Abstract: A stent delivery system includes a stent having at least one eyelet and at least one rivet and a holder supporting the stent, wherein the holder includes a first section having a first diameter and a second section having a second diameter. A sheath covers the stent and the holder. The rivets are attached to each of the eyelets. A first inner diameter of the stent at the position of the rivets is smaller than a second inner diameter of the stent at other positions because the rivets protrude inwardly. A shoulder is formed on the holder due to the difference between the first diameter and the second diameter of the holder. The shoulder is positioned distally adjacent the rivets. The shoulder interferes with the protruding rivets, thereby restraining the longitudinal movement of the stent relative to the holder. Although the sheath is pulled back, the stent does not jump out of the stent delivery system.

Abstract: A medical implant, having a proximal and a distal end, that is preformed to assume a superimposed structure at an implantation site but can be made to take on a volume-reduced form making it possible to introduce it with a micro-catheter and a guide wire arranged at the proximal end, with the implant in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments. The implant has a tapering structure at its proximal end where the strings or filaments converge at a connection point.

Abstract: An angioplasty stent comprises a body comprising a plurality of successive segments connected in pairs by bridge means so that the successive segments can be oriented relative to one another for the purposes of bending of the body in any direction defined by a linear combination of respective orientation axes defined by the bridge connection means. During the radial expansion of the stent, the axial contraction of the segments resulting from the opening-out of the respective loops is compensated by axial projection of the bridge elements from the respective concave portions. The wall of the body comprises arms for supporting a lumen as well as regions which are selectively deformable during the expansion of the stent, the arms and the selectively deformable regions having different cross-sections and/or cross-sectional areas. At least one portion of the body may have a substantially reticulate structure, the branches of which define geometrical figures identifiable as fractals.

Abstract: The present invention relates to a medical device, and in particular, to a stent-based valve. The valve includes a radially expandable structural frame including an anchor structure having a first and a second open end, a connecting member having a first and a second end, and a cantilever valve strut having a first and a second end. The first end of the connecting member is attached to the second end of the anchor structure. The first end of the cantilever valve strut is cooperatively associated with the second end of the connecting member. The prosthetic valve further includes a biocompatible membrane assembly having a substantially tubular configuration disposed longitudinally about at least a portion of the connecting member. The membrane assembly has a first end having a first diameter and a second end having a second diameter, wherein the first diameter is greater than the second diameter. The first end of the membrane assembly is attached along the second end of the cantilever valve strut.

Abstract: A stent is made flexible along its length. The stent initially starts as a metal sheet. It is rolled in its central region to a specified wall thickness. Thereafter, the stent is photochemically etched to produce the desired cell pattern of the design of the stent. Then, the stent is folded and the metal is joined to give rise to a stent with multiple wall thickness. For instance, larger wall thicknesses at the end of the stent versus smaller wall thicknesses at its center. Various other possible manufacturing methods are useful with respect to this stent.

Abstract: A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

Abstract: Anastomotic stents for connecting a graft vessel to a target vessel, and methods of use thereof. The anastomotic stents of the invention are suitable for use in a variety of anastomosis procedures, including coronary artery bypass grafting. One embodiment of the invention comprises a large vessel anastomotic stent for use with large diameter target vessels such as the aorta or its major side branches. Another embodiment of the invention comprises a small vessel anastomotic stent for use on a target vessel which has a small diameter such as a coronary artery. Another aspect of the invention involves applicators for use with the stents of the invention.

Abstract: Single tubular woven or bifurcated prostheses are disclosed having varying diameters and tapered transitions. The prostheses comprise a seam along the tapered edges, thereby providing a substantially fluid-tight transition between sections or extents of the prostheses. The seam may be located at an edge where fabric of the prosthesis tapers from one diameter to a different diameter and/or at a point where the prosthesis splits such as a bifurcation. The seamed crotch may be used for tapered and non-tapered bifurcated grafts. The seam may be woven directly on a weaving loom or joined together after weaving is completed.

Abstract: The present invention provides anchoring mechanisms for tissue implants. The anchors are integrated as part of the structure of the implant and serve to resist migration of the implant from highly dynamic muscle tissue such as the myocardium of the heart. In implant devices configured as a flexible coil, various attributes of the coil may be altered to increase the anchoring capability of the device. The flexibility of the device may be increased to resist migration by changing the coil filament thickness, pitch or filament material. Alternatively, the end coil may be altered to have a broader cross-sectional profile in engagement with the tissue or may include an anchoring barb. Additionally, methods of implanting a tissue implant device are provided.

Abstract: The invention provides an attachment member for anchoring a graft system at a desired location in a vessel of a patient's vascular system. The attachment member comprises a cranial zone having a first radial strength, a caudal zone having a second radial strength, and an intermediate zone having multiple joining longitudinal struts located between and connecting the cranial and caudal zones. The intermediate zone has a third radial strength which is less than the first and second radial strengths, and the cranial and caudal zones are formed from a self-expanding material capable of expanding from a first delivery configuration to a second deployed configuration. The invention also provides an endovascular graft system, a method for deploying an aortic attachment member, and a method for repairing an aneurysm in an aorta.

Abstract: An endoluminal aneurysm treatment system of an expandable bypass prosthesis and an extension prosthesis with a flared distal portion which, upon expansion, frictionally engages the proximal end of the bypass prosthesis.

Abstract: An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in the longitudinal direction. The strength of the stent at a center section or at either end can be varied by increasing the mass of the struts forming each cylindrical element in that center section or end section relative to the lower mass struts in the remaining sections of the stent. Increasing the mass of the struts can be accomplished by, for a given strut thickness, increasing the width of the strut, or increasing the length of a cylindrical element.

Abstract: Continuously flat-woven implantable tubular prostheses have seamless woven sections which gradually change the number of warp yarns to smoothly transition, i.e., taper, from one diameter to another. Multi-diameter endoluminal grafts having a variety of shapes and configurations are made using a seamless weaving process without unacceptable voids or gaps in the tubular wall.

Abstract: A stent deployment system includes a catheter shaft, an expandable member mounted to the catheter shaft, and one or more stents or stent segments slidably positioned on the expandable member. The stent deployment system is adapted for deployment of stents or stent segments in very long lesions and in tapered and curved vessels. The stent deployment system facilitates slidable movement of a stent in a distal direction relative to the expandable member while inhibiting slidable movement in a proximal direction relative to the expandable member.

Abstract: A stent graft device has an upper main tubular portion dividing into two tubular limbs and is adapted for location in an aorta having an aneurysm. The stent graft device is well suited for an aorta having a restricted section having an inner diameter smaller than the sum of the inner diameters of the iliac arteries, which branch from the aorta. The diameters of the two tubular limbs are sufficiently small to allow for both tubular limbs to be deployed side-by-side in a fully expanded state within the restricted section without being constrained by the aorta inner surface. The limbs also have distal end portions having diameters larger than the diameters of limbs at the area near the restricted section for being retained within the iliac arteries.

Abstract: Continuously flat-woven implantable tubular prostheses have seamless woven sections which gradually change the number of warp yarns to smoothly transition, i.e., taper, from one diameter to another. Multi-diameter endoluminal grafts having a variety of shapes and configurations are made using a seamless weaving process without unacceptable voids or gaps in the tubular wall.

Abstract: The stent having a flexible self-expandable braided tubular wall having a proximal segment having an outer diameter, and a distal segment having an outer diameter smaller than the outer diameter of the proximal segment. An intermediate segment is formed between the proximal and distal segments, which forms a truncated cone of which the base is forming the proximal end of the intermediate segment and of which the top is forming the distal end of the intermediate segment. A covering layer is arranged within the tubular wall.

Abstract: Stent designs for use in peripheral vessels, such as the carotid arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements are generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portion and peak portions, the valley portion including alternating double-curved portions and U-shaped portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the U-shaped portions to connect the cylindrical element to the other adjacent cylindrical element. The designs include an eight crown and six crown stent which exhibit flexibility and sufficient radial strength to support the vessel.

Abstract: An implantable textile prosthesis includes a first woven section having a tubular branch wall defining a fluid passageway therethrough. The tubular branch wall includes an elongate tubular extent and an asymptotically flared tubular extent, which is asymptotic with respect to the tubular branch wall. The asymptotically flared tubular extent includes a weaving pattern having a plurality of warp yarns and fill yarns and incorporating a gradual change in the number of warp yarns with respect to the fill yarns to provide a seamless and substantially fluid-tight transition region along said flared tubular extent. The tubular branch wall may be sutured to an elongate tubular main wall to provide an implantable tubular textile prosthesis particularly useful in branched end-to-side anastomoses. The tubular main wall may be heat-settably arched to resemble the natural arch of the aorta.

Abstract: Anastomotic stents for connecting a graft vessel to a target vessel, and methods of use thereof. The anastomotic stents of the invention are suitable for use in a variety of anastomosis procedures, including coronary artery bypass grafting. One embodiment of the invention comprises a large vessel anastomotic stent for use with large diameter target vessels such as the aorta or its major side branches. Another embodiment of the invention comprises a small vessel anastomotic stent for use on a target vessel which has a small diameter such as a coronary artery. Another aspect of the invention involves applicators for use with the stents of the invention.

Abstract: A prosthesis, introducer device and a method for repair of an aortic aneurysm which is positioned at least partially in the ascending aorta (62). The prosthesis (3) has a proximal end (15) and a distal end (5) and is formed from a biocompatible material, the proximal end is adapted to be surgically fastened adjacent and around the aortic heart valve (60) of a patient and the distal end is adapted to extend into the descending aorta (66). The distal end has a distally extending exposed self-expanding stent (9). The introducer device can be deployed through an incision (75) in the thoracic arch (64) and extend down the descending aorta to place the distal end of the prosthesis first and then removed so that the proximal end of the prosthesis can be sutured in place around the aortic heart valve (60).

Abstract: An anchoring element including a replacement heart valve for the purposes of intraluminal anchoring of the heart valve element to mammalian hearts, the anchoring element having a small enough initial volume prior to its placement that it can be brought to its point of use using a catheter through a blood vessel and can be expanded there to its functionally correct dimensions. The anchoring element is shaped differently from a cylindrical shape such that it is connected to the aorta at the point of use at least in areas in a form-locked manner. This facilitates an especially good seating of the anchoring element containing the replacement heart valve.

Abstract: An endoluminal device for affixation to a wall of a body lumen having a neck region defined by a relatively narrow width and a shoulder region that diverges from the neck region to a relatively wider width. The device comprises a shoulder portion, which may be part of a bulbous portion, having a diameter profile that conforms to the shoulder region, and, in some embodiments, a plurality of affixation members in an area of the device that typically extends from a distal end of the device through the shoulder portion. In one embodiment, the device comprises an endograft for repair of an aneurysm, such as an abdominal aortic aneurysm (AAA). Methods of using the endograft to inhibit continued diametric expansion of the aneurysm and to inhibit endoleak formation and migration of the endograft are also described.

Abstract: The present invention modifies the compliance of a vascular system by providing an elastic member, capable of reducing peak pressure and blood flow from the heart. These embodiments further allow for reduction of peak systolic pressure while increasing diastolic pressure and flow. In one embodiment, the device consists of an anchoring stent, having an elastic member with a passage for blood flow. This device is implanted percutaneously into a desired vessel location. The elastic member begins to “give” when blood pressure reaches a desired level. Additionally, the spring constant of the elastic member may be externally modified to change the compliancy. By precisely modifying the properties of the elastic member, normal arterial compliancy may be restored.

Abstract: An endoluminal prosthesis (10) comprises a radially expandable tubular segment (12) having a first end (32), a second end (34), a lumen interconnecting the first end (32) and the second end (34). A connection portion (52) defines an opening in the tubular segment (12) in fluid communication with the lumen. The connection portion (52) includes a converging portion (54), an annular diverging portion (56) and an annular neck portion (58) interconnecting the converging portion (52) and the diverging portion (56).

Abstract: An inventive flanged graft for end-to-side anastomosis includes a graft with bifurcated flanges. The bifurcated flanges may be symmetrical or asymmetrical relative to one another. The type and size of flange to be used is determined by various factors such as identity of the receiving artery, position of the arteriotomy on the receiving artery, and lumenal diameter of the graft. The graft is preferably anastomosed to the receiving artery using continuous sutures to join the arteriotomy to the peripheral edges of the bifucated flanges. In an alternate embodiment, the inventive bypass graft includes a flared skirt which extends circumferentially about the tubular graft member. The flared skirt has an elliptical shape and is offset from a central longitudinal axis of the graft member.

Abstract: A tubular prosthesis is implanted at a target location within a body lumen by transluminally placing and embedding an expansible prosthesis body within a sealing layer. The sealing layer occludes at least a circumferential band within an interface region between the prosthesis body and the inner wall of the body lumen, thus providing for blockage of body lumen flow past the prosthesis. The sealing layer may be introduced prior to or simultaneously with the prosthesis body. A tubular prosthesis may be implanted in blood vessels, particularly to protect aneurysms.

Abstract: A stent and method for making the stent are provided. The stent comprises regions of differing numbers of braided filaments to provide a stent with different dimensions and/or properties in different regions along the stent length. A preferred stent comprises a first and second plurality of braided filaments each braided together. The second plurality of braided filaments is braided into the first plurality of braided filaments to form a region of different properties than the first. A preferred embodiment is a stent having a narrower diameter along a more flexible region and a broader diameter along a more rigid region. Also included is a method of constructing a braided stent in accordance with the above.

Abstract: Disclosed is a tubular endoluminal vascular prosthesis, useful in treating, for example, an abdominal aortic aneurysm. The prosthesis comprises a self-expandable wire support structure having a tubular main body support and first and second branch supports. The support structure may include sliding links to permit flexibility while maintaining patency of the central lumen. The branch supports may articulate with the main body to permit the branches to pivot laterally from the axis of the main body throughout a substantial range of motion. Exoskeleton components or barbs may be provided to resist migration and endoleaks.

Abstract: There is disclosed a method for configuring or reconfiguring branches in tubing in which the axes of at least two components of the branched structure are arranged askew.

Abstract: The invention provides vascular grafts and methods for implanting the same. In one aspect of the invention, there are provided vascular grafts that have a stepped down distal end. In another aspect, the invention provides vascular grafts having cuffs for attachment to a target blood vessel. In yet another aspect, the invention provides connectors for making end-to-end graft connections. The invention also provides methods for implanting vascular grafts that include inserting the distal end of a graft into the target blood vessel for positioning downstream of the incision site and methods that include shortening a graft by removing a medial portion of the graft and connecting the resulting graft pieces in an end-to-end manner.

Abstract: A ureteral device is provided for facilitating stone passage through a ureter or duct. An exemplary ureteral device includes a flexible, elongate body that defines a plurality of cages along the body. In a contracted state the cages have a reduced diameter. When an activation force is applied, the cages transform to an expanded state, thereby defining a plurality of void spaces. The void spaces are configured to receive an obstruction, such as a stone. The ureteral device can then be induced to the contracted state to compress the obstruction within the elongate, flexible body and then be removed from the obstructed passage. The ureteral device can be configured to have different numbers of elongate flexible members that define the cages.

Abstract: An endoluminal device including a prosthesis and at least one indicator member affixed to the prosthesis that can be remotely monitored to indicate a change in pressure or morphology of the prosthesis. The indicator member may be an optical fiber, a strain gauge, or a first material having a first magnetic resonance imaging (MRI) susceptibility value that contrasts with a second MRI susceptibility value of a second material that comprises one or more remaining members of the prosthesis. A prosthesis monitoring system includes an endoluminal device as well as a subcutaneous electronics package and external electronics. Methods of detecting endoleaks or changes in morphology involve implanting an endoluminal device with the indicator and detecting information from the indicator.

Abstract: A medical device such as a stent made from single or double-butted tubing is disclosed. The butted tubing may be made from stainless steel or a nickel-titanium (nitinol) alloy. The butted tubing is created by thinning the material in between the ends of the tube through machining, drawing, cold working, laser cutting, or chemical etching. A strut pattern for a stent is laser cut into the butted tubing. The strut pattern for the stent includes rings connected by links. The end rings of the stent coincide with the double-butted ends of the tubing thereby increasing the hoop strength of those end rings.

Abstract: A stent and method of its use, the stent in its expanded configuration, exhibiting varying outward radial force along its length. In use, the expanded stent is of a tapered configuration which provides greater force in vessel regions requiring greater force and less force in regions requiring less. In particular the stent is useful in the ostium regions and at areas of bifurcation in vessels. Varying force over the length of the stent is achieved by varying the number of elements, the density of elements, the thickness of the elements making up the stent body, and maintaining a substantially metal to artery ratio in the expanded stent over its length.

Abstract: An implantable prosthesis is provided having a radially-expandable tubular body and at least one skirt extending therefrom. The skirt terminates in a peripheral edge, wherein at least portions of the peripheral edge are free and displaceable to a greater diameter of the tubular body. Thus, with the implantable prosthesis being a stent-graft used to treat an aortic aneurysm (e.g., abdominal aortic aneurysm (“AAA”)), the skirt may be used to inhibit Type I endoleaks upon its selective displacement in response to irregular aortic shaping and/or aneurysm neck expansion. The skirt may actively inhibit Type I endoleaks by forming a physical barrier against flow between the tubular body and the aortic wall. In addition, the skirt may passively inhibit endoleak formation by sufficiently restricting blood flow to allow coagulation and clot formation, which would act as a barrier against endoleakage.

Abstract: The invention provides an attachment member for anchoring a graft system at a desired location in a vessel of a patient's vascular system. The attachment member comprises a cranial zone having a first radial strength, a caudal zone having a second radial strength, and an intermediate zone having multiple joining longitudinal struts located between and connecting the cranial and caudal zones. The intermediate zone has a third radial strength which is less than the first and second radial strengths, and the cranial and caudal zones are formed from a self-expanding material capable of expanding from a first delivery configuration to a second deployed configuration. The invention also provides an endovascular graft system, a method for deploying an aortic attachment member, and a method for repairing an aneurysm in an aorta.

Abstract: Disclosed is a conduit that provides a bypass around a stenosis or occlusion in a coronary artery. The conduit is adapted to be positioned in the myocardium to provide a passage for blood to flow from a heart chamber to a coronary artery, at a site distal to the blockage or stenosis in the coronary artery. The conduit has a one-way valve positioned therein to prevent the backflow of blood from the coronary artery into the heart chamber.

Abstract: Continuously flat-woven implantable tubular prostheses have seamless woven sections which gradually change the number of warp yarns to smoothly transition, i.e., taper, from one diameter to another. Multi-diameter endoluminal grafts having a variety of shapes and configurations are made using a seamless weaving process without unacceptable voids or gaps in the tubular wall.

Abstract: A stent is a device that is adapted to be implanted into narrowed portions of hollow vessels of a body. The stent (1) comprises a stent body (2) that has at least two different wall thicknesses (WE, WH). The different wall thicknesses result in different flexibility characteristics of the stent in the longitudinal direction. Thus the stent according to the invention prevents irritations of the wall of the vessel in the area of the implanted stent, whereby the risk of restenosis in said area can be reduced considerably.

Abstract: A braided modular stent comprising a first component and a second component, each component comprising an hourglass-shaped interface having a reduced diameter section positioned between two sloped sections. Each sloped section extends between the reduced diameter section and one of a plurality of nominal diameter sections. The reduced diameter section has a greater radial strength than the nominal diameter sections. One of the components may have a sealing region, such as a circumferential elevation, for providing an endoleak-resistant seal between the stent and a body lumen. One exemplary method for fabricating a circumferential elevation comprises affixing a plurality of filaments, such as sutures, between overlaps of braided filaments in one region and overlaps in another region.

Abstract: A bypass conduit and related methods include implanting a bypass in the heart between a heart chamber and an at least partially occluded artery to directly flow blood from the chamber to the artery. The bypass conduit is configured to have a higher resistance to blood flow in a first direction than in a second direction without any active flow control mechanism. The bypass conduit may have a first end defining a first opening and a second end defining a second opening and a wall extending between the two ends that defines a lumen extending between the two openings. The ends and the wall of the conduit are configured to have a higher resistance to blood flow in a first direction than in a second direction.

Abstract: The present invention provides improved prostheses and methods for their endolumenal placement within body lumens, particularly blood vessels. In one embodiment, the prosthesis of the present invention having a plurality of radially expansible rings having, a plurality of beams connecting axially remote points on adjacent rings, and a plurality of expansion joints connecting axially proximate points on adjacent rings. The beams maintain the remote points at a fixed distance when the prosthesis is radially expanded and the expansion joints allow for relative movement of the proximate points during delivery of the prosthesis. The combination of the beams and expansion joints minimizes the risk of injury to the body lumen during delivery of the prosthesis to a target site and provides improved tracking capabilities.

Abstract: The stent comprises a flexible self-expandable braided tubular wall having a proximal segment having an outer diameter, and a distal segment having an outer diameter smaller than the outer diameter of the proximal segment. An intermediate segment is formed between the proximal and distal segments, which forms a truncated cone of which the base is forming the proximal end of the intermediate segment and of which the top is forming the distal end of the intermediate segment. A covering layer is arranged within the tubular wall.

Abstract: Continuously flat-woven implantable tubular prostheses have seamless woven sections which gradually change the number of warp yarns to smoothly transition, i.e., taper, from one diameter to another. Multi-diameter endoluminal grafts having a variety of shapes and configurations are made using a seamless weaving process without unacceptable voids or gaps in the tubular wall.

Abstract: A venous valve device and method of formation are described to provide antegrade blood flow in the deep venous vessels of the leg or in other venous vessels of the body having incompetent or irreversibly dysfunctional valves. A venous valve is formed in situ from autologous vein conduit not having a valve present locally. An overlap region is formed by attaching two opposing walls of the vein together in a generally axial direction forming two tubular regions. One region provides antegrade blood flow and the other region provides a sinus cavity that is filled during the initiation of retrograde blood flow. A valve cusp is formed by attaching vessel wall together forming a commissure that extends between the two overlap regions. A single valve cusp moves toward the sinus cavity to allow antegrade blood flow and moves away from the sinus cavity to block retrograde blood flow. Inlet and outlet transition regions can be formed to provide hemodynamic antegrade blood flow through the valve.

Abstract: A vascular prosthesis (50) comprises a tube (52) of material other than autologous vascular tissue, the tube having an end formation for surgical connection direct to an opening formed in an artery, the formation comprising an enlarged chamber (54) having a heel (56) and a toe (58) at opposite ends of a first longer diameter parallel to the axis of the tube and a second shorter transverse diameter the enlarged chamber serving to promote localised movement of blood having a non-laminar nature with a shear stress inducing relationship to receiving arterial wall.

Abstract: The present invention concerns a novel stent and a method for communicating oxygenated blood directly from the left ventricle to the coronary sinus to provide retrograde perfusion to the myocardium. The stent is placed substantially within the coronary sinus with its trailing end protruding into the right atrium and the leading end protruding into the left ventricle. The stent has a smaller passageway at or near the trailing (right ventricular) end and at or near the leading (left ventricle) end, and has a covering at the trailing end. The smaller passageway and the cover at the trailing end to promote retrograde flow into the venous system of the hear and specifically the myocardium of the left ventricle and to reduce a significant left-to-right shunt.

Abstract: The invention provides arteriovenous grafts and methods for implanting the same. In one aspect of the invention, there are provided arteriovenous grafts that have a stepped down venous end. In another aspect, the invention provides arteriovenous grafts having cuffs for attachment to a target vein. The invention also provides methods for implanting arteriovenous grafts that include inserting the venous end of a graft into the target vein for positioning downstream of the venotomy site.

Abstract: The present invention relates to medicine and more particularly to neurosurgery, and can be used in the operative treatment of patients with parasagittal meningiomas. The present invention is directed to the provision of radical removal of a parasagittal meningioma, restoring and securing natural blood flow, obviating recurrent parasagittal meningioma. The object is accomplished by that semicircular incisions of the dura mater circumscribing the tumor contour are made toward the base of the upper sagittal sinus, the tumor is removed as a single block together with a segment of the upper sagittal sinus and a portion of the falx cerebri, whereafter the removed segment of the upper sagittal sinus is replaced with an implant prosthesis ensuring physiological blood flow. The prosthesis is a cynlindrical tubular member in which the end parts are provided with smooth, curvilinear, gently sloping bevels made on its internal generating surface or on both internal and external surfaces thereof.