Abstract: Insertion of a spinal stabilization element into a patient generally includes positioning a cord within a sheath and inserting the sheath and cord through the patient's body along a path generally toward an anchor member. An advancement member may be mounted on the leading end of the cord to further facilitate this insertion. The sheath is then retracted to expose a first portion of the cord within the patient's body, and the first portion of the cord is moved into a desired position relative to the anchor member. After advancing a spacer over the sheath and cord, the sheath is retracted to expose a second portion of the cord. The second portion of the cord is then moved into a desired position relative to another anchor member such that the spacer is positioned between the two anchor members.

Abstract: A spinal alignment system for interconnecting vertebral bodies is disclosed. The system includes a bone screw polyaxially connected to a seat. The seat includes a top opening, a first rod receiving portion and a second rod receiving portion, a first rod channel and a second rod channel. The system is implanted into a first vertebral body. A first rod is introduced to the seat through the top opening in a first orientation and connected to the first rod receiving portion. A second rod is introduced to the seat through the top opening in a first orientation and connected to the second rod receiving portion. The first and second rods are each moved into a second orientation such that the rods project through the first and second rod channels, respectively. The rods are capable of polyaxial movement with respect to the seat for landing the opposite ends of the rods in adjacent seats of screw systems implanted in other vertebral bodies.

Abstract: A system and methods for performing spinal fixation, including a spinal fixation system with at least rod member having shaped ends, at least two pedicle screws capable of receiving the shaped ends of the rod member, and a system for percutaneously introducing the rod member and pedicle screws to perform spinal fixation.

Abstract: A dynamic spinal stabilization assembly includes a rod having a plurality of slidable collars thereon. The rod is mounted to at least one of the relevant bone anchoring element(s) via the collars. The collars are spaced from one another such that the bone anchoring element engages at least two collars. The collars may be arranged on the rod so that adjacent collars are longitudinally spaced from one another by a distance not more than one-half the length of the rod-receiving channel in the relevant bone anchoring element. There may be elastic elements slidably disposed on the rod between adjacent collars.

Abstract: A bone screw and method of inserting a bone screw into a bone is disclosed. In one example, the bone screw includes a tip segment for creating a starter hole in the bone. A pilot segment is located proximally of the tip segment for creating a pilot hole in the bone after creation of the starter hole. A threaded segment is located proximally of the pilot segment for fixedly securing the bone screw in the bone. A head is located proximally of the threaded segment for allowing a surgical rod to be fixedly secured to the bone screw.

Abstract: A fixation system is designed to lock an elongated member within a housing member, permitting positional and/or orientational adjustment of the elongated member prior to locking. The system includes a housing member, a slotted spherical collet, an elongated member, and may include a tapered wedge, which may be a discrete component or formed as part of the elongated member. The housing member and/or elongated member may be implantable. The elongated member may be positioned in the wedge, the wedge in the collet, and the collet in the housing such that when compression force is applied to the wedge and the collet, the wedge contracts about the elongated member and the collet expands to engage the housing, thus locking the elongated member relative to the housing. The collet may have a tapered channel with a degree of taper equal to the tapered wedge. The collet may have multiple slots to allow uniform radial expansion and compression.

Abstract: A spine stabilization system having a dynamic screw comprises at least one bone anchor assembly comprising a receiver member and a bone engaging member. In one embodiment, the bone engaging member is a screw shank extending from the receiver member. A rod is connected to the receiver member. In one embodiment, the rod comprises a ball-shaped member that engages a bearing surface provided within a cavity of the receiver member. In this embodiment, the rod is pivotably connected to the receiver member. In one such embodiment, a central axis defined by the rod pivots about a pivot point located on the central axis when the rod pivots relative to the receiver member. Accordingly, the pivot point for the rod may be provided within the cavity of the receiver member. The rod may be a fixed length or adjustable to accommodate different segmental units and patients of different sizes.

Abstract: Methods and devices are provided for spinal fixation. In one exemplary embodiment, the methods and devices provide one or more points of fixation located adjacent to a first fixation point at which a bone anchor is implanted in bone. For example, an extension member can be coupled, either directly or indirectly, to a bone anchor, and a fastener can be used to anchor the extension member to bone at a second point of fixation adjacent to the first point of fixation. The second point of fixation can be effective to prevent rotation or other movement of the bone anchor, thereby stabilizing the bone anchor. The methods and devices are particularly useful for unilateral fixation, in which one or more levels of the spine are stabilized along a single lateral side of the spine.

Abstract: A spinal implant system comprises at least two fixation elements, each including a threaded bone-engaging portion, and at least two corresponding receiver members, each including two branches defining a U-shaped channel configured to receive an elongated member. The receiver members are positionable in both open and closed positions. The system further comprises at least one elongated member configured to be positioned in the channels. Additionally, the system comprises at least two snap-fit caps configured to snap on to the receiver members near the top surfaces of the corresponding branches to substantially lock the receiver members in closed positions and capture the elongated member in the channels.

Abstract: A medical device includes a handle, a sheath, and an object-engaging unit. The distal end portion of the sheath is strong enough to resist being deformed by the object-engaging unit, yet another portion of the sheath is flexible enough to bend sufficiently.

Abstract: A method for fixation of biological tissues, and bioprosthetic devices prepared by such method. The method generally comprises the steps of A) fixing the tissue, B) treating the tissue with a mixture of i) a denaturant, ii) a surfactant and iii) a crosslinking agent, C) fabricating or forming the bioprosthesis (e.g., forming the tissue and attaching any non-biological components thereto) and D) subjecting the bioprosthesis to terminal sterilization.