Abstract: An aspect of the present disclosure may include an apparatus having an optical waveguide. The optical waveguide may have a distal end surface non-normal to a longitudinal centerline of a distal end portion of the optical waveguide, wherein the distal end surface may define a portion of an interface configured to redirect electromagnetic radiation propagated from within the optical waveguide and incident on the portion of the interface to a direction offset from the longitudinal centerline. The apparatus may further include a capillary component which may have a first portion of an inner surface heat-fused to a portion of an outer surface of the optical waveguide.

Abstract: Methods and apparatus for the inactivation of infectious agents in, on or around a catheter residing in a patient's body cavity. The method comprises transmitting non-ultraviolet sterilizing electromagnetic radiation (EMR) substantially axially along an optical element in the catheter body. Through delivery of the sterilizing EMR to particular areas of highest infection, the present disclosure is able to inactivate the major sources of infection in catheters.

Abstract: A medical device is provided. The medical device includes a puncture needle that is inserted into body tissue from outside a body and pierces membranous tissue near pulsating tissue inside the body tissue; a tubular protection member that is disposed on the outer side of the puncture needle; a pulse-information acquisition portion that acquires pulse information of the pulsating tissue; and a driving unit that moves the puncture needle and the protection member relative to each other in synchronization with the pulse information of the pulsating tissue acquired by the pulse-information acquisition portion, in such a manner that a tip of the puncture needle is retracted toward a proximal end from a distal end of the protection member when the pulsating tissue expands and that the tip of the puncture needle is projected farther forward from the distal end of the protection member when the pulsating tissue contracts.

Abstract: An orthopedic infra-red laser medical device and methods of use for applying infra-red energy to an anatomic region of interest located within the body of a patient. The device includes a hollow needle and a housing on which the needle is releasably mounted. The housing includes an infra-red laser source for producing a laser beam and directing the beam through the needle to exit out of the open distal end of the needle. The distal end of the needle is sharp to pierce through the skin of the patient to a position closely adjacent the anatomic region of interest to deliver the infra-red laser beam thereto without any intervening skin and tissue attenuating the infra-red laser beam. The device can be used for various orthopedic purposes and can also be used on fat in a patient to release activated stem cells.

Abstract: An apparatus, system and method for re-canalization or opening a passage through an occlusion in a blood vessel is disclosed. The apparatus and method, which are appropriate for both cardiovascular as well as peripheral vessels, use hydraulic pressure to drive a vibratable member, and the system includes a control unit to permit the frequency or amplitude of oscillation of the vibratable member to be adjusted to suit the morphology or hardness of the target occlusion. Also disclosed is a method for adjusting the force of vibration.

Abstract: In various embodiments, wavelength beam combining laser systems incorporate optical cross-coupling mitigation systems and/or engineered partially reflective output couplers in order to reduce or substantially eliminate unwanted back-reflection of stray light.

Abstract: A photoacoustic diagnostic apparatus is provided. The photoacoustic diagnostic apparatus includes a movement restriction unit that selectively restricts a location movement of a user input unit that receives an input signal from a user for a light irradiation unit to irradiate light, based on a location of a contact detection unit that detects whether a probe contacts a subject to be imaged.

Abstract: A system for ablation of tissue has at least a guideplate having a front surface and a rear surface. The guideplate has multiple guideholes distributed over the front surface and passing from the front surface to the rear surface. The at least three longitudinally advancing laser emitters are on elongated supports. The at least three longitudinally advancing laser emitters on elongated supports have a diameters that allow their passage through the guideholes on the guideplate. Each of the three laser emitters has a projection area for emission of laser energy; and the projection areas for each of the three laser emitters overlapping only a portion of the projection areas for at least two others of the three laser emitters when the at least three laser emitters lie within a single geometric plane. Moving the laser emitters while active devascularizes changing volumes of tumor tissue.

Abstract: A method of treating mammalian skin tissues for causing a predetermined physiological change in the mammalian skin tissues. A treatment composition of matter is applied onto the mammalian skin. The mammalian skin is irradiated with a first pulse having a power density above an activation threshold power density and with a second pulse. The first pulse is emitted for a duration of from about 1 femtosecond to about 1 hour, and the first pulse is separated from the second pulse by an inter-pulse interval of from about 1 microsecond to about 10 seconds. The treatment composition of matter includes a photoreactive substance and is applied in an amount sufficient to cause physiological changes within the mammalian skin tissue upon the mammalian skin tissue being irradiated.

Abstract: System and methods for channeling a path into bone include a trocar having a proximal end, distal end and a central channel disposed along a central axis of the trocar. The trocar includes a distal opening at the distal end of the trocar. The system includes a curved cannula sized to be received in the central channel, the curved cannula comprising a curved distal end configured to be extended outward from the distal opening to generate a curved path extending away from the trocar. The curved cannula has a central passageway having a diameter configured to allow a treatment device to be delivered through the central passageway to a location beyond the curved path.

Abstract: An intraocular shunt can be placed into a human eye using a hollow shaft having a distal tip with a bevel. The hollow shaft can be advanced through the anterior chamber while the hollow shaft holds the intraocular shunt. The sclera can be penetrated with the beveled distal tip until all of the bevel is positioned distal to a distal wall of the sclera. The shunt can be advanced at least partially from the hollow shaft into a drainage space of lower pressure than the anterior chamber. The hollow shaft can be withdrawn from the eye, leaving the shunt extending from the anterior chamber completely through the sclera to the drainage space.

Abstract: An improved method and device is provided for safe and efficient low power density endoluminal treatment of venous insufficiency. One such device emits pulsed or continuous energy radially through an optical fiber end with a conical shaped tip for 360° radial emission. In some embodiments, a conical reflective surface is distally spaced opposite to and faces the emitting tip for enhancing radial emission efficiency by reflecting out any designed or remnant forwardly transmitted energy in radial directions. Other devices include flat emitting faces sealed within protective, radiation transparent covers. Laser radiation is transmitted at a wavelength and power such that is it substantially entirely absorbed within the blood vessel wall to sufficiently damage the intravascular endothelium and, in turn, achieve blood vessel closure.

Abstract: Herein is disclosed an optical device for directing electromagnetic radiation and a means for manufacturing the same. The optical device can include a total-internal-reflection (TIR) element which includes a TIR surface; a TIR protective cap fused about the TIR element, thereby providing a liquid-free volume between the TIR surface and an internal surface of the TIR protective cap; a sleeve element fused to a portion of the TIR protective cap, thereby providing at least one fluidic pathway between the sleeve element and the TIR protective cap, the at least one fluidic pathway adapted to carry a stream of a cooling fluid through the optical device during use; and an optical pathway from the TIR surface to an external surface of the sleeve element; where any of the at least one fluidic pathway does not cross the optical pathway.

Abstract: Catheters are provided which have a high capacity of axial (pushability) and rotational (torquability) movement with relative maximum flexibility and which, at the same time have the ability to adapt to at least partial variations of diameter under the thrust of other catheters or dilators travelling though the lumen or so as to flatten itself at least partially to travel through the lumen of other catheters, such as for example feed catheters.

Abstract: In various embodiments, wavelength beam combining laser systems incorporate optical fibers and partially reflective output couplers or partially reflective interfaces or surfaces utilized to establish external lasing cavities.

Abstract: In order to sufficiently cauterize a target site existing in a deep portion of a cardiac muscle tissue even in the case where the fat layer attached to an epicardium is thick or where the cardiac muscle is thickened due to cardiac hypertrophy and the like, provided is an ablation catheter comprising: an elongated catheter main body; an electrode for ablation placed in a leading end part of the catheter main body; and an optical fiber that is placed along a longitudinal direction of the catheter main body, includes an emission end formed on a leading end surface of the catheter main body, and emits a laser beam guided therethrough from the emission end.

Abstract: A method of treating glaucoma in a human eye by inserting a distal exit port of a cannula at least partially into Schlemm's canal of the eye; delivering a dye through the cannula into Schlemm's canal; identifying obstructions within Schlemm's canal; and delivering an ocular implant through the cannula into Schlemm's canal.

Abstract: A catheter enables real-time light measurements, for example, without limitation, diffuse reflectance, fluorescence, etc., from biological materials, such as tissue (including blood), while performing RF ablation. The catheter tip design isolates illumination and collection paths within the tip electrode such that light for illuminating the tissue of interest (e.g., cardiac tissue or blood) is isolated within the tip electrode from light that returns from the tissue to the catheter tip, and vice versa. Such a design advantageously avoids saturation of the optical detector, and ensures diffusion of the illumination light within the medium of interest. The catheter has a catheter body and a tip electrode with a shell wall and a hollow cavity. The shell wall has at least an illumination opening and a collection opening.

Abstract: A dental curing light system is configured to include a dental curing light (100) having a device body (102) with a proximal handle portion (106) and a distal head portion (104). One or more light sources (120) for generating light are disposed on or within the device body (102). Generated light is emitted from the distal head portion (104) and includes wavelengths greater than about 420 nm and wavelengths less than 420 nm. A separate head attachment member or device (160) is coupleable over the distal head (110) of the device body (102) so as to receive substantially all light emitted from the distal head portion (104) of the device body (102).

Abstract: A dilator retractor and the dilators that are used for minimally invasive spinal surgery or other surgery are configured to accommodate the anatomical structure of the patient as by configuring the cross sectional area in an elliptical shape, or by forming a funnel configuration with the wider end at the proximate end. In some embodiments the distal end is contoured to also accommodate the anatomical structure of the patient so that a cylindrically shaped, funnel shaped, ovoid shaped dilator retractor can be sloped or tunneled to accommodate the bone structure of the patient or provide access for implants. The dilator retractor is made with different lengths to accommodate the depth of the cavity formed by the dilators.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.

Abstract: Systems, methods, and other embodiments associated with tracking an ablative device and monitoring an ablation produced by the ablative device are described. One example method includes acquiring a magnetic resonance (MR) image of an ablative device inserted in a body and selectively controlling positioning of the ablative device based, at least in part on the MR image. The MR image may be continuously provided in real-time by an interventional MR imaging apparatus programmed to image using a tri-orthogonal plane sequence. The method may also include acquiring an MR image of an ablation performed by the ablative device, and selectively controlling the ablative device based, at least in part, on the MR image. The MR image may also be provided by the IMRI apparatus operating according to a tri-orthogonal plane sequence. In one example, the ablation may treat hypopharyngeal obstructive sleep apnea by reducing tongue base volume.

Abstract: An ablation cannula kit with insert includes a trocar and cannula with a hollow shaft. The hollow shaft is configured to permit passage of the trocar therethrough. An auxiliary port extends from an exterior surface of the cannula and defines a hollow passageway into the hollow shaft. Notably, an insert is included in the kit. The insert defines a hollow shaft and is adapted to be inserted into the hollow shaft of the cannula. An auxiliary port extends from an exterior surface of the insert defining a hollow passageway into the hollow shaft of the insert. Finally, a laser fiber is included with a diameter less than an interior diameter of the hollow shaft of the insert so as to permit passage of the fiber through the hollow shaft of the insert.

Abstract: A method and device for stimulating human dermal tissue retraction and collagen and elastin production is provided. One or more lasers or other electromagnetic radiation devices produce at least two output beams (split or independent beams) that can be directed to deliver electromagnetic energy to a desired subsurface depth of dermal tissue, thereby disrupting the same, without causing excessive damage to the adjacent epidermis, subcutaneous fatty tissue, or blood vessels of the skin.

Abstract: The invention relates to a laser handpiece 1, an exchangeable fiber-optic insert 10, and a control unit 70 therefor. The laser handpiece 1 comprises a optical waveguide 35, which is connected to a light coupling site in a base member 21 and in which the application element 10 for laser light is exchangeably attached to the base member 21. The base member 21 is mounted in a sleeve-type grip 3 for axial displacement therein. The light guide 10 can be wound around a control device 70 which has an annular gap 73 for this purpose and a lower housing part 75 which is offset from an upper housing part 74. An exchangeable fiber-optic insert 10, 27 acting as an application element is provided with a sleeve 80 serving as protection during transportation and as an assembling tool.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.

Abstract: Embodiments of a laser ablation system include a shaft, a balloon and a laser fiber. The shaft has a proximal end and a distal end. The balloon is attached to the distal end of the shaft, a portion of which is disposed within the balloon. A light dispenser at a distal end of the laser fiber is configured to deliver laser light through the balloon. A central axis of the balloon is aligned with a longitudinal axis of the shaft. The balloon has a variable transparency such that the transmission of laser light through the balloon is non-uniform along the central axis. Accordingly, an energy of laser light transmitted from the light dispenser through the balloon to the targeted tissue varies due to the variable transparency of the balloon.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.

Abstract: The present invention relates to a light guide unit for a laser applicator, wherein the light guide unit has a light guide tip assembly removably insertable into the laser applicator, wherein the light guide tip assembly comprises an optical fiber and a coupling member provided on a proximal end of the optical fiber. When the coupling member is provided on the optical fiber, a proximal end face of the optical fiber needs to be kept clean. It is also desired that the light guide tip assembly can be manufactured easily. It is suggested to provide the coupling member via a casting technique.

Abstract: Embodiments of a medical device and related methods of use are provided for extracting tissue. The device may include an elongate member having a proximal end and a distal end. Two or more channels may extend through the elongate member from the proximal end to the distal end, and a morcellating device may be included in one of the channels. In addition, one of the channels may be configured as a return channel for extracting the morcellated tissue.

Abstract: In vivo hyperthermia treatment of a target tissue can include imaging the target tissue with a magnetic resonance imaging (MRI) system, positioning a hyperthermia treatment probe in or proximate to the target tissue based on the imaging, and heating the target tissue by the probe. During the heating, changes in temperature of a volume of tissue that includes the target tissue can be monitored with the MRI system to determine an amount of the heating applied to the target tissue, and the heating can be terminated when the amount of the heating reaches a predetermined amount.

Abstract: A method comprises providing a balloon catheter device; locating a balloon portion within a paranasal sinus ostium while the balloon portion is in the first position such that a distal end of the balloon portion is at a distal end of a paranasal sinus ostium; inflating the balloon portion while the balloon portion is located in the paranasal sinus ostium such that at least a portion of the paranasal sinus ostium is dilated; sliding the balloon portion back to a second position while leaving the distal end of a guide member at the distal end of the paranasal sinus ostium; and viewing an image provided by a camera to determine whether an entirety of the paranasal sinus ostium has been dilated.

Abstract: A prostate therapy system is provided that may include any of a number of features. One feature of the prostate therapy system is that it can access a prostate lobe from the urethra. Another feature of the prostate therapy system is that it can deliver condensable vapor into the prostate to ablate the prostate tissue. Another feature of the prostate therapy system is that it can aspirate tissue from the prostate. Yet another feature of the prostate therapy system is that it can rotate during delivery of vapor and aspiration of tissue. Methods associated with use of the prostate therapy system are also covered.

Abstract: Lysing of fat cells in adipose tissue beneath the skin and liquefying the released fat is achieved by introducing a side-firing thermal energy device into the tissue to be irradiated, while thermal energy, such as laser energy, is emitted at a selected level for a selected period of time, depending on the volume to tissue to be irradiated. The side firing device is advanced into tissue and withdrawn and, while energy is emitted, is aimed separately at 3 o'clock and 9 o'clock and, is repetitively rotated through an arc of about 120°, producing a bowtie-shaped irradiation pattern. The side firing device may be centered and sealingly held in position in a liposuction cannula by ribs extending inwardly from the interior of the liposuction cannula. At least one of the ribs has a channel for infusion of an irrigating liquid.

Abstract: An illumination and laser energy delivery system, including an extended tip laser and illumination probe for retinal surgery, is disclosed that allows efficient delivery of laser and illumination energy to a surgical site through a device that is smaller than the standard 20 gauge probe conventionally used in endo-photocoagulation procedures. Novel constructions, as disclosed, enable the space inside the probe cannula to be used more efficiently than in prior art devices, providing improved performance of the device and system in delivering laser and illumination energy to the surgical site.

Abstract: A system and method are provided for minimally-invasive selective removal of fat from a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength excites the nanoparticles to melt fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, a housing sleeve disposed in an inner bore of the handle configured to project a distance from the handle distal end, an optic fiber disposed in the housing sleeve, a shape memory sleeve disposed over a distal end of the optic fiber, and a light source configured to connect to a proximal end of the optic fiber. The shape memory sleeve may be configured to curve the distal end of the optic fiber at an angle, e.g., 90 degrees, when the shape memory sleeve is not contained within the housing sleeve.

Abstract: Provided is an optical fiber for producing heat wherein a reflection tube (13) is wrapped on its outer peripheral surface by a heat conduction tube (14) to block laser beam from being irradiated outside, and a plurality of grooves are formed on a side of an optical fiber (11) so as to transmit laser beam to the side of the optical fiber (11) at 360° around a central axis of the optical fiber (11) where a cloth (12) is peeled away such that the area where heat is produced is expanded to a whole length direction of the optical fiber (11) where the cloth (12) is peeled away between the optical fiber (11) and the reflection tube (13).

Abstract: A skin surface is treated with RF energy (e.g., unipolar, monopolar, bipolar or multipolar RF delivery). A first semiconductive cap disposed on a first distal end of a first electrode and, optionally, a second semiconductive cap disposed on a second distal end of a second electrode are applied to the skin surface. RF energy is delivered from the first electrode and the second electrode through the first semiconductive cap and the second semiconductive cap, respectively, through the skin surface. The first semiconductive cap and/or the second semiconductive cap have an electrical conductivity matched or substantially matched to the skin's electrical conductivity (e.g., about 0.1 to about 2 times that of the skin).

Abstract: Methods for dissecting tissues are provided. The methods comprise selecting a tissue site comprising dermis and subdermal fat connected to the dermis, and applying ultrasonic energy to the tissue to remove at least a portion of the subdermal fat from the dermis, wherein the ultrasonic energy is applied to minimize damage to the dermis.

Abstract: An endoscope for an optical fiber provides for inflow and outflow of irrigant. A telescope is included having a field of view directed into a working region. The endoscope defines a “hooded region” with an extended, blunt tip. The optical fiber fits within the endoscope has a side or end firing tip with an emission surface. A guide element is adapted to movably support the optical fiber in a position spaced away from the working region, and limit lateral movement of the tip without preventing longitudinal and rotational movement. An irrigant flow arrangement operates to direct inflowing irrigant over the emission surface of the tip. The fiber is assembled with a fiber coupler, a handle, a fiber port cap, and a travel limiter fixed to the fiber at a predetermined distance from the tip. The travel limiter cooperates with the endoscope and the fiber port cap to limit longitudinal and rotational movement of the fiber.

Abstract: A steerable laser probe may include a handle, and inner bore of the handle, an actuation structure of the handle, a housing tube, and an optic fiber disposed within the inner bore of the handle and the housing tube. The housing tube may include a first housing tube portion having a first stiffness and a second housing tube portion having a second stiffness. The second stiffness may be greater than the first stiffness. A surgeon may aim the steerable laser probe by varying a rotational position of the handle and an amount of compression of the actuation structure.

Abstract: A method for removing tattoos using two laser beams and a multi-photon process is disclosed. A 0.1 to 100 nsec pulse secondary laser beam focused to 108 W/cm2 creates a temporary channel from the skin surface to the tattoo pigment. A 100 fsec pulse main laser beam is then guided through the channel to the pigment and focused to sufficient intensity, i.e., 1012 W/cm2 or more, to initiate a multi-photon process that breaks up the pigment, disrupting its light reflecting properties. The channel allows the main laser beam unobstructed passage to the pigments, resulting in efficient use of the main laser. The pigment fragments escape through the temporary channel or diffuse into the blood stream. A suitably configured Ti/Sapphire laser beam is split into two components, with an uncompressed component used as the secondary laser beam, and a compressed component as the main laser beam.

Abstract: A steerable laser probe may include an actuation structure, a nosecone fixed to the actuation structure by one or more links and one or more link pins, a housing tube having a first housing tube portion with a first stiffness and a second housing tube portion with a second stiffness, and an optic fiber disposed in the housing tube and the actuation structure. A compression of the actuation structure may be configured to gradually curve the housing tube and the optic fiber. A decompression of the actuation structure may be configured to gradually straighten the housing tube and the optic fiber.

Abstract: In one embodiment, an apparatus may include an optical fiber that may have a surface non-normal to a longitudinal axis of a distal end portion of the optical fiber. The surface may define a portion of an interface configured to redirect electromagnetic radiation propagated from within the optical fiber and incident on the interface to a direction offset from the longitudinal axis. The apparatus may also include a doped silica cap that may be fused to the optical fiber such that the surface of the optical fiber may be disposed within a cavity defined by the doped silica cap.

Abstract: The disclosure describes an elongated housing, e.g., a catheter, configured to be inserted into a lumen of a patient to diagnose or treat a patient. The elongated housing includes a scope channel that accepts a cystoscope and a viewing window at the distal end of the elongated housing. The user may use the cystoscope to view tissue adjacent to the viewing window. The viewing window may take up at least 10 percent of the length of the elongated housing to allow the user to identify a large area of tissue in the lumen without moving the elongated housing with respect to the tissue. Once the user identifies the target tissue, the user may position the elongated housing graduations on the viewing window and the proximal end of the elongated housing. An ablation needle electrode may be extended into the target tissue to deliver ablation therapy to the target tissue.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may be a deflectable medical device that includes a catheter shaft having a distal end. An ablation electrode may be disposed at the distal end. A deflection mechanism may be coupled to the catheter shaft. The deflection mechanism may include a deflection body and a pull wire coupled to the deflection body. The deflection body may have a longitudinally-extending furrow formed therein. A flex member may be disposed adjacent to the deflection mechanism.

Abstract: A light-based method of endovascular treatment, in particular, of pathologically altered blood vessels. Provided are a Method of Endovascular Light Treatment and a corresponding Endovascular Light Application Device.

Abstract: Deep Tissue Low Intensity Laser Therapy or Treatment (DT-LILT) as described here is a novel methodology through which selective destruction of nociceptive (pain) nerves can be brought upon by a medical laser delivery system using the phenomenon of absorption and cell resonance. Using this method nerve cells that transmit pain can be selectively destroyed leaving the surrounding tissues intact as no heat is generated. The delivery system incorporates a fine needle through which a 703 nm (range 690 to 710) pulsed wave low intensity laser is delivered deep into the body, directly to the area of pain causing selective destruction of pain nerves. Laser devices based on this methodology should be used only by the physician or equivalent professional community since diagnosing and defining the area of pain is critical to providing successful pain relief.

Abstract: A catheter is adapted to ablate tissue and provide lesion qualitative information on a real time basis, having an ablation tip section with a generally omni-directional light diffusion chamber with one openings to allow light energy in the chamber to radiate the tissue and return to the chamber. The chamber is irrigated at a positive pressure differential to continuously flush the opening with fluid. The light energy returning to the chamber from the tissue conveys a tissue parameter, including without limitation, lesion formation, depth of penetration of lesion, cross-sectional area of lesion, formation of char during ablation, recognition of char during ablation, recognition of char from non-charred tissue, formation of coagulum around the ablation site, differentiation of coagulated from non-coagulated blood, differentiation of ablated from healthy tissue, tissue proximity, and recognition of steam formation in the tissue for prevention of steam pop.