Method Of Manufacturing Prosthetic Device Patents (Class 623/901)
  • Patent number: 7794645
    Abstract: The present invention relates to a method for preparing a biodegradable piece for medical use including the steps of: a) preparing a mixture including glycerol and sebacic acid, b) pouring said mixture into a one-piece mould made of elastic material, c) placing the mould containing said mixture on a support, d) placing the support into a chamber with controlled temperature and vacuum level until a polymer having the desired consistency is obtained, e) removing the support from the chamber and allowing it to cool down to room temperature, and f) removing the piece thus obtained from the mould.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: September 14, 2010
    Assignee: Teknimed S.A.
    Inventors: Alain Leonard, Cyril Sender
  • Patent number: 7785363
    Abstract: The ePTFE structure includes an ePTFE tubular structure having opposite ends and a longitudinal axis. The ePTFE tubular structure is formed from rotating the opposite ends relative to one another in a direction of rotation about the longitudinal axis. The ePTFE tubular structure has a node and fibril micro-structure in which substantially all of the fibrils are oriented in the direction of rotation.
    Type: Grant
    Filed: August 15, 2007
    Date of Patent: August 31, 2010
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Julio Duran, Krzysztof Sowinski, Jamie S. Henderson
  • Patent number: 7747305
    Abstract: The present invention is directed to a computer aided design method for producing an implant for a patient prior to operation comprising the steps of: generating data with a non-invasive 3D (3-dimensional) scan of the patient's defect site that digitally represents the area that will receive the implant; designing and validating an implant on a computer based on digital data generated from a volume image of the patient; and fabricating the implant based solely on the implant design data generated on computer.
    Type: Grant
    Filed: December 9, 2005
    Date of Patent: June 29, 2010
    Assignee: Case Western Reserve University
    Inventors: David Dean, Kyoung-June Min, Robert A. Ratcheson
  • Patent number: 7727283
    Abstract: The present invention relates to an implant for stabilizing body tissue. The implant includes a core formed of a material which expands when contacted with liquid and a retainer which at least partially encloses the core.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: June 1, 2010
    Assignee: P Tech, LLC.
    Inventor: Peter M. Bonutti
  • Patent number: 7611653
    Abstract: Methods of manufacturing prosthetic devices for use as an artificial meniscus are disclosed. In some embodiments, the methods include injection molding a resilient core material, tensioning reinforcing fibers around the injection molded core, and injection molding an outer layer to embed the reinforcing fibers within the prosthetic device. In some instances the core material is a polycarbonate polyurethane and the reinforcing fibers are made of ultra-high molecular weight polyethylene (UHMWPE) having a lower melting temperature than the polyurethane. In one particular embodiment, the core material is Bionate 80A and the reinforcing fibers are made of Dyneema. In other embodiments, methods for manufacturing a reinforced material for use in prosthetic devices is disclosed.
    Type: Grant
    Filed: April 9, 2008
    Date of Patent: November 3, 2009
    Assignee: Active Implants Corporation
    Inventors: Jacob Jonathan Elsner, Gal Zur, Avraham Shterling, Noam Weissberg
  • Patent number: 7603192
    Abstract: The present invention relates to a method of designing an orthopedic implant in which a plurality of samples of the bone are selected and a CT scan of each of the samples of the bone is taken so that the data from the CT scan can be used to generate a 3D graphical solid body model of each of the sample of the bone. The 3D graphical models are placed into a category of one or more of average, small, and large, and the center of mass and an X, Y and Z plane for each model is determined. The 3D graphical models for one category is assembled and aligned at the center of mass to create a categorized composite 3D graphical solid body model of the bone. The categorized composite 3D graphical model is sectioned at a specified interval to create a lofted contoured surface of a selected thickness which is cut to create a categorized implant profile.
    Type: Grant
    Filed: February 13, 2007
    Date of Patent: October 13, 2009
    Assignee: Orthohelix Surgical Designs, Inc.
    Inventors: Amanda Martin, Dustin Ducharme, Lee A. Strnad
  • Patent number: 7597710
    Abstract: A multiple-sided medical device comprises a frame comprising wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration which a generally serpentine shape. The device is pushed from a delivery catheter into the lumen of a duct or vessel and may include one or more barbs for anchoring purposes. A full or partial covering of fabric or other flexible material such as DACRON, PTFE, or a collagen-based material such as small intestinal submucosa (SIS), may be sutured or attached to the frame using heat or pressure welding crimping, adhesive, or other techniques to form an occlusion device, a stent graft, or an implantable, intraluminal valve such as for correcting incompetent veins in the lower legs and feet.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: October 6, 2009
    Assignee: Cook Biotech, Inc.
    Inventor: Joseph F. Obermiller
  • Patent number: 7575593
    Abstract: A method of manufacturing a drug loaded stent includes applying a photo resistant coating to at least a portion of a stent framework and removing at least a portion of the photo resistant coating from the stent framework. The method further includes applying an etchant to at least a portion of the stent framework and forming a plurality undercut drug reservoirs in the stent framework based on applying the etchant. A stent for treating a vascular condition includes a stent framework, a plurality of undercut reservoirs formed within the stent framework and a therapeutic agent disposed within at least a portion of the plurality of undercut reservoirs.
    Type: Grant
    Filed: January 30, 2007
    Date of Patent: August 18, 2009
    Assignee: Medtronic Vascular, Inc.
    Inventors: Susan Rea, Jeff Allen
  • Patent number: 7540880
    Abstract: A stent is differentially coated to accommodate areas of high strain. A therapeutic coating is applied to only those areas of the stent that do not experience high strain. This allows a therapeutic coating to be chosen for its elution characteristics, for example, rather than for its ability to withstand high strain. An elastic coating may be applied to the areas of high strain. The elastic coating may or may not include a therapeutic agent.
    Type: Grant
    Filed: November 2, 2006
    Date of Patent: June 2, 2009
    Assignee: Medtronic Vascular, Inc.
    Inventor: John Nolting
  • Patent number: 7494614
    Abstract: A sintering schedule to allow the reliable formation of inorganic or ceramic materials, exemplified using porous calcium polyphosphate samples to be used for forming novel implants for bone interfacing applications. The key to the successful definition of the process was the determination of the factors affecting the crystallization temperature of the powders that are gravity sintered to form porous samples of desired density and with a pore size range suitable for the particular application.
    Type: Grant
    Filed: July 11, 2003
    Date of Patent: February 24, 2009
    Inventors: Robert M. Pilliar, Jenshong Hong, J. Paul Santerre
  • Patent number: 7481835
    Abstract: This disclosure provides a description of medical devices with polymeric cobwebbing disposed near the surfaces of the medical device. This cobwebbing can contain drug(s) and can enhance the mechanical and chemical function of intraluminal stents. Methods of using these devices and methods of preparing the devices are disclosed, as well.
    Type: Grant
    Filed: October 29, 2004
    Date of Patent: January 27, 2009
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen Dirk Pacetti, Hung Manh Le, Anthony Andreacchi, Manish Gada
  • Patent number: 7483558
    Abstract: A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: January 27, 2009
    Assignee: MicroVention, Inc.
    Inventors: George R. Greene, Jr., Robert F. Rosenbluth, Brian J. Cox
  • Patent number: 7462200
    Abstract: The present invention provides a method for tissue grafting. The method includes obtaining tissue harvested from an individual, obtaining allograft material, placing the allograft material in a chamber, adding the tissue to the allograft material in the chamber with force to create graft material, and implanting the graft material in the individual.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: December 9, 2008
    Assignee: Marctec, LLC
    Inventor: Peter M. Bonutti
  • Patent number: 7447558
    Abstract: An apparatus is described that uses cameras arranged on, in, or about a structure adapted to fit over, around, or about an object to be measured. Projectors are arranged on, in, or about the structure to project light toward the object. The projectors and/or the cameras may be electronically connected to a computer processor which controls their operation. A light pattern is projected onto the object to be measured while the cameras capture images of the object from several angles about the object. The data collected from the images taken of the pattern on the object may be used to form a mathematical three-dimensional data model of the object. The three-dimensional model may be displayed in digital form on a visual display device of a personal computer. The three-dimensional model of the object may be used in the manufacture of fitments or coverings for the object. In one example, the apparatus is used by a prosthetist to map the stump of an amputee to properly fit the amputee with a prosthetic device.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: November 4, 2008
    Assignee: The Ohio Willow Wood Company
    Inventor: Gregory C. Pratt
  • Patent number: 7429346
    Abstract: An orthopedic implant device and method is disclosed. Specifically, a knee mold system is disclosed, including elastic tibial and femoral molds, each of which may be configured and dimensioned as a unitary mold for in situ placement during a surgical procedure. Each mold may be manufactured from an elastic material that may be disposable. The tibial mold may further comprise a sidewall forming a cavity, markings for relative depth measurement, and depth rings for use as a guide for scoring, cutting, and/or trimming and tearing away an excess portion of the tibial mold. The femoral mold may further comprise a sidewall defining a cavity, two legs extending from a body of the femoral mold for forming the artificial condyles, and an eyelet for aiding in placement and removal of the femoral mold. The resulting prosthetic tibial and femoral components may form an articulation surface that mimics, at least in part, the natural articulation surface of the knee.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: September 30, 2008
    Assignee: Ortho Development Corporation
    Inventors: Michael D. Ensign, Matthew M. Lowe, E. Marc Mariani, Michael H. Bourne
  • Publication number: 20080234836
    Abstract: A socket for connecting a prosthetic limb to the residual limb of a amputee, including an adapter having at least one resin port extending therethrough and a generally conical composite material extending from the adapter. The composite material further includes a resin matrix and a multilayer triaxially woven preform embedded in the matrix. The preform is woven directly onto a positive mold of the residual limb. The adapter is positioned generally at the apex of the generally conical composite material. The adapter protrudes through the composite material.
    Type: Application
    Filed: June 21, 2004
    Publication date: September 25, 2008
    Inventor: Douglas Taylor
  • Patent number: 7422607
    Abstract: The present invention provides processes for fixation of biological tissue and/or post-fixation treatment of such tissue that result in modified tissues with reduced susceptibility to in vitro calcification when used in prosthetic devices. The invention also relates to calcification resistant biological tissue and to methods of using such tissue.
    Type: Grant
    Filed: August 23, 2005
    Date of Patent: September 9, 2008
    Inventors: Henry W. Oviatt, Neal K. Vail
  • Publication number: 20080172121
    Abstract: A medical device which defines a lumen for flowing a bodily fluid from an upstream end of the device to a downstream end thereof is disclosed. The device has a luminal wall (14) that extends between the upstream and downstream ends and defines the lumen within which the fluid flows. The wall exhibits a succession of protuberances spaced from each other along the length of the device. Each protuberance has a flank facing upstream (54) and a flank facing downstream (64), the flank facing upstream extending into the fluid flow so that a radially outermost part of the flow of fluid from the upstream to the downstream end of the device impinges on the upstream flank and is thereby caused to reverse its flow, and flow upstream from the upstream flank to the downstream flank of the next adjacent protuberance upstream, creating micro-vortices between two adjacent protuberances.
    Type: Application
    Filed: October 21, 2005
    Publication date: July 17, 2008
    Inventors: Hans Scholz, Karen Petzold, Ulf Kruger
  • Publication number: 20080140209
    Abstract: A glenoid component apparatus for shoulder arthroplasty includes a bearing portion and a stem portion connected to the bearing portion. The stem portion is modeled from a normalized glenoid vault morphology. A method for making a glenoid component for shoulder arthroplasty includes obtaining a model of a normalized glenoid vault morphology and producing a stem portion of the glenoid component based on the model.
    Type: Application
    Filed: September 20, 2006
    Publication date: June 12, 2008
    Applicant: DePuy Products, Inc.
    Inventors: Joseph P. Iannotti, Kimerly A. Powell
  • Publication number: 20080133026
    Abstract: An artificial bone includes a bone-shaped hollow metal body confining a sealed space and having two opposite closed ends, and a porous structure disposed in the sealed space. A method for making the artificial bone includes the steps of: positioning a metal tube in a bone-shaped mold cavity of a mold, hydro-forming the metal tube into a bone-shaped hollow tube in the bone-shaped mold cavity by injecting a high pressure fluid into the metal tube, disposing a crumple of metal wire into the bone-shaped hollow tube, depositing a metal coating on the metal wire and an inner surface of the bone-shaped hollow tube to form a porous structure in the bone-shaped hollow tube, and sealing the bone-shaped hollow tube.
    Type: Application
    Filed: October 20, 2006
    Publication date: June 5, 2008
    Inventors: Sio-Hou LEI, Kai-Lu WANG, Barry CHEN, Wenny KAO
  • Patent number: 7371255
    Abstract: A stent for insertion into a blood vessel is made from a sheet having a longitudinal axis and a first portion and a second portion. The first portion has a proximal end and a distal end and a first lateral side and a second lateral side with the lateral sides of the first portion substantially parallel to the longitudinal axis and disposed apart from each other a first distance. The second portion has a proximal end and a distal end and a first lateral side and a second lateral side with the lateral sides of the second portion substantially parallel to the longitudinal axis and disposed apart from each other a second distance that is less than the first distance. The proximal end of the second portion communicates with the distal end of the first portion. The first lateral side of the first portion is connected to the second lateral side of the first portion and the first lateral side of the second portion is connected to the second lateral side of the second portion to form the stent.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: May 13, 2008
    Assignee: Medinol Ltd.
    Inventors: Jacob Richter, Gregory Pinchasik
  • Patent number: 7371068
    Abstract: A system and method for an improved surgical workflow development includes creating and editing a modifiable module used to direct a medical procedure through a sequence of images and functions included in the module. A plurality of users may review and/or evaluate the module to determine what, if any, edits to the module are required. Evaluations of the module may include a research evaluation, a cadaver evaluation or a clinical evaluation. A scripting tool may be used to create or edit the module, where the scripting tool includes a computer programming software application. The module may be stored on a computer-readable memory accessible by a plurality of computers and/or display devices connected to a network. In this way, the system and method provide for rapid dynamic development of surgical workflows contained in modules.
    Type: Grant
    Filed: July 22, 2004
    Date of Patent: May 13, 2008
    Assignee: General Electric Company
    Inventors: Charles Frederick Lloyd, Gregory David Stern, Thomas C. Kienzle, Jon Thomas Lea
  • Patent number: 7371067
    Abstract: The invention provides a system for virtually designing a medical device conformed for use with a specific patient. Using the system, a three-dimensional geometric model of a patient-specific body cavity or lumen is reconstructed from scanned volume images such as obtained x-rays, magnetic resonance imaging (MRI), computer tomography (CT), ultrasound (US), angiography or other imaging modalities. Knowledge of the physical properties of the cavity/lumen is obtained by determining the relationship between image density and the stiffness or elasticity of tissues in the body cavity or lumen and is used to model interactions between a simulated device and a simulated body cavity or lumen.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: May 13, 2008
    Assignees: The Johns Hopkins University School of Medicine, Agency for Science, Technology & Research (A*Star)
    Inventors: James H. Anderson, William R. Brody, Chee-Kong Chui, Yiyu Cai, Yaoping Wang, Wieslaw L. Nowinski
  • Patent number: 7356379
    Abstract: A method of socket design and fabrication for Below-the-Knee (BK) amputees that utilizes manual measurements. This method, known as BK by Measurement, utilizes a manual measurement procedure where predetermined points are identified and measurements are taken of a patient's residual limb. These measurements are recorded and thereafter entered into a software package enabling customization by the fabrication facility. Prosthetic components fabricated in accordance with the present invention provide a custom fit, while not relying on more expensive digital imaging technology. The invention also provides a method and associated system for recording and retrieving fabrication and/or fitting data associated with a prosthetic component for use with a particular patient, which can include affixing to the prosthetic component a strip debossed with indicia unique to the particular patient or prosthetic component.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: April 8, 2008
    Assignee: Prosthetic Design, Inc.
    Inventors: Tracy C. Slemker, Robert Hoskins, Lucinda Busch, Scott R. Schall, Ralph Simmons
  • Patent number: 7351367
    Abstract: A method of forming a prosthetic residual limb test socket utilizes an adapter bracket having generally smooth sidewalls in which a corresponding plurality of removable posts are received. The adapter bracket is secured to a model of the residual limb of a patient, and a socket forming material is applied about at least a portion of the model and the adapter bracket. The socket forming material covers the plurality of removable posts but not the lower mounting face of the adapter bracket. The adapter bracket is removable and reusable. In a further aspect, a method is provided for forming a prosthetic residual limb socket based upon a test socket, in which a casting anchor is positioned within the test socket, the casting anchor being engaged with an alignment member extending out through a hole in the test socket. A molding material is introduced into the test socket so as to at least partially encase the casting anchor, and the molding material is allowed to set to form a model.
    Type: Grant
    Filed: April 12, 2004
    Date of Patent: April 1, 2008
    Assignee: Bionix Prosthetic Solutions, Inc.
    Inventor: Verner M. Swanson, Sr.
  • Patent number: 7344560
    Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, an endoprosthesis includes a first portion having a first width, and a second portion having a second width different than the first width, wherein the first and second portions have different grain sizes.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: March 18, 2008
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Daniel J. Gregorich, Jonathan S. Stinson
  • Patent number: 7329366
    Abstract: The present invention relates to a method of polishing an implantable medical device. The method may include positioning an implantable medical device on a support. At least a portion of a surface of the implantable medical device may include a polymer. A fluid may be contacted with at least a portion of the surface of the positioned implantable medical device. In an embodiment, the fluid may be capable of dissolving at least a portion of the polymer at or near the surface of the implantable medical device. The method may further include allowing the fluid to modify at least a portion of the surface of the positioned medical device. A majority of the contacted fluid may be removed from the surface of the implantable medical device. In certain embodiments, the modified portion of the surface may be substantially less thrombogenetic and substantially more mechanically stable than an unmodified surface.
    Type: Grant
    Filed: June 18, 2004
    Date of Patent: February 12, 2008
    Assignee: Advanced Cardiovascular Systems Inc.
    Inventors: David C. Gale, Syed F. A. Hossainy
  • Publication number: 20080004715
    Abstract: A method and kit for forming a definitive prosthetic socket directly on a residuum without the use of a water hardenable material. A chamber surrounding a web of braided fibers is created on the residuum via the use of inner and outer protective sheaths. A hardenable or curable material for forming the prosthetic socket is injected into the chamber around the web. Pressure is applied around the chamber to form the definitive prosthetic socket.
    Type: Application
    Filed: June 28, 2007
    Publication date: January 3, 2008
    Inventor: Sigurdur Asgeirsson
  • Publication number: 20070299520
    Abstract: A device includes a sterilizing system configured to sterilize an implantable device and includes a coating system configured to apply an osteal functional coating to the implantable device.
    Type: Application
    Filed: June 26, 2006
    Publication date: December 27, 2007
    Applicant: WARSAW ORTHOPEDIC, INC.
    Inventors: Hai H. Trieu, Jeffrey H. Nycz, Michael C. Sherman, Jon C. Serbousek
  • Publication number: 20070293965
    Abstract: Methods and systems are described for receiving a parameter relating to a specific patient, and for customizing one or more attributes of a stent ex situ as an at-least-roughly contemporaneous response to receiving the parameter relating to the specific patient or for customizing one or more junctions of a stent ex situ in response to the received parameter relating to the specific patient.
    Type: Application
    Filed: September 22, 2006
    Publication date: December 20, 2007
    Inventors: Edward K.Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Clarence T. Tegreene, Lowell L. Wood
  • Publication number: 20070293966
    Abstract: Methods and systems are described for receiving a parameter relating to a specific patient and for configuring a stent with a flow occlusion portion in response to receiving the parameter relating to the specific patient.
    Type: Application
    Filed: September 29, 2006
    Publication date: December 20, 2007
    Inventors: Edward K.Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Clarence T. Tegreene, Lowell L. Wood
  • Publication number: 20070293963
    Abstract: Methods and systems are described for receiving a parameter relating to a specific patient, and for customizing one or more attributes of a stent ex situ as an at-least-roughly contemporaneous response to receiving the parameter relating to the specific patient or for customizing one or more junctions of a stent ex situ in response to the received parameter relating to the specific patient.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 20, 2007
    Inventors: Edward K.Y. Jung, Robert Langer, Eric C. Leuthardt, Royce A. Levien, Robert W. Lord, Mark A. Malamud, John D. Rinaldo, Clarence T. Tegreene, Lowell L. Wood
  • Patent number: 7306756
    Abstract: A method for making an encapsulated stent-graft having an essentially tubular configuration with a central longitudinal lumen and having a first diameter and a second diameter, wherein the first diameter is larger than the second diameter. The stent-graft may include a self-expanding stent and a first and second tube of biocompatible material between which the stent is positioned. The stent-graft may also include an interlayer member between the first and second tube. The method generally includes applying pressure and heat to a stent-graft assembly to form a monolithic layer of biocompatible material around the stent.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: December 11, 2007
    Assignee: Bard Peripheral Vascular, Inc.
    Inventors: Tarun J. Edwin, Brendan McCrea, Christopher E. Banas
  • Publication number: 20070276491
    Abstract: A mold assembly for the in situ formation of a prosthesis in an annulus located in an intervertebral disc space between adjacent vertebrae of a patient. The mold assembly includes at least a first mold having at least one interior cavity adapted to be located in the intervertebral disc space. At least a first lumen has a distal end fluidly coupled to the mold at a first location. One or more discrete reinforcing structures are located in the intervertebral disc space with the mold. One or more biomaterials are provided to be delivered to the interior cavity through the first lumen. The at least partially cured biomaterial, the reinforcing structures and the mold cooperating to form the prosthesis.
    Type: Application
    Filed: May 24, 2006
    Publication date: November 29, 2007
    Applicant: DISC DYNAMICS, INC.
    Inventors: Michael AHRENS, Erik O. MARTZ, Ronald BURKE, Benjamin F. CARTER
  • Publication number: 20070270969
    Abstract: Three-dimensional welded-woven materials are disclosed. In particular, an orthopedic implant comprises a welded-woven material to provide lubrication and wear resistance.
    Type: Application
    Filed: May 15, 2007
    Publication date: November 22, 2007
    Inventor: Steven R. Schmid
  • Patent number: 7294409
    Abstract: Methods for fabricating a medical device having at least one porous layer include providing a medical device having at least one alloy and removing at least one component of the alloy to form the porous layer. Although methods may be used to make stent devices with porous layers, any other suitable medical device may be made having one or more porous layers. An alloy may include any suitable combination of metals and sometimes a combination of metal and non-metal. In some embodiments, one or more of the most electrochemically active component(s) of an alloy are removed by the dissolving (or “dealloying”) process, to leave a porous matrix behind. The porous matrix layer may then be infused with one or more therapeutic agents for enhancing treatment of a patient.
    Type: Grant
    Filed: November 13, 2003
    Date of Patent: November 13, 2007
    Assignee: University of Virgina
    Inventors: Whye-Kei Lye, Kareen Looi, Michael L. Reed
  • Patent number: 7283883
    Abstract: The present invention provides a method and a device for producing an orthosis model for a patient. The method comprises the input of patients' data, the determination of a curvature type of the patient's spine to be treated from a predefined number of curvature types in dependence on the patient's data, and the selection of at least one orthosis model from a predefined number of models of orthoses in dependence on the specific curvature type. The device comprises a data input device being designed for inputting patients' data, a data base containing a number of curvature types and a number of orthoses models, a curvature determination device designed to determine a curvature type from the data base in dependence on the patients' data, and an orthosis model selection device designed to select at least one orthosis model from the data base in dependence on the determined curvature type.
    Type: Grant
    Filed: March 17, 2004
    Date of Patent: October 16, 2007
    Assignee: Ortho Solutions OHG
    Inventors: Jenny Voit, Dino Gallo
  • Patent number: 7278195
    Abstract: Method for producing a coated medical support device capable of insertion into the body, the method including the procedures of applying a coating to a section of a work-piece, positioning the work-piece in the vicinity of an electromagnetic field generator, and substantially proximate a forming mandrel, inducing electromagnetic forces in the work-piece which accelerate the work-piece toward the forming mandrel, and forming the work-piece to a medical support device, by changing the original physical configuration of the work-piece to a second physical configuration, the forming mandrel having a mandrel physical configuration, the second physical configuration being influenced by the mandrel physical configuration.
    Type: Grant
    Filed: June 3, 2003
    Date of Patent: October 9, 2007
    Assignee: Israel Aircraft Industries Ltd.
    Inventors: Abraham Baum, Elisha Hoch, Israel Schnitzer, Lior Kacir, Felix Rabinovich, Reuben Ilia
  • Publication number: 20070233234
    Abstract: A stent is formed as a substantially tubular body possessing an outer diameter suitable for insertion into an organism, with the body being expandable when a radially outwardly directed expansion force is applied from inside the tubular body. The stent is fabricated from an alloy containing at least two noble metals selected among gold, platinum, silver, and copper, with the alloy possessing a density of not less than 14 g/cm3, a proof stress of not less than 300 MPa, and a elongation-to-break of not less than 20%.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 4, 2007
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventor: Yousuke Moriuchi
  • Publication number: 20070224678
    Abstract: The present invention provides a functionalized ceramic body for in vitro and in vivo use comprising a calcium aluminate containing phase that is functionalized with a linker group comprising at least one of an organic acid molecule, a phosphonic acid, an amine, and N,N-dicyclohexylcarbodiimide for providing a reactive location for the attachment of at least one of another chemical moiety or a biologically active moiety to the ceramic body. Functionalized compositions are provided comprising a calcium aluminate containing phase that is functionalized with the linker group. Methods of manufacturing a functionalized artificial prosthesis that may be used as artificial bones, joints, in-vitro support structures, and in-vivo support structures for cells, tissues, organs, and nerve growth and regeneration are disclosed.
    Type: Application
    Filed: March 23, 2007
    Publication date: September 27, 2007
    Inventors: Kenneth A. McGowan, Ellen S. Gawalt
  • Patent number: 7273493
    Abstract: The present invention provides for reinforced and drug eluting stent-grafts and related methods of implanting and manufacturing the stent-grafts. A stent-graft of the present invention may include a tubular stent, a biocompatible covering surrounding the stent, and a supporting collar coupled to the proximal end of the stent-graft. A drug agent may be applied to a textured external surface layer of the biocompatible covering, or alternatively to a space between the textured external surface layer and a smooth luminal surface layer of the biocompatible covering, and allowed to elute over time into a wall of a body lumen after the stent-graft is deployed. The collar of the stent-graft absorbs pressure exerted on the stent-graft by fluid flow within the body lumen in order to minimize potential damage to the stent-graft, and may also include barbs to further secure the stent-graft to the body lumen.
    Type: Grant
    Filed: May 8, 2006
    Date of Patent: September 25, 2007
    Inventor: Walter J. Ledergerber
  • Publication number: 20070219622
    Abstract: A stent-graft assembly is provided for a variety of medical treatments. The stent-graft assembly comprises an inner graft, an outer graft, and at least one stent disposed circumferentially between the inner graft and outer graft. The inner graft is attached directly to the outer graft circumferentially at a first location proximal to a first stent, and further attached directly to the outer graft circumferentially at a second location distal to the first stent, thereby forming a first pocket that houses the first stent. Neither the inner graft nor the outer graft is attached directly to the stent, permitting improved stent flexibility and reducing manufacturing complexity.
    Type: Application
    Filed: March 12, 2007
    Publication date: September 20, 2007
    Applicant: Cook Incorporated
    Inventor: Shyam SV Kuppurathanam
  • Patent number: 7255770
    Abstract: The present invention concerns methods for joining flexible polymer workpieces using light energy. These methods, referred to as laser welding, can be used to join thermoplastic or thermoset polymers. The laser welding method of the invention is applicable to the creation or repair of any article requiring the bonding of two flexible polymer components or a flexible polymer component and an inflexible polymer component.
    Type: Grant
    Filed: August 12, 2002
    Date of Patent: August 14, 2007
    Assignee: Mentor Corporation
    Inventor: Lawrence Y. Wissman
  • Publication number: 20070162119
    Abstract: A prefabricated tympanic membrane prosthesis includes a piece of collagen sheet processed with a diluted solution of formalin. The piece of collagen sheet is molded on a forming surface of a tool having a shape resembling a natural tympanic membrane of a human subject. The piece of collagen sheet is processed with a diluted solution of formalin so that the resulting tympanic membrane prosthesis retains the shape of the forming surface. The tympanic membrane prosthesis is semi-rigid, yet flexible, and is packaged in a substantially rigid container to protect it shape during shipment and storage.
    Type: Application
    Filed: January 8, 2007
    Publication date: July 12, 2007
    Applicant: Medical College of Georgia Research Institute, Inc.
    Inventor: Alan J. Johnson
  • Patent number: 7240414
    Abstract: A method of sizing, resizing or reshaping the interior of a prosthetic device includes placing a lightweight moldable or shape assuming, pliable material that adheres and hardens on the interior sides of a socket of a prosthetic device. An end of a residual limb is placed into the socket causing the moldable material to conform to the shape of the residual limb. The limb is maintained in position for a few minutes in the socket until the moldable material has sufficiently hardened. After hardening, the molded material is dressed down, sanded or feathered to remove any burrs or sharp edges. Low spots or holes may be filled in with more moldable material and the fitting process repeated.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: July 10, 2007
    Inventor: Matthew T. Taylor, Sr.
  • Patent number: 7239937
    Abstract: A method of socket design and fabrication for Below-the-Knee (BK) amputees that utilizes manual measurements. This method, known as BK by Measurement, utilizes a manual measurement procedure where predetermined points are identified and measurements are taken of a patient's residual limb. These measurements are recorded and thereafter entered into a software package enabling customization by the fabrication facility. Prosthetic components fabricated in accordance with the present invention provide a custom fit, while not relying on more expensive digital imaging technology. The invention also provides a method and associated system for recording and retrieving fabrication and/or fitting data associated with a prosthetic component for use with a particular patient, which can include affixing to the prosthetic component a strip debossed with indicia unique to the particular patient or prosthetic component.
    Type: Grant
    Filed: July 21, 2005
    Date of Patent: July 3, 2007
    Assignee: Prosthetic Design, Inc.
    Inventors: Tracy C. Slemker, Robert Hoskins, Lucinda Busch, Scott R. Schall, Ralph Simmons
  • Patent number: 7238200
    Abstract: A method for making a bioprosthetic heart valve includes providing a non-contact cutting apparatus and a layer of tissue. The non-contact cutting apparatus may include a laser cutting system or high pressure water jet system. A leaflet is cut from the layer of tissue using a predefined template, and a plurality of alignment holes in the leaflet are created in the leaflet, e.g., along a peripheral edge. A support structure is provided having a plurality of alignment holes corresponding to alignment holes in the leaflet. The leaflet is secured to the support structure by securing one or more sutures through corresponding alignment holes in the leaflet and the support structure to provide a leaflet subassembly. A bioprosthetic heart valve is made by securing a set of leaflet subassemblies to a frame.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: July 3, 2007
    Assignee: Arbor Surgical Technologies, Inc.
    Inventors: Shouyan Lee, Ernest Lane
  • Patent number: 7226558
    Abstract: A high density microwall ePTFE structure and a method for making, involving the manipulation of a standard extruded ePTFE graft. The final product has the desired characteristics of high density, reduced wall-thickness, above-average radial strength and enhanced suture retention.
    Type: Grant
    Filed: February 5, 2004
    Date of Patent: June 5, 2007
    Assignee: Bard Peripheral Vascular, Inc.
    Inventors: Tim Nieman, Randy Earl Saylor, Robert Hunkins, Robert Calcote
  • Patent number: 7185597
    Abstract: A method for stitching thread onto the wall of a tubular medical implant (preferably a graft) employs a sewing machine with an elongate bobbin or a needle on an elongate element, depending on whether it is desired to sew from the outside-in or the inside-out. A motor rotates and translates the implant, which is mounted on a hollow drum, relative to the needle.
    Type: Grant
    Filed: October 27, 2000
    Date of Patent: March 6, 2007
    Assignee: Anson Medical Limited
    Inventors: Peter Phillips, Gail Beaton
  • Patent number: RE40487
    Abstract: A method for forming the outer surface of a breast prosthesis is disclosed. A digital, three-dimensional image is formed of a patient's breast using a computerized scanner. A computer-controlled milling machine utilizes the image to form a solid model of the breast. A sheet of flexible, moldable material having a uniform, precise thickness is then vacuum-formed over the breast model. A hard, two-piece mold is cast from the flexible sheet. A soft, curable material is then either poured or injected between the two pieces of the mold to form the breast prosthesis outer surface. The breast prosthesis outer surface is then turned inside out to form a shape that is a mirror image of the patient's breast.
    Type: Grant
    Filed: July 11, 2002
    Date of Patent: September 9, 2008
    Assignee: Board of Trustees of the University of Arkansas
    Inventor: L. Daniel Eaton