Annular Member For Supporting Artificial Heart Valve Patents (Class 623/2.38)
  • Publication number: 20110125258
    Abstract: The present invention concerns a cardiac valve prosthesis system (10; 40) for implantation into the body of a mammal. The prosthesis system (19; 40) comprises a valve (16) mounted on an stent element (18) to form a stented valve element (12), and an anchoring element (14) to be arranged within the aorta of the mammal to be treated with the prosthesis and spaced-apart form the stented valve element (12). Further, the anchoring element (14) comprises a cylindrical tube element composed of fabric (22) supported by a metal mesh, and the stented valve element (12) and the anchoring element (14) represent two constructional distinctive elements being associated by ligament-like connecting means (30; 50), such, that the connecting region (28) between the stented valve element (12) and the anchoring element (14) is generally free from foreign material.
    Type: Application
    Filed: December 28, 2010
    Publication date: May 26, 2011
    Applicant: NVT AG
    Inventor: Marcos Centola
  • Patent number: 7896913
    Abstract: The invention relates to an anchoring system for heart valve prostheses which can be implanted by introduction via the aorta without any major surgical operation. With the heart valve prosthesis according to the invention it shall be achieved that this can be safely and quickly guided through the aorta toward the heart, and can be fixed there. With this, hook-shaped elements are secured to the commissures of the heart valve prosthesis the hooks of which are guided in an outward direction through the heart valve prosthesis material.
    Type: Grant
    Filed: September 5, 2006
    Date of Patent: March 1, 2011
    Assignee: JenaValve Technology, Inc.
    Inventors: Christoph Damm, Carsten Weber, Stefan Risse, Volker Guyenot, Matthias Mohaupt, Gerd Harnisch, Peggy Dorrer, Markus Ferrari, Klaus Lang, Hans-Reiner Figulla
  • Patent number: 7887583
    Abstract: A heart valve implant has a body sized and configured to rest near or within a heart valve annulus. A plurality of spaced-apart retainers extend outwardly from the body to contact tissue near or within the heart valve annulus. The retainers are sized and configured to secure the body to the heart valve annulus. The implant can be secured, e.g., without the use of sutures.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: February 15, 2011
    Assignee: MVRx, Inc.
    Inventor: John A. Macoviak
  • Publication number: 20100185279
    Abstract: Apparatus for the affixing of prosthetic, mechanical devices to body tissue. Often referred to as a “surgical attachment ring.” At least a portion of the outside edge of said ring is substantially of a non-convex profile. The application may also characterised by the feature of pre-attached or pre-loaded sutures or by the presence of one or more suture—receiving passageways in the body of the ring.
    Type: Application
    Filed: July 31, 2007
    Publication date: July 22, 2010
    Inventor: Sujay Shad
  • Patent number: 7758640
    Abstract: A cardiovascular valve assembly comprising a base member that is affixed to a patient using conventional sutures or staples, and a replaceable valve member including a valve frame that supports a plurality of valve leaflets. The valve member mates with the base member, and can be detached from the base member for convenient replacement.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: July 20, 2010
    Assignee: ValveXchange Inc.
    Inventor: Ivan Vesely
  • Publication number: 20100145438
    Abstract: A prosthetic valve assembly configured to be intraluminally implanted into a lumen of a patient to replace a native deficient valve, the valve assembly comprising an outer support for expanding and anchoring against a lumen wall of the patient, a core valve support made of a collapsible and self-expanding material to expand and anchor into the outer support once anchored against the lumen wall, and a plurality of flexible leaflets fixed to the core valve support in a manner that the leaflets are independent from the outer support.
    Type: Application
    Filed: December 8, 2008
    Publication date: June 10, 2010
    Inventor: HECTOR DANIEL BARONE
  • Patent number: 7722667
    Abstract: A bioprosthetic heart valve includes an outer frame configured to attach to a tissue annulus of a heart and an inner bioprosthetic valve having an exterior shape which substantially matches an interior shape of the outer frame. The exterior shape of the inner valve mates in substantial alignment with the interior shape of the outer frame. An outer frame-inner valve attachment mechanism is configured to couple the inner valve to the outer frame.
    Type: Grant
    Filed: May 17, 2000
    Date of Patent: May 25, 2010
    Assignee: St. Jude Medical, Inc.
    Inventor: Eric S. Buchanan
  • Patent number: 7713298
    Abstract: Methods and devices are provided for support of a body structure. The devices can be adjusted within the body of a patient in a minimally invasive or non-invasive manner such as by applying energy percutaneously or external to the patient's body. The energy may include, for example, acoustic energy, radio frequency energy, light energy and magnetic energy. Thus, as the body structure changes size and/or shape, the size and/or shape of the annuloplasty rings can be adjusted to provide continued reinforcement. In certain embodiments, the devices include a shape memory material that is responsive to changes in temperature and/or exposure to a magnetic field. A material having enhanced absorption characteristics with regard to a desired heating energy may be used in order to facilitate heating and adjustment of the support device.
    Type: Grant
    Filed: May 6, 2005
    Date of Patent: May 11, 2010
    Assignee: MICARDIA Corporation
    Inventors: Emanuel Shaoulian, Shahram Moaddeb, Sanuel M. Shaolian
  • Publication number: 20100100176
    Abstract: A method and device for reducing paravalvular leakage upon implantation of a replacement heart valve is provided. The valve assembly includes a tissue or bioprosthetic heart valve attached to an anchoring structure. The anchoring structure includes an inlet rim that is substantially C-shaped in cross section to form a concave landing zone. The anchoring structure self-seats when implanted in the sinus of a patient with the proximal and distal ends of the C-shaped inlet rim pushed against the aorta to effectively prevent paravalvular leakage.
    Type: Application
    Filed: October 21, 2009
    Publication date: April 22, 2010
    Applicant: ATS Medical, Inc.
    Inventors: David Elizondo, Andrzej M. Malewicz, Matthew W. Weston, Keith E. Myers
  • Publication number: 20100070029
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Application
    Filed: October 6, 2009
    Publication date: March 18, 2010
    Applicant: Arbor Surgical Technologies, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Steven R. Bacich
  • Publication number: 20100030330
    Abstract: Devices and methods for reshaping a mitral valve annulus are provided. One device according to the invention is configured for deployment in the right atrium and is shaped to apply a force along the atrial septum. The device causes the atrial septum to deform and push the anterior leaflet of the mitral valve in a posterior direction for reducing mitral valve regurgitation. Another embodiment of a device is deployed in the left ventricular outflow tract at a location adjacent the aortic valve. The device may be expandable for urging the anterior leaflet toward the posterior leaflet. Another embodiment of the device includes a first anchor, a second anchor, and a bridge, with the bridge having sufficient length to reach from the coronary sinus to the right atrium and/or superior or inferior vena cava. In a further embodiment a device includes a middle anchor positioned on the bridge between the distal and proximal anchors.
    Type: Application
    Filed: August 1, 2008
    Publication date: February 4, 2010
    Applicant: Edwards Lifesciences Corporation
    Inventors: Donald E. Bobo, Stanton Rowe, Michael Popp, Seung Yi
  • Patent number: 7628804
    Abstract: Medical devices for implantation in a body vessel are provided. Each medical device comprises a main body, a valve, and a vessel engaging member. The vessel engaging member is disposed on an outer surface of the main body. Kits including a plurality of vessel engaging members for use with one or more valve members are also provided. The vessel engaging members have varying radial dimensions, allowing assembly of medical devices having varying radial dimensions. Methods of treating a patient using medical devices according to the invention are also provided.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: December 8, 2009
    Assignee: Cook Incorporated
    Inventors: Jacob A. Flagle, Brian C. Case, Andrew K. Hoffa
  • Patent number: 7611535
    Abstract: A fixation band for affixing a prosthetic heart valve to tissue having proximal and distal annular portions positionable relative to one another, the proximal and distal annular portions each having a proximal and distal sides, the proximal side of the distal annular portion and the distal side of the proximal annular portion being oriented toward one another, and a prosthetic heart valve being attachable to one of the distal side of the distal annular portion and the proximal side of the proximal annular portion; staples configured between the distal side of the proximal annular portion and the proximal side of the distal annular portion; and a compression device operative between the proximal and distal annular portions for selectively positioning the proximal and distal annular members toward one another for compressing the staples therebetween and deploying the staples into tissue so as to affix the prosthetic heart valve to tissue.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: November 3, 2009
    Assignee: Medtronic, Inc.
    Inventors: Steven B. Woolfson, Richard B. Streeter, Daniel C. Taylor, John R. Liddicoat
  • Publication number: 20090264997
    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve.
    Type: Application
    Filed: June 26, 2009
    Publication date: October 22, 2009
    Inventors: Amr Salahieh, Ulrich R. Haug, Hans F. Valencia, Robert A. Geshlider, Tom Saul, Dwight P. Morejohn, Kenneth J. Michlitsch
  • Publication number: 20090264989
    Abstract: A heart valve that can be expanded following its implantation in a patient, such as to accommodate the growth of a patient and the corresponding growth of the area where the valve is implanted, and to minimize paravalvular leakage. In one aspect, the invention may maximize the orifice size of the surgical valve. The invention includes expandable implantable conduits and expandable bioprosthetic stented valves. In one aspect of the invention, the valve may be adapted to accommodate growth of a patient to address limitation on bioprosthetic valve lifespans.
    Type: Application
    Filed: February 27, 2009
    Publication date: October 22, 2009
    Inventors: Philipp Bonhoeffer, Timothy R. Ryan
  • Publication number: 20090259307
    Abstract: Apparatus is provided for repairing a valve of a heart of a patient which includes an annulus and at least first and second leaflets. The apparatus includes an annuloplasty structure, a plurality of tissue anchors, and a plurality of flexible longitudinal guide members removably coupled to the structure. Each of the guide members is configured to facilitate anchoring of the annuloplasty structure to the annulus of the patient by a respective one of the anchors. The guide members are configured to be advanced toward the annulus simultaneously with the annuloplasty structure. Other embodiments are also described.
    Type: Application
    Filed: June 15, 2009
    Publication date: October 15, 2009
    Applicant: VALTECH CARDIO, LTD.
    Inventors: AMIR GROSS, IFTAH BEINART, ELIAHU ELIACHAR, NIR LILACH, RAM GROSSFELD, DMITRY GOLOM, GIDEON MEYER-BRODNITZ, ARNON MOSAIUF
  • Patent number: 7597711
    Abstract: A heart valve assembly includes a base including a multi-lobular annular shape within a plane, a valve member or other annular body including a multi-lobular shape complementary to the shape of the base, and cooperating connectors on the base and the annular body for connecting the annular body to the base. The base includes an anchoring ring, and a flexible cuff for attaching the base to a biological annulus. The base and the annular body include guides for aligning their multi-lobular shapes, e.g., visual, tactile, or other markers, or tethers that extend from the base that are slidable through the annular body. During use, the base is attached to a biological annulus, the annular body is directed adjacent the annulus, oriented such that the multi-lobular shape of the annular body valve member is aligned with the base, and the annular body is attached to the base.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: October 6, 2009
    Assignee: Arbor Surgical Technologies, Inc.
    Inventors: Michael J. Drews, Donnell W. Gurskis, Steven R. Bacich
  • Patent number: 7591826
    Abstract: A device, system and method provides mitral valve therapy. The device is implantable in the coronary sinus of the heart to partially encircle the mitral valve annulus. The device is elongated, is resilient, and has a preformed arched configuration. When the device is implanted in the coronary sinus, the device exerts a substantially radially inward force to the mitral valve to restore mitral valve annulus geometry.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: September 22, 2009
    Assignee: Cardiac Dimensions, Inc.
    Inventors: Clifton A. Alferness, David M. Kaye
  • Publication number: 20090222084
    Abstract: A prosthetic heart valve having spaced apart anchoring flanges that change shape when the valve is implanted and contact the surrounding annulus to prevent migration of the valve. The heart valve may be non-expandable and the anchoring flanges may provide the primary anchoring structure of the valve. Alternatively, the valve may be expandable wherein the anchoring flanges supplement the inherent anchoring capacity of the valve structure. The anchoring flanges are at least partly made of a material that increases in size, i.e., swells, due to absorption of body fluids. For instance, the anchoring flanges may be formed of an inner material that swells upon contact with body fluids enclosed by a cover. The anchoring flanges may be provided on an anchoring sleeve that changes shape to provide the spaced apart annular flanges for securing the valve around a fibrous annulus.
    Type: Application
    Filed: May 11, 2009
    Publication date: September 3, 2009
    Applicant: Edwards Lifesciences Corporation
    Inventor: Robert S. Friedman
  • Publication number: 20090210052
    Abstract: Described herein are systems and methods for operation of a prosthetic valve support structure (32) having additional reinforcement coupled with panels (36). Multiple support members (620) are distributed across the inner surface of the valve support structure (32) at regular intervals. Each support member (620) can include a looped portion (621) to act as a hinge (52). Each looped portion (621) is in a location coincidental with the interlace between adjacent panels (36).
    Type: Application
    Filed: June 20, 2007
    Publication date: August 20, 2009
    Inventors: David C. Forster, Brian Beckey, Brandon Walsh, Scott Heneveld
  • Patent number: 7569072
    Abstract: Heart valve attachment apparatus and methods that significantly reduce attachment times are provided. The apparatus and methods utilize a connector band to form an interface between a uni-directional valve and a tissue annulus. The connector band is secured to the tissue annulus by retention fingers.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: August 4, 2009
    Assignee: St. Jude Medical ATG, Inc.
    Inventors: Todd A Berg, William J Swanson, Jerry Grudem
  • Patent number: 7566343
    Abstract: A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.
    Type: Grant
    Filed: September 2, 2004
    Date of Patent: July 28, 2009
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Mark L. Jenson, William J. Drasler, Daniel M. Lafontaine
  • Publication number: 20090187241
    Abstract: The disclosure relates to frames suitable for prosthetic implantable valves, and methods of treatment with such frames, to regulate blood flow and to be compliant in percutaneous delivery and, upon implantation, configured to conform to the changing shape of the body vessel or vein. The frames include at least one anchoring member attached to a support member at one or more attachments, and a valve member, preferably a monocuspid valve leaflet, attached to the support member. Preferred frames include two anchoring members with the support member in between the anchoring members. The support member preferably has a semielliptical shape and extends diagonally to sealingly contact the wall of the body vessel.
    Type: Application
    Filed: January 22, 2009
    Publication date: July 23, 2009
    Applicant: Cook Incorporated
    Inventor: Jeffry S. Melsheimer
  • Publication number: 20090177271
    Abstract: The invention concerns a method for preauthentication of a first entity (10) by a second entity (1) communicating with each other through a wireless link, including the following steps: the second entity (1) emits (23?) a challenge value (c); if the first entity (10) receives (23) a challenge value (c?) it applies to the received challenge value a predefined transformation (g) known to the second entity, to obtain a first transformed value (r), then emits (24) the first transformed value obtained; and if the second entity receives (24?) a transformed value (r?) it compares (25?) the received transformed value to a second transformed value (r?) obtained by applying the predefined transformation (g) to the emitted challenge value, and estimates the preauthentication to be successful if the result of the comparison between the second transformed value obtained and the received transformed value is less than a predefined threshold (m).
    Type: Application
    Filed: September 29, 2006
    Publication date: July 9, 2009
    Inventor: Jean-Noel Fabiani
  • Publication number: 20090164006
    Abstract: A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart.
    Type: Application
    Filed: January 5, 2009
    Publication date: June 25, 2009
    Inventors: Jacques Seguin, Georg Bortlein
  • Publication number: 20090132037
    Abstract: The disclosure relates to support frames for prosthetic implantable valves. The support frames may include a plurality of symmetrically arrayed interconnected U-shaped member structures. Preferred support frames are tubular structures enclosing a longitudinal axis and including a plurality of U-shaped member structures facing a distal or a proximal end of the support frame. Each U-shaped member structure may be connected to a single longitudinally adjacent U-shaped member facing in an opposite longitudinal direction, as well as two laterally adjacent U-shaped members.
    Type: Application
    Filed: November 18, 2008
    Publication date: May 21, 2009
    Applicant: Cook Incorporated
    Inventors: Grant T. Hoffman, Sean D. Chambers, Ram H. Paul, JR.
  • Patent number: 7530997
    Abstract: A valve assembly (10) has a support ring (20) and a valve body (30). The valve body (30) is supported by the ring (20) and comprises an annular body portion (31) that is rotatably engageable with the support ring (20). The annular body portion (30) supports a plurality of leaflets (32) that are moveable relative to each other and the annular body portion (30) between: a closed position and an open position upon changes in pressure differential across the valve assembly (10).
    Type: Grant
    Filed: January 21, 2005
    Date of Patent: May 12, 2009
    Assignee: Advanced Surgical Design and Manufacture Limited
    Inventor: Gregory James Roger
  • Publication number: 20090118824
    Abstract: A heart valve prosthesis includes an annulus and a closing element having three leaflets. Hinge mechanisms are provided for attaching each leaflet to a top region of an interior surface of the annulus. In one example, the leaflets have convexo-concave surfaces and a non-uniform thickness. In another example, the top region of the interior surface has two sets of ledges which can be formed by intersecting three pairs of cylindrical surfaces. Ledges within each set are evenly spaced about the interior surface, a ledge in one set alternating with a ledge in the other set. In a further example, a bottom region of the interior surface is formed by intersecting three cylindrical surfaces.
    Type: Application
    Filed: April 28, 2006
    Publication date: May 7, 2009
    Inventor: Alexander Samkov
  • Publication number: 20090112311
    Abstract: The present invention provides devices, systems and methods for closing a paravalvular leak. In accordance with one embodiment, a medical device includes at least one multicellular frame member configured to be implanted at a paravalvular leak. The medical device further includes at least one tissue in-growth member associated with the frame member, the tissue in-growth member being configured to promote tissue growth and permanently maintain the frame member at the leak. The frame member may be self expanding device formed, for example, of a shape-memory alloy. The tissue in-growth member may be formed from a polymer material. In one particular embodiment, the frame member may be a substantially tubular structure and the tissue in-growth member may be disposed within an interior space defined by the tubular structure. In another embodiment, the frame ember may be a substantially flat or planar structure.
    Type: Application
    Filed: October 17, 2008
    Publication date: April 30, 2009
    Applicant: COHEREX MEDICAL, INC.
    Inventors: Scott D. Miles, Clark C. Davis, Richard J. Linder
  • Publication number: 20090105813
    Abstract: Valve devices, methods of making valve devices, and methods of treating various venous-related conditions, disorders and/or diseases are described. In one embodiment, a valve device includes an expandable support frame and a bioprosthetic valve attached to the support frame. The bioprosthetic valve comprises a leaflet and a contiguous wall portion harvested from a multi-leaflet xenogeneic valve. The contiguous wall portion includes the attachment region where the leaflets attaches to the vessel wall and, in some embodiments, includes the natural margins of attachment between the leaflet and vessel wall.
    Type: Application
    Filed: October 16, 2008
    Publication date: April 23, 2009
    Inventors: Sean Chambers, Ram Paul, Norman Jaffe
  • Publication number: 20090076599
    Abstract: A valve holder assembly for delivering a prosthetic heart valve having a stent base an multiple extending commissure posts. The valve holder assembly includes a holder and a rotor that is rotatable relative to the holder.
    Type: Application
    Filed: September 16, 2008
    Publication date: March 19, 2009
    Inventor: Cathleen A. Bergin
  • Patent number: 7503930
    Abstract: Implantable prosthetic valve systems and methods for implanting them are provided. Magnets are employed within one or more components of the valve systems to facilitate anchoring of the prosthetic valve at a target implant site, delivery of the prosthetic valve to the target implant site or both.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: March 17, 2009
    Assignee: Medtronic, Inc.
    Inventors: Adam Sharkawy, Mark Foley, Darin Gittings, David Cole, Sam Crews
  • Publication number: 20090054974
    Abstract: The present invention provides a valve configured for insertion on the proximal and distal sides of a heart valve annulus to replace the heart valve of a patient. The valve comprises a first substantially annular portion adapted to be positioned on a proximal side of the annulus of a patient and a second substantially annular portion adapted to be positioned on a distal side of the annulus of a patient, wherein at least one of the first and second substantially annular portions is movable towards the other portion to a clamped position to clamp around the annulus. The second portion has a flow restricting portion extending therefrom and is movable between a first position to permit the flow of blood and a second position to restrict the flow of blood. In one embodiment, the valve has a suture joining the first and second portions to draw the first and second portions into closer proximity and a cinch member to secure the suture to maintain the first and second portions in the clamped position.
    Type: Application
    Filed: October 22, 2008
    Publication date: February 26, 2009
    Inventors: James F. McGuckin, JR., Peter W.J. Hinchliffe
  • Publication number: 20090054973
    Abstract: A prosthetic mitral heart valve having four separate flexible leaflets. The heart valve includes a support frame that may be non-circular, for example elliptical or “D-shaped”. The support frame may have an undulating outflow edge defined by four inflow cusps and four outflow commissures to which each of the flexible leaflets attaches. The support frame may comprise an undulating wireform and a surrounding stent defining a structure having four cantilevered posts projecting in the outflow direction to support the four leaflets. The heart valve is designed to be secured in the annulus and function as a standalone unit without papillary muscle connections to the leaflets. The four leaflets may be arranged in two opposed pairs, one pair being smaller than the other pair. The larger pair of leaflets may be identical, or differently sized. Existing sizes of heart valve leaflets may be utilized with the smaller leaflets being at least two leaflet sizes smaller than the larger leaflets in odd millimeter increments.
    Type: Application
    Filed: October 31, 2008
    Publication date: February 26, 2009
    Applicant: Edwards Lifesciences Corporation
    Inventor: Derrick Johnson
  • Publication number: 20090043381
    Abstract: Methods, devices and systems are disclosed to treat atrioventricular valve regurgitation accessed through the vasculature, and by standard and minimally invasive surgical techniques. Isolated leaflet fixation and annulus treatment systems are developed.
    Type: Application
    Filed: October 5, 2005
    Publication date: February 12, 2009
    Inventors: John A. Macoviak, Robert T. Chang, Alden Harken, Timothy R. Machold, David A. Rahdert
  • Publication number: 20090030435
    Abstract: Methods, devices and systems facilitate retention of a variety of therapeutic devices. Devices generally include an anchoring element, which has been designed to promote fibrotic ingrowth, and an anchored device, which has been designed to firmly engage the complementary region of the anchoring element. The anchoring element may be placed in a minimally invasive procedure temporally separated from the deployment of the anchored device. Once enough time has passed to ensure appropriate fixation of the anchoring element by tissue and cellular ingrowth at the site of placement, the anchored device may then be deployed during which it firmly engages the complementary region of the anchoring element. In this manner, a firm attachment to the implantation site may be made with a minimum of required hardware. Some embodiments are delivered through a delivery tube or catheter and while some embodiments may require laparoscopy or open surgery for one or more of the placement procedures.
    Type: Application
    Filed: August 15, 2008
    Publication date: January 29, 2009
    Applicant: TheraNova, LLC
    Inventors: Daniel Rogers BURNETT, Shane MANGRUM
  • Patent number: 7473275
    Abstract: A flexible support frame for a prosthetic heart valve having commissure tips that are shaped to even out stresses imposed during use. The support frame is an elongated wire-like element formed by a plurality, typically three, of arcuate cusp regions on an inflow end alternating with the same number of commissures terminating in tips on an outflow end. The commissure tips are elongated relative to more simple shapes. The commissure tips may be shaped with a complex curve having two enlarged convex flexure portions separated by a concave bridge portion at the midpoint of the commissure tip. The support frame may be fabricated by separating a two-dimensional blank from a sheet and then converting the blank into a three-dimensional support frame shape. The cross-sectional thickness of the support frame may be variable, such as by adjusting the thickness of the pattern of the two-dimensional blank in the sheet.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: January 6, 2009
    Assignee: Edwards Lifesciences Corporation
    Inventor: Salvador Marquez
  • Publication number: 20080300676
    Abstract: A heart valve prosthesis disclosed in two- and three-leaflet versions includes a ring-shaped body, leaflets, and leaflet turn stops. For the two-leaflet version, the stops represent two pairs of prominences located on a body end surface facing the blood down-flow. The first pair has internal surfaces, at least partially made flat, adapted to interact with flat sections of the leaflets to restrict the return blood flow in the closed position. The first pair is equipped with at least two rests interacting with a leaflet top surface facing the blood down-flow in its open position determining a leaflet turning angle. Each prominence of the second pair is located opposite a portion of the lateral surface of the corresponding leaflet most distant from a leaflet central surface and can interact with its internal surface with that part of the lateral surface during opening of the heart valve prosthesis.
    Type: Application
    Filed: December 8, 2006
    Publication date: December 4, 2008
    Inventors: Alexandr P. Melnikov, Denis A. Melnikov
  • Publication number: 20080300677
    Abstract: The effects of acute left ventricular heart failure are mitigated by temporary support of the cardiac function through use of either one or both of an expendable temporary one-way valve positioned in the aorta, having a collapsible frame that is expanded upon deployment, and/or a temporary dilation device positioned in the descending aorta for expanding upon deployment to increase the diameter of the associated portion of the aorta. When used together, the dilation device is positioned distal to the temporary one-way valve.
    Type: Application
    Filed: October 19, 2007
    Publication date: December 4, 2008
    Inventor: Howard L. Schrayer
  • Patent number: 7458987
    Abstract: Described are vascular valve devices for implantation in a patient. The vascular valve devices are designed to compensate for the retraction characteristics of a remodelable material used to form one or more leaflets. Alternatively, or in addition, the devices are designed to reduce retraction of the remodelable leaflet-forming material. Further described are methods for preparing and using these vascular valve devices.
    Type: Grant
    Filed: October 27, 2005
    Date of Patent: December 2, 2008
    Assignee: Cook Incorporated
    Inventors: Brian C. Case, Jacob A. Flagle, Michael L. Garrison, F. Joseph Obermiller, Dusan Pavcnik
  • Publication number: 20080281411
    Abstract: The present invention relates to an assembly comprising: a ring having anchoring elements for attaching the ring in a passage surrounded by body tissue, in particular blood vessel tissue. An applicator for fitting the ring in the passage; in which the anchoring elements have an anchoring position in which they protrude with respect to the ring, and in which the anchoring elements comprise a memory material, such as a memory metal or memory polymer, and are designed so that they can be bent from an anchoring position counter to a spring force into a fitting position and can be frozen in this fitting position by a temperature treatment in order to bend the anchoring elements back from the fitting position by the effect of this spring force into the anchoring position when a predetermined threshold temperature is exceeded, and in which the applicator is provided distally with a carrier for carrying the ring.
    Type: Application
    Filed: March 29, 2005
    Publication date: November 13, 2008
    Inventor: Eric Berreklouw
  • Publication number: 20080275540
    Abstract: An artificial heart valve and weaving method thereof are disclosed. The valve stent includes a tubular stent (10), valve leaflets (33), sealing membranes (351, 354), x-ray opaque markers (311, 312) and flexible connecting loops (41). The middle segment (15) of the net stent (10) is tubular or drum-shaped, or provided with radial protrusion structures (153), or provided with outer annular structures (155), or provided with outer free tongues (156), or provided with radial protrusion structures (153) and outer free tongues (156). The stent can be made by up and down interweaving the same one elastic metal wire, and also can be made by up and down interweaving different elastic metal wires.
    Type: Application
    Filed: November 7, 2006
    Publication date: November 6, 2008
    Inventor: Ning Wen
  • Publication number: 20080262609
    Abstract: Apparatus is provided for repairing a valve of a patient, the valve including an annulus and at least first and second leaflets. The apparatus includes at least a first discrete segment and a second discrete segment of an annuloplasty structure, each segment being shaped to provide a respective lateral wall, each lateral wall being shaped to define at least one lumen of the respective segment. The apparatus further includes at least a first and a second control wire, each control wire configured for sliding advancement through both the first and second segments. The first control wire is configured to control a relative disposition of a first end of the first segment and a first end of the second segment. The second control wire is configured to control a relative disposition of a second end of the first segment and a second end of the second segment. Other embodiments are also described.
    Type: Application
    Filed: December 5, 2007
    Publication date: October 23, 2008
    Applicant: VALTECH CARDIO, LTD.
    Inventors: AMIR GROSS, IFTAH BEINART, ELIAHU ELIACHAR, NIR LILACH, RAM GROSSFELD, DMITRY GOLOM, GIDEON MEYER-BRODNITZ, ARNON MOSAIUF
  • Publication number: 20080208332
    Abstract: Valve prostheses are disclosed that are adapted for secure and aligned placement relative to a heart annulus. The valve prostheses may be placed in a non-invasive manner, e.g., via trans-catheter techniques, and may be positioned/repositioned until proper alignment and positioning is achieved. The valve prosthesis may include a resilient ring, a plurality of leaflet membranes mounted with respect to the resilient ring, and a plurality of positioning elements movably mounted with respect to the flexible ring, each of the positioning elements defining a first tissue engaging region and a second tissue engaging region spaced from the first tissue engaging region.
    Type: Application
    Filed: October 10, 2007
    Publication date: August 28, 2008
    Applicants: ENDOVALVE, INC., THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: David G. Lamphere, Tuan Anh Nguyen, Howard C. Herrmann
  • Patent number: 7416530
    Abstract: There is disclosed a medical device adapted to be implanted in the heart of a patient and operable therein i) as a heart valve; or ii) to assist in the functioning of one of the patient's heart valves; or iii) to monitor the functioning of one of the patient's heart valves. The device includes one or more sensors for sensing a physiologically or clinically relevant parameter of a patient. A telemetric communication device telemetrically transmits data related to a parameter sensed by the sensor to a remote device.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: August 26, 2008
    Assignee: L & P 100 Limited
    Inventors: Nicholas McMahon Turner, Peter Alfred Payne, G. Alban Davies, Julie A. Davies, Simon John Patrick O'Riordan
  • Publication number: 20080188929
    Abstract: Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. In a first embodiment, an expandable pre-assembled heart valve includes a plastically-expandable annular base having plurality of upstanding commissure posts. A tubular flexible member including a prosthetic section and a fabric section is provided, with the prosthetic section being connected to the commissure posts and defining leaflets therebetween, and the fabric section being attached to the annular base. In a second embodiment, an expandable heart valve includes an annular tissue-engaging base and a subassembly having an elastic wireform and a plurality of leaflets connected thereto. The annular base and subassembly are separately stored and connected just prior to delivery to the host annulus. Preferably, the leaflet subassembly is stored in its relaxed configuration to avoid deformation of the leaflets. The expandable heart valves may be implanted using a balloon catheter.
    Type: Application
    Filed: April 8, 2008
    Publication date: August 7, 2008
    Inventor: Stefan Schreck
  • Publication number: 20080177382
    Abstract: Embodiments of a medical device and methods for percutaneously treating a heart valve. In one embodiment, the medical device has a first cardiac tissue fastener having a first lock, a second cardiac tissue fastener having a second lock, and a chord coupled to the first and second fasteners. Pulling the chord engages the first lock with the second lock.
    Type: Application
    Filed: February 22, 2008
    Publication date: July 24, 2008
    Inventors: Gregory Matthew Hyde, Mark Juravic, Stephanie A. Szobota, Brad David Bisson
  • Publication number: 20080140188
    Abstract: Devices, systems, and methods employ a heart implant structure that is sized and configured to be positioned in a left atrium above the plane of a native mitral heart valve annulus to affect mitral heart valve function. The implant structure includes a portion sized and configured to engage a wall of the left atrium above the plane of the native mitral valve annulus and to extend across the left atrium along a minor axis of the annulus.
    Type: Application
    Filed: October 31, 2007
    Publication date: June 12, 2008
    Inventors: David A. Rahdert, Timothy R. Machold, John A. Macoviak, Robert T. Chang
  • Publication number: 20080086204
    Abstract: An intra-annular mounting frame useful for, inter alia, restoring the geometry of a valve to achieve proper coaptation.
    Type: Application
    Filed: May 3, 2007
    Publication date: April 10, 2008
    Inventor: J. Scott Rankin
  • Publication number: 20080071369
    Abstract: Apparatus is provided including a prosthesis for implantation at a native semilunar valve of a native valve complex of a subject, the native valve complex having semilunar sinuses, the prosthesis including a valve prosthesis support, which includes a support structure including at least two engagement arms. Upon implantation of the prosthesis, each of the engagement arms is at least partially disposed within a respective one of the semilunar sinuses. A shape of at least one of the engagement arms is generally characterized by a function z?(r)>=0, where z is a height of any given point on the at least one engagement arm measured along a longitudinal axis of the prosthesis, and r is a distance from the longitudinal axis to the given point. Other embodiments are also described.
    Type: Application
    Filed: March 23, 2007
    Publication date: March 20, 2008
    Inventors: Yosi Tuval, Ido Kilemnik, Raphael Benary