Abstract: A system for removing embolic material from an intravascular site is disclosed. The system includes an elongate, flexible tubular body, having a proximal end, a distal end, and a tubular side wall defining at least one lumen extending axially there through; an axial restraint carried by the side wall and exposed to the lumen; a rotatable core wire extendable through the lumen, the core wire having a distal end; a limit carried by the core wire, the limit having a bearing surface for rotatably engaging the restraint; and an agitator tip on the distal end of the core wire. The limit and the restraint are engageable to permit rotation of the core wire but limit distal advance of the tip relative to the tubular body.

Abstract: A method and dissecting device are disclosed for treating a stenotic vessel. The method including inserting a first dissecting member into a subintimal space of a blood vessel and a second dissecting device configured to be received within a lumen within the first dissecting device and inserted into the blood vessel in a bent state; dissecting an inner side of the subintimal space from an outer side of the subintimal space over an entire circumference of the blood vessel with the first dissecting device; and removing the dissected inner side of the subintimal space and a stenotic region attached to the inner side of the subintimal space from the blood vessel.

Abstract: The present disclosure is generally directed to novel bead geometries that can provide improved sanding efficiencies in rotational atherectomy procedures. The abrasive elements disclosed herein may open stenotic lesions to diameters that are substantially larger than the maximum diameter of the abrasive element. In some embodiments, the abrasive elements may open stenotic lesions to diameters that are substantially larger than the maximum diameter of the sheath from which the abrasive element is delivered through. In some embodiments the abrasive elements are configured to expand when the abrasive elements are rotated at high speeds. In some embodiments, the abrasive elements have local centers of mass that are positioned at opposite diagonal ends. Accordingly, the abrasive elements disclosed herein may have improved sanding ranges, reduce treatment times, and prevent re-stenosis.

Abstract: A tissue-removing catheter includes a tissue-removing element operably connected to a drive shaft for rotation of the tissue-removing element about an axis of rotation in a cutting direction. The tissue-removing element is, in some embodiments, an integrally formed one-piece body. The tissue-removing element has a tissue-removing head that includes a plurality of shearing members spaced apart around the axis of rotation. Channels separate the plurality of shearing members and extend through the radially outer surface of the tissue-removing head. In some embodiments, the shearing members include respective wedge portions that hook and cleave tissue as the tissue-removing element rotates.

Abstract: A containing element is used to capture material in a blood vessel for removal. The containing element is positioned within a constraining catheter while it is advanced through the blood vessel. A filament is coupled to the containing element which assists in opening and/or closing the containing element.

Abstract: The present invention teaches the use of a disc shaped mesh intrasaccular occlusion structure with at least one coil arm, with optional supplemental hydrogel, which is designed to implement an endovascular treatment to facilitate saccular aneurysm treatment while ameliorating or eliminating aneurysm recurrence.

Abstract: A matter conveyance system is located within a catheter and transports thrombus from a proximal portion of the catheter to a distal end of the catheter. In one example, the matter conveyance system is a screw or helix that rotates to cause movement of the thrombus.

Abstract: The present disclosure provides an articulation joint that can include a plurality of articulation links, wherein each articulation link can include an elongate body having a proximal end, a distal end, an outer surface, and a first lumen extending from the proximal end to the distal end. Each articulation link can further include a plurality of arms extending radially outward from the elongate body, wherein each arm includes an inner end attached to the outer surface of the elongate body and a second lumen extending from a proximal side of the arm to a distal side of the arm. The articulation joint can also include a bending member positioned within the first lumen of the elongate body and a control member positioned within a plurality of second lumens, wherein each of the plurality of second lumens includes a common longitudinal axis.

Abstract: A surgical instrument including a reusable and sterilizable hub assembly and a releasably connectable disposable blade assembly allows multiple reuse of the hub assembly in conjunction with single use disposable blade assemblies.

Abstract: Atherectomy catheters and methods of using them are described herein. In particular, described herein are optical coherence tomography (OCT) catheters that may include a distal tip that can be deflected away from the long axis of the device using a multi-channel bushing. The bushing may include at a hinge point that is offset (e.g., located on a side of the elongate body near the distal end of the elongate body) and a rotatable cutter near an imaging assembly that can be driven against the wall with a high mechanical advantage.

Abstract: Balloon angioplasty catheters having cutting or scoring members that are moveable in at least one direction between a stowed position (away from the angioplasty balloon) and an operative position (on the angioplasty balloon). A balloon catheter of the present invention alternately useable to perform balloon dilation of a body lumen with and without concurrent cutting or scoring.

Abstract: The present invention provides an atherectomy catheter which has a cutting element that is able to cut both soft tissue and hard tissue, and methods of cutting material from a blood vessel lumen using a rotating cutting element. The cutting element has a sharp cutting edge that surrounds a cup-shaped surface and at least one surface of abrasive material. The cup-shaped surface directs the cut material into a tissue chamber. The cutting edge and the cup-shaped surface together are well suited to cut and remove relatively soft tissue from the blood vessel. The abrasive material surface in combination with the cutting element is well suited to abrade and remove hard material from the blood vessel.

Abstract: The present disclosure relates to a mechanical thrombectomy device that includes a catheter assembly with a basket assembly formed of a proximal hub and a distal hub; a flexible tube having a first end attached to the proximal hub and a second end attached to the distal hub; and a plurality of basket wires. The flexible tube may be laser-cut to allow for bending, elongation, and compression. The basket wires each have a first end attached to the proximal hub and a second end attached to the distal hub. The basket wires are disposed around the flexible tube and configured to expand to a preset shape. The basket assembly is attached to a distal end of a rotatable shaft. A drive assembly is configured to rotate the rotatable shaft to rotate the basket assembly. The basket assembly when rotated is configured to macerate a material proximate to the basket assembly.

Abstract: An atherectomy catheter includes an elongate flexible catheter body, a cutter near the distal end of the catheter body, a drive shaft connected to the cutter and extending within the catheter body, an imaging element near the distal end of the catheter body and an imaging shaft connected to the imaging element and extending within the catheter body. The cutter and the imaging element are mechanically isolated, and the drive shaft is configured to be axially translated relative to the imaging shaft and the catheter body.

Abstract: Devices and methods for trimming a stent to a desired length with an outer tube and an inner tube having a distal end and a diameter configured to receive a portion of the stent in excess of the desired length. The inner tube may move within the outer tube and the distal end may include an end effector configured to trim the portion from the stent while the device and stent are within a patient.

Abstract: A tissue-removing catheter includes a catheter body and a tissue-removing head. The catheter body has an annular shearing blade at the distal end thereof. The tissue-removing head is at the distal end of the catheter body and is configured to rotate about an head axis relative to the catheter body, and reciprocate along the head axis relative to the catheter body between proximal and distal positions.

Abstract: A tissue-removing catheter includes a tissue-removing element operatively connected to a drive shaft for rotation of the tissue-removing element about an axis of rotation in a cutting direction. In some embodiments, the tissue removing element has a cutting blade and cutting teeth positioned radially inward of the cutting blade with respect to the axis of rotation. The cutting blade and cutting teeth are fixed with respect to one another to form first and second cuts in tissue as the tissue-removing element rotates. In certain embodiments, the tissue-removing element includes a cutting blade and raised elements spaced apart inward of the cutting blade relative to the axis of rotation to define an annular tissue-receiving channel between the cutting blade and the raised elements. A bottom surface of the channel can define cutting teeth.

Abstract: An apparatus is provided for use in combination with a surgical sponge assembly and a trocar including a cannula where the surgical sponge assembly includes a suction tube coupled to a sponge head. A body includes a proximal end, a distal end, and a first lumen and a second lumen that join one another to form a cavity. The first lumen and the second lumen are separated from one another by an interior wall that extends from the proximal end of the body to the cavity. The first lumen is sized and configured to allow an axial movement of the suction tube within the first lumen and the cavity is configured to store at least a portion of the sponge head. The apparatus is configured to allow the surgical sponge assembly to be moved from a retracted position to an extended position.

Abstract: An embolectomy device comprised of an expansion unit and a support unit is disclosed. The expansion unit can be actuated in response to one or more external stimuli, and the support unit, located proximately to the expansion unit, provides a force to hold the expansion unit in place and to further induce the expansion unit's radial expansion. The radial expansion of the expansion unit causes the expansion unit to physically contact a blood clot, enabling the blood clot to be removed. In some embodiments, the expansion unit can be fabricated from a shape memory polymer foam. In some embodiments the support unit can be fabricated from any elastic material including, without limitation, shape memory alloys.

Abstract: A dissecting device for dissecting tissue surrounding a blood vessel in a living body. The dissecting device includes a grasping section that includes an insertion lumen. The dissecting device includes a dissecting member at the distal portion of the grasping section. The dissecting member is insertable into the living body along the blood vessel to dissect the tissue surrounding the blood vessel in the living body. The dissecting member includes a treating section and a protruding section. The treating section performs a predetermined treatment of a branch vessel branching from the blood vessel. The protruding section protrudes from the treating section in the thickness direction of the treating section. The protruding section includes a guide section configured to guide the branch vessel toward the treating section.

Abstract: A tissue-removing catheter includes an elongate body having proximal and distal end portions and a motor fixed to the distal end portion of the elongate body. A tissue-removing element is mounted on the motor to be driven in rotation by the motor about a drive axis. In some embodiments, the tissue-removing element includes a receptacle that receives the motor therein. The tissue-removing element can include a distal tip that extends distally beyond the motor to define the distal end of the catheter. The motor can be controlled using an actuator located outside the body. And in some embodiments, use of the catheter involves adjusting the rotational speed of the tissue-removing element using the actuator.

Abstract: Embodiments of the invention relate to coring tip or beak designs for single insertion, multiple sample, multiple lesion tissue coring and acquisition (biopsy or excisional) medical devices to facilitate tissue penetration, coring, capturing and parting off of tissue that also inherently enhance ultrasound images for the purpose of continuous and positive excisional device tip visualization for targeting and capture of target tissue, such as lesions or other tissue in the body.

Abstract: A serration balloon can have a number of different components and can be made in a number of different manners. One or more longitudinally extending members with periodic raised wedges can be attached to a medical balloon. They can be attached with a fiber coating, a polymer coating, or other methods. A polymer matrix can be used to bond the longitudinally extending member to the surface of the balloon. The fiber coating can be, for example, a thread or mesh that secures the longitudinally extending member to the balloon. The medical balloon can be an angioplasty balloon, such as an off-the-shelf angioplasty balloon.

Abstract: A wire for use with a vascular treatment device may have a proximal end, a distal end, and a main shaft extending therebetween. The distal end may have a distal free end and a first segment. The first segment may extend from the main shaft and may be biased to a first included angle that is defined between the main shaft and the first segment and less than 180 degrees.

Abstract: Components and corresponding systems are described for providing removal of a clot or fragment thereof to address an acute ischemic stroke condition. In particular, a filter design is presented that provides metal elements below a bundle of polymer fibers to provide more mechanical strength while cushioning the vessel wall from direct contact with the metal elements. Designs of stent retrievers are presented with polymer covers or mounted on the exterior of a microcatheter. Corresponding systems are described that can use various combinations of the components, generally in combination with an aspiration catheter. Corresponding procedures are described that can effectively use the various devices and systems.

Abstract: Medical devices and methods for using medical devices are disclosed. A rotational atherectomy device may include an elongate shaft having a proximal end region, a distal end region and a lumen extending therein. The medical device may also include a cutting member positioned adjacent the distal end region of the elongate shaft. The cutting member may be radially expandable. The medical device may also include a sizing member positioned adjacent the cutting member. The sizing member may be radially expandable, and the radial expansion of the cutting member may be limited by radial expansion of the sizing member.

Abstract: This set comprising: an anatomic articulating member, having a concave articulating surface intended to articulate with a complementary humeral implant and having an anatomic coupling feature, a reversed articulating member, having a convex articulating surface intended to articulate with a complementary humeral implant and having a reversed coupling feature that is shaped differently from the anatomic coupling feature, and an anchorage member intended to be anchored in a human glenoid, the anchorage member including a body which defines a proximodistal axis and has inner bore extending along the proximodistal axis, the body being provided within the inner bore with both an inner first feature that is designed to cooperate with the anatomic coupling feature when the anatomic coupling feature is introduced within the inner bore, so as to fixedly couple the anchorage member with the anatomic articulating member, and an inner second feature that is designed to cooperate with the reversed coupling feature when

Abstract: Devices for restoring blood flow to facilitate lysis of clots and/or enable capture of clots are disclosed. The devices can be configured to be disposed within a lumen of a microcatheter that is inserted within neurovasculature above a carotid siphon to a location of a clot. The devices can include an elongate pusher member and a self-expandable capturing member coupled to a distal end of the elongate pusher member. The capturing member can comprise a generally cylindrical body having an cell structure that is configured to compress the clot against an inner wall of the neurovasculature and capture the clot at least partially on a surface of the generally cylindrical body upon deployment of the capturing member from the microcatheter, thereby restoring blood flow to the neurovasculature downstream of the clot.

Abstract: A rotatable cutter for a tissue-removing catheter includes a central hub, flutes spaced apart from one another around the circumference of the central hub, and arcuate cutting members. Each cutting member includes an arcuate cutting edge extending along an arc length of the cutting member for cutting tissue as the cutter is rotated. A raised element of each cutting member has a leading cutting edge at a leading end of the distal cutting member for cutting tissue as the cutter is rotated. A clearance portion of each cutting member is recessed, relative to the longitudinal axis of the cutter, from the raised element and extends from the raised element to a trailing end of the cutting member to provide clearance for the leading cutting edge of an adjacent and opposing distal cutting member.

Abstract: A rotational atherectomy device advanceable over a guidewire. The rotational atherectomy device includes a drive shaft rotatably extending through an outer tubular member to rotate a cutting member positioned at a distal end thereof. The rotational atherectomy device further includes an insert positioned within the cutting member for frictional contact with the guidewire.

Abstract: A cannula ingress system may include a tip stabilization mechanism having a tip stabilization mechanism distal end and a tip stabilization mechanism proximal end, a fixation mechanism, a hypodermic tube having a hypodermic tube distal end and a hypos dermic tube proximal end, and a tip having a tip distal end and a tip proximal end. The tip may be disposed within the hypodermic tube wherein the tip distal end extends from the hypodermic tube distal end. The fixation mechanism may be disposed within a fixation mechanism channel of the tip stabilization mechanism. The tip stabilization mechanism may be disposed over the tip and the hypodermic tube distal end.

Abstract: An artificial airway sputum scab cleaner including a connection hub, a display window, a detection tube, a sputum suction tube, a sputum suction device, a probe head a hooking device, a light beam device and a camera device; the hooking device includes a hooking channel, a hooking spoon, a push rod and a permanent magnet, an iron sheet, a first coil.

Abstract: According to an aspect of some embodiments of the present invention there is provided a device for removal of obstructive material from a vessel comprising: an expandable structure sized for insertion into the vessel; and one or more portion protruding radially from a central longitudinal axis of the expandable structure such that a space between the protrusion and a closest portion of the expandable structure to the portion includes a radial component; wherein the space is sized and shaped to be suitable to accept obstructive material.

Abstract: Systems and methods can remove material of interest, including blood clots, from a body region, including but not limited to the circulatory system for the treatment of pulmonary embolism (PE), deep vein thrombosis (DVT), cerebrovascular embolism, and other vascular occlusions.

Abstract: This document describes rotational atherectomy devices and systems for removing or reducing stenotic lesions in blood vessels by rotating an abrasive element within the vessel to partially or completely remove the stenotic lesion material.

Abstract: An adjustable containment shield is operable to mount on an output housing of a surgical instrument. The shield includes a substantially transparent body including a distal face, a proximal face opposite the distal face, a generally consistent thickness defined between the distal face and the proximal face such that the body is pliable and resilient, a mounting hole defined in the body to engage the output housing, and a plurality of folds to allow the shield to move from a retracted position to an expanded position. When mounted on the output housing, the distal face is at an acute angle with respect to a longitudinal axis through the mounting hole and face is also facing toward a patient engagement end of the surgical instrument. The proximal face is at an obtuse angle with respect to the longitudinal axis and facing toward a housing side of the surgical instrument.

Abstract: A clot retrieval device for removal of occlusive clot from a blood vessel comprises a clot engaging element 700 having a constrained delivery configuration and an expanded deployed configuration. In the expanded configuration peripheral portions are laterally spaced-apart and the clot engaging section 700 extends between the peripheral portions. The device 700 may have two superimposed wave patterns provided by a large amplitude curve 723 and shorter pitch sinusoidal patterns 721, 722. A wave shape varies the contact pressure between a clot and the device along the length of the device, reducing the compression of the clot by the device at some locations. The device can elongate when placed under tension which aids elongation of the clot during dislodgement.

Abstract: A medical device includes an expandable-and-contractible member capable of radially expanding and radially contracting, an incising member disposed on an outer circumference of the expandable-and-contractible member and having a hollow portion, a core wire inserted in the hollow portion, a distal tip, and a ring. The core wire is capable of sliding in a longitudinal direction of the medical device as the expandable-and-contractible member expands or contracts. The incising member is therefore not likely to come off upon radial expansion or radial contraction of the expandable-and-contractible member, and is therefore not likely to interfere with the expanding or contracting movement of the expandable-and-contractible member.

Abstract: Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.

Abstract: This document describes rotational atherectomy devices and systems for removing or reducing stenotic lesions in blood vessels by rotating an abrasive element within the vessel to partially or completely remove the stenotic lesion material.

Abstract: An anchor device to simplify catheterization procedures, particularly for insertion and maneuvering of large catheters in tortuous arteries, vessels, or other lumen is disclosed. In some embodiments, the anchor device includes an anchor stent formed from a plurality of zig-zag shaped wire elements that are coupled together. The device further includes a plurality of connector struts attached at a proximal end of the anchor stent, the connector struts coalescing to form a strut tip. A guide device, such as a guidewire, is attached to the anchor stent at the strut tip and may be used to guide the anchor stent into the arteries or other vessels and toward a target treatment site.

Abstract: A tissue-removing catheter includes a tissue-removing element operably connected to a drive shaft for rotation of the tissue-removing element about an axis of rotation in a cutting direction. The tissue-removing element includes a cutting edge that extends around the axis of rotation and a depth stop that extends around the axis of rotation radially inward of the cutting edge relative to the axis of rotation. The depth stop defines an engagement surface adapted to engage a hard object and thereby limit the depth at which the cutting edge cuts into the hard object. In use, when the cutting edge cuts into a hard object, the depth stop engages the hard object to limit the cutting depth.

Abstract: An elongate tool with a cutting end. In some embodiments the end is bendable. Optionally, the end is bendable between two cutting edges. Optionally or alternatively, the end includes both a forward cutting edge and a side cutting edge. The tool may be sized for hand-held use, with control from outside the body, for treating a spinal stenosis.

Abstract: A medical device for collecting a solid object together with a fluid in a living body, including: a cylindrical member having an inner cavity, a suction port provided on the distal end of the inner cavity, and a discharge port on a side wall and communicating with the inner cavity; an impeller in the inner cavity configured to carry the fluid from the suction port to the discharge port; and a filter in the inner cavity configured to collect the solid object. At least part of the wall surface of the cylindrical member, which defines a flow channel allowing movement of the fluid from the impeller to the discharge port, is inclined from a center axis of the cylindrical member toward a distal end with respect to a transverse direction of the cylindrical member.

Abstract: The present system is directed in various embodiments to rotational atherectomy systems and methods generally. More specifically, a method for methodically softening and disrupting calcification within the wall of a biological conduit or lumen. This result is achieved by use of at least one eccentric head that, during high-speed rotation within the exemplary lumen, produces a combination of a low-frequency orbital motion comprising a force that is exerted against the lumen wall, with concomitant deflection of same, and a high-frequency pulsatile frequency, also with concomitant exertion of force against the lumen wall and deflection of same. These force-driven deflections produce shockwaves within the layers of the exemplary artery's wall layers, resulting in systematic disruptions of any calcification within the intimal and/or medial layers of the subject artery. In addition, any calcification within the occlusion is also softened and disrupted, increasing compliance of the vessel and/or lesion.

Abstract: A tissue-removing catheter for removing tissue from a body lumen includes a tissue-removing element. The tissue-removing element may be coupled to a first longitudinal body portion of the catheter body. The first longitudinal body portion may be rotatable along its length and relative to a second longitudinal body portion to adjust the angular position of the first longitudinal body portion relative to the second longitudinal body portion. An angular-positioning mechanism may be operatively connected to the tissue-removing element for rotating the tissue-removing element relative to the second longitudinal body portion about a rotational axis to adjust an angular tissue-removing position of the tissue-removing element, relative to the longitudinal axis of the body lumen, from a first angular tissue-removing position to a second angular tissue-removing position offset from the first angular tissue-removing position.

Abstract: The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal. The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

Abstract: A device includes a first end portion, a second end portion, an intermediate portion, and a graft material. The first end portion has a first end diameter. The second end portion has a second end diameter smaller than the first end diameter. The first end portion comprises a first material. The second end portion comprises a second material different than the first material. The intermediate portion is between the first end portion and the second end portion. The intermediate portion tapers between the first end portion and the second end portion. The graft material is coupled to at least the intermediate portion.

Abstract: A surgical bur is disclosed having cutting and trailing edges and associated flutes and lands. Each flute includes a cutting edge. Each of the trailing edges relatives in a selected dimension to a preceding cutting edge.

Abstract: A medical device for incising a substance inside a biological lumen. The medical device includes a tubular drive shaft that is rotatable, an intermediate portion connected to the drive shaft, at least one strut interlocked with the drive shaft, a tubular linear motion shaft inside of the drive shaft, and a tubular interlock portion. The strut is rotatable with the drive shaft and is expandable radially outward in response to outward expansion of the intermediate portion. The linear motion shaft is movable relative to the drive shaft in the axial direction to cause the strut to expand radially outward. The tubular interlock portion interlocks the drive shaft and the linear motion shaft while maintaining liquid-tight properties. The tubular interlock portion is stretchable in the axial direction.