Abstract: One aspect of the invention provides a method for preparing a vein graft. The method includes: applying a tissue passivation agent to a resected anatomical vessel; placing the resected anatomical vessel in a chamber; and allowing the tissue passivation agent to cross-link while the resected anatomical vessel is in the chamber.

Abstract: A phototherapy device includes a clothing item. Illuminators are secured to the clothing item and arranged to illuminate at least a portion of a patient wearing the clothing item. The illuminators include light emitting diodes (LEDs) mounted on at least one flexible printed circuit board (PCB). A temperature sensor is secured to the clothing item and positioned to measure a temperature proximate to the patient wearing the clothing item. A control circuit is connected to receive the temperature from the temperature sensor and operative to turn off the illuminators responsive to the temperature exceeding a maximum permitted temperature.

Abstract: Systems and methods for phototherapeutic modulation of nitric oxide in mammalian tissue include use of a first wavelength and first radiant flux of light to stimulate enzymatic generation of nitric oxide, and use of a second wavelength and second radiant flux of light to stimulate release of nitric oxide from endogenous stores of nitric oxide. Pulsed light and/or partially non-overlapping light impingement windows may be used. Non-coherent light impinged on tissue may include a peak wavelength in a range of from 410 nm to 440 nm in the absence of light emissions having a peak wavelength of from 600 nm to 900 nm.

Abstract: Provided is a phototherapeutic apparatus including: a probe that is held and operated by a user and provided with a photo-irradiation unit that performs irradiation with light beams; and a body provided with a control unit that controls the light beams. The body is provided with a read unit that reads a treatment protocol registered in an IC card (mobile memory medium), and a monitor (operation indication unit) that indicates a region to be irradiated with the light beams to the user, the region being set in the treatment protocol, and the control unit causes the monitor to indicate the region to be irradiated and causes the photo-irradiation unit to perform the irradiation with the light beams at a set value set in the treatment protocol. It is possible to perform the irradiation with the light beams in accordance with the treatment protocol and safely use the phototherapeutic apparatus.

Abstract: A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.

Abstract: The present disclosure provides topical biophotonic materials and methods useful in phototherapy. In particular, the topical biophotonic materials of the present disclosure include a cohesive matrix, and at least one chromophore which can absorb and emit light from within the topical biophotonic material, wherein the topical biophotonic material is elastic. The topical bio-photonic materials and the methods of the present disclosure are useful for promoting wound healing and skin rejuvenation, as well as treating acne and various other skin disorders.

Abstract: Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by placing a nanoparticle having a metallic shell on at least a fraction of a surface in a vicinity of a target structure in a subject and applying an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The nanoparticle is configured, upon exposure to a first wavelength ?1, to generate a second wavelength ?2 of radiation having a higher energy than the first wavelength ?1.

Abstract: Disclosed are an apparatus and a system for managing circadian rhythm. The apparatus includes an illuminance measuring portion which measures a bio illuminance value of external light using a circadian lambda filter which passes the external light along according to a circadian rhythm sensitivity curve and a visual lambda filter which passes the external light along according to a visual sensitivity curve, a controller which outputs a control signal for reinforcing a user's circadian rhythm on the basis of the bio illuminance value, and a circadian rhythm reinforcing portion which emits light of a circadian wavelength band toward the user according to the control signal.

Abstract: A light source and a method of generating a light using the light source is disclosed. The light source is configured to produce a plurality of distinct colors in generating the light, one of the distinct colors falling within a blue spectral light band. A light controller modulates the spectral light produced by the plurality of distinct colors. The modulation provides melanopsin contrast in order to increase melanopsin responsiveness of a subject exposed to the generated light and maintains the color temperature, color quality, and color constancy experienced by the subject in a lit viewing environment within an acceptable range.

Abstract: A method and apparatus irradiates a surface with at least one pulsed light beam emitted from an emission surface of an optical element. The at least one pulsed light beam comprises a plurality of pulses having a temporal pulsewidth in a range between about 0.1 millisecond and about 150 seconds. The at least one pulsed light beam has a beam cross-sectional area at the emission surface greater than about 2 cm2 and a time-averaged irradiance in a range between about 1 mW/cm2 and about 100W/cm2.

Abstract: Methods and systems for use in treating one or more patient's sensory impairment, e.g., associated with peripheral neuropathy. An exemplary system may be configured to generate treatment information for treating sensory impairment in at least one body portion using photonic energy from a therapeutic laser based on data indicative of damage.

Abstract: A method and computer program product for suppressing the symptoms of multiple sclerosis (MS) by irradiating a subject exhibiting the symptoms with a pre-determined dose of UV-containing light from a light source and detecting a suppression of the clinical symptoms of MS. In particular, the detected suppression of the clinical symptoms is disassociated from the vitamin D production within the subject.

Abstract: Disclosed are a method and system for controlling a display condition which is pre-written into a passive light board by a mobile device. A display status is pre-written into a passive light board which is not powered by electricity before, and a control application program loaded into the mobile device is provided for a user to input a brightness parameter and a color temperature parameter. The light board which is not powered by electricity before can carry out the presetting of the display condition, and related manufacturers can set the light boards quickly and easily after the light boards exit the factory, and the light boards can display according to the conditions in compliance with the brightness parameter and the color temperature parameter after the light boards are powered on.

Abstract: Optogenetic signal processing is described for an auditory prosthesis with an intracochlear array of optical stimulation sources implanted in a patient having auditory neurons genetically modified with light sensitive ion channels. Stimulation timing signals are generated for the corresponding auditory neurons for each band pass signal based on characteristic temporal fine structure features of the band pass signals. The stimulation timing signals include: i. one or more channel opening signals adapted to open the ion channels of the corresponding auditory neurons, and ii. one or more channel closing signals adapted to close the ion channels of the corresponding ion channels. Optical stimulation signals are then produced for the optical stimulation sources based on the stimulation timing signals.

Abstract: Methods and apparatus provide therapeutic electromagnetic radiation (EMR) for inactivating infectious agents in, on or around a catheter residing in a patient's body cavity and/or for enhancing healthy cell growth. Transmitting non-ultraviolet therapeutic EMR substantially axially along an optical element in a lumen of the catheter body and/or the catheter body. Through delivery of the therapeutic EMR to particular infected areas and/or areas requiring tissue healing. The inactivation of the major sources of infection in, on, and around catheters and/or enhance healthy cell growth around catheters is accomplished by utilizing controlled relative intensity and/or treatment region specific dosing of the therapeutic EMR emitted radially from the optical element. Specific embodiments of urinary catheters and peritoneal dialysis catheters are also disclosed.

Abstract: An illumination system (1) for photodynamic therapy is provided, the illumination system comprising an illumination source (2), which is configured to emit an electromagnetic radiation (3) to illuminate a target surface (4) during operation, and an electronic control unit (5), wherein the illumination source is configured such that the intensity of the electromagnetic radiation emitted by the illumination source can be varied, wherein the electronic control unit is operatively connected to the illumination source and configured to control operation of the illumination source according to an illumination protocol during an illumination session performed with the illumination system, and wherein the illumination protocol comprises instructions to operate the illumination source during the illumination session in a plurality of different modes, the modes comprising: a) a first mode, wherein, in the first mode, the electronic control unit controls operation of the illumination source such that the intensity of th

Abstract: A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.

Abstract: The embodiments herein provide an LED based vaginal light therapy device for a plurality of bacterial and fungal infections. The device comprises an LED body, a cervix support, a single or a plurality of LEDs, a switch, a tether, microchip and a battery. One end of the device comprises a cervix support to place the device smoothly against the cervix. A plurality of LEDs is provided over the LED body. The LED body comprises one or more LEDs and each LED emits a light having a wavelength in a therapeutic zone of light. The light emitted are in a range of blue light and/or red light. The microchip is housed within the LED body. The microchip connects a battery to the single or plurality of LED's and is further connected to the switch.

Abstract: A phototherapy device, a kit containing such a phototherapy device, and a method for treating a patient with a phototherapy device, the phototherapy device containing a housing, an emission portion, and a light tube, the housing containing a light source that emits light at a wavelength of from about 400 nm to about 550 nm, and may contain a light shield proximal to the light source, the emission portion being distal form the housing and connected thereto via a light tube which contains an optical fibre, and a mesh that may enclose the optical fibre and may allow a limited amount of light to leak from the optical fibre to the outside environment.

Abstract: A light health care system including a physiological sensing device, a processor, and a light source device is provided. The physiological sensing device is adapted to acquire physiological data of a user. The processor is coupled to the physiological sensing device, and the processor acquires at least one light parameter corresponding to the physiological data according to the physiological data. The light source device is coupled to the processor, and the light source device outputs a light beam according to the at least one light parameter, wherein a green light beam or a blue light beam in the light beam accounts for more than 40% of the light beam. A light health care method is also provided.

Abstract: A method and apparatus for stimulating neural activity in the brain of a user of an apparatus with a display screen by causing at least one portion of the display screen to flicker in a controlled manner and utilizing the apparatus to measure an effect on a user exposed to the flicker for a time.

Abstract: A system for corneal treatment includes a light source that activates cross-linking in at least one selected region of a cornea treated with a cross-linking agent. The light source delivers photoactivating light to the at least one selected region of the cornea according to a set of parameters. The system includes a controller that receives input relating to the cross-linking agent and the set of parameters. The controller includes computer-readable storage media storing: (A) program instructions for determining cross-linking resulting from reactions involving ROS including at least peroxides, superoxides, and hydroxyl radicals, and (B) program instructions for determining cross-linking from reactions not involving oxygen. The controller executes the program instructions to output a calculated amount of cross-linking in the at least one selected region of the cornea. In response to the calculated amount of cross-linking, the light source adjusts at least one value in the set of parameters.

Abstract: A light emitting device array includes a substrate, a heat sink disposed on the substrate, at least two light emitting devices disposed on the heat sink and spaced apart from each other, a connector disposed on the light emitting device and configured to apply power, an insulating layer interposed between the heat sink and the connector, a fixing member configured to support a position of the light emitting device, on the light emitting device, and an adhesive layer provided on the fixing member to make contact with a skin.

Abstract: A wearable for providing light therapy to a wearer includes at least one fabric panel having an inner surface that when the wearable is worn is configured to face a wearer's skin and an outer surface opposite the inner surface and at least one side-emitting optical fiber affixed to at least one of the inner surface and the outer surface. The side-emitting optical fiber is optically connectable with an optical fiber light source and configured to project light having a therapeutic wavelength toward a wearer of the wearable.

Abstract: There is disclosed an IR illumination device and munitions comprising the same. There is provided an IR illumination munition device for selective activation where upon activation the device emits IR radiation in the range of wavelengths of from 750 nm to 900 nm, the device comprising: an electrical power source; an array of IR light emitting diodes to emit the IR radiation.

Abstract: Phototherapy systems and methods of phototherapy are described. In an example, the phototherapy system includes a therapeutic light source configured to emit phototherapeutic light towards a subject; and a placebo light source configured to emit placebo light towards the subject. In an embodiment, the light, including the phototherapeutic light and the placebo light, emitted by the phototherapy system is configured to be visually perceived by the subject as continuous light. In an embodiment, the placebo light is a metameric match of the phototherapeutic light. In an embodiment, the method includes emitting the placebo light in a wavelength range and at an intensity configured to be visually perceived by the user as the phototherapeutic light, such as where the placebo light is a metameric match of the phototherapeutic light.

Abstract: A wireless optogenetic device in proximity to a neural cell of a subject includes a body configured to hold light transducing materials arranged to up-convert electromagnetic radiation in infrared or near-infrared spectrum into light in the visible spectrum to affect activity of the neural cell. The body allows electromagnetic radiation in infrared or near-infrared to reach the light transducing materials. A radiation system includes a radiation probe for irradiating a wireless optogenetic device with electromagnetic radiation in infrared or near-infrared spectrum from a radiation source. The system further includes a movement mechanism for moving the radiation probe, a detector for detecting a location of the wireless optogenetic device, and a controller for controlling the movement mechanism based on the detected location of the wireless optogenetic device such that the radiation probe is arranged to irradiate the wireless optogenetic device at the detected location with the electromagnetic radiation.

Abstract: An apparatus and methods to form a tissue scaffolding are provided. The apparatus may include a catheter shaft extending from a proximal end to a distal tip, a distal balloon positioned on the catheter shaft proximal to the distal tip, and a proximal balloon positioned on the catheter shaft proximal to the distal balloon. The apparatus may further include an intermediate balloon positioned on a distal segment of the catheter shaft proximal to the distal balloon and distal to the proximal balloon. The intermediate balloon and the distal segment each include a translucent material. A light fiber may extend through the distal segment. A first lumen and a second lumen may be arranged in the catheter shaft, the first lumen comprising a first port located between the distal balloon and the intermediate balloon, and the second lumen comprising a second port located between the intermediate balloon and the proximal balloon.

Abstract: Systems and methods are disclosed for non-invasively measuring blood glucose levels in a biological sample based on spectral data. This includes utilizing at least one light source configured to strike a target area of a sample, utilizing at least one light filter positioned to receive light transmitted through the target area from the at least one light source, utilizing at least one light detector positioned to receive light from the at least one light source and filtered by the at least one light filter, and to generate an output signal, having a time dependent current, which is indicative of the power of light detected, receiving the output signal from the at least one light detector with a processor and based on the received output signal, calculating the attenuance attributable to blood in a sample with a signal-to-noise ratio of at least 20-to-1; and determining a blood glucose level.

Abstract: A removable tip for a light energy handpiece comprises a hollow conduit configured to surround a light guide in the handpiece; a support extension having a length longer than a length of the hollow conduit; and a shielding extension coupled to the support extension at an angle less than 180 degrees and located in front of the hollow conduit. The shielding extension is configured to be inserted behind an eyelid and extend to the fornix, the shielding extension comprised of a thermally insulative material.

Abstract: Embodiments of the present disclosure provide systems, apparatuses and methods for regulation hormone production in mammals. Examples include but are not limited to by creating electro-magnetic wave emission pulse trains (photons) of individual color spectrums in sufficient intensity to drive hormone production in a mammal, using a characteristic frequency or pattern to minimize the required input power necessary to regulate hormone production, while also allowing for the monitoring of the power consumption and other variables of the system. By controlling the duty cycle, intensity, wavelength band and frequency of photon signals to a mammal, production of specific hormones can be regulated through the cycling between blue, green, yellow, near-red, far-red, infrared and ultra violet photon modulation.

Abstract: A method of biostimulating phototherapy is provided. The method comprises illuminating a subject's body portion with light having a first wavelength in the range of 600-900 nm. The method further comprises the step of at least one of reducing and preventing hyperthermia of the body portion by illuminating the body portion with light having a second wavelength which is at least one of in the range of 400-600 nm and in the range of 900-2500 nm. Further, a phototherapy device is provided which comprises a first light source and a second light source. The first light source is configured to emit light having a first wavelength which is in the range of 600-900 nm. The second light source is configured to emit light having a second wavelength which is at least one of in the range of 400-600 nm and in the range of 900-2500 nm. At least a portion of the device is a patch which is formed for conforming to at least part of the body portion.

Abstract: An optrode arrangement for delivering optical stimulation to target tissue in a patient, the optrode arrangement comprising an implantable optrode comprising at least one electrically powered light emitter and an electrical circuit and control lines for controlling the light emitter, whereby an associated controller has two modes of operation: a stimulation mode in which it is configured to control the light emitter to deliver optical stimulation to the target tissue and a diagnostic mode in which it is configured to determine a condition of the light emitter and/or the optrode.

Abstract: Photobiomodulation therapy systems provide a highly effective way to treat many common ailments to the human body. Many embodiments described herein enable two or more light therapy devices to be coupled together in various ways. In some embodiments, the light therapy system includes a first light device and a second light device arranged and configured to be mechanically and/or electrically coupled to the first light device. Each of the light devices may include a housing and a plurality of lights arranged and configured to emit at least one of red light and near infrared light. The first light device and the second light device can be coupled in a side-by-side orientation or a top-to-bottom orientation. The light therapy system can also be coupled to a mobile stand or a door stand.

Abstract: Methicillin-resistant Staphylococcus aureus (MRSA) possesses array of strategies to evade antibiotics through mutational inactivation, hiding inside host immune cells or concealing inside the biofilm in a sessile form. We report a drug-free approach to eradicate MRSA through blue-light bleaching of staphyloxanthin (STX), an anti-oxidative carotenoid residing inside the cell membrane of S. aureus. The photobleaching process, uncovered through a transient absorption imaging study and quantitated by mass spectrometry, decomposes STX and sensitizes MRSA to reactive oxygen species attack. Consequently, photobleaching using low-level blue light exhibits high-level synergy when combined with low-concentration of hydrogen peroxide. Antimicrobial effectiveness of this synergistic therapy is validated in MRSA culture, MRSA-infected macrophage cells, biofilm, and a mouse wound infection model. Collectively, these findings highlight broad applications of STX photobleaching for MRSA-infected diseases.

Abstract: Disclosed is a sterilization apparatus that can kill or inactivate sterilization target organisms present on a body or in the body without damage to human cells and has high energy efficiency. A sterilization apparatus is configured to irradiate a sterilization target organism on a body or in the body with light and thereby killing or inactivating the sterilization target organism. The sterilization apparatus includes: a light source configured to emit light having wavelengths within a wavelength range of 190 nm to 230 nm and a wavelength range of 230 to 300 nm; a power supply unit configured to supply power to the light source; a control unit configured to control the power supply unit; and an optical filter. The power supply unit is controlled by the control unit so that an irradiation amount of light having a wavelength within the wavelength range of 230 to 300 nm in one light irradiation is not more than 9 mJ/cm2.

Abstract: The present disclosure is directed to a phototherapeutic apparatus for focused UVB radiation and vitamin D synthesis and associated systems methods. In one embodiment a phototherapeutic apparatus can include a housing at least partially defining an irradiation zone, and an ultraviolet (UV) radiation source carried by the housing. The irradiation zone can be configured to accommodate at least a portion of a human patient. The phototherapeutic apparatus can further include a filter between the UV radiation source and the irradiation zone. The filter can be configured to at least substantially remove UV radiation outside of a predetermined spectrum centered at about 297 nm and having a bandwidth of at most 10 nm.

Abstract: The present invention relates to a dermatological treatment apparatus. Such dermatological treatments include but are not limited to hair removal, treatment of acne and lesions and also skin rejuvenation. The apparatus comprises a housing; a light emitting source provided in the housing arranged to emit light energy along an energy pathway to external of the device; and a filter arrangement positioned in the energy pathway having at least a first and a second light energy filtering portion together combining to span across the energy pathway for filtering the light energy passing to external of the device.

Abstract: An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

Abstract: A display panel including a plurality of pixels including a first pixel including a first blue sub-pixel, and a second pixel including a second blue sub-pixel, the second blue sub-pixel being configured to emit light having a wavelength different from that of the first blue sub-pixel and being adjacent to the first pixel.

Abstract: Ocular devices are provided for placement in the upper fornix of the eye and having a body that encompasses a low-level light source, an energy source, a microcontroller, and an antenna for delivering a programmable, fade in-out, light therapy regimen to treat neurological and ophthalmic diseases and disorders. In one embodiment the ocular device delivers a programmable green light therapy to reduce elevated intraocular pressure (IOP) and retinal hypoxia during the nocturnal period, that is, when these risk factors are at their highest level especially in glaucoma, age-related macular degeneration and diabetic retinopathy patients.

Abstract: A light control system having a central control engine, at least one light sensor, and at least one light source. The central control engine is configured to receive illumination data from the light sensor. The light data represents an actual light profile. The central control engine is configured to retrieve a target light profile for a user and adjust an illumination of the light control system based on the target light profile for the individual user.

Abstract: Systems and methods are provided for treating or preventing carbon monoxide poisoning. In particular, systems and methods are provided for a phototherapy treatment or prevention system that delivers light radiation to a patient's body to photodissociate carbon monoxide from hemoglobin.

Abstract: Provided is an image analysis device, an image analysis method, and an illumination device to efficiently acquire an image to be suitably used to analyze skin. An image acquisition unit is included, the image acquisition unit including an illumination unit including a light emitting unit in which a plurality of light emitting elements including at least a light emitting element that emits visible light and a light emitting element that emits invisible light are packaged, and an image pickup unit that captures an image of reflection light generated by causing irradiation light emitted from the illumination unit to be reflected by an analysis target. The present disclosure is applicable to, for example, a device for analyzing human skin.

Abstract: A method of treating dry eye includes delivering light energy from outside an eyelid toward the eyelid, and maintaining the delivery of the light energy toward the eyelid for a period of time to soften an obstruction of at least one meibomian gland. The light energy may be delivered specifically to the obstruction in the at least one meibomian gland without physically contacting the at least one meibomian gland, or the light energy delivered toward the eyelid may conductively apply heat to the meibomian gland to melt the obstruction. A corresponding apparatus includes a light energy source positionable outside an eyelid and configured to deliver the light energy from outside an eyelid toward the eyelid, and a controller configured to control the light energy source to maintain the delivery of the light energy toward the eyelid for a period of time to soften the obstruction.

Abstract: A light fixture, e.g., as an artificial skylight, in which light within a region defined by x, y color coordinates (0.37, 0.34), (0.35, 0.38), (0.15, 0.20), and (0.20, 0.14) exits a first light engine, and light within a region defined by coordinates (0.29, 0.32), (0.32, 0.29), (0.41, 0.36), (0.48, 0.39), (0.48, 0.43), (0.40, 0.41), and (0.35, 0.38) exits a second light engine. Also, light fixtures in which a second light engine comprises a sidewall, and light exiting a first light engine passes through space defined by the sidewall; light fixtures in which first and second light engines are able to output light providing different CS values at a luminance; light fixtures in which light incident on a surface of the fixture and cumulative light exiting the fixture have different color points; light fixtures in which light distribution characteristics of light engines differ; and/or other features. The invention also relates to corresponding methods.

Abstract: A multi-function device for skin treatment is provided, which includes: a main body comprising a lower base, a cover coupled to an upper portion of the lower base, and a main case seated on the lower base; an IPL generator comprising: an IPL power unit comprising a main power case mounted on the main case, and a main power board housed in the main power case; an IPL coolant circulation device mounted on the main case; and an IPL connector attached to the main case, and coupled to: an IPL connection cable; a vacuum suction unit connected to an IPL handpiece and generating vacuum suction pressure; a suction cable connected to the vacuum suction unit; and a coolant connection cable connected to the IPL coolant circulation device; an IPL handpiece connected to the IPL connection cable and performing IPL treatment while being in contact with skin; a high frequency generator comprising a high frequency control board mounted on other side of the main case, and a high frequency power connected to the high frequency c

Abstract: Method, system and computer program product are provided for estimating a circadian phase of a subject by: obtaining a sensed biological signal for the subject; and using, by one or more processors, adaptive frequency tracking to adaptively estimate the circadian phase of the subject from the sensed biological signal. Circadian phase estimation may be accelerated by providing a feedback loop for the adaptive frequency tracking, which utilizes, in part, a circadian phase model in automatically ascertaining a phase correction for the adaptive frequency tracking. The circadian phase estimation may be used in automatically constructing a light-based circadian rhythm model for the subject using a linear parameter-varying (LPV) formulation, and once constructed, the circadian rhythm model for the subject may be used to provide light-based circadian rhythm regulation.

Abstract: Apparatus and methods are disclosed for treating allergic rhinitis (seasonal and perennial hay fever), by application of flash lamp radiation. The nasal cavity can be illuminated in a safe and effective manner, with non-coherent light from a flash-lamp or other suitable source. This illumination can be accomplished in any suitable manner, including by use of a handheld device. Such handheld embodiments may contain a power source (battery or AC), control circuitry, light source (flash-lamp or diode laser), lens (focusing or non-focusing), light filter, and/or fiber-optic for delivering light to the nasal cavity. Embodiments include using any suitable light energy, such as visible light in the red wavelengths with a power output of 1 to 10 Joules per cm2. The device can be pre-programmed to deliver a specified amount of light in a specified amount of time using multiple pulses (in the case of a flash lamp) or a continuous wave (in the case of a diode laser).

Abstract: A kit comprising a wearable lamp platform a frame for holding the wearable lamp platform in a fixed orientation spaced from the user's body, an adapter arranged and configured to couple a data acquisition device to the optical lens of the at least one port; and a power source controller electrically coupled to the wearable lamp platform provides a simple and elegant solution to providing economic, at-home skin condition analyses. The wearable lamp platform includes a plurality of treatment lamps arranged and configured to irradiate a portion of a wearer's body, and at least one port extending through the lamp platform from the outer surface to the inner surface. The at least one port has disposed therein an optical lens and a plurality of image-acquisition lamps disposed thereabout.