Stimulating Reproductive Organ Patents (Class 607/39)
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Patent number: 8825163Abstract: Systems and methods selectively stimulate components of the pudendal nerve away from the sacral root to evoke desired physiologic responses in persons who lack the ability to otherwise produce these responses—e.g., maintain continence and/or produce micturition, and/or provide male/female sexuality responses, and/or provide bowel responses. The systems and methods use a multiple electrode array, or individual electrodes, placed on, in, or near the pudendal nerve. The electrode array, or individual electrodes, in association with a pulse generator, provide selective stimulation of individual fascicles within the pudendal nerve, to achieve different physiologic responses.Type: GrantFiled: October 15, 2009Date of Patent: September 2, 2014Assignee: Case Western Reserve UniversityInventors: Warren M. Grill, Kenneth J. Gustafson, Graham H. Creasey
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Patent number: 8818520Abstract: A tibial nerve stimulation device including a percutaneous electrode for inserting adjacent a stimulation site of a patient and a neurostimulator unit attachable to a transcutaneous electrode configured to be applied to skin adjacent the stimulation site. The neurostimulator unit includes a pulse generator electrically coupled to the percutaneous needle electrode and transcutaneous electrode and a microcontroller in communication with the pulse generator for monitoring a number of available treatment credits and activating the pulse generator, each available treatment credit corresponding to a treatment session and the pulse generator operable to be activated for performing the treatment session when the number of available treatment credits is at least one. A computer system is operable to communicate with the microcontroller of the neurostimulator unit for receiving a treatment credit request and transmitting the number of treatment credits purchased to the microcontroller of the neurostimulator unit.Type: GrantFiled: January 7, 2014Date of Patent: August 26, 2014Assignee: Advanced Uro-Solutions, LLCInventors: Brent Laing, John David Green
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Patent number: 8805507Abstract: A method of promoting the healing of a lesion in a smooth muscle (200), comprises selecting a smooth muscle portion having a lesion, and applying a non-excitory electric field (210) to the portion, which reduces the mechanical activity of the portion.Type: GrantFiled: October 31, 2007Date of Patent: August 12, 2014Assignee: Metacure LimitedInventors: Shlomo Ben-Haim, Nissim Darvish, Yuval Mika, Maier Fenster, Bella Felzen, Isaac Shemer
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Publication number: 20140214112Abstract: An implantable electroacupuncture device (IEAD) treats an erectile dysfunction condition of a patient through application of stimulation pulses applied at a target tissue location underlying, or in the vicinity of, at least one of acupoints BL52, BL23 or GV4. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.Type: ApplicationFiled: March 4, 2013Publication date: July 31, 2014Applicant: VALENCIA TECHNOLOGIES CORPORATIONInventor: Valencia Technologies Corporation
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Publication number: 20140214113Abstract: An implantable electroacupuncture device (IEAD) treats a medical condition of a patient through application of electroacupuncture (EA) stimulation pulses applied at a target tissue location, such as an acupoint. The IEAD comprises an implantable, coin-sized, self-contained, leadless electroacupuncture device having at least two electrodes attached to an outside surface of its housing. The device generates EA stimulation pulses in accordance with a specified stimulation regimen. Power management circuitry within the device allows a primary battery, having a high internal impedance, to be used to power the device. The stimulation regimen generates stimulation pulses during a stimulation session of duration T3 minutes applied every T4 minutes. The duty cycle, or ratio T3/T4, is very low, no greater than 0.05. The low duty cycle and careful power management allow the IEAD to perform its intended function for several years.Type: ApplicationFiled: March 12, 2013Publication date: July 31, 2014Applicant: VALENCIA TECHNOLOGIES CORPORATIONInventors: Jeffrey H. Greiner, David K. L. Peterson, Chuladatta Thenuwara, Stacy O. Greiner
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Patent number: 8784345Abstract: A stimulation device for creating a pleasurable sensation in a user is provided. The stimulation device includes an expandable portion configured to assume a plurality of states of expansion between minimum expansion and maximum expansion and a vibrating element extending away from the outer surface of the expandable portion.Type: GrantFiled: April 27, 2012Date of Patent: July 22, 2014Assignee: Incontrol Medical, LLCInventor: Herschel Peddicord
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Patent number: 8788040Abstract: A device for stimulating nerves adjacent the vagina includes a nerve stimulating element coupled to a body. The nerve stimulating element is positioned to stimulate the vesical, Frankenhauser's and/or inferior hypogastric plexuses. The device may reside in the vaginal fornices.Type: GrantFiled: June 9, 2012Date of Patent: July 22, 2014Assignee: FemPulse, LLCInventor: Alexandra Haessler
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Publication number: 20140148870Abstract: In certain variations, systems and/or methods for electromagnetic induction therapy are provided. One or more ergonomic or body contoured applicators may be included. The applicators include one or more conductive coils configured to generate an electromagnetic or magnetic field focused on a target nerve, muscle or other body tissues positioned in proximity to the coil. One or more sensors may be utilized to detect stimulation and to provide feedback about the efficacy of the applied electromagnetic induction therapy. A controller may be adjustable to vary a current through a coil to adjust the magnetic field focused upon the target nerve, muscle or other body tissues based on the feedback provide by a sensor or by a patient. In certain systems or methods, pulsed magnetic fields may be intermittently applied to a target nerve, muscle or tissue without causing habituation.Type: ApplicationFiled: November 20, 2013Publication date: May 29, 2014Applicant: EMKINETICS, INC.Inventor: Daniel R. BURNETT
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Patent number: 8702685Abstract: Drug delivery systems, apparatus and methods to treat erectile dysfunction via an implanted drug infusion pump. The drug delivery system incorporates a passively pressurized drug infusion pump, one or more catheters, one or more microfluidic valves, a microcontroller, and one or more patient input mechanisms to deliver therapeutic solutions to the erectile tissues of a patient. The system in operation is entirely implanted and provides for moderated patient control over dosage via subcutaneously implanted input mechanisms, including in certain embodiments, neural control.Type: GrantFiled: November 15, 2010Date of Patent: April 22, 2014Inventors: Matthew Zane Schwartz, Robert Matthew Douglas
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Patent number: 8675945Abstract: A system and method for providing processable data associated with anatomical images may provide a user interface including a pivot and stem tool via which to align multiple images, a flashlight bar for viewing portions of an overlaid image, and/or user-movable markers for establishing a location of one or more anatomical landmarks with regions of one or more images.Type: GrantFiled: March 27, 2012Date of Patent: March 18, 2014Assignee: Boston Scientific Neuromodulation CorporationInventors: Jordan Barnhorst, Keith Carlton, Scott Kokones, Troy Sparks, Aaron Omar Shinn, Zhen Zeng
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Publication number: 20140058473Abstract: Some embodiments of the invention provide a system and method for treating insufficient uterine contractions after labor and delivery. The system includes a control module and a current source controlled by the control module to produce stimulating current at a frequency greater than or equal to about 5.0 Hertz. The system also includes one or more stimulation electrodes to provide the stimulating current to the patient in order for the patient to produce tonic uterine contractions.Type: ApplicationFiled: November 5, 2013Publication date: February 27, 2014Inventors: Robert E. Garfield, Harvey Carp, William L. Maner
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Patent number: 8660646Abstract: A tibial nerve stimulation device including a percutaneous electrode for inserting adjacent a stimulation site of a patient and a neurostimulator unit attachable to a transcutaneous electrode configured to be applied to skin adjacent the stimulation site. The neurostimulator unit includes a pulse generator electrically coupled to the percutaneous needle electrode and transcutaneous electrode and a microcontroller in communication with the pulse generator for monitoring a number of available treatment credits and activating the pulse generator, each available treatment credit corresponding to a treatment session and the pulse generator operable to be activated for performing the treatment session when the number of available treatment credits is at least one. A computer system is operable to communicate with the microcontroller of the neurostimulator unit for receiving a treatment credit request and transmitting the number of treatment credits purchased to the microcontroller of the neurostimulator unit.Type: GrantFiled: June 15, 2012Date of Patent: February 25, 2014Assignee: Advanced Uro-Solutions, LLCInventors: Brent Laing, John David Green
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Patent number: 8630711Abstract: Methods and related systems for treating patients suffering from several disorders including bladder dysfunction, erectile dysfunction, and bowel elimination disorders are disclosed and described. The method can include identification of the disorder followed by the step of accessing a pudendal nerve of the patient. A microelectrode array having a plurality of electrodes thereon is inserted into the pudendal nerve of the patient. A controller is electronically associated with the microelectrode array which is programmed to provide selective activation and/or blocking of various muscles using the microelectrodes of the array. The selective stimulation can be tuned to selectively activate or block at least one muscle selected from the group consisting of the external urethral sphincter, the detrusor muscle, the anal sphincter, and the cavernous smooth musculature of the penis.Type: GrantFiled: October 2, 2009Date of Patent: January 14, 2014Assignee: University of Utah Research FoundationInventors: Heather A. C. Wark, Patrick C. Cartwright, Richard A. Normann
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Patent number: 8606371Abstract: Some embodiments of the invention provide a system and method for treating insufficient uterine contractions after labor and delivery. The system includes a control module and a current source controlled by the control module to produce stimulating current at a frequency greater than or equal to about 5.0 Hertz. The system also includes one or more stimulation electrodes to provide the stimulating current to the patient in order for the patient to produce tonic uterine contractions.Type: GrantFiled: April 7, 2010Date of Patent: December 10, 2013Assignee: Dignity HealthInventors: Robert E. Garfield, Harvey Carp, William L. Maner
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Patent number: 8600510Abstract: There is disclosed an apparatus for treating a sexual dysfunctional female patient, comprising an implanted stimulation device adapted to stimulate at least a part of the sexually responsive tissue of the vulva or the wall of the vagina of the patient by movement of said stimulation device and contact between said stimulation device and the sexually responsive tissue or the wall of the vagina. A system and an operation method for the treatment of female sexual dysfunction are also disclosed.Type: GrantFiled: October 9, 2009Date of Patent: December 3, 2013Assignee: Milux Holding SAInventor: Peter Forsell
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Publication number: 20130296963Abstract: A device, system and method for improving sexual erectile functions in males that includes an electromyography (EMG) sensor, which is set up in the perineum area over the bulbospongiosus and ischiocavernosus muscles. A cable connects the EMG sensor to an amplifier, the output of which is connected to an analog-to-digital converter. The converter transforms the EMG signal into a form that is accepted by a computer or a smartphone, which contains software that is able to display the EMG signal in a visual-auditory form that can be accepted by the sensory organs of a user. The training of the perineum muscles restricts the blood outflow from the cavernous bodies of a penis and reinforcement of erectile function.Type: ApplicationFiled: June 28, 2013Publication date: November 7, 2013Inventors: Eugene Mikhailenok, Olga Voronina
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Patent number: 8573228Abstract: A system includes (i) a needle for insertion into a port of an implantable infusion device, and (ii) a receiver apparatus having a port location signal receiver module capable of receiving a signal from the implantable infusion device regarding spatial orientation of the port. The system further includes a processor operably coupled to the receiver apparatus and capable of determining the orientation of the needle relative to the port based on the received signal. The system also includes a display operably coupled to the processor. The processor is configured to cause the display to graphically render trajectory of the needle relative to the port. The port is graphically rendered as a target structure having a reference area. The needle is graphically rendered as an object moveable relative to the target structure. Occupation of the reference area by the object indicates trajectory alignment of the port and the needle.Type: GrantFiled: September 9, 2008Date of Patent: November 5, 2013Assignee: Medtronic, Inc.Inventor: Scott L. Kalpin
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Publication number: 20130253299Abstract: Methods and apparatuses for monitoring and regulating physiological states and functions are disclosed. Several embodiments include application of one or more microelectrode arrays to a dorsal root ganglion for measurement of sensory neuron activity, or stimulation of sensory reflex circuits. The methods and apparatuses can be used, for example, for monitoring or controlling bladder function in a patient.Type: ApplicationFiled: March 15, 2013Publication date: September 26, 2013Applicant: University of Pittsburgh - Of the Commonwealth System of Higher EducationInventor: University of Pittsburgh - Of the Commonwealth System of Higher Education
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Publication number: 20130237750Abstract: A sexual stimulation device is described. The device uses electrical stimulation and provides advantages in means to make gentle and safe electrical contact to the user's penis that is contained within a fluid environment. The device includes both a containment vessel as well as electrical connection embodiments that incorporate magnetically actuated contacts the can be quickly disconnected. The device provides flexibility for programmed and varied stimulation to different regions of the user's penis.Type: ApplicationFiled: March 5, 2013Publication date: September 12, 2013Inventor: Robert M. Green
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Patent number: 8494626Abstract: Neurostimulators and methods of using neurostimulators are provided. The neurostimulator is implanted within a tissue pocket of a patient, and electrical energy is conveyed from the neurostimulator to stimulate a target tissue site remote from the tissue pocket. The neurostimulator has a case with which one or more electrodes are associated. The electrical energy is returned to the electrode(s) in a manner that prevents, or at least reduces, pocket stimulation that may otherwise occur due to the return of electrical energy to the case of the neurostimulator.Type: GrantFiled: December 3, 2009Date of Patent: July 23, 2013Assignee: Boston Scientific Neuromodulation CorporationInventors: Michael A. Moffitt, Dongchul Lee
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Patent number: 8478410Abstract: A procedure electrically stimulates a nerve or group of nerves. Unlike conventional systems this procedure is tuned to target a large or small group of neurons using noninvasive electromagnetic induction. This system is capable of doing this by using the principles of the alternating current in a capacitance inductance series resonance circuit. In this system the nerve resonator treats the neuron like a thin conductor placed between the plates of a capacitor in series with an inductor and then tuned to resonate with the appropriate frequency of alternating current. The system could also be inductance tuned for a given frequency. Once the system is tuned, the current amplitude in the entire circuit including the thin conductor or nerve fiber can be externally controlled.Type: GrantFiled: September 8, 2009Date of Patent: July 2, 2013Inventor: Michael F. Kivlighan
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Publication number: 20130144357Abstract: Described herein is a device and method for stimulating testosterone production in a subject. The device includes a first electrode, a second electrode, and a power source. The first electrode is configured to contact the skin in the pubic region of the subject and is electrically coupled to the power source. The second electrode is configured to contact the skin on the scrotum of the subject and is also electrically coupled to the power source. The power source is configured to deliver about 6 volts or less to the first or second electrodes. The device may further include a snug fitting undergarment for maintaining contact between the first and second electrodes and the subject's skin. The method is directed to the application of a low voltage to the testicles of a subject to stimulate the production of testosterone.Type: ApplicationFiled: December 5, 2011Publication date: June 6, 2013Inventor: Robert D. Forward
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Publication number: 20130116742Abstract: A measuring method enables the strength of the ischiocavernosus muscles (IC) causing the rigidity of the penis (P) of a patient and the arterial and venous variation ensuring the erection of the penis (P) of the patient to be measured and reinforced by placing a sensor (2, 50) around the penis (P) includes elements to receive the intracavernous pressure (ICP) and pressure variations of the penis (P), and at least one transducer (21, 55) integrated into or offset from the sensor (2, 50) allowing the pressure signal from the elements for receiving the pressure to be transformed into an electrical signal, and by connecting the sensor (2, 50) to a housing (35) including elements for amplifying and recording the signal from the transducer (21, 55), elements for analyzing the signal by a microcontroller allowing the fatigue state of the ischiocavernosus muscles (IC) to be measured and the variations in muscle strength of the ischiocavernosus muscles (IC) to be measured.Type: ApplicationFiled: December 27, 2012Publication date: May 9, 2013Inventor: Pierre LAVOISIER
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Publication number: 20130096640Abstract: A method for treating an impaired body function in a patient, including the steps of (a) laparoscopically implanting at least one neuroprothesis electrode on a least one endopelvic nerve root of a patient; (b) electrostimulating the nerve root with the electrode for a predetermined time period to induce a body function of the patient; and (c) during the predetermined time period, instructing the patient to mentally concentrate on performing the body function.Type: ApplicationFiled: October 12, 2012Publication date: April 18, 2013Inventor: Marc Possover
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Patent number: 8423146Abstract: The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.Type: GrantFiled: August 23, 2010Date of Patent: April 16, 2013Assignee: Medtronic, Inc.Inventors: Jonathon E. Giftakis, Martin T. Gerber
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Publication number: 20130023949Abstract: A method for altering operation of a nerve related to a given body condition includes the steps of identifying at least one nerve root of a nerve related to the given body condition; laparoscopically implanting at least one electrode on the nerve root; and operating the electrode to electrostimulate the nerve root and alter operation of the nerve.Type: ApplicationFiled: September 17, 2012Publication date: January 24, 2013Inventor: Marc Possover
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Publication number: 20130006322Abstract: Provided herein are methods and devices useful for inhibiting or treating urological conditions, such as overactive bladder (OAB) symptoms including bladder overactivity, urinary frequency, urinary urgency, urinary incontinence, interstitial cystitis (IC), urinary retention, and pelvic pain; gastrointestinal conditions, such as fecal incontinence, irritable bowel syndrome (IBS), and constipation; and sexual conditions, such as premature ejaculation, erectile disorder, and female sexual arousal disorder by non-invasive transcutaneous electrical stimulation of the foot.Type: ApplicationFiled: September 30, 2010Publication date: January 3, 2013Applicant: UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEInventor: Changfeng Tai
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Patent number: 8290594Abstract: A male sexual impotence treatment apparatus includes or use an operable restriction device implantable in a male patient for engaging a tissue portion of the penile tissue to form a restrictable passageway for the penile exit blood flow. An energy transmission device is provided for wireless transmission of energy from outside the patient's body to inside the patient's body for use in connection with the operation of the restriction device, including temporarily contracting said tissue portion to restrict the penile exit blood flow in the blood flow passageway to achieve erection.Type: GrantFiled: August 19, 2010Date of Patent: October 16, 2012Assignee: Obtech Medical AGInventor: Peter Forsell
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Patent number: 8233990Abstract: A selection of parameter configurations for a neurostimulator using decision trees may be employed by a programming device to allow a clinician or other user to select parameter configurations, and then program an implantable neurostimulator to deliver therapy using the selected parameter configurations. The programming device executes a parameter configuration search algorithm to guide the clinician in selection of parameter configurations. The search algorithm relies on a decision tree to identify optimum parameter configurations. A decision tree is useful in classifying observations in a data set based upon one or more attributes or fields within the data. The data set includes parameter configurations matched with observed ratings of efficacy on patients of a similar indication. The learned attribute, on which classification occurs, will be the optimum parameter configuration for a set of rated configurations used to produce the classification.Type: GrantFiled: September 14, 2009Date of Patent: July 31, 2012Assignee: Medtronic, Inc.Inventor: Steven M. Goetz
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Publication number: 20120191156Abstract: A method of treating a wide variety of heretofore considered unrelated ailments comprises delivering electricity through a circuit in the body. The circuit includes at least four nerves leading from at least two of the patient's extremities to various nerve roots adjacent the spinal column. Electrical energy from an electrical interferential therapy device is delivered through electrodes on the extremities adjacent the nerve endings until symptoms of the diagnosed ailment ameliorates. Sending impulses from the periphery to the central nervous system appears to the help the body manufacture various neuropeptides and other chemicals which control the essential basics of the body's health and well being.Type: ApplicationFiled: March 27, 2012Publication date: July 26, 2012Inventor: Donald A. Rhodes
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Patent number: 8204569Abstract: The invention includes an implantable medical electrical lead for electrical stimulation of body tissue that includes at least one electrode; a lead body; and at least one modifiable portion that is coaxial with the lead body, wherein the at least one modifiable portion can exist in both a first configuration and a second configuration, wherein the second configuration exhibits a greater resistance to movement of the lead within the body tissue than does the first configuration, and wherein the first configuration is exhibited when an external force is applied to the outer surface of the modifiable portion. Kits, systems and methods of implanting are also included in the invention.Type: GrantFiled: April 27, 2006Date of Patent: June 19, 2012Assignee: Medtronic, Inc.Inventors: Martin T. Gerber, Eric H. Bonde
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Patent number: 8126558Abstract: A male sexual impotence prosthesis apparatus comprises an operable prosthesis implanted in the cavities of the corpora cavemosa of a patient's penile tissue for providing erect penile condition, when the prosthesis is operated. The prosthesis is operable by an implanted operation device. A control device is provided for controlling a source of energy, which may or may not be implanted, from outside the patient's body, to release energy for use in connection with the operation of the prosthesis, i.e., to power the operation device. The patient uses the control device to operate the prosthesis to achieve erection.Type: GrantFiled: May 22, 2006Date of Patent: February 28, 2012Assignee: Obtech Medical AGInventor: Peter Forsell
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Patent number: 8121690Abstract: Methods are provided for treating a subject for a fertility condition. In accordance with the subject methods, at least a portion of a subject's autonomic nervous system is modulated to increase the sympathetic activity/parasympathetic activity ratio in a manner that is effective to treat the subject for the condition. Embodiments of the subject invention include modulating a subject's autonomic nervous system using electrical energy and/or one or more pharmacological agents. The subject methods find use in the treatment of a variety of different fertility conditions. Also provided are kits for use in practicing the subject methods.Type: GrantFiled: January 22, 2010Date of Patent: February 21, 2012Assignee: Palo Alto InvestorsInventors: Anthony Joonkyoo Yun, Patrick Yuarn-Bor Lee
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Publication number: 20110230930Abstract: There is disclosed an apparatus for treating a sexual dysfunctional female patient, comprising a stimulation device adapted to stimulate an erectile blood flow passageway to increase the amount of blood in the female erectile tissue and thereby obtaining engorgement with blood of the female erectile tissue by affecting said erectile blood flow passageway. Moreover there is disclosed a system and an operation method for treating a sexual dysfunctional female patient.Type: ApplicationFiled: October 9, 2009Publication date: September 22, 2011Applicant: MILUX HOLDING SAInventor: Peter Forsell
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Publication number: 20110230857Abstract: In accordance with some embodiments of the present invention, delivery systems and methods for delivering a substance in a medium is provided. The delivery system may include a delivery component, an electronic controller, one or more sensors, and a feedback mechanism. The delivery component has at least one reservoir that contains a substance (e.g., a liquid, a drug, etc.). The electronic controller is connected to the delivery component and controls the release of the substance from the at least one reservoir into the medium. The sensors monitor one or more parameters in the medium and provide a signal to a feedback mechanism. The feedback mechanism, in response to the signal, sends an electrical signal that directs the controller to release the substance from the reservoir into the medium, thereby maintaining a desire level of a monitored parameter (e.g., pH, pO2, temperature, pressure, ions, volume, impedance, dosage, biomarkers, etc.).Type: ApplicationFiled: April 4, 2008Publication date: September 22, 2011Inventor: Ewa Herbst
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Publication number: 20110144468Abstract: Systems and methods use an external and/or implantable pulse generator system for neuromodulation stimulation to treat sexual dysfunction by the unilateral or bilateral stimulation of a target nerve A and/or a target nerve B using one or more leads and electrodes implanted in tissue in the pelvic region. The electrical stimulation waveform may be conveyed to the target nerve A electrode for a first predetermined amount of time, and conveyed to the target nerve B electrode for a second predetermined amount of time.Type: ApplicationFiled: February 21, 2011Publication date: June 16, 2011Applicant: MEDTRONIC URINARY SOLUTIONS, INC.Inventors: Joseph W. Boggs, Robert B. Strother, Joseph J. Mrva, Geoffrey B. Thrope
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Patent number: 7957805Abstract: An implantable microstimulator includes a housing, an electronic subassembly, conductive vias, and an electrode arrangement. The housing defines an interior and an exterior with the electronic subassembly disposed in the interior of the housing. The conductive vias extend from the interior to the exterior of the housing. The electrode arrangement is disposed on the housing and includes a film substrate with electrodes disposed on the film substrate and coupled to the electronic subassembly through the plurality of vias.Type: GrantFiled: June 1, 2005Date of Patent: June 7, 2011Assignee: Boston Scientific Neuromodulation CorporationInventor: Tom Xiaohai He
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Publication number: 20110087337Abstract: An apparatus for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ comprises an implantable constriction device for gently constricting (i.e. without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and a stimulation device for stimulating the wall portion of the tissue wall. A control device controls the stimulation device to stimulate the wall portion, as the constriction device constricts the wall portion, to cause contraction of the wall portion constricted by the constriction device to further influence the flow in the lumen. The apparatus can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ.Type: ApplicationFiled: April 12, 2010Publication date: April 14, 2011Inventor: Peter FORSELL
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Publication number: 20110066254Abstract: There is provided a method for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the lumen. The method can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ. Such an organ may be the esophagus, stomach, intestines, urine bladder, urethra, ureter, renal pelvis, aorta, corpus cavernosum, exit veins of erectile tissue, uterine tube, vas deferens or bile duct, or a blood vessel.Type: ApplicationFiled: April 12, 2010Publication date: March 17, 2011Inventor: Peter FORSELL
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Patent number: 7899539Abstract: Methods of using unidirectionally propagating action potentials (UPAPs) for cavernous nerve stimulation and for certain disorders are provided. Stimulators capable of creating such UPAPs include, but are not limited to, miniature implantable stimulators (i.e., microstimulators), possibly with programmably configurable electrodes. A method of stimulating a cavernous nerve includes providing at least one implantable stimulator with at least two cathodic electrodes; programming stimulation parameters for the cathodic electrodes to radially steer an electric field generated by the cathodic electrodes to apply stimulation that unidirectionally propagates action potentials along a cavernous nerve; and applying the stimulation to the cavernous nerve in accordance with the stimulation parameters to generate orthodromic action potentials traveling in one direction along the nerve, thereby limiting side effects of bidirectional stimulation.Type: GrantFiled: September 28, 2006Date of Patent: March 1, 2011Assignee: Boston Scientific Neuromodulation CorporationInventors: Todd K. Whitehurst, James P. McGivern, Rafael Carbunaru, Matthew I. Haller, Tom Xiaohai He, Kerry Bradley
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Patent number: 7894913Abstract: Systems and methods use an external and/or implantable pulse generator system for neuromodulation stimulation to treat sexual dysfunction by the unilateral or bilateral stimulation of a target nerve A and/or a target nerve B using one or more leads and electrodes implanted in tissue in the pelvic region. The electrical stimulation waveform may be conveyed to the target nerve A electrode for a first predetermined amount of time, and conveyed to the target nerve B electrode for a second predetermined amount of time.Type: GrantFiled: August 9, 2007Date of Patent: February 22, 2011Assignee: Medtronic Urinary Solutions, Inc.Inventors: Joseph W Boggs, Robert B Strother, Joseph J Mrva, Geoffrey B Thrope
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Patent number: 7890177Abstract: An implantable stimulator(s) with at least one infusion outlet and/or at least one electrode, is implanted with the outlet(s) and/or electrode(s) located adjacent to a pudendal nerve(s) and potentially other nerve(s) innervating the reproductive organs, such as the cavernous nerve(s). Stimulation of such nerve(s) is provided via stimulating drugs and/or electrical stimulation as a therapy for erectile dysfunction. The stimulator uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a battery is accomplished, for example, by inductive coupling with an external appliance. The stimulator provides means of stimulating a nerve(s) when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power. The system is capable of open- and closed-loop operation.Type: GrantFiled: January 24, 2006Date of Patent: February 15, 2011Assignee: Boston Scientific Neuromodulation CorporationInventors: Todd K Whitehurst, James P McGivern
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Patent number: 7890176Abstract: Methods of treating chronic pelvic pain include applying at least one stimulus to a stimulation site within a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating chronic pelvic pain include a system control unit configured to apply at least one stimulus to a stimulation site within a patient in accordance with one or more stimulation parameters.Type: GrantFiled: June 17, 2005Date of Patent: February 15, 2011Assignee: Boston Scientific Neuromodulation CorporationInventors: Kristen N. Jaax, Rafael Carbunaru, Todd K. Whitehurst, Carla Mann Woods
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Publication number: 20110015689Abstract: A method of treating a wide variety of heretofore considered unrelated ailments comprises delivering electricity through a circuit in the body. The circuit includes at least four nerves leading from at least two of the patient's extremities to various nerve roots adjacent the spinal column. Electrical energy from an electrical interferential therapy device is delivered through electrodes on the extremities adjacent the nerve endings until symptoms of the diagnosed ailment ameliorates. Sending impulses from the periphery to the central nervous system appears to the help the body manufacture various neuropeptides and other chemicals which control the essential basics of the body's health and well being.Type: ApplicationFiled: September 13, 2010Publication date: January 20, 2011Inventor: Donald A. Rhodes
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Patent number: 7865243Abstract: An implantable stimulator(s) with at least one infusion outlet and/or at least one electrode, is implanted with the outlet(s) and/or electrode(s) located adjacent to a pudendal nerve(s) and potentially other nerve(s) innervating the reproductive organs, such as the cavernous nerve(s). Stimulation of such nerve(s) is provided via stimulating drugs and/or electrical stimulation as a therapy for erectile dysfunction. The stimulator uses a power source/storage device, such as a rechargeable battery. Periodic recharging of such a battery is accomplished, for example, by inductive coupling with an external appliance. The stimulator provides means of stimulating a nerve(s) when desired, without the need for external appliances during the stimulation session. When necessary, external appliances are used for the transmission of data to and/or from the stimulator(s) and for the transmission of power. The system is capable of open- and closed-loop operation.Type: GrantFiled: January 24, 2006Date of Patent: January 4, 2011Assignee: Boston Scientific Neuromodulation CorporationInventors: Todd K Whitehurst, James P McGivern
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Patent number: 7865250Abstract: Systems provide a stimulation electrode assembly sized and configured for placement in an adipose tissue region to stimulate a nerve in the adipose tissue region comprising an elongated lead sized and configured to be implanted within the adipose tissue region, the lead including at least two electrically conductive portions to apply electrical stimulation to nerve tissue in the adipose tissue region, and at least two expandable anchoring structures deployable from the lead to engage adipose tissue and resist dislodgment and/or migration of the at least two electrically conductive portions within the adipose tissue region.Type: GrantFiled: November 30, 2005Date of Patent: January 4, 2011Assignee: Medtronic Urinary Solutions, Inc.Inventors: Joseph J. Mrva, Robert B. Strother, Geoffrey B. Thrope, Julie Grill, Maria E. Bennett
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Publication number: 20100305392Abstract: Apparatus and methods are described including identifying a subject as suffering from a condition selected from the group consisting of congestive heart failure, diastolic heart failure, and hypertension. In response to the identifying, an electrode is placed on a vagus nerve of the subject at a vagal site that is between (a) a vagal bifurcation with a thoracic cardiac branch of the subject, and (b) thoracic vagal branching into the esophageal plexus of the subject. The subject is treated by driving a current into the vagal site, via the electrode. Other embodiments are also described.Type: ApplicationFiled: June 2, 2010Publication date: December 2, 2010Applicant: Enopace Biomedical Ltd.Inventors: Yossi Gross, Amir Dagan, Yotam Reisner, Offer Glasberg, Nitai Hanani, Gal Ariav
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Publication number: 20100286735Abstract: Some embodiments of the invention provide a system and method for treating insufficient uterine contractions after labor and delivery. The system includes a control module and a current source controlled by the control module to produce stimulating current at a frequency greater than or equal to about 5.0 Hertz. The system also includes one or more stimulation electrodes to provide the stimulating current to the patient in order for the patient to produce tonic uterine contractions.Type: ApplicationFiled: April 7, 2010Publication date: November 11, 2010Inventors: Robert E. Garfield, Harvey Carp, William L. Maner
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Patent number: 7818062Abstract: In some embodiments of the present invention, apparatus is provided for treating erectile dysfunction of a subject. The apparatus includes one or more electrodes configured to be coupled to a vicinity of a blood vessel that carries blood into or out of a penis of the subject, and a control unit configured to facilitate erection of the penis by peristaltically pumping blood in the blood vessel by stimulating nitric oxide (NO) production in the vicinity, by driving the electrodes to drive a current into the vicinity. Additional embodiments are also described.Type: GrantFiled: January 31, 2008Date of Patent: October 19, 2010Assignee: Ed Tech Medical Ltd.Inventor: Yossi Gross
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Patent number: 7809443Abstract: The disclosure describes a method and system for applying electrical stimulation to a genitofemoral nerve or a genital branch of a genitofemoral nerve of a patient. The system includes electrical stimulators that apply electrical stimulation for alleviation of pelvic pain. The system may apply electrical stimulation for pelvic pain in men or women. The electrical stimulators may comprise various types of electrodes such as cuff electrodes, electrode leads, and microstimulators implanted at various locations proximate to a single or both genitofemoral nerves and the genital branch of a single or both genitofemoral nerves of a patient. When implanted proximate to a genital nerve branch, the electrode may be implanted proximate to the genital nerve branch. In a male patient stimulation may be delivered proximate to the spermatic cord, which contains a portion of the genital nerve branch.Type: GrantFiled: April 28, 2006Date of Patent: October 5, 2010Assignee: Medtronic, Inc.Inventors: Jonathon E. Giftakis, Martin T. Gerber