atrium.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: April 13, 2021
    Assignee: Medtronic, Inc.
    Inventors: James Skarda, Steven Bolling, Daniel Cheek, Brian Ross, Mitchell Strain, Steve Ramberg, Thomas J Conway, Randy Thill
  • Patent number: 10974031
    Abstract: A catheter adapted to slidably receive a hollow shaft through its lumen. An expandable balloon is attached to the distal portion of the hollow shaft. A nose piece disposed at the front face of the balloon forms a connection between the balloon and the distal portion of the hollow shaft. When the balloon is expanded the nose piece does not protrude beyond the front face of the balloon.
    Type: Grant
    Filed: December 28, 2017
    Date of Patent: April 13, 2021
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Assaf Govari, Christopher Thomas Beeckler, Joseph Thomas Keyes
  • Patent number: 10926069
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: May 5, 2020
    Date of Patent: February 23, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10912873
    Abstract: Various systems and methods are provided for reducing pressure at an outflow of a duct such as the thoracic duct or the lymphatic duct. A catheter system can include a catheter shaft configured to be at least partially implantable within a patient's vein, a flexible membrane attached to the catheter shaft, the flexible membrane being a collapsible, tube-like member having a lumen extending therethrough, and a single selectively deployable restriction member formed over a portion of the flexible membrane at substantially a midpoint between a proximal end of the flexible membrane and a distal end of the flexible membrane, the restriction member being configured to control a size of the lumen so as to direct a controlled volume of fluid from an upstream side of the restriction member to a downstream side the restriction member.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: February 9, 2021
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Sagi Raz, Shani Chen, Or Inbar
  • Patent number: 10905852
    Abstract: A urinary catheter is disclosed, comprising a tubular shaft extending between an insertable end and a discharge end, and a tip fixedly connected to said insertable end of the tubular shaft. The tip has an outer diameter which at all places is equal to or lower than the outer diameter of the tubular shaft, and is very soft, so that the hardness of the tip is equal to or lower than 60 micro Shore A. It has been found that such a soft tip provides a catheter which is easier to insert into the urethra, in particular in urethras providing various types of obstacles. A corresponding method of manufacturing is also disclosed.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: February 2, 2021
    Assignee: DENTSPLY IH AB
    Inventors: Martin Nyman, Niklas Dahlberg
  • Patent number: 10898384
    Abstract: A dilation catheter includes a shaft and an expandable element. The shaft includes a proximal portion and a distal portion. The distal portion includes a tip and a bend. The tip is sized and configured to pass through an isthmus of a Eustachian tube (ET). The bend is proximal to the tip. The bend is formed at an angle configured to provide insertion of the tip into the isthmus of the ET via an ear canal associated with the ET. The expandable element is disposed at the distal portion of the shaft. The expandable element is configured to transition between a non-expanded state and an expanded state. The expandable element in the non-expanded state is configured for insertion into the ET via the isthmus. The expandable element in the expanded state is configured to dilate the ET.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: January 26, 2021
    Assignee: Acclarent, Inc.
    Inventors: Randy S. Chan, Ketan P. Muni, Hung V. Ha, Andy Nguyen, Holger Sudhoff, Sivette Lam, Marc Dean, Dennis S. Poe
  • Patent number: 10881840
    Abstract: The present invention provides a stretchable material suitable for use in an inflatable medical device. The stretchable material has at least one reinforcing polymer layer with a top and bottom side forming a porous matrix which is imbibed with a sealing material to infiltrate and substantially seal spaces of the porous matrix and extend beyond the reinforcing polymer layer to form a surface coating.
    Type: Grant
    Filed: January 29, 2018
    Date of Patent: January 5, 2021
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Alex R. Hobson, Michael Houghton, David R. King, Joseph E. Korleski, Jr., Brian C. Lentz, Kenneth Newcomb, Peter J. Roeber, John Streeter
  • Patent number: 10881460
    Abstract: A medical device to be inserted in a defect blood vessel, body cavity, or body duct for treatment thereof is disclosed, wherein it comprises an essentially cylindrically formed elongated resilient sheath device (2) wherein it has a distal end (3) and a proximal end (4), wherein said sheath device (2) along its circumferential surface in the axial direction is provided with a slotted opening (5) having connection with a first bore (6) arranged in the axial direction of said sheath device (2), said first bore (6) having the ability to house an elongated fiber body (7), wherein said sheath device (2) has the ability to be clamped around a major part of the perimeter of said fiber body (7), and wherein said sheath device (2) in its axial direction also is provided with a second bore (8) having the ability to house an injection means (9), as well as a kit containing said medical device, and a method for treatment of defective blood vessels, body cavities, and body ducts by use of said medical device.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: January 5, 2021
    Assignee: MedV ASC AB
    Inventor: Michael Åkesson
  • Patent number: 10849879
    Abstract: Pharmaceutical preparations, compositions, systems, and devices including medical devices and diagnostic or therapeutic agents, and methods to treat disease by modification of local tissue environment to modulate the therapeutic index of locally or systemically delivered therapeutic or diagnostic agents. Improved ability to reduce sympathetic nerve activity in the adventitia and perivascular tissues around arteries and veins in the body. Modulation of the local tissue environment around an artery to enable more effective denervation with or without a therapeutic agent. Modulation may include adjustment of the pH of the tissue.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: December 1, 2020
    Assignee: MERCATOR MEDSYSTEMS, INC.
    Inventor: Kirk P. Seward
  • Patent number: 10821272
    Abstract: An apparatus, including a flexible insertion tube having a distal end for insertion into a body cavity, and first and second conduits configured to deliver first and second fluids, respectively, to the distal end. The distal end includes a first balloon coupled to the first conduit so that the first fluid inflates the first balloon and is delivered, via one or more spray ports in the first balloon, to tissue in the body cavity, a second balloon contained within the first balloon and coupled to the second conduit so that the second fluid inflates the second balloon, and multiple splines including a flexible, resilient material and extending along a longitudinal axis of the distal end, and configured to constrain the second balloon so that inflation of the second balloon creates lobes that form, along the longitudinal axis between the lobes, channels that direct the first fluid to the spray ports.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: November 3, 2020
    Assignee: BIOSENSE WEBSTER (ISRAEL) LTD.
    Inventors: Kevin Justin Herrera, Assaf Govari, Andres Claudio Altmann
  • Patent number: 10813739
    Abstract: An apparatus includes a delivery catheter having a deployable dynamic valve that dynamically opens and closes in response to relative fluid pressure thereabout, particularly while in an anatomical lumen. The valve is maintained in a collapsed configuration during introduction to a treatment site. The valve is adapted to automatically move from the collapsed configuration to a deployed configuration at the treatment site.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: October 27, 2020
    Assignee: Surefire Medical, Inc.
    Inventors: James E. Chomas, Leonard Pinchuk, John Martin, Aravind Arepally, Brett E. Naglreiter, Bryan M. Pinchuk
  • Patent number: 10813680
    Abstract: Devices, systems, and methods for assessing contact between a treatment element and an area of target tissue using resistive-type and/or capacitive-type contact sensing elements. In one embodiment, a medical system for determining tissue contact includes an elongate body including a distal portion and a proximal portion and a treatment element coupled to the elongate body distal portion. The treatment element may have a first expandable element, a second expandable element, the first expandable element being within the second expandable element, and at least one contact sensing element between the first and second expandable elements. In one example, the device may include a plurality of contact sensing elements arranged in a matrix or in a plurality of linear configurations. In another example, the device may include a layer of conductive microparticles or a contact-sensing film.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: October 27, 2020
    Assignee: Medtronic CryoCath LP
    Inventor: Nicolas Coulombe
  • Patent number: 10779873
    Abstract: A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: September 22, 2020
    Assignee: AERIN MEDICAL, INC.
    Inventors: Scott J. Wolf, Andrew Frazier
  • Patent number: 10772664
    Abstract: Systems and methods for treating conditions and diseases of the spine are disclosed herein. A device includes a balloon catheter comprising at least one inner lumen incorporated within an elongated shaft; a distal end having an inner balloon positioned inside and completely surrounded by an outer balloon; and a proximal end having an adapter for passage of at least one of an inflation fluid or a medical instrument; and an optical fiber comprising an outer diameter sized to pass through the inner lumen of the elongated shaft; a nonlinear light-emitting portion of a given length, wherein a portion of a cladding material from the nonlinear light-emitting portion has been removed so that light energy may be emitted along the length of the nonlinear light-emitting portion; and a linear elongated portion for guiding light towards the nonlinear light-emitting portion.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: September 15, 2020
    Assignee: IlluminOss Medical, Inc.
    Inventors: Robert A Rabiner, Gene P. DiPoto
  • Patent number: 10729455
    Abstract: An obstruction removal device is described, having one or more engaging members which can engage portions of the clot. The one or more engaging members have a collapsed, delivery state, and an expanded, deployed state which in some embodiments can be locked to maintain its fixed configuration.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: August 4, 2020
    Assignee: MicroVention, Inc.
    Inventors: Mayank Goyal, Jared Shimizu, Heath Bowman, Kiet Lam
  • Patent number: 10722683
    Abstract: There is provided a microcatheter having a proximal solution lumen and a distal tip portion with a guidewire lumen. The microcatheter and methods of use thereof allows for introduction of solution into a vessel while manipulating the guidewire and/or the microcatheter itself. The solution may be a contrast solution, for viewing of the vessel, a therapeutic or diagnostic solution, or any other type of solution.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: July 28, 2020
    Assignee: THERMOPEUTIX, INC.
    Inventors: Ronald Jay Solar, Yoav Shaked, Glen Lieber
  • Patent number: 10716669
    Abstract: A delivery system for delivery of a radially expandable device to an implantation site in a patient, the delivery system including an elongated tubular member comprising a distal tip and an outer surface, first and second balloon portions spaced proximally from each other and the distal tip along a length of the tubular member, an annular space between the first and second balloon portions, a plurality of clip deployment tubes extendably moveable relative to the outer surface of the tubular member, and a plurality of clips, wherein each clip is moveable within a length of one of the clip deployment tubes between a retracted position and a deployed position.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: July 21, 2020
    Assignee: Medtronic, Inc.
    Inventors: Damian Jelich, Ana Menk, Jason Quill, Gilbert Tang
  • Patent number: 10709878
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: July 14, 2020
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10639460
    Abstract: Systems, methods, and devices are provided for the treatment of edema. In one aspect a method for implanting an indwelling catheter within a vein of a patient is provided. The catheter can extend from a position upstream of at least one outflow port of a duct of the lymph system to a terminal position downstream of the at least one outflow port. In use, a first restriction can be created within the vein proximal to a distal region of the catheter. The first restriction can define a localized low pressure zone distal of the restriction and within a portion of the vein housing the catheter. The low pressure zone can be adjacent to the at least one outflow port to enable fluid to pass from the at least one lymph duct outflow port into the vein.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: May 5, 2020
    Assignee: White Swell Medical Ltd
    Inventors: Yaacov Nitzan, Menashe Yacoby, Tanhum Feld
  • Patent number: 10639245
    Abstract: The group of inventions relates to the field of aesthetic, plastic and reconstructive cosmetology/medicine, and more particularly to meso threads used for remedying aesthetic and age-related changes to the skin, and to methods for producing such threads. Proposed is a multicomponent meso thread consisting of a core and a shell. The core is realized in the form of a fibroin thread, and the shell contains hyaluronic acid or a salt thereof or a polyelectrolyte complex of hyaluronic acid or a salt thereof and chitosan or a salt thereof. Also proposed are a variant of the thread having a plastifying agent in the shell, and methods for producing the proposed meso threads.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: May 5, 2020
    Assignee: MARTIN'EX International Research and Development Centre
    Inventors: Natal'ya Pavlovna Mihajlova, Mihail Anatol'evich Selyanin, Sergej Alekseevich Uspenskij
  • Patent number: 10625073
    Abstract: Devices, systems, and methods for specializing, monitoring, and/or evaluating therapeutic nasal neuromodulation are disclosed herein. A targeted neuromodulation system configured in accordance with embodiments of the present technology can include, for example, an evaluation/modulation assembly at a distal portion of a shaft and including a plurality of electrodes. The electrodes are configured to emit stimulating energy at frequencies for identifying and locating target neural structures and detect the resultant bioelectric properties of the tissue. The system can also include a console that maps locations of the target neural structures. The evaluation/modulation assembly can then apply therapeutic neuromodulation energy in a highly tailored neuromodulation pattern based on the mapped locations of the target neural structures. Accordingly, the system provides therapeutic neuromodulation to highly specific target structures while avoiding non-target structures to reduce collateral effects.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: April 21, 2020
    Assignee: National University of Ireland, Galway
    Inventors: David Townley, Brian Shields, Ivan Keogh, Peter Dockery, Ian Stephen O'Brien, Martin O'Halloran, Emily Elizabeth Porter, Marggie Jones
  • Patent number: 10610675
    Abstract: Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: April 7, 2020
    Assignee: The Foundry, LLC
    Inventors: Mark E. Deem, Hanson Gifford
  • Patent number: 10603059
    Abstract: Disclosed embodiments include devices and methods for shaping, bending, and/or volumetrically reducing rigid cartilaginous structures, such as hyaline cartilage in the septum. In the case of septal cartilage, shaping, bending, or reducing the cartilage would be useful for reducing nasal obstruction or to improve the cosmetic appearance of the nose.
    Type: Grant
    Filed: February 10, 2017
    Date of Patent: March 31, 2020
    Assignee: AERIN MEDICAL INC.
    Inventors: Fred Dinger, Andrew Frazier
  • Patent number: 10595842
    Abstract: An access catheter provides access for a large bore stiff therapeutic catheter across the atrial septum from above via the superior vena cava. The access catheter has an expandable member that direct a delivery tube outwards in a radial direction to place a delivery tube opening into direct contact with the fossa ovalis. The braided expandable member allows blood flow to pass when it is expanded; the expandable member provides support against the opposite wall of the right atrium. A hollow dilator tube enters the delivery tube to form a tenting shape to the fossa and a guidewire is passed across the fossa ovalis. Standard procedure allows delivery of the therapeutic catheter over the guidewire.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: March 24, 2020
    Inventor: William Joseph Drasler
  • Patent number: 10575882
    Abstract: Distal tip designs for bone fixation devices are disclosed. In some embodiments, a system for bone fixation includes a delivery catheter having a proximal end and a distal end; an expandable member having a proximal region and a distal region, wherein the expandable member is releasably attached about the distal end of the delivery catheter at the proximal region of the expandable member; a distal cap attached to the distal region of the expandable member to seal the expandable member; a light conducting fiber; and a light-sensitive liquid; wherein the delivery catheter has an inner void for passage of a light-sensitive liquid into the expandable member to expand the expandable member and an inner lumen for passage of the light conducting fiber into the expandable member to cure the light-sensitive liquid inside the expandable member.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: March 3, 2020
    Assignee: IlluminOss Medical, Inc.
    Inventors: Gene P. DiPoto, Robert A. Rabiner, Jeffrey P. Brousseau, Anthony W. O'Leary, Chi Y. Wong, Augustus C. Shanahan, Nicholas Ferrer, John Unger
  • Patent number: 10561496
    Abstract: Disclosed herein are designs for improved inflatable structures for use during minimally invasive cardiovascular procedures. These inflatable structures facilitate the perfusion of blood through an anatomical structure, such as a heart valve, during the cardiovascular procedure. The inflatable structures are formed of a plurality of balloons arranged radially around a central location. The plurality of balloons form a lumen through which blood flows. Each balloon of the plurality is shaped or configured to stabilize the adjacent balloons, limiting their movement relative to each other. For example, some embodiments can feature balloons with a keystone shape that limits movement of the balloons inward toward the lumen. Some implementations can also include a support coil running through the lumen. The support coil holds enables the lumen to be open to perfusion even in the early stages of balloon inflation.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: February 18, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yidong M. Zhu, Erik Bulman, Baigui Bian, Sam Sok, Pu Zhou
  • Patent number: 10524827
    Abstract: A deployment mechanism of a tissue-removing catheter includes a socket member received in a catheter body that is capable of moving longitudinally therein, and a ball member extending distally from the distal end portion of the cutting element and operatively connected to the socket member. The ball member is constrained axially relative to the socket member and is capable of pivoting relative to the socket member for allowing pivoting of the cutting element relative to the socket when the cutting element is moved from a retracted position to a cutting position.
    Type: Grant
    Filed: March 27, 2017
    Date of Patent: January 7, 2020
    Assignee: Covidien LP
    Inventors: Benjamin Fruland, John Pedersen, Scott Petersen, Robert Van Pelt, Thomas McPeak
  • Patent number: 10524825
    Abstract: A constraining structure for use with a balloon catheter can include multiple longitudinal struts and multiple, sinusoidal shaped radial rings. The constraining structure can expand to form a pattern of channels including substantially square windows. The constraining structure can modify, restrict, and control a shape and/or size of the balloon when inflated. Inflating the balloon catheter within the constraining structure can provide nonuniform pressure on a vessel wall adjacent the balloon.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: January 7, 2020
    Assignee: TriReme Medical, LLC
    Inventors: Tanhum Feld, Eitan Konstantino
  • Patent number: 10500794
    Abstract: An object of the present invention is to provide a method of joining resin tubes, in which the degree of freedom of selecting a tube material is large, and further a defect such as stiffness and contraction at joining portions of the tubes is not developed. The method of joining resin tubes according to the present invention is a method of joining resin tubes so that a first tube is joined to a second tube, the first tube and the second tube each being made of synthetic resin, the method comprising: a surface activation step of activating each of a joining region of the first tube and a joining region of the second tube; and an adhesion step of adhering the joining region of the first tube obtained via the surface activation step with the joining region of the second tube obtained via the surface activation step to each other.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: December 10, 2019
    Assignee: Ushio Denki Kabushiki Kaisha
    Inventors: Fumitoshi Takemoto, Makoto Wasamoto, Shinji Suzuki
  • Patent number: 10493259
    Abstract: This disclosure describes embodiments of a kit and its constituent components which together form an apparatus in which fluid communication between a medical device's lumen and the surrounding environment is provided by a conduit cooperatively defined by the medical device and a tubular member into which the device is inserted. The medical device and tubular member are configured to fit together such that an outer surface of the distal region of the medical device cooperates with an inner surface of the tubular member to define the conduit between the side-port of the medical device and a distal end of the tubular member. The conduit is operable to be used for injecting fluid, withdrawing fluid, and measuring pressure, for example. Methods of assembling and using the apparatus are described as well.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: December 3, 2019
    Assignee: Baylis Medical Company Inc.
    Inventors: John Paul Urbanski, Krishan Shah, Gareth Davies, Mahmood Mirza, Naheed Visram, Amanda Hartley
  • Patent number: 10456160
    Abstract: Assemblies and methods for scoring a stenotic region within a vessel of a patient are disclosed. An assembly can comprise a scoring member and a deployment member. The scoring member can include an elongate push structure and a tubular, self-expanding scaffold. The elongate push structure can be positioned proximal of the self-expanding scaffold and, at its distal end portion, eccentrically coupled with a proximal end portion of the self-expanding scaffold. The deployment member can be removably positioned within a central lumen of the self-expanding scaffold and detachably engageable with a portion of the self-expanding scaffold. The self-expanding scaffold can be movable between a downsized configuration, when receiving axial tension from the deployment member, and an expanded configuration, in the absence of axial tension.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: October 29, 2019
    Assignee: Teleflex Innovations S.à.r.l.
    Inventor: Howard Root
  • Patent number: 10448972
    Abstract: Deployment devices include a locking mechanism configured to secure a medical device to the deployment device. Methods of operating a deployment device include securing a medical device positioned at least partially within at least one cannula of the deployment device with a locking mechanism and releasing the medical device and securing at least a portion of the at least one cannula of the deployment device with the locking mechanism.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: October 22, 2019
    Assignee: Custom Medical Applications Inc.
    Inventors: N. Sandor Racz, James Shoemake, Kevin Dean Joiner