Abstract: The present invention provides an accommodative intraocular lens (AIOL) system and method for improving accommodation with an intraocular lens. The method involves insertion into the capsular bag of a flexible optic holder comprising a plurality of haptics configured to allow the capsular bag to be sectioned at regular intervals following fusion of the capsular bag. The haptics of the optic holder are designed to allow maximum fusion of the anterior and posterior leaves of the capsular bag following placement of the optic holder in the capsular bag. Following introduction of the optic holder into the capsular bag, the natural or assisted process of fibrosis/fusion of the capsular bag occurs, thereby sealing and securely capturing the haptics within the capsular bag.

Abstract: A plate haptic for an intraocular lens. The plate haptic has a haptic body that is substantially rigid in a longitudinal direction and substantially flexible in a transverse direction. A chassis is integral to the haptic body. The chassis causes the haptic body to be substantially more rigid in a longitudinal direction than in a transverse direction.

Abstract: Presented is an accommodating intraocular lens (AIOL). The AIOL includes an optic and at least one haptic plate coupled to the optic by at least one connector, the connector being less rigid than the haptic plate, the at least one haptic plate surrounding the optic, and the optic and haptic plate having a combined surface area between 80 mm2 and 100 mm2. The at least one haptic plate may form a continuous 360-degree boundary around the optic. The at least one haptic plate has a width in a radial dimension of 1.0-3.5 mm across its entire angular extent.

Abstract: An accommodating intraocular lens (AIOL) includes an optic adapted to produce a trapezoidal phase shift and a plurality of haptics. Each haptic extends from a haptic-optic junction to at least one transverse arm contacting a capsular bag of the eye, and each haptic has sufficient length and rigidity to stretch a capsular bag of the eye to contact ciliary muscles of the eye. The haptic-optic junctions vault the optic forward relative to the haptics and compression of the haptics by the ciliary muscles moves the anterior optic forward. A combined accommodative power produced by the motion of the anterior optic and the trapezoidal phase shift is at least 0.5 Diopters.

Abstract: An intraocular lens is disclosed with an optic that changes shape in response to forces exerted by the zonules of the eye. A haptic with an inner and outer ring couples the optic to the capsular bag of the eye. The haptic stresses the optic when the intraocular lens is in a natural state such that the internal stress is present throughout the accommodation range in order to prevent ripples and/or waves in the optic.

Abstract: The accommodative intraocular lens 1 include an optical section 10 of a lens, and a lens supporting section 20 provided at the peripheral portion of the optical section 10. The lens supporting section 20 includes one end portion 201 connected to the peripheral portion of the optical section 10 via the connecting portion 50 in a movable manner, and the other end portion 202 to be engaged with the equator Se of the lens capsule S. The one end portion 201 and the other end portion 202 are positioned on opposite sides with respect to the center O of the optical section 10, and are formed in a manner as to extend on radially outward side in a loop shape surrounding the periphery of the optical section 10 from one end portion 201 to the other end portion 202.

Abstract: A deformable accommodating intraocular lens (IOL) is disclosed, where the IOL comprises a diffractive kinoform-like grating pattern on one or both of the anterior or posterior surfaces of the deformable IOL. The capsular bag of the eye exerts a distorting force on the IOL, changing its power and allowing for accommodation. The focal length variation obtained by the change in curvature of the refractive surface of the IOL is enhanced by the kinoform-like diffractive grating pattern in combination with the traditional refractive surface. The focal length variation obtained by stretching and shrinking of the diffractive pattern adds considerable power variation independent of the refractive index of the material used to make the IOL.

Abstract: For easy handling at placement of intra ocular lenses (IOLs) for cataract operations, these are equipped with helical haptics of memory materials circumferring the lens. Said haptics adhere to the rim of the lens as long as being cooled down to constriction temperature. On regaining body temperature the haptics expand and fit into the ridges of the eye's capsule sack. Accommodation then is achieved with constriction of the capsule sack by pressure transfer to the rim of the lens to form its shape, in multiplying it with some protrusion towards the pupil.

Abstract: An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: The invention relates to a intraocular lens system having a flexible anterior lens accommodation material behind the lens. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material. The anterior lens is flexible such that the curvature of the lens changes during accommodation. The anterior lens may be used alone or in combination with a posterior lens.

Abstract: An accommodating intraocular lens designed to provide a space in front of the lens optic, to allow it to move forward with accommodation, by stretching its connections to opposing plate haptics, to provide the patient with seamless vision from distance to near. The lens is designed to separate and prevent fibrosis of the anterior capsular rim with the posterior capsule where it surrounds the optic.

Abstract: An accommodating intraocular lens has a lens optic that is coupled to at least one haptic and is anteriorly biased with respect thereto.

Abstract: A vision correction arrangement is described in which a lens system having variable optical power varies in dependence on the orientation of the user's eye. The vision correction arrangement may be embodied as an intraocular lens implant, or an extraocular device such as spectacles. The intraocular lens implant comprises a fixed lens element (11) and a movable lens (12) element sensitive to the orientation of the eye, so that the optical power of the intraocular lens implant is increased when the user looks downward, and returns to a reduced optical power condition when the user's eye returns to a horizontal gaze. The fixed lens element may have a convex rear surface and a concave front surface, and the second lens element may be pivotally mounted in front of the first lens element, so that downward inclination of the eye causes the second lens element to swing away from the fixed lens element.

Abstract: An adjustable annuloplasty ring includes a body in the form of an endless loop having an internal lumen therethrough, an adjustment suture extending through at least a portion of the internal lumen, a first portion of the suture exiting the lumen through a first opening in the body and a second portion of the suture exiting the lumen through a second opening in the body, and a first adjustment marker on the first portion of the suture outside of the body. The suture may be adapted to reduce the length of the body around the loop when tightened.

Abstract: Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.

Abstract: A haptics system for retaining an accommodating intraocular lens (AIOL) in a human eye has an anterior surface and a posterior surface, and at least one shape memory optical element resiliently elastically deformable between a natural shape with a first Diopter strength and a deformed shape with a second Diopter strength different than the first Diopter strength whereby the AIOL has a continuously variable Diopter strength between a minimum Diopter strength for distance vision purposes and a maximum Diopter strength for near vision purposes.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The haptic includes a plurality of arms coupled to a compressible inner structure. The compressible inner structure of the haptic is configured to exert a compressive force on the optic in response to an ocular force to provide accommodation. The compressible inner structure can include a plurality of arcuate segments that join to form a ring in the fully compressed state or a sinusoidal ring having a varying radial dimension.

Abstract: An intraocular lens comprises an optic and at least two haptics, each of which comprises a step feature that protrudes from a posterior surface of the haptic to prevent posterior capsular opacification.

Abstract: An accommodating intraocular lens (AIOL) for implantation in a human eye includes a housing including an anterior member with a leading surface, a posterior member with a trailing surface, a leading shape memory optical element adjacent the anterior member and resiliently elastically deformable between a non-compressed shape in a non-compressed state of the AIOL and a compressed shape in a compressed state of the AIOL, and a trailing shape memory optical element adjacent the posterior member and elastically deformable between a non-compressed shape in the AIOL's non-compressed state and a compressed shape in the AIOL's compressed state for selectively bulging into the leading shape memory optical element on application of a compression force the said longitudinal axis against the trailing surface from a posterior direction for modifying the shape of the leading shape memory optical element with respect to its non-compressed shape in the AIOL' s the non-compressed state.

Abstract: Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.

Abstract: A method for prevention of migration of epithelial cells in a capsular bag of an eye of a mammal is provided. The method comprises removing the natural lens of the eye from the capsular bag; introducing an object with at least one sharp edge into the capsular bag, in such a way that said sharp edge contacts the inside of the capsular bag to form a barrier preventing migration of epithelial cells across said barrier; and injecting a lens-forming composition into the capsular bag.

Abstract: An ophthalmic lens is disclosed, one embodiment comprising an optic having an anterior surface and a posterior surface disposed about an optical axis, wherein at least one of the surfaces has a profile characterized by superposition of a base profile and an auxiliary profile, the auxiliary profile comprising a continuous pattern of surface deviations from the base profile. The auxiliary profile is a sinusoidal profile and can be amplitude modulated, frequency modulated or both amplitude and frequency modulated. The ophthalmic lens can be an IOL.

Abstract: An intraocular lens in which deterioration in contrast is suppressed even when the optical axis of the intraocular lens is decentred from the optical axis of the eyeball when the intraocular lens is inserted into the eye while the advantage of a conventional aberration reduction type intraocular lens that the image is seen clearly is sustained by employing such a power distribution as respectively having at least one positive power deviation region (E1) having a power larger than that represented by the reference power distribution and at least one negative power deviation region (E2) having a power smaller than that represented by the reference power distribution in the central region of the intraocular lens assuming that a power distribution being set to cancel the spherical aberration of cornea when the intraocular lens is inserted into the eye is the reference power distribution.

Abstract: An accommodative intraocular lens having a soft deformable resilient inner lens portion or core with an exposed anterior inner optic surface and exposed posterior optic surface, the surfaces responsively becoming simultaneously optically steeper and moving axially away from each other. The exposed anterior and posterior surfaces of the inner lens portions may be spherically shaped or aspherically shaped and the shape of the outer lens portion may be spherically or aspherically shaped.

Abstract: An improved intraocular lens, for example, an accommodating intraocular lens including a lens optic, the lens optic including a ring-shaped lens optic portion and/or a light window.

Abstract: A presbyopia correcting intraocular lens implant for implanting in a human eye includes an implant body having a central lens enclosure and at least one stability tab extending therefrom. At least one ciliary body sensor senses movement of the eye's ciliary body. An electronic module is embedded in the implant body and includes a microprocessor communicative with the ciliary body sensor. A dynamic lens assembly is housed in the central lens enclosure and has a dynamic range of continuous accommodation. The lens implant also includes a renewable intraocular power supply.

Abstract: An intraocular lens (IOL) having a posterior prolate aspheric surface structured to bend or flex in response to force applied to such surface due to flexing of ciliary body muscle. The flexible and bendable haptic portions of the IOL, integrated with the central optical portion along its perimeter, as sized to have the distal sides of the haptic portions installed in the capsular membrane of a natural lens of an eye or in a space between the root of the iris and ciliary muscle. The optical power of the IOL is gradually modifiable due to change of curvature of the posterior prolate aspheric surface within the eye.

Abstract: Ophthalmic lenses providing an extended depth of focus include anterior and posterior faces, wherein at least part of the anterior or posterior face has a curvature based upon the summation of a cubic and/or pentic phase profile, and methods relating to same. The ophthalmic lens may be a contact lens, an intraocular lens (IOL), or other corrective lens.

Abstract: An intraocular lens adapted to be implanted inside a capsular bag, comprising a peripheral portion comprising an anterior annular portion adapted to engage an anterior capsule portion, the anterior annular portion defining an anterior opening through which an optical axis passes, a posterior annular portion adapted to engage a posterior capsule portion, the anterior and posterior annular portions being adapted to keep the capsular bag open after implantation, and an optic portion disposed within the anterior opening and secured to and radially inward relative to the peripheral portion.

Abstract: An intraocular lens for providing accommodative vision includes an adjustable optic and a haptic that is operably coupled to the optic. The adjustable optic comprises a central zone and an annular zone surrounding the central zone. The optic may also comprise additional annular zones. The haptic comprises a transparent portion protruding into the adjustable optic. The intraocular lens has a disaccommodative configuration in which the central zone has a base optical power and an accommodative configuration in which the central zone has an add optical power that is at least about 1 Diopter greater than the base optical power. The central zone and the annular zone have different optical powers when the adjustable intraocular lens is in the accommodative configuration and/or when the adjustable intraocular lens is in the disaccommodative configuration.

Abstract: The invention relates to a device (1) for the vision correction of an eye (6), comprising: a converter (3, 3A, 3B, 5A, 5B) which can generate an electrical and/or magnetic and/or electromagnetic signal in response to the mechanical energy generated by a movement of the eye; and a soft lens (2) intended to be aligned with the eye. The converter is positioned in relation to the lens such that the electrical and/or magnetic and/or electromagnetic signal generated during the movement of the eye causes the optical properties of the lens to change. The invention is characterised in that the lens (2) includes a polymer material (7) containing a material (4) having a refractive index that can vary under the action of the electrical and/or magnetic and/or electromagnetic signal generated during a movement of the eye.

Abstract: An intraocular system is presented that may include an electro-active element having multiple independently controllable zones or pixels, and a controller capable of being remotely programmed. The system or element may be flexible, such that it can be folded for insertion into the eye. The system may include various energy storage and charging mechanisms to provide power to the lens and/or the controller.

Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

Abstract: An accommodative intraocular lens is described that provides monofocal vision at multiple pre-defined focal points during accommodation. The intraocular lens includes a lens element having a series of stacked optics that can be formed utilizing multiple different materials, each of which can have a different stiffness. In an implanted, disaccommodated state, the lens element can have a pre-defined curvature to thus define a first or base focal point of the intraocular lens. Upon accommodation of the patient's eye, the optics can be compressed and/or deformed at differing intervals so as to provide the intraocular lens with three or more distinct focal points. As an alternative, the lens element can include optics formed with multiple sets of haptic elements having varying haptic stiffnesses to vary compression of the optics in order to provide the intraocular lens with multiple focal points.

Abstract: An intraocular lens comprises an optic and at least two haptics. Each haptic is offset in an anterior direction from a central optic plane of the optic. The offset allows for predictable posterior vaulting upon implantation.

Abstract: An accommodative intraocular lens (IOL) system is disclosed for insertion into an eye to provide accommodative vision, the system including a deformable air chamber filled with a transparent, low refractive index medium disposed between the first and second optics; and at least one haptic connected to the air chamber and configured to facilitate a change in the curvature of at least one surface of the chamber, such that when the lens system is positioned in an eye, cilliary muscle movements can alter the curvature of the air chamber and vary the overall lens power of the system.

Abstract: An electro-active ophthalmic lens includes an electromyography sensor, a processor, and an electro-active optical element. The electromyography sensor is configured to detect an electric field in a ciliary muscle of the eye that is proportional to a force exerted by the ciliary muscle and to generate a sensor signal indicative of the electric field. The processor is operable to receive the signal from the electromyography sensor and to determine, based on the sensor signal, an adjustment to optical power for an electro-active optical element and to generate a control signal for the electro-active optical element. The electro-active optical element is operable to receive the control signal and to change an optical power of the electro-active optical element in response to the control signal.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: An accommodating intraocular lens has a lens optic that is coupled to at least one haptic and is anteriorly biased with respect thereto.

Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

Abstract: An accommodative lens assembly includes a lens body defining an optic lens, a haptic system, and a wing. The lens body is formed and implanted into an eye in a disaccommodative configuration. The haptic system includes one or more haptics that support the optic lens and transmits forces from an anatomical structure such as a ciliary body of the eye, causing the optic lens to deform into an accommodative configuration. In order to stabilize the optic lens so that the optic lens is not displaced from its implantation site, the wing anchors the optic lens within an anterior capsulorhexis of the capsular bag such that the transmitted forces that deform the optic lens during accommodation do not also displace the optic lens from its implanted position. When implanted, the optic lens is anterior to the capsular bag.

Abstract: An implantable ophthalmic device connectable to an implantable accommodating lens includes a dual-chamber sensor cell having a first and second plate where the second plate is disposed opposite the first plate. A first chamber with a first flexible membrane is disposed on an inner side of the first plate. A second chamber with a second flexible membrane is disposed on an inner side of the second plate. A space resides between the first and second chambers configured to receive a scleral spur of a ciliary muscle of a patient's eye. A connecting element is attached at a first end to the dual-chamber sensor cell. The connecting element includes a first and second channel disposed along a length of the connecting element and in communication with the first and second chamber of the dual-chamber sensor cell, respectively. The second end of the connecting element is connectable to the implantable accommodating lens.

Abstract: An accommodating intraocular lens comprising a lens optic coupled to at least one haptic and at least one deformable connecting bar positioned between the lens optic and the at least one haptic such that the connecting bar facilitates accommodation by deforming in response to a vitreous pressure change.

Abstract: An accommodating intraocular lens comprising a lens optic coupled to at least one haptic and a torsion bar positioned between the lens optic and the at least one haptic such that the torsion bar facilitates accommodation by deforming in response to a vitreous pressure change.

Abstract: Described herein are intraocular lenses and methods of implantation. In one aspect, the lens includes a shape changing optical element; a force translation element having a first end region coupled to the optical element and a second end region extending towards a ciliary structure, and an attachment portion coupled to the second end region of the force translation element and configured to contact the ciliary structure. The force translation element is configured to functionally transmit movements of the ciliary structure into a force exerted upon the optical element to effect an accommodating and a disaccommodating change of the optical element.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: An accommodating intraocular lens includes an adjustable optic, wherein the optic is capable of being moved between an accommodated state and an unaccommodated state. The optic includes an anterior portion, a posterior portion, and a sidewall between the anterior portion and the posterior portion. The lens further includes a ring disposed about the optic sidewall and a haptic coupled to the ring. The haptic is capable of being coupled to a patient's capsular bag. A method for implanting an accommodating intraocular lens is also provided.

Abstract: An intraocular lens in which deterioration in contrast is suppressed even when the optical axis of the intraocular lens is decentered from the optical axis of the eyeball when the intraocular lens is inserted into the eye while the advantage of a conventional aberration reduction type intraocular lens that the image is seen clearly is sustained by employing such a power distribution as respectively having at least one positive power deviation region (E1) having a power larger than that represented by the reference power distribution and at least one negative power deviation region (E2) having a power smaller than that represented by the reference power distribution in the central region of the intraocular lens assuming that a power distribution being set to cancel the spherical aberration of cornea when the intraocular lens is inserted into the eye is the reference power distribution.