Abstract: Intraocular lenses with high contrast haptics, materials and methods for making optical blanks and lenses, and methods of use are disclosed and claimed. Such lenses may provide easily recognizable visual cues that may be used to detect and correct misorientation of lenses prior to and during use.

Abstract: An intraocular lens is disclosed, with an adjustable optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The haptic may include a cap on the anterior and/or posterior surfaces of the lens. The lens may include a force transfer member, such as a hinge, that couples forces from the haptic to the cap, so that a radial force on the haptic changes the curvature of the cap. The haptic and optic may be refractive index-matched. The cap may be made of the haptic material, which is stiffer than the optic material, and can influence the deformation of the lens during accommodation. A cap on the anterior surface may produce an axial movement of the lens in an anterior direction during accommodation. The cap may also protect the surfaces of the optic during handling and installation.

Abstract: The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.

Abstract: A closed capsular tension ring, with a coil having at least one winding turn 6, wherein the winding turn 6 is disposed in the capsular tension ring 1. The closed capsular tension ring according to the invention has the advantage that it may be used without limitation to a particular artificial lens or to a particular shape of artificial lens.

Abstract: Visual aids and associated methods for improving the eye sight of low vision patients are provided. Generally, the devices of the present disclosure address the needs of age-related macular degeneration (AMD) and other low vision patients by providing a magnified retinal image while keeping a large visual field of view. Further, the devices of the present disclosure allow direction of the magnified retinal image away from damaged portions of the retina and towards healthy, or at least healthier, portions of the retina. The devices of the present disclosure are also configured for implantation within the eye using minimally invasive surgical procedures. Methods of utilizing the devices of the present disclosure, including surgical procedures, are also provided.

Abstract: An accommodating intraocular lens (AIOL) construction having optics (2) and haptic (1) connected with the optics for positioning the optics within the eye, wherein the introcular lens construction is made of a single material having spatially-distributed different elasto-mechanical properties, and the elasto-mechanical properties of the haptic differ from the elasto-mechanical properties of the optics. The haptic and the optics made from the same polymer material, i.e., having the same molecular constituency. The optical power of the lens construction can change along with change in the shape of the haptic and intraocular lens construction. The haptic is shaped such that compression along the circumference of the haptic increases the optical strength of the optics.

Abstract: An intraocular lens comprising: (a) monomeric units derived from at least one cationically polymerizable branched alkene monomer; (b) monomeric units derived from at least one cationically polymerizable monomer having a pendant benzocyclobutene group; and (c) a UV-absorbing benzotriazole component having the formula I.

Abstract: An intraocular lens for providing vision to an animal or human subject has anterior and posterior sides. The lens includes an optic body, one or more haptics, and one or more marks. Each mark has four or more features disposed along an imaginary line when viewed from the anterior side and/or the posterior side. The mark(s) may be used as an aid in angularly aligning the lens during use.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: Intraocular lens (1, 101) with an optic part (2) and a haptic part (3, 103), characterized in that it includes, at each transition between the optic part (2) and the haptic part (3, 103), two notches (7a, 8a, 14, 15, 122, 123), the two notches (7a, 8a, 14, 15, 122, 123) being arranged respectively on either side of the transition, each notch (7a, 8a, 14, 15, 122, 123) extending along the edge of the haptic part (3, 103) and impinging on the periphery of the optic part (2).

Abstract: Accommodating intraocular lens (AIOL) capsules having a continuously variable Diopter strength between a first Diopter strength in a non-compressed state and a second Diopter strength different than its first Diopter strength in a compressed state. The AIOL capsules include an anterior capsule plate, a posterior capsule plate, and a capsule ring for bounding a hermetic cavity filled with a capsule filling. The anterior capsule plate is intended to anteriorly bulge along the human eye's visual axis on application of an axial compression force against the posterior capsule plate from a posterior direction.

Abstract: Systems and methods for designing and implanting a customized intra-ocular lens (IOL) is disclosed. In one embodiment, a system includes an eye analysis module that analyzes a patient's eye and generates biometric information relating to the eye. The system also includes eye modeling and optimization modules to generate an optimized IOL model based upon the biometric information and other inputted parameters representative of patient preferences. The system further includes a manufacturing module configured manufacture the customized IOL based on the optimized IOL model. In addition, the system can include an intra-operative real time analyzer configured to measure and display topography and aberrometry information related to a patient's eye for assisting in proper implantation of the IOL.

Abstract: A method of anchoring an accommodating intraocular lens assembly in the posterior chamber of an eye whereby the lens assembly includes an optical axis that corresponds with the visual axis of a human eye. The posterior chamber includes a ciliary sulcus and a capsular unit with a collapsed natural lens capsule located therein. The assembly includes a substantially rigid haptics element having first and second haptic portions, which, when anchored, define a plane that intersects the visual axis of the eye. The haptics element secures the accommodating lens assembly within the posterior chamber outside the collapsed natural lens capsule and allows light to be transmitted therethrough at least in a region around said optical axis. A lens structure includes at least a resilient lens body located at least partially along the visual axis when the lens assembly is anchored in the posterior chamber of the eye.

Abstract: An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

Abstract: An IOL having a depressed inner optic area and a thickened or raised peripheral outer lip or rim integrally formed with the optic. Such a design reduces the mass of the IOL, making the lens easier to insert in a very small incision, without damaging the optic or compromising the stability of the IOL.

Abstract: A multi-component intraocular lens implanted in an optical system of a human eye, includes one or more removable components. One component acts as a base lens and another component acts as the front lens. A front lens formed from two integral optical portions may be milled with tabs to establish an axial orientation of the front lens. The front lens may have a different diameter than the base lens. The base lens may have sharp or angled edges and the front lens may have rounded edges. Non-optical portions of the intraocular lens system may be manufactured from a material that is capable of releasing a pharmacological agent. A flange may be fused with the base lens to allow the front lens to engage with the base lens.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The optic is disposed about an optical axis and includes an anterior surface and a posterior surface defining a clear aperture of the optic. The haptic is at least partially disposed inside the optic and includes an inner structure, an outer structure, and a plurality of arms disposed between and connecting the inner structure and the outer structure. The inner structure is circumferentially disposed about the optical axis, while the outer structure is circumferentially disposed about the inner structure and has an outer face. Each arm has proximal portion adjacent the inner structure and a distal portion adjacent the outer structure that is bifurcated in a radial direction from the proximal portion. The intraocular lens also has an outer surface defined by outer surfaces of the plurality of arms and an outer surface of the outer structure.

Abstract: The present invention pertains to accommodating intraocular lens (AIOL) assemblies including a haptics system for self-anchoring implantation in a human eye's annular ciliary sulcus for retaining an AIOL at a desired position along the human eye's visual axis, and an accommodation measurement implant (AMI) for determining accommodation and accommodation forces in an experimental set-up including an animal's eye.

Abstract: A refractive intraocular lens (104) and method of locating the lens within the eye and attaching the lens to the iris. The refractive intraocular lens (104) may be attached via a staple (230), a fastener (312), anchor (412) or by the tip of the haptic (118). The intraocular lens (104) works in combination with the human crystalline lens to treat conditions selected from the group consisting of myopia, hyperopia and astigmatism.

Abstract: Folding patterns for intraocular lenses are provided.

Abstract: An intraocular lens system for implantation in the human eye, haptic system and method include an intraocular lens formed of a transparent biocompatible material for replacing the natural lens of the eye. The lens includes an outer periphery and an optical axis. There is a haptic system for securely anchoring the intraocular lens in the posterior chamber of the eye. The haptic system includes at least two haptic portions formed of a rigid biocompatible material that are connected to and extend outwardly from the outer periphery the lens in a plane substantially perpendicular to the optical axis of the lens for holding the lens in the eye. Each haptic portion has an outer edge that is sized and shaped to extend from the lens to the scleral wall of the posterior chamber of the eye.

Abstract: An ophthalmic lens for providing enhanced vision includes a finished optic comprising a base optic and a membrane. The base optic has an anterior surface and an opposing posterior surface, at least one of the surfaces having a first value of a surface quality parameter. The base optic also includes a membrane including an inner surface and an outer surface, the inner surface covering one or more of the surfaces of the base optic. The outer surface has a second value of the surface quality parameter, wherein the second value is greater than the first value.

Abstract: Devices, systems, and methods useful in treating an eye are provided herein. Certain embodiments of the devices, systems, and methods may be particularly suitable in maintaining separation of an anterior capsule and a posterior capsule of an evacuated lens capsule of an eye. Certain embodiments of the devices, systems, and methods may be particularly suitable for reducing scarring in the visual field of an eye having a capsulorhexis, among other things.

Abstract: An intraocular lens assembly for increased depth of focus has a frame configurated to vault posteriorly in an eye and an optic attached thereto. Pressure from ciliary muscle contraction moves the optic anteriorly to focus the eye for near vision.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: An open chamber, accommodative, intraocular lens system operable to be positioned within the interior of an evacuated capsular bag of a human eye. The present invention provides new haptic cross-sections, novel complex lens structures by introduction of the concept of a lens ledge, fixation of haptics to lenses at a lens ledge, structural solutions to provide customized fitted correction, and accordion structural solutions to ease the insertion of complex lenses into the capsular bag of the eye.

Abstract: A single-optic accommodative lens system comprising two intraocular elements. The two intraocular elements are designed to be located within the capsular bag to extend depth of focus and/or restore accommodation following extraction of a natural lens. A first intraocular element comprises a circumferential capsular ring having interlock features to couple to and control the dynamic vault response of a second intraocular element. This second intraocular element comprises an intraocular lens (IOL) having an optic and a plurality of haptics and is designed to move axially in response to changes in the geometry of the eye capsule and thus provide a range of accommodative power. The IOL further comprises interlock features complementary to the interlock features of the first intraocular element for coupling the IOL to the capsular ring in a manner that provides for controlled movement of the IOL in response to capsular forces.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: A radially segmented apodized diffractive multifocal IOL for ocular implant is provided. The ocular implant can comprise a radially segmented apodized diffractive multifocal intraocular lens optic and a number of haptics. The radially segmented apodized diffractive multifocal IOL may pass optical energy in both photopic and mesopic conditions. The radially segmented apodized diffractive multifocal IOL includes a number of radially segmented apodization zones, each radially segmented apodization zones having a unique focal length. The haptics mechanically couple to the apodized diffractive multifocal IOL optic in order to position and secure the apodized diffractive multifocal IOL within the eye. The radially segmented apodized diffractive multifocal IOL may include both a diffractive region and a refractive region.

Abstract: In a first aspect, the invention provides an IOL having an optic with a peripheral section including one or more visually observable markers formed on the optic peripheral section and located within the visually observable zone of a surgeon viewing the IOL in the implanted condition through the pupil. In a second aspect of the invention, the IOL peripheral section includes an edge provided with a plunger engagement segment configured to inhibit off-axis movement of a plunger tip when engaged therewith.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: Unitary accommodating intraocular lenses (AIOLs) including a haptics system for self-anchoring in a human eye's ciliary sulcus and a resiliently elastically compressible shape memory optical element having a continuously variable Diopter strength between a first Diopter strength in a non-compressed state and a second Diopter strength different than its first Diopter strength in a compressed state. The unitary AIOLS include an optical element with an exposed trailing surface and are intended to be used with a discrete base member for applying an axial compression force against the exposed trailing surface from a posterior direction. Some unitary AIOLs are intended to be used with either a purpose designed base member or a previously implanted standard in-the-bag IOL. Other unitary AIOLs are intended to be solely used with a purpose designed base member.

Abstract: Disclosed is an intraocular lens that is inserted inwardly into a capsular sac. One embodiment of the present invention provides an intraocular lens inserted inwardly into a capsular sac including an optic portion including a first optic body whose central region has a smaller thickness than a circumference of the central region and a second optic body coupled to the first optic body and whose central region has the same or higher thickness as/than the first optic body; and a haptic portion including a connection bar coupled to the optic portion and first support bar coupled to a circumference of the connection bar to be in contact with an inner surface of the capsular sac.

Abstract: The implant according to the invention is intended to be used as a replacement for an orbita bottom and optionally also for the medial orbita wall. The implant comprises the form of a single-piece preformed plate or grid which comprises a first segment, a second segment and a third segment. The first segment is designed in accordance with the form of the orbita bottom and the second segment is designed according to the form of the medial side-wall. The first and second segments adjoin each other along a first preset breaking line. The third segment adjoins the first segment and is arranged for fixing the implant to the lateral orbita edge.

Abstract: A thin intraocular lens for inhibiting posterior capsular opacification (PCO) includes an optic having an anterior concave region, a posterior concave region, a sharp edge which extends posteriorly and between the posterior concave region and at least a portion of an outer-most peripheral edge surface.

Abstract: A thin IOL capable of insertion through a small incision into the capsular bag of an eye includes haptics having free ends configured to absorb compressive forces resulting from shrinkage of the capsular bag in the weeks following surgery.

Abstract: A device and method for maintaining the shape and/or position of an opening formed by a capsulorhexis.

Abstract: An IOL having a depressed inner optic area and a thickened or raised peripheral outer lip or rim integrally formed with the optic. Such a design reduces the mass of the IOL, making the lens easier to insert in a very small incision, without damaging the optic or compromising the stability of the IOL.

Abstract: In one aspect, the present invention provides a two-element ophthalmic lens in which a lateral shift of the elements relative to one another can cause a variation not only in a spherical power provided by the lens but also in spherical aberration exhibited by that lens. In some implementations, the thickness profiles of the two elements are designed such that the variation in spherical aberration is positively correlated with that of the spherical power of the lens.

Abstract: A one-piece intraocular lens realizing adhesion of the intraocular lens to the inner surface of a capsule more advantageously by viscosity imparted to the intraocular lens, and being deployed more positively after it is inserted into the capsule and secured therein while being positioned at a specified location. The intraocular lens has an optical portion (12) and supporting portions (16, 16) that are formed integrally with a soft material exhibiting viscosity, wherein viscosity reducing portions (32, 32) having irregularities are formed on at least one-end faces of the supporting portions (16, 16) in the longitudinal direction.

Abstract: An atmospheric pressure chemical vapor deposition apparatus has been developed for partially coating acrylic based intraocular lenses. In one embodiment intraocular lenses may be coated with a hydrophilic material comprising silicone dioxide and polyethylene glycol. In another embodiment the haptics may be coated with hydrophilic material, which aids in the post implantation unfolding of the lenses while not diminishing posterior bag adhesion of the hydrophobic surface of the untreated optic portion.

Abstract: The invention relates to a multifocal phakic intraocular lens having three focal regions having varying radii of curvature. When properly structured and placed, the lenses of the invention provide near, far and intermediate vision. The lens may also comprise a fenestration which permits flow of aqueous through the fenestration to provide nutrition to the anterior lens epithelium as well as the corneal endothelium.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and hinged portions longitudinally connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: A multi-part IOL which is insertable through an opening as small as about 1 mm without deforming the haptic, is described. This IOL may be used in the anterior chamber of the eye for phakic or aphakic lenses. After insertion of the haptic into the eye, any type of lens may be attached, especially by use of cleats. The haptic is a high modulus skeletal frame, and may be assembled with lower modulus material. An eyelet may be provided on the lens allowing a cleat on the haptic to firmly attach to the optic.

Abstract: A system and method for inserting an intraocular lens in a patient's eye includes a light source for generating a light beam, a scanner for deflecting the light beam to form an enclosed treatment pattern that includes a registration feature, and a delivery system for delivering the enclosed treatment pattern to target tissue in the patient's eye to form an enclosed incision therein having the registration feature. An intraocular lens is placed within the enclosed incision, wherein the intraocular lens has a registration feature that engages with the registration feature of the enclosed incision. Alternately, the scanner can make a separate registration incision for a post that is connected to the intraocular lens via a strut member.

Abstract: Intraocular lenses for implanting within the natural capsular bag of the human eye having features on the outer ends or portions of the lenses to fixate the lens within the natural capsular bag following implantation.

Abstract: An apparatus and method for reducing intraocular pressure in a patient's eye is provided. A deformable intraocular member having a relaxed state with a relaxed profile having a first width, a first energized state with a first profile having a second width, and a second energized state with a second profile having a third width is provided. The deformable intraocular member relaxed state width is greater than the width of a lens capsule which surrounds a lens of the patient's eye prior to cataract surgery. The second energized state width is greater than the patient's lens capsule width after cataract surgery and smaller than the width in the relaxed state. The deformable intraocular member in the second energized state is configured to urge deformation of the lens capsule to thereby promote opening of a trabecular meshwork and canal of Schlemm of the patient's eye to promote drainage of aqueous humor from an anterior chamber and reduce intraocular pressure in the patient's eye.

Abstract: An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. The region of contact between the optic and the haptic extends into the edge of the optic, similar to the interface between a bicycle tire and the rim that holds it in place. The haptic may be stiffer than the optic. The haptic may have the same refractive index as the optic. The haptic may include a saddle-shaped portion in contact with the adjustable optic, with a convex profile along an optical axis; and a concave profile in a plane perpendicular to the optical axis.

Abstract: The invention relates to an improved intraocular lens. According to the invention, the haptic (3) support part (4), elevation view, takes the form of a flat, closed, semi-circular loop having a constant thickness at rest. The proximal end of the loop extends from the distal part of a connecting stalk (5) which extends essentially tangential to the periphery of the optical part (2) and in parallel with the vertical diameter (d1) of the optical part. The haptic (3) support part (4) forms an angle of approximately 30° with the horizontal diameter (d2) of the optical part (2).