Abstract: A graft ligament anchor comprises a graft ligament engagement member disposed in an opening in a bone, the graft ligament engagement member being arranged to receive a graft ligament alongside the engagement member, and a locking member for disposition in the opening, and at least in part engageable with the graft ligament engagement member. Movement of the locking member in the opening causes the locking member to urge the engagement member, and the graft ligament therewith, toward a wall of the opening, to secure the graft ligament to the wall of the opening.

Abstract: A whip stitched graft construct and method of formation. The whip stitched graft construct includes a plurality of tendon strand regions or soft tissue grafts placed together so that at least a portion of the plurality of the tendon strand regions are stitched together by employing multiple suture passes placed according to a whip stitching technique. Preferably, the multiple suture passes start at about the mid length of the plurality of tendon strand regions and are advanced toward one of the free ends of the tendon strands. The whip stitched graft construct is provided with at least two regions, one region formed of at least a plurality of tendon strand regions tied and whip stitched together, and the other region formed of untied segments of the plurality of tendon strands.

Abstract: A reconstruction system and associated techniques for soft tissue repairs and repair augmentation. The reconstruction system is an internal soft tissue brace formed of at least one fixation device (for example, anchors or screws) and a replacement/reinforcement construct (for example, a suture construct in the form of a suture tape such as FiberTape® or a collagen tape or a suture with biological material or a collagen coated material, or a collagen patch, or a biological construct such as Arthroflex). The reinforcement construct and fixation devices may be used as a suture repair alone (to replace the ligament or tendon), or in conjunction with other traditional soft tissue repair procedures, acting as a reinforcement system for the repaired soft tissue.

Abstract: A tendon fixation anchor is designed for being received in a bone channel and includes at least one first through-hole which extends transversely to an insertion direction of the anchor. The tendon fixation anchor can be inserted into a bone channel. A transplant tendon (TT) to be fastened can be led through the at least one first through-hole.

Abstract: A system for installation of a graft ligament support block is provided. The system includes an installation tool having a holder including a shaft having a handle at a proximal end and a distal end configured for selectively engaging the graft ligament support block. The installation tool further includes a drill guide including an outrigger having a bore formed on its distal end for selectively receiving a drill sleeve and a proximal end configured to selectively engage the holder. Also provided is a kit for use in reconstructing a ligament. The kit includes an installation tool including a holder and a drill guide, a drill sleeve, a guidewire, one or more drills, one or more graft ligament support blocks and one or more transverse fixation pins.

Abstract: A method and construct for joint repair in which attachment of a double bundle graft ligament approximates anatomic orientation using interference fixation in a single bone tunnel. The double bundle graft features separable strands. A threaded screw is inserted between the separable strands and provides interference fixation of the graft against radially opposing walls defining the bone tunnel. Attachment of the graft using separated strands more closely approximate the configuration of the native ligament. The resulting reconstruction exhibits mechanical functionality that more accurately mimics that of the intact joint, with a minimum of associated tissue morbidity.

Abstract: Various methods and devices are provided for a graft fixation device for fixing a graft member within a bone tunnel. In one embodiment, a graft fixation device is provided having a radially expandable sheath adapted to be disposed within a bone tunnel, and a sheath expander adapted to be received within the radially expandable sheath to expand the sheath and thereby anchor a graft between the sheath and the bone tunnel. In an exemplary embodiment, the graft fixation device is particularly useful to affix a graft within a femoral tunnel.

Abstract: Methods of generating and expanding proliferative, multipotent connective tissue progenitor cells from adult stem cells are provided. Also provided are methods of generating functional tendon grafts in vitro and bone, cartilage and connective tissues in vivo using the isolated cell preparation of connective tissue progenitor cells.

Abstract: A method and apparatus for fixing a ligament in a bone tunnel by cross-pinning the ligament in the bone tunnel.

Abstract: Disclosed herein is an improved Bone Tendon Bone graft for use in orthopedic surgical procedures. Specifically exemplified herein is a Bone Tendon Bone graft comprising one or more bone blocks having a groove cut into the surface thereof, wherein said groove is sufficient to accommodate a fixation screw. Also disclosed is a a method of harvesting grafts that has improved efficiency and increases the quantity of extracted tissue and minimizes time required by surgeon for implantation.

Abstract: The ability to advance soft tissue into bone without externalizing it is considered an improvement for those knowledgable in the art of soft tissue fixation into bone. The above device/implant fixates soft tissue directly, then allows for fixation through a bony hole or aperture into a tunnel or void. It does not require interference fixation (eg. with a screw, or similar implant that fills a bony tunnel with soft tissue interposed). However, it does not preclude subsequent fixation that relies on interference fixation. The claims of this application disclosure for direct soft tissue fixation and subsequent bony fixation using the features of the described device/implant and insertor, as described in detail, are novel in this setting.

Abstract: This reinforcing band (1) for restoring a soft tissue, such as a tendon or a ligament, comprises a textile component with at least one free edge (2, 4). In addition, the or each free edge is folded back into an inner volume of the textile component in such a way as to define an attachment edge (6, 8) suitable for attachment to the soft tissue.

Abstract: A system and method for sharing and absorbing energy between body parts. In one particular aspect, the system facilitates absorbing energy between members forming a joint such as between articulating bones.

Abstract: An implantable device for use in tissue and ligament repair comprising at least one knitted section and at least one single continuous fiber traversing the at least one knitted section, the at least one single continuous fiber forming a plurality of traverses extending through the at least one knitted section. The implantable device may comprise at least one single continuous silk fiber. The implantable device is suitable for use in a variety or reconstructive or support applications such as breast reconstruction, mastopexy, breast augmentation revision, breast augmentation support, standard breast augmentation, chest wall repair, organ support, body contouring, abdominoplasty, facial reconstruction, hernia repair, and pelvic floor repair.

Abstract: Disclosed herein are methods and devices for securing soft tissue to a rigid material such as bone. A tissue anchoring device is described that comprises an anchor body and a spreader such that tissue may be captured or compressed between outside surfaces on the anchor and inside surfaces of a bone tunnel to secure the tissue within the tunnel. An anchoring device is described that comprises an anchor body having compressible tabs with teeth, and a spreader that forces the compressible tabs into an expanded state when inserted into anchor body, facilitating engagement between bone and the teeth of the compressible tabs. Also described is an inserter tool that can be used to insert the anchor into bone and move the spreader within the anchor to expand the anchor and capture the tissue between the anchor and the bone. Methods are described that enable use of the bone anchoring device to secure a tissue graft into the tibial and femoral bones during anterior cruciate ligament (“ACL”) reconstruction.

Abstract: A scapholunate dissociation/instability construct including an anchor having a proximal end and a distal end, and a threaded internal bore which may communicate with an eyelet at the distal end. The anchor is provided with two lateral, parallel sides that are smooth and non-threaded, and adjacent to sides that are provided with a plurality of ribs or threads.

Abstract: A biologic diarthrodial joint includes an artificial subchondral bone shaped in the form of a joint replacement member and formed of an artificial fiber material. The artificial fiber material includes synthetic fibers formed in a fibrous network with the synthetic fibers arranged in multiple orientations. The artificial subchondral bone includes a polymer receiving component. An artificial cartilage polymer is cooperable with the artificial subchondral bone and engages the polymer receiving component. The artificial cartilage polymer has physical properties similar to that of native articular cartilage.

Abstract: A unitary hybrid solid-flexible wire pin with a leading portion composed of a solid, substantially rigid member and a trailing portion composed of a flexible component, the leading portion having a free first end and a second end, the trailing portion having a free first end and a second end, wherein the second end of the trailing portion and the second end of the leading portion are fixedly coupled to create the unitary hybrid solid-flexible wire pin. The unitary hybrid soli-flexible wire pin is used as a passing pin for tunnel reaming in anterior cruciate ligament repair.

Abstract: A unitary hybrid solid-flexible wire pin with a leading portion composed of a solid, substantially rigid member and a trailing portion composed of a flexible component, the leading portion having a free first end and a second end, the trailing portion having a free first end and a second end, wherein the second end of the trailing portion and the second end of the leading portion are fixedly coupled to create the unitary hybrid solid-flexible wire pin. The unitary hybrid solid-flexible wire pin is used as a passing pin for tunnel reaming in anterior cruciate ligament repair.

Abstract: A continuous loop and button construct and technique for ligament repair and fixation, including bone to bone, or soft tissue to bone. The continuous loop, which is attached to the button, is formed of a flexible material and is provided with at least one joined region (a bridged, stitched, bonded or knotted region) to form a closed loop figure-8 construct with proximal and distal openings with respect to the fixation device. The figure-8 construct (either bridged, stitched, bonded or knotted) is adapted for attachment to a bone block of a BTB graft, for example, and used for ligament reconstruction.

Abstract: A connective tissue scaffold including opposed first and second anchoring segments formed from a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to a longitudinal axis of the scaffold and a plurality of bioresorbable polymeric fibers oriented in a direction substantially transverse to a longitudinal axis of the scaffold. A central segment joins the first and second anchoring segments and includes a plurality of bioresorbable polymeric fibers oriented in a direction substantially parallel to the longitudinal axis of the scaffold. The scaffold can also a tissue particle and/or biological component.

Abstract: An apparatus and method for fixation of a soft tissue graft. The apparatus may include a member having a first surface and a second surface. Each of the surfaces extend a distance relative to one another. A member is operable to resist movement of the apparatus relative to an anatomical portion. An interference member may be provided to fixedly associate the apparatus with the anatomical structure.

Abstract: A device for surgically coupling a soft tissue graft into a tunnel of a bone. The device includes a first member and a second member. The first member includes a first graft-engaging surface extending from a first end to a second end of the first member. The second member includes a second graft-engaging surface extending from a first end to a second end of the second member. The first graft-engaging surface and the second graft-engaging surface define a graft-accepting through-passage with a longitudinal axis extending therethrough when the first member is secured to the second member.

Abstract: A method of coupling a first portion of an anatomy to a second portion of the anatomy includes coupling first and second bones of the anatomy with a bone-tendon-bone implant. The bone-tendon-bone implant has a first bone end, a second bone end and a replacement tendon between the first and second bone ends. The first and second bone ends are positioned in corresponding first and second bores of the first and second bones. The first bone end is secured to the first bone with a first bone anchor. A second anchor coupled to the bone-tendon-bone implant is passed through and outside the second bore. The second anchor is coupled to an adjustable suture construct having two adjustable suture loops. Tensioning at least one of first and second ends of the adjustable suture construct tensions the replacement tendon and positions the first bone relative to the second bone.

Abstract: A method of ligament reconstruction comprising forming a femoral tunnel and a tibial tunnel, forming a plurality of supplemental femoral tunnels through a sidewall of the femoral tunnel, and forming a plurality of supplemental tibial tunnels through a sidewall of the tibial tunnel. The plurality of supplemental femoral tunnels and plurality of supplement tibial tunnels providing a basis for suture material fixation of graft tissue/material over cortical bone.

Abstract: An anterior cruciate ligament (ACL) surgical repair technique involves the use of a single femoral and tibial tunnel and an implant that separates and positions two distinct bundles. This allows for the surgeon to create a more anatomic reconstruction with a procedure that is less technically demanding, can be performed using a transtibial or anteromedial approach, minimizes tunnel widening, and decreases operative time. The result is a strong fixation option for soft tissue grafts, with circumferential graft compression at the aperture, high pull-out strength, and ease of use. The graft bundles are positioned in a more anatomic orientation through the above noted single femoral and tibial tunnel.

Abstract: A surgical screw for anchoring a flexible member to a bone. The screw may include a primary thread having a continuous helical ridge that curves around the shaft of the screw. A set of secondary threads may be disposed on, and follow, the continuous helical ridge around the screw. The set of secondary threads may have the same periodicity as the primary thread. The primary thread may comprise both a sharp portion and a blunt portion to prevent damage to the flexible member.

Abstract: A graft construct formed of a plurality of single tendon strands or soft tissue grafts placed together so that at least a portion of one of the single tendon strands is wrapped around a portion of another of the single tendon strands by employing suturing, for example. The graft construct is provided with at least two regions, one region formed of at least a plurality of tendon strands tied together, and the other region formed of loose segments of the plurality of tendon strands.

Abstract: A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. A collapsible tube is positioned about the suture. Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel and the collapse of the tube to form an anchor.

Abstract: The present invention relates to a method for treating a first biological soft tissue. A biological soft tissue implant is attached to a first damaged biological soft tissue such that the biological soft tissue implant is capable of interacting with a second biological soft tissue or bone to prevent the first biological soft tissue from retracting beyond a predetermined position.

Abstract: An intervertebral connection system wherein the bone anchor has a helical configuration.

Abstract: A soft tissue fixation system, most typically applicable to orthopedic joint repairs, such as anterior cruciate ligament (ACL) knee repair procedures, comprises an implant which is placeable in a tunnel disposed in a portion of bone, wherein the tunnel is defined by walls comprised of bone. A first member is deployable outwardly to engage the tunnel walls for anchoring the implant in place in the tunnel, and a second member is deployable outwardly to engage tissue material to be fixed within the tunnel. The second member also functions to move the tissue material outwardly into contact with the tunnel walls to promote tendon-bone fixation. Extra graft length is eliminated by compression of the tendon against the bone at the aperture of the femoral tunnel, which more closely replicates the native ACL and increases graft stiffness. The inventive device provides high fixation of tendon to bone and active tendon-bone compression.

Abstract: The invention relates to a system for controlled loading of a reconstructed human or animal tissue during the healing phase, comprising an anchor element (10) for implanting in a first bone (50), at least one connecting element (20), and one retaining element (30) for the at least one connecting element (20) on a second bone (40). The anchor element (10) and/or the connecting element (20) and/or the retaining element (30) are made of self-dissolving bioresorbable material.

Abstract: The canine ligament bone anchor of the invention includes a first femoral tunnel, a transverse femoral tunnel in communication with the first femoral tunnel, the first femoral tunnel and the transverse femoral tunnel forming a chamber, an end portion of a graft positioned through the first femoral tunnel and into an inner portion of the transverse femoral tunnel, and a set bone cement disposed in the chamber.

Abstract: An adjustable suture-button construct for ligament reconstruction. The construct is a knotless, adjustable, flexible suture loop, a first fixation device (a free or removable slotted button) and optionally a second fixation device (a fixed, non-removable button). Suture ends of the knotless suture loop provide a variable-length graft support that can be adjusted prior to, during, or after deployment of the constructs. The removable, detachable fixation device is provided with attachment feature(s) to permit assembly onto the adjustable loop. The removable, detachable fixation device is attached to the tibia end of the loop construct after the loop construct is passed through the tibial tunnel (i.e., once the loop exits the anterior tibia cortex). If a fixed, non-removable button is employed, the fixed, non-removable button is securely attached (by stitching, for example) to the graft.

Abstract: A ligament incorporated into a prosthetic joint exhibiting a plasticized, elongated and deformable material. A fibrous material is internally disposed within the deformable material, the fibrous material terminating in first and second enlarged bead portions arranged in proximity to enlarged pocket defined ends associated with the deformable materials. First and second bones define a joint region therebetween, the deformable end pockets and bead portions being inserted through associated holes defined in joint proximate locations associated with the bones, so that actuation of a projection location of the fibrous material causes the bead portions to outwardly deflect the end pockets, resulting in the ligaments being anchored in place between the bones.

Abstract: Systems and methods for ligament reconstruction provides an implant configured to position ligaments in the anatomic positions to thereby to restore the native anatomy and function of the reconstructed area. The implant includes a sheath, a first ledge, a second ledge, a first anchor and a second anchor. The sheath has an exterior surface and an interior surface, wherein the interior surface of the sheath forms a lumen configured to receive a sheath expander. The first ledge and the second are configured to separate the ligaments and acts as an anchor for the sheath in the bone tunnel. The first anchor and the second anchor are configured to engage the ligaments and be expandable outwards away from the lumen to provide fixation in a bone tunnel. When the implant receives the sheath expander, the ligaments can be separated, positioned, and secured in the bone tunnel.

Abstract: A ligament incorporated into a prosthetic joint exhibiting a plasticized, elongated and deformable material. A fibrous material is internally disposed within the deformable material, the fibrous material terminating in first and second enlarged bead portions arranged in proximity to enlarged pocket defined ends associated with the deformable materials. First and second bones define a joint region therebetween, the deformable end pockets and bead portions being inserted through associated holes defined in joint proximate locations associated with the bones, so that actuation of a projection location of the fibrous material causes the bead portions to outwardly deflect the end pockets, resulting in the ligaments being anchored in place between the bones.

Abstract: Methods for spinal stabilization operative to prevent lateral bending, extension, and rotation across two or more adjacent vertebrae are described. Broadly, the method includes placing two or more anchors at each vertebral level, passing one or more sutures through each anchor at each level, applying tension to the sutures and joining the sutures in a cross-braced arrangement over the disc space between two or more vertebrae to prevent lateral bending, extension, and rotation of the spinal segment. The sutures can be welded in any combination of diagonal and vertical patterns across the adjacent vertebrae. In some embodiments, two or more sutures can be threaded through some of the suture anchors such that multiple vertebral levels can be joined in a cross-braced arrangement. Two or more sutures can also be used in multiple anchors in two adjacent vertebrae to provide additional reinforcement or stabilization across different portions of the two vertebrae.

Abstract: A surgical fastener system for acromioclavicular (AC) joint dislocations, includes a first fastener having an elongate body, and an inner pair of openings centered on the long axis of the body. A closed loop stitch passes through the openings, and the length of the stitch corresponds to the depth of a passage defined between the top of a first hole bored through a patient's clavicle, and the bottom of a second hole bored through the coracoid in axial alignment with the first hole. A second fastener has an elongate body arranged to slide under a portion of the loop stitch that protrudes from the top of the hole in the clavicle, after the first fastener is set beneath the coracoid and the stitch is pulled upward through the passage. In an alternate embodiment, the second fastener also has an inner pair of openings for passing and engaging the loop stitch.

Abstract: A system for use in reconstructing a ligament is provided. The system includes a graft ligament support block for supporting a graft ligament in a bone tunnel. The support block includes a body, a graft hole extending through the body transverse to a longitudinal axis and configured to receive a graft ligament therein, and a transverse fixation pin hole extending through the body transverse to the longitudinal axis and configured to receive a transverse fixation pin therein. The system further includes a stepped transverse fixation pin having a first portion at a distal end, a second portion at a proximal end, and an annular shoulder configured between the first portion and the second portion. The first portion, the second portion and the annular shoulder form a given profile in a cross-section of a given plane perpendicular to a longitudinal axis of the fixation pin.

Abstract: A method and apparatus for surgically coupling a soft tissue replacement into a tunnel of a bone are disclosed. The method includes forming a loop of a soft tissue or soft tissue replacement. A pair of prosthetics are coupled to the loop of soft tissue to form an artificial bone-tendon-bone graft. The prosthetics and soft tissue are then placed within a tunnel formed in a bone. The relative position of the prosthetic is then fixed with respect to the tunnel.

Abstract: An anchor assembly for autologous or artificial tendon grafts comprises an insertion element and a stabilizing element. The insertion element has a stem and a head containing an aperture large enough to receive a graft. The stabilizing element is adapted to be embedded in bone, and comprises a sleeve with a cavity arranged to receive and hold the insertion element stem. In use, the stabilizing element is affixed in the bone, and the stem of the insertion element is placed therein. A tendon graft may be secured to the insertion element either before or after its placement in the stabilizing element. Two such anchors may be linked with one or multiple grafts, in either a two-ply or four-ply arrangement.

Abstract: A novel cross-pin for use in ACL reconstructive surgical procedures. The cross-pin has an elongated body having a distal tapered end. A guide wire opening in the distal end is in communication with a tunnel contained in the distal end. There is a trough extending into the outer surface of the trough for receiving a guide wire. The trough is in communication with the tunnel.

Abstract: A fixing tool used in a ligament reconstruction operation includes a fixing member having a main body part provided with a through-hole and two spike parts which can be stricken into the bone and a fixing screw. The fixing screw includes a shaft part having a self-tap portion and a male screw portion, a head part, and a lumen. The fixing screw can be screwed into the bone plug in a state where a guide pin pierced into the bone plug penetrates the lumen of the fixing screw and a pulling member mounted to the bone plug and extended from the bone tunnel is being pulled. The fixing screw can adjust a tensile force of the tendon graft by adjusting the amount of screwing of the fixing screw into the bone plug after the head part of the fixing screw contacts the fixing member.

Abstract: A method for securing first and second tissues with a suture anchor. The steps include forming a borehole in the first tissue; threading a suture through the second tissue forming a loop in the suture with the tissue thereby secured in the loop, the loop defining two suture portions; attaching the two suture portions to the anchor whereby the two suture portions are threaded through the anchor and initially movable with respect to the anchor; and providing a force to a shaft of the anchor, the force causing clamping of the two suture portions in the anchor and deformation of a deformable portion of the anchor to cause the deformable portion to engage a wall of the borehole thereby to secure the suture anchor in the first tissue and the loop holding the second tissue to the suture anchor.

Abstract: An adjustable, knotless button/loop/needle construct for fixation of cranial cruciate ligament deficient stifle. The adjustable, knotless construct includes two fixation devices (for example, two buttons), at least one flexible, adjustable loop attached to at least one of the fixation devices (e.g., the buttons), and two needles (each needle being attached to one fixation device, e.g., the buttons). The adjustable, knotless construct has an adjustable loop length and allows adjustment in one direction while preventing or locking the construct from loosening in the opposite direction, due to applied tensile forces. The construct and technique of the present invention provides an improved knotless system for cruciate ligament repair.

Abstract: A line lock system may include a line routed through a plate. The plate may have an elongated body with a plurality of passageways. The line is routed to form at least one one-way slide so no knots are required. The system may include filaments routed through the passageways of the plate or around a dogbone feature of the plate. The filaments may be used to toggle the plate after passage through a hole to prevent withdrawal of the plate back through the hole. The system may include a line lock stabilizer or counter-tension tool to stabilize the line lock as the line is adjusted. The system may include a compression limiter to selectively reduce compression in the one-way slide to facilitate adjustment of the line. The line lock stabilizer, counter-tension tool, or compression limiter may be a filament.

Abstract: A system for single tunnel, double bundle anterior cruciate ligament reconstruction includes implant constructs and instruments. The implant constructs provide a combination of cortical fixation and bone tunnel aperture fixation. The implant constructs separate a graft into distinct bundles. The instruments are used to prepare shaped bone tunnels to receive the implant constructs and graft bundles. Methods for reconstructing the antero-medial and postero-lateral bundles of the anterior cruciate ligament may rely on single femoral and tibial tunnels and a single strand of graft.

Abstract: A strap for repairing the attachment between a bone and a soft tissue according to embodiments of the present invention includes an elongated flexible textile body including, along its longitudinal direction, first and second longitudinal parts, the first longitudinal part including a fixation mechanism, the fixation mechanism configured to mechanically cooperate with the second longitudinal part, after the second longitudinal part has been passed through at least the soft tissue, to form a loop around at least a portion of the soft tissue, wherein the fixation mechanism permits tightening of the loop to tension the elongated flexible textile body to hold the soft tissue in place with respect to the bone.