Having Textured Outer Surface Patents (Class 623/23.5)
  • Publication number: 20080249632
    Abstract: A method of distributing a load to a cartilage defect repair plug is provided. A load is applied to a first articulation layer. The load is distributed to a second layer and the load is transferred in the normal direction to the first density of subchondral bone. The load is distributed to a third layer and the load is transferred in the normal direction to a second density of subchondral bone. The load is then distributed to a fourth layer and the load is transferred in the normal direction to a third density of subchondral bone.
    Type: Application
    Filed: February 26, 2007
    Publication date: October 9, 2008
    Applicant: Biomet Sports Medicine, Inc.
    Inventors: Kevin T. Stone, Karen Troxel
  • Publication number: 20080208351
    Abstract: A biocompatible material, wherein at least a part of a surface of the biocompatible material is characterized by a micro or nano-meter scale topographical structure comprising a plurality of features where the structure is selected to promote a predetermined cell function in vivo or ex vivo in cell or tissue culture.
    Type: Application
    Filed: April 25, 2006
    Publication date: August 28, 2008
    Applicant: Aarhus Universitet
    Inventors: Flemming Besenbacher, Mogens Ryttergard Duch, Morten Foss, Finn Skou Pedersen, Jeannette Hoffmann Frisch Justesen, Lars Klembt Andersen, Trine Elkjaer Larsen Crovato, Lotte Markert
  • Publication number: 20080125868
    Abstract: An implant and an implant member for attaching to living biological tissue of a human being or an animal. The implant has an outer surface comprising a first part and a second part which have different properties with regard to the biocompatibility of each part with biological tissue. The implant includes at least one surface portion comprising a ground surface making up the first part and one or several delimited regions making up said second part. A method for producing the implant, where a perforated masking unit is applied onto the implant, and a masking unit for the method.
    Type: Application
    Filed: December 12, 2005
    Publication date: May 29, 2008
    Inventors: Rickard Branemark, Peter Thomsen
  • Patent number: 7323013
    Abstract: A prosthetic femoral implant for use in a hip joint, as a ball and socket type joint, is disclosed. The implant includes a modular neck having a variety of adjustable positions to adjust the lateral offset and version angle of the femoral implant in relation to the femur. The implant further includes a broad, full collar for providing a compression force increasing the interdigitation between the interface of the bone, implant and cement. The implant also includes a stem having a depression having a roughened porous surface for resisting the increased torsional loads placed on the implant due to the increased lateral offset and version angle. The stem further comprises three distinct zones, each zone having its own roughened surface creating a tripartite differential porosity.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: January 29, 2008
    Assignee: Encore Medical Asset Corporation
    Inventors: Timothy McTighe, Ian Murray, Hugh U. Cameron
  • Patent number: 7258810
    Abstract: A textured surface and oxidation layer coating on a metallic material is accomplished through the chemical and/or electrochemical etching of the surface to modify the surface texture and an in-situ oxidation procedure. The surface is useful for the fabrication of prosthetic devices, particularly medical implants, due to the corrosion and wear resistance imparted by the oxidation layer and the ability to enhance grafting of the implant onto bone imparted by the surface texture.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: August 21, 2007
    Assignee: Smith & Nephew, Inc.
    Inventors: Gordon Hunter, Randy Fesmire, Harsh Gupta, Daniel Heuer
  • Publication number: 20070173949
    Abstract: A biocompatible bonding material is applied as an intermediary to attach prosthesis to boney tissue. The bonding material has the strength and rapid setting characteristics of PMMA cement, and is incorporated by the supporting bone as the boney ingrowth and osteogenic growth processes take place. In one embodiment, the bonding material is comprised of calcium phosphate polymer that provides immediate hardening and bonding, thereby locking the prosthesis to the bone. The biologic bond allows for bone in-growth over a period of weeks providing long term fixation. The immediate bonding can eliminate the early loosening that commonly occurred with uncemented joint replacements.
    Type: Application
    Filed: September 18, 2006
    Publication date: July 26, 2007
    Inventors: Lewis S. Sharps, Richard A. Balderston
  • Patent number: 7244275
    Abstract: The present invention is a specialized orthopedic implant having an exterior surface for engaging bone. The surface comprises arrayed projections having at least one forward facing facet directed at least in part toward the leading end of the implant and at least one rearward portion directed at least in part toward the opposite trailing end of the implant. Each of the forward facet and rearward portion has a length and a slope. The length of the forward facet is longer than the length of the rearward facet. The slope of the rearward facet is steeper than the slope of the forward facet. The surface projections also have opposed side facets directed generally toward the sides of the implant. The side facets are located between the forward facet and rearward facet and converge toward each other in a direction away from the base of the surface projections. The surface may also include projections having left and right forward side facets and a rearward facet.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: July 17, 2007
    Assignee: Warsaw Orthopedic, Inc.
    Inventor: Gary K. Michelson
  • Patent number: 7087540
    Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: August 8, 2006
    Assignee: curasan AG
    Inventors: Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz
  • Patent number: 7052518
    Abstract: An artificial bone comprising a calcium phosphate-based ceramic porous body having a plurality of pores which are three-dimensionally distributed throughout an entire region of the porous body including a surface thereof and have a diameter ranging from 0.01 ?m to 2000 ?m, and interconnecting portions which are formed between neighboring pores, interconnect a plurality of pores existing on a surface of the porous body.
    Type: Grant
    Filed: September 18, 2003
    Date of Patent: May 30, 2006
    Assignee: Olympus Corporation
    Inventors: Hiroyuki Irie, Hikaru Inoue
  • Patent number: 7018418
    Abstract: Textured surface having micro recesses such that the outer surface overhangs the micro recesses. Embodiments of the textured surface include sharp edges for promoting bone deposition and growth within the micro recesses, protrusions of varying depth from the surface that include overhangs, and micro recesses that are at least partially defined by complex ellipsoids.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: March 28, 2006
    Assignee: Tecomet, Inc.
    Inventors: Mark Amrich, Jonathan L. Rolfe, Joseph Buturlia, Robert F. Lynch
  • Patent number: 7014661
    Abstract: A transcutaneous prosthesis is disclosed comprising a first component (1) shaped for implantation into a bone (2), a second component (4) intended for location between the bone (2) and the skin, and a third component (5) intended for location exterior to the skin surface, having a low surface energy which deters bacterial adhesion. The second component (4) may carry an adhesion-promoting protein.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: March 21, 2006
    Assignee: University College London
    Inventors: Gordon Blunn, Justin Cobb, Allen Goodship, Paul Unwin
  • Patent number: 7012034
    Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: March 14, 2006
    Assignee: curasan AG
    Inventors: Helmut Heide, Joachim Pabst, Albrecht Dinkelaker, Olaf Pobantz
  • Patent number: 6840960
    Abstract: A porous implant system includes a gradient source adapted for transferring a gradient to an interface connected to an implant at a patient situs. The gradient source is controlled by a programmable controller. The implant is bonded to the patient by tissue ingrowth, which is facilitated by the gradient formed across the porous portion of the implant. A treatment method and includes the steps of providing a porous implant, connecting same to a gradient source through an interface, forming a gradient across the implant and controlling the operation of the gradient source according to a predetermined and preprogrammed treatment protocol.
    Type: Grant
    Filed: September 27, 2002
    Date of Patent: January 11, 2005
    Inventor: Stephen K. Bubb
  • Publication number: 20040267376
    Abstract: Disclosed herein is a ceramic member for a medical implant which exhibits improved binding with the bone without detracting from the excellent mechanical properties inherent to the ceramic material. The ceramic member for a medical implant has a surface layer having a roughened surface. When attention is paid to one type of crystal phase of the crystal phases of the ceramics constituting the surface layer, difference between the content in % by mass of this crystal phase of interest in the surface layer and the content in % by mass of this crystal phase of interest deep in the ceramic member is within 10%.
    Type: Application
    Filed: June 22, 2004
    Publication date: December 30, 2004
    Applicant: Kabushiki Kaisha Kobe Seiko Sho (Kobe Steel, Ltd)
    Inventors: Jun Suzuki, Takahiro Kudou, Tomiharu Matsushita
  • Publication number: 20040254668
    Abstract: A solid freeform fabrication method and composition for preparing a calcium phosphate-based macro-porous scaffold for tissue engineering applications.
    Type: Application
    Filed: June 16, 2003
    Publication date: December 16, 2004
    Inventors: Bor Z. Jang, Laixia Yang
  • Publication number: 20040243133
    Abstract: Various elements and alloys selected to achieve both biocompatibility and low melting point for use in infiltrating a porous matrix. The infiltrated porous matrix may be made of ceramic, metal, bioglass, or other suitable material. The infiltrated matrix may be used as a biomedical implant, such as for bone repair and regeneration. The matrix may be manufactured using solid free form fabrication techniques such as three-dimensional printing.
    Type: Application
    Filed: March 5, 2004
    Publication date: December 2, 2004
    Applicant: Therics, Inc.
    Inventor: Peter A. Materna
  • Publication number: 20040236430
    Abstract: The invention relates to a cement-free hip endoprosthesis for the femur (1), comprising a shaft (2) which can be inserted into the femur (1) and has a curvature, and comprising at least approximately parallel or concentric grooves (3) or ribs (4) along the shaft surface, the proximal end (5) of the shaft (2) being formed without a collar, and the groove base in the proximal region (6) running out in a shoulder-shape for at least a part of the groove (3b), resulting in a good seat in combination with a short design length.
    Type: Application
    Filed: June 14, 2004
    Publication date: November 25, 2004
    Inventors: Rudolf Koch, Henning Sturz
  • Patent number: 6802867
    Abstract: Disclosed is an orthopedic implant suitable for arthroplasty procedures. The orthopedic implant includes a first plate, a second plate, an axial support between the first plate and the second plate and one or more torsional supports connecting the first plate and the second plate. The axial support may be, for example, one or more flexible struts, such as cables, or a ball and socket joint. The torsional supports connect the first and second plates and may be, for example, curved around the axial support. The torsional supports may be integrally formed with the first and second plates as a single unitary device, by, for example, a Laser Engineered Net Shape (LENS) process.
    Type: Grant
    Filed: December 20, 2002
    Date of Patent: October 12, 2004
    Assignee: DePuy AcroMed, Inc.
    Inventors: Mark Manasas, Keith Oslakovic, Cornel Sultan, John Hamilton, Donald Ingber
  • Publication number: 20040199261
    Abstract: A method of forming a roughened, decontaminated surface on a metal article which includes the single or multiple blasting of the surface with a chilled iron grit of appropriate roughness structure followed by acid pickling to produce a contamination free surface of substantially Sq 5 to 10 microns.
    Type: Application
    Filed: February 20, 2004
    Publication date: October 7, 2004
    Applicant: Benoist Girard SAS
    Inventor: Eric Jones
  • Publication number: 20040199260
    Abstract: Prosthetic joints, components for prosthetic joints, superhard bearing and articulation surfaces, diamond bearing and articulation surfaces, substrate surface topographical features, materials for making joints, bearing and articulation surfaces, and methods for manufacturing and finishing the same, and related information are disclosed, including a prosthetic joint component having at least one sintered polycrystalline diamond compact articulation surface and substrate surface topographical features in said polycrystalline diamond compact.
    Type: Application
    Filed: January 9, 2004
    Publication date: October 7, 2004
    Inventors: Bill J. Pope, Jeffrey K. Taylor, Richard H. Dixon, Clayton F. Gardinier, Louis M. Pope, Dean C. Blackburn, Michael A. Vail, Kenneth M. Jensen
  • Patent number: 6800093
    Abstract: A spinal implant replaces excised tissue removed during spine surgery. This implant includes fasteners which firmly attach it to vertebrae adjacent to excised tissue so as to transmit tension and torsional loads to and from those vertebrae. The body of the implant has through cavities into which bone growth material is placed during surgery. The body of the implant also has a finite modulus of elasticity in compression so as to share compressive loads with emplaced bone growth material and with new bony growth facilitated by the emplaced material and the load sharing.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: October 5, 2004
    Assignee: Cortek, Inc.
    Inventors: James E. Nicholson, Scott G. Tromanhauser, Dale E. Whipple
  • Patent number: 6793678
    Abstract: An articulating motion disc having a core member that expands laterally in response to an axial load to mimic the shock absorbing function of a natural intervertebral disc.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: September 21, 2004
    Assignee: DePuy Acromed, Inc.
    Inventor: John Riley Hawkins
  • Publication number: 20040181286
    Abstract: The present invention is a specialized orthopedic implant having an exterior surface for engaging bone. The surface comprises arrayed projections having at least one forward facing facet directed at least in part toward the leading end of the implant and at least one rearward portion directed at least in part toward the opposite trailing end of the implant. Each of the forward facet and rearward portion has a length and a slope. The length of the forward facet is longer than the length of the rearward facet. The slope of the rearward facet is steeper than the slope of the forward facet. The surface projections also have opposed side facets directed generally toward the sides of the implant. The side facets are located between the forward facet and rearward facet and converge toward each other in a direction away from the base of the surface projections. The surface may also include projections having left and right forward side facets and a rearward facet.
    Type: Application
    Filed: March 25, 2004
    Publication date: September 16, 2004
    Inventor: Gary K. Michelson
  • Publication number: 20040167632
    Abstract: The invention provides a method of providing a metallic orthopaedic implant with a micron or nanometer-scale surface roughness to facilitate acceptance of tissue and bone growth or apposition after implantation while maintaining the structural integrity of the orthopaedic implant. The invention also provides a metallic orthopaedic implant comprising a metallic body and metallic elements adhered to a portion of the surface of the metallic body to define a three-dimensional porous surface geometry, wherein at least some of the metallic elements have a micron or nanometer-scale surface roughness.
    Type: Application
    Filed: February 24, 2003
    Publication date: August 26, 2004
    Applicant: DePuy Products, Inc.
    Inventors: Hai Bo Wen, Panjian Li, Todd Smith
  • Publication number: 20040162622
    Abstract: A cartilage plug, which is made from a biocompatible, artificial material, that is used to fill a void in natural cartilage that has been resected due to traumatic injury or chronic disease is disclosed. Alternatively, the plug may be relied upon to anchor a flowable polymer to subchondral bone. The plug is prefabricatable in any size, shape, and contour and may be utilized either singly or in a plurality to fill any size void for any application. The plug may be formed of a laminated structure to match the physiological requirements of the repair site. Additionally, ridges may be formed about the periphery of each plug to facilitate its anchoring to surrounding cartilage, bone and/or adjacent plugs.
    Type: Application
    Filed: September 30, 2003
    Publication date: August 19, 2004
    Applicant: ChondoSite, LLC
    Inventors: Timothy M. Simon, Harold M. Aberman, Douglas W. Jackson
  • Publication number: 20040148031
    Abstract: The surface of a device that is surgically implantable in living bone is prepared. The device is made of titanium with a native oxide layer on the surface. The method of preparation comprises the steps of removing the native oxide layer from the surface of the device and performing further treatment of the surface substantially in the absence of unreacted oxygen.
    Type: Application
    Filed: November 5, 2003
    Publication date: July 29, 2004
    Inventor: Keith D. Beaty
  • Publication number: 20040133275
    Abstract: A permanent non-resorbable implant allows surgical replacement of cartilage in articulating joints, using a hydrogel material (such as a synthetic polyacrylonitrile polymer) reinforced by a flexible fibrous matrix. Articulating hydrogel surface(s) are chemically treated to provide a negative electrical charge that emulates the negative charge of natural cartilage, and also can be treated with halogenating, cross-linking, or other chemical agents for greater strength. For meniscal-type implants, the reinforcing matrix can extend out from the peripheral rim of the hydrogel, to allow secure anchoring to soft tissue such as a joint capsule. For bone-anchored implants, a porous anchoring layer enables tissue ingrowth, and a non-planer perforated layer can provide a supportive interface between the hard anchoring material and the softer hydrogel material.
    Type: Application
    Filed: October 2, 2003
    Publication date: July 8, 2004
    Inventor: Kevin A. Mansmann
  • Patent number: 6726725
    Abstract: Orthopedic implants comprising components of zirconium or zirconium-based alloys having surfaces coated with oxidized zirconium contacting other surface-coated oxidized zirconium are disclosed. Such implants provide low friction, highly wear resistant coatings especially useful in artificial joints, such as hip joints, knee joints, elbows, etc., but also useful in non-articulating implant devices such as bone plates, bone screws, etc.
    Type: Grant
    Filed: July 24, 2001
    Date of Patent: April 27, 2004
    Assignee: Smith & Nephew, Inc.
    Inventors: Gordon Hunter, Ajit Mishra
  • Publication number: 20040064192
    Abstract: A porous implant system includes a gradient source adapted for transferring a gradient to an interface connected to an implant at a patient situs. The gradient source is controlled by a programmable controller. The implant is bonded to the patient by tissue ingrowth, which is facilitated by the gradient formed across the porous portion of the implant. A treatment method and includes the steps of providing a porous implant, connecting same to a gradient source through an interface, forming a gradient across the implant and controlling the operation of the gradient source according to a predetermined and preprogrammed treatment protocol.
    Type: Application
    Filed: September 27, 2002
    Publication date: April 1, 2004
    Inventor: Stephen K. Bubb
  • Publication number: 20040054417
    Abstract: A disposable articulated spacing device for the treatment of joints of the human body, particularly for temporarily replacing an explanted joint prosthesis, comprises at least one first member able to be secured to a first articulation end and at least one second member able to be secured to the other articulation end, both said members being pre-formed and made entirely of biological compatible and porous material suitable to be added with pharmaceutical and therapeutical products. The pre-formed members are reciprocally coupled in an articulated manner to maintain a suitable joint space and at least a partial articulation for the time necessary to perform the further implantation of a joint prosthesis. The biologically compatible and porous material is chosen among metals, metallic alloys, organo-metals, ceramics, glasses, plastics materials, bone cements and combinations thereof.
    Type: Application
    Filed: February 5, 2003
    Publication date: March 18, 2004
    Inventors: Renzo Soffiati, Claudio Castelli, Giovanni Faccioli
  • Publication number: 20040034433
    Abstract: A prosthetic component is configured to have intentional interruptions in an articulating face thereof. The intentional interruptions are configured to yield an optimum contact area or bearing surface, particularly with regard to low wear and greater lubricity through the application of lubrication and contact mechanics theory for the particular prosthetic component. Such optimization is applied to a wide range of prosthetic component sizes of the particular prosthetic component. The optimum range of percentage area of relief or interruptions, defined as a percentage of a baseline uninterrupted bearing surface area to be removed by the features of the interrupted bearing surface configuration is from 0.3% to 73.7% for hard-on-hard bearing components and from 5.7% to 83.2% for polyethylene-on-hard bearing components. The range for both hard-on-hard and polyethylene-on-hard implants translates to a relieved area ranging from 0.3% to 31.
    Type: Application
    Filed: August 18, 2003
    Publication date: February 19, 2004
    Inventors: Frank W. Chan, Jorge A. Ochoa
  • Publication number: 20040019385
    Abstract: Methods for producing porous tricalcium phosphate net-shaped material are provide. The methods involve preparing a reactant mixture comprising calcium oxide and phosphorus pentoxide in a mole percent ratio that allows the mixture to form tricalcium phosphate upon combustion thereof, forming this mixture into a desired final shape in a die with compression, and carrying out a combustion synthesis therewith. Net-shaped TCP materials of the combustion synthesis, comprising alpha tricalcium phosphate or mixtures of alpha and beta tricalcium phosphate, are optionally further treated to effect transition of the alpha phase to the beta phase. The net-shaped TCP materials can have a uniform or non-uniform porosity.
    Type: Application
    Filed: July 16, 2003
    Publication date: January 29, 2004
    Inventors: Reed A. Ayers, Steven J. Simske, John J. Moore, Martin Castillo, Guglielmo Gottoli
  • Publication number: 20040019132
    Abstract: The present invention is directed to methods and compositions for manufacturing a bone graft substitute. A powder compaction process is utilized to generate a shaped product comprised of a granulated bone material, such as demineralized bone matrix. In addition, a processing aid is utilized to facilitate compaction of the granulated bone material and for release of the product from the die.
    Type: Application
    Filed: July 17, 2003
    Publication date: January 29, 2004
    Inventors: Marc Long, Michael B. Cooper, Keith M. Kinnane, Trevor Allen, Jeffrey E. Schryver
  • Publication number: 20040006396
    Abstract: A transcutaneous implant constitutes proximal partially external section; a collar section, integrally dependent from the external section, the collar section having a microtextured surface constituting a microgeometric, repetitive surface pattern, in a form of multiplicity of alternating ridges and grooves, each having an established width in a range of about 2 to about 25 microns, and an established depth in a like range; an anchor-like distal section, integrally dependent from the collar section, for implantation into a bone segment to be stabilized during a medically advantageous period of time. The surface pattern defines a guide at tissue, cellular and molecular levels for a preferential promotion of rate, orientation and direction of growth of colonies of cells which are in contact with the pattern.
    Type: Application
    Filed: September 6, 2002
    Publication date: January 8, 2004
    Inventors: John L. Ricci, Harold Alexander
  • Patent number: 6660041
    Abstract: The invention relates to a hollow rasp for preparing a tubular bone in which a post-shaped endoprosthesis is inserted. A manipulating instrument can be proximally coupled to the rasp. The rasp comprises a metal grid network and a plurality of metal rasp elements. The metal rasp elements are studded at least at junctions of the metal grid network and are an integral part of a material forming the grid network.
    Type: Grant
    Filed: July 31, 2001
    Date of Patent: December 9, 2003
    Assignee: Eska Implants GmbH & Co.
    Inventor: Hans Grundei
  • Patent number: 6602293
    Abstract: An orthopedic implant comprising a thermoplastic polymer or a composite comprising, in one embodiment, polyetheretherketone reinforced with 10% by volume of glass fibers, with an elastic modulus approximating the elastic modulus of bone. A porous coating is formed on the implant surface by creating a roughness thereon, by coating the surface with hydroxyapatite or by embedding a biocompatible material such as titanium in the surface. A two piece embodiment of the implant is joined and locked together, after the opposite ends of each piece are inserted in the medullary canal, using an interlocking mechanism comprising a fluted protrusion on one piece and a corresponding fluted cavity in the other piece with the fluted portions being complementarily tapered.
    Type: Grant
    Filed: November 1, 1996
    Date of Patent: August 5, 2003
    Assignee: The Johns Hopkins University
    Inventors: Paul J. Biermann, Jack C. Roberts, Amy A. Corvelli
  • Patent number: 6599322
    Abstract: A surgical implant having a datum surface for engaging tissue. Embodiments of the surgical implant include a recess in an original datum surface having a sharp undercut ovoid configuration and a multiplicity of recesses that are interconnected.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: July 29, 2003
    Assignee: Tecomet, Inc.
    Inventors: Mark P. Amrich, Joseph Buturlia, Robert F. Lynch, Jonathan L. Rolfe
  • Publication number: 20030138473
    Abstract: Shaped, composite bodies are provided. One portion of the shaped bodies comprises an RPR-derived porous inorganic material, preferably a calcium phosphate. Another portion of the composite bodies is a different solid material, preferably metal, glass, ceramic or polymeric. The shaped bodies are especially suitable for orthopaedic and other surgical use.
    Type: Application
    Filed: June 7, 2002
    Publication date: July 24, 2003
    Inventors: Antony Koblish, Ronald Sapieszko, David Dychala, Erik Erbe
  • Publication number: 20030135282
    Abstract: A section of the implant is treated successively and separately with three different acids—hydrofluoric, sulphuric and hydrochloric acid—to create evenly distributed peaks on the surface and sufficient surface area. Plasma rich in growth factors is then applied to said surface.
    Type: Application
    Filed: February 14, 2003
    Publication date: July 17, 2003
    Inventor: Eduardo Aldecoa Anitua
  • Publication number: 20030130742
    Abstract: An artificial joint assembly that contains a first member of bone and, attached to the first member, a second member that contains shape memory material; the second member is located, at least in part, within the first member.
    Type: Application
    Filed: December 13, 2002
    Publication date: July 10, 2003
    Inventors: Patrick R. Connelly, David L. Gushue
  • Publication number: 20030120348
    Abstract: An artificial bone graft implant for use as a replacement for living bone material in surgical procedures requiring the use of bone graft material includes a body formed of a microporous material and configured to be implanted into a prepared site in a patient's bone tissue. The body has a center portion, an outer portion and a pair of opposed outer surfaces defining the body. The body has a small average pore size in the center portion that gradually changes to larger average pore size in the outer portion. The pore size of the center portion of the implant allows for a load bearing capacity similar to natural bone and the pore size of the outer portion of the implant allows for the ingrowth of bone tissue.
    Type: Application
    Filed: January 29, 2003
    Publication date: June 26, 2003
    Inventors: Robert Brosnahan, Laura C. Small, Julie A. Bearcroft
  • Publication number: 20030108659
    Abstract: A process for creating surface microporosity on a titanium (or other metal) medical device includes creating a surface oxide layer on the device; placing the device, which is connected to a negative terminal of an electrical power supply, into a calcium chloride bath; connecting the positive terminal of the power supply to an anode immersed in or containing calcium chloride thereby forming an electrolytic cell; passing current through the cell; removing the device from the bath; and cooling and rinsing the device to remove any surface salt. If necessary, the device is etched to remove metal oxide which may have formed during the cooling process. The resulting device has a microporous surface structure. Alternatively, only a designated surface portion of a medical device is made microporous, either by applying a non-oxidizing mask, removing a portion of the oxide layer, or subtracting a portion of a microporous surface.
    Type: Application
    Filed: January 14, 2003
    Publication date: June 12, 2003
    Applicant: Syntheon, LLC
    Inventors: Thomas O. Bales, Scott L. Jahrmarkt
  • Patent number: 6558422
    Abstract: In one aspect the present invention provides indented structures that each include (a) a body defining a plurality of indentations, substantially all of the plurality of indentations including a surface layer including a biologically active substance; and (b) a body surface, wherein each of the plurality of indentations opens onto the body surface through a plurality of openings, and wherein the biologically active substance is not substantially present on the body surface. Examples of structures of the present invention include medical devices, such as medical devices that are completely or partially implantable into a living body. The surface layer of the indentations (or at least some of the indentations) of the medical devices of the invention may include biologically active molecules, such as proteins, that promote the growth of cells into and/or within the indentations, thereby promoting the acceptance of the implanted device by the living body.
    Type: Grant
    Filed: March 22, 2000
    Date of Patent: May 6, 2003
    Assignee: University of Washington
    Inventors: Aaron B. Baker, Joan E. Sanders
  • Patent number: 6554867
    Abstract: The intraosseous implant intended to be fitted in a bone is provided on the surface with a specific roughness, the implant surface having depressions (1) with a depth (c) of about 20 &mgr;m to about 60 &mgr;m. At the bottom of the depressions (1) there are base faces (2), and between the depressions (1) there are plateau faces (3). Base faces (2) and plateau faces (3) have a horizontal extent (a, b) of about 10 &mgr;m to about 20 &mgr;m. These depressions (1) are ideally as smooth as possible, i.e. they have no surface roughness below the cellular dimension. Obliquely ascending side faces (4) extend from the base faces (2) to the plateau faces (3), and the angle of inclination (&agr;) between the horizontal and the side faces (4) is about 30° maximum. Below the upper neck portion, the implant has a self-tapping thread, and the neck portion of the implant is provided with a porcelain-like coating. The surface energy and surface tension of the implant are kept as low as possible.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: April 29, 2003
    Assignee: Lipat Consulting AG
    Inventor: Ulrich Joos
  • Publication number: 20030074081
    Abstract: The present invention is generally directed to a method for the production of tissue implants and prosthetics, including but not limited to orthopedic implants and prosthetics which have a controlled and directional gradient of porosity moving through all or one or more portions of the implant, as well as the implants produced by such a method. The non-uniform porosity gradient may be linear or more complex, and is preferably produced to have a continuous gradient within the desired regions. The desired effect is to create an implant which more closely mimics the natural structure of bone, and which improves the quality of the bone growth that occurs within the implant.
    Type: Application
    Filed: July 19, 2002
    Publication date: April 17, 2003
    Inventor: Reed A. Ayers
  • Patent number: 6547564
    Abstract: Implant (10) having a shaft which is adapted in use to be embedded in bone tissue and which has an outer surface provided with a circumferentially-oriented roughness. The circumferentially-oriented roughness has first and second axial sections (19, 21) with each section comprising a series of circumferentially-oriented peaks which have a crest and which are axially spaced apart by troughs. The axial spacing (d) between the crests of adjacent peaks in the first axial section (19) is less than the axial spacing (3d) between the crests of adjacent peaks in the second axial section (21). Although the axial spacing between the crests of adjacent peaks in the first and second axial sections of circumferentially-oriented roughness differs, the first and second axial sections of circumferentially-oriented roughness are adapted in use to provide the same or substantially the same pitch.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: April 15, 2003
    Assignee: Astra Aktiebolag
    Inventor: Stig Hansson
  • Publication number: 20030055511
    Abstract: A shaped particle for use in an array of interlocking particles to repair, replace, improve or augment a bone deficiency is provided. The particle is comprised of bone material and, in a preferred embodiment, has six extremities, and the interstitial spaces between the extremities of one particle accept the extremities of an adjacent particle in an array. In a preferred embodiment, the bone material is demineralized bone material. In some embodiments, the particle is suspended in a material that facilitates application of the particle to bone, and the material may contain biological factors that augment bone growth or prevent infection.
    Type: Application
    Filed: March 15, 2002
    Publication date: March 20, 2003
    Inventors: Jeffrey E. Schryver, Michael B. Cooper, Keith M. Kinnane, Marc Long, Trevor Allen, Ed Margerrison, Robert Morgan, Julie A. Bearcroft, Andrew Harrison, William B. Kaiser
  • Patent number: 6520996
    Abstract: Disclosed is an orthopedic implant suitable for arthroplasty procedures. The orthopedic implant includes a first plate, a second plate, an axial support between the first plate and the second plate and one or more torsional supports connecting the first plate and the second plate. The axial support may be, for example, one or more flexible struts, such as cables, or a ball and socket joint. The torsional supports connect the first and second plates and may be, for example, curved around the axial support. The torsional supports may be integrally formed with the first and second plates as a single unitary device, by, for example, a Laser Engineered Net Shape (LENS) process.
    Type: Grant
    Filed: June 5, 2000
    Date of Patent: February 18, 2003
    Assignee: DePuy AcroMed, Incorporated
    Inventors: Mark Manasas, Keith Oslakovic, Cornel Sultan, John Hamilton, Donald Ingber
  • Patent number: 6511509
    Abstract: The present invention is directed to a textured bone allograft for implantation in a patient, having one or more textured bone surfaces, and methods of making and using the textured bone graft. The textured surface preferably includes a plurality of closely spaced discrete, continuous, or a combination thereof, protrusions. The textured bone allograft is useful for repairing bone defects caused by congenital anomaly, disease, or trauma, in a patient, for example, for restoring vertical support of the anterior column. Implantation of the textured bone allograft results in improved graft stability and osteoinductivity, without a decrease in mechanical strength. The textured bone allograft does not shift, extrude or rotate, after implantation.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: January 28, 2003
    Assignee: LifeNet
    Inventors: Louis Ford, Lloyd Wolfinbarger, Jr., Jon C. Serbousek, Laine Mashburn, Jr.
  • Publication number: 20030009224
    Abstract: An artificial disc (10) to replace a damaged spinal disc in a spinal column (16) includes a resilient core (60) having an upper surface (62) and a lower surface (64). An upper retaining member (20) has an outer surface (22) engageable with a first vertebra (12) of the spinal column (16) and an inner surface (24) affixed to the upper surface (62) of the resilient core (60). A lower retaining member (40) has an outer surface (42) engageable with a second vertebra (14) of the spinal column (16) and an inner surface (44) affixed to the lower surface (64) of the resilient core (60). One of the upper and lower retaining members (20, 40) has an opening (30, 50) extending through the outer and inner surfaces into which the resilient core (60) deflects upon relative movement of the upper and lower retaining members (20, 40).
    Type: Application
    Filed: July 3, 2001
    Publication date: January 9, 2003
    Applicant: AxioMed Inc.
    Inventor: James Michael Kuras